Abstract Objective: To describe systemic manifestations, the characteristics related to tooth eruption, and the occurrence of enamel defects in children with Congenital Zika Virus Syndrome (CZS). Material and Methods: Prospective case series based on nine children with confirmed CZS diagnosis assisted at a reference center in a municipality in the Northeast Region of Brazil. Through a structured interview directed to mothers, information related to prenatal, delivery, and postpartum periods was collected. Tooth eruption was monitored through clinical examinations for 36 months. The modified developmental defect of enamel index (DDE) was used to identify opacities and hypoplasia. Data were presented using descriptive statistics. Results: A high proportion (77.8%) had microcephaly, and 55.5% had low birth weight. Musculoskeletal disorders, swallowing difficulty, and self-injury practices were present in all children. Among the systemic findings, visual impairment (77.8%) and seizures (77.8%) were widely reported. Concerning disorders related to the stomatognathic system, bruxism (66.7%) and difficulty in sucking (33.3%) were present. For most children (77.8%), the deciduous right lower central incisor was the first tooth to erupt (minimum 8 months and maximum 17 months). Enamel defects were diagnosed in only two children (22.2%). Conclusion: A wide range of systemic manifestations was observed in children with CZS, including visual impairment and musculoskeletal disorders. Delayed eruption of the first deciduous tooth was also observed. Enamel defects were present in a small proportion of children.

Resumo Os objetivos desta investigação foram descrever o perfil de homens e mulheres vítimas de violência e identificar fatores associados à gravidade do trauma facial. Foi realizado um estudo retrospectivo de 762 prontuários de vítimas atendidas no Instituto de Medicina Legal e Odontologia de uma região metropolitana do Nordeste do Brasil. A variável dependente foi o tipo de trauma facial sofrido pelas vítimas. Variáveis independentes foram as características sociodemográficas das vítimas, características dos agressores e circunstâncias de violência. Estatísticas descritivas, bivariadas (teste c2) e multivariadas foram feitas por meio de regressão logística. O nível de significância foi fixado em p<0,05. A idade média das vítimas foi de 29,78 anos (DP =13,33). Com base no modelo de regressão final, os indivíduos do sexo masculino [odds ratio (OR)=2,22, IC 95%=1,08-4,57, p=0,030], agredidos por outros sujeitos do sexo masculino (OR=4,88; IC 95%=1,12-21,26; p=0,035) por meio de instrumentos (OR=6,67; IC 95%=2,85-15,60; p<0,001) ou agressões mistas (OR=4,34; IC 95%=1,44-13,02; p=0,009) foram mais propensos a apresentar fraturas de ossos faciais ou fraturas dentoalveolares. Os achados apontam que homens e mulheres apresentam importantes diferenciais de vitimização em relação à violência interpessoal e trauma facial. O gênero da vítima, o gênero do agressor e o mecanismo de agressão podem exercer influência sobre os padrões de trauma facial.

Abstract The aims of this investigation were to describe the profile of men and women victims of violence and identify factors associated with the severity of facial trauma. A retrospective study was carried out from 762 records of victims attended at the Institute of Legal Medicine and Dentistry located in a metropolitan region of Northeastern Brazil. The dependent variable was type of facial trauma suffered by victims. Independent variables were the sociodemographic characteristics of victims, characteristics of aggressors and circumstances of violence. Descriptive, bivariate (c2 test) and multivariate statistics were made through logistic regression. Level of significance was set at p < 0.05. The mean age of victims was 29.78 years (SD=13.33). Based on the final regression model, male subjects [odds ratio (OR)=2.22, 95% CI=1.08-4.57, p=0.030], assaulted by other male subjects (OR=4.88; 95% CI=1.12-21.26; p=0.035) through instrument (OR=6.67; 95% CI=2.85-15.60; p<0,001) or mixed aggressions (OR=4.34; 95% CI=1.44-13.02; p=0.009) were more likely to exhibit facial bone fractures or dentoalveolar fractures. The findings highlight that men and women present important victimization differentials in relation to interpersonal violence and facial trauma. Victim’s gender, aggressor’s gender and mechanism of aggression may exert influence on facial trauma patterns.

