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RESUMO: Propõe-se uma relação entre a reificação do corpo e o processo de imaginarização. Imaginarização é uma noção apenas aludida na obra de Lacan. Propõe-se uma leitura acerca de apresentações clínicas nas quais prevalece um estado depressivo neurótico. Hipótese: nessas situações, o sujeito parece reduzir-se ao próprio corpo, como resposta a certas exigências da cultura contemporânea. Busca-se lançar luz sobre o automatismo do gozo do corpo no circuito pulsional. Por meio da noção de imaginarização, destaca-se um enquadramento particular que o sujeito dá ao gozo, ao invés de posicionar-se como faltante na relação com o Outro. RESUMO Propõese Propõe se imaginarização Lacan neurótico Hipótese situações reduzirse reduzir contemporânea Buscase Busca pulsional destacase destaca posicionarse posicionar Outro

Abstract: We propose a relationship between the reification of the body and the process of imaginarization. Imaginarization is a notion only alluded to in Lacan’s work. We propose a reading about clinical presentations in which a neurotic depressive state prevails. The hypothesis: in these situations, the subject seems to be reduced to his own body, in response to certain demands of contemporary culture. Thus, we seek to shed light on the automatism of the jouissance of the body in the drive circuit. Through the notion of imaginarization, it is possible to highlight a particular framework that the subject gives to jouissance, instead of positioning themselves as lacking in the relationship with the Other. Abstract imaginarization Lacans Lacan s work prevails hypothesis situations culture Thus circuit Other

https://doi.org/10.1590/1809-44142022003002

Giftedness and ADHD: A systematic literature review
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Soares Coutinho-Sout, Waleska Karinne

; de Souza Fleith, Denise

Revista de Psicología (PUCP)

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jul 2022, Volume 40 N. 2 Pages 1175 - 1211

Abstract The purpose of this study was to examine the scientific production of empirical articles regarding twice exceptionality - giftedness/ADHD - through a systematic review. The search was carried out in the Portal de Periódicos Capes, SciELO, and PePSIC databases, considering the publications between 2011 and 2021. The terms giftedness, high abilities, ADHD, twice exceptionality, and their counterparts in Portuguese were used as descriptors. We selected 27 articles based on pre-established inclusion criteria. Six categories of studies were identified: socio-emotional factors, interpersonal relationships, identification, inattention and hyperactivity, intelligence quotient, and educational support practices. The conclusion was that by having their individual needs met and school community support, gifted students with ADHD can academically succeed, have a positive self-concept and good interpersonal relationships.

Résumé Nous examinons, à travers une revue systématique de la littérature, la production d’articles empiriques sur l’exceptionnalité - surdouance/TDAH. La recherche a été effectuée dans les bases Capes, SciELO et PePSIC, en considérant les publications entre 2011 et 2021. Les descripteurs talent, douance, TDAH et double exceptionnalité ont été utilisés. Vingt-sept articles ont été sélectionnés a partir de critères d’inclusion. Six catégories d’études ont été identifiées: aspects socio-émotionnels, relations interpersonnelles, identification, inattention et hyperactivité, quotient intellectuel et pratiques de soins éducatifs. On a conclu que les surdoués atteints de TDAH peuvent réussir à l’école, avoir une image de soi positive et de bonnes relations interpersonnelles s’ils sont pris en charge selon leurs besoins individuels et avec le soutien de la communauté scolaire.

Resumen Este estudio examinó, a través de una revisión sistemática de literatura, la producción científica de artículos empíricos sobre doble excepcionalidad - sobredotación/TDAH. La búsqueda se realizó en las bases de datos Capes, SciELO y PePSIC, considerando publicaciones entre 2011 y 2021. Se usaron los descriptores altas capacidades, TDAH y doble excepcionalidad y sus equivalentes en inglés. Con base en los criterios de inclusión preestablecidos, se seleccionaron 27 artículos. Fueron identificadas seis categorías de estudios: aspectos socioemocionales, relaciones interpersonales, identificación, desatención y hiperactividad, cociente intelectual y prácticas educativas de apoyo. Se concluyó que sobredotados con TDAH pueden presentar éxito académico, autoconcepto positivo y buenas relaciones interpersonales si son atendidos de acuerdo a sus necesidades individuales y con apoyo de la comunidad escolar.

