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Experimental pain thresholds and psychosocial features across menstrual cycle in myofascial orofacial pain compared to healthy individuals: cross-sectional study
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Herreira-Ferreira, Matheus

; Costa, Yuri Martins

; Cunha, Carolina Ortigosa

; Conti, Ana Claudia de Castro Ferreira

; Conti, Paulo César Rodrigues

; Bonjardim, Leonardo Rigoldi

BrJP

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jun 2023, Volume 6 N. 2 Pages 107 - 112

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

ABSTRACT BACKGROUND AND OBJECTIVES: The hormonal impact on pain perception during the menstrual cycle is a major focus of study, and further elucidation in temporomandibular disorders (TMD) field is necessary. Thus, this cross-sectional study evaluated experimental pain thresholds, psychosocial features, and clinical pain report on TMD women across menstrual cycle versus healthy controls. METHODS: A total of 220 women’s clinical files were screened, with 80 selected and divided into control group (healthy individuals, n=40) and TMD group (myofascial pain, n=40). Regarding the menstrual cycle phases, the files were divided into Pre-Luteal and Luteal. The Perceived Stress Scale (PSS), Pain Catastrophizing Scale (PCS), Mechanical Pain Threshold (MPT), Wind-up (WUR), Pressure Pain Threshold (PPT), Conditioned Pain Modulation (CPM) and Visual Analogue Scale (VAS) were analyzed at a 5% significance level, by Two-Way ANOVA test and post hoc Tukey test. RESULTS: PSS and PCS were significantly different between TMD and control group (p<0.001), regardless of menstrual cycle. Healthy individuals in the Luteal phase presented higher MPT values compared to the other phases (p<0.001). PPT showed significant difference across menstrual phases (p=0.022), but no differences in multiple comparisons. VAS values showed no difference between menstrual cycle phases (p=0.376). CONCLUSION: Finally, healthy individuals in the Luteal phase have higher MPT and PPT values on the orofacial region. Pain report in patients with TMD showed no difference throughout the menstrual cycle, showing that small alterations on experimental pain thresholds may not be clinically relevant. The presence of chronic pain seems to be more related to psychosocial features than hormonal fluctuations.

RESUMO JUSTIFICATIVA E OBJETIVOS: O impacto do ciclo menstrual na percepção da dor é um foco importante de estudo, sendo necessária uma maior elucidação na disfunção temporomandibular (DTM). Assim, este estudo transversal avaliou limiares de dor experimental, características psicossociais e relatos de dor em mulheres com DTM ao longo do ciclo menstrual, comparadas com controles saudáveis. MÉTODOS: 220 prontuários de mulheres foram analisados, sendo 80 selecionados para os grupos de controle (saudáveis, n=40) e DTM (dor miofascial, n=40). Nas fases do ciclo menstrual, as pacientes foram divididas nas categorias Pré-Luteal e Luteal. Os instrumentos Escala de Estresse Percebido (PSS), Escala de Pensamentos Catastróficos (PCS), Limiar de Dor Mecânica (MPT), Wind-up Ratio (WUR), Limiar de Dor à Pressão (PPT), Modulação Condicionada da Dor (CPM) e Escala analógica visual (EAV) foram analisados com nível de significância de 5%, pelos testes ANOVA de dois fatores e Tukey post hoc. RESULTADOS: As escalas PSS e PCS foram significativamente diferentes entre os grupos DTM e controle (p<0,001), independentemente do ciclo menstrual. Indivíduos saudáveis na fase luteal apresentaram MPT maior em comparação com outras fases (p,0,001). O PPT mostrou diferença significativa entre as fases menstruais (p=0,022), sem diferença nas comparações múltiplas. Os valores da EAV não apresentaram diferença entre as fases menstruais (p=376). CONCLUSÃO: Indivíduos saudáveis na fase luteal têm MPT e PPTl maior na região orofacial. Os relatos de dor em pacientes com DTM não mostraram diferença ao longo do ciclo menstrual, indicando que pequenas alterações nos limiares experimentais podem ser clinicamente relevantes. A presença de dor crônica parece estar mais relacionada com características psicossociais do que com flutuações hormonais.

https://doi.org/10.5935/2595-0118.20230033-en

COVID-19 outcomes in people living with HIV: Peering through the waves
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Sales, Thaís Lorenna Souza

