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au:Dias, Ricardo S.

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Influence of Homogenization and Annealing Temperatures on the Microstructure, Mechanical Properties, and Passive Properties of Cold Rolled 2205 Duplex Stainless Steel
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Assumpção, Raphael F.

; A. Júnior, Ricardo

; Silva, Amanda P.

; Dias, Francislaynne L.

; Santos, Dagoberto B.

; Sicupira, Dalila C.

Materials Research

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2022, Volume 25 elocation e20220066

Abstract: En | Text: En | PDF: En

Abstract The effects of homogenization, cold working, and subsequent annealing treatment were studied on the microstructural evolution, mechanical properties, and passive properties of duplex stainless steel (DSS). A hot-rolled 2205 DSS was subjected to two processing routes. In one, the DSS goes through an extra homogenization step at 1100 °C for 1800 s before cold rolling. After cold deformation (~75%) the specimens were isothermally annealed at 900, 1000, and 1100 °C for 180 s. The microstructure evolution was studied by optical microscopy (OM), scanning electron microscopy (SEM) and X-ray diffraction (XDR). Mechanical properties were evaluated by microhardness and tensile tests. The electrochemical behaviors were investigated by potentiodynamic measurements, electrochemical impedance spectroscopy (EIS) and Mott-Schottky analysis (MS). Chemical composition of the lowest corrosion resistant passive film was assessed by X-ray photoelectron spectroscopy (XPS). Homogenization before cold rolling lowered strain hardening, slowing the microstructural transformation process. The thermomechanical process did not change the semiconductor type of the passive films. However, grain refinement after annealing improved the corrosion resistance in borate buffer solution. Cold rolling significantly decreased the corrosion resistance. The passive film of the specimen homogenized before cold rolling had the lowest corrosion resistance and high amounts of Cr(OH)3 and FeO.

https://doi.org/10.1590/1980-5373-mr-2022-0066

Association between non-typhoidal Salmonella isolated from commercial poultry sheds and associated factors in Paraná, Brazil: Cross-sectional retrospective study
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Silva, Nayara Dias da

; Laurindo, Ellen Elizabeth

; Martins, Camila Marinelli

; Silveira, Ricardo Michael Pinheiro

; Silveira, Claudinei Taborda da

; Santin, Elizabeth

Arquivos do Instituto Biológico

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2021, Volume 88 elocation e00402020

Abstract: En | Text: En | PDF: En

ABSTRACT The epidemiology of salmonellosis in poultry is complex, which makes it difficult to identify the origin and spread of this disease in poultry farms. The aims of this study were to characterize the spatial distribution of Salmonella enterica in epidemiological units in Paraná, Brazil; and to investigate correlations between this microorganism and associated factors. Among the epidemiological units, 78 of 243 (32.10%) were positive. Spatially, the northwestern and western regions had higher concentrations of positive cases than the other regions. In bivariate analyses, the presence of other animal species in the epidemiological unit (prevalence ratio, PR = 0.64; 95% confidence interval, CI = 0.43–0.95; p = 0.022) and proximity to establishments at risk (PR = 0.51; 95% CI = 0.32–0.81; p = 0.001) did not influence positivity, but the average population per poultry shed (between 30,501 and 32,500; PR = 2.57; 95% CI = 1.72–3.83; p = 0.001) was associated with Salmonella positivity. Multiple logistic regression demonstrated that the average population per poultry shed, presence of surrounding risk-posing establishments and presence of surrounding poultry sheds produced a significant multiple model for S. enterica. The results indicated that the presence of S. enterica may be related to higher density broiler in poultry sheds, presence of surrounding poultry sheds, proximity between positive and negative epidemiological units and altitude of the municipality. The information obtained showed that some factors were related to positivity for this microorganism and emphasizes the importance of serotyping to obtain other epidemiological data.

https://doi.org/10.1590/1808-1657000402020 1 downloads

Climate risk and seasonal forage production of Marandu palisadegrass in Brazil
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BRUNETTI, HENRIQUE B.

; CAVALCANTI, PÓRTYA P.

; DIAS, CARLOS TADEU S.

; PEZZOPANE, JOSÉ RICARDO M.

; SANTOS, PATRÍCIA M.

Anais da Academia Brasileira de Ciências

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2020, Volume 92 N. 3 elocation e20190046

Abstract: En | Text: En | PDF: En

Abstract This study aimed to characterize Brachiaria brizantha cv. Marandu seasonal production (seasonality) and its variation (climate risk) yearlong throughout Brazil. Data from weather stations in Brazil (1963-2009), were associated with an empirical herbage accumulation rate (HAR; kg DM ha-1 day-1) model which considers growing degree-days adjusted by a drought attenuation index. Simulations were performed under 20, 40, 60 and 100 mm of soil water holding capacities (SWHCs). HAR’s means and standard deviations were calculated for the seasons of the year. Thereafter, cluster analysis and calculations were performed to gather similar weather stations and characterize seasonality and climate risk indexes. Cluster analysis resulted in four Groups per SWHC. The north of Brazil (Group 1) presented the lowest seasonality and climate risk indexes and low need for precautions. In the middle west (Group 2), the seasonality index ranged from medium-high to high. Winter and Summer presented the lowest and highest production, respectively. In the south of Brazil, some regions in the southeast and northeast (Group 3), Winter presented the lowest production and highest climate risk index, probably due to low temperatures. The northeast (Group 4) presented a seasonality index that ranged from medium-high to very high and low productions.

https://doi.org/10.1590/0001-3765202020190046 877 downloads

Cattle trade between and within biomes in the state of Mato Grosso, Brazil
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Negreiros, Rísia L.