Resumo O objetivo deste estudo foi descrever e analisar o histórico de dor de dente e seus fatores associados, entre adolescentes de escolas públicas de um município do Nordeste do Brasil. Realizou-se uma pesquisa observacional, descritiva, quantitativa e transversal, através da aplicação de quatro questionários junto a 458 adolescentes. Pela análise bivariada, a prevalência de dor de dente na vida foi alta entre os adolescentes de menor idade (76,9%; p = 0,004), que visitaram o Cirurgião-Dentista alguma vez (74,8%; p = 0,001) e que relataram medo frente ao atendimento odontológico (74,9%; p = 0,006). Todavia, nos últimos 6 meses, a prevalência de dor de dente foi baixa, na qual os adolescentes do sexo masculino (77,4%; p < 0,001) e de maior idade (73,1%; p = 0,031) relataram justamente não terem sentido dor. Quando da análise multivariada, a maior prevalência de dor de dente na vida se manteve entre os adolescentes de menor idade (76,9%; p = 0,003) e que relataram medo (74,9%; p = 0,006). A prevalência de dor de dente nos últimos 6 meses se manteve baixa na análise multivariada, entre os adolescentes do sexo masculino e de maior idade. Conclui-se que a prevalência de dor de dente na vida foi maior do que nos últimos 6 meses, havendo associação significativa com os fatores: sexo, idade, visita ao Cirurgião-Dentista e sensação de medo.

Abstract The aim of this study was to describe and analyze history of toothache and associated factors among adolescent students enrolled in public schools of a city in Northeastern Brazil. An observational, descriptive, quantitative and cross-sectional study was conducted through the application of 4 questionnaires with 458 adolescents. By bivariate analysis, the prevalence of toothache in life was higher among younger adolescents (76.9%; p = 0.004), who have visited the dentist at least once (74.8%; p = 0.001) and who reported fear (74.9%; p = 0.006). The occurrence of dental pain in the last 6 months was low, where male (77.4%; p = 0,001) and older adolescents (73.1%; p = 0.031) reported no occurrence of pain. Through multivariate analysis, the highest prevalence of dental pain in life remained among younger adolescents (76.9%; p = 0.003) and who reported dental fear (74.9%; p = 0.006). The prevalence of toothache in the last 6 months remained low through multivariate analysis, among male and older adolescents. It could be concluded that the prevalence of toothache in life was higher than in the last 6 months, showing significant association with gender, age, visit to the dentist and dental fear.

Resumo O objetivo deste estudo foi descrever e analisar o histórico de dor de dente e seus fatores associados, entre adolescentes de escolas públicas de um município do Nordeste do Brasil. Realizou-se uma pesquisa observacional, descritiva, quantitativa e transversal, através da aplicação de quatro questionários junto a 458 adolescentes. Pela análise bivariada, a prevalência de dor de dente na vida foi alta entre os adolescentes de menor idade (76,9%; p = 0,004), que visitaram o Cirurgião-Dentista alguma vez (74,8%; p = 0,001) e que relataram medo frente ao atendimento odontológico (74,9%; p = 0,006). Todavia, nos últimos 6 meses, a prevalência de dor de dente foi baixa, na qual os adolescentes do sexo masculino (77,4%; p < 0,001) e de maior idade (73,1%; p = 0,031) relataram justamente não terem sentido dor. Quando da análise multivariada, a maior prevalência de dor de dente na vida se manteve entre os adolescentes de menor idade (76,9%; p = 0,003) e que relataram medo (74,9%; p = 0,006). A prevalência de dor de dente nos últimos 6 meses se manteve baixa na análise multivariada, entre os adolescentes do sexo masculino e de maior idade. Conclui-se que a prevalência de dor de dente na vida foi maior do que nos últimos 6 meses, havendo associação significativa com os fatores: sexo, idade, visita ao Cirurgião-Dentista e sensação de medo.

Abstract The aim of this study was to describe and analyze history of toothache and associated factors among adolescent students enrolled in public schools of a city in Northeastern Brazil. An observational, descriptive, quantitative and cross-sectional study was conducted through the application of 4 questionnaires with 458 adolescents. By bivariate analysis, the prevalence of toothache in life was higher among younger adolescents (76.9%; p = 0.004), who have visited the dentist at least once (74.8%; p = 0.001) and who reported fear (74.9%; p = 0.006). The occurrence of dental pain in the last 6 months was low, where male (77.4%; p = 0,001) and older adolescents (73.1%; p = 0.031) reported no occurrence of pain. Through multivariate analysis, the highest prevalence of dental pain in life remained among younger adolescents (76.9%; p = 0.003) and who reported dental fear (74.9%; p = 0.006). The prevalence of toothache in the last 6 months remained low through multivariate analysis, among male and older adolescents. It could be concluded that the prevalence of toothache in life was higher than in the last 6 months, showing significant association with gender, age, visit to the dentist and dental fear.

