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au:Chaves, Luis Fernando

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Influence of shadowing in Sequoia sempervirens (D. Don) Endl. mini-stumps and mini-cuttings
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Navroski, Marcio Carlos

; Schicora, Liliane

; Pereira, Mariane de Oliveira

; Silva, Jaiton Jaime das Neves

; Duarte, Luís Fernando Chaves

; Schilisting, Thalia

Revista Ceres

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aug 2022, Volume 69 N. 4 Pages 443 - 448

Abstract: En | Text: En | PDF: En

ABSTRACT The aim of the work was to analyze the influence of variables such as shading, temperature and humidity in the production and rooting of mini-cuttings of Sequoia sempervirens (D. Dom) Endl. in a clonal mini-garden. The experiment was conducted at the Forest Nursery at the University of Santa Catarina State - CAV/UDESC, Lages - SC. The minicuttings were obtained by vegetative rescue of a single clone (A228). The original S. sempervirens individuals studied are located in the National Forest of São Francisco de Paula -RS (FLONA). Sprouts were collected 90 days after the application of girdling rescue techniques. Subsequently, mini-stumps were obtained, which were submitted to three different treatments: T1 - Mini-stumps without shading protection, T2 - Mini-stumps with single layer of shading and T3 - Mini-stumps with double layer of shading. There was no significant difference for humidity and temperature in relation to the production of mini-cuttings by the mini-stumps, while for shading the treatments T2 and T3 showed greater efficiency. It is possible that the shading treatments on S. sempervirens mini-stumps allows the vegetative tissue to be more juvenile, obtaining excellent results in cutting.

https://doi.org/10.1590/0034-737x202269040008

Identification of clusters of asthma control: A preliminary analysis of the Inspirers studies
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Jácome, Cristina

; Amaral, Rita

; Almeida, Rute

; Pereira, Ana Margarida

; Couto, Mariana

; Araújo, Luís

; Alves-Correia, Magna

; Pereira, Mariana

; Ferreira-Magalhães, Manuel

; Loureiro, Cláudia Chaves

; Catarata, Maria Joana

; Santos, Lília Maia

; Cabral, Sara

; Pereira, João

; Ramos, Bárbara

; Lopes, Cristina

; Mendes, Ana

; Lopes, Anabela

; Rodrigues, José Carlos Cidrais

; Oliveira, Georgeta

; Aguiar, Ana Paula

; Afonso, Ivete

; Carvalho, Joana

; Arrobas, Ana Maria

; Costa, José

; Valério, Margarida

; Pereira, Marta

; Almeida, Teresa

; Dias, Joana

; Bom, Ana Todo

; Azevedo, João

; Ribeiro, Carmelita

; Alves, Marta

; Pinto, Paula Leiria

; Neuparth, Nuno

; Neves, Ana Castro

; Palhinha, Ana

; Marques, João Gaspar

; Martins, Pedro

; Trincão, David Pina

; Todo-Bom, Filipa

; Santos, Maria Alvarenga

; Branco, Joana

; Costa, Alberto

; Neto, Armandina Silva

; Santalha, Marta

; Lozoya, Carlos

; Santos, Natacha

; Silva, Diana

; Vasconcelos, Maria João

; Barata, Luís Taborda

; Teixeira, Maria Fernanda

; Pinto, Diana

; Alves, Rodrigo Rodrigues

; Moreira, Ana Sofia

; Pinto, Cláudia Sofia

; Silva, Pedro Morais

; Alves, Carlos

; Câmara, Raquel

; Coelho, Didina

; Bordalo, Diana

; Carvalho, Fernanda

; Fernandes, Ricardo

; Ferreira, Rosário

; Oliveira, José Ferraz de

; Menezes, Fernando

; Gomes, Ricardo

; Calix, Maria José

; Marques, Ana

; Cardoso, João

; Emiliano, Madalena

; Gerardo, Rita

; Nunes, Carlos

; Ferreira, José Alberto

; Lopes, Inês

; Alves, Adelaide

; Fonseca, João Almeida

Revista Portuguesa de Imunoalergologia

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dec 2020, Volume 28 N. 4 Pages 231 - 240

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Objetivos: Identificar clusters de controlo da asma baseados no Teste de Controlo da Asma e Rinite Alérgica (CARAT) e comparar as características dos doentes nos diferentes clusters. Métodos: Adultos e adolescentes (≥13 anos) com asma persistente foram recrutados em 29 centros no contexto de 2 estudos observacionais do projeto INSPIRERS. Foram recolhidos dados relativos a características demográficas e clínicas, adesão ao inalador, crenças sobre a medicação, sintomas de ansiedade e depressão, qualidade de vida e controlo da asma (CARAT, >24 bom controlo). Foi efetuada uma análise hierárquica de clusters usando a pontuação total do CARAT (CARAT-T).Resultados: Foram analisados 410 doentes (68% adultos), com uma idade mediana (percentil 25-percentil 75) de 28 (16-46) anos. Foram identificados três clusters [média CARAT-T(min-max)]: cluster 1 [27(24-30)], cluster 2 [19(14-23)] e cluster 3 [10(2-13)]. Os doentes no cluster 1 (34%) apresentavam melhor controlo da asma, melhor qualidade de vida, maior adesão aos inaladores e usavam um único inalador. Os doentes nos clusters 2 (50%) e 3 (16%) tinham a asma não controlada, menor adesão aos inaladores, mais sintomas de ansiedade e depressão e mais de metade reportavam pelo menos uma exacerbação no último ano. Adicionalmente, os doentes no cluster 3 eram predominantemente mulheres, tinham mais consultas médicas não agendadas, apresentavam mais sintomas de ansiedade, percebiam uma maior necessidade dos inaladores, mas também uma maior preocupação associada ao seu uso. Não se verificaram diferenças na idade, índice de massa corporal, função pulmonar, hábitos tabágicos, hospitalizações ou tempo de seguimento pelo médico especialista. Conclusões: Um método não supervisionado baseado no CARAT-T, identificou 3 clusters de doentes com diferentes características clínicas. O cluster com melhor controlo apresenta um ponto de corte semelhante ao estabelecido no estudo de validação do CARAT. Este estudo sugere ainda a existência de um ponto de corte adicional para distinguir doença mais grave. Mais investigação é necessária para validar os clusters identificados

