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Estudio bacteriológico, serológico e histopatológico de lechones destetados infectados experimentalmente con Salmonella Typhimurium
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Joaquim, P.

; Balbiani, F.

; Delgado, F.

; Redondo, L.

; Cappuccio, J.

; Chacana, P.

Revista veterinaria

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oct 2023, Volume 34 N. 2 Pages 81 - 90

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

Abstract 19. In the last decades, infections by several serovars of Salmonella have become relevant worldwide, not only due to their impact on veterinary health and animal production, but also because they may serve as a source of infection for the human population. Pigs can be infected by several Salmonella serovars, being S. Typhimurium one of the most frequently isolated worldwide. In this context, the evaluation of strategies to control Salmonella in farms demands the understanding of the pathogenesis of the microorganism. Thus, the objective of this work was to carry out an experimental infection in 50-day-old pigs using a field strain of S. Typhimurium to evaluate the excretion of the microorganism, organs colonization and the development of histological injuries over the 13-day trial period. Disease was successfully reproduced in eight animals, and two clinical patterns were identified. In four animals, a primarily enteric pattern was observed, where the infection was limited to the gastrointestinal tract, while in another four pigs, enteric and systemic infection with variable fecal excretion and invasion of internal organs was observed. These two infectious patterns were accompanied by changes in fecal consistency and reduced daily weight gain or weight loss in the animals. The observation of two different infectious patterns highlights the need to consider the complexity of the pathogenicity of Salmonella Typhimurium infection in pigs.

Resumen. 23. En las últimas décadas las infecciones por diferentes serovariedades de Salmonella han adquirido importancia a nivel mundial, no solo por su impacto en la sanidad y en la producción de los animales, sino también porque estos constituyen una fuente de infección para los humanos. Los cerdos pueden estar infectados o ser portadores de distintas serovariedades con potencial zoonótico, siendo S. Typhimurium una de las más frecuentemente aisladas a nivel mundial. En este contexto, la evaluación de estrategias para el control de Salmonella en granjas exige el conocimiento de la patogenia del microorganismo. El objetivo de este trabajo fue realizar una infección experimental en cerdos de 50 días de edad utilizando una cepa de campo de S. Typhimurium para evaluar la excreción del microorganismo, la colonización de órganos y el desarrollo de lesiones histológicas durante los 13 días del ensayo. Se logró reproducir la enfermedad en ocho animales y se pudo identificar dos cuadros clínicos. En cuatro animales se observó un cuadro principalmente entérico, en el que la infección estuvo limitada al tracto gastrointestinal; mientras que en otros cuatro cerdos se observó infección entérica y sistémica con excreción fecal variable e invasión de órganos internos. Estos dos cuadros infecciosos estuvieron acompañados de cambios en la consistencia de la materia fecal y menor ganancia diaria de peso o adelgazamiento de los animales. La observación de dos cuadros infecciosos diferentes muestra la necesidad de considerar la complejidad de la patogenicidad de la infección por Salmonella Typhimurium en cerdos.

https://doi.org/10.30972/vet.3427048

Evaluación de la capacidad de reventado de genotipos de amaranto y parámetros genéticos
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Espitia-Rangel, Eduardo

; Lozano-Grande, Azalia

; Aguilar-Delgado, Miriam J.

; Valverde-Ramos, Miriam G.

; González-Molina, Lucila

; Martínez-Cruz, Eliel

Revista mexicana de ciencias agrícolas

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sep 2023, Volume 14 N. 6 elocation e3429

Abstract: Es En | Text: Es En | PDF: Es | PDF: En

Resumen Actualmente existe el interés a nivel mundial por aprovechar las características agronómicas y nutritivas de super alimentos como el amaranto, en México se consume reventado por lo que es importante dilucidar los factores que influyen en esta capacidad para su mejor aprovechamiento. Por lo que el objetivo fue evaluar la capacidad de reventado de 12 genotipos de amaranto, la variabilidad genética, heredabilidad y la asociación de variables de calidad industrial con el volumen de reventado. El experimento se desarrolló en las localidades de Santa Lucía de Prías y Boyeros, Estado de México y Cuapiaxtla, Tlaxcala en los años 2019 y 2020. El genotipo más destacado en volumen de reventado fue Tlahuicole, seguido por AGIM ambos tuvieron el mayor incremento (6 y 5.93) respectivamente. Se observó que la variación debida a efectos ambientales fue la principal fuente en 4 de las 5 variables estudiadas, tal variación no es capitalizable en esquemas de selección; por otro lado, peso de mil granos fue la variable que presentó la variación más alta debida a efectos genéticos (65.96%), la cual es capitalizable en un esquema de selección. Las variables diámetro de semilla, volumen de reventado e incremento de volumen, presentaron una variación debida a efectos genéticos entre 4.46 y 6.5%, si se quiere iniciar un esquema de selección se deberá incluir germoplasma con mayor variabilidad en estos caracteres. La asociación significativa entre diámetro de semilla y peso semilla sin reventar indica que estos caracteres que pueden utilizarse como criterios de selección el volumen de reventado.