Resumo O objetivo deste estudo foi avaliar as atitudes e as práticas dos profissionais da Estratégia Saúde da Família (ESF) quanto à abordagem aos usuários drogas no município de Campina Grande, Paraíba. Tratou-se de um estudo transversal e exploratório realizado com 126 médicos, enfermeiros e dentistas da Atenção Primária à Saúde (APS). As variáveis investigadas foram relacionadas a dados sociodemográficos, atuação profissional, atitudes e práticas sobre a abordagem aos usuários de drogas de acordo com o Plano Integrado de Enfrentamento ao Crack e outras Drogas. Foi realizada estatística descritiva e multivariada por meio da Análise de Correspondência Múltipla (ACM). A maioria dos profissionais era do sexo feminino (88,9%) e relatou questionar apenas às vezes quanto ao uso de drogas durante a anamnese (53,2%). Baseando-se na ACM, as variáveis com maior poder discriminatório para a dimensão 1 foram: tempo de formado (0,776), tempo de trabalho na APS (0,688), faixa etária (0,656); enquanto que para a dimensão 2 foram: categoria profissional (0,383) e se conhece os usuários de drogas em sua área de abrangência (0,166). Existem diferenças importantes nas atitudes e nas práticas acerca da abordagem dos usuários de drogas entre os profissionais.

Abstract The aim of this study was to evaluate the attitudes and practices of professionals of the Family Health Strategy regarding the approach to drug users in the municipality of Campina Grande. Paraíba. The cross-sectional and exploratory study carried out with 126 doctors. nurses and dentists of Primary Health Care (PHC). Variables investigated were related to sociodemographic data. professional profile. attitudes and practices about the approach to drug users according to the Integrated Plan to Confront Crack and Other Drugs. Descriptive and multivariate statistics were performed through Multiple Correspondence Analysis (MCA). Most professionals were female (88.9%) and reported questioning only sometimes about the use of drugs during the anamnesis (53.2%). Based on MCA results. variables with the greatest discriminatory power for dimension 1 were: training time (0.776). working time in the PHC (0.688). age group (0.656); while for dimension 2 were: professional category (0.383) and knowledge of drug users in their coverage area (0.166). There are important differences in attitudes and practices about the approach of drug users among professionals.

Resumo O objetivo deste estudo foi avaliar as atitudes e as práticas dos profissionais da Estratégia Saúde da Família (ESF) quanto à abordagem aos usuários drogas no município de Campina Grande, Paraíba. Tratou-se de um estudo transversal e exploratório realizado com 126 médicos, enfermeiros e dentistas da Atenção Primária à Saúde (APS). As variáveis investigadas foram relacionadas a dados sociodemográficos, atuação profissional, atitudes e práticas sobre a abordagem aos usuários de drogas de acordo com o Plano Integrado de Enfrentamento ao Crack e outras Drogas. Foi realizada estatística descritiva e multivariada por meio da Análise de Correspondência Múltipla (ACM). A maioria dos profissionais era do sexo feminino (88,9%) e relatou questionar apenas às vezes quanto ao uso de drogas durante a anamnese (53,2%). Baseando-se na ACM, as variáveis com maior poder discriminatório para a dimensão 1 foram: tempo de formado (0,776), tempo de trabalho na APS (0,688), faixa etária (0,656); enquanto que para a dimensão 2 foram: categoria profissional (0,383) e se conhece os usuários de drogas em sua área de abrangência (0,166). Existem diferenças importantes nas atitudes e nas práticas acerca da abordagem dos usuários de drogas entre os profissionais.

Abstract The aim of this study was to evaluate the attitudes and practices of professionals of the Family Health Strategy regarding the approach to drug users in the municipality of Campina Grande. Paraíba. The cross-sectional and exploratory study carried out with 126 doctors. nurses and dentists of Primary Health Care (PHC). Variables investigated were related to sociodemographic data. professional profile. attitudes and practices about the approach to drug users according to the Integrated Plan to Confront Crack and Other Drugs. Descriptive and multivariate statistics were performed through Multiple Correspondence Analysis (MCA). Most professionals were female (88.9%) and reported questioning only sometimes about the use of drugs during the anamnesis (53.2%). Based on MCA results. variables with the greatest discriminatory power for dimension 1 were: training time (0.776). working time in the PHC (0.688). age group (0.656); while for dimension 2 were: professional category (0.383) and knowledge of drug users in their coverage area (0.166). There are important differences in attitudes and practices about the approach of drug users among professionals.