; Grisi-Filho, José H.H.

; Dias, Ricardo A.

; Ferreira, Fernando

; Homem, Valéria S.F.

; Ferreira Neto, José S.

; Ossada, Raul

; Amaku, Marcos

Pesquisa Veterinária Brasileira

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nov 2018, Volume 38 N. 11 Pages 2023 - 2028

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO: A análise dos padrões de trânsito animal pode ajudar a identificar estabelecimentos sob um risco potencialmente maior de introdução de doença infecciosa. Foram analisadas a rede de trânsito de bovinos no estado do Mato Grosso, Brasil, e uma base de dados com tamanho de rebanho, ambas de 2007. Há três biomas diferentes em Mato Grosso: Amazônia, Cerrado e Pantanal. A análise do trânsito animal entre e dentro dos biomas nos permitiu caracterizar quão conectados são os biomas e quão intenso é o trânsito interno dentro de cada bioma. Conduzimos as seguintes análises: 1) se o rebanho bovino está concentrado em alguns estabelecimentos no estado todo e em cada bioma; 2) sobre o número absoluto e a frequência relativa de bovinos movimentados entre os biomas; e 3) quais são os propósitos mais frequentes para o trânsito animal. Encontramos que 20% dos estabelecimentos possuíam 81,15% do rebanho total do estado. Estes estabelecimentos podem ser importantes para o espalhamento de doenças infecciosas, mas também para a implementação de estratégias de vigilância e controle. A maior parte do trânsito foi dentro do estado (97,1%), e o trânsito interno dentro de cada bioma foi predominante (88,6%). Um percentual alto de movimentos do Pantanal (48,6%) foi para o Cerrado, o bioma que recebeu mais bovinos para abate, engorda e reprodução (62,4%, 56,8% e 49,1% de todos os movimentos para abate, engorda e reprodução, respectivemente). Os principais propósitos para o comércio de bovinos foram engorda (43,5%), abate (31,5%) e reprodução (22,7%). Movimentos para abate presumivelmente oferecem um baixo risco para espalhamento de doença. Em contraste, movimentos para engorda e reprodução (66,2% de todos os movimentos) podem contribuir para o aumento do risco de espalhamento de doenças infecciosas.

ABSTRACT: The analysis of animal movement patterns may help identify farm premises with a potentially high risk of infectious disease introduction. Farm herd sizes and bovine movement data from 2007 in the state of Mato Grosso, Brazil, were analyzed. There are three different biomes in Mato Grosso: the Amazon, Cerrado, and Pantanal. The analysis of the animal trade between and within biomes would enable characterization of the connections between the biomes and the intensity of the internal trade within each biome. We conducted the following analyses: 1) the concentration of cattle on farm premises in the state and in each biome, 2) the number and relative frequency of cattle moved between biomes, and 3) the most frequent purposes for cattle movements. Twenty percent (20%) of the farm premises had 81.15% of the herd population. Those premises may be important not only for the spread of infectious diseases, but also for the implementation of surveillance and control strategies. Most of the cattle movement was intrastate (97.1%), and internal movements within each biome were predominant (88.6%). A high percentage of movement from the Pantanal was to the Cerrado (48.6%), the biome that received the most cattle for slaughter, fattening and reproduction (62.4%, 56.8%, and 49.1% of all movements for slaughter, fattening, and reproduction, respectively). The primary purposes for cattle trade were fattening (43.5%), slaughter (31.5%), and reproduction (22.7%). Presumably, movements for slaughter has a low risk of disease spread. In contrast, movements for fattening and reproduction purposes (66.2% of all movements) may contribute to an increased risk of the spread of infectious diseases.

https://doi.org/10.1590/1678-5150-pvb-5661 875 downloads

Synthesis and Antimicrobial Activity of Glycosylated 2-Aryl-5-amidinobenzimidazoles
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Souza, Thiago B. de

; Oliver, Josidel C.

; Gomes, Ana Paula B.

; Aragão, Cícero Flávio S.

; Ferreira, Leandro S.

; Nogueira, Fernando Henrique A.

; Dias, Amanda Latércia T.

; Alves, Ricardo J.

Journal of the Brazilian Chemical Society

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jun 2018, Volume 29 N. 6 Pages 1304 - 1317

Abstract: En | Text: En | PDF: En

A series of new glycosylated 2-aryl-5-amidinobenzimidazoles derived from four different carbohydrates (D-glucose, D-galactose, N-acetyl-D-glucosamine and lactose) were synthesized by the condensation of the appropriate 4-formyl-3-methoxyphenyl glycoside with 4-amidino- or 4-N-isopropylamidino-ortho-phenylenediamine hydrochloride. All the compounds were properly characterized by high resolution mass spectrometry, uni- and bidimensional 1H and 13C nuclear magnetic resonance and then were evaluated for their antibacterial and antifungal potential. Considering the antifungal potential of them, two derivatives were active against Candida parapsilosis at 96.4 µmol L-1 and another was active against this same strain at 83.5 µmol L-1. In addition, one benzamidine showed activity against Candida glabrata at 97 µmol L-1. Considering the antibacterial potential of these compounds, six of them showed better activity against three different stains: three of them with IC50 of 96.4, 97 and 83.5 μmol L-1 against Gram-positive Micrococcus luteus, the other two with IC50 96.5 and 96.4 μmol L-1 against Gram-positive Enterococcus faecalis and one against Gram-negative Escherichia coli at 90.5 µmol L-1. These findings suggest this structural pattern can be employed for design of more potent agents for discovery of new antimicrobial drug candidates.