Resumo Este estudo examinou, por meio de uma revisão sistemática da literatura, a produção científica de artigos empíricos acerca da dupla excepcionalidade - superdotação/TDAH. A busca foi realizada nas bases de dados Portal de Periódicos Capes, SciELO e PePSIC, considerando as publicações entre 2011 e 2021. Utilizou-se os descritores superdotação, altas habilidades, TDAH e dupla excepcionalidade, bem como seus correspondentes em inglês. Foram selecionados 27 artigos, a partir dos critérios de inclusão pré-estabelecidos. Identificaram-se seis categorias de estudos: aspectos socioemocionais, relações interpessoais, identificação, desatenção e hiperatividade, quociente de inteligência e práticas educativas de atendimento. Concluiu-se que superdotados com TDAH podem apresentar sucesso acadêmico, autoconceito positivo e bom relacionamento interpessoal se forem atendidos conforme suas necessidades individuais e com apoio da comunidade escolar.

https://doi.org/10.18800/psico.202202.019

A noção lacaniana de imaginarização: a clínica psicanalítica e seus desdobramentos no social
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Bacelar, Joyce

; Coutinho, Denise

Revista Latinoamericana de Psicopatologia Fundamental

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jan 2022, Volume 25 N. 1 Pages 83 - 105

Este ensaio teórico-clínico aborda a noção de imaginarização, apenas mencionada por Lacan em três passagens de sua obra, a fim de compreender algumas manifestações clínicas e processos de segregação contemporâneos. A hipótese é de que a imaginarização é o cerne de uma operação que pode conduzir o sujeito a um modo específico e fixado de gozo. A questão principal é o tipo de relação com o objeto a e o que pode derivar desse processo no que diz respeito à economia de gozo. Aborda-se o discurso contemporâneo, sublinhando modos de gozo que podem derivar desse processo. Como se trata de manifestações sintomáticas contemporâneas na clínica, demonstram-se derivações do singular (registro por excelência da clínica psicanalítica) ao particular, no engate do sujeito com o laço social.

This theoretical-clinical essay discusses the notion of imaginarization, mentioned by Lacan in only three passages of his oeuvre, to understand certain contemporary clinical manifestations and segregation processes. It hypothesizes that imaginarization is at the core of an activity that can lead the subject to a fixed and specific mode of jouissance. The main question is the type of relationship with object a and what can be derived from this process regarding the economy of jouissance. Contemporary discourse is considered, emphasizing the modes of jouissance that can emerge from this process. In dealing with contemporary symptomatic manifestations in the clinic, the texts point to derivations from the singular (a quintessential register of the psychoanalytic clinic) to the particular, in the subject’s relations with social discourse.

Este ensayo teórico-clínico discute la noción de imaginarización mencionada por Lacan solo en tres momentos de su obra, con el fin de comprender algunas manifestaciones clínicas y procesos de segregación contemporáneos. Se plantea la hipótesis de que la imaginarización está en el centro de una operación que puede llevar al sujeto a un modo de goce específico y fijo. La cuestión principal es el tipo de relación con el objeto a y lo qué se puede derivar de este proceso con respecto a la economía del goce. Se aborda el discurso contemporáneo enfatizando los modos de goce que pueden derivarse de este proceso. Dado que son manifestaciones sintomáticas contemporáneas en la clínica, se evidencian las derivaciones del singular (registro por excelencia de la clínica psicoanalítica) a lo particular, en la relación del sujeto con el lazo social.

Cet essai théorico-clinique traite du concept d’imaginarisation, évoquée par Lacan dans trois passages de son œuvre, afin de comprendre quelques manifestations cliniques et processus de ségrégation contemporains. Nous supposons que l’imaginarisation est au cœur d’une opération qui peut conduire le sujet à un mode de jouissance spécifique et figé. La question principale est le type de relation avec l'objet a et ce que l’on peut déduire de ce processus concernant l’économie de la jouissance. Nous discutons du discours contemporain, nous concentrant sur les modes de jouissance qui peuvent résulter de ce processus. En traitant des manifestations symptomatiques contemporaines dans la clinique, nous démontrons des dérivations du singulier (registre par excellence de la clinique psychanalytique) au particulier, dans le rapport du sujet au lien social.

https://doi.org/10.1590/1415-4714.2022v25n1p83.5

Cancer chemopreventive and antioxidant activities of seed, skin, and pulp of Maximo hybrid grapes (IAC 138-22) at five different ripening stages
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Freire, Débora Rigamonti Gomes Cruz

; Cassiano, Camile Zanichelli da Costa

; Soares, Karla Lírio

; Lemos, Mayara Fumiere

; Pimentel-Schmitt, Elisângela Flávia

; Fronza, Marcio

; Endringer, Denise Coutinho

; Scherer, Rodrigo

Ciência Rural

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2022, Volume 52 N. 3 elocation e20200962

