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Gender and remote work: associations between mental health and hours of remote work and housework
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Silva-Costa, Aline

; Rotenberg, Lúcia

; Aquino, Estela M. L.

; Cardoso, Letícia de Oliveira

; Patrão, Ana Luísa

; Fonseca, Maria de Jesus M. da

; Griep, Rosane Härter

Ciência & Saúde Coletiva

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jan 2025, Volume 30 N. 1 elocation e04892023

Abstract: Pt En Es | Text: Pt En Es | PDF: Pt | PDF: En | PDF: Es

Resumo Investigar associações das horas de trabalho remoto (TR) e doméstico (TD), separadamente e combinadas (TT), com o gênero e o sofrimento mental de trabalhadores em trabalho remoto durante a pandemia de COVID-19. Estudo transversal com dados do ELSA-Brasil (N = 2.318). Em média, mulheres referiram mais tempo de TD e TT do que os homens, mas não foi observada diferença de gênero quanto ao TR. Depressão, ansiedade e estresse foram mais frequentes nas mulheres. Mulheres com jornadas mais longas (TR, TD e TT) apresentaram maiores chances de sintomas de ansiedade e estresse do que os homens com jornadas mais curtas. Para os sintomas de depressão, as razões de chance mais altas foram observadas apenas entre as mulheres com moderada ou longa jornadas de TD e TT. A perspectiva de gênero quanto ao efeito do trabalho remoto contribui para o reconhecimento de iniquidades em saúde entre homens e mulheres.

Abstract To investigate the association between hours of remote work (RWHs) and housework (HWHs), independently, as well as the combined total of work hours (WHs), with gender and mental health of remote workers during the COVID-19 pandemic. Cross-sectional study with data from the ELSA-Brasil (N = 2,318). On average, women reported more time spent on HWHs and WHs than men, while no difference was found in RWHs. Depression, anxiety and stress were more prevalent among women. Women with longer working hours (RWHs, HWHs and WHs) had higher odds of displaying anxiety or stress symptoms than men with shorter working hours. For symptoms of depression, the highest odds ratios were found only among those women with medium or long HWHs and long WHs. A gender perspective into studies of remote work effects has contributed to the recognition of health inequalities between men and women.

Resumen Investigar las asociaciones de las horas de trabajo remoto (TR) y horas de trabajo doméstico (TD), separadas y combinadas (TT), con el género y la salud mental de los trabajadores que trabajan de forma remota durante la pandemia de COVID-19. Estudio transversal con datos de lo ELSA-Brasil (N = 2.318). En promedio, las mujeres reportaron más tiempo de TD y TT que los hombres, pero no se observó diferencia entre géneros en términos de horas de TR. Depresión, ansiedad y estrés fueron más frecuentes en las mujeres. Las mujeres con jornadas laborales más largas (TR, TD y TT) tenían más probabilidades de experimentar síntomas de ansiedad y estrés que los hombres con jornadas laborales más cortas. Para los síntomas de depresión, los odds ratios más altos se observaron sólo entre mujeres con recorridos TD y TT moderados o largos. La perspectiva de género en los estudios sobre el efecto del trabajo remoto contribuye al reconocimiento de las inequidades en salud entre hombres y mujeres.

https://doi.org/10.1590/1413-81232025301.04892023

Neonatal mortality of live births with congenital diaphragmatic hernia in São Paulo State, Brazil: Failure of care?
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Marinonio, Ana Sílvia Scavacini

; Miyoshi, Milton Harumi

; Nobre, Daniela Testoni Costa

; Sanudo, Adriana

; Areco, Kelsy Catherina Nema

; Kawakami, Mandira Daripa

; Balda, Rita de Cássia Xavier

; Konstantyner, Tulio

; Oliveira, Carina Nunes Vieira e

; Bandiera-Paiva, Paulo

; Freitas, Rosa Maria Vieira de

; Teixeira, Monica La Porte

; Waldvogel, Bernadette Cunha

; Kiffer, Carlos Roberto Veiga

; Almeida, Maria Fernanda Branco de

; Guinsburg, Ruth

Revista Paulista de Pediatria

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2025, Volume 43 elocation e2024138

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Objetivo: Analisar se a organização do cuidado perinatal e a disponibilidade de leitos de unidades de terapia intensiva neonatal (UTIN) no Estado de São Paulo influenciaram a mortalidade de nascidos vivos com hérnia diafragmática congênita (HDC) entre 2004 e 2020. Analisar a distribuição espacial dos óbitos neonatais de nascidos vivos com HDC no Estado de São Paulo e sua associação com a disponibilidade de leitos de UTIN. Métodos: Estudo de base populacional que incluiu todos os nascidos vivos do estado de São Paulo, filhos de mães residentes no mesmo estado em 2004–2020. A definição de HDC foi baseada nos códigos da 10a Revisão da Classificação Internacional de Doenças da Organização Mundial da Saúde. Óbito neonatal associado à HDC foi definido como óbito até 27 dias após o nascimento de recém-nascidos com HDC. A distribuição da mortalidade neonatal associada à HDC (taxa por 10 mil nascidos vivos) e a disponibilidade de leitos de UTIN (≥1 ou não disponível) foi mapeada e sua associação avaliada por Mann-Whitney. Resultados: Entre 10.246.686 nascidos vivos, ocorreram 1.378 óbitos neonatais associados à HDC em 124/645 (19,2%) municípios do estado. A mediana da taxa de mortalidade neonatal associada à HDC nos municípios com leitos de UTIN foi de 1,22 (intervalo de confiança de 95% — IC95% 0,99–1,51), semelhante à encontrada nos municípios sem leitos de UTIN (1,40; IC95% 1,15–1,67; p=0,224). Conclusões: Os óbitos neonatais associados à HDC ocorreram de forma aleatória pelo estado de São Paulo, sem diferença nas taxas de mortalidade neonatal associadas à HDC entre os municípios com e sem leitos de UTIN disponíveis. Esses resultados sugerem a necessidade de implementação de estratégias de regionalização da assistência perinatal da HDC no estado.