https://doi.org/10.21577/0103-5053.20170227 710 downloads

Sobre a melhoria da produção e da avaliação de periódicos científicos no Brasil
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Ponce, Branca Jurema

; Almeida, Maria Elizabeth Biaconcini de

; Freitas, Silvana Alves

; Silva, Cícero Barbosa da

; Anjos, Daniela

; Pietri, Emerson de

; Prieto, Rosângela Gavioli

; Dias, Érika S. de Almeida C.

; Camargo, Evani

; Branco, Jordanna Castelo

; Souza, José dos Santos

; Bizelli, José Luís

; Siman, Lana Mara de Castro

; Muzzeti, Luci Regina

; Reis, Magali dos

; Martins, Edna

; Rosito, Margaréte May Benkenbrock

; Bissoto, Maria Luisa

; Castro, Monica Rabelo de

; Gimenes, Nelson

; Gualtieri, Regina

; Silva, Regis

; Ribeiro, Ricardo

; Lemes, Sebastião de Souza

Ensaio: Avaliação e Políticas Públicas em Educação

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dec 2017, Volume 25 N. 97 Pages 1032 - 1044

Abstract: Pt En Es | Text: Pt En Es | PDF: Pt | PDF: En | PDF: Es

Resumo O documento que apresentamos é fruto da reflexão de Editores de Periódico Científicos ligados ao FEPAE Sudeste – Fórum de Editores de Periódicos da Área de Educação Sudeste – e expressa preocupações concretas sobre as condições materiais para a realização de seu trabalho, assim como, sobre os critérios de avaliação que vêm sendo utilizados para qualificar suas revistas. Orçamentos mais enxutos, o desmonte de estruturas universitárias que sustentavam muitas revistas acadêmicas e indexadores que cada vez mais complicam os procedimentos operacionais envolvidos na produção editorial, fragilizam as revistas nacionais. Falta de visibilidade sobre os processos de avaliação, ausência de diálogo sobre resultados e questões ligadas à periodicidade do QUALIS trazem uma insegurança para os autores que têm nos periódicos o veículo de divulgação de suas práticas e teorias. Queremos, assim, adensar a discussão com a comunidade científica e a Agência Reguladora Governamental, sobre os destinos que estarão reservados aos Periódicos Científicos brasileiros.

Abstract The document we presented is the result of the reflection of Editors of Scientific Journals connected to FEPAE Southeast and expresses concrete concerns about the material conditions for the realization of its work and about the evaluation criteria that have been used to qualify its journals. Cheaper budgets, dismantling of university structures that supported many academic journals and indicators which everytime complicate even more the operational procedures involved in editorial production, undermine the national journals. Lack of visibility about the evaluation procedures, absence of dialogue about results and questions connected to the Qualis frequency bring uncertainty for the authors who have in the journals a vehicle for sharing its practices and theories. This way we want to deepen the discussion with the scientific community and the Regulatory Governmental Agency - CAPES - about the destinations reserved to Brazilian Scientific Journals.

Resumen El documento que presentamos es fruto de la reflexión de Editores de Revistas Científicas ligadas al FEPAE Sudoeste – Foro de Editores de Revistas del Área de Educación Sudoeste – y expresa preocupaciones concretas sobre las condiciones materiales para la realización de su trabajo, así como sobre los criterios de evaluación que vienen siendo utilizados para calificar sus revistas. Presupuestos más restrictos, el desmonte de estructuras universitarias que sustentaban muchas revistas académicas e indexadores que cada vez complican más los procedimientos operacionales involucrados en la producción editorial, fragilizan a las revistas nacionales. Falta de visibilidad sobre los procesos de evaluación, ausencia de diálogo sobre resultados y cuestiones ligadas a la periodicidad del QUALIS representan incertidumbre para los autores que ven a las revistas como un vehículo de divulgación de sus prácticas y teorías. Queremos, así, enriquecer la discusión con la comunidad científica y la Agencia Reguladora Gubernamental, sobre los destinos que estarán reservados a las Revistas Científicas brasileras.

https://doi.org/10.1590/s0104-40362017002501032 1749 downloads

GRAFT TAKES OF TOMATO ON OTHER SOLANACEOUS PLANTS
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ZEIST, ANDRÉ RICARDO

; RESENDE, JULIANO TADEU VILELA DE

; GIACOBBO, CLEVISON LUIZ

; FARIA, CACILDA MARIA DUARTE RIOS

; DIAS, DIEGO MUNHOZ

Revista Caatinga

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jun 2017, Volume 30 N. 2 Pages 513 - 520