ABSTRACT OBJECTIVE To evaluate the effect of the time and the sex of victims and perpetrators on the rates of family and community physical violence in a Brazilian municipality over seven years (2008–2014). METHODS We made a census analysis from non-fatal victims attended in the Forensic Institute of the Scientific Civil Police. The monthly and annual violence rates were calculated based on the population size of the municipality. Time series was evaluated by negative binomial regression models, based on the number of cases with population offset and considering the effect of the sex of victims and perpetrators. RESULTS A total of 3,324 cases of family and 4,634 cases of community violence were analyzed. There was a significant increase in family violence rates for female victims and male perpetrators. Family violence rates were always higher for female victims than for male and it was always lower for female perpetrators than for male (p < 0.001). There was a lower risk of community violence for male victims after 2013 and a decrease of aggression perpetrated by men over time. Men and women were similarly affected by community violence; however, the perpetrators were more frequently men. CONCLUSIONS The results indicate a trend of increasing female victims in the family violence, mainly perpetrated by men. The reduction in community violence rates could be the result of policies to reduce crime.

ABSTRACT OBJECTIVE To evaluate the effect of the time and the sex of victims and perpetrators on the rates of family and community physical violence in a Brazilian municipality over seven years (2008–2014). METHODS We made a census analysis from non-fatal victims attended in the Forensic Institute of the Scientific Civil Police. The monthly and annual violence rates were calculated based on the population size of the municipality. Time series was evaluated by negative binomial regression models, based on the number of cases with population offset and considering the effect of the sex of victims and perpetrators. RESULTS A total of 3,324 cases of family and 4,634 cases of community violence were analyzed. There was a significant increase in family violence rates for female victims and male perpetrators. Family violence rates were always higher for female victims than for male and it was always lower for female perpetrators than for male (p < 0.001). There was a lower risk of community violence for male victims after 2013 and a decrease of aggression perpetrated by men over time. Men and women were similarly affected by community violence; however, the perpetrators were more frequently men. CONCLUSIONS The results indicate a trend of increasing female victims in the family violence, mainly perpetrated by men. The reduction in community violence rates could be the result of policies to reduce crime.

RESUMO Objetivo: Traçar o perfil dos pacientes internados com trauma de face em um hospital localizado em região metropolitana do Nordeste do Brasil. Métodos: Tratou-se de estudo transversal e exploratório. Um total de 244 casos atendeu aos critérios de elegibilidade, sendo incluídos na amostra. As variáveis estudadas incluíram características sociodemográficas das vítimas, etiologia, tipos de traumas, modalidades de tratamento, tempo de internação e trimestre de atendimento. Foi feita estatística descritiva e análise de cluster. Resultados: A média de idade dos pacientes foi 31,16 anos (DP = 15,17 anos) e o tempo médio de internação foi de 6,32 dias (DP = 7,75 dias). Verificou-se a formação automática de quatro clusters com perfis distintos de pacientes. As variáveis que mais contribuíram para a diferenciação externa entre os clusters foram: tempo de internação (p < 0,001), etiologia (p < 0,001), tipo do trauma facial (p < 0,001), presença de trauma associado (p < 0,001), tipo de tratamento (p < 0,001) e trimestre de atendimento (p < 0,001). Conclusão: A maioria dos pacientes eram homens, vítimas de acidentes de trânsito, que apresentaram fratura do complexo zigomático, submetidos a tratamento cirúrgico. Nível de Evidência III, Estudo Retrospectivo.

