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Anamnestic response against bovine viral diarrhea virus and bovine herpesvirus type 1 in young Holstein heifers vaccinated with four different commercial formulations
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Gomes, Viviani

; Baccili, Camila Costa

; Marques, Raquel Sousa

; Soriano, Sergio

; Pedroso, Natália Hettwer

; Flores, Eduardo Furtado

Ciência Rural

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2024, Volume 54 N. 2 elocation e20220364

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

ABSTRACT: This study evaluated the vaccine-induced serological response after administering four commercial formulations containing Bovine Viral Diarrhea Virus (BVDV) type-1, BVDV-2, and Bovine Herpesvirus type 1 (BoHV-1) to young heifers with circulating maternal antibody titers. The study also determined the anamnestic response to vaccinations after the complete metabolization of maternal antibodies when the calves reached six months. Eighty-seven Holstein heifers were selected and randomly distributed into four experimental groups based on the vaccine administered. The four vaccine-based experimental groups were as follows: vaccine A (n = 22), vaccine B (n = 22), vaccine C (n = 24), and vaccine D (n = 19), given on the 60th, 90th, and 180th day of life, respectively. Virus-neutralization (VN) tests were performed at baseline (day 60) and 30 days after administering the second (day 120) and third doses (day 210). We analyzed the effect of vaccine group (P ≤ 0.001), day of vaccination (P ≤ 0.001), and group versus vaccine day interaction (P ≤ 0.001) for antibody titers produced against BVDV-1, BVDV-2, and BoHV-1 using the PROC MIXED method (Statistical Analysis System -SAS 9.4). Antibody titers against BVDV-1, BVDV-2, and BoHV-1 were similar at baseline and on day 60 of life. The mean antibody titers were constant and persisted against BVDV-1 in heifers immunized with vaccines A and C. Heifers immunized with vaccine A alone had a similar effect against BVDV-2. Regarding BoHV-1, the antibody titers decreased between days 60 and 210 in groups B, C, and D. The antibody titer for heifers in group A also decreased between days 60 and day 120, and an intense increase in titers was observed on day 210. After being immunized with formulations B, C, and D, the frequency of animals with titers above protective levels for BVDV-1, BVDV-2, and BoHV-1 was very low or null. Indicators of anamnestic response were observed in heifers vaccinated with formulation A only. Therefore, it can be concluded that passive immunity negatively interferes with antibody production after vaccination.

RESUMO: O objetivo desse estudo foi avaliar a resposta sorológica induzida após vacinação com quatro formulações comerciais contendo o BVDV-1, BVDV-2 e BoHV-1 em novilhas jovens com títulos de anticorpos maternos circulantes, assim como analisar uma possível resposta anamnéstica em vacinações, após a completa metabolização dos anticorpos maternais aos seis meses de idade. Foram selecionadas 87 novilhas Holandesas, distribuídas aleatoriamente em quatro grupos experimentais de acordo com as vacinas: vacina A (n = 22), vacina B (n = 22), vacina C (n = 24) e vacina D (n = 19), aplicadas aos dias 60, 90 e 180 de vida. Testes de vírus-neutralização (VN) foram realizados no momento basal (D60) e 30 dias após a aplicação da 2ª dose (D120) e 3ª dose (D210). Observou-se efeito do grupo (P ≤ 0,001), dia da vacinação (P ≤ 0,001), e interação grupo versus dia (P ≤ 0,001) para os títulos de anticorpos produzidos contra o BVDV-1, BVDV-2 e BoHV-1, por meio do comando PROC MIXED (Statistical Analysis System, versão 9,4). Os títulos de anticorpos contra o BVDV-1, BVDV-2 e BoHV-1 eram semelhantes no momento basal aos 60 dias de vida. Os títulos médios de anticorpos foram constantes e persistentes contra o BVDV-1 nas novilhas imunizadas com as vacinas A e C, porém apenas a vacina A teve este mesmo perfil contra o BVDV-2. Em relação ao BoHV-1, os grupos B, C e D apresentaram queda nos títulos de anticorpos do D60 ao D210, enquanto as novilhas do grupo A apresentaram queda do D60 ao D120, com aumento intenso dos títulos no D210. A frequência de animais com títulos acima dos protetores contra o BVDV-1, BVDV-2 e BoHV-1 foram muito baixos ou nulos após as vacinações nos animais imunizados com as formulações B, C e D. Sugere-se que a imunidade passiva interferiu negativamente na indução de anticorpos pelas vacinas, observando-se indicadores de resposta anamnéstica apenas para as novilhas vacinadas com a formulação A.

https://doi.org/10.1590/0103-8478cr20220364

Evaluation of an automatized AMBU ESSI-1 INC designed at the Instituto Nacional de Cardiología Ignacio Chávez
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Abundes-Velasco, Arturo

; Sánchez-Pérez, Efraín

; Jiménez-Rodríguez, Gian M.

; Molina-Méndez, Francisco J.

; Herrera-Elizalde, Rafael

; Pulido-Zamudio, Tomás

; Álvarez-Rosales, Humberto

; Villegas-Juache, Juan

; Aceves-Díaz-González, Sebastián

; Parra-Rodríguez, David A.

; Cruz-Enríquez, Francisco J.

; Cobos-Reyes, Farid A.

; Aguilar-Torres, Eduardo A.

; Islas-Navarro, Enid A.

; Nuñez-Gómez, José C.

; Peña-Duque, Marco A.