ABSTRACT Objective: The aim of this study was to analyze if the healthcare organization of perinatal care and availability of referral neonatal intensive care units (NICU) impacted congenital diaphragmatic hernia (CDH) neonatal mortality in the period 2004–2020. This study analyzed the spatial distribution of neonatal deaths of live births with CDH in São Paulo State, Brazil, and its association with NICU beds’ availability. Methods: Population-based study of all live births in São Paulo State from mothers residing in the same State, from 2004 to 2020. CDH definition was based on WHO-ICD-10 codes; CDH-associated neonatal death was defined as death up to 27 days after birth of infants with CDH. The distribution of CDH-associated neonatal mortality (per 10,000 live births) and NICU beds’ availability (≥1 or not available) was mapped, and their association was evaluated by the Mann–Whitney test. Results: Among 10,246,686 live births, there were 1378 CDH-associated neonatal deaths across 124/645 (19.2%) municipalities of the State. The median CDH-associated neonatal mortality rate in municipalities with NICU beds was 1.22 (95%CI 0.99–1.51), similar to that found in municipalities with no NICU beds (1.40; 95%CI 1.15–1.67; p=0.224). Conclusions: CDH-associated neonatal deaths were spread throughout São Paulo State with no difference in CDH-associated neonatal mortality rates between municipalities with and without NICU beds available. These findings suggest the necessity of implementing regionalization strategies for CDH perinatal care in the State.

https://doi.org/10.1590/1984-0462/2025/43/2024138

Existe diferença nos resultados do vídeo teste do impulso cefálico em pacientes com diagnóstico nosológico de Doença de Ménière e Migrânea Vestibular?
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Aguiar, Maria Carolaine Ferreira

; Nascimento, Gizele Francisco Ferreira do

; Costa, Ana Paula Machado

; Ferreira, Lidiane Maria de Brito Macedo

; Diniz Júnior, José

; Mantello, Erika Barioni

CoDAS

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2025, Volume 37 N. 1 elocation e20230359

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

ABSTRACT Purpose To compare vestibulo-ocular reflex (VOR) gain values, gain symmetry between the semicircular canals (SCCs), and saccadic parameters in patients with a nosological diagnosis of Ménière’s disease (MD) and vestibular migraine (VM). Methods Observational, descriptive, cross-sectional, retrospective study, approved by the Research Ethics Committee, under evaluation report number 4.462.519. The study was based on medical record analysis of individuals who underwent the Video Head Impulse Test (vHIT). The sample included medical records of 33 patients, divided into two groups – G1, 18 patients with a nosological diagnosis of VM; G2, 15 patients with MD. The study collected information on age, sex, nosological diagnosis, symptoms, associated comorbidities, and vHIT results. Student's t-test and the linear regression model statistically analyzed the data. The significance level was set at 0.05 (95%). Results Females predominated (75.76%), with a mean age of 50.18 years. There was a predominance of normal VOR gain in the VM group (44.44%) and vestibular hypofunction in the MD group (40%). There was no significant difference between the groups’ mean gain per SCC, nor between the groups’ right and left SCCs. G1 had a higher percentage of evident saccades and saccadic dispersion. Conclusion Although there was no significant difference in VOR gain in the vHIT between the groups, there was a predominance of vestibular hypofunction in the MD group and normal results in the VM group.

RESUMO Objetivo Comparar os valores de ganho do reflexo vestíbulo-ocular (RVO), simetria de ganho entre os canais semicirculares (CSCs) e parâmetros sacádicos em pacientes com diagnóstico nosológico de doença de Méniere (DM) e migrânea vestibular (MV). Método Estudo observacional, descritivo, transversal e retrospectivo, aprovado pelo Comitê de Ética em Pesquisa, sob parecer: 4.462.519. O estudo foi realizado a partir da análise de prontuários de indivíduos que realizaram o vídeo teste do impulso cefálico (vHIT). Foram incluídos prontuários de 33 pacientes, divididos em dois grupos: G1, 18 pacientes com diagnóstico nosológico de MV, G2, 15 pacientes com diagnóstico de DM. Foram coletadas informações sobre idade, gênero, diagnóstico nosológico, sintomas, comorbidades associadas e resultados do vHIT. Os dados obtidos foram analisados estatisticamente, por meio do Teste t-student e Modelo de regressão linear. Foi adotado o nível de significância de 0,05 (95%). Resultados O sexo prevalente foi o feminino (75,76%), com idade média de 50,18 anos. Observou- se predomínio do ganho do RVO dentro dos padrões de normalidade para o grupo MV (44,44%) e da hipofunção vestibular para o grupo DM (40%). Não houve diferença significativa entre a média de ganho por CSC, dos grupos, nem entre os CSCs direito e esquerdo, dos grupos. Quanto aos parâmetros sacádicos, o G1 apresentou maior percentual de sacadas evidentes e da dispersão sacádica. Conclusão Embora não se tenha encontrado diferença significativa entre o ganho do RVO no vHIT entre os grupos, observou-se predomínio da hipofunção vestibular no grupo DM e de resultados dentro da normalidade no grupo MV.