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO O presente trabalho teve como objetivo avaliar o pegamento de enxertia de tomateiro, em diferentes espécies de solanáceas e por diferentes métodos de enxertia. Foram produzidas para enxerto mudas de tomateiro da cultivar Santa Cruz Kada®. O delineamento experimental utilizado foi o inteiramente casualizado, com os tratamentos arranjados em esquema fatorial 9 x 2, avaliando-se como porta-enxerto: os acessos de minitomate 0224-53, RVTC 57, RVTC 20 e 6889-50 (Solanum lycopersicum L); as espécies silvestres de tomateiro Solanum habrochaites var hirsutum ‘PI-127826’ e Solanum pennellii ‘LA716’; duas outras espécies Solanum, cubiu (Solanum sessiliflorum) e fisales (Physalis peruviana); e o tomateiro cultivar Santa Cruz Kada® como testemunha (auto-enxertia), e avaliados dois métodos de enxertia: fenda cheia; e encostia. Aos quinze dias após a enxertia, as plantas foram avaliadas quanto ao: índice de pegamento de enxertia; comprimento de raiz; altura das plantas; número de folhas; área foliar; massa seca das raízes, do caule e das folhas; e relação massa seca da parte aérea/massa seca das raízes. Com base nos resultados obtidos, foi possível verificar que o índice de pegamento e o desenvolvimento vegetativo das plantas após a enxertia em tomateiro foi influenciado significativamente pela interação (porta-enxerto x método de enxertia). Dentre os porta-enxertos avaliados, todos podem ser recomendados, exceto o acesso de minitomate 6889-50 (S. lycopersicum L.) e a espécie S. pennellii. Para os porta-enxertos cubiu e fisales recomenda-se a utilização do método de enxertia por fenda cheia, e para os porta-enxertos acesso de (minitomate 0224-53, RVTC 57 e RVTC 20; e espécie S. habrochaites) o método de encostia.

ABSTRACT This paper aimed to assess tomato grafting on different solanaceous species through two grafting methods. Scions were cut from cultivar Santa Cruz Kada seedlings. A fully randomized experimental design was carried out with treatments in a 9 x 2 factorial scheme. As rootstocks, four accessions of mini-tomatoes (0224-53, RVTC 57, RVTC 20 and 6889-50 - Solanum lycopersicum L); two species of wild tomato (Solanum habrochaites var hirsutum ‘PI-127826’ and Solanum pennellii ‘LA716’); other two tomato species [Solanum, cocona (Solanum sessiliflorum) and physalis (Physalis peruviana)] and a control with cultivar Santa Cruz Kada (auto-graft) rootstocks were used. In addition, two grafting methods were evaluated full cleft and approach graft. Fifteen days after grafting, plants were assessed for graft-take percentage; root length; plant height; leaf number; foliar area; root, stem and leaf dry matter; and ratio between shoot and root dry matter. Based on the results, we may state rootstock and grafting interaction had effect on both graft -take rate and plant development. Overall, the studied plants should be recommended as rootstock, except for 6889-50 mini-tomato (S. lycopersicum L.) and S. pennellii. Full cleft grafting was most suitable for cocona and physalis, while the approach method showed better results for the mini-tomato accessions 0224-53, RVTC 57 and RVTC 20, as well as for S. habrochaites.

https://doi.org/10.1590/1983-21252017v30n227rc 2443 downloads

Synthetic Analogue of the Natural Product Piperlongumine as a Potent Inhibitor of Breast Cancer Cell Line Migration
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Valli, Marilia

; Altei, Wanessa

; Santos, Ricardo N. dos

; Lucca Jr., Emilio C. de

; Dessoy, Marco A.

; Pioli, Renan M.

; Cotinguiba, Fernando

; Cachet, Xavier

; Michel, Sylvie

; Furlan, Maysa

; Dias, Luiz C.

; Andricopulo, Adriano D.

; Bolzani, Vanderlan S.

Journal of the Brazilian Chemical Society

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mar 2017, Volume 28 N. 3 Pages 475 - 484

Abstract: En | Text: En | PDF: En

Piperlongumine is a natural amide alkaloid isolated from several species of Piper and is described in the literature as selectively cytotoxic to several cancer cell lines. Inhibiting cell migration has gained considerable interest as an approach for discovering antimetastatic agents because this process is fundamental to metastasis. Piperlongumine, selected from cell-based assay screening of NuBBE Database, inhibited the migration of MDA-MB-231 breast cancer cells with an EC50 of 3.0 ± 1.0 µM by the Boyden chamber assay. A series of five analogous compounds based on the structure of piperlongumine were designed, synthesized and evaluated in cell migration and cytotoxicity assays. The analogue designed by molecular simplification ((E)-N-acryloyl-3-(3,4,5-trimethoxyphenyl)acrylamide) was the most active of the series, with an EC50 of 1.5 ± 1 µM. Additionally, this compound was selectively cytotoxic, with a selectivity index (SI) of 4.4.

https://doi.org/10.21577/0103-5053.20160303 1720 downloads

Ontogenetic variations and feeding habits of a Neotropical annual fish from southern Brazil
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Dias, Tatiana S.

; Stein, Ricardo J.

; Fialho, Clarice B.