Archivos de cardiología de México

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dec 2023, Volume 93 N. 4 Pages 391 - 397

Abstract: Es En | Text: Es En | PDF: Es | PDF: En

Resumen Objetivo: Evaluar un dispositivo automatizado para la asistencia ventilatoria basado en un AMBU manufacturado en Marzo del 2020. Métodos: El ESSI-1 INC fue evaluado por medio de parámetros fisiológicos y mecánica pulmonar a través de pruebas de espirómetro compensatorios (TISSOT); pulmón artificial (Modelo 5600i Dual Adult PNEU VIEW SYSTEM); así como su desempeño comparado a la máquina de anestesia (AEONMED 7500) en modelos porcinos, midiendo criterios ventilatorios, hemodinámicos y gasométricos. Resultados: Este equipo (ESSI-1 INC) fue exitosamente probado por modelos mecánicos y biológicos, tales como cerdos donde su desempeño fue evaluado en términos de la variabilidad del volumen tidal, frecuencia ventilatoria, y relación I/E versus el desempeño manual de dos médicos. Todos los resultados finalizaron como se esperaba de forma satisfactoria. Conclusiones: Es un equipo seguro y efectivo, el cual debería ser probado y usado en distintas condiciones clínicas para estandarizar la seguridad ventilatoria y cuidado de pacientes que lo requieran.

Abstract Objective: The objectives of this study were to evaluate an automated device for ventilatory support based on AMBU manufactured in March 2020. Methods: The ESSI-1 INC was evaluated through pulmonary mechanics and physiology parameters through compensatory spirometer tests (TISSOTs), and an artificial lung Model5600i Dual Adult PNEU VIEW SYSTEM; it was also compared to the anesthetic ventilatory support equipment (AEONMED 7500) in porcine models, measuring ventilatory, hemodynamic and gasometric parameters. Results: This equipment (ESSI-1 INC) was successfully tested by mechanical and biological models, such as pigs in which its performance was evaluated in terms of variability of tidal volume, ventilation frequency, and I/E relationship versus the manual performance of two medical interns. All the results turned out as expected and were satisfactory. Conclusions: It is safe and effective equipment and should be tested and used in diverse clinical conditions to standardize the ventilatory safety and care of patients who require it.

https://doi.org/10.24875/acm.2200004

Manejo interdisciplinario de la obesidad y el sobrepeso en rehabilitación cardiaca: revisión de la Sociedad Mexicana para el Cuidado del Corazón
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Lara-Vargas, Jorge A.

; Pérez-Reyes, Angélica A.

; Núñez-Urquiza, Juan P.

; Navarrete de la O, Dulce M.

; Ilarraza-Lomelí, Hermes

; Leyva-Valadez, Eduardo A.

; González-Rentería, María E.

; Romero-Rendón, Minerva

; Ponce-de-León-Espíndola, Marcos

; Maldonado-Ramírez, Martha C.

; Rubio-Blancas, Aquiles

Archivos de cardiología de México

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dec 2023, Volume 93 N. 4 Pages 464 - 475

Abstract: Es En | Text: Es En | PDF: Es | PDF: En

Resumen Antecedentes: La obesidad es un trastorno multifactorial caracterizado por un aumento en la adiposidad corporal, de amplia prevalencia en nuestro país, a cualquier edad y ligada a grandes consecuencias adversas, incluyendo el desarrollo de cardiopatías. Los programas de rehabilitación cardiaca (RC) son intervenciones interdisciplinarias encaminadas no solo a restaurar la funcionalidad perdida de los pacientes que han sufrido un desenlace cardiovascular, sino también a corregir aquellos factores de riesgo que lo propiciaron y que interfieren en los resultados adaptativos del mismo. La obesidad contribuye a perpetuar el riesgo de cardiopatía y suele ser resistente a las modificaciones del estilo de vida de manera convencional. Objetivo: Establecer pautas en el reconocimiento de la obesidad con directrices de atención al paciente con cardiopatía dentro de los programas de RC y su abordaje interdisciplinario. Método: A través de una extensiva revisión bibliográfica y después de una discusión interdisciplinaria, se elaboró el presente documento para fijar una postura sobre el abordaje de la obesidad en el contexto de los programas de RC en pacientes con cardiopatía. Resultados y conclusiones: Nuestra Sociedad reconoce el abordaje interdisciplinario de los pacientes con obesidad y cardiopatía en su prevención primaria y secundaria, insta a la precisión en su diagnóstico y valoración, y recomienda que su eje primario debe estar basado en primera instancia en las modificaciones del estilo de vida (entrenamiento físico, atención nutricional e intervención psicoemocional), en tanto que la terapia farmacológica y la cirugía bariátrica pudieran ser coadyuvantes en la optimización de los resultados en pacientes selectos.

Abstract Background: Obesity is a multifactorial disorder characterized by increased body adiposity with a wide prevalence in our country, at any age, and linked to major adverse consequences, including the development of heart disease. Cardiac rehabilitation (CR) programs are interdisciplinary interventions aimed not only at restoring the lost functionality of patients who have suffered a cardiovascular outcome, but also at correcting those risk factors that led to it and that interfere with its adaptive results. Obesity contributes to perpetuating heart disease risk and is often resistant to conventional lifestyle modifications. Objective: Establish guidelines in the recognition of obesity with care guidelines for patients with heart disease within CR programs and their interdisciplinary approach. Method: Through an extensive bibliographical review and after an interdisciplinary discussion, this document was prepared to establish a position on the approach to obesity in the context of CR programs in patients with heart disease. Results and conclusions: Our Society recognizes the interdisciplinary approach of our patients with obesity and heart disease in its primary and secondary prevention, urges precision in its diagnosis and assessment, recommends that its primary axis must be based in the first instance on lifestyle modifications (physical training, nutritional care and psycho-emotional intervention), while pharmacological therapy and bariatric surgery could be coadjuvants in optimizing the results in selected patients.

https://doi.org/10.24875/acm.22000288

Third National Registry of Cardiac Rehabilitation Programs in Mexico (RENAPREC III-2022)
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Lara-Vargas, Jorge A.