https://doi.org/10.1590/2317-1782/e20230359pt

Safety of two-dose schedule of COVID-19 adsorbed inactivated vaccine (CoronaVac; Sinovac/Butantan) and heterologous additional doses of mRNA BNT162b2 (Pfizer/BioNTech) in immunocompromised and immunocompetent individuals
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Miyaji, Karina Takesaki

; Ibrahim, Karim Yaqub

; Infante, Vanessa

; Moreira, Raquel Megale

; Santos, Carolina Ferreira dos Belizário, Juliana de Cássia Pinto, Maria Isabel de Moraes Marinho, Ana Karolina Barreto Berselli Pereira, Juliana Marquezi Mello, Liliane Saraiva de Silva, Vitor Gabriel Lopes da Sato, Paula Keiko Strabelli, Tânia Mara Varejão Ragiotto, Lucas Pacheco, Pedro Henrique Theotonio de Mesquita Braga, Patricia Emilia Loch, Ana Paula Precioso, Alexander Roberto Sartori, Ana Marli Christovam França, João Ítalo Lima, Marcos Alves de Ando, Mauricio Cesar Sampaio Rodrigues, Camila Cristina Martini Song, Alice Tung Wan Lara, Amanda Nazareth Belizário, Ana Cristina Lima, Anna Helena Simões Bortulucci de Zanetti, Ariane Cristina Barboza Paulo, Audrey Rose da Silveira Amancio de Rosa, Barbara Miranda dos Santos Moraes, Bruna Del Guerra de Carvalho Oliveira, Bruna Ribeiro de Picone, Camila de Melo Aranda, Carolina Sanches Troli, Carolinne Paioli Kokron, Cristina M. Terrabuio, Debora Raquel Benedita Abdala, Edson David Neto, Elias Nakanishi, Érika Yoshie Shimoda Lima, Fabiana Mascarenhas Souza Firmino, Fabio Batista Santos, Fernanda Barone Alves dos Bacal, Fernando Fatobene, Giancarlo Santana, Jaqueline Oliveira Kalil, Jorge Barbosa, Julia Gonçalves, Leandro Peres Otuyama, Leonardo Jun Pierrotti, Ligia Camera Compte, Livia Caroline Mariano Marinho, Livia Chaer, Livia Netto Seguro, Luis Fernando Azevedo, Luiz Sergio Ueda, Márcia Aiko Terreri, Maria Teresa Barros, Myrthes Anna Maragna Toledo Grecco, Octávio Sejas, Odeli Nicole Encinas Musqueira, Priscila Tavares Ito, Raquel Keiko de Luca Teixeira, Samia Silveira Souza Fidalgo, Serafim Costa, Silvia Figueiredo Campos, Silvia Vidal Fernandes, Tamiris Hinsching Rocha, Vanderson Geraldo Coelho, Vivian Caso

Revista do Instituto de Medicina Tropical de São Paulo

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2025, Volume 67 elocation e2

Abstract: En | Text: En | PDF: En

ABSTRACT Immunocompromised individuals were considered high-risk for severe disease due to SARS COV-2 infection. This study aimed to describe the safety of two doses of COVID-19 adsorbed inactivated vaccine (CoronaVac; Sinovac/Butantan), followed by additional doses of mRNA BNT162b2 (Pfizer/BioNTech) in immunocompromised (IC) adults, compared to immunocompetent/healthy (H) individuals. This phase 4, multicenter, open label study included solid organ transplant and hematopoietic stem cell transplant recipients, cancer patients and people with inborn errors of immunity with defects in antibody production, rheumatic, end-stage chronic kidney or liver disease, who were enrolled in the IC group. Participants received two doses of CoronaVac and additional doses of mRNA BNT162b2. Adverse reactions (AR) data were collected within seven days after each vaccination. Serious adverse events and of special interest (AESI) were monitored throughout the study. We included 241 immunocompromised and 100 immunocompetent subjects. Arthralgia, fatigue, myalgia, and nausea were more frequent in the IC group after CoronaVac. Following the first additional dose of mRNA BNT162, pain, induration, and tenderness at injection site, fatigue and myalgia were more frequent in the H group. A heart transplant recipient had a graft rejection temporally associated with the second CoronaVac dose, but there was no literature evidence of causal association. Four cases of AESI were considered related to the vaccine: three erythema multiforme after CoronaVac, all in IC participants, and one paresthesia after mRNA, in a H participant. Our findings were comparable to other studies that evaluated the safety of COVID-19 vaccines in different immunocompromised populations. Both vaccines were safe for immunocompromised participants.

https://doi.org/10.1590/s1678-9946202567002

Reach and engagement on the history of nursing on social media in light of Pierre Lévy
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Maia, Natália Maria Freitas e Silva

; Araújo, Agostinho Antônio Cruz

; Santos, Ana Maria Ribeiro dos

; Schreck, Rafaela Siqueira Costa

; Peres, Maria Angélica de Almeida

; Santos, Fernanda Batista Oliveira

Revista Brasileira de Enfermagem

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2025, Volume 78 N. 1 elocation e20240228