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO: O objetivo deste estudo foi avaliar a composição e as atividades quimiopreventiva de câncer e antioxidante da semente, polpa e casca de uvas híbridas Maximo (IAC 138-22) colhidas em diferentes estágios de maturação. Os teores de compostos fenólicos totais, antocianinas e taninos foram determinados a partir dos extratos etanólicos. O conteúdo de fenólicos e taninos totais foi determinado pelo método de Folin-Ciocaulteau, e o teor de antocianinas totais foi determinado pelo método do pH diferencial. A atividade antioxidante foi avaliada por diferentes métodos químicos, e a viabilidade celular (macrófagos e melanomas), e atividade quimiopreventiva de câncer foi testada em culturas de células por ensaio de indução de quinona redutase, ensaio de atividade inibidora de NF-κB induzido por TNF-α e ensaio de atividade inibidora de aromatase. A uva híbrida apresentou alto teor de fenólicos nas sementes e na casca, teor que reduziu significativamente com o amadurecimento. Os resultados mostraram que o amadurecimento dos frutos afetou significativamente a composição e as atividades antioxidantes e quimiopreventivas de câncer. Com exceção do teor de antocianinas, os resultados mais significativos foram observados para as sementes verdes, com o estádio mais verde apresentando os melhores resultados. As sementes verdes apresentaram a maior atividade antioxidante, mesmo quando comparadas ao resveratrol livre. Na avaliação da atividade quimiopreventiva do câncer, as sementes verdes mostraram capacidade de inibir a atividade do NF-κB e da aromatase, fatores importantes para o estágio inicial do desenvolvimento do câncer. Além disso, nenhum extrato apresentou atividade citotóxica. Portanto, as sementes verdes desta uva apresentam resultados promissores dadas as fortes atividades antioxidantes e quimiopreventivas do câncer aqui confirmadas, sugerindo efeitos benéficos à saúde.

ABSTRACT: This study evaluated the composition and the cancer chemopreventive and antioxidant activities of the seed, skin, and pulp of Maximo hybrid grapes (IAC 138-22) harvested at different ripening stages. The content of total phenolic compounds and tannins were determined by the Folin-Ciocaulteau method, and total anthocyanins were determined using the differential pH method. Different chemical methods assessed the antioxidant activity. Cell viability (macrophage and melanoma skin cancer) and cancer chemopreventive activity were tested in cell lines by quinone reductase induction assay, TNF-α-induced NF-κB inhibitory activity assay, and aromatase inhibitory activity assay. The hybrid grape had high phenolic contents in both seeds and skin, significantly reduced upon ripening. The results showed that fruit ripening significantly affected both the composition and the antioxidant and cancer chemopreventive activities. Except for the anthocyanin content, the most significant results were observed for green seeds, with the greenest stage showing the best results. The green seeds showed the highest antioxidant activity, even when compared to free resveratrol. In the assessment of cancer chemopreventive activity, the green seeds showed the ability to inhibit N-FκB and aromatase activity, important factors for the early stage of cancer development. Besides, no extracts showed cytotoxicity. Therefore, this grape’s green seeds showed strong antioxidant and cancer chemopreventive activities confirmed herein, suggesting beneficial health effects.

https://doi.org/10.1590/0103-8478cr20200962 119 downloads

Pharmaceutical services in primary health care: dissatisfaction among users, managers and pharmacists
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Cruz, Manuela Martins

; Heringer, Karla Oliveira dos Santos Cassaro

; Lyrio, Cristiane

; Brasil, Girlandia Alexandre

; Lima, Ewelyne Miranda de

; Endringer, Denise Coutinho

; Lenz, Dominik

; Rezende, Ana Maria Bartels

; Andrade, Tadeu Uggere de

Brazilian Journal of Pharmaceutical Sciences

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2022, Volume 58 elocation e18849