; Ilarraza-Lomelí, Hermes

; García-Saldivia, Marianna

; Pineda-García, Alfredo D.

; Leyva-Valadez, Eduardo A.

; Justiniano-Cordero, Samuel

; Sahagún-Olmos, Roberto

; Zavala-Ramírez, Juana

; Cassaigne-Guasco, María E.

; Sánchez-Limón, Edgar-F

; Castañeda-López, Javier

; Cerón-Enríquez, Norma

; Ku-González, Andrés

; Arteaga-Martínez, Rodolfo

; Hinojosa-López, Tania

; Vergara-Guzmán, Jéssica

; Pérez-Vázquez, Daniel I.

; Gasca-Zamudio, Pedro D.

; Aranda-Ayala, Zulema L.

; Vacío-Reyes, Martha E.

; Reza-Orozco, Marco

; Alcocer-Gamboa, Miguel A.

; Hernández-González, Pedro A.

; Pérez-Reyes, Angélica A.

; Núñez-Urquiza, Juan P.

; Alonso-Sánchez, Jesús

; Franco-Valles, Sarahí

; Romo-Escamilla, Ricardo E.

; Nuriulú-Escobar, Patricia

; Serna-Santamaría, Iván

; Avilés-González, Jorge

; Salgado-Solorio, María C.

; Muñoz-Gutiérrez, Luz M.

; Mendoza-Díaz, Pedro M.

; Ávila-Estrada, Ángel

; Morales-Medina, Carlos

; Lara-Vázquez, Eduardo

; Rodríguez-Herrera, Paulina

; Galván-López, María

; Segoviano-Mendoza, Georgina

; De-la-Torre-Cruz, Fabiola

; Jiménez-Campos, Cecilia

; Ramírez-Meléndez, Alejandra

; Almaraz-Ríos, Alejandro

; González-Bonilla, Mezthly

; Rojano-Castillo, Jessica

; Rius-Suarez, María D.

Archivos de cardiología de México

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dec 2023, Volume 93 N. 4 Pages 405 - 416

Abstract: Es En | Text: Es En | PDF: Es | PDF: En

resumen está disponible en el texto completo

Abstract Introduction: In Mexico, cardiac rehabilitation (CR) as an interdisciplinary intervention with therapeutic impact in patients with heart disease is growing. There is the need to know actual conditions of CR in our country. Objectives: The objective of this National Registry is to follow-up those existing and new CR units in Mexico through the comparison between the two previous registries, RENAPREC-2009 and RENAPREC II-2015 studies. This is a descriptive study focused on diverse CR activities such as assistance training, and certification of health professionals, barriers, reference, population attended, interdisciplinarity, permanence over time, growth prospects, regulations, post-pandemic condition, integrative characteristics, and scientific research. Results: Data were collected from 45 CR centers in the 32 states, 75.5% are private practice units, 67% are new, 33% were part of RENAPREC II-2015, and 17 have continued since 2009. With a better distribution of CR units along the territory, the median reference of candidates for CR programs is 9% with a significant reduction into tiempo of enrollment to Phase II admission (19 ± 11 days). Regarding to previous registries, the coverance of Phases I, II, and III is 71%, 100%, and 93%, respectively; and a coverance increases in evaluation, risk stratification, and prescription, more comprehensive attendance and prevention strategies. Conclusions: CR in Mexico has grown in the past 7 years. Even there is still low reference and heterogeneity in specific processes, there are strengths such as interdisciplinarity, scientific professionalization of specialists, national diversification, and an official society that are consolidated over time.

https://doi.org/10.24875/acm.22000235

Diversidad y estructura de especies arbóreas en localidades rurales de Hualahuises, México
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Molina Guerra, Víctor Manuel

; Alanís Rodríguez, Eduardo

; Mora Olivo, Arturo

; Rubio Camacho, Ernesto A.

; González Cuellar, Andrés Tzolkin

Revista mexicana de ciencias forestales

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oct 2023, Volume 14 N. 79 Pages 344 - 354

Abstract: Es En | Text: Es En | PDF: Es | PDF: En

Resumen En este estudio se evaluó la proporción de especies arbóreas nativas respecto a las introducidas en bosques urbanos de seis zonas rurales de Hualahuises, Nuevo León (noreste de México). Para el análisis de varianza se utilizó la prueba de proporciones con un nivel de confianza de 0.95 mediante el comando prop.test en R. Se registraron 252 individuos de 32 especies distribuidas en 29 géneros y 19 familias. La familia Fabaceae fue la mejor representada con siete especies. De todos los taxones, 19 son nativos (59.37 %) y 13 introducidos (40.63 %). De acuerdo con su origen, 77.79 % de los individuos son nativos y 22.21 % introducidos. Referente a sus dimensiones, las diferencias porcentuales son mayores: las nativas representan 91.69 % de área basal, 92.36 % de área de copa, 92.22 % de área superficial de la copa y 96.78 % de volumen de copa, mientras que las no nativas presentan valores inferiores a 9.00 %. Prosopis laevigata, seguida de Vachellia farnesiana y Ebenopsis ebano presentaron los valores estructurales más altos. Las tres son nativas pertenecientes a la familia Fabaceae y juntas conforman 44.05 % de la abundancia y 63.71 % del Índice de Valor de Importancia Urbano. Con base en el análisis de varianza, las especies nativas resultaron tener mayores valores de riqueza, área basal y área superficial de copa que las introducidas en las localidades evaluadas.