Abstract: Pt En Es | Text: Pt En Es | PDF: Pt | PDF: En | PDF: Es

RESUMO Objetivo: Analisar o alcance e o engajamento sobre a história da enfermagem nas mídias sociais do Centro de Memória da Escola de Enfermagem, da Universidade Federal de Minas Gerais (CEMENF/UFMG), à luz de Pierre Lévy. Métodos: Estudo documental realizado no Instagram do CEMENF e no YouTube da Escola de Enfermagem da UFMG, de setembro a dezembro de 2021. Os achados foram analisados segundo os conceitos de Pierre Lévy. Resultados: As publicações nas redes sociais, nos anos de 2020 e 2021, resultaram em uma média de 6,79 postagens de feed e 1,42 Reels no Instagram, com média de 25,54 comentários nas postagens de feed e 512,17 visualizações nos Reels. Quanto ao Youtube, observa-se uma média de 1,58 postagens, com 2164,08 visualizações e 101,58 curtidas. Conclusões: O Ciberespaço pode ser um potente instrumento de aproximação de museus universitários com a sociedade e de difusão de projetos de extensão e de pesquisa.

ABSTRACT Objective: To analyze the reach and engagement on the history of nursing on social media of the Memory Center of the School of Nursing, Federal University of Minas Gerais (CEMENF/UFMG), in light of Pierre Lévy. Methods: Documentary study carried out on CEMENF’s Instagram and on the YouTube of the School of Nursing of UFMG, from September to December 2021. The findings were analyzed according to Pierre Lévy’s concepts. Results: Publications on social media, in the years 2020 and 2021, resulted in an average of 6.79 feed posts and 1.42 Reels on Instagram, with an average of 25.54 comments on feed posts and 512.17 views on Reels. As for YouTube, an average of 1.58 posts was observed, with 2164.08 views and 101.58 likes. Conclusions: Cyberspace can be a powerful instrument for bringing university museums closer to society and for disseminating extension and research projects.

RESUMEN Objetivo: Analizar el alcance y el compromiso con la historia de la enfermería en las redes sociales del Centro de Memoria de la Escuela de Enfermería de la Universidad Federal de Minas Gerais (CEMENF/UFMG) a la luz de Pierre Lévy. Métodos: Se trata de un estudio documental del CEMENF realizado por Instagram y YouTube de la Escuela de Enfermería de la UFMG, entre septiembre y diciembre de 2021. Las deducciones se analizaron según los conceptos de Pierre Lévy. Resultados: Las publicaciones en redes sociales en 2020 y 2021 dieron lugar a una media de 6,79 feed posts y 1,42 Reels en Instagram, con una media de 25,54 comentarios en los feed posts y 512,17 visualizaciones en los Reels. Con relación a YouTube, hubo una media de 1,58 publicaciones con 2164,08 visualizaciones y 101,58 me gusta. Conclusiones: El ciberespacio puede ser una poderosa herramienta para acercar los museos universitarios a la sociedad y difundir proyectos de extensión e investigación.

https://doi.org/10.1590/0034-7167-2024-0228

Reach and engagement on the history of nursing on social media in light of Pierre Lévy
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Maia, Natália Maria Freitas e Silva

; Araújo, Agostinho Antônio Cruz

; Santos, Ana Maria Ribeiro dos

; Schreck, Rafaela Siqueira Costa

; Peres, Maria Angélica de Almeida

; Santos, Fernanda Batista Oliveira

Revista Brasileira de Enfermagem

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2025, Volume 78 N. 1 elocation e20240228

Abstract: Pt En Es | Text: Pt En Es | PDF: Pt | PDF: En | PDF: Es

https://doi.org/10.1590/0034-7167-2024-0228

New discoveries of the action of L-ascorbic acid (vitamin C) - Enhanced efficacy in formulations
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Oliveira, Andressa Costa de

; Morocho-Jacome, Ana Lucia Martins, Tércio Elyan Azevedo Pinto, Claudinéia Aparecida Sales de Oliveira Baby, André Rolim Velasco, Maria Valéria Robles

Brazilian Journal of Pharmaceutical Sciences

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2025, Volume 61 elocation e24274

Abstract: En | Text: En | PDF: En

Abstract Skin oxidation can impair physiological functions and induce skin diseases, such as photoaging and cancer. L-ascorbic acid (L-AA), or vitamin C, is commonly used in cosmetics because it is a potent antioxidant, inhibits melanogenesis, and promotes collagen and elastin synthesis in the skin. This study developed strategies to improve the stability of L-AA in its pure form with or without caffeic acid (CA) and evaluated its clinical efficacy using an ex vivo method. Oil/water emulsions were prepared with antioxidants and normal stability tests were conducted (various temperatures for 360 days). Antioxidant activity was assessed using a DPPH assay, and L-AA content was quantified by high-performance liquid chromatography. The thiobarbituric acid reactive substances method characterized the inhibition of lipid peroxides in the stratum corneum ex vivo. The formulation F1 (base + 10.0% L-AA) exhibited better L-AA stability over 360 days. The formulations F1 and F2 (base + 10.0% L-AA + 0.2% CA) increased the production of lipid peroxides when applied to the stratum corneum ex vivo and irradiated; however, when not irradiated, they inhibited the production of reactive oxygen species. For greater clinical efficacy of vitamin C on the skin, nighttime use is suggested as well as storage at low temperatures.