Aims: To identify distinct asthma control clusters based on Control of Allergic Rhinitis and Asthma Test (CARAT) and to compare patients’ characteristics among these clusters. Methods: Adults and adolescents (≥13 years) with persistent asthma were recruited at 29 Portuguese hospital outpatient clinics, in the context of two observational studies of the INSPIRERS project. Demographic and clinical characteristics, adherence to inhaled medication, beliefs about inhaled medication, anxiety and depression, quality of life, and asthma control (CARAT, >24 good control) were collected. Hierarchical cluster analysis was performed using CARAT total score (CARAT-T). Results: 410 patients (68% adults), with a median (percentile 25-percentile 75) age of 28 (16-46) years, were analysed. Three clusters were identified [mean CARAT-T (min-max)]: cluster 1 [27(24-30)], cluster 2 [19(14-23)] and cluster 3 [10(2-13)]. Patients in cluster 1 (34%) were characterised by better asthma control, better quality of life, higher inhaler adherence and use of a single inhaler. Patients in clusters 2 (50%) and 3 (16%) had uncontrolled asthma, lower inhaler adherence, more symptoms of anxiety and depression and more than half had at least one exacerbation in the previous year. Furthermore, patients in cluster 3 were predominantly female, had more unscheduled medical visits and more anxiety symptoms, perceived a higher necessity of their prescribed inhalers but also higher levels of concern about taking these inhalers. There were no differences in age, body mass index, lung function, smoking status, hospital admissions or specialist physician follow-up time among the three clusters. Conclusion: An unsupervised method based on CARAT-T, identified 3 clusters of patients with distinct, clinically meaningful characteristics. The cluster with better asthma control had a cut-off similar to the established in the validation study of CARAT and an additional cut-off seems to distinguish more severe disease. Further research is necessary to validate the asthma control clusters identified.

https://doi.org/10.32932/rpia.2020.12.046 633 downloads

Interfaces à transmissão e spillover do coronavírus entre florestas e cidades
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ACOSTA, ANDRE LUIS

; XAVIER, FERNANDO

; CHAVES, LEONARDO SUVEGES MOREIRA

; SABINO, ESTER CERDEIRA

; SARAIVA, ANTONIO MAURO

; SALLUM, MARIA ANICE MUREB

Estudos Avançados

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aug 2020, Volume 34 N. 99 Pages 191 - 208

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO O atual formato de desenvolvimento humano gera severos impactos ambientais, os quais repercutem negativamente na saúde; dentre eles, a intensificação da transmissão de doenças infecciosas, epidemias e pandemias, como a Covid-19. A forma como lidamos com a biodiversidade e os ecossistemas, em conjunto com as mudanças climáticas, viabiliza interfaces e corredores por onde ocorrem diversificação, spillover e circulação de vírus. Por esses meios, o Sars-CoV-2 poderá invadir biomas brasileiros, transformando florestas como a Amazônia em imensos reservatórios, de onde o coronavírus poderá retornar ainda mais agressivo à saúde.

ABSTRACT The current path of human development generates deleterious environmental impacts, which have negative impact on health; among them, intensified transmission of infectious diseases, epidemics and pandemics, such as covid-19. The way we usually deal with biodiversity and ecosystems, combined with the effects of climate change, make for interfaces and pathways that favor diversification, spillover and the circulation of viruses. By these means, Sars-CoV-2 may invade Brazilian biomes, transforming, for instance, the Amazon rain forest into a huge reservoir from where coronavirus may return even more aggressive to health.

https://doi.org/10.1590/s0103-4014.2020.3499.012 7697 downloads

Epidemiologia e desfecho dos pacientes de alto risco cirúrgico admitidos em unidades de terapia intensiva no Brasil
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Silva Júnior, João Manoel