Abstract In this study, the proportion of native vs. introduced tree species in urban forests of six rural areas of Hualahuises, Nuevo León (Northeast Mexico) was evaluated. For the analysis of variance, the proportions test was used with a confidence level of 0.95 through the prop.test command in R. 252 individuals of 32 species distributed in 29 genera and 19 families were recorded. The Fabaceae family was the largest represented with seven species. Of the 32 species, 19 are native (59.37 %) and 13 introduced (40.63 %). Based upon their origin, 77.79 % of the individuals are native and 22.21 % introduced. Regarding their dimensions, the percentage differences are greater: the native ones represent 91.69 % of the basimetric area, 92.36 % of the crown area, 92.22 % of the assumed crown area and 96.78 % of crown volume, while the non-natives present values lower than 9.00 %. At the species level, those with the highest structural values were Prosopis laevigata followed by Vachellia farnesiana and Ebenopsis ebano. The three species are native belonging to the Fabaceae family and together they represent 44.05 % of the abundance and 63.71 % of the Urban Importance Value Index. According to the analysis of variance, the native species turned out to have higher values of richness, basal area, and crown area than the introduced species in the assessed localities.

https://doi.org/10.29298/rmcf.v14i79.1343

Do vitamins affect the morphophysiology of lettuce in a hydroponic system?
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Vendruscolo, Eduardo P.

; Seron, Cássio de C.

; Leonel, Eduardo A. S.

; Lima, Sebastião F. de

; Araujo, Suleiman L.

; Martins, Murilo B.

; Sant’ Ana, Gabriela R.

; Oliveira, Janaina J. de

Revista Brasileira de Engenharia Agrícola e Ambiental

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sep 2023, Volume 27 N. 9 Pages 698 - 703

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

ABSTRACT Technologies once applied exclusively in conventional systems have maximized gains in hydroponic systems; however, they still need information for proper use. Thus, the study aimed to evaluate the effect of foliar application of thiamine and niacin on growth and gas exchange activities in two lettuce cultivars in an ebb and flow hydroponic system. The completely randomized design (CRD) was used with four treatments and eight replications. The treatments were as follows: T1 - control, T2 - thiamine at a concentration of 200 mg L-1, T3 - niacin at 200 mg L-1, and T4 - thiamine and niacin combined at 100 mg L-1 of each vitamin. Each experimental plot consisted of a lettuce plant. The combined application of thiamine and niacin stood out, increasing the activity of gas exchange of lettuce plants and increasing by about 30% the fresh mass, concerning the control, for both cultivars, followed by the isolated application of niacin. For thiamine, the application alone did not result in significant changes. The vitamins affect the morphophysiology of lettuce, where the use of niacin has the potential for use in hydroponic production systems. Its combined use with thiamine increases this potential, with a synergistic effect between the compounds being verified.

RESUMO Tecnologias outrora aplicadas exclusivamente em sistemas convencionais, têm maximizado os ganhos em sistemas hidropônicos, porém, necessitando ainda de informações para uma adequada utilização. Assim, o estudo teve como objetivo avaliar o efeito da aplicação foliar de tiamina e niacina sobre o crescimento e atividades de troca gasosa em duas cultivares de alface em sistema hidropônico de fluxo e refluxo. O delineamento experimental utilizado foi o inteiramente casualizado (DIC), com quatro tratamentos e oito repetições. Os tratamentos foram: T1 - controle; T2 - tiamina em concentração de 200 mg L-1; T3 - niacina em concentração de 200 mg L-1; T4 - tiamina e niacina combinadas, em concentração de 100 mg L-1 de cada vitamina. Cada parcela experimental foi constituída por um vaso, contendo uma muda de alface. A aplicação conjunta de tiamina e niacina elevou as trocas gasosas das plantas de alface, aumentando em cerca de 30% a massa fresca, em relação ao controle, para ambas as cultivares, seguida pela aplicação isolada de niacina. Para a tiamina, a aplicação de forma isolada não resultou em alterações significativas. As vitaminas afetam a morfofisiologia da alface, onde o uso da niacina tem potencial para uso em sistemas de produção hidropônicos, sendo esse potencial aumentado pelo seu uso conjunto com a tiamina, verificando-se um efeito sinérgico entre os compostos.

https://doi.org/10.1590/1807-1929/agriambi.v27n9p698-703

Estimate of carbon stock in the soil via diffuse reflectance spectroscopy (vis/nir) air and orbital remote sensing
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Faria, Ohana C. O.

; Torres, Gilmar N.

; Raimo, Luis A. D. L. Di

; Couto, Eduardo G.

Revista Caatinga

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sep 2023, Volume 36 N. 3 Pages 675 - 689

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

ABSTRACT Current procedures for determining soil organic carbon (SOC) content are costly, time-consuming, and generate polluting chemical waste. Therefore, developing new protocols using aerial and orbital remote sensing and diffuse reflectance spectroscopy (DRS) for digitally mapping the stock of soil organic carbon (CS) is essential for promoting actions of research and monitoring SOC in Brazilian soils. Given this, three areas of commercial plots in the region of the Middle North of Mato Grosso were studied, where sampling was carried out for the determination of SOC in the layer from 0 to 30 cm, evaluated by the dry combustion method and estimated through DRS in the visible to near -infrared region - Vis-NIR-SWIR/350-2500 nm). To obtain the images by aerial remote sensing, the Carcará II® Unmanned Aerial Vehicle was used, with a MicaSense® multispectral camera (RGB + NIR + RedEdge) attached. The orbital sensors used were the Sentinel 2® and Planet® satellites. This study showed that soil carbon stock values could be predicted using different modeling approaches based on field and laboratory spectral measurements. Predictive models to estimate SOC can be established using remote and near sensing, thus allowing a better understanding of spatial patterns of SOC in crop fields.