Abstract: En | Text: En | PDF: En

Abstract To assess the performance indicators for pharmaceutical services (PS) in primary health care (PHC), the level of satisfaction with pharmacy services among users and managers / pharmacists’ impressions in relation to the findings were evaluated. The study used mixed methods, including a retrospective and descriptive study of the performance indicators for PS in PHC, an observational study on the level of satisfaction and a qualitative study of users’ perception of pharmacy services at Health Units. Managers and pharmacists’ impressions of the study results were also collected. Only 44.4% of pharmacies had a full-time pharmacist. From the establishments visited, 5.3% did not have an air-conditioned environment, and only 33.3% of the items essential to the Good Practices of Storage of Medicines and Supplies criteria were fulfilled. Although 77.9% of the prescribed medicines were dispensed, it did not reach the 80% standard. The satisfaction level of users was 3.2±0.6, indicating dissatisfaction with pharmacies’ services. By means of an evaluation of each item within the questionnaire, it was possible to observe that variables related to pharmaceutical care presented low scores in relation to other domains, thus evidencing the fragility of the pharmaceutical- patient relationship in users’ perception. Managers and pharmacists suggested that these results were related to the inadequate physical infrastructure of pharmacies, work overload, lack of recognition and undervaluation of pharmacists, lack of interaction within the PHC team, high turnover of pharmacists, and lack of PS prioritization by the administration. PS in PHC has structural and organizational weaknesses that require changes. In general, users are dissatisfied with pharmacies’ services, especially with pharmaceutical care.

https://doi.org/10.1590/s2175-97902020000318849

An approach fuzzy for self-assessing in micro and small building companies
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De França Magalhães, Welton

; Coutinho de Melo, Fagner José

; Dumke de Medeiros, Denise

Revista ingeniería de construcción

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dec 2021, Volume 36 N. 3 Pages 322 - 341

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

Abstract: Due to increased competition enterprises have sought alternatives to improve their processes and increase the quality of their products and services. The enterprises of construction sector are related to the buildings construction. They have adopted Quality Management System (QMS) to improve their processes and to fill the demands of the market. Among the existing QMS, the Brazilian Program of Habitat Quality and Productivity (PBQP-H/Siac) has distinguished itself by offering benefits that are favorable to the enterprises in this segment. However, unlike medium and large enterprises, the Micro and Small enterprises (MSEs) have limited financial resources, lack on quality management, and others obstacles. MSEs have fitted their quality implementation to match with the larger construction enterprises, to better competition and to get opportunities in the market. Because of this, the present paper proposes an approach to self-evaluation requirements of PBQP-H/Siac, using fuzzy logic as a measurement tool. The fuzzy logic will formalized the assessed requirement, providing better definition on decision making. The approach exposed as a simulation based on real case to demonstrate their applicability. As a result the approach determines the degree of formalization of the desired level.

Resumen: Debido al aumento de la competencia, las empresas han buscado alternativas para mejorar sus procesos y aumentar la calidad de sus productos y servicios. Las empresas del sector de la construcción están relacionadas con la construcción de edificios. Han adoptado el Sistema de Gestión de Calidad (SGC) para mejorar sus procesos y satisfacer las demandas del mercado. Entre los SGC existentes, el Programa Brasileño de Calidad y Productividad del Hábitat (PBQP-H/Siac) se ha distinguido por ofrecer beneficios que son favorables para las empresas de este segmento. Sin embargo, a diferencia de las medianas y grandes empresas, las micro y pequeñas empresas (MYPE) tienen recursos financieros limitados, falta de gestión de calidad y otros obstáculos. Las PyMEs han ajustado su implementación de calidad para que coincida con las empresas de construcción más grandes, para una mejor competencia y para obtener oportunidades en el mercado. Debido a esto, el presente documento propone un enfoque para los requisitos de autoevaluación de PBQP-H/Siac, utilizando la lógica difusa como herramienta de medición. La lógica difusa formalizará el requisito evaluado, proporcionando una mejor definición en la toma de decisiones. El enfoque expuesto como una simulación basada en un caso real para demostrar su aplicabilidad. Como resultado, el enfoque determina el grado de formalización del nivel deseado.

https://doi.org/10.7764/ric.00006.21 22 downloads

Long-acting insulin in a public health system: analysis of compliance with clinical protocol in public pharmacies
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Andrade, Tadeu Uggere de

; Moreira, Fabrício Soares

; Cassaro, Karla Oliveira dos Santos

; Cruz, Manuela Martins

; Brasil, Girlandia Alexandre

; Lima, Ewelyne Miranda de

; Lenz, Dominik

; Endringer, Denise Coutinho

Ciência & Saúde Coletiva

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jun 2021, Volume 26 N. 6 Pages 2301 - 2310