; Chaves, Renato Carneiro de Freitas

; Corrêa, Thiago Domingos

; Assunção, Murillo Santucci Cesar de

; Katayama, Henrique Tadashi

; Bosso, Fabio Eduardo

; Amendola, Cristina Prata

; Serpa Neto, Ary

; Malbouisson, Luiz Marcelo Sá

; Oliveira, Neymar Elias de

; Veiga, Viviane Cordeiro

; Rojas, Salomón Soriano Ordinola

; Postalli, Natalia Fioravante

; Alvarisa, Thais Kawagoe

; Lucena, Bruno Melo Nobrega de

; Oliveira, Raphael Augusto Gomes de

; Sanches, Luciana Coelho

; Silva, Ulysses Vasconcellos de Andrade e

; Nassar Junior, Antonio Paulo

; Réa-Neto, Álvaro

; Amaral, Alexandre

; Teles, José Mário

; Freitas, Flávio Geraldo Rezende de

; Bafi, Antônio Tonete

; Pacheco, Eduardo Souza

; Ramos, Fernando José

; Vieira Júnior, José Mauro

; Pereira, Maria Augusta Santos Rahe

; Schwerz, Fábio Sartori

; Menezes, Giovanna Padoa de

; Magalhães, Danielle Dourado

; Castro, Cristine Pilati Pileggi

; Henrich, Sabrina Frighetto

; Toledo, Diogo Oliveira

; Parra, Bruna Fernanda Camargo Silva

; Dias, Fernando Suparregui

; Zerman, Luiza

; Formolo, Fernanda

; Nobrega, Marciano de Sousa

; Piras, Claudio

; Piras, Stéphanie de Barros

; Conti, Rodrigo

; Bittencourt, Paulo Lisboa

; D’Oliveira, Ricardo Azevedo Cruz

; Estrela, André Ricardo de Oliveira

; Oliveira, Mirella Cristine de

; Reese, Fernanda Baeumle

; Motta Júnior, Jarbas da Silva

; Câmara, Bruna Martins Dzivielevski da

; David-João, Paula Geraldes

; Tannous, Luana Alves

; Chaiben, Viviane Bernardes de Oliveira

; Miranda, Lorena Macedo Araújo

; Brasil, José Arthur dos Santos

; Deucher, Rafael Alexandre de Oliveira

; Ferreira, Marcos Henrique Borges

; Vilela, Denner Luiz

; Almeida, Guilherme Cincinato de

; Nedel, Wagner Luis

; Passos, Matheus Golenia dos

; Marin, Luiz Gustavo

; Oliveira Filho, Wilson de

; Coutinho, Raoni Machado

; Oliveira, Michele Cristina Lima de

; Friedman, Gilberto

; Meregalli, André

; Höher, Jorge Amilton

; Soares, Afonso José Celente

; Lobo, Suzana Margareth Ajeje

Revista Brasileira de Terapia Intensiva

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mar 2020, Volume 32 N. 1 Pages 17 - 27

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Objetivo: Definir o perfil epidemiológico e os principais determinantes de morbimortalidade dos pacientes cirúrgicos não cardíacos de alto risco no Brasil. Métodos: Estudo prospectivo, observacional e multicêntrico. Todos os pacientes cirúrgicos não cardíacos admitidos nas unidades de terapia intensiva, ou seja, considerados de alto risco, no período de 1 mês, foram avaliados e acompanhados diariamente por, no máximo, 7 dias na unidade de terapia intensiva, para determinação de complicações. As taxas de mortalidade em 28 dias de pós-operatório, na unidade de terapia intensiva e hospitalar foram avaliadas. Resultados: Participaram 29 unidades de terapia intensiva onde foram realizadas cirurgias em 25.500 pacientes, dos quais 904 (3,5%) de alto risco (intervalo de confiança de 95% - IC95% 3,3% - 3,8%), tendo sido incluídos no estudo. Dos pacientes envolvidos, 48,3% eram de unidades de terapia intensiva privadas e 51,7% de públicas. O tempo de internação na unidade de terapia intensiva foi de 2,0 (1,0 - 4,0) dias e hospitalar de 9,5 (5,4 - 18,6) dias. As taxas de complicações foram 29,9% (IC95% 26,4 - 33,7) e mortalidade em 28 dias pós-cirurgia 9,6% (IC95% 7,4 - 12,1). Os fatores independentes de risco para complicações foram Simplified Acute Physiology Score 3 (SAPS 3; razão de chance − RC = 1,02; IC95% 1,01 - 1,03) e Sequential Organ Failure Assessment Score (SOFA) da admissão na unidade de terapia intensiva (RC =1,17; IC95% 1,09 - 1,25), tempo de cirurgia (RC = 1,001; IC95% 1,000 - 1,002) e cirurgias de emergências (RC = 1,93; IC95% 1,10 - 3,38). Em adição, foram associados com mortalidade em 28 dias idade (RC = 1,032; IC95% 1,011 - 1,052) SAPS 3 (RC = 1,041; IC95% 1,107 - 1,279), SOFA (RC = 1,175; IC95% 1,069 - 1,292) e cirurgias emergenciais (RC = 2,509; IC95% 1,040 - 6,051). Conclusão: Pacientes com escores prognósticos mais elevados, idosos, tempo cirúrgico e cirurgias emergenciais estiveram fortemente associados a maior mortalidade em 28 dias e mais complicações durante permanência em unidade de terapia intensiva.

ABSTRACT Objective: To define the epidemiological profile and the main determinants of morbidity and mortality in noncardiac high surgical risk patients in Brazil. Methods: This was a prospective, observational and multicenter study. All noncardiac surgical patients admitted to intensive care units, i.e., those considered high risk, within a 1-month period were evaluated and monitored daily for a maximum of 7 days in the intensive care unit to determine complications. The 28-day postoperative, intensive care unit and hospital mortality rates were evaluated. Results: Twenty-nine intensive care units participated in the study. Surgeries were performed in 25,500 patients, of whom 904 (3.5%) were high-risk (95% confidence interval - 95%CI 3.3% - 3.8%) and were included in the study. Of the participating patients, 48.3% were from private intensive care units, and 51.7% were from public intensive care units. The length of stay in the intensive care unit was 2.0 (1.0 - 4.0) days, and the length of hospital stay was 9.5 (5.4 - 18.6) days. The complication rate was 29.9% (95%CI 26.4 - 33.7), and the 28-day postoperative mortality rate was 9.6% (95%CI 7.4 - 12.1). The independent risk factors for complications were the Simplified Acute Physiology Score 3 (SAPS 3; odds ratio - OR = 1.02; 95%CI 1.01 - 1.03) and Sequential Organ Failure Assessment Score (SOFA) on admission to the intensive care unit (OR = 1.17; 95%CI 1.09 - 1.25), surgical time (OR = 1.001, 95%CI 1.000 - 1.002) and emergency surgeries (OR = 1.93, 95%CI, 1.10 - 3.38). In addition, there were associations with 28-day mortality (OR = 1.032; 95%CI 1.011 - 1.052), SAPS 3 (OR = 1.041; 95%CI 1.107 - 1.279), SOFA (OR = 1.175, 95%CI 1.069 - 1.292) and emergency surgeries (OR = 2.509; 95%CI 1.040 - 6.051). Conclusion: Higher prognostic scores, elderly patients, longer surgical times and emergency surgeries were strongly associated with higher 28-day mortality and more complications during the intensive care unit stay.

