Abstract MS is extensively used in oil and gas industries, but its inherent susceptibility to corrosive attack in marine environments with high C of Cl- is a shortcoming to its applications in such inevitable medium. Coating has been a popular means of mitigating steel structures corrosion. This work assessed the effect of Zn-ZnO based AW-SS composite as AC material on a MS substrate in a marine environment. The Zn-ZnO base was separately subject to CD with SS, DLFA and LSLA particulates on MS substrates. PDP method was used to ascertain corrosion behaviors of the coated samples in a simulated SW environment. The samples ( and microstructural properties were studied by a microhardness tester and SEM, respectively. The results indicated that the samples ( increased when they were coated by SS and LSLA higher C, which had the highest and lowest (, respectively. The coatings CP improved visibly with SS, which had the highest value (61.4%), followed by DLFA (53.8%) and LSLA (44.3%). AW incorporated into Zn-ZnO is a potential AC material.

ABSTRACT Neea is one of the largest genera of Nyctaginaceae and comprises approximately 80 species distributed in the Neotropical region. Here, we report for the first time the occurrence of Neea madeirana in Peru, almost 50 years after it was first collected in this country, but was misidentified as Guapira noxia. We also insert N. madeirana in the identification key for Peruvian species of Neea and update the distribution map of N. madeirana. Given that we have not located any posterior specimen of G. noxia in Peruvian collections, and the original specimens cited as G. noxia correspond to N. madeirana, we suggest the exclusion of G. noxia from the Peruvian flora checklist.

RESUMO Neea é um dos maiores gêneros de Nyctaginaceae e compreende aproximadamente 80 espécies distribuídas na região neotropical. Aqui, relatamos, pela primeira vez, a ocorrência de Neea madeirana no Peru, quase 50 anos depois de ter sido coletada pela primeira vez neste país, mas foi erroneamente identificada como Guapira noxia. Também inserimos N. madeirana na chave de identificação para espécies peruanas de Neea e atualizamos o mapa de distribuição de N. madeirana. Dado que não localizamos nenhum espécime posterior de G. noxia nas coleções peruanas, e os espécimes originais citados como G. noxia correspondem a N. madeirana, sugerimos a exclusão de G. noxia da flora peruana.

Resumen Antecedentes y objetivos: algunos estudios han demostrado una relación entre los niveles de 25-hidroxivitamina D y la presencia del síndrome metabólico. El objetivo de este estudio fue evaluar si existe una asociación entre la 25-hidroxivitamina D, la variante rs2282679 del gen GC y el síndrome metabólico (SM). Métodos: el estudio involucró a una población de 134 mujeres obesas posmenopáusicas. Se registraron parámetros antropométricos, presión arterial, marcadores de recambio óseo, glucemia en ayunas, resistencia a la insulina (HOMA-IR), perfil lipídico, proteína C reactiva y prevalencia de SM. Se evaluó el genotipo del polimorfismo del gen CG (rs2282679). Resultados: los niveles de insulina (delta: 4,6 ± 0,9 mUI/l; p = 0.02), triglicéridos (delta: 21,6 ± 2,9 mg/dl; p = 0,04) y HOMA-IR (delta: 1,1 ± 0,9 unidades; p = 0,02) fueron menores en los sujetos TT que en los pacientes TG + GG. Los porcentajes de individuos que tenían SM (OR = 2,80, IC 95 % = 1,39-5,65; p = 0,02), hipertrigliceridemia (OR = 2,39, IC 95 % = 1,44-5,96; p = 0,01) e hiperglucemia (OR = 2,72, IC 95 % = 1,23-6,00; p = 0,43) fueron mayores en los portadores del alelo G. El análisis de regresión logística mostró un mayor riesgo de SM en los portadores del alelo G (OR = 2,36, IC 95 % = 1,11-5,91; p = 0,02) y un mayor riesgo de deficiencia de 25-hidroxivitamina D (< 20 ng/ml) (OR = 2,43, IC 95 % = 1,13-6,69; p = 0,02). Conclusiones: en esta población hemos detectado una asociación negativa entre el alelo G y la resistencia a la insulina, hipertrigliceridemia, deficiencia niveles de 25-hidroxivitamina D y SM.