; Souza-Silva, Maíra Viana Rego

; Delfino-Pereira, Polianna

; Neves, João Victor Baroni

; Sacioto, Manuela Furtado

; Assis, Vivian Costa Morais de

; Duani, Helena

; Oliveira, Neimy Ramos de

; Sampaio, Natália da Cunha Severino

; Ramos, Lucas Emanuel Ferreira

; Schwarzbold, Alexandre Vargas

; Jorge, Alzira de Oliveira

; Scotton, Ana Luiza Bahia Alves

; Castro, Bruno Mateus de

; Silva, Carla Thais Cândida Alves da

; Ramos, Carolina Marques

; Anschau, Fernando

; Botoni, Fernando Antonio

; Grizende, Genna Maira Santos

; Nascimento, Guilherme Fagundes

; Ruschel, Karen Brasil

; Menezes, Luanna Silva Monteiro

; Castro, Luís César de

; Nasi, Luiz Antônio

; Carneiro, Marcelo

; Godoy, Mariana Frizzo de

; Nogueira, Matheus Carvalho Alves

; Guimarães Júnior, Milton Henriques

; Ziegelmann, Patricia Klarmann

; Almeida, Rafaela Charão de

; Francisco, Saionara Cristina

; Silveira Neto, Sidney Teodoro

; Araújo, Silvia Ferreira

; Avelino-Silva, Thiago Junqueira

; Aliberti, Márlon Juliano Romero

; Pires, Magda Carvalho

; Silva, Eduardo Sérgio da

; Marcolino, Milena Soriano

Clinics

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2023, Volume 78 elocation 100223

Abstract: En | Text: En | PDF: En

Abstract Objective To evaluate clinical characteristics and outcomes of COVID-19 patients infected with HIV, and to compare with a paired sample without HIV infection. Methods This is a substudy of a Brazilian multicentric cohort that comprised two periods (2020 and 2021). Data was obtained through the retrospective review of medical records. Primary outcomes were admission to the intensive care unit, invasive mechanical ventilation, and death. Patients with HIV and controls were matched for age, sex, number of comorbidities, and hospital of origin using the technique of propensity score matching (up to 4:1). They were compared using the Chi-Square or Fisher's Exact tests for categorical variables and the Wilcoxon for numerical variables. Results Throughout the study, 17,101 COVID-19 patients were hospitalized, and 130 (0.76%) of those were infected with HIV. The median age was 54 (IQR: 43.0;64.0) years in 2020 and 53 (IQR: 46.0;63.5) years in 2021, with a predominance of females in both periods. People Living with HIV (PLHIV) and their controls showed similar prevalence for admission to the ICU and invasive mechanical ventilation requirement in the two periods, with no significant differences. In 2020, in-hospital mortality was higher in the PLHIV compared to the controls (27.9% vs. 17.7%; p = 0.049), but there was no difference in mortality between groups in 2021 (25.0% vs. 25.1%; p > 0.999). Conclusions Our results reiterate that PLHIV were at higher risk of COVID-19 mortality in the early stages of the pandemic, however, this finding did not sustain in 2021, when the mortality rate is similar to the control group.

https://doi.org/10.1016/j.clinsp.2023.100223

Hemophagocytic lymphohistiocytosis and visceral leishmaniasis in children: a series of cases and literature review
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Brum, Natália Fernanda Ferreira

; Coelho, Julia Sampaio

; Carvalho, Laís Silva

; Vieira, Matheus Nascimento Otoni

; Bentes, Aline Almeida

; Carellos, Ericka Viana Machado

; Diniz, Lilian Martins Oliveira

; Carvalho, Andrea Lucchesi de

; Romanelli, Roberta Maia de Castro

Revista Paulista de Pediatria

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2022, Volume 40 elocation e2020269

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Objetivo: Linfo-histiocitose hemofagocítica (LHH) é uma síndrome caracterizada pela hiperativação de linfócitos T citotóxicos, células natural killer e macrófagos, levando à secreção de citocinas pró-inflamatórias. Linfo-histiocitose hemofagocítica associada a Leishmaniose Visceral é um quadro de grande desafio para o diagnóstico, considerando que os sintomas são semelhantes, podendo levar ao óbito pacientes não tratados. Nosso objetivo é descrever uma série de casos de Leishmaniose Visceral com LHH admitidos em um hospital de referência para doenças infecciosas. Descrição do caso: Todos os 115 casos de Leishmaniose Visceral encaminhados ao centro de referência em doenças infecciosas pediátricas foram revistos para identificar os casos de LHH. Cinco casos (4,5%) foram confirmados com LHH e apresentaram febre, esplenomegalia, citopenia, hipertrigliceridemia ou hipofibrinogenemia, aumento de ferritina e hemafagocitose em medula óssea. Comentários: Deve-se suspeitar de LHH em crianças com doenças infecciosas que não respondem adequadamente ao tratamento ou em pacientes com sintomas graves, principalmente em áreas endêmicas da leishmaniose.%

ABSTRACT Objective: Hemophagocytic lymphohistiocytosis syndrome (HLHS) is characterized by an immunological hyperactivation of cytotoxic T cells, natural killer cells, and macrophages, leading to the secretion of proinflammatory cytokines. HLHS associated with Visceral Leishmaniasis might be difficult to diagnose once symptoms are similar, resulting in the death of untreated patients. Our aim is to describe a series of cases of Visceral Leishmaniasis with HLHS admitted to a referral hospital for infectious diseases. Case description: All 115 cases of Visceral Leishmaniasis referred to a referral center for pediatric infectious diseases were reviewed to identify the cases of HLHS. Five cases (4.5%) were confirmed with HLHS and they presented fever, splenomegaly, cytopenia, hypertriglyceridemia or hypofibrinogenemia, increased ferritin and hemophagocytosis in the bone marrow. Comments: It important to rule out HLHS in children with infectious diseases that do not respond adequately to treatment or in patients with severe symptoms, especially in leishmaniasis endemic areas.%

https://doi.org/10.1590/1984-0462/2022/40/2020269 168 downloads

Development and characterization of PLGA-Bupivacaine and PLGA-S75:R25 Bupivacaine (Novabupi®) biodegradable implants for postoperative pain
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Castro, Matheus Augusto de