Iheringia. Série Zoologia

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2017, Volume 107 elocation e2017020

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Conhecer a biologia alimentar de uma população e seus aspectos ontogenéticos podem auxiliar na compreensão do funcionamento de assembleias de peixes, fundamental para a conservação da biodiversidade do habitat no qual estas espécies são encontradas. Peixes anuais completam seu ciclo de vida em ambientes aquáticos temporários, sendo encontrados no estágio adulto somente em breves períodos anuais. Mudanças nos hábitos alimentares entre diferentes classes de tamanho podem indicar que uma espécie pertence a distintos grupos alimentares nas diferentes fases do crescimento. Este trabalho teve como objetivo caracterizar a dieta de Cynopoecilus fulgens Costa, 2002 em uma área temporariamente alagada na planície costeira sul-riograndense, levando em consideração possíveis alterações nos hábitos alimentares nas diferentes classes de tamanho corporal causadas por mudanças ontogenéticas, visando explicar a coexistência destes indivíduos em um curto espaço de tempo. A análise da dieta indica que C. fulgens é uma espécie generalista, ingerindo pequenos crustáceos e insetos autóctones. Diferenças intraespecíficas na composição da dieta foram verificadas quando comparadas entre as nove classes de comprimento padrão estabelecidas. Adultos se alimentaram principalmente de insetos autóctones, enquanto os juvenis ingeriram principalmente crustáceos, sendo a população separada em dois grupos tróficos: invertívoros e invertívoros com tendência à zooplanctivoria. É possível concluir que as mudanças ontogenéticas na dieta de C. fulgens estejam relacionadas a restrições morfológicas decorrentes do tamanho dos indivíduos, já que as relações competitivas, em termos alimentares, não são aparentemente tão evidentes.

ABSTRACT Knowing the feeding biology of a population and its ontogenetic aspects can help in understanding the functioning of fish assemblages, essential to the conservation of the habitat biodiversity in which these species are found. Annual fishes complete their life cycle in temporary aquatic environments, existing in adult stage only for brief annual periods. Changes in the feeding habits between different size classes could indicate that a species belongs to different feeding groups in different growth phases. The aim of this work was to characterize the diet of Cynopoecilus fulgens Costa, 2002 in a temporary flooded area in the coastal plain of southern Brazil, taking into consideration possible alterations in feeding habits in different body size classes caused by ontogenetic changes, to explain the coexistence of these individuals in a short space of time. The diet analysis indicated that C. fulgens is a generalist, consuming small crustaceans and autochthonous insects. Intraspecific differences in diet were determined when compared between nine classes of standard length. Adults fed mainly on autochthonous insects, and juveniles ingested mostly crustaceans, with the population being separated into two trophic groups: invertivores and invertivores with a tendency towards zooplanktivory. It is possible to conclude that the ontogenetic changes in the diet of C. fulgens are related to morphological restrictions due to the size of the individuals, since feeding competitive relations are probably not so evident.

https://doi.org/10.1590/1678-4766e2017020 2049 downloads

10.

Psychiatric and clinical correlates of rapid cycling bipolar disorder: a cross-sectional study
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Gigante, Alexandre D.

; Barenboim, Ivan Y.

; Dias, Rodrigo da S.

; Toniolo, Ricardo A.

; Mendonça, Tiago

; Miranda-Scippa, Ângela

; Kapczinski, Flávio

; Lafer, Beny

Brazilian Journal of Psychiatry

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dec 2016, Volume 38 N. 4 Pages 270 - 274

Abstract: En | Text: En | PDF: En

Objective: Rapid cycling (RC) is a feature of bipolar disorder (BD) that has been associated with worse outcome and more severe disability. Our goal was to investigate the association of demographic and clinical factors with RC. Methods: We compared RC and non-rapid cycling (NRC) BD patients from the Brazilian Research Network in Bipolar Disorder (BRN-BD) regarding age at onset of BD; total number of episodes; previous number of manic, depressive, mixed, and hypomanic episodes; polarity of the first episode; gender; number of suicide attempts; number of lifetime hospitalizations and lifetime history of at least one hospitalization; family history of mood disorder; clinical comorbidities such as hypothyroidism, hyperthyroidism, seizures; and current use of medications such as lithium, anticonvulsants, antipsychotics, and antidepressants. Results: We studied 577 patients and found that 100 (17.3%) met the criteria for RC in the year before the investigation. RC patients had earlier age at onset, longer duration of disease, more lifetime depressive and manic episodes, higher number of suicide attempts, and higher rate antidepressant use. Conclusion: The presence of RC in the previous year was associated with specific clinical characteristics closely related to worse outcome in the course of BD.

https://doi.org/10.1590/1516-4446-2015-1789 1773 downloads

11.

Eugenia uniflora Dentifrice for Treating Gingivitis in Children: Antibacterial Assay and Randomized Clinical Trial
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Jovito, Vanessa de Carvalho

; Freires, Irlan Almeida

; Ferreira, Danilo Augusto de Holanda

; Paulo, Marçal de Queiroz

; Castro, Ricardo Dias de

Brazilian Dental Journal

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aug 2016, Volume 27 N. 4 Pages 387 - 392