Abstract Currently, there is worldwide interest in taking advantage of the agronomic and nutritional characteristics of superfoods such as amaranth, in Mexico it is consumed popped so it is important to elucidate the factors that influence this capacity for its better use. Therefore, the objective was to evaluate the popping capacity of 12 amaranth genotypes, genetic variability, heritability and the association of industrial quality variables with the popping volume. The experiment was conducted in the localities of Santa Lucía de Prías and Boyeros, State of Mexico and Cuapiaxtla, Tlaxcala in the years 2019 and 2020. The most outstanding genotype in popping volume was Tlahuicole, followed by AGIM, both had the largest increase (6 and 5.93), respectively. It was observed that the variation due to environmental effects was the main source in 4 of the 5 variables studied, such variation is not capitalizable in selection schemes; on the other hand, weight of one thousand grains was the variable that showed the highest variation due to genetic effects (65.96%), which is capitalizable in a selection scheme. The variables seed diameter, popping volume and volume increase presented a variation due to genetic effects between 4.46 and 6.5%, if there is intention to start a selection scheme, germplasm with greater variability in these traits must be included. The significant association between seed diameter and weight of non-popped seed indicates that these traits can be used as selection criteria for popping volume.

https://doi.org/10.29312/remexca.v14i6.3429

Can We Identify the Theorem in Metaphysics 9, 1051a24-27 with Euclid’s Proposition 32? Geometric Deductions for the Discovery of Mathematical Knowledge
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Ortiz Delgado, Francisco Miguel

Tópicos (México)

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aug 2023, N. 66 Pages 41 - 65

Abstract: Es En | Text: Es En | PDF: Es | PDF: En

Resumen. El presente artículo posee dos objetivos concretos. Primero, demostrar que el teorema que se encuentra en Metafísica Θ 9, 1051a24-27, no es equivalente a la Proposición 32 de Euclides (contradiciendo a algunos comentaristas de Aristóteles, como W. D. Ross, J. L. Heiberg y T. L. Heith). Coincidiendo con el análisis de Henry Mendell, defiendo que los dos teoremas no son equivalentes; sin embargo, ofrezco diferentes razones para dicha divergencia: propongo una razón pedagógicofilosófica para que el teorema aristotélico sea más corto que el de Euclides (y que versiones previas del propio Aristóteles). El Estagirita desea enfatizar al procedimiento deductivo como un método satisfactorio para descubrir conocimientos científicos. El segundo objetivo, que se opone a un cierto consenso existente sobre las deducciones geométricas en Aristóteles, es proponer brevemente que el teorema, tal y como lo encontramos en la Metafísica y sin necesidad de ninguna enmienda al texto (oponiéndome a las enmiendas sugeridas por Henry Mendell), permite a Aristóteles demostrar que el conocimiento matemático universal está en potencia en las figuras geométricas. Esta propuesta tentativamente prueba que Aristóteles enfatiza que la deducción geométrica es suficiente para actualizar al conocimiento matemático.

Abstract. This paper has two specific goals. The first is to demonstrate that the theorem in Metaphysics Θ 9, 1051a24-27 is not equivalent to Euclid’s Proposition 32 of book I (which contradicts some Aristotelian commentators, such as W. D. Ross, J. L. Heiberg, and T. L. Heith). Agreeing with Henry Mendell’s analysis, I argue that the two theorems are not equivalent, but I offer different reasons for such divergence: I propose a pedagogical-philosophical reason for the Aristotelian theorem being shorter than the Euclidean one (and the previous Aristotelian versions). Aristotle wants to emphasize the deductive procedure as a satisfactory method to discover scientific knowledge. The second objective, opposing some consensus about geometrical deductions/theorems in Aristotle, is to briefly propose that the theorem, exactly as we found it in Metaphysics and without any emendation to the text (therefore opposing Henry Mendell’s suggested amendments), allows the ancient philosopher to demonstrate that universal mathematical knowledge is in potence in geometrical figures. This tentatively proves that Aristotle emphasizes that geometrical deduction is sufficient to actualize mathematical knowledge.

https://doi.org/10.21555/top.v660.2155

Comorbidity patterns and mortality among hospitalized patients with psychiatric disorders and COVID-19
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Sánchez-Rico, Marina

; Rezaei, Katayoun

; Delgado-Álvarez, Alfonso

; Limosin, Frédéric

; Hoertel, Nicolas

; Alvarado, Jesús M.

Brazilian Journal of Psychiatry

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aug 2023, Volume 45 N. 4 Pages 327 - 333

Abstract: En | Text: En | PDF: En

Objectives: To examine the association between psychiatric and non-psychiatric comorbidity and 28-day mortality among patients with psychiatric disorders and COVID-19. Methods: Multicenter observational retrospective cohort study of adult patients with psychiatric disorders hospitalized with laboratory-confirmed COVID-19 at 36 Greater Paris university hospitals (January 2020-May 2021) (n=3,768). First, we searched for different subgroups of patients according to their psychiatric and non-psychiatric comorbidities through cluster analysis. Next, we compared 28-day all-cause mortality rates across the identified clusters, while taking into account sex, age, and the number of medical conditions. Results: We found five clusters of patients with distinct psychiatric and non-psychiatric comorbidity patterns. Twenty-eight-day mortality in the cluster of patients with mood disorders was significantly lower than in other clusters. There were no significant differences in mortality across other clusters. Conclusion: All psychiatric and non-psychiatric conditions may be associated with increased mortality in patients with psychiatric disorders and COVID-19. The lower risk of death among patients with mood disorders might be in line with the potential beneficial effect of certain antidepressants in COVID-19, but requires further research. These findings may help identify at-risk patients with psychiatric disorders who should benefit from vaccine booster prioritization and other prevention measures.