Abstract Background and aims: some studies have reported links between 25-hydroxyvitamin D levels and the presence of metabolic syndrome. The aim of the present study was to evaluate whether an association exists among 25-hydroxyvitamin D, rs2282679 of the GC gene and metabolic syndrome (MS). Methods: the study involved a population of 134 postmenopausal obese females. Measurements of anthropometric parameters, blood pressure, bone turnover markers, fasting blood glucose, insulin resistance (HOMA-IR), lipid profile, C-reactive protein and prevalence of MS were recorded. Genotype of CG gene polymorphism (rs2282679) was evaluated. Results: insulin (delta: 4.6 ± 0.9 mUI/l; p = 0.02), triglycerides (delta: 21.6 ± 2.9 mg/dl; p = 0.04) and HOMA-IR (delta: 1.1 ± 0.9 unit; p = 0.02) were lower in TT subjects than TG + GG patients. The percentages of individuals who had MS (OR = 2.80, 95 % CI = 1.39-5.65; p = 0.02), hypertriglyceridemia (OR = 2.39, 95 % CI = 1.44-5.96; p = 0.01), and hyperglycemia (OR = 2.72, 95 % CI = 1.23-6.00; p = 0.43) were higher in G allele carriers. Logistic regression analysis showed an increased risk of MS in G allele carriers (OR = 2.36, 95 % CI = 1.11-5.91, p = 0.02) and an increased risk of 25-hydroxyvitamin D deficiency (< 20 ng/ml) (OR = 2.43, 95 % CI = 1.13-6.69, p = 0.02), too. Conclusions: a negative association among G allele and insulin resistance, hypertriglyceridemia, deficiency of 25 hydroxyvitamin D levels and MS was reported in this population.

ABSTRACT Operational speed influences the soil preparation quality, the first established according to the working set performance and its traction capacity. The experiment's objective is to determine the influence of working speed on energy and operational performance of an agricultural tractor with Full-Powershift transmission when performing a harrowing operation. We conducted the experiment using lines, in a randomized block design. It had four operational soil preparation speeds, with seven repetitions, totaling 28 experimental units. We measured the following parameters per worked area: slipping, engine rotation, specific and per hour fuel consumption, strength, power, and yield on the drawbar and operating speed. Additionally, we analyzed soil profilometry parameters concerning the mobilized area and working thickness. We also evaluated the variance of the collected data and, when significant, submitted it to a regression test. The data showed that higher operating speeds result in greater operational performance and reduction of the energy demand of the mechanized set under study. In addition, this increase doesn't have a beneficial effect on grid fluctuation, not affecting the quality of soil preparation.

ABSTRACT Automatic production management (APM) is a tool that assists in the operations of agricultural tractors, increasing yield and energy efficiency. The objective of the experiment was to compare the energy and operational performance of a 373-kW articulated tractor equipped with APM and manual mode of engine transmission and rotation, across different real-world speeds. The experiment was conducted in a randomized block design with five replicates, using a split-plot arrangement with two system modes (manual and automatic) in the plots and four real-world speeds (4, 6, 8, and 10 km h-1) in the subplots, totaling 40 experimental units. The evaluated variables were: wheel slippage; engine rotation; hourly and specific fuel consumptions; drawbar force, power, and yield; operating speed; and engine thermal efficiency. The variance of the data was analyzed using Tukey’s test for the first factor, and regression analysis for the second factor and interactions. The automatic mode showed lower engine rotation and wheel slippage without compromising the other variables. The use of this mode showed energy advantages at 4 and 6 km h-1 by resulting in less fuel consumption per hour. In addition, the manual mode presented higher thermal efficiency at lower speeds than the automatic mode, which showed a linear increase.

RESUMO O gerenciamento automático de produtividade (APM) presente no trator agrícola é uma ferramenta importante que auxilia na operação, aumentando a eficiência e rendimento energético. O objetivo do experimento foi comparar o desempenho operacional e energético de um trator articulado de 373 kW equipado com APM e com o modo manual da transmissão e rotação do motor, sob diferentes velocidades reais. O experimento foi conduzido no delineamento de blocos casualizados em esquema de parcelas subdivididas, sendo as parcelas constituídas de dois modos de transmissão (manual e automático) e as subparcelas de quatro velocidades reais (4, 6, 8 e 10 km h-1), com cinco repetições, totalizando 40 unidades experimentais. Foram monitorados a patinagem dos rodados, rotação do motor, consumo horário e específico de combustível, força, potência e rendimento na barra de tração, velocidade operacional e eficiência térmica do motor. Os dados coletados foram submetidos à análise de variância, sendo o primeiro fator analisado pelo teste de Tukey, e o segundo fator e as interações por análise de regressão. No modo automático a rotação do motor e a patinagem dos rodados foram menores sem comprometer as demais variáveis. Além disso, este modo, a 4 e 6 km h-1, demonstrou uma vantagem energética, que requer menor consumo de combustível por hora. Além disso, o modo manual apresentou maior eficiência térmica em velocidades mais baixas quando comparado com o modo automático, que apresentou um aumento linear.