ABSTRACT Objective: To describe the profile of patients with facial trauma admitted in a hospital located in a metropolitan area of Northeast Brazil. Methods: A cross-sectional and exploratory study was performed. A total of 244 cases were in agreement with the eligibility criteria. The variables include the sociodemographic characteristics of patients, etiology, type of trauma, treatment modalities, length of stay in a hospital and quarter of care. Descriptive statistics and Cluster Analysis were performed. Results: The average age of patients was 31.16 years (SD = 15.17 years) and average hospitalization was 6.32 days (SD = 7.75 days). It was verified the automatic formation of four clusters with different profiles of patients. The variables which most contributed to the external differentiation between clusters were: length of stay in a hospital (p <0.001), etiology (p <0.001), type of facial trauma (p <0.001), presence of associated trauma (p <0.001), treatment modalities (p <0.001) and quarter of care (p <0.001). Conclusion: The most of patients were men, victims of traffic accidents, which suffered fracture of zygomatic complex and underwent surgery. Level of Evidence III, Retrospective Study.

A pleiotropic response to the calpain inhibitor MDL28170 was detected in the tomato parasite Phytomonas serpens. Ultrastructural studies revealed that MDL28170 caused mitochondrial swelling, shortening of flagellum and disruption of trans Golgi network. This effect was correlated to the inhibition in processing of cruzipain-like molecules, which presented an increase in expression paralleled by decreased proteolytic activity. Concomitantly, a calcium-dependent cysteine peptidase was detected in the parasite extract, the activity of which was repressed by pre-incubation of parasites with MDL28170. Flow cytometry and Western blotting analyses revealed the differential expression of calpain-like proteins (CALPs) in response to the pre-incubation of parasites with the MDL28170, and confocal fluorescence microscopy confirmed their surface location. The interaction of promastigotes with explanted salivary glands of the insect Oncopeltus fasciatus was reduced when parasites were pre-treated with MDL28170, which was correlated to reduced levels of surface cruzipain-like and gp63-like molecules. Treatment of parasites with anti-Drosophila melanogaster (Dm) calpain antibody also decreased the adhesion process. Additionally, parasites recovered from the interaction process presented higher levels of surface cruzipain-like and gp63-like molecules, with similar levels of CALPs cross-reactive to anti-Dm-calpain antibody. The results confirm the importance of exploring the use of calpain inhibitors in studying parasites’ physiology.

RESUMO: Objetivo: Descrever o perfil da violência contra mulheres em diferentes ciclos de vida, de acordo com as características sociodemográficas das vítimas e dos agressores. Métodos: Estudo transversal e exploratório realizado com base em 1.388 registros de ocorrências, durante período de quatro anos, em uma região metropolitana do Nordeste do Brasil. A variável dependente foi o tipo de agressão sofrido pelas vítimas. As variáveis independentes foram as características sociodemográficas das vítimas e dos agressores. A análise estatística incluiu o teste χ2 (p < 0,05) e a análise de árvore de decisão, por meio do algoritmo Chi-squared Automatic Interaction Detector (CHAID). Resultados: Os casos de agressão física (n = 644) foram os mais comuns, seguidos de ameaça (n = 415) e agressão verbal (n = 285). Os perfis da violência puderam ser explicados pela relação entre vítimas e agressores (p < 0,001) e faixa etária das vítimas (p = 0,026 em Nó 1; p = 0,019 em Nó 3). Conclusão: Foi observado que mulheres em diferentes fases da vida apresentam mais exposição a diferentes tipos de violência.

ABSTRACT: Objective: The aim of this study was to describe the profile of violence against women in different life cycles, according to the sociodemographic characteristics of the victims and offenders. Methods: A cross-sectional and exploratory study was performed based on 1,388 police reports during a four-year period, in a metropolitan area of Northeast Brazil. The dependent variable was the type of aggression suffered by the victims. The independent variables were sociodemographic characteristics of the victims and offenders. Statistical analysis included the χ2 test (p < 0.05) and the decision tree analysis, through the Chi-squared Automatic Interaction Detector (CHAID) algorithm. Results: Cases of physical abuse (n = 644) were the most common, followed by threat (n = 415) and verbal aggression (n = 285). The violence profiles could be explained by the relationship between victims and offenders (p < 0.001) and age of the victims (p = 0.026 in Node 1; p = 0.019 in Node 3). Conclusion: It was observed that women in different stages of life are more exposed to different types of violence.