https://doi.org/10.5935/0103-507x.20200005 1048 downloads

How pathological criteria can impact prognosis of tongue and floor of the mouth squamous cell carcinoma
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Rodrigues, Renata Miranda

; Bernardo, Vagner Gonçalves

; Da Silva, Sabrina Daniela

; Camisasca, Danielle Resende

; Faria, Paulo Antônio de Silvestre

; Dias, Fernando Luiz

; Pinto, Luís Felipe Ribeiro

; Albano, Rodolpho Mattos

; Bergmann, Anke

; Lourenço, Simone de Queiroz Chaves

Journal of Applied Oral Science

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2020, Volume 28 elocation e20190198

Abstract: En | Text: En | PDF: En

Abstract Pathological parameters have been indicated as tumor prognostic factors in oral carcinoma. Objective: The objective of this study was to investigate the impact of pathological parameters on prognosis of patients affected only by tongue and/or floor of the mouth squamous cell carcinoma (SCC). Methodology: In total, 380 patients treated in the Brazilian National Cancer Institute (INCA) from 1999 to 2006 were included. These patients underwent radical resection followed by neck dissection. The clinical and pathological characteristics were recorded. The Kaplan-Meier method and Cox proportional hazards model were used in survival analysis. Overall survival (OS), cancer-specific survival (CSS) and disease-free interval (DFI) were estimated. Cox residuals were evaluated using the R software version 3.5.2. Worst OS, CSS and DFI were observed in patients with tumors in advanced pathological stages (p<0.001), with the presence of perineural invasion (p<0.001) and vascular invasion (p=0.005). Results: Advanced pathological stage and the presence of a poorly differentiated tumor were independent prognostic factors for OS and CSS. However, advanced pathological stage and perineural invasion were independent predictors of a shorter OS, DFI and CSS. Conclusion: Pathological stage and perineural invasion were the most significant pathological variables in survival analysis in tongue and/or floor of the mouth SCC.

https://doi.org/10.1590/1678-7757-2019-0198 2614 downloads

Riesgo de apendicitis complicada en el paciente diabético
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Ibáñez Morera, Mario

; López Barquero, Hubert

; Medina García, Fernando

; Arias Fallas, Mario Andrés

; Chaves Chaves, Alejandra

; Bolaños Martinez, Isabel

; Jiménez Obando, Luis Diego

Medicina Legal de Costa Rica

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mar 2019, Volume 36 N. 1 Pages 68 - 72

Abstract: Es En | Text: Es En | PDF: Es | PDF: En

Resumen La apendicitis aguda es una de las causas quirúrgicas de dolor abdominal más frecuentes en el mundo. Se presenta en diversos grupos etarios y su presentación clínica puede variar de un grupo a otro. Además hay una variedad de patologías crónicas que pueden opacar la sintomatología usual de la enfermedad, entre ellas la diabetes mellitus. En las últimas décadas la incidencia de diabetes mellitus se ha elevado considerablemente por lo que es más común que un paciente diabético padezca de apendicitis. También, el retraso entre el inicio de los síntomas y el diagnóstico de apendicitis, es un factor de riesgo para el desarrollo de apendicitis aguda complicada. Por ende, es importante conocer tanto las complicaciones como el impacto que puede tener la diabetes mellitus sobre la presentación clínica típica de la apendicitis aguda, para de esta manera, realizar un diagnóstico temprano y preciso.

Abstract Acute Appendicitis is one of the most common surgical causes for abdominal pain in the world. It occurs in a variety of age groups and its clinical presentation vary from one group to another. Additionally, there are several chronic conditions that can blurry the usual symptomatology of the disease, among them diabetes mellitus. In the last decades the incidence of diabetes mellitus has increased considerably, therefore it is more common for a diabetic patient to suffer from appendicitis. Also the delay between the beginning of the symptoms and the diagnosis of appendicitis is a risk factor for the development of complicated acute appendicitis. Thus it is important to know the complications and the impact that diabetes mellitus can have over the clinical presentation of acute appendicitis, thereby an accurate diagnose can be made in the shortest time possible.

Evaluation of Mass Loss in Different Stages of Printed Circuit Boards Recycling Employed in Temperature Controllers
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Schneider, Eduardo Luis

; Hamerski, Fernando

; Veit, Hugo Marcelo

; Krummenauer, Alex

; Cenci, Marcelo Pilotto

; Chaves, Rodrigo de Andrade

; Hartmann, Wagner Luiz

; Dias, Moisés de Mattos

; Robinson, Luiz Carlos

; Vargas, Alexandre Silva de

Materials Research

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2019, Volume 22 elocation e20180833

Abstract: En | Text: En | PDF: En

The aim of this work was to evaluate mass loss in each stage of the recycling process for metal recovery from PCBs of controllers and temperature indicators of cold chambers. The stages of process consists of grinding, particle size classification, magnetic and electrostatic separation. It was analyzed 13 kg of PCBs. These PCBs were crushed and ground. The ground material were subjected to magnetic and electrostatic separator. The losses in the comminution stages were 12.69 % and are lower than those found in other related works that used mixtures of different types of PCBs, whereas in this work only one model plates were analyzed. 27.2 % absolute mass loss we reached out after particle size separation with Tyler Series with 1 mm sieve presents the higher mass losses in the whole process and this fraction was not processed as it results in PCBs powder dust that interferes negatively in the electrostatic separation. Comparing the losses in the stages of shredding of PCBs employed in temperature controllers with other studies involving PCBs from the automotive industry and from computers and cell phones, is remarkable that this type of board presents significantly greater potential to be processed for recovery of its materials.