https://doi.org/10.1590/s2175-97902025e24274

Joint statement on evidence-based practices in mechanical ventilation: suggestions from two Brazilian medical societies
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Ferreira, Juliana Carvalho

; Vianna, Arthur Oswaldo de Abreu

; Pinheiro, Bruno Valle

; Maia, Israel Silva

; Baldisserotto, Sérgio Vasconcellos

; Isola, Alexandre Marini

; Cavalcanti, Alexandre Biasi Gama, Ana Maria Casati Nogueira da Rocha, Angelo Roncalli Miranda Oliveira, Antonio Gonçalves de Serpa Neto, Ary Farias, Augusto Manoel de Carvalho Orlando, Bianca Rodrigues Esteves, Bruno da Costa Mazza, Bruno Franco Silveira, Camila de Freitas Martins Soares Carvalho, Carlos Roberto Ribeiro de Toufen Junior, Carlos Barbas, Carmen Silvia Valente Teixeira, Cassiano Silveira, Débora Dutra da Medeiros, Denise Machado Parolo, Edino Costa, Eduardo Leite Vieira Caser, Eliana Bernadete Oliveira, Ellen Pierre de Banholzer, Eric Grieger Carvalho, Erich Vidal Amorim, Fabio Ferreira Saddy, Felipe Gonçalves, Fernanda Alves Ferreira Galas, Filomena Regina Barbosa Gomes Zanatta, Giovanna Carolina Gardini Silva, Gisele Sampaio Westphal, Glauco Adrieno Matos, Gustavo Faissol Janot de Souza, João Claudio Emmerich de Silva Junior, João Manoel Valiatti, Jorge Luis dos Santos Nascimento Junior, José Ribamar do Rocco, Jose Rodolfo Hajjar, Ludhmila Abrahão Forgiarini Junior, Luiz Alberto Malbuisson, Luiz Marcelo Sá Holanda, Marcelo Alcantara Amato, Marcelo Britto Passos Park, Marcelo Oliveira, Marco Antonio da Rosa e Reis, Marco Antonio Soares Tavares, Marcos Soares Souza, Mario Henrique Dutra de Damasceno, Marta Cristina Pauleti Lira-Batista, Marta Maria da Silva Pattacini, Max Morais Assunção, Murillo Santucci Cesar de Oliveira, Neymar Elias de Franzosi, Oellen Stuani Rocco, Patricia Rieken Macedo Caruso, Pedro Silva, Pedro Leme Mendes, Pedro Vitale Duarte, Pericles Almeida Delfino Santa Neto, Renato Fabio Alberto Della Rodrigues, Ricardo Goulart Cordioli, Ricardo Luiz Palazzo, Roberta Fittipaldi Goldwasser, Rosane Pinheiro, Sabrina dos Santos Justino, Sandra Regina Nemer, Sergio Nogueira Oliveira, Vanessa Martins de Silva, Vinicius Zacarias Maldaner da Nedel, Wagner Luis Bellissimo-Rodrigues, Wanessa Teixeira Oliveira Filho, Wilson de

Critical Care Science

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2025, Volume 37 elocation e20250242en

Abstract: En | Text: En | PDF: En

ABSTRACT Mechanical ventilation can be a life-saving intervention, but its implementation requires a multidisciplinary approach, with an understanding of its indications and contraindications due to the potential for complications. The management of mechanical ventilation should be part of the curricula during clinical training; however, trainees and practicing professionals frequently report low confidence in managing mechanical ventilation, often seeking additional sources of knowledge. Review articles, consensus statements and clinical practice guidelines have become important sources of guidance in mechanical ventilation, and although clinical practice guidelines offer rigorously developed recommendations, they take a long time to develop and can address only a limited number of clinical questions. The Associação de Medicina Intensiva Brasileira and the Sociedade Brasileira de Pneumologia e Tisiologia sponsored the development of a joint statement addressing all aspects of mechanical ventilation, which was divided into 38 topics. Seventy-five experts from all regions of Brazil worked in pairs to perform scoping reviews, searching for publications on their specific topic of mechanical ventilation in the last 20 years in the highest impact factor journals in the areas of intensive care, pulmonology, and anesthesiology. Each pair produced suggestions and considerations on their topics, which were presented to the entire group in a plenary session for modification when necessary and approval. The result was a comprehensive document encompassing all aspects of mechanical ventilation to provide guidance at the bedside. In this article, we report the methodology used to produce the document and highlight the most important suggestions and considerations of the document, which has been made available to the public in Portuguese.

https://doi.org/10.62675/2965-2774.20250242-en

O efeito das redistribuições dos códigos garbage na evolução da mortalidade por Doenças Crônicas no Brasil, 2010 a 2019
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Malta, Deborah Carvalho

; Teixeira, Renato Azeredo

; Souza, Juliana Bottoni de

; Aquino, Érika Carvalho de

; Dantas Júnior, Ademar B.

; Soares Filho, Adauto M.

; França, Elisabeth Barboza

; Vasconcelos, Ana Maria N.