RESUMO Os procedimentos atuais de determinação do conteúdo de carbono orgânico do solo (COS) são onerosos, demorados e geram resíduos químicos poluentes. Por isso, o desenvolvimento de novos protocolos utilizando o sensoriamento remoto aéreo, orbital e a espectroscopia de refletância difusa (ERD) para o mapeamento digital do estoque de carbono orgânico do solo (EC) são imprescindíveis para o fomento de ações de pesquisa e monitoramento do COS nos solos brasileiros. Diante disso, foram estudadas três áreas de talhões comerciais na região do Meio Norte de Mato Grosso onde realizou-se a amostragem para a determinação de COS na camada de 0 a 30 cm, avaliado pelo método de combustão via seca e estimado através da ERD na região do visível ao infravermelho-próximo - Vis-NIR-SWIR/350-2500 nm) . Para obtenção das imagens por sensoriamento remoto aéreo, foi utilizado o Veículo Aéreo Não Tripulado Carcará II®, com uma câmera multiespectal (RGB + NIR + RedEdge) da marca MicaSense® acoplada. Os sensores orbitais utilizados foram o satélite Sentinel 2® e Planet®. Este estudo mostrou que os valores do estoque de carbono do solo podem ser preditos usando diferentes abordagens de modelagem com base em medições espectrais de campo e laboratório. Modelos preditivos para estimar o COS podem ser estabelecidos usando sensoriamento remoto e próximo, permitindo assim uma melhor compreensão dos padrões espaciais do COS nos campos de cultivo.

https://doi.org/10.1590/1983-21252023v36n320rc

Procalcitonina y proteína C reactiva: marcadores en el diagnóstico temprano de fuga anastomótica
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Maldonado-Hernández, Isadora G.

; Vega-Chavarría, Eduardo

; Nacud-Bezies, Yamir A.

; Cordero-Franco, Hid F.

; Palacios-Saucedo, Gerardo C.

Cirugía y cirujanos

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aug 2023, Volume 91 N. 4 Pages 542 - 549

Abstract: Es En | Text: Es En | PDF: Es | PDF: En

Resumen Objetivo: Determinar la eficacia de la procalcitonina (PCT) y la proteína C reactiva (PCR) séricas en el diagnóstico de fuga anastomótica (FA) en los pacientes sometidos a cirugía colorrectal. Método: Prueba diagnóstica en un hospital de tercer nivel. Se excluyeron los pacientes que no tuvieron mediciones preoperatorias de PCT y PCR. Se eliminaron los que cursaron con infección posoperatoria no relacionada con FA. Las medidas de eficacia diagnóstica fueron sensibilidad (S), especificidad (E), valores predictivos positivo (VPP) y negativo (VPN), razones de verosimilitud positiva (RV+) y negativa (RV−), y área bajo la curva característica operativa del receptor (AUROC). Resultados: Se analizaron 39 pacientes, de los cuales 6 (15.4%) tuvieron FA. La PCT y la PCR aumentaron al segundo día posoperatorio solo en los pacientes con FA. Los puntos de corte al día 2 fueron 1.55 ng/ml para PCT y 11.25 mg/l para PCR. La prueba más eficaz fue la PCR al día 2 (AUROC: 1.00; S: 100%; E: 96.7%; VPP: 85.7%; VPN: 100%; RV+: 33.0). Conclusiones: La PCR en el segundo día posoperatorio fue la prueba más eficaz en el diagnóstico temprano de FA en los pacientes sometidos a cirugía colorrectal, con un punto de corte inferior a lo reportado en la literatura internacional.

Abstract Objective: To determine the efficacy of serum procalcitonin (PCT) and C-reactive protein (CRP) in the early diagnosis of anastomotic leak (AL) in patients undergoing colorectal surgery. Method: Diagnostic test in a tertiary care hospital. Patients who did not have preoperative measurements of PCT and CRP were excluded. Those with postoperative infection not related to AL were eliminated. The diagnostic efficacy measures were sensitivity (Sn), specificity (Sp), positive (PPV) and negative (NPV) predictive values, positive (LR+) and negative (LR−) likelihood ratios, and area under the receiver operating characteristic curve (AUROC). Results: Thirty-nine patients were analyzed; six had AL (15.4%). PCT and CRP increased on the second postoperative day, only in patients with AL. The cut-off points at the second postoperative day were 1.55 ng/mL for PCT and 11.25 mg/L for CRP. The most efficacious test was PCR at second postoperative day (AUROC: 1.00; Sn: 100%; Sp: 96.7%; PPV: 85.7%; NPV: 100%; LR+: 33.0). Conclusions: CRP at second postoperative day was the most effective test in the early diagnosis of AL in patients undergoing colorectal surgery, with a cut-off point lower than that reported in the international literature.

https://doi.org/10.24875/ciru.22000116

Mineral content of shrubs from goat’s production systems in two seasons in an arid zone
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Rivas-García, Tomás

; Toyes-Vargas, Eduardo Alberto

; Espinoza-Villavicencio, José Luis

; Palacios-Espinosa, Alejandro

; Murillo-Amador, Bernardo

Ecosistemas y recursos agropecuarios

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aug 2023, Volume 10 N. 2 elocation e3528