Toads of the Rhinella genus have a pair of paratoid glands that store biological secretions of high toxicity and varied chemical composition, rich in biologically active compounds. The present work aimed to carry out the investigation of the metabolomic profile and evaluation of the biological potential of the secretion paratoid glands (PGS) from Rhinella granulosa. The paratoid secretion was collected in the Piauí state (Brazil), extracted with methanol and the extract was analyzed by ultra-performance liquid chromatography with quadrupole time-of-flight mass spectrometry. Fifty chemical constituents were identified. The extract showed cytotoxicity against tumor cell lines of the central nervous system (half maximal inhibitory concentration (IC50) = 1.9 µg mL-1) and prostate (IC50 = 1.6 µg mL-1), unsatisfactory antimicrobial potential (minimal inhibitory concentration (MIC) > 312 µg mL-1) and inhibited the enzyme acetylcholinesterase (IC50 = 5.119 mg mL-1). The results presented relevant information about the PGS and contributed to the understanding of the metabolomic and biological potential of R. granulosa.

Resumen Objetivo: La enfermedad vascular periférica (EVP) afecta generalmente múltiples segmentos de los miembros. Existe información contradictoria con respecto al pronóstico de pacientes con enfermedad aortoilíaca, sin embargo, la diabetes y la enfermedad critica de miembros inferiores habitualmente afecta el territorio infrapatelar. Nuestro objetivo es determinar el impacto de la afectación infrapatelar en eventos cardiovasculares. Métodos: Estudio retrospectivo, observacional en un hospital universitario de Argentina. Se revisó la historia clínica electrónica de pacientes con EVP con requerimiento de revascularización. Se generó un modelo de regresión multivariado incluyendo variables clínicamente relevantes. El punto final primario fue un combinado de hospitalización por isquemia crítica y amputaciones mayores entre pacientes con afectación infrapatelar y suprapatelar. Amputaciones menores, muerte por todas las causas, infarto agudo de miocardio (IAM), accidente cerebrovascular (ACV) y un combinado de eventos cardiovasculares (MACE) fueron los puntos secundarios. Resultados: Se reclutó un total de 309 pacientes desde enero de 2014 hasta julio de 2020. 151 pacientes presentaron enfermedad suprapatelar y 158 infrapatelar. El punto final primario ocurrió en 35 pacientes (22.2%) en el grupo infrapatelar y en 18 pacientes (11.9%) en suprapatelares (HR 2.16; intervalo de confianza 95% [1.22-3.82]; p = 0.008). Ambos componentes ocurrieron con mayor frecuencia en pacientes con afectación infrapatelar. Los eventos de amputación menor fueron mas prevalentes en pacientes con afectación infrapatelar (HR 5.09; IC95% [1.47-17.6]; p = 0.010) La mortalidad por todas las causas, IAM, ACV y MACE no fueron diferentes entre los grupos (p > 0.05). Conclusión: La enfermedad infrapatelar fue un factor independiente para mayor riesgo de hospitalización por isquemia critica, amputación mayor y menor comparado con pacientes con afectación suprapatelar en EVP sintomática revascularizada.

Abstract Background: Peripheral artery disease (PAD) frequently affects multiple segments of the limbs. Contradictory data have reported worse prognosis in aortoiliac lesions, nevertheless, diabetes and chronic limb ischemia frequently affects the infrapatellar territory. Our aim was to assess the impact of infrapatellar disease in cardiovascular outcomes. Methods: We performed a retrospective, observational cohort study at a university hospital in Argentina. Electronic health records were retrospectively reviewed including symptomatic PAD patients requiring revascularization. A multivariable regression model was performed to account for confounders. The primary endpoint was a composite of hospitalizations due to chronic limb threatening ischemia (CLTI) and major amputation events between infrapatellar and suprapatellar patients. Minor amputation events, all-cause death, myocardial infarction (MI), stroke, and major cardiovascular events (MACE) were secondary endpoints. Results: From January 2014 through July 2020, a total of 309 patients were included in the analysis. 151 patients had suprapatellar disease, and 158 had infrapatellar disease. The primary composite endpoint occurred in 35 patients (22.2%) in the infrapatellar patients and 18 patients (11.9%) in the suprapatellar patients (HR = 2.16; 95% confidence interval [CI] = [1.22-3.82]; p = 0.008). Both components of the primary outcomes occurred more frequently in infrapatellar patients. Minor amputation events were more prevalent in infrapatellar patients (HR = 5.09; 95% CI = [1.47-17.6]; p = 0.010). Death, MI, stroke, and MACE events were not different among groups (all p > 0.05). Conclusion: Infrapatellar disease was an independent factor for increased hospitalization of CLTI, major and minor amputations events, compared to suprapatellar disease in symptomatic revascularized PAD patients.