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Diabetes mellitus (DM) é uma doença crônica marcada por níveis sanguíneos elevados de glicose. O controle do DM envolve dieta adequada, exercícios físicos, medicamentos e monitoramento dos níveis sanguíneos de glicose e de hemoglobina glicada (HbA1c). Trata-se de um estudo retrospectivo do processo de dispensação de análogos de insulina de ação prolongada a usuários com diabetes (tipos 1 e 2) cadastrados em farmácias públicas de alto custo do sistema público de saúde de um estado do Sudeste do Brasil, que buscou avaliar o cumprimento dos critérios do protocolo clínico para fornecimento desses análogos. Dos 987 usuários cadastrados no serviço de saúde, 315 preencheram os critérios de inclusão. A avaliação dos processos de dispensação dos análogos de insulina de ação prolongada revelou que os critérios de inclusão, exclusão e suspensão do protocolo dos análogos de insulina eram parcialmente cumpridos. Além disso, não houve diferença entre os níveis inicial e final de glicemia em jejum e HbA1c. Conclui-se que os critérios estabelecidos para dispensação de análogos de insulina de ação prolongada foram parcialmente cumpridos pelas farmácias, comprometendo o uso racional dos análogos. Os achados podem impactar diretamente no custo de manutenção do serviço público de saúde e na saúde do usuário.

Abstract Diabetes mellitus (DM) is a chronic disease marked by elevated blood glucose levels. Controlling DM involves adequate diet, physical exercises, medicines and monitoring the blood glucose and glycated hemoglobin (HbA1c) levels. This was a retrospective study of the process of dispensing long-acting insulin analogues to users with diabetes (types 1 and 2) who were registered at high-cost public pharmacies in public health system in a southeast state of Brazil, that sought to evaluate the fulfillment of the criteria of all the clinical protocol to provide these analogs. Of the 987 users registered in the health service, 315 met the inclusion criteria for the study. The evaluation of the dispensing processes of the long-acting insulin analogues revealed that the inclusion, exclusion, and suspension criteria of the protocol related with these insulin analogues were in some extend only partially fulfilled. Additionally, there was no difference between the initial and final fasting glycemic and HbA1c levels. It is concluded that the established criteria for dispensing long-acting insulin analogues were partly fulfilled by pharmacies, compromising the rational use of these analogues. It can directly impact the cost of maintaining the public health service and users’ health.

https://doi.org/10.1590/1413-81232021266.06592019 159 downloads

Long-acting insulin in a public health system: analysis of compliance with clinical protocol in public pharmacies
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Andrade, Tadeu Uggere de

; Moreira, Fabrício Soares

; Cassaro, Karla Oliveira dos Santos

; Cruz, Manuela Martins

; Brasil, Girlandia Alexandre

; Lima, Ewelyne Miranda de

; Lenz, Dominik

; Endringer, Denise Coutinho

Ciência & Saúde Coletiva

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jun 2021, Volume 26 N. 6 Pages 2301 - 2310

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

https://doi.org/10.1590/1413-81232021266.06592019

10.

Supply of enteral diets in the Espirito Santo state public health system in Brazil
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Pedroni, Narjara Laranja de Souza

; Lenz, Dominik

; Andrade, Tadeu Uggere de

; Endringer, Denise Coutinho

Nutrición Hospitalaria

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feb 2021, Volume 38 N. 1 Pages 23 - 28

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

Abstract Background: Brazil includes food as a social right, making the State responsible to the courts for the sufficient and adequate supply of enteral food. Objectives: to evaluate the supply of enteral diets in pharmacies in the state of Espirito Santo. Methods: to do this, we used the forms filled out by patients or legal representatives, containing medical records, to analyze the nutritional and social profiles of the users over two years, and the compliance of the administrative processes with the ordinance that instituted enteral food supplies was verified. Results: the sample was comprised of 204 patients receiving enteral nutrition, and the administrative procedures required to supply these patients were surveyed in seven (7/9) pharmacies. The data showed that the most common group was that of women (51 %), who were white (51 %), legally represented (91 %), and 73.5 years old (11 to 109 years). Information regarding missing anthropometric data, use of terms and calculations for obtaining enteral food other than those recommended, incomplete documents, alterations to the physical examinations suggestive of error, and nonobservance of inclusion and exclusion criteria were collected for this study. Conclusions: this study revealed that there were gaps in the process of enteral diet supply by the Espírito Santo pharmacies, both concerning compliance with the protocol and patient follow-up by the professional who assists both the patient and the pharmacist who provides the input.