Abstract: Es En | Text: Es En | PDF: Es | PDF: En

Resumen Los minerales son necesarios en la dieta de los animales para su mantenimiento, desarrollo y reproducción. El objetivo fue determinar el contenido de minerales en arbustos que consumen las cabras en una zona árida en tres sistemas de producción, durante las estaciones húmeda y seca. Las hojas, vainas tallos o flores y un suplemento se muestrearon y se determinó en 34 arbustos Ca, Mg, K, Na, P, N, Fe, Mn, Zn, Cu, B y Cl. Los arbustos en los sistemas de producción mostraron suficiente K, Ca, K, Mg, Na, B, Cl y N para las necesidades de las cabras; sin embargo, el contenido de P fue bajo. El contenido de Zn, Cu, Fe y Mn fue menor en todos los arbustos. Los resultados sugieren que, en la zona de estudio es posible utilizar forrajes no leguminosos en la dieta para mejorar su valor nutricional, debido a su contenido mayor en minerales. El sistema de producción semi-intensivo mostró que, el 58% de los minerales fue mayor en este sistema, considerado como el mejor. El contenido mineral en L. brevipes, T. lobaeformis y A. barclayana en el semi-intensivo fueron adecuados para las cabras, mientras que en el extensivo el contenido mineral fue de buena calidad nutricional con S. thurberi y C. gayana para el sistema intensivo. Los arbustos mostraron diferencias entre los macrominerales y la cantidad/calidad nutricional de estos para las cabras difiere en función del sistema de producción, la estación y los tipos de arbustos.

Abstract Minerals are needed in the diet of animals for maintenance, development, and reproduction. The aim was to determine mineral content of shrubs consumed by goats in an arid area from three production systems, during wet and dry seasons. The leaves, pods, stems, or flowers of 34 shrubs and one supplement were sampled manually and analyzed Ca, Mg, K, Na, P, N, Fe, Mn, Zn, Cu, B, and Cl. The shrubs showed enough K Ca, K, Mg, Na, B, Cl and N for goat requirements for all production systems; however, P was lower. The Zn, Cu, Fe, and Mn contents were lower in all shrubs. The results suggest that in the study area more non-legumes could be used in the goat diet to enhance nutritional value because of their higher mineral content. Considering the status of mineral content, 58% of all minerals had higher content in the semi-intensive production system, and possibly, it is the best production system. Adequate values of mineral content 58% of all minerals had higher content in the semi-intensive production system, and possibly, it is the best production system. Adequate values of mineral content were found in L. brevipes, T. lobaeformis and A. barclayana in the semi-intensive system, while in the extensive system the mineral content was of good nutritional quality with S. thurberi and C. gayana for the intensive system. The 35 shrubs showed differences among macrominerals and the nutritional quantity/quality of these minerals for goats varied depending on production system, season, and types of shrubs.

https://doi.org/10.19136/era.a10n2.3528

10.

COVID-19 Infection Changes the Functions and Morphology of Erythrocytes: A Multidisciplinary Study
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Sales, Marcos V. S.

; Tanabe, Eloiza L. L.

; Maciel, Thamilla M. S.

; Tavares, Maria C.

; Leal, Juliana G. C.

; Pinto, Larissa S.

; Pires, Keyla S. N.

; Coelho, Jorge A. P. M.

; Silva, Elaine C. O.

; Souza, Samuel T.

; Fonseca, Eduardo J. S.

; Fragoso, Thiago S.

; Aquino, Thiago M.

; Borbely, Alexandre U.

; Rocha, Ueslen

; Santos, Josué C. C.

; Leite, Ana Catarina R.

Journal of the Brazilian Chemical Society

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aug 2023, Volume 34 N. 8 Pages 1185 - 1196

Abstract: En | Text: En | PDF: En

Hematological problems are associated with Coronavirus disease 2019 (COVID-19). Respiratory impairment is the higher point studied, although without experimental studies related to the oxygen transport performed by erythrocytes. Therefore, we decided to investigate if erythrocytes from COVID-19 patients have their functionality changed. The case-control study included hospitalized patients with a positive real-time polymerase chain reaction (RT-PCR) result admitted to University Hospital. Volunteers (negative RT-PCR results) were recruited as a control group. Thus, we assessed different erythrocytes parameters, oxidative stress markers, and biophysical studies using whole blood and isolated hemoglobin. We found a decrease of 51% in oxygen uptake and reduced antioxidant enzyme activity in COVID-19 patients compared to controls. Raman spectrometry showed structural changes in the hemoglobin and lipids of the erythrocytes from COVID-19 patients; thus, these results were consolidated with an increase in Young’s modulus in erythrocytes followed by morphology changes. Besides, isolated hemoglobin from COVID-19 patients has a distinct interaction profile using a ligand model compared to the control. COVID-19 leads to structural, functional, and morphological damage to human erythrocytes. Our data showed structural and molecular changes and induction of oxidative stress in erythrocytes by COVID-19, a new perspective on the contribution of erythrocytes to a respiratory commitment in COVID-19.

https://doi.org/10.21577/0103-5053.20230031

11.

Fast and Environmentally Friendly Method for Simultaneous Determination of Hydrochlorothiazide, Losartan and Potassium by Capillary Electrophoresis with Capacitively Coupled Contactless Conductivity Detection
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Marra, Mariana C.

; Ribeiro, Michelle M. A. C.

; Muñoz, Rodrigo A. A.

; Richter, Eduardo M.