Abstract: This article analyzes the repercussions of G. Politzer’s thought on the philosophy of life elaborated by G. Canguilhem. During the first thirty years of the twentieth century, Politzer’s texts provide important material for the construction of the philosophy that Canguilhem builds on human individuality and its autonomy. The reading of Politzer constitutes for Canguilhem a motive of inspiration for his axiological, moral and political proposals. By associating the ideas of the concrete psychology that encapsulates the existence of man-actor, Canguilhem reconciles two series of arguments: a). the philosophy of life cannot do without an approach to human action; b). the presence of human action becomes inseparable from the assumptions that debate its existence between the singularity of its productions, and the apprehension that can be made of it by means of the universals that are proposed by science.

Resumen: El presente articulo analiza las repercusiones del pensamiento de G. Politzer en la filosofía de la vida elaborada por G. Canguilhem. Durante los primeros treinta años del siglo XX, los textos de Politzer brindan un material importante para la construcción de la filosofía que Canguilhem construye a propósito de la individualidad humana y su autonomía. La lectura de Politzer constituye para Canguilhem, un motivo de inspiración de sus propuestas axiológicas, morales y políticas. Asociando las ideas de la psicología concreta que encumbra la existencia del hombre-actor, Canguilhem concilia dos series de argumentos: a). la filosofía de la vida no puede prescindir de un planteamiento relativo a la acción humana; b). la presencia de la acción humana se torna indisociable de los supuestos que debaten su existencia entre la singularidad de sus producciones, y la aprehensión que de ella puede realizarse por medio de los universales que son propuestos por la ciencia.

RESUMO A qualidade desta operação de preparo do solo pode ser mensurada por equipamentos denominados perfilômetros, fornecendo informações quanto a rugosidade, área mobilizada, empolamento e espessura do solo trabalhada. Porém, trata-se de equipamento antiquado, com elevadas horas de trabalho no campo e escritório. Assim, o objetivo do trabalho foi construir um perfilômetro eletrônico utilizando triangulação a laser e sensores de ultrassom para medição de perfis de solo mobilizados digitalmente. Em seguida, os resultados obtidos foram comparados com os obtidos com um perfilômetro de barra deslizante tradicional para avaliar a precisão e eficiência dos sensores. Para o experimento conduzido em ambiente controlado, adotou-se o delineamento inteiramente casualizado. As variáveis foram mensuradas, sete vezes, através dos três perfilômetros (eletrônico a laser, eletrônico a ultrassom e o tradicional) nos perfis original, elevado e mobilizado do solo. Verificou-se que o perfilômetro eletrônico com ultrassom diferiu na totalidade das mensurações em relação ao perfilômetro convencional, com o sensor a laser apenas na rugosidade modificada. mobilizada trabalhada Porém tratase trata se antiquado escritório Assim digitalmente seguida controlado adotouse adotou casualizado mensuradas vezes original Verificouse Verificou convencional modificada

ABSTRACT The quality of soil tillage can be measured with a specific device called profilometer, which provides information on roughness, mobilized area, blistering, and thickness in disturbed soils. However, it is an outdated device, requiring many hours of field and office work. Thus, the objective of the present work was to develop an electronic profilometer using laser triangulation and ultrasound sensors for measurement of digitally mobilized soil profile. The results obtained were compared to those acquired with a conventional sliding bar profilometer to evaluate the accuracy and efficiency of the sensors. The experiment was conducted in a completely randomized design under a controlled environment. The variables were measured seven times using the three profilometers (laser, ultrasound, and conventional) in the original, elevated, and mobilized soil profiles. The electronic profilometer with ultrasound differed in all the measurements when compared to the conventional profilometer, which differed from the laser sensor only in modified roughness. roughness area blistering soils However Thus profile environment laser, (laser original elevated profiles

RESUMO Um dos processos mais usados para garantir a qualidade dos grãos em grandes armazéns é a aeração. Um modelo de otimização que considere a natureza limitada e discreta das entradas de ar, além das características geométricas do armazém dos grãos, pode produzir resultados mais facilmente aplicáveis no design de novos armazéns graneleiros. O objetivo deste estudo foi parametrizar e aplicar o modelo de Darcy-Forchheimer para simulação de fluxo de ar em massa de grãos de soja em função da altura da camada de grãos e desenvolver um método de inteligência artificial baseado em algoritmos genéticos para otimizar as dimensões do armazém de grãos e a configuração das entradas de ar para obter um fluxo de ar mais homogêneo na massa de grãos. A parametrização considerou o efeito da compactação dos grãos e as simulações em OpenFOAM mostraram boa concordância com os dados experimentais. O algoritmo genético proposto foi capaz de aumentar a homogeneidade do fluxo de ar se comparada ao armazém usado como referência. aeração graneleiros DarcyForchheimer Darcy Forchheimer experimentais referência