; Souza, Fátima Marinho de

; Ishitani, Lenice Harumi

; Gomes, Crizian Saar

; Montenegro, Marli M. Silva

; Araújo, Valdelaine E. M. de

; Faria, Shirlei M. Costa

; Duncan, Bruce Bartholow

; Ribeiro, Antônio Luiz Pinho

Ciência & Saúde Coletiva

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2025, Volume 30 N. 3 elocation e00492024

Abstract: Pt Es En | Text: Pt Es En | PDF: Pt | PDF: Es | PDF: En

Resumo O estudo objetivou estimar a mortalidade prematura (30 a 69 anos) por quatro grupos prioritários de DCNT no Brasil, no período de 2010 a 2019, comparando dados do Sistema de Informações sobre Mortalidade (SIM) brutos, sem correção, dados do SIM corrigidos pela redistribuição dos CG e sub-registro e dados extraídos do estudo Carga Global de Doenças (GBD). As taxas de mortalidade prematura por DCNT mostraram redução no período analisado. Embora os métodos de correção tenham modificado pouco as tendências temporais, foi observado as taxas de mortalidade calculadas com os dados corrigidos foram expressivamente maiores que as sem correção. Essa variação foi heterogênea entre as Unidades Federadas. As taxas estimadas pelo método do SIM bruto variaram de 322,0 a 276,1 óbitos por 100 mil habitantes, enquanto as taxas do SIM redistribuído foram de 340,4 a 296,8 óbitos por 100 mil habitantes. As taxas estimadas para o GDB variaram de 371,6 a 323,0 óbitos por 100 mil habitantes. Em conclusão o presente estudo destaca a importância de se adotar métodos que possam ser aplicados para que tenhamos estatísticas relacionadas à mortalidade mais fidedignas, o que contribui para a melhoria contínua da definição das causas de morte no SIM.

Resumen Este estudio tuvo como objetivo estimar la mortalidad prematura (30-69 años) para cuatro grupos prioritarios de ENT en Brasil de 2010 a 2019, comparando datos brutos y no ajustados del Sistema de Información de Mortalidad (SIM), datos del SIM ajustados por redistribución del CB y subregistro, y datos extraídos del estudio de la Carga Global de Enfermedad (CGE). Las tasas de mortalidad prematura por ENT disminuyeron en el período analizado. Aunque los métodos de ajuste apenas modificaron las tendencias temporales, observamos que las tasas de mortalidad calculadas con datos ajustados fueron significativamente más altas que las sin ajuste. Esta variación fue heterogénea entre las Unidades Federadas. Las tasas estimadas por el método SIM bruto variaron de 322,0 a 276,1 defunciones por 100 mil habitantes, mientras que las tasas SIM redistribuidas variaron de 340,4 a 296,8 defunciones por 100 mil habitantes. Las tasas estimadas para la CGE variaron de 371,6 a 323,0 defunciones por 100 mil habitantes. En conclusión, este estudio resalta la importancia de adoptar métodos que puedan aplicarse para lograr estadísticas de mortalidad más confiables, que mejoren continuamente la definición de las causas de defunción en el SIM.

Abstract This study aimed to estimate premature mortality (30-69 years) for four priority NCD groups in Brazil from 2010 to 2019, comparing crude data from the Mortality Information System (SIM), SIM data adjusted by GC redistribution and underreporting, and data extracted from the Global Burden of Disease (GBD) study. Premature mortality rates due to NCDs declined in the period analyzed. Although the adjustment methods hardly changed temporal trends, we observed that mortality rates calculated with adjusted data were significantly higher than those without adjustment. This variation was heterogeneous among the Federated Units. The rates estimated by the crude SIM method ranged from 322.0 to 276.1 deaths per 100 thousand inhabitants, while the redistributed SIM rates ranged from 340.4 to 296.8 deaths per 100 thousand inhabitants. The estimated rates for the GBD ranged from 371.6 to 323.0 deaths per 100 thousand inhabitants. In conclusion, this study highlights the importance of adopting methods that can be applied to achieve more reliable mortality statistics, which continuously improves the definition of death causes in the SIM.

https://doi.org/10.1590/1413-81232025303.00492024

10.

Gender and remote work: associations between mental health and hours of remote work and housework
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Silva-Costa, Aline

; Rotenberg, Lúcia

; Aquino, Estela M. L.

; Cardoso, Letícia de Oliveira

; Patrão, Ana Luísa

; Fonseca, Maria de Jesus M. da

; Griep, Rosane Härter

Ciência & Saúde Coletiva

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2025, Volume 30 N. 1 elocation e04892023

Abstract: Pt Es En | Text: Pt Es En | PDF: Pt | PDF: Es | PDF: En

https://doi.org/10.1590/1413-81232025301.04892023

11.

Food insecurity and water insecurity measurement in Brazil: Sustainable Development Goals monitoring through experiential scales
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Salles-Costa, Rosana

; Cherol, Camilla Christine de Souza

; Palmeira, Poliana de Araújo

; Segall-Corrêa, Ana Maria

; Young, Sera Lewise

; Pérez-Escamilla, Rafael

; Lignani, Juliana de Bem

; Vianna, Rodrigo Pinheiro de Toledo

; Mata, Mayline Menezes da

; Medeiros, Maria Angélica Tavares de

; Pasquim, Elaine Martins

; Barbosa, Juliana Chaves

; Lima, Thainá Ferreira de

; García-Obregón, Olga Patrícia

; Gaitán-Rossi, Pablo

; Lima, Juliana Schober Gonçalves

; Grossi, Mauro Eduardo Del

; Voci, Silvia Maria

; Santos, Sandra Maria Chaves dos

; Melgar-Quiñonez, Hugo Ramiro

Cadernos de Saúde Pública

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2025, Volume 41 N. 2 elocation e00153524

Abstract: En | Text: En | PDF: En

https://doi.org/10.1590/0102-311xen153524

12.