Journal of the Brazilian Chemical Society

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aug 2023, Volume 34 N. 8 Pages 1208 - 1213

Abstract: En | Text: En | PDF: En

Losartan potassium and hydrochlorothiazide are often combined in pharmaceutical formulations for the treatment of hypertension. Therefore, the determination of these compounds in a single run is highly desirable for rapid quality control applications. The present study describes an ultra-fast (ca. 85 injections h-1) and environmentally friendly method based on capillary electrophoresis (CE) with capacitively coupled contactless conductivity detection for simultaneous quantification of potassium, losartan and hydrochlorothiazide. Cation (potassium) and anions (losartan and hydrochlorothiazide) were analyzed in a single run using a background electrolyte composed by 10.0 mmol L-1 boric acid (pH = 9.0, adjusted with sodium hydroxide). The limits of detection were 4.0, 3.0 and 10.0 μmol L-1 for potassium, losartan and hydrochlorothiazide, respectively. The proposed method is simple, fast, with minimal waste generation, and accurate (recovery values between 98 and 102%). The results obtained with the CE method were statistically similar (95% confidence level) to those obtained by high-performance liquid chromatography (losartan and hydrochlorothiazide) and flame photometry (potassium).

https://doi.org/10.21577/0103-5053.20230033

12.

Clinical and Urodynamic results of the Argus T® sling in moderate and severe male stress urinary incontinence after radical prostatectomy – a 5 year prospective study.
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Carvalho, Adilson P.

; Silva, André B.

; Lebani, Bruno R.

; Pinto, Eduardo R.

; Felipe, Mariana R.

; Skaf, Milton

; Girotti, Marcia E.

; Zequi, Stenio C.

; Sacomani, Carlos A. R.

; Almeida, Fernando G.

International braz j urol

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aug 2023, Volume 49 N. 4 Pages 452 - 461

Abstract: En | Text: En | PDF: En

ABSTRACT Purpose: Sling as a therapeutic option for male stress urinary incontinence (SUI) has been reviewed in the last two decades, as it is a relatively simpliest surgery compared to artificial urinary sphincter and has the ability to modulate urethral compression. This study aims to evaluate the efficacy, rate of complications, quality of life and the effects on bladder emptying of the Argus T® compressive and ajustable sling in moderate and severe male SUI treatment. Materials and Methods: Men eligible for stress urinary incontinence treatment after radical prostatectomy were recruited and prospectively evaluated, from March 2010 to November 2016. It was selected outpatient men with moderate and severe SUI, after 12 months of radical prostatectomy, who have failed conservative treatment. All patients had a complete clinical and urodynamic pre and post treatment evaluation, by means of clinical history, physical examination, urine culture, 1-hour pad test and ICIq-SF questionnaire. The UDS was performed after 12, 18 and 24 months postoperatively. Results: Thirty-seven men underwent sling surgery, 19 patients (51.4%) with moderate and 18 (48.6%) with severe SUI. The minimum follow-up time was 5 years. Overall, we had a success rate of 56.7% at 60 months follow-up. After surgery, we did not observe significant changes in the urodynamic parameters evaluated during the follow-up. No patient had urodynamic bladder outlet obstruction (BOO) after sling implantation. Readjustment of the Argus T® sling was performed in 16 (41%) of the patients and 51% of the patients reported some adverse event. Conclusion: We demonstrate a long-term efficacy and safety of Sling Argus T® as an alternative to moderate and severe male SUI treatment. Furthermore, in our study bulbar urethra compression does not lead to bladder outlet obstruction.

https://doi.org/10.1590/s1677-5538.ibju.2023.0003

13.

Biostimulants increase growth and yield of second-crop maize
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Thomé, Silvia E. N.

; Lima, Sebastião F.

; Oliveira, Izabela C. de

; Contardi, Lucymara M.

; Vendruscolo, Eduardo P.

; Andrade, Maria G. de O.

; Cordeiro, Meire A. S.

; Arguelho, Jeysielli C.

; Oliveira, Janaina J. de

Revista Brasileira de Engenharia Agrícola e Ambiental

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jul 2023, Volume 27 N. 7 Pages 550 - 558

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

ABSTRACT The use of biostimulants in second-crop maize (Zea mays) can promote higher physiological activity in plants, resulting in higher grain yield. This study aimed to evaluate the effects of phytohormones and nicotinamide on growth and yield traits of second-crop maize. The statistical design used was a randomized block design arranged in a factorial scheme with two doses of phytohormones (0 and 500 mL ha-1) × five concentrations of nicotinamide (0, 200, 400, 600, and 800 mg L-1) with four replications. The use of biostimulants favored all variables evaluated for the maize crop. The isolated use of phytohormones and nicotinamide promoted grain yields of 6089.6 and 6242.5 kg ha-1, respectively, representing gains of 6.0 and 11.6%, respectively, compared with the control. The application of 800 mg L-1 nicotinamide resulted in the highest maize grain yield. The use of phytohormones and nicotinamide, isolated or associated, was favorable for the growth characteristics and grain yield of second-crop maize. A synergistic effect was noted between phytohormones and nicotinamide on the first ear insertion height and number of rows per ear.

RESUMO O uso de bioestimulantes no milho segunda safra (Zea mays) pode promover maior atividade fisiológica das plantas, resultando em maior produtividade de grãos. Assim, este trabalho teve como objetivo avaliar as características de crescimento e produtividade do milho segunda safra sob aplicação de fitormônios e nicotinamida. O delineamento estatístico utilizado foi em blocos casualizados dispostos em esquema fatorial com 2 doses de fitohormônios (0 e 500 mL ha-1) × 5 concentrações de nicotinamida (0, 200, 400, 600 e 800 mg L-1) com quatro repetições. O uso dos dois bioestimulantes favoreceu todas as variáveis avaliadas para a cultura do milho. O uso isolado de fitormônios e nicotinamida promoveu produtividades de grãos de 6.089,6 e 6.242,5 kg ha-1, representando respectivamente, ganhos de 6,0 e 11,6%, em relação à testemunha. A aplicação de 800 mg L-1 de nicotinamida proporcionou maior produtividade de grãos de milho. O uso de fitohormônios e nicotinamida, isolados ou associados, foram favoráveis às características de crescimento e produtividade do milho segunda safra. Houve efeito sinérgico de fitormônios e nicotinamida para altura de inserção da primeira espiga e o número de fileiras por espiga.

https://doi.org/10.1590/1807-1929/agriambi.v27n7p550-558

14.