ABSTRACT One of the main processes used to maintain grain quality in large storage bins is aeration. An optimization model that considers the limited and discrete nature of the air inlets, in addition to the geometric characteristics of the storage bin, could produce results more easily applicable results for the design of new grain storage bins. The objective of this study was to parameterize and to apply the Darcy-Forchheimer model for simulating airflow in soybean grain mass as function of grain layer height, and develop an artificial intelligence method based on genetic algorithm for optimizing grain storage bin dimensions and air inlet configurations to obtain a more homogeneous airflow in the grain mass. The parameterization considered the effect of grain compaction and the OpenFOAM simulations showed good agreement with the experimental data. The proposed genetic algorithm was able to increase the airflow homogenization when compared to the grain storage bin used as reference. aeration inlets DarcyForchheimer Darcy Forchheimer height data reference

Resumen Introducción: La colocación de catéteres intravasculares venosos umbilicales (CVU) y arteriales (CAU) es el procedimiento invasivo más frecuente en la unidad de cuidados intensivos neonatales (UCIN). Para introducirlos se utilizan las fórmulas de Wright y de Shukla, aunque esta última podría estar asociada con una inserción incorrecta, especialmente en neonatos < 1500 g. El objetivo de este estudio fue determinar mediante radiografía de tórax cuál fórmula es mejor para la correcta colocación de catéteres umbilicales en recién nacidos ≤ 1500 g. Métodos: Se incluyeron los pacientes ingresados en la UCIN de un hospital de segundo nivel entre 2021-2022 que recibieron CVU o CAU mediante las fórmulas de Wrigth o Shukla. Resultados: Se incluyeron en total 129 recién nacidos: 78 CVU y 51 CAU. En CVU, Wright 50% y Shukla 36.8% tuvieron localización correcta, p = 0.24. En las CAU, Wright 56.6% y Shukla 52.4% tenían una ubicación correcta, p = 0.76. En CVU con peso < 1000 g, Wright 36.4% y Shukla 33.3% bien situados, p = 0.58. En CVU > 1000 g, Wright 66.6% y Shukla 38.4% bien situados, p = 0.065. En CAU < 1000 g, Wright 45% y Shukla 42.9%, p = 0.63. En CAU con peso > 1000 g, Wright 80% y Shukla 57.1%, p = 0.23. Conclusiones: La colocación del CVU fue 13% mejor con la fórmula de Wright. La fórmula de Wright superó en el 29% la colocación del CVU en los neonatos > 1000 g en comparación con la de Shukla, aunque no hubo diferencia significativa debido al tamaño de la muestra.

Abstract Background: Intravascular venous (VUC) or arterial (AUC) umbilical catheter placement is the most frequent invasive procedure in the neonatal intensive care unit (NICU). Either Wright’s or Shukla’s formula is used to introduce the catheters. However, Shukla’s formula is associated with incorrect insertion, especially for newborns < 1500 g. This study aimed to determine by chest X-ray if Wright’s formula is better than Shukla’s formula for the correct placement of umbilical catheters in newborns ≤ 1500 g. Methods: We included patients admitted to the NICU of a secondary-level hospital between 2021-2022 who received VUC or AUC through the Wright or Shukla formulas. Results: A total of 129 newborns were included: 78 with VUC and 51 with AUC. In VUC, 50% with Wright and 36.8% with Shukla formulas had the correct location, (p = 0.24). In AUC, 56.6 % with Wright and 52.4% with Shukla formulas were placed correctly placed, (p = 0.76). VUC with weight < 1000 g were correctly placed in 36.4% with Wright and 33.3% with Shukla formulas (p = 0.58). VUC in newborns > 1000 g were correctly placed in 66.6% with Wright and 38.4% with Shukla formulas (p = 0.065). AUC in newborns < 1000 g were correctly placed in 45% using Wright and 42.9% Shukla formulas (p = 0.63). AUC in newborns > 1000 g were correctly placed in 80% using Wright and 57.1% Shukla formulas (p = 0.23). Conclusions: We found 13% more correctly placed VUC using Wright’s formula. Moreover, Wright’s formula was 29% above Shukla’s VUC placement in neonates > 1000 g, although there was no significant difference due to the sample size.