Chemical and dereplication studies of Palicourea tomentosa (Aubl.) Borhidi and their antimicrobial and anticholinesterase activities
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Cecatto, Ana J.

; Formagio, Anelise S. N. Buzanello-Martins, Cleide V. Fortuna, Caroline Cabral, Márcia R. P. Costa, Willian F. da Baldoqui, Débora C. Sarragiotto, Maria H.

Química Nova

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2025, Volume 48 N. 1 elocation e-20250007

Abstract: En | Text: En | PDF: En

Palicourea tomentosa (Aubl.) Borhidi (Rubiaceae, Palicoureeae), earlier classified as Psychotria poeppigiana Müll. Arg., is used in folk medicine for a variety of diseases. Biological studies on the plant describes their vasorelaxant, antiplasmodial, antitumoural and anticholinesterase activities. To expand the knowledge on the chemical and biological potential of this species, in this work, phytochemical and dereplication studies, as well as antimicrobial and anticholinesterase evaluation of Palicourea tomentosa were carried out. Phytochemical investigation deals with the isolation of lutein (1), a mixture of dehydrovomifoliol (2) and megastigma-4,7-dien-3-one (3), loliolide (4), 5,13-epoxy-9-hydroxy-megastigma-7-en,3-one (5), vomifoliol (6), asperuloside (7), 3-O-p-coumaroylquinic acid (8), and a mixture of the pyrrolizidinoindoline alkaloids hodgkinsine (9), chimonanthine (10) and psychotriasine (11). The ultra-high performance liquid chromatography coupled to high-resolution mass spectrometry (UHPLC HRMS/MS) based on molecular networking dereplication of dichloromethane fraction led to putative identification of other two megastigmanes, one terpene lactone and three carotenoids, besides seven triterpenes and four indole alkaloids. The dichloromethane, ethyl acetate and hydromethanol fractions of P. tomentosa were able to inhibit Candida albicans with minimum inhibitory concentrations (MICs) of 125, 250 and 125 µg mL-1, respectively. The methanol crude extract, dichloromethane and alkaloid fractions inhibited selectively the butyrilcholinesterase (BuChE) at percentages of 63.09, 60.39 and 56.22%, respectively.

https://doi.org/10.21577/0100-4042.20250007

13.

Cadernos-diários em oficinas de jogos: Um recurso para autopercepção
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Souza, Maria Thereza Costa Coelho de Pétty, Ana Lúcia

Revista Psicopedagogia

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dec 2024, Volume 41 N. 126 Pages 546 - 554

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo O objetivo do trabalho é apresentar dois Cadernos-diários, que reúnem atividades lúdicas e desafios com jogos, usados como recurso didático para acessar a autopercepção de participantes de oficinas de jogos, no contexto de um programa de intervenção para crianças com dificuldades escolares. Foram construídas três categorias (criança e desempenho; criança e progresso/sentimento; criança e o outro) a partir dos temas: assuntos escolares, mudanças/conquistas percebidas e evolução do jogar. Do ponto de vista quantitativo, foi realizada uma distribuição das respostas por tema e categoria separando-se entre afirmativas e negativas. Do ponto de vista qualitativo, foram analisados os conteúdos das respostas com base nos conceitos de tomada de consciência e funções executivas. Os resultados indicaram que a autopercepção, desencadeada pelo uso dos Cadernos-diários em intervenções com jogos, serve como ponto de partida e torna os erros observáveis, mesmo que não ocorram mudanças imediatas. Isto demonstra uma possível contribuição deste recurso para gerar melhoria na qualidade dos procedimentos e ampliação do foco nas tarefas, com benefícios para a aprendizagem e o desenvolvimento.

Summary The aim of this paper is to present two activity notebooks, with playful activities and game challenges, used as teaching resources to access the self-perception of participants in game workshops held in the context of an intervention program for children with school difficulties. Three categories were constructed (child and performance; child and progress/feeling; child and the other) from the themes: school subjects; perceived changes/achievements and evolution of playing. From a quantitative point of view, responses were distributed by theme and category, separating between affirmative and negative responses. From a qualitative point of view, the contents of the responses were analysed based on the concepts of awareness and executive functions. Results indicated that self-perception, triggered by the use of the activity notebooks in interventions with games, serves as a starting point and puts mistakes in evidence, even if immediate changes do not occur. This demonstrates a possible contribution of this resource to generate improvements in the quality of procedures and expansion of the focus on tasks, with benefits for learning and development.

https://doi.org/10.51207/2179-4057.20240053

14.

Prevalência de infeções urinárias em pessoas institucionalizadas em instituições particulares de solidariedade social
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Ribeiro, Ana Rosa Jesus

; Chaves, Cláudia Margarida Correia Balula

; Reis, Alcinda Maria Sarmento do Sacramento Costa

Revista de Enfermagem Referência

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dec 2024, Volume serVI N. 3 elocation e31712

Abstract: Pt Es En | Text: Pt Es En | PDF: Pt | PDF: Es | PDF: En

Resumo Enquadramento: Nas pessoas idosas institucionalizadas, a infeção urinária é a mais comum, envolvendo 12% a 30% desta população, com pelo menos um episódio por ano, onde diversos fatores de risco influenciam a sua ocorrência. Objetivo: Determinar a prevalência das infeções urinárias em pessoas institucionalizadas numa instituição particular de solidariedade social e identificar os fatores de risco. Metodologia: Estudo epidemiológico observacional transversal. Os participantes são pessoas institucionalizadas numa instituição particular de solidariedade social e que pertencem a três valências diferentes. Amostra por conveniência. A colheita de dados realizou-se durante 8 meses, com registo do número total de utentes das várias valências (n = 171). Resultados: A prevalência de infeção urinária na instituição foi de 18,1%. Ocorreram mais casos em mulheres (p = 0,641) e em pessoas com idade superior a 75 anos (p = 0,269), mas sem diferenças significativas. O local de internamento demonstrou ter influência no risco de desenvolvimento de infeção urinária (p = 0,024). Conclusão: Das 171 pessoas internadas, 31 desenvolveram infeção urinária. São necessárias atitudes educativas e preventivas.