https://doi.org/10.47626/1516-4446-2023-3076

Efficacy of ClinproTMXT Varnish surrounding brackets on the enamel surface of white spot lesion.
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Bergamo, Ana Zilda Nazar

; Miguel, Lucas Portilho

; Delgado, Renata Zoraida Rizental

; Palma-Dibb, Regina Guenka

; Faraoni, Juliana Jendiroba

; Gatón-Hernández, Patricia

; Silva, Raquel Assed Bezerra da

; Silva, Léa Assed Bezerra da

; Nelson-Filho, Paulo

Brazilian Dental Journal

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aug 2023, Volume 34 N. 4 Pages 143 - 149

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

Abstract Orthodontics patients usual develop demineralization and present cavity caries lesions after six months. Minimally invasive procedures have been the goal in modern dental practice. The aim of this study was to evaluate the effect of ClinproTMXT Varnish, on the enamel surface roughness and severity of white spot lesions. Twenty premolars were submitted to bond brackets and experimental induction of demineralization and randomly divided into 2 groups: GI - fluoride varnish (Colgate Duraphat®); GII - Ionomeric Sealant (ClinproTMXT Varnish). The treatment was applied around the brackets. The surface roughness of specimens was analyzed, before treatment and 12 weeks after treatment by laser confocal microscopy, and the severity of the white spot lesion was by laser fluorescence device. The data were analyzed by non-parametric Wilcoxon and Mann-Whitney Test, at 5% significance, roughness percentage reduction was performed. The severity of demineralization decreased in both, GI (p = 0.005) and GII (p = 0.019). Enamel superficial roughness levels decreased in GI and GII. As well as the roughness percentage, being more expressive in the ClinproTMXT Varnish group (85,09%). Colgate Duraphat® or Clinpro™ XT Varnish reduced the severity of the demineralization and decreased the superficial roughness on the enamel. The Clinpro™ XT Varnish was superior to superficial roughness on enamel.

Resumo Pacientes ortodônticos geralmente desenvolvem desmineralização e apresentam lesões de cárie após seis meses de tratamento. Procedimentos minimamente invasivos têm sido o objetivo na prática odontológica moderna. O objetivo deste estudo foi avaliar o efeito do ClinproTM XT selante ionomérico, ao redor do bráquete, com relação a rugosidade superficial do esmalte e a severidade da lesão induzida. Vinte pré-molares foram submetidos a colagem de bráquetes e indução experimental de desmineralização e divididos aleatoriamente em 2 grupos: GI - verniz fluoretado (Colgate Duraphat®); GII - Selante Ionomérico (ClinproTM XT). O tratamento foi aplicado ao redor dos bráquetes. A rugosidade da superfície dos espécimes foi analisada, antes do tratamento e 12 semanas após o tratamento por microscopia confocal a laser e severidade da lesão de mancha branca por dispositivo de fluorescência a laser. Os dados foram analisados pelo teste não paramétrico de Wilcoxon e Mann-Whitney, a 5% de significância. A taxa de redução da lesão foi calculada. A severidade da desmineralização diminuiu tanto no GI (p = 0,005) quanto no GII (p = 0,019). Os níveis de rugosidade superficial do esmalte diminuíram no GI e GII, assim como o percentual de rugosidade, sendo mais expressivo no grupo ClinproTMXT (85,09%). Colgate Duraphat® e Clinpro™ XT reduziram a severidade da desmineralização e diminuíram a rugosidade superficial do esmalte. O selante ionomérico Clinpro™ XT foi superior na redução percentual de rugosidade.

https://doi.org/10.1590/0103-6440202305405

Micropropagación y conservación de germoplasma de Ficus americana Aubl. y F. obtusifolia Kunth de Lambayeque (Perú)
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Delgado-Paredes, Guillermo E.

; Rojas-Idrogo, Consuelo

; Esquerre-Ibañez, Boris

; Vásquez-Díaz, Cecilia

; Zuñe-Da Silva, Felipe

; Kuethe, J. R.

Colombia Forestal

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jun 2023, Volume 26 N. 1 Pages 92 - 108

Abstract: Es En | Text: Es En | PDF: Es | PDF: En

Resumen Ficus americana y F. obtusifolia, se encuentran entre las especies arbóreas más importantes de los Bosques Tropicales Estacionalmente Secos (BTES) por su condición de siempre verdes y sus altos niveles de biomasa. Sin embargo, el BTES de Lambayeque y el norte de Perú está disminuyendo enormemente debido al avance de la agricultura migratoria, la minería ilegal y la deforestación. El objetivo de este trabajo fue estudiar los aspectos taxonómicos de ambas especies, así como la germinación de semillas, la micropropagación y la conservación de germoplasma in vitro. La germinación de semillas fue de 100 % en ambas especies hasta tres meses después de la recolección. Respecto a la micropropagación, el enraizamiento y la conservación de germoplasma, el medio de cultivo de Piper resultó efectivo, el cual está conformado por sales minerales MS con IAA 0.02 mg.L-1 y GA3 0.02 mg.L-1. La conservación in vitro de germoplasma duró más de 24 meses en ambas especies. La aclimatación en condiciones de invernadero alcanzó 50 % de supervivencia en ambas especies.