Resumen Antecedentes: El lupus eritematoso sistémico (LES) es una enfermedad auto inmunitaria crónica multisistémica con diversas manifestaciones clínicas. Siendo las mujeres la pobla ción vulnerable y con mayor afectación a nivel neurológico, al presentar mayor riesgo de convulsiones. Las manifestaciones neuropsiquiátricas ocurren en etapas tempranas de la enfermedad y del diagnóstico, ya que pueden presentarse junto con manifestaciones sistémicas o no. La frecuencia de manifestaciones neuropsiquiátricas en el lupus eritematoso sistémico se ha descrito del 14 al 75%, siendo las alteraciones cognitivas uno de los grandes síntomas a destacar1. La cual puede ir acompañada de trastornos afectivos de tipo depresión y ansiedad. Ya que la psicosis secundaria a LES se remarca por su baja prevalencia (10%)2, los estudios de laboratorio nos suelen orientar hacia el diagnóstico definitivo, siendo los anticuerpos ribosomales P los que se han relacionado más específicamente con la psicosis lúpica. La resonancia magnética es la prueba de elección y las lesiones cerebrales están dominadas por hiperintensidades de materia blanca en forma de punción3. En el siguiente reporte de caso, presentamos a una paciente de 20 años, la cual contaba con antecedentes de esteatosis hepática diagnosticado, diabetes tipo MODY y resección de ovario derecho por teratoma maduro de 9 años de evolución, pero sin antecedentes psiquiátricos de importancia para el momento de su valoración. Sin embargo, de forma aguda presentó un brote psicótico caracterizado por ideas delirantes de grandiosidad y referencia, así como alteraciones conductuales, cognitivas y afectivas. Por las que tuvieron que acudir a hospital de 3er nivel durante el periodo de contingencia sanitaria en el 2020. Tras el antecedente de presentar infección por SARS-CoV-2 tres meses antes de su patología neuropsiquiátricas. Se sospechó en síntomas neurológicos secundarios a infección por COVID-19, así como patología psiquiátrica aislada. Por lo que se realizó abordaje de estudio de primer brote psicótico, diagnosticándose lupus eritematoso sistémico con manifestaciones neuropsiquiátricas. El tratamiento se basó en un bolo de metilprednisolona y antipsicóticos, luego modificada por terapia con corticoesteroides orales y antipsicótico de depósito. Conclusión: El lupus eritematoso sistémico con manifestaciones neuropsiquiátricas es una presentación poco frecuente del padecimiento, por la amplia variación en la aparición de este, los pacientes con síntomas psiquiátricos en contexto de hospital general deben de ser tomados en cuenta para abordajes extensos4. De la misma forma, el tener este conocimiento del caso podrá ampliar nuestro conocimiento sobre las complicaciones de esta patología reumatológica. Y una de sus complicaciones más graves como la psicosis lúpica para poder realizar un mejor abordaje del primer brote psicótico en hospitales generales, donde la valoración de un especialista puede ser más complicada para mejorar las condiciones médicas de estos pacientes.

Abstract Background: Systemic lupus erythematosus is a chronic multisystemic autoimmune disease with diverse clinical manifestations. Women are the most vulnerable population and have the greatest neurological involvement with a higher risk of seizures. Neuropsychiatric manifestations occur in early stages of the disease and diagnosis since they can occur together with systemic manifestations or not. The frequency of neuropsychiatric manifestations in systemic lupus erythematosus has been described from 14 to 75%; being cognitive alterations one of the major symptoms to highlight. Which, in the same way can be accompanied by affective disorders such as depression and anxiety. Since psychosis, secondary to SLE, stands out for its low prevalence (10%), laboratory studies usually guide us towards a definitive diagnosis, being ribosomal P antibodies the ones that have been more specifically related to lupus psychosis. MRI is the test of choice and brain lesions are dominated by punctate white matter hyperintensities. In the following case report, we present a 20-year-old patient who had a history of diagnosed hepatic steatosis, MODY type diabetes and resection of the right ovary for mature teratoma of 9 years of evolution; but with no psychiatric history of importance at the time of her evaluation. However, she acutely presented a psychotic outbreak characterized by delusions of grandiosity and reference; as well as behavioral, cognitive, and affective alterations. For which she had to go to a 3rd level hospital during the period of health contingency in 2020. After a history of SARS-CoV-2 infection three months before her neuropsychiatric pathology, neurological symptoms secondary to COVID-19 infection were suspected, as well as isolated psychiatric pathology. Therefore, a study approach of the first psychotic outbreak was performed, diagnosing systemic lupus erythematosus with neuropsychiatric manifestations. Treatment was based on a bolus of methylprednisolone and antipsychotics; later modified by therapy with oral corticosteroids and depot antipsychotic. Conclusion: Systemic lupus erythematosus with neuropsychiatric manifestations is an infrequent presentation of the disease, because of the wide variation in its appearance, patients with psychiatric symptoms in a general hospital setting should be considered for extensive approaches. In the same way, having this knowledge of this case may broaden our knowledge about the complications of this rheumatologic pathology. And one of its most serious complications such as lupus psychosis to be able to make a better approach to the first psychotic outbreak in general hospitals, where the assessment of a specialist can be more complicated.