Resumen Marco contextual: En los ancianos institucionalizados, las infecciones del tracto urinario son las más comunes, afectando del 12% al 30% de esta población, con al menos un episodio por año, donde varios factores de riesgo influyen en su aparición. Objetivo: Determinar la prevalencia de infecciones urinarias en personas institucionalizadas en una institución privada de solidaridad social e identificar los factores de riesgo. Metodología: Estudio epidemiológico observacional transversal. Los participantes fueron personas institucionalizadas en una institución privada de solidaridad social y pertenecientes a tres servicios diferentes. Muestra de conveniencia. Los datos se recogieron durante un período de 8 meses y se registró el número total de usuarios de los distintos centros (n = 171). Resultados: La prevalencia de infección urinaria en la institución fue del 18,1%. Hubo más casos en mujeres (p = 0,641) y en mayores de 75 años (p = 0,269), pero sin diferencias significativas. Se demostró que el lugar de hospitalización influía en el riesgo de desarrollar infección urinaria (p = 0,024). Conclusión: De las 171 personas hospitalizadas, 31 desarrollaron infección urinaria. Se necesitan actitudes educativas y preventivas.

Abstract Background: In institutionalized elderly people, urinary tract infections are the most common, involving 12% to 30% of this population, with at least one episode per year, where several risk factors influence their occurrence. Objective: To determine the prevalence of urinary tract infections in older people institutionalized in a private institution of social solidarity and to identify the risk factors. Methodology: This is a cross-sectional, observational, and epidemiological study conducted on a convenience sample of people who are institutionalized in a private institution of social solidarity and belong to three different services. Data was collected over 8 months, and the number of patients in the different services was recorded (n = 171). Results: The institution had a urinary tract infection prevalence of 18.1%. Although more cases occurred in women (p = 0.641) and people older than 75 years (p = 0.269), there were no significant differences. Location of hospitalization was identified as a risk factor for developing a urinary tract infection (p = 0.024). Conclusion: Out of the 171 people who were institutionalized, 31 developed a urinary tract infection. It is important to adopt educational and preventive measures.

https://doi.org/10.12707/rvi23.82.31712

15.

Hepatocellular Adenoma: A Life-Threatening Presentation of a Rare Liver Tumor - Case Report and Literature Review
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Lopes, Sara Ramos Santos, Inês Costa Teixeira, Madalena Sequeira, Cristiana Carvalho, Ana Maria Gamito, Élia

GE-Portuguese Journal of Gastroenterology

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dec 2024, Volume 31 N. 6 Pages 67 - 72

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

Abstract Hepatocellular adenoma is a rare benign liver tumor that occurs predominantly in young women who use exogenous estrogens. We describe a case of a 40-year-old woman on birth control pill who presented with acute right hypochondrial pain and signs of hemodynamical instability triggered by a large bleeding tumor in the right liver lobe. Arterial embolization was performed with cessation of bleeding. To determine etiology, magnetic resonance imaging was conducted with ﬁndings suggestive of a hepatocellular adenoma. The tumor was surgically resected, and histologic examination made the deﬁnite diagnosis of an inﬂammatory hepatocellular adenoma. This is a noteworthy case of a rare but potentially fatal complication of liver tumors, whose diagnosis requires a high index of suspicion. Clinicians should consider this diagnosis in young women on oral contraceptive pills who present with severe unexplained abdominal pain and hemodynamical instability. This case aimed to raise awareness of this condition, while reviewing important aspects concerning the management of hepatocellular adenomas.

Resumo O adenoma hepatocelular é um tumor hepático benigno, raro, que ocorre predominantemente em mulheres jovens sob contraceção oral. Apresentamos o caso de uma mulher de 40 anos, medicada com contracetivo oral, que se apresentou com dor súbita no hipocôndrio direito com instabilidade hemodinâmica, com origem num volumoso tumor no lobo direito do fígado com hemorragia ativa. A doente foi submetida a embolização arterial com cessação da hemorragia. Posteriormente, realizou uma ressonância magnética nuclear com achados sugestivos de um adenoma hepatocelular. O tumor foi ressecado cirurgicamente, tendo a histologia conﬁrmado o diagnóstico de adenoma hepatocelular de subtipo inﬂamatório. Este é um caso singular de uma complicação rara, mas potencialmente fatal dos tumores hepáticos benignos, cujo diagnóstico requer um elevado nível de suspeição. Deve ser considerado em mulheres jovens sob contracetivos orais que se apresentem com dor abdominal intensa e instabilidade hemodinâmica. O presente caso pretende alertar para esta entidade, revendo aspetos importantes na abordagem de adenomas hepatocelulares.

https://doi.org/10.1159/000538340

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