https://doi.org/10.1590/1980-5373-mr-2018-0833 683 downloads

Volumetría hipocampal: análisis comparativo de los métodos de evaluación en enfermedad de Alzheimer
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Chaves, Hernán

; Rollan, Cecilia Eugenia

; Ventrice, Fernando

; Calandri, Ismael Luis

; Farez, Mauricio Franco

; Yañez, Paulina

Revista argentina de radiología

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jun 2018, Volume 82 N. 2 Pages 57 - 63

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

Objective Hippocampal atrophy is one of the most sensible radiological biomarkers of Alzheimer's disease. There are different methods to evaluate atrophy: visual subjective analysis (VSA), manual objective analysis (MOA) and automatic objective analysis (AOA). We will compare these methods and evaluate if AOA has a confidence similar to MOA (gold standard), and better than VSA. Materials and Methods We retrospectively selected 3D FSPGR MRI from 28 subjects of whom 14 had mild cognitive impairment, 7 Alzheimer's disease and 7 controls. VSA was performed by 10 radiologists who classified hippocampal atrophy in none, mild, moderate and severe. ForMOA, two operatorsmanually segmented both hippocampus from all subjects. AOA was performed by FreeSurfer 5.3. Spearman's rho correlation coefficient was calculated for discrete variables and intraclass correlation coefficient was calculated for continuous variables. Results Correlation coefficients between the operators that performed MOA was 0.88 (p < 0.0001) for left hippocampi and 0.86 (p < 0,0001) for right hippocampi. Correlation coefficients between mean VSA and MOA was-0,81 (95% CI-0,96- -0,66). Correlation coefficients between AOA and AOM was 0.54 (p < 0.0001) for left hippocampi and 0.61 (p < 0.0001) for right hippocampi. Conclusion Even though AOA has moderate correlation with the gold standard it is not superior to average VSA and should be implemented with care in clinical practice.

Objetivo La atrofia hipocampal es uno de los biomarcadores radiológicos más sensibles de la enfermedad de Alzheimer (EA) y existen diferentes métodos para evaluarla: análisis subjetivo visual (ASV), análisis objetivo manual (AOM) y análisis objetivo automático (AOA). Nos proponemos comparar esos métodos, y evaluar si el AOA presenta una confiabilidad cercana al AOM (método de referencia) y superior al ASV. Materiales y Métodos Se seleccionaron retrospectivamente imágenes de resonancia magnética (RM) fast spoiled gradient-echo (FSPGR) de 28 sujetos (14 con deterioro cognitivo leve, 7 con EAy 7 controles). El ASV fue realizado por 10 radiólogos, clasificando la atrofia hipocampal en: nula, leve, moderada o severa. El AOM se basó en la segmentación manual de los hipocampos por dos operadores. El AOA fue realizada por medio del software FreeSurfer 5.3. Se calcularon coeficientes de correlación rho de Spearman para las variables discretas y coeficientes de correlación intraclase para las variables continuas. Resultados Los coeficientes de correlación entre los dos operadores que realizaron el AOM fueron de 0,88 (p < 0,0001) para los hipocampos izquierdos y de 0,86 (p < 0,0001) para los hipocampos derechos. El coeficiente de correlación entre todos los ASV (promediados) y AOM fue de-0,81 (IC 95%-0,96- -0,66). Los coeficientes de correlación entre el AOA y el AOM fue de 0,54 (p < 0,0001) para los hipocampos izquierdos y de 0,61 (p < 0,0001) para los hipocampos derechos. Conclusión Si bien el AOA tiene moderada correlación con el método de referencia, no es superior al ASV promedio y se deberían tomar recaudos antes de ser implementado en la práctica asistencial.

https://doi.org/10.1055/s-0038-1656522 628 downloads

Epónimos en la anatomía y radiología de cabeza y cuello
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Ferraro, Fernando Martín

; Chaves, Hernán

; Olivera Plata, Federico Martín

; Miquelini, Luis Ariel

; Mukherji, Suresh K

Revista argentina de radiología

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jun 2018, Volume 82 N. 2 Pages 72 - 81

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

The use of eponyms in medical language is frequent. While it is commonly thought that eponyms are on their way to extinction, this is not entirely true. There is dissent between those who believe that their use should be abandoned and those who advocate that eponyms make unmemorable terms memorable, convey complex concepts and promote interest in the history of medicine. We feel part of this second group, and our intention is to make a review of eight eponyms linked to head and neck anatomy and radiology. We believe that this approach can be useful for the education of medical students, residents and diagnostic imaging specialists.

En el lenguaje médico, el uso de epónimos es frecuente. Si bien comúnmente se piensa que los epónimos están en vías de extinción, eso no es totalmente cierto. Existe disenso entre quienes creen que su uso debería abandonarse y quienes abogan que los epónimos convierten términos inmemorables en memorizables, transmiten conceptos complejos y promueven el interés en la historia de la Medicina. Nos sentimos parte de ese segundo grupo y nuestra intención es hacer una revisión de ocho epónimos vinculados a la Anatomía y Radiología de cabeza y cuello. Creemos que ese abordaje puede ser útil para la educación de estudiantes de Medicina, residentes y especialistas en diagnóstico por imágenes.

https://doi.org/10.1055/s-0038-1648235 692 downloads

10.