Resumen Antecedentes: Brasil incluyó la alimentación como un derecho social, haciendo que el Estado sea responsable ante los tribunales del suministro suficiente y adecuado de alimentos. Objetivos: evaluar el suministro de dietas enterales en las farmacias estatales de Espírito Santo. Métodos: para hacer esto utilizamos los formularios cumplimentados por los pacientes y representantes legales que contienen registros médicos con el fin de analizar los perfiles nutricionales y sociales de los usuarios durante dos años; además, se verificó el cumplimiento de los procesos administrativos con la ordenanza que instituyó el suministro de alimentos. Resultados: la muestra comprendió 204 pacientes que recibieron nutrición enteral, investigándose los procedimientos administrativos requeridos para suministrar a estos pacientes en siete (7/9) farmacias. Los datos mostraron que el grupo más común era el de mujeres (51 %), de raza blanca (51 %) y representadas legalmente (91 %), de 73,5 años de edad (11 a 109 años). Para este estudio se recopiló información sobre los datos antropométricos faltantes, el uso de términos y cálculos para obtener alimentos distintos a los recomendados, documentos incompletos, alteraciones en los exámenes físicos sugestivos de error y la no observancia de los criterios de inclusión y exclusión. Conclusiones: este estudio reveló que había vacíos en el proceso de suministro de dietas enterales por parte de las farmacias de Espírito Santo en lo que respecta tanto al cumplimiento del protocolo como al seguimiento del paciente por el profesional que lo atiende y el farmacéutico que proporciona la información.

https://doi.org/10.20960/nh.03257

11.

Inclusão educacional: estudo de caso de um aluno com dupla excepcionalidade
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Soares Coutinho-Souto, Waleska Karinne

; de Souza Fleith, Denise

Revista de Psicología (PUCP)

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jan 2021, Volume 39 N. 1 Pages 339 - 379

Resumen Las escuelas con orientación inclusiva son consideradas como un medio eficaz de combate a actitudes discriminatorias. En el caso de los alumnos superdotados, se ha observado un interés por la realización de estudios involucrando a aquellos que presentan, simultáneamente, las habilidades superiores y dificultades conductuales, emocionales y de aprendizaje, fenómeno denominado doble excepcionalidad. El objetivo de este estudio de caso fue analizar la inclusión educativa de un alumno superdotado con trastorno de Asperger desde la perspectiva de gestores, profesores, madre y del alumno. La inclusión del participante fue considerada un proceso de naturaleza compleja y multidimensional por depender de la participación de toda la comunidad escolar y de la familia. Se verificó que la atención educativa especializada favoreció su inclusión educativa.

Abstract Schools with an inclusive perspective are considered an efficient tool to fight the discriminatory attitudes. In the case of gifted students, there has been an interest in carrying out studies involving those who present, simultaneously to the higher abilities, behavioral, emotional and learning difficulties, a phenomenon named dual exceptionality. The purpose of this case study was to analyze the educational inclusion of a gifted student with Asperger’s disorder from the perspective of managers, teachers, mother and student himself. The educational inclusion of the participant was considered a complex and multidimensional process because it depends on the participation of the whole school community and family. It was verified that the specialized educational service favored the inclusion of the dual exceptional student.

Résumé Les écoles à orientation inclusive sont considérées comme un moyen efficace de lutter contre les attitudes discriminatoires. Dans le cas des étudiantes surdoués, on s’intéresse aux études qui concernent ceux qui présentent, simultanément aux compétences supérieures, des difficultés comportementales, émotionnelles et d’apprentissage, un phénomène appelé la double exception. Le but de cette étude de cas était d’analyser l’inclusion éducative d’un étudiant surdoué avec le syndrome de Asperger du point de vue des gestionnaires, des enseignants, de la mère et de l’étudiant. L’inclusion scolaire du participant était considérée comme un processus complexe et multidimensionnel, car elle dépend de la participation de la communauté scolaire et de la famille. Il a été vérifié que le service éducatif spécialisé favorisait son inclusion scolaire.

Resumo Escolas com orientação inclusiva são consideradas um meio eficaz de combate às atitudes discriminatórias. No caso dos alunos superdotados, tem-se observado um interesse pela realização de estudos envolvendo aqueles que apresentam, simultaneamente às habilidades superiores, dificuldades comportamentais, emocionais e de aprendizagem, fenômeno denominado dupla excepcionalidade. O objetivo deste estudo de caso foi analisar a inclusão educacional de um aluno superdotado com transtorno de Asperger a partir da perspectiva de gestores, professores, mãe e do próprio aluno. A inclusão educacional do aluno participante da pesquisa foi considerada um processo de natureza complexa e multidimensional por depender da participação de toda a comunidade escolar e da família. Verificou-se que o atendimento educacional especializado favoreceu sua inclusão educacional.

https://doi.org/10.18800/psico.202101.014

12.