Abstract Ficus americana and F. obtusifolia are among the most important tree species in Seasonally Dry Tropical Forests (SDTF) due to their evergreen condition and high levels of biomass. However, the SDTF of Lambayeque and northern Peru is greatly diminishing due to the advance of migratory agriculture, illegal mining, and deforestation. The objective of this work was to study the taxonomic aspects of both species, as well as seed germination, micropropagation, and in vitro germplasm conservation. Seed germination was 100% for both species up to three months after collection. As for micropropagation, rooting, and germplasm conservation, the Piper culture medium was effective, as it was constituted by MS mineral salts with 0.02 mg.L-1 IAA and 0.02 mg.L-1 GA3. In vitro germplasm conservation lasted more than 24 months for both species. Acclimatization under greenhouse conditions reached 50% survival for both species.

https://doi.org/10.14483/2256201x.19114

Relationship between body weight and scrotal circumference in growing Pelibuey sheep raised under tropical conditions
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Ramírez-Bautista, M.A.

; Cruz-Tamayo, A.A.

; Gastélum-Delgado, M.Á.

; Aguilar-Quiñónez, J.A.

; Tyasi, T.L.

; Gurgel, A.L.C.

; García-Herrera, R.A.

; Chay-Canul, A. J.

Arquivo Brasileiro de Medicina Veterinária e Zootecnia

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jun 2023, Volume 75 N. 3 Pages 519 - 524

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

ABSTRACT The body weight (BW) of an animal is a vital economic trait that might help in decision-making in the handling of animals. The objective of the present study was to develop equations for the prediction of BW in Pelibuey sheep using scrotal circumference (SC). The BW (23.40 ± 6.96 kg) and SC (20.25 ± 6.19 cm) have been recorded in 405 male Pelibuey at the Southeastern Center for Ovine Integration, Mexico. Linear, logarithmic, quadratic, exponential, cubic, and power regression models were used for data analysis. Pearson correlation (R), Coefficient of determination (R2), Adjusted coefficient of determination (Adj.R2) Root mean square error (RMSE), Akaike information criterion (AIC), and Bayesian information criterion (BIC) were used to select the best model. Power regression model showed the highest R (0.93), R2 (0.86), Adj.R2 (0.86) and lowest RMSE (0.02), AIC (-989.44) and BIC (-981.44). The current study suggests that SC might be used as the only predictor for BW of growing Pelibuey sheep raised under tropical conditions.

RESUMO O peso corporal (PC) do animal é uma característica econômica importante, que pode auxiliar na tomada de decisões no manejo dos animais. O objetivo do presente estudo foi desenvolver equações para a predição do PC em ovinos Pelibuey por meio da circunferência escrotal (CE). O PC (23,40±6,96kg) e a CE (20,25±6,19cm) foram registrados em 405 ovinos machos da raça Pelibuey no Centro de Integração Ovina da Região Sudeste do México. Os modelos lineares, logarítmicos, quadráticos, exponenciais, cúbicos e de regressão de potência foram utilizados para a análise dos dados. A correlação de Pearson (R), o coeficiente de determinação (R2), o coeficiente de determinação ajustado (Adj.R2), o erro do quadrado médio (EQM), o critério de informação de Akaike (AIC) e o critério de informação bayesiano (BIC) foram usados para selecionar o melhor modelo. O modelo de regressão de potência apresentou maiores R (0,93), R2 (0,86), Adj.R2 (0,86) e menores EQM (0,02), AIC (-989,44) e BIC (-981,44). O estudo atual sugere que a CE pode ser usada como um único preditor para o PC de ovinos Pelibuey em crescimento criadas em condições tropicais.

https://doi.org/10.1590/1678-4162-12902

Endoscopic Release of the Ulnar Nerve at the Elbow: Technique Description and Case Series
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Oliveira, Ricardo Kaempf de

; Brunelli, João Pedro Farina

; Araújo, Matheus Baldasso

; Aita, Márcio

; Carratalá, Vicente

; Delgado, Pedro J.

Revista Brasileira de Ortopedia

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may 2023, Volume 58 N. 3 Pages 449 - 456

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

Abstract Objective The endoscopic release of the ulnar nerve reproduces a simple (in situ) procedure with smaller incisions, less soft tissue damage, and higher preservation of nerve vascularization. Endoscopy allows the clear visualization of the entire path of the nerve and surrounding noble structures. Moreover, it reveals any signs of compression and allows a safe release of 10cm distally or proximally to the medial epicondyle. Methods A retrospective survey revealed that 15 subjects (1 with a bilateral injury) underwent an ulnar nerve compression release at the elbow using the endoscopic technique with Agee (Micro-Aire Sugical Instruments, Charlottesville, VA, EUA) equipment from January 2016 to January 2020. Results Symptoms of ulnar nerve compression improved in all patients; on average, they resumed their work activities in 26.5 days. There was no recurrence or need for another procedure. In addition, there were no severe procedure-related complications, such as infection and nerve or vascular injury. One patient had transient paresthesia of the sensory branches to the forearm, with complete functional recovery in 8 weeks. Conclusion Our study shows that the endoscopic release of the ulnar nerve at the elbow with the Agee equipment is a safe, reliable technique with good outcomes.