Lipid corneal degeneration after trabeculectomy with mitomicin 0.02%
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Stival, Larissa Rossana Souza

; Chaves, Luis Fernando Oliveira Borges

; Sauter, Karine

; Beniz, Luiz Arthur Franco

; Soares, Jordana Sandes Barbosa

; Rodrigues, Francisco Wellington

; Toledo, Marcia Cristina

; Beniz, José

Revista Brasileira de Oftalmologia

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dec 2016, Volume 75 N. 6 Pages 470 - 472

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Um paciente com história de trabeculectomia com Mitomicina C 0,02%, sem doenças sistêmicas pré-existentes, apresentou infiltrado lipídico corneano unilateral associado à vascularização intraestromal profunda. Injeção subconjuntival de Bevacizumabe foi realizada e posterior ceratoplastia penetrante. Não houve sinais de recorrência em um ano.

ABSTRACT One patient with a history of trabeculectomy with Mitomicin C 0.02%, but no history of systemic disorders, exhibited unilateral corneal lipid infiltrates, together with deep stromal vascularization. She was treated with a bevacizumab injection and penetrating keratoplasty. No sign of recurrence was noted after one year post-operative.

https://doi.org/10.5935/0034-7280.20160094 1261 downloads

11.

Basic sanitation, socioeconomic conditions, and degree of risk for the presence and maintenance of malaria in a low-transmission area in the Brazilian Amazon
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Monteiro, Thais Hetierre Abreu

; Chaves, Tânia do Socorro Souza

; Matos, Haroldo José de

; Sofffiatti, Nelson Fernando de Lisboa

; Guimarães, Ricardo José de Paula Souza e

; Guimarães, Luis Henrique Rocha

; Ventura, Ana Maria Revoredo

; Machado, Ricardo Luiz Dantas

Revista da Sociedade Brasileira de Medicina Tropical

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oct 2015, Volume 48 N. 5 Pages 573 - 579

Abstract: En | Text: En | PDF: En

ABSTRACTINTRODUCTION:This study aimed to evaluate basic sanitation and socioeconomic indicators, reported cases of malaria, and risk of contracting malaria in the Ananindeua municipality, State of Pará.METHODS:Data on basic sanitation and socioeconomic dimensions were taken from the Brazilian Institute of Geography and Statistics [ Instituto Brasileiro de Geografia e Estatística (IBGE)] 2010 census. Epidemiological malaria information was taken from the Epidemiological Malaria Surveillance Information System [ Sistema de Informação de Vigilância Epidemiológica de Malária (SIVEP/Malaria)], between 2003 and 2013 of the Ministry of Health and from the SIVEP/Malaria forms of the municipality's Endemic Diseases Unit for 2,013 cases.RESULTS:Our data do not confirm the correlation among indicators of basic sanitation, socioeconomic conditions, and water supply with malaria cases. Of the 1,557 cases evaluated, most were caused by Plasmodium vivax , with rare cases of Plasmodium falciparum and mixed infections. There were 756 notifications in 2003. The number of reported cases was sharply reduced between 2006 and 2012, but a 142-case outbreak occurred in 2013. Ananindeua municipality's Annual Parasite Index indicated low risk in 2003 and no risk in other years, and the 2,013 cases were predominantly male individuals aged ≥40 years.CONCLUSIONS:Our data confirm the non-endemicity of malaria in the Ananindeua municipality, as the Annual Parasite Indices described for the years 2004-2013 classify it as a risk-free area. However, the 2013 outbreak indicates the need to strengthen prevention, surveillance, and control activities to reduce the risk of new outbreaks and consequent economic and social impacts on the population.

https://doi.org/10.1590/0037-8682-0118-2015 2385 downloads

12.

Características clínicas de los casos de demencia diagnosticados en la Clínica de Memoria del Hospital Nacional de Geriatría y Gerontología
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Miranda-Valverde, Erick

; Valerio-Aguilar, Daniel

; Jacques Hernández-Gabarain, Henri

; Chaves-Araya, Cinthya

; Peralta-Azofeifa, Monserrat

; Corrales-Campos, Luis Emilio

; Córdoba-Moncada, Johan

; Carballo-Alfaro, Ana Maricela

; Morales-Martínez, Fernando

; Arias-Salazar, Alejandra

Acta Médica Costarricense

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sep 2015, Volume 57 N. 3 Pages 130 - 136

Abstract: Es En | Text: Es En | PDF: Es | PDF: En

Antecedentes: la demencia es una entidad clínica cada vez más prevalente en nuestro medio, cuya incidencia aumenta con la edad. El objetivo del presente estudio es identificar los principales tipos de demencia atendidos en una unidad de trastornos de memoria. Métodos: registro consecutivo y estandarizado de pacientes diagnosticados con demencia en la Unidad de Trastornos de Memoria y Conducta, del Hospital Nacional de Geriatría y Gerontología. Resultados: se evaluó 1659 casos, de los cuales el 65,8% reunió criterios de demencia. El 42,9% correspondió a enfermedad de Alzheimer, el 28,5% a demencia secundaria a patología vascular, el 17,1% a formas mixtas, y el 11,5% a tipos varios. La edad media fue de 79,6 + 6,7 años, y el 66,2% fueron mujeres. La escolaridad promedio fue 4,95 + 4,09 años; el 41,7% estaba casado; el 47,3% tenía un hijo como cuidador; el tiempo promedio entre la aparición de los síntomas y el diagnóstico clínico fue de 3,18 + 2,6 años. La puntuación media del test Minimental fue de 18,35 + 5,9 puntos; en el test de dibujo del reloj fue de 3,4 + 2,5, y el Clinical Dementia Rating fue de 1,7 + 0,7; el 45,2% de los casos correspondió a CDR de 1. El 24% de los casos tenía antecedente familiar de demencia, y el 95,7% presentaba uno o más factores de riesgo cardiovascular, siendo la HTA el más frecuente, en un 70,2%. El 27,1% de los casos fue demencias leves; el 31,9%, moderadas; el 39,3% moderadas-severas, y el 1,7%, severas. El 90% de los casos presentó uno o más trastornos neuroconductuales. Conclusiones: la determinación de los principales tipos de demencia en la población adulta mayor y sus principales características, ha permitido registrar gran cantidad de información que se desconocía y que será de útil para la gestión y planificación de estrategias de atención en salud pública.