Aerobic Exercise Increases the Damage to the Femoral Properties of Growing Rats with Protein-Based Malnutrition
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Miranda, Denise Coutinho de

; Lavorato, Victor Neiva

; Carneiro-Júnior, Miguel Araújo

; Paula, Ana Beatriz Rezende de

; Silva, Karina Ana

; Drummond, Filipe Rios

; Silva, Marcelo Eustáquio

; Cabral, Carlos Augusto Costa

; Isoldi, Mauro César

; Natali, Antônio José

Brazilian Archives of Biology and Technology

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2021, Volume 64 elocation e21210085

Abstract: En | Text: En | PDF: En

Abstract The present study investigated the effects of aerobic physical training on the femoral morphological, densitometric and biomechanical properties in growing male rats subjected to protein-based malnutrition. Four-week-old male Wistar rats were randomized into groups of 10 animals: Control Sedentary (CS), Control Trained (CT), Malnourished Sedentary (MS) and Malnourished Trained (MT). Control and malnourished animals received diets with 12% protein and 6% protein, respectively. The trained groups were submitted to a treadmill running program for 8 weeks. Total proteins and albumin were analyzed in the animals' blood plasma. Histological, densitometric and biomechanical analyzes were performed on the animals' femur. Body mass gain, physical performance, biochemical markers and the femoral morphological, densitometric and biomechanical properties were determined. Exercise tolerance increased in trained groups. Malnourished animals exhibited lower serum protein and albumin levels than controls. Porosity and trabecular bone density were not different between groups. The femoral maximum load, maximum load until fracture, resilience, stiffness, tenacity and densitometric properties were reduced by malnutrition. Physical training associated with malnutrition exacerbated the impairment in the femoral maximum load, maximum load until fracture, bone mineral content and density. Aerobic physical training worsens the damages induced by protein-based malnutrition in the femoral biomechanical and densitometric properties of growing male rats.

https://doi.org/10.1590/1678-4324-2021210085

13.

Anti-Ehrlichia properties of the dichloromethane fraction of Ageratum conyzoides associated with doxycycline: In vitro study
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Rosário, Carla Janaina Rebouças Marques do

; Rocha, Claudia Quintino da

; Aguiar, Daniel Moura de

; Lima, Cristian Alex Aquino

; Coutinho, Denise Fernandes

; Melo, Ferdinan Almeida

Ciência Rural

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2021, Volume 51 N. 10 elocation e20200999

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO: O crescente número de casos de erliquiose canina por Ehrlichia canis em hospitais e clínicas veterinárias tem demonstrado a necessidade de um novo protocolo de medicamentos para essa doença. A doxiciclina é usada para tratar a erliquiose, mas a resistência do microrganismo a esse protocolo de tratamento, bem como os diversos efeitos colaterais para os animais, tornou-se uma preocupação. Vários estudos têm demonstrado interação positiva com extratos de plantas e fármacos, que permitem a redução da concentração necessária para produzir o efeito desejado, minimizando os efeitos adversos. Este estudo determinou a eficiência da combinação da fração diclorometânica (DCM) de Ageratum conyzoides L. com atividade anti-Ehrlichia canis associada com doxiciclina por meio do ensaio de Checkerboard. O material vegetal foi coletado em São Luís, Maranhão, nordeste do Brasil, seguido pela extração em MeOH:H2O (8:2) e partição da fração diclorometânica. Após a determinação da Concentração Inibitória Mínima (CIM) da fração em estudo frente às células DH82 infectadas com Ehrlichia canis, a mesma foi combinada com a doxiciclina para derivação do Índice de Concentração Inibitória da Fração (Índice CIF). Observou-se uma redução de 5,83 vezes a concentração inibitória mínima da doxiciclina mostrando que esta fração de A. conyzoides, composta predominantemente por lignanas identificadas por espectrometria de massas, notavelmente intensificou a atividade desse fármaco contra E. canis, resultando em um efeito sinérgico.