Resumo Objetivo A liberação endoscópica do nervo ulnar permite reproduzir uma liberação simples (in situ), mas através de incisões menores e com menor lesão de partes moles e uma maior preservação da vascularização do nervo. A visualização clara através da endoscopia permite observar todo o trajeto do nervo e das estruturas nobres circundantes, mostrando os sinais de compressão, possibilitando realizar a liberação de forma segura em um trajeto de 10 cm nos sentidos distal e proximal ao epicôndilo medial. Método Foram encontrados, de forma retrospectiva, no período entre janeiro de 2016 e janeiro de 2020, 15 pacientes (sendo 1 com lesão bilateral) submetidos a liberação da compressão do nervo ulnar no cotovelo pela técnica endoscópica com equipamento de Agee (Micro-Aire Sugical Instruments, Charlottesville, VA, EUA). Resultados Todos os pacientes tiveram melhora dos sintomas de compressão do nervo ulnar e o período de retorno ao trabalho foi de em média 26,5 dias. Não houve recidivas e não houve a necessidade de outro procedimento. Também não houve complicações graves decorrentes do procedimento, como infecção, lesão nervosa ou vascular. Em um paciente, houve parestesia transitória dos ramos sensitivos para o antebraço, com retorno completo da função em 8 semanas. Conclusão Os resultados mostram que a liberação endoscópica do nervo ulnar no cotovelo comoequipamentodeAgeeéuma técnica segura, confiável e com bons resultados.

https://doi.org/10.1055/s-0042-1751023

Secondary metabolites in Viguiera (Compositae, Heliantheae, Helianthinae) and segregated genera. A review of their biological activities with chemotaxonomic observations
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Arciniegas, Amira

; Pérez-Castorena, Ana-L.

; Romo de Vivar, Alfonso

; Gaona-Gaona, Leobardo

; Espinosa-García, Francisco J.

; Villaseñor, José Luis

; Delgado, Guillermo

Botanical Sciences

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mar 2023, Volume 101 N. 1 Pages 1 - 40

Abstract: Es En | Text: Es En | PDF: Es | PDF: En

Resumen Antecedentes. La primera monografía del género Viguiera fue publicada en 1918 por Blake, incluyendo alrededor de 141 especies. Schilling & Panero en sus estudios sobre la Subtribu Helianthinae (Tribu Heliantheae) basados en secuencias moleculares de los Espaciadores nucleares Transcritos Interno y Externos, así como de cpDNA, proponen reclasificar al género reubicando sus especies en al menos otros nueve géneros. Pregunta: ¿Es posible identificar patrones distintivos entre las especies de la nueva clasificación de Viguiera s. l. y los resultados obtenidos de los estudios químicos reportados? Especies consideradas: Sesenta y siete especies en la circunscripción amplia de Viguiera con estudios químicos y actividades biológicas informados. Resultados: Las especies del género Viguiera s.l. sintetizan terpenoides, representados principalmente por lactonas sesquiterpénicas y diterpenos, aunque también se reportan triterpenos, poliacetilenos, terpenoides volátiles y flavonoides. En todas las especies estudiadas se obtuvieron los principales tipos de metabolitos, siendo algunos más frecuentes que otros en ciertos clados. Conclusión: Los principales constituyentes del género Viguiera s l. son germacrólidas, heliangólidas, furanoheliangólidas, diterpenos tetracíclicos y flavonoides. Se notan algunas relaciones quimiotaxonómicas interesantes. No obstante, no se observaron patrones distintivos claros entre los clados y grupos químicos de los géneros segregados. Estos resultados son probablemente consecuencia de la diversidad de objetivos y metodologías de los estudios químicos reportados.

Abstract Background: The first monograph of the genus Viguiera was published in 1918 by Blake, including about 141 species. Schilling & Panero based on studies of molecular sequences of nuclear Internal Transcribed Spacer and External Transcribed Spacer, as well as cpDNA, proposed to reclassify the genus, relocating its species in at least other nine genera. Question: Is it possible to identify distinctive patterns between the species of the new classification of Viguiera s. l. and the results of the chemical studies reported? Species considered: Sixty-seven species within the wide Viguiera circumscription with chemical studies and biological activities reported. Results: The species of the genus Viguiera synthesize terpenoids represented mainly by sesquiterpene lactones and diterpenes, with triterpenes, polyacetylenes, volatile terpenoids and flavonoids also present. The main types of secondary metabolites were present in the studied species, although some compounds were more frequent than others in some clades. Conclusion: Germacrolides, heliangolides, furanoheliangolides, tetracyclic diterpenes and flavonoids are the main constituents of Viguiera and segregated genera. Some interesting chemotaxonomic relationships are noted. Nevertheless, nondistinctive clear patterns were observed between clades and chemical groups. These results are likely a consequence of the diversity of objectives and methodologies of the reported chemical studies on Viguiera.

https://doi.org/10.17129/botsci.3072

10.

Web-tools for the genomic analysis of the 2022 Monkeypox virus global outbreak.
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Moros, Zoila C.

; Loureiro, Carmen L.

; Jaspe, Rossana C.

; Sulbarán, Yoneira

; Delgado, Mariangel

; Aristimuño, Olga Carolina

; Franco, Christopher

; Garzaro, Domingo J.

; Rodríguez, Mariajosé

; Rangel, Héctor R.

; Liprandi, Ferdinando

; Pujol, Flor H.