Background: Dementia is an increasingly prevalent clinical entity in the medical field, whose incidence increases with age. The purpose of this study is to identify the main types of dementia treated in a memory-disorders unit. Methodology: A consecutive and standardized register of patients diagnosed with dementia at the Memory Disorders Unit of the National Geriatrics and Gerontology Hospital. Results: 1659 cases were evaluated, 65.8% met criteria for dementia. 42.9% of the cases were Alzheimer’s disease, 28.5% secondary vascular dementia pathology, mixed forms represented 17.1% and 11.5% were diverse types. The mean age was 79.6 + 6.7 years and 66.2% were women. Average schooling was 4.95+ 4.09 years, 41.7% were married, 47.3% had a child as a caregiver, the average time between onset of symptoms and the clinical diagnosis was 3.18 + 2.6 years. The mean Minimental test score was 18.35 + 5.9 points, in the clock drawing test it was 3.4 + 2.5 and the Clinical Dementia Rating was 1.7 + 0.7; 45.2% of cases were CDR 1. 24% of cases had a family history of dementia and 95.7% had one or more cardiovascular risk factors, with AHT being the most common in 70.2%. 27.1% of dementia cases were mild, 31.9% moderate, 39.3% moderatesevere and 1.7% were severe. 90% of patients had one or more neurobehavioral disorders. Conclusions: The determination of the main types of dementia in the elderly population and their main features has allowed the registry of abundant information that was unknown and that will be useful for the management and strategic planning of public health care.

3349 downloads

13.

Brazilian donkeys (Equus asinus) have a low exposure to Neospora spp.
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Galvão, Cynthia Maria Morais de Queiroz

; Rezende-Gondim, Mariana Marrega

; Chaves, Ana Carla Rodrigues

; Schares, Gereon

; Ribas, Jorge Raimundo Lins

; Gondim, Luís Fernando Pita

Revista Brasileira de Parasitologia Veterinária

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sep 2015, Volume 24 N. 3 Pages 340 - 344

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Asininos (Equus asinus) são próximos filogeneticamente a equinos e podem ser infectados por vários patógenos de cavalos. Neospora caninum e Neospora hughesi são parasitos protozoários que infectam equinos, porém não foram confirmados em asininos até o momento. O objetivo deste estudo foi avaliar a exposição de asininos (Equus asinus) a Neospora spp., usando-se taquizoítos de N. caninum como antígeno e empregando-se duas técnicas sorológicas comuns para esta finalidade, reação de imunofluorescência indireta (RIFI) e immunoblot. Soros de 500 asininos, obtidos em 30 municípios no Estado da Bahia, foram testados por meio da RIFI. Dois dos 500 soros foram positivos para Neospora spp. pela RIFI com títulos de anticorpos de 100, e reconheceram um antígeno de 37kDa no immunoblot. Aproximadamente, 22% das amostras apresentaram fortes reações apicais e/ou fluorescência incompleta, o que pode causar confusão na interpretação da RIFI. Conclui-se que Neospora spp. são, possivelmente, de pouca importância para asininos brasileiros. Estudos posteriores são necessários para provar que Neospora spp. podem causar infecção natural em asininos.

Donkeys (Equus asinus) are closely related to horses and are known to be infected by several equine pathogens. Neospora caninum and Neospora hughesi are protozoan parasites that infect horses, but they were not confirmed in donkeys up to this date. The aim of this study was to evaluate the exposure of donkeys (Equus asinus) to Neospora spp. using tachyzoites of N. caninum as antigen and employing two common serologic methods, IFAT and immunoblot. Sera from 500 donkeys were obtained from 30 municipalities in Bahia state and tested by IFAT. Two of 500 sera were positive for Neospora spp. by IFAT with antibody titers of 100, and recognized a 37kDa antigen in immunoblot. Approximately 22% of the samples showed strong apical reactions and/or incomplete fluorescence, what may cause confusion in the interpretation of IFAT. We concluded that Neospora spp. are possibly of minor importance for Brazilian donkeys. Future studies are necessary to prove that Neospora spp. can naturally infect donkeys.

https://doi.org/10.1590/S1984-29612015057 1447 downloads

14.

O estudo da representação anatômica do músculo latíssimo do dorso e a sua aplicação em cirurgia plástica
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ANDRADE, FERNANDO ANTONIO GOMES DE

; CHAVES, LUCIANO ORNELAS

; CAVALCANTE, CLAUDIO EDUARDO DE OLIVEIRA

; JATOBÁ, IVANADJA

; CUNHA, RAFHAEL MARTINS

; BEZERRA, RICARDO NOGUEIRA

; CALZADO, MAURÍCIO

; BARBOSA, LAÍS CLARK DE CARVALHO

; SALVADOR FILHO, LUÍS HENRIQUE ALVES

; TEIXEIRA, JAMISSON GARROTE

; SILVA, SIMONE VICENTE DIAS DA

Revista Brasileira de Cirurgia Plástica

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jul 2015, Volume 30 N. 3 Pages 345 - 351

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

ABSTRACT Introduction: The latissimus dorsi muscle (LDM) is an important element in the lateroposterior wall of the thorax. The LDM is valued in plastic surgery for its constant anatomy, and its use is recommended for mammary reconstruction, microsurgery, and upper limb reconstruction among other procedures, which makes it a versatile flap for reconstructive surgery. However, its representation in books and anatomical studies is controversial. Mathes & Nahai described that the position of the LDM is configured in a location where the muscle is found in the lateroposterior thoracic segment but with a more posterior than lateral representation. A great number of anatomists share the same opinion. The objective of this study was to discuss and describe the real position of the LDM through study of its anatomy and comparison with images published in books. Methods: We studied the anatomical description and representation of the LDM in drawings published in books and articles by classical authors. The drawings were compared with the neurovascular and muscular anatomy of the LDM during its dissection from 47 fresh cadavers in the dorsal decubitus (DD) position. Results: Study of the anatomical description and representation of the LDM in the revised books compared with the dissection of fresh corpses in the DD position revealed that the published authors described the LDM in a more posterior position than that found in the body. Conclusion: This study identified the LDM position as being more anterior than that described by drawings in published books. LDM rotation and individualization with the patient in a DD position is a safe approach.