RESUMO: Objetivo: Descrever o perfil da violência contra mulheres em diferentes ciclos de vida, de acordo com as características sociodemográficas das vítimas e dos agressores. Métodos: Estudo transversal e exploratório realizado com base em 1.388 registros de ocorrências, durante período de quatro anos, em uma região metropolitana do Nordeste do Brasil. A variável dependente foi o tipo de agressão sofrido pelas vítimas. As variáveis independentes foram as características sociodemográficas das vítimas e dos agressores. A análise estatística incluiu o teste χ2 (p < 0,05) e a análise de árvore de decisão, por meio do algoritmo Chi-squared Automatic Interaction Detector (CHAID). Resultados: Os casos de agressão física (n = 644) foram os mais comuns, seguidos de ameaça (n = 415) e agressão verbal (n = 285). Os perfis da violência puderam ser explicados pela relação entre vítimas e agressores (p < 0,001) e faixa etária das vítimas (p = 0,026 em Nó 1; p = 0,019 em Nó 3). Conclusão: Foi observado que mulheres em diferentes fases da vida apresentam mais exposição a diferentes tipos de violência.

ABSTRACT: Objective: The aim of this study was to describe the profile of violence against women in different life cycles, according to the sociodemographic characteristics of the victims and offenders. Methods: A cross-sectional and exploratory study was performed based on 1,388 police reports during a four-year period, in a metropolitan area of Northeast Brazil. The dependent variable was the type of aggression suffered by the victims. The independent variables were sociodemographic characteristics of the victims and offenders. Statistical analysis included the χ2 test (p < 0.05) and the decision tree analysis, through the Chi-squared Automatic Interaction Detector (CHAID) algorithm. Results: Cases of physical abuse (n = 644) were the most common, followed by threat (n = 415) and verbal aggression (n = 285). The violence profiles could be explained by the relationship between victims and offenders (p < 0.001) and age of the victims (p = 0.026 in Node 1; p = 0.019 in Node 3). Conclusion: It was observed that women in different stages of life are more exposed to different types of violence.

Antecedentes: la metionina es esencial para el mantenimiento, crecimiento y desarrollo de las plumas. El suministro de metionina durante la fase de crecimiento puede influir en factores tales como el peso corporal a la madurez sexual y el tamaño del huevo. Objetivo: evaluar los efectos de varias proporciones de metionina + cistina digestibles y lisina digestible en la dieta de codornices japonesas en fase de crecimiento (1 a 40 días de edad) y su efecto en la producción inicial de huevos (41 a 110 días de edad). Métodos: se utilizaron 1.000 codornices japonesas de un día de edad, en un diseño aleatorizado con cinco proporciones de (metionina + cistina) digestible/lisina digestible, con 10 replicaciones y 20 aves por unidad experimental. La dieta basal formulada se complementó con cinco niveles de DL-metionina en sustitución del ácido glutámico. Resultados: el peso de los animales al día 40, la ganancia de peso hasta el día 40, la ingesta de alimento, el peso de la carcasa, la deposición de grasa y proteína corporal, la ingesta de metionina + cistina y la viabilidad de las aves en la fase de crecimiento apresentaram uma tendência linear. Se observó un efecto cuadrático para conversión de alimento y uniformidad a los 40 días de edad y el porcentaje de plumas no varió. Durante el período de producción de huevos hubo un aumento lineal para consumo de alimento y ganancia de peso de las aves. Não foram observados outros efeitos proporções em relação a outras variáveis. Conclusión: una proporción de 0,73 entre metionina + cistina digestible/lisina digestible en la fase de crecimiento provee un desarrollo uniforme y un rendimiento satisfactorio en la producción de huevos de la codorniz japonesa.

Background: methionine is considered essential for maintenance, growth, and feather development. Methionine supply during the growth phase can influence the weight at sexual maturity and egg size. Objective: to evaluate the effects of several digestible methionine + cystine/digestible lysine ratios for growing Japanese quails (1 to 40 days of age) with repercussions on the early stage of production (41 to 110 days of age). Methods: a total of 1,000 one-day-old Japanese quails were randomly distributed to five digestible (methionine + cystine)/digestible lysine ratios, with 10 replicates and 20 birds per experimental unit. A basal diet formulated to meet all nutrient requirements was added with graded levels of DL-methionine replacing glutamic acid. Results: weight of the birds at 40 days, weight gain until 40 days, feed intake, carcass weight, fat, and body protein deposition, methionine + cystine intake and birds viability in the growing phase presented a linear trend. A quadratic effect was observed for feed conversion and uniformity at 40 days of age, and percentage of feathers did not vary. A linear increase occurred in the laying phase for feed intake and weight gain of the birds. No effects of the assessed ratios were observed on the other variables. Conclusion: a 0.73 ratio of digestible (methionine + cystine) to digestible lysine in the growing phase provided uniform growth and satisfying performance of Japanese quails during the laying phase.