; Zambrano, José Luis

Investigación Clínica

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mar 2023, Volume 64 N. 1 Pages 68 - 80

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

Abstract The resources and platforms available on the internet for collecting and sharing information and performing genomic sequence analysis have made it possible to follow closely the evolution the evolution of SARS-CoV-2. However, the current monkeypox outbreak in the world brings us back to the need to use these resources to appraise the extent of this outbreak. The objective of this work was an analysis of the information presented so far in the genomic database GISAID EpiPox™, using various tools available on the web. The results indicate that the monkeypox outbreak is referred as MPXV clade II B.1 lineage and sub-lineages, isolated from male patients mainly from the European and American continents. In the current scenario, the access to genomic sequences, epidemiological information, and tools available to the scientific community is of great importance for global public health in order to follow the evolution of pathogens.

Resumen Los recursos y plataformas disponibles en Internet para recopilar, compartir información y realizar análisis de secuencias genómicas han permitido seguir de cerca la evolución del SARS-CoV-2. El actual brote global de viruela del mono en el mundo, requiere de nuevo utilizar estos recursos para conocer el alcance de este brote. El objetivo de este trabajo fue un análisis de la información presentada hasta el momento en la base de datos genómica EpiPox™ de GISAID, utilizando diversas herramientas disponibles en la web. Los resultados indican que el brote de la viruela del mono o símica está referido al linaje y sub-linajes B.1 del clado II de MPXV, aislado principalmente de pacientes hombres de Europa y América. En el escenario actual, el acceso a las secuencias genómicas, la información epidemiológica, y las herramientas disponibles para la comunidad científica son de gran importancia para la salud pública mundial con el fin de seguir la evolución de los patógenos.

https://doi.org/10.54817/ic.v64n1a06

11.

Afrontamiento al estrés como predictor del Crecimiento Postraumático en una población peruana durante la COVID-19
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Delgado Requejo, Neicer J.

; Cerda Sánchez, Lourdes C.

; Castillo Ramos, Julio C.

Revista de Investigación en Psicología

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jan 2023, Volume 26 N. 1 Pages 61 - 76

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

ABSTRACT Background . The Peruvian population during Covid-19 has been exposed to stressful and traumatic events, associated with close experiences with suffering and death; but these experiences have also generated positive psychological growth. Objective. Develop a model of structural equations to determine if coping with stress is a predictor of post-traumatic growth in a Peruvian population. Method . The design was predictive cross-sectional. 310 people participated, 58 % men and 42 % women, aged 18 to 63 years (M=31.6). The COPE-28 Spanish version (Morán et al., 2010) and the Postraumatic Growth Inventory PTGI (Tedeschi & Calhoun, 1996), adapted by Ramos-Vera et al (2021). Results . In the first model, the coping strategies religion (β=.209, p<.01), self-distraction (β=.111, p<.01) and disconnection (β=-.147, p<.05) are significant predictors and explain 14.9 % of post-traumatic growth; likewise, in the second model, spiritual coping styles (β=.209, p<.01), social support (β=.172, p<.05) and cognitive (β=.164, p<.05) are im portant predictors that explain 14.7 % of post-traumatic growth. Conclusions . The best predictor of growth is religious coping followed by distraction and disconnection. Also, spiritual coping styles, social support, and cognitive support are important predictors.

RESUMEN Antecedentes . La población peruana durante la Covid-19 ha estado expuesta a eventos es tresantes y traumáticos, asociados a experiencias cercanas con el sufrimiento y la muerte; pero estas vivencias también han generado un crecimiento psicológico positivo. Objetivo. Desarrollar un modelo de ecuaciones estructurales para determinar si el afrontamiento al estrés es un predictor del crecimiento postraumático en una población peruana. Método . El diseño fue predictivo transversal. Participaron 310 personas, 58 % varones y 42 % mujeres, de 18 a 63 años (M=31.6). Se usó el COPE-28 versión española (Morán et al., 2010) y el Postraumatic Growth Inventory PTGI (Tedeschi y Calhoun, 1996), adaptado por Ramos Vera et al. (2021). Resultados . En el primer modelo, las estrategias de afrontamiento religión (β=.209, p<,01), autodistracción (β=.111, p<,01) y desconexión (β=-.147, p<,05) son predic tores significativos y explican el 14.9 % del crecimiento postraumático; asimismo, en el se gundo modelo, los estilos de afrontamiento espiritual (β=.209, p<,01), apoyo social (β=.172, p<,05) y cognitivo (β=.164, p<,05) son predictores importantes que explican el 14.7 % del crecimiento postraumático. Conclusiones . El mejor predictor del crecimiento es el afronta miento religión seguido de distracción y desconexión. También, los estilos de afrontamiento espiritual, apoyo social y cognitivo son predictores importantes.

https://doi.org/10.15381/rinvp.v26i1.24484

12.