ABSTRACT: The increasing number of cases of canine ehrlichiosis caused by Ehrlichia canis in hospitals and veterinary clinics has demonstrated the need for a new drug protocol for this disease. Doxycycline is used to treat ehrlichiosis, but the resistance of the microorganism to this treatment protocol, as well as the various side effects to the animals, has become a concern. Several studies have shown a positive interaction with extracts of plants and drugs, which allow for the reduction of the concentration necessary to produce the desired effect, minimizing adverse effects. This study determined the efficiency of the combination of the dichloromethane (DCM) fraction of Ageratum conyzoides L. with anti-Ehrlichia activity and doxycycline by using the checkerboard assay. Plant material was collected in São Luís, northeastern Brazil, followed by extraction in MeOH: H2O (8:2) and partitioning of the DCM fraction. After determining the Minimum Inhibitory Concentration (MIC) of the fraction under study against DH82 cells infected with Ehrlichia canis, it was combined with doxycycline to derive the Fractional Inhibitory Concentration Index (CIF Index). A reduction of 5.83 times the doxycycline minimum inhibitory concentration was observed, showing that this fraction of A. conyzoides composed predominantly by the class of lignans, identified by mass spectrometry notably intensified the activity of doxycycline against E. canis, resulting in a synergistic effect.

https://doi.org/10.1590/0103-8478cr20200999 134 downloads

14.

Medo, perplexidade, negacionismo, aturdimento - e luto: afetos do sujeito da pandemia
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Jorge, Marco Antonio Coutinho

; Mello, Denise Maurano

; Nunes, Macla Ribeiro

Revista Latinoamericana de Psicopatologia Fundamental

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sep 2020, Volume 23 N. 3 Pages 583 - 596

Este artigo pretende refletir sobre as falas dos sujeitos em tratamento psicanalítico durante a pandemia de COVID-19 pelo novo coronavírus (SARS-CoV-2) e, para tanto, elegeu alguns significantes que se impuseram à escuta dos psicanalistas ao longo do tempo.

This article aims to reflect on the discourses of subjects who are undergoing psychoanalytic treatment during the COVID-19 pandemic caused by the new coronavirus (SARS-CoV-2). To achieve that goal, we selected some signifiers which imposed themselves to the therapists’ listening over time.

Este artículo pretende reflexionar sobre el discurso de los sujetos en tratamiento psicoanalítico durante la pandemia de COVID-19, ocasionado por el nuevo coronavirus (SARS-CoV-2) y, para ello, se eligieron algunos significantes que se impusieron a lo largo del tiempo a la escucha de los terapeutas.

Cet article entend réfléchir sur les discours des sujets sous traitement psychanalytique lors de la pandémie de COVID-19 par le nouveau coronavirus (SARS-CoV-2) et, à cet effet, a élu certains signifiants qui se sont imposés à l’écoute des thérapeutes au fil du temps.

https://doi.org/10.1590/1415-4714.2020v23n3p583.9 4498 downloads

15.

Nephroprotective activity of the enriched polyphenol extract of Euterpe edulis Martius
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Cardoso, Priscylla Maria Martins

; Mazuco, Renata Alves

; Macedo, Lucas Soares Dazzi

; Polese, Ariele Abreu Venturini

; Barroso, Maria Eduarda de Souza

; Baratella, Waléria Gramilich

; Andrade, Tadeu Uggere de

; Lenz, Dominik

; Pereira, Thiago de Melo Costa

; Endringer, Denise Coutinho

Brazilian Journal of Pharmaceutical Sciences

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2020, Volume 56 elocation e18051

Abstract: En | Text: En | PDF: En

Contrast-induced nephropathy (NIC) is directly related to increased morbidity and mortality, and its treatment and prevention might be achieved by the administration of antioxidant products. The juçara palmetto (Euterpe edulis Martius) has fruits rich in phenolic compounds, which are known for their antioxidant activity. This work aimed to evaluate the nephroprotective activity of E. edulis pulp in the NIC animal model. The collected fruits were pulped, their contents of polyphenols and anthocyanins were quantified, and their antioxidant activity were evaluated. The nephroprotective effects were determined based on iodine contrast induction and evaluated by biochemical and histological analyses. The results showed that E. edulis pulp was rich in polyphenols (811 ± 16.7 mg EAG/g) and anthocyanins (181.25 mg/100 g) and had very strong antioxidant activity, as demonstrated by the DPPH (2,2-diphenyl-1-picryl-hydrazyl) method, which revealed an antioxidant activity index (AAI) of 3.4, and the 2,29-azinobis (3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) method, which revealed an IC50 of 0.59 ± 0.03 mg/mL. In the in vivo experiments, E. edulis pulp tended to provide renal protection and reduce renal dysfunction and tubular morphological lesions in mice after the induction of NIC, and these effects were obtained through the antioxidant activities of the polyphenols in the pulp.

https://doi.org/10.1590/s2175-97902019000318051 1062 downloads

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