Antecedentes: a metionina é considerada essencial para manutenção, crescimento e desenvolvimento das penas nas codornas. O fornecimento nutricional de metionina durante a fase de crescimento pode influenciar fatores como peso corporal para maturidade sexual e tamanho do ovo. Objetivo: avaliar os efeitos entre metionina + cistina digestível e lisina digestível na dieta para codornas japonesas na fase de crescimento (1 a 40 dias de idade) com repercussão na fase inicial de postura (41 a 110 dias de idade). Métodos: foram utilizadas 1.000 codornas japonesas com 1 dia de idade, distribuídas em delineamento inteiramente casualizado com 5 relações entre (metionina mais cistina) digestível/lisina digestível, 10 repetições e 20 aves por unidade experimental. Foi formulada uma ração basal suplementada com cinco níveis de DL-metionina em substituição ao ácido glutâmico. Resultados: o peso corporal das aves até os 40 dias, ganho de peso até os 40 dias, consumo de ração, peso de carcaça, deposição de gordura e de proteína corporal, consumo de metionina + cistina e viabilidade das aves na fase de crescimento houve aumento linear para. Efeito quadrático foi observado para conversão alimentar e uniformidade aos 40 dias e a porcentagem de penas não variou. Na fase de postura, ocorreu aumento linear para consumo de ração e ganho de peso das aves. Conclusão: a relação metionina + cistina e lisina digestível de 0,73 na dieta de recria proporcionou crescimento uniforme e desempenho satisfatório de codornas japonesas na fase de postura.

<p>O experimento foi realizado para estimar a exigência nutricional de sódio (Na) para codornas japonesas em postura. Foram utilizadas 245 codornas japonesas, com 187 dias de idade, peso de 189,4 <underline>+</underline> 6,1 g e taxa de produção de ovos de 91,05 <underline>+</underline> 5,5 %. As aves foram distribuídas em delineamento experimental inteiramente casualizado, constituído por cinco rações e sete repetições. Foram formuladas cinco rações experimentais à base de milho e farelo de soja, com cinco níveis de Na (0,10; 0,15; 0,20; 0,25 e 0,30%). Foram analisados: consumo de ração, produção de ovos por ave ao dia, por ave alojada, de ovos comercializáveis, de ovos viáveis por ave ao dia, peso do ovo, massa de ovos, conversão alimentar por massa de ovos e por dúzia de ovos, componentes dos ovos (gema (g e %), albúmen (g e %) e casca (g e %), variação de peso corporal, viabilidade das aves e gravidade específica. Não foi verificado efeito (P>0,05) para nenhum dos parâmetros estudados. Sintomas de deficiência de sódio como inapetência, redução da taxa de crescimento, produção e apetite depravado não foram observados, demonstrando que o menor nível de sódio utilizado, 0,10%, não foi prejudicial às aves. A suplementação de 0,10% de sódio na ração, correspondente ao consumo diário de 26,1 mg de Na por ave foi suficiente para proporcionar satisfatório desempenho produtivo e qualidade dos ovos de codornas japonesas.</p>

<p>The experiment was conducted to estimate the nutritional requirement of sodium (Na) for laying Japanese quails. Were used 245 Japanese quails, with 187 days old, weight of 189.4 <underline>+</underline> 6.1 g and egg production rate of 91.05 <underline>+</underline> 5.5%. Birds were distributed in a completely randomized design, consisting of five diets and seven replicates. Five experimental diets were formulated based on corn and soybean meal, with five levels of Na (0.10, 0.15, 0.20, 0.25 and 0.30%). Were examined: feed intake, egg production per bird day, egg production per hen housed, commercial eggs, viable eggs per bird day, egg weight, egg mass, feed conversion by egg mass and per dozen eggs, components eggs (yolk, albumen and shell), body weight variation, viability of birds and specific gravity. There were no differences (P>0.05) for all parameters studied. Symptoms of deficiency as inappetence, reduction in the growth rate and depraved appetite were not observed in this study, demonstrating that the lower level of Na used, 0.10%, was not adverse to birds. Supplementation of 0.10% Na in diet of the birds, corresponding to a daily intake of 26.1 mg / bird was enough to provide good performance and egg quality of Japanese quails.</p>