Metabolic effect of low fluoride levels in the islets of NOD mice: integrative morphological, immunohistochemical, and proteomic analyses
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TREVIZOL, Juliana Sanches

; DIONIZIO, Aline

; DELGADO, Aislan Quintiliano

; VENTURA, Talita Mendes Oliveira

; RIBEIRO, Caroline Fernanda da Silva

; RIBEIRO, Laura

; BUZALAF, Nathalia Rabelo

; CESTARI, Tânia Mary

; MAGALHÃES, Ana Carolina

; SUZUKI, Maiko

; BOSQUEIRO, José Roberto

; BUZALAF, Marília Afonso Rabelo

Journal of Applied Oral Science

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2023, Volume 31 elocation e20230036

Abstract: En | Text: En | PDF: En

Abstract Fluoride (F) has been widely used to control dental caries, and studies suggest beneficial effects against diabetes when a low dose of F is added to the drinking water (10 mgF/L). Objectives This study evaluated metabolic changes in pancreatic islets of NOD mice exposed to low doses of F and the main pathways altered by the treatment. Methodology In total, 42 female NOD mice were randomly divided into two groups, considering the concentration of F administered in the drinking water for 14 weeks: 0 or 10 mgF/L. After the experimental period, the pancreas was collected for morphological and immunohistochemical analysis, and the islets for proteomic analysis. Results In the morphological and immunohistochemical analysis, no significant differences were found in the percentage of cells labelled for insulin, glucagon, and acetylated histone H3, although the treated group had higher percentages than the control group. Moreover, no significant differences were found for the mean percentages of pancreatic areas occupied by islets and for the pancreatic inflammatory infiltrate between the control and treated groups. Proteomic analysis showed large increases in histones H3 and, to a lesser extent, in histone acetyltransferases, concomitant with a decrease in enzymes involved in the formation of acetyl-CoA, besides many changes in proteins involved in several metabolic pathways, especially energy metabolism. The conjunction analysis of these data showed an attempt by the organism to maintain protein synthesis in the islets, even with the dramatic changes in energy metabolism. Conclusion Our data suggests epigenetic alterations in the islets of NOD mice exposed to F levels comparable to those found in public supply water consumed by humans.

https://doi.org/10.1590/1678-7757-2023-0036

13.

Fístula arteriovenosa ilíaca à direita por rotura de aneurisma e aneurisma de artéria ilíaca esquerda: tratamento híbrido
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Araujo, Adalberto Pereira de

; Gomes, Cristiane Ferreira de Araujo

; Poschinger-Figueiredo, Douglas

; Delgado, Carlos Felipe da Silva

; Mayall, Monica Rochedo

; Campanario, Flavia Figueira Baltharejo

; Fagundes, Felipe Borges

Jornal Vascular Brasileiro

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2023, Volume 22 elocation e20220017

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

Abstract An arteriovenous fistula (AVF) is an uncommon sequela of spontaneous arterial aneurysm rupture into the adjacent venous system. We describe the case of a 74-year-old patient who underwent endovascular treatment of a right iliac AVF caused by a ruptured common iliac artery (CIA) aneurysm and a distal left CIA aneurysm. Surgery preserved the lumbar and inferior mesenteric arteries because of the need to simultaneously exclude the hypogastric arteries. Dynamic fluid balance phenomena provoked by closure of the AVF are described. The patient had a benign postoperative course with normalization of the severe hemodynamic changes presented prior to the intervention and resolution of respiratory symptoms attributed to pulmonary arterial hypertension.

Resumo A fístula arteriovenosa (FAV) é uma sequela incomum de rotura espontânea de aneurisma arterial dentro do sistema venoso adjacente. Descrevemos, em um paciente de 74 anos, o tratamento endovascular de FAV ilíaca à direita por aneurisma de artéria ilíaca comum (AIC) roto associado a aneurisma de AIC distal à esquerda, em cuja cirurgia foram preservadas as artérias lombares e mesentérica inferior por necessidade de excluir simultaneamente as artérias hipogástricas. Foram demonstrados os fenômenos na dinâmica do balanço hídrico ocorridos em decorrência da interrupção da FAV. A evolução do paciente foi benigna, com normalização das graves alterações hemodinâmicas que apresentava e com desaparecimento dos sintomas respiratórios atribuídos à hipertensão arterial pulmonar.

https://doi.org/10.1590/1677-5449.202200171

14.

Economic valuation of the ecosystem of the high Andean hydrographic basin tributary of the Chumbao River, through multicriteria analysis
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Barrial-Lujan, A. I.

; Rodríguez, G.

; Huamán-Carrión, M. L.

; Espinoza-Montes, F.

; Barrial-Acosta, D.

; Delgado Laime, M. C.

; Arevalo-Quijano, J. C.

; Castro-Paniagua, W. G.

; Barrial-Lujan, C.

; Reynoso-Canicani, D. D.

Brazilian Journal of Biology

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2023, Volume 83 elocation e277697

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

Abstract Environmental wealth is the main basis of the social, cultural and economic development of a country, but if there is an absence of the valuation of these natural resources, it can lead to a disproportionate usufruct that causes the deterioration of the ecosystem and even collateral effects of human health. This research aimed to know the total economic value of the ecosystem of the high Andean water basin tributary of the Chumbao River, located between 2000 to 4800 meters above sea level belonging to the province of Andahuaylas, Apurimac region in Perú. The valuation procedure consisted of using the analytical method of multicriteria valuation applying the concept of Total Economic Value, which involved direct and indirect uses related to environmental assets, in which a collective panel of people from different training disciplines (experts) participated, which were made up of researchers, engineers, public officials, farmers and ecologists who had extensive knowledge about the environmental asset. of the geographical area in reference; and once the paired comparison survey was done, the total economic value was quantified up to three amounts, so the respondents were formed into three statistically significant segments (SIG<0.05). The cluster (1): assigned a weighting that quantifies to an economic value of USS 4,359,179,489.46; followed by cluster (2): an intermediate value of USS 4,029,902,444.41 and cluster (3): assigned a lower value to USS 774,163,167.16. Thus, it follows that, on average, 51.78% equals value in use and 48.21% equals value in non-use, respectively. This value expressed as an interval reflects the environmental ethical positions of the groups and makes available as an indicator to government authorities and society in order to exercise actions of environmental sustainability high andean.