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Crianças em idade escolar apresentam, com frequência, alto risco para o desenvolvimento de doenças biofilme-dependentes, incluindo cárie e doenças periodontais. Este estudo investigou a eficácia clínica de um dentifrício contendo o extrato de Eugenia uniflora Linn. (pitanga) comparado a um dentifrício com triclosan no combate à gengivite em crianças de 10 a 12 anos. Foi avaliado o potencial antibacteriano in vitro do dentifrício sobre microorganismos da cavidade oral (S. mutans S. oralis and L. casei) e realizado um estudo clínico fase II incluindo 50 sujeitos, com sinais clínicos de gengivite, divididos aleatoriamente em dois grupos: Experimental - 25 sujeitos usaram o dentifrício contendo extrato de pitanga; e Controle - 25 sujeitos que usaram um dentifrício fluoretado contendo triclosan (Colgate Total 12(r)). Na baseline e após sete dias consecutivos de escovação, foi realizado o exame clínico para diagnóstico de gengivite (desfecho primário) e acúmulo de biofilme (desfecho secundário), utilizando o Índice de Sangramento Gengival (ISG) e Índice de Higiene Oral Simplificado (IHO-S). Os dados foram analisados utilizando o teste t pareado e não pareado (ISG) e teste de Wilcoxon e Mann-Whitney (IHO-S), com nível de significância de p≤0,05. Observou-se uma efetiva atividade antibacteriana do dentifrício experimental. No estudo clínico, observou-se redução de sangramento gengival em ambos os grupos experimental e controle (p<0,0001), não havendo diferença entre eles (p 0,178), embora com uma pequena magnitude de efeito. Apenas o grupo controle reduziu significantemente o acúmulo de biofilme (p=0,0039). Concluiu-se que o dentifrício experimental de E. uniflora mostrou-se eficaz na redução de gengivite em crianças de 10 a 12 anos. Assim, este dentifrício apresenta potencial para ser utilizado de forma eficaz e segura em odontologia preventiva.

Abstract School-age children are frequently at high risk for the onset of biofilm-dependent conditions, including dental caries and periodontal diseases. The objective of this study was to evaluate the clinical efficacy of a dentifrice containing Eugenia uniflora Linn. (Surinam cherry) extract versus a triclosan-based comparator in treating gingivitis in children aged 10-12 years. The in vitro antibacterial potential of the dentifrice was tested against oral pathogens (Streptococcus mutans, Streptococcus oralis and Lactobacillus casei). Then a phase-II clinical trial was conducted with 50 subjects aged 10-12 years, with clinical signs of gingivitis. The subjects were randomly assigned to the experimental group (n=25) and control group (n=25), in which participants used the experimental dentifrice and a triclosan-based fluoridated dentifrice (Colgate Total 12(r)), respectively. Clinical examinations assessed the presence of gingivitis (primary outcome) and biofilm accumulation (secondary outcome) using the Gingival-Bleeding Index (GBI) and Simplified Oral Hygiene Index (OHI-S), respectively, at baseline and after seven days of tooth brushing 3x/day. The data were analyzed using paired and unpaired t-test (GBI) and Wilcoxon and Mann-Whitney (OHI-S), with p≤0.05. The experimental dentifrice showed efficient antibacterial activity in vitro. In the clinical trial, a significant reduction in gingival bleeding was observed in both experimental and control groups (p<0.0001), with no statistical difference between them (p=0.178), although a small size effect was observed. Biofilm accumulation was only reduced in the control group (p=0.0039). In conclusion, E. uniflora dentifrice showed anti-gingivitis properties in children aged 10-12 years. Thus, it may be a potentially efficient and safe product to be used alternatively in preventive dental practice

https://doi.org/10.1590/0103-6440201600769 3057 downloads

12.

Nonlinear Equilibrium and Stability Analysis of Axially Loaded Piles Under Bilateral Contact Constraints
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Silveira, Ricardo A. da Mota

; Maciel, Felipe Vieira

; Silva, Andréa Regina Dias

; Machado, Fernando Carlos S.

; Nogueira, Christianne de Lyra

Latin American Journal of Solids and Structures

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apr 2015, Volume 12 N. 2 Pages 250 - 270

Abstract: En | Text: En | PDF: En

AbstractThis paper presents a nonlinear stability analysis of piles under bilateral contact constraints imposed by a geological medium (soil or rock). To solve this contact problem, the paper proposes a general numerical methodology, based on the finite element method (FEM). In this context, a geometrically nonlinear beam-column element is used to model the pile while the geological medium can be idealized as discrete (spring) or continuum (Winkler and Pasternak) foundation elements. Foundation elements are supposed to react under tension and compression, so during the deformation process the structural elements are subjected to bilateral contact constraints. The errors along the equilibrium paths are minimized and the convoluted nonlinear equilibrium paths are made traceable through the use of an updated Lagrangian formulation and a Newton-Raphson scheme working with the generalized displacement technique. The study offers stability analyses of three problems involving piles under bilateral contact constraints. The analyses show that in the evaluation of critical loads a great influence is wielded by the instability modes. Also, the structural system stiffness can be highly influenced by the representative model of the soil.

https://doi.org/10.1590/1679-78251173 2573 downloads

13.