Resumen Se evaluó la calidad nutritiva del rastrojo de dos cultivares criollos de maíz y un híbrido, colonizados por micelio de Ganoderma lucidum. El diseño experimental fue completamente al azar con arreglo factorial 3x4 con un tratamiento adicional y cuatro repeticiones. Cada cultivar tuvo rastrojo colonizado por el hongo hasta los 15 días, rastrojo en su estado natural (sin tratar), a tiempo cero después de la esterilización, a 15 días después de la esterilización y el micelio puro (adicional). Se determinó digestibilidad in vitro (DIVMS), fibra detergente neutro (FDN) y ácido (FDA), lignina y proteína cruda (PC). Los cultivares difirieron (P<0.0001) en digestibilidad, el criollo A presentó valores mayores. Los rastrojos colonizados tuvieron menor (P<0.05) digestibilidad; los rastrojos sin tratar tuvieron valores medios y los esterilizados fueron los más digestibles. La concentración de FDN, FDA, lignina, y PC difirió (P<0.0001) en los cultivares y las condiciones del rastrojo (P<0.0001). El criollo A tuvo menos FDN que los otros cultivares. Los rastrojos en su forma natural tuvieron menos FDN que los esterilizados y los colonizados. En la FDA los rastrojos en su forma natural tuvieron concentración baja, los esterilizados una concentración media y los colonizados la concentración mayor, situación que fue similar para lignina. En PC los cultivares fueron diferentes (P<0.0001), siendo los rastrojos colonizados los que tuvieron valores mayores (P<0.05). En conclusión, la colonización del rastrojo por el micelio de Ganoderma lucidum no aumentó la digestibilidad a los 15 días de colonización, lo que mejoró ligeramente fue la concentración de proteína cruda.

Abstract Nutritional quality in grain by-products such as corn stover can be improved with processes such as steam sterilization and fungus inoculation. The stover of two native corn cultivars and one commercial hybrid cultivar were steam sterilized or inoculated with mycelium of the white-rot fungus Ganoderma lucidum. The experimental design was completely random with a 3x4 factorial arrangement, one additional treatment and four replicates. The four treatments were untreated stover, sterilization and immediate drying, sterilization and drying after 15 d, and colonization with G. lucidum for 15 d; pure mycelia were also analyzed to establish values for the fungus. Five variables were measured: in vitro dry matter digestibility (IVDMD), neutral detergent fiber (NDF), acid detergent fiber (ADF), lignin and crude protein (CP). The three cultivars differed (P<0.0001) in terms of digestibility, with cultivar A having the highest values. Digestibility was lowest (P<0.05) in the G. lucidem-colonized stovers (P<0.05), intermediate in the untreated stovers and highest in the sterilized stovers. Contents of NDF, ADF, lignin, and CP differed (P<0.0001) between the cultivars and treatments (P<0.0001). Cultivar A had less NDF than the other cultivars. The untreated stovers had less NDF than the sterilized and G. lucidem-colonized stovers. For both ADF and lignin, the untreated stovers had the lowest values, the sterilized stovers had intermediate values and the colonized stovers had the highest. Crude protein (CP) differed between the cultivars (P<0.0001), and the colonized stovers had the highest values (P<0.05). Inoculation of corn stover with Ganoderma lucidum mycelia did not improve digestibility after fifteen days colonization, but slightly increased crude protein content.

ABSTRACT The evaluation of the physical attributes of the soil in cultivated areas is essential for understanding the impacts of agricultural operations, especially those with intense machine traffic. Therefore, the present study aimed to evaluate the physical attributes of the soil submitted to silage with different mechanized sets. A randomized block design was adopted with three treatments: forage harvester with a one-row cutting platform (T1), forage harvester with a three-row cutting platform (T2), and T2 with a forage harvester with a conveyor wagon. Before ensiling and 24 hours after the operation, intact samples of soil classified as Latossolo Vermelhoamarelo álico, intact, were collected to determine the micro, macro, and total porosity, soil density, and volumetric soil water content according to the methodology proposed by the Brazilian Agricultural Research Corporation (Embrapa). After ensiling, the resistance to soil penetration was measured with an electronic manual penetrometer, before and after ensiling, at the A horizon of the soil in the layers of 0.0-0.2 m and 0.2-0.4 m. We analyzed the data by establishing the confidence interval using the t-test at 10% probability. The sets reduce the macroporosity and total porosity of the soil in the 0.0-0.2 m and 0.2-0.4 m soil layers. T2 promoted greater total density in the 0.0–0.2 m layer. The silage increased the resistance to soil penetration to a depth of 0.15 m.