Resumo A riqueza ambiental é a principal base do desenvolvimento social, cultural e econômico de um país, todavia, se não houver a valorização desses recursos naturais, pode levar a um usufruto desproporcional que causa a deterioração do ecossistema e até mesmo efeitos colaterais da saúde humana. Esta pesquisa teve como objetivo conhecer o valor econômico total do ecossistema da alta bacia hidrográfica andina afluente do rio Chumbao, localizado entre 2.000 e 4.800 metros acima do nível do mar pertencente à província de Andahuaylas, região de Apurimac no Peru. O procedimento de avaliação consistiu na utilização do método analítico de avaliação multicritério aplicando o conceito de Valor Econômico Total, que envolveu usos diretos e indiretos relacionados a ativos ambientais, no qual participou um painel coletivo de pessoas de diferentes disciplinas de formação (especialistas), composta por pesquisadores, engenheiros, funcionários públicos, agricultores e ecologistas que possuíam amplo conhecimento sobre o bem ambiental. da área geográfica em referência; e uma vez feito o levantamento de comparação pareada, o valor econômico total foi quantificado em até três valores, de forma que os respondentes foram divididos em três segmentos estatisticamente significativos (SIG < 0,05). O cluster (1): atribuído um peso que quantifica a um valor econômico de US$ 4.359.179.489,46; seguido pelo cluster (2): um valor intermediário de US$ 4.029.902.444,41 e cluster (3): atribuiu um valor inferior a US$ 774.163.167,16. Assim, conclui-se que, em média, 51,78% equivalem a valor em uso e 48,21% equivalem a valor em não uso, respectivamente. Este valor expresso como um intervalo reflete as posições éticas ambientais dos grupos e disponibiliza como um indicador para as autoridades governamentais e a sociedade a fim de exercer ações de sustentabilidade ambiental alto andino.

https://doi.org/10.1590/1519-6984.277697

15.

Cross-cultural invariance of the Spanish version of the COVID-19 Assessment Scorecard to measure the perception of government actions against COVID-19 in Latin America
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Caycho-Rodríguez, Tomás

; Valencia, Pablo D.

; Ventura-León, José

; Carbajal-León, Carlos

; Vilca, Lindsey W.

; Reyes-Bossio, Mario

; Delgado-Campusano, Mariel

; Yupanqui-Lorenzo, Daniel E.

; Paredes-Angeles, Rubí

; Rojas-Jara, Claudio

; Gallegos, Miguel

; Cervigni, Mauricio

; Martino, Pablo

; Polanco-Carrasco, Roberto

; Palacios, Diego Alejandro

; Moreta-Herrera, Rodrigo

; Samaniego-Pinho, Antonio

; Rivera, Marlon Elías Lobos

; Figares, Andrés Buschiazzo

; Puerta-Cortés, Diana Ximena

; Corrales-Reyes, Ibraín Enrique

; Calderón, Raymundo

; Gallegos, Walter L. Arias

; Petzold, Olimpia

; Camargo, Andrés

; Torales, Julio

; Blanco, J. Arkangel Monge

; González, Pedronel

; Smith-Castro, Vanessa

; Rivera, Wendy Yamilet Matute

; Ferrufino-Borja, Daniela

; Ceballos-Vásquez, Paula

; Muñoz-del-Carpio-Toia, Agueda

; Palacios, Jorge

; Burgos-Videla, Carmen

; León, Ana María Eduviges Florez

; Vergara, Ibeth

; Vega, Diego

; Barria-Asenjo, Nicol A.

; Schulmeyer, Marion K.

; Rios, Hassell Tatiana Urrutia

; Lira, Arelly Esther Lira

Psicologia: Reflexão e Crítica

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2023, Volume 36 elocation 34

Abstract: En | Text: En | PDF: En

Abstract Objectives The present study aimed to evaluate the measurement invariance of a general measure of the perception of governmental responses to COVID-|19 (COVID-SCORE-10) in the general population of 13 Latin American countries. Methods A total of 5780 individuals from 13 Latin American and Caribbean countries selected by non-probabilistic snowball sampling participated. A confirmatory factor analysis was performed and the alignment method was used to evaluate invariance. Additionally, a graded response model was used for the assessment of item characteristics. Results The results indicate that there is approximate measurement invariance of the COVID-SCORE-10 among the participating countries. Furthermore, IRT results suggest that the COVID-SCORE-10 measures with good psychometric ability a broad spectrum of the construct assessed, especially around average levels. Comparison of COVID-SCORE-10 scores indicated that participants from Cuba, Uruguay and El Salvador had the most positive perceptions of government actions to address the pandemic. Thus, the underlying construct of perception of government actions was equivalent in all countries. Conclusion The results show the importance of initially establishing the fundamental measurement properties and MI before inferring the cross-cultural universality of the construct to be measured.

https://doi.org/10.1186/s41155-023-00277-9

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