Atividade antifúngica de produtos naturais indicados por raizeiros para tratamento de candidíase oral
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Freire Abílio, Vanessa Maria

; da Silva Mesquita, Bruno

; Darly da Silva, Evelyn

; Vilar de Queiroz Carvalho, Fabíola

; Aranha de Macêdo, Luciana Lucena

; Dias de Castro, Ricardo

Revista Cubana de Estomatología

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sep 2014, Volume 51 N. 3 Pages 259 - 269

Abstract: Pt En Es | Text: Pt En Es | PDF: Pt | PDF: En | PDF: Es

A crescente resistência das leveduras pertencentes ao gênero Candida frente aos antifúngicos sintéticos, atualmente disponíveis no comércio, impulsiona a busca por novos compostos antifúngicos de origem vegetal. Assim, o propósito do presente estudo foi avaliar in vitro a atividade antifúngica dos decoctos de Schinus terebenthifolius Raddi (aroeira) Cinnamomum zeylanicum Breym (canela) e Punica granatum Linn (romã), vendidos por raizeiros em três feiras livres distintas (A, B e C), frente a três espécies de microorganismos do gênero Candida (C. albicans, C. tropicalis e C. krusei). O ensaio para determinação da atividade antifúngica dos produtos naturais foi realizado pelo método da difusão em meio sólido, em triplicata, onde discos de papel de filtro estéreis embebidos em 50 µL dos extratos foram colocados sobre o meio de cultura. Os resultados foram avaliados a partir da mensuração dos diâmetros dos halos de inibição de crescimento fúngico em milímetros (mm), sendo considerada a moda dos valores obtidos. Foi observada atividade antifúngica de S. terebenthifolius Raddi e de C. zeylanicum Breym sobre C. krusei. No entanto, diferenças foram identificadas entre os produtos obtidos nos diferentes locais. O decocto de Punica granatum Linn apresentou atividade antifúngica sobre as três cepas fúngicas utilizadas no estudo. Também foram verificadas diferenças entres os produtos obtidos nas feiras livres, sendo que apenas as amostras de Punica granatum Linn provenientes da feira A foram capazes de inibir o crescimento fúngico de todas as cepas analisadas. Desta forma, conclui-se que todos os produtos avaliados apresentam atividade antifúngica, havendo diferenças relacionadas aos locais de sua obtenção e sensibilidade das cepas ensaiadas.

An increasing resistance of Candida yeasts to the synthetic antifungals currently available has driven the search for new plant-derived antifungal compounds. In this respect, the present study aimed to evaluate the in vitro antifungal activity of decoctions from Schinus terebenthifolius Raddi (Brazilian pepper tree), Cinnamomum zeylanicum Breym (cinnamon) and Punica granatum Linn (pomegranate) against three species of Candida genus (C. albicans, C. tropicalis and C. krusei). Such plant material was sold by herb sellers in three distinct street fairs (A, B and C). The test to determine the products antifungal activity was performed in triplicate by means of the diffusion method on solid medium, in which sterile filter paper discs were soaked in 50 µL of the extracts and then placed on culture medium. Data were assessed by measuring the diameters of halos of fungal growth inhibition, in millimeters (mm), and it was considered the mode of the values found. Antifungal activity of S. terebinthifolius Raddi and C. zeylanicum Breym was observed against C. krusei, but were identified differences among the products obtained in different locations. Punica granatum Linn decoction presented antifungal activity on the three yeasts under study. Also, were found differences among the products acquired in the street fairs, but only the samples of Punica granatum Linn from fair A were able to inhibit fungal growth of all yeasts analyzed. Thus, it is concluded that all the products assessed showed antifungal activity, but differences were found depending on the location where these were obtained and on the sensitivity to the strains assayed.

La resistencia cada vez mayor de levaduras del género candida a los antifúngicos sintéticos disponibles en la actualidad ha llevado a la búsqueda de nuevos compuestos antifúngicos de origen vegetal. El propósito de este estudio fue evaluar la actividad antifúngica in vitro de decocciones de Schinus terebenthifolius Raddi (pimentero brasileño),Cinnamomum zeylanicum Breym (canela) y Punica granatum Linn (granada) sobre tres especies del género Candida (C. albicans, C . tropicalis y C. krusei). Este material vegetal fue vendido por vendedores de hierbas (raizeiros) en tres ferias callejeras distintas (A, B y C). El ensayo para determinar la actividad antifúngica de los productos se realizó por triplicado. Se empleó el método de difusión en medio sólido, en el que discos de papel de filtro estériles fueron empapados en 50 µL de los extractos y colocados en medio de cultivo. Los datos fueron evaluados mediante la medición de los diámetros de los halos de inhibición del crecimiento fúngico, en milímetros, y se consideró la moda de los valores encontrados. Se observó actividad antifúngica de S. terebinthifolius Raddi y C. zeylanicum Breym contra C. krusei, pero fueron identificadas diferencias entre los productos obtenidos en diferentes lugares. La decocción de Punica granatum Linn presentó actividad antifúngica sobre las tres levaduras en estudio. Además, se encontraron diferencias entre los productos adquiridos en las ferias callejeras, pero sólo las muestras de Punica granatum Linn de la feria A fueron capaces de inhibir el crecimiento de hongos de todas las levaduras analizadas. Todos los productos evaluados mostraron actividad antifúngica, pero hubo diferencias en función de la localidad donde los productos fueron obtenidos y de la sensibilidad a las cepas ensayadas.

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14.

Manejos da fertirrigação e doses de N e K no cultivo de pimentão em ambiente protegido
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Oliveira, Francisco de A. de

; Duarte, Sérgio N.

; Medeiros, José F. de

; Dias, Nildo da S.

; Silva, Ricardo C. P. da

; Lima, Carlos J. G. de S.