RESUMO A avaliação dos atributos físicos do solo em áreas cultivadas é essencial para a compreensão dos impactos das operações agrícolas, especialmente aquelas com intenso tráfego de máquinas. Sendo assim, o objetivo do trabalho foi avaliar atributos físicos do solo submetido a ensilagem com diferentes conjuntos mecanizados. Adotou-se um arranjo experimental de blocos casualizado com três tratamentos: ensiladora com plataforma de corte de uma linha (T1), ensiladora com plataforma de corte de três linhas (T2) e conjunto ensiladora T2 com carreta de transportadora. Antes da ensilagem e 24 horas após a operação, coletou-se amostras de solo classificado como Latossolo Vermelho-amarelo álico, intactas para determinar a micro, macro e porosidade total, densidade do solo e umidade volumétrica conforme metodologia proposta pela Empresa Brasileira de Pesquisa Agropecuária (Embrapa). Após a ensilagem mediu-se a resistência à penetração do solo com um penetrômetro manual eletrônico, antes e após a ensilagem, no horizonte A do solo nas camadas de 0,0 a 0,2 m e 0,2 a 0,4 m. Analisou-se os dados estabelecendo o intervalo de confiança conforme o teste t, a 10% de probabilidade. Os conjuntos reduzem a macroporosidade e porosidade total do solo, nas camadas de 0,0 a 0,2 m e 0,2 a 0,4 m. T2 propiciou maior densidade total na camada de 0,0 a 0,2 m. A ensilagem aumentou a resistência à penetração do solo até a profundidade de 0,15 m do mesmo.

ABSTRACT The management adopted for the mango crop requires that, at a certain stage, the irrigation depth should be reduced to promote a more uniform flowering. In regard to that, it is necessary to introduce new alternatives that mitigate the harmful effects of abiotic stress and that promote greater fruit yield. Therefore, the present study aimed to evaluate the influence of triacontanol on the levels of organic solutes, antioxidant enzymatic activity, and production of ‘Kent’ mango under Brazilian semi-arid conditions. The experiment was carried out for two consecutive years, 2018 and 2019, in a commercial orchard located at the DAN Farm, Petrolina-PE. The experimental design used was randomized blocks, with five treatments and four replications, evaluating four plants per plot. The treatments consisted of triacontanol doses: 0 (control treatment), 3.75; 7.50; 11.25, and 15.00 ppb per plant. Two consecutive harvests (2018 and 2019) were evaluated during the stages of branch maturation (2019 only), floral induction, full flowering, and initial fruiting. Foliar application of triacontanol positively favored the contents of total amino acids, free proline, total proteins, and activity of the enzymes superoxide dismutase (SOD), ascorbate peroxidase (APX), and catalase (CAT). There was an increase in production of 50.85% (dose - 11.25 ppb) and 64.95% (dose - 10.50 ppb) in the 2018 and 2019 crop years, respectively.

RESUMO O manejo adotado para a cultura da manga exige que, em determinada fase, a lâmina de irrigação seja reduzida para promover uma floração mais uniforme. Nesse sentido, é necessário inserir novas alternativas que atenuem os efeitos deletérios do estresse abiótico e que promovam maior produtividade de frutos. Portanto, o presente estudo teve como objetivo avaliar a influência do triacontanol sobre os teores de solutos orgânicos, atividade enzimática antioxidante e produção de mangueira ‘Kent’ nas condições do semiárido brasileiro. O experimento foi realizado em duas safras consecutivas, 2018 e 2019, em um pomar comercial localizado na Fazenda Dan, Petrolina-PE. O delineamento experimental utilizado foi em blocos casualizados, com cinco tratamentos e quatro repetições, sendo avaliadas quatro plantas por parcela. Os tratamentos consistiram em doses de triacontanol: 0 (tratamento controle); 3,75; 7,50; 11,25 e 15,00 ppb por planta. Duas safras consecutivas (2018 e 2019) foram avaliadas durante os estágios de maturação do ramo (somente 2019), indução floral, floração plena e frutificação inicial. Apesar das variações entre safras, observou-se que a aplicação foliar de triacontanol favoreceu positivamente os teores de aminoácidos totais, prolina livre, proteínas totais e atividade das enzimas superóxido dismutase (SOD), ascorbato peroxidase (APX) e catalase (CAT). Houve aumento na produção de 50,85% (na dose 11,25 ppb) e 64,95% (na dose 10,50 ppb) nas safras de 2018 e 2019, respectivamente.