RESUMO Introdução: O músculo latíssimo do dorso (MLD) é um importante elemento da parede látero-posterior do tórax. A aplicabilidade do MLD em cirurgia plástica é reconhecida por sua anatomia constante, sendo indicado, na reconstrução mamária, na microcirurgia, nas reconstruções de membros superiores, entre outros, tornando-se um retalho versátil em cirurgia reconstrutora. Sua representação em livros e estudos anatômicos apresentam controvérsias. Mathes & Nahai expressam que a posição do MLD é configurada em uma localização onde o músculo encontra-se em segmento torácico látero-posterior, mas com uma representação mais posterior que lateral. Um grande número de anatomistas escreve da mesma forma. O objetivo é o de discutir e descrever a real posição do MLD por meio do estudo da sua anatomia e comparação com imagens publicadas em livros. Métodos: Estudou-se a descrição e representação anatômica do MLD em desenhos publicados em livros e artigos de autores clássicos. Os desenhos foram comparados com o estudo da anatomia vásculo-nervosa e muscular do MLD durante a dissecção, na posição de Decúbito Dorsal (DD), de 47 cadáveres frescos. Resultados: O estudo da descrição e representação anatômica do MLD em livros de autores consultados, comparada com a dissecção em DD de cadáveres frescos, permitiu conhecer que estes autores identificam o MLD em uma posição mais posterior do que a encontrada na anatomia. Conclusão: Este estudo identifica a posição do MLD com uma representação mais anterior do que os desenhos dos livros estudados. A rotação e individualização do MLD com o paciente em decúbito dorsal é uma abordagem segura.

https://doi.org/10.5935/2177-1235.2015rbcp0163

15.

A sistematização do retalho do músculo latíssimo do dorso em decúbito dorsal
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ANDRADE, FERNANDO ANTÔNIO GOMES DE

; DUARTE, FERNANDO GAIA

; CHAVES, LUCIANO ORNELAS

; BEZERRA, RICARDO NOGUEIRA

; SALVADOR FILHO, LUÍS HENRIQUE ALVES

; SILVA, SIMONE VICENTE DIAS DA

Revista Brasileira de Cirurgia Plástica

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jun 2015, Volume 30 N. 2 Pages 190 - 195

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

ABSTRACT Introduction: The latissimus dorsi muscle is located on the lateral-posterior chest wall. The latissimus dorsi muscle flap (LDMF) has extensive applications due to its consistent anatomy, which contributes to its use in plastic surgery. This muscle can be dissected in the dorsal decubitus (DD) position; this removes the need for a change in patient position and enables microsurgical reconstruction to be performed. This study aimed to describe the technique used for the dissection and transfer of the LDMF in the DD position. Methods: We evaluated 10 cases of LDMF formation performed in the University Hospital of the Federal University of Alagoas. The surgical procedures of individualization of the flaps and their positioning in the receiver region were similar in all ten cases. The evaluation of the muscle and the demarcation of the flap were performed with the patient in the standing position. Then, with the patient in the DD position, anesthetic induction was initiated and the operating field prepared. The neurovascular pedicle was formed by incising the top edge of the ellipse that delimits the LDMF, dissecting the insertion tendon of the muscle, and removing the flap necessary for the reconstruction of the receiver area. Results: The patient was in the DD position during the intraoperative period, even during the dissection of muscle flaps, and the technique used had no surgical disadvantages. Conclusion: It is possible to perform the dissection and individualization of the LDMF with the patient in the DD position.

RESUMO Introdução: O músculo latíssimo do dorso localiza-se na parede latero-posterior do tórax. O retalho do músculo latíssimo do dorso (RMLD) tem uma extensa aplicabilidade devido a sua anatomia pouco variável contribuindo, assim, para sua utilização em Cirurgia Plástica. A possibilidade de dissecar este músculo em decúbito dorsal (DD) dispensa a mudança de posição do paciente e cria uma opção para reconstruções microcirúrgicas. Este estudo objetiva sistematizar a técnica utilizada para dissecção do RMLD em DD. Método: Foram avaliados 10 casos de RMLD realizados no Hospital Universitário da Universidade Federal de Alagoas, os procedimentos cirúrgicos de individualização dos retalhos e seu posicionamento na região receptora foram semelhantes nos dez casos. É realizada a avaliação do músculo e a demarcação do retalho com o paciente em pé. Depois, com o paciente em DD, faz-se a indução anestésica e a preparação do campo a ser operado. Faz a abordagem do pedículo vásculo-nervoso por incisão na margem superior da elipse que delimita o RMLD, secciona o tendão de inserção do músculo e retira-se o retalho necessário à área receptora a ser reconstruída. Resultados: A posição do paciente no intraoperatório foi o DD, inclusive durante a dissecação dos retalhos musculares, e a técnica utilizada não proporcionou desvantagens do ato cirúrgico. Conclusão: É possível realizar a dissecção e individualização do RMLD estando o paciente em DD.

https://doi.org/10.5935/2177-1235.2015rbcp0138

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