Revista Brasileira de Engenharia Agrícola e Ambiental

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nov 2013, Volume 17 N. 11 Pages 1152 - 1159

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Este trabalho foi desenvolvido com o objetivo de se avaliar os efeitos de manejos de fertirrigação e níveis de nitrogênio e potássio sobre o crescimento e a produção de pimentão cultivado em ambiente protegido. Utilizou-se o delineamento em blocos casualizados com 18 tratamentos e quatro repetições. Os tratamentos resultaram da combinação de três manejos da fertirrigação e com seis doses de nitrogênio e potássio. Foram realizadas seis colheitas e, nelas, avaliações quanto ao número, massa média e produção de frutos além de indicadores de crescimento (área foliar, altura e acúmulo de fitomassa). Os resultados obtidos demonstram que o crescimento e o rendimento do pimentão dependem, além das doses de N e K, do manejo de fertirrigação adotado. O manejo da fertirrigação a partir do monitoramento da concentração de íons de N e K com auxílio dos extratores de solução, ou da condutividade elétrica da solução do solo é mais eficiente que o manejo tradicional. O monitoramento da solução do solo deve ser realizado utilizando-se, como referência, as concentrações variando de 200 e 250% de N e K correspondentes à recomendação para a cultura do pimentão em sistema hidropônico.

This study was carried out for evaluating the effects of fertigation management and levels of nitrogen and potassium on growth and yield of bell pepper in protected environment. The experimental design was in a completely randomized block, with 18 treatments and four replications. Treatments resulted from the combination of three fertigation managements and six nitrogen and potassium doses. There were six harvests, when evaluations were made of fruit number, mean mass and yield, as well as of growth indicators (leaf area, plant height and dry mass). Results showed that, besides the N and K doses, bell pepper growth and yield also depend on the management of fertigation used. Fertigation managements based on concentration of N and K ions using solution extractors, and monitoring of soil electrical conductivity were better than the usual management. Soil solution monitoring must take as reference N and K concentrations between 200 and 250% of recommendation for bell pepper production in hydroponic system.

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15.

Análise de detecção de cluster na caracterização espaço-temporal da tuberculose bovina no estado da Bahia
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Ávila, Luciana N.

; Perez, Andrés M.

; Ferreira Neto, José S.

; Ferreira, Fernando

; Telles, Evelise O.

; Dias, Ricardo A.

; Amaku, Marcos

; Gonçalves, Vitor S.P.

Pesquisa Veterinária Brasileira

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nov 2013, Volume 33 N. 11 Pages 1313 - 1318

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

A tuberculose bovina (BTB) é uma enfermidade causada pela infecção pelo Mycobacterium bovis que acomete o homem e diversas espécies de mamíferos. A BTB tem grande importância por causar prejuízos econômicos nas regiões infectadas e por seu impacto na saúde pública. Foi realizado inquérito epidemiológico no Estado da Bahia, entre 2008 e 2010, com o objetivo de estimar a prevalência e conhecer a distribuição espaço temporal da enfermidade. O Estado foi estratificado em quatro regiões, cada uma com características epidemiológicas e demográficas homogêneas representativas de formas de produção pecuária. Um total de 18.810 cabeças com idade superior a 2 anos foi amostrado em 1350 propriedades. O teste cervical comparativo foi aplicado em cada animal selecionado, sendo considerados positivos os animais reagentes positivos ou duas vezes inconclusivos. Latitude e Longitude foram tomadas para cada propriedade amostrada com o auxilio do aparelho de Global Positioning System (GPS). O teste de Cuzick-and-Edwards e a análise de rastreio espacial (spatial scan statistic) foram utilizados para identificar qualquer agrupamento espacial de BTB. A prevalência de rebanho na Bahia, indicando a proporção de propriedades foco, foi de 1,6% (IC 95%: 1,0% - 2,69% por região). Nenhuma evidência significativa (P<0.05) de aglomeração espacial ou clustering foi detectada, possivelmente devido à baixa prevalência da doença. Estes resultados sugerem que a BTB tem baixa prevalência no estado da Bahia e que, nestas condições epidemiológicas, os focos encontrados não podem ser explicados por fatores espacialmente estruturados.

Bovine tuberculosis (BTB) is a disease caused by the infection with Mycobacterium bovis that affects humans and several mammalian species. BTB is important, because it inflicts far-reaching economic losses to infected regions, and due to its impact on public health. Epidemiological surveys were conducted in the State of Bahia between 2008 and 2010 with the objective to estimate the prevalence and to assess the spatial distribution of the disease. The State of Bahia has been stratified into four regions, each of them representing a set of homogeneous epidemiological and demographic characteristics, referred to as Production Circuits. A total of 18,810 more than 2-year-old cattle in 1,305 herds, ranging from 320 to 370 ones per region, and 20 to 40 cattle per herd were randomly selected. A cervical comparative test was applied to each selected animal; reactive cattle and cattle with two consecutive inconclusive tests were considered BTB-positive, whereas non-reactive cattle were considered BTB-negative. Positive herds were classified as those with <20 sampled cattle and at least one BTB-positive, as well as those with 40 cattle sampled with <2 BTB-positive animals. Latitude and longitude were recorded for each sampled herd with a generic Global Positioning System (GPS). The Cuzick-and-Edwards' test and the spatial scan statistic were used to assess whether BTB was spatially clustered. Herd-level prevalence, as indicated by the proportion of case-herds, was 1.6% (range 0.3 to 2.9% per region). No significant evidence (P<0.05) of spatial clustering was detected, most likely due to the low disease prevalence in the region. Results here suggest that BTB is low prevalent in the State of Bahia and that under these conditions epidemiological outbreaks found cannot be explained by spatially-structured factors.

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