Epidemiology and severity of traumatic dental injuries in permanent teeth: A 20-year retrospective study
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Vieira, Walbert A.

; Pereira, Andrea C.

; Lazzari, Jaqueline

; Pecorari, Vanessa G.A.

; Gomes, Brenda P.F.A.

; Almeida, José Flávio A. de

; Ferraz, Caio C. R.

; Santos, Eduardo C. A.

; Vargas-Neto, Júlio

; de-Jesus-Soares, Adriana

Brazilian Dental Journal

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jun 2023, Volume 34 N. 3 Pages 1 - 8

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

Abstract This study aimed to assess the traumatic dental injuries (TDIs) in permanent dentition among patients who attended at the outpatient clinic of a Brazilian dental school, during the last 20 years, and to investigate factors associated with the severity of these injuries. Clinical records of patients who attended a specialized center for dental trauma care in Brazil presenting at least one TDI in a permanent tooth, between the years 2000 and 2019, were reviewed. The data recorded were sex, age, affected arch, etiology, number, and type of the teeth affected, and classification and severity of the TDIs. The diagnosis and classification of the TDIs were based on the guidelines of the International Association of Dental Traumatology (IADT). The severity of each patient's injuries was defined as mild, moderate, or severe. Descriptive statistics, chi-square and multinomial regression analyses were used to evaluate the results. The significance level was set at 5%. A total of 837 clinical records were included, totaling 2357 teeth. Males were more prevalent than females. The patients' age ranged from 5 to 71 years. The most common traumas were avulsion (n=512) and uncomplicated enamel-dentin fracture (n=488). Univariate analyses showed that there was a statistically significant association between age group (p=0.004), etiology (p=0.000) and number of teeth affected (p=0.000) with severity of dental trauma. In conclusion, TDIs that occurred in Piracicaba and region are epidemiologically similar to those found worldwide, and that more severe injuries are related to age range, etiology and number of teeth affected.

Resumo Esse estudo objetivou avaliar as injúrias dentárias traumáticas (IDTs) na dentição permanente entre os pacientes que compareceram ao ambulatório de uma faculdade de odontologia brasileira, durante os últimos 20 anos, e investigar fatores associados à severidade dessas lesões. Os registros clínicos dos pacientes que compareceram a um centro especializado de atendimento em traumatismo dentário no Brasil apresentando pelo menos uma IDT em dente permanente, entre os anos de 2000 e 2019, foram revisados. Os dados registrados foram sexo, idade, arco dental afetado, etiologia, número e tipo dos dentes afetados, e classificação e severidade das IDTs. O diagnóstico e a classificação das IDTs foram baseados nas diretrizes da Associação Internacional de Traumatologia Dentária (AITD). A gravidade das lesões de cada paciente foi definida como leve, moderada ou severa. Estatísticas descritivas, teste qui-quadrado e análises de regressão multinomial foram usadas para avaliar os resultados. O nível de significância foi fixado em 5%. Um total de 837 registros clínicos foi incluído, totalizando 2357 dentes. O sexo masculino foi mais prevalente que o feminino. A idade dos pacientes variou de 5 a 71 anos. Os traumas mais comuns foram avulsão (n=512) e fratura não-complicada do esmalte-dentina (n=488). As análises univariadas mostraram que houve associação estatisticamente significativa entre a faixa etária (p=0,004), etiologia (p=0,000) e número de dentes afetados (p=0,000) com a gravidade do traumatismo dentário. Em conclusão, as IDTs que ocorreram em Piracicaba e região são epidemiologicamente semelhantes aos encontrados em todo o mundo, e que lesões mais graves estão relacionadas à faixa etária, etiologia e número de dentes afetados.

https://doi.org/10.1590/0103-6440202305257

15.

Mathematical Mapping Study of Synthetic Antioxidants Behavior in Biodiesel: Application of the Self-Organized Feature Map (SOFM) and Multilayer Perceptron (MLP)
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Clemente, Marco A. J.

; Silva, Heloisa H. P.

; Campos, Julia W.

; Silva, Nathan F.

; Sousa, Eduardo G.

; Mantovani, Ana C. G.

; Angilelli, Karina B.

; Borsato, Dionisio

Journal of the Brazilian Chemical Society

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may 2023, Volume 34 N. 5 Pages 684 - 693

Abstract: En | Text: En | PDF: En

The objective of the present work was to apply self-organizing feature maps (SOFM) and multilayer perceptron (MLP) to evaluate the protective capacity of tert-butylhydroquinone (TBHQ), butylhydroxyanisole (BHA), and butylhydroxytoluene (BHT) antioxidants against the biodiesel oxidation reaction. For this, the antioxidant concentration and the biodiesel compliance parameters were used as continuous input variables and the type of antioxidant as a categorical. The SOFM proved to be an adequate tool for the classification of biodiesel samples containing antioxidants. The performance of the 5 most active networks of the model ranged from 89 to 99% for training, testing, and validation with an error below 1.42 × 10-4. Statistical tests applied to validate the model showed no significant difference between predicted and experimental values. The global sensitivity analysis showed that the relative protection factor (RPF) contributed with 34.89%, the antioxidant with 31.49%, the induction period with 10.69%, the water content with 6.00%, and the others all together with 16.93% in the construction of the regression models by MLP.

https://doi.org/10.21577/0103-5053.20220139

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