; Cunha, Gabriella Maria Fernandes

; Andrade, Gracielle Ferreira

; Yoshida, Maria Irene

; Faria, Ana Luiza de

; Silva-Cunha, Armando

Brazilian Journal of Pharmaceutical Sciences

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2022, Volume 58 elocation e21310

Abstract: En | Text: En | PDF: En

Abstract In the hospital environment, postoperative pain is a common occurrence that impairs patient recovery and rehabilitation and lengthens hospitalization time. Racemic bupivacaine hydrochloride (CBV) and Novabupi® (NBV) (S (-) 75% R (+) 25% bupivacaine hydrochloride) are two examples of local anesthetics used in pain management, the latter being an alternative with less deleterious effects. In the present study, biodegradable implants were developed using Poly(L-lactide-co-glycolide) through a hot molding technique, evaluating their physicochemical properties and their in vitro drug release. Different proportions of drugs and polymer were tested, and the proportion of 25%:75% was the most stable for molding the implants. Thermal and spectrometric analyses were performed, and they revealed no unwanted chemical interactions between drugs and polymer. They also confirmed that heating and freeze-drying used for manufacturing did not interfere with stability. The in vitro release results revealed drugs sustained release, reaching 64% for NBV-PLGA and 52% for CBV-PLGA up to 30 days. The drug release mechanism was confirmed by microscopy, which involved pores formation and polymeric erosion, visualized in the first 72 h of the in vitro release test. These findings suggest that the developed implants are interesting alternatives to control postoperative pain efficiently.

https://doi.org/10.1590/s2175-97902022e21310

First record of Blankaartia sinnamaryi (Floch & Fauran, 1956) (Trombidiformes: Trombiculidae) parasitizing the striped owl in Northeastern Brazil
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Bassini-Silva, Ricardo

; Jacinavicius, Fernando de Castro

; Huang-Bastos, Matheus

; Batista, Aksa Ingrid Vieira

; Silva, Nathália Caroline Souza da

; Nery, Thiago Ferreira Lopes

; Pereira, Josivania Soares

; Welbourn, Cal

; Ochoa, Ron

; Barros-Battesti, Darci Moraes

Revista Brasileira de Parasitologia Veterinária

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2021, Volume 30 N. 3 elocation e003121

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo A espécie de trombiculídeo, Blankaartia sinnamaryi (Floch & Fauran) tem sido coletada principalmente parasitando aves, com alguns registros em répteis e mamíferos. No Brasil, essa espécie foi encontrada em aves nos estados de Minas Gerais e Rio de Janeiro. No presente estudo, relatamos o primeiro registro de B. sinnamaryi parasitando a coruja-listrada, Pseudoscops clamator (Vieillot), no estado da Paraíba, Brasil (região Nordeste).

Abstract The chigger species Blankaartia sinnamaryi (Floch & Fauran) has been collected mainly from birds with a few records from reptiles and mammals. In Brazil, this species has been found on birds in the Minas Gerais and Rio de Janeiro states. Here, we report the first record of B. sinnamaryi parasitizing the striped owl, Pseudoscops clamator (Vieillot), in the Paraíba state, Brazil (northeastern region).

https://doi.org/10.1590/s1984-29612021042 155 downloads

Neurological consultations and diagnoses in a large, dedicated COVID-19 university hospital
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STUDART-NETO, Adalberto

; GUEDES, Bruno Fukelmann

; TUMA, Raphael de Luca e

; CAMELO FILHO, Antonio Edvan

; KUBOTA, Gabriel Taricani

; IEPSEN, Bruno Diógenes

; MOREIRA, Gabriela Pantaleão

; RODRIGUES, Júlia Chartouni

; FERRARI, Maíra Medeiros Honorato

; CARRA, Rafael Bernhart

; SPERA, Raphael Ribeiro

; OKU, Mariana Hiromi Manoel

; TERRIM, Sara

; LOPES, Cesar Castello Branco

; PASSOS NETO, Carlos Eduardo Borges

; FIORENTINO, Matheus Dalben

; DE SOUZA, Julia Carvalhinho Carlos

; BAIMA, José Pedro Soares

; DA SILVA, Tomás Fraga Ferreira

; MORENO, Cristiane Araujo Martins

; SILVA, Andre Macedo Serafim

; HEISE, Carlos Otto

; MENDONÇA, Rodrigo Holanda

; FORTINI, Ida

; SMID, Jerusa

; ADONI, Tarso

; GONÇALVES, Marcia Rubia Rodrigues

; PEREIRA, Samira Luisa Apóstolos

; PINTO, Lecio Figueira

; GOMES, Helio Rodrigues

; ZANOTELI, Edmar

; BRUCKI, Sonia Maria Dozzi

; CONFORTO, Adriana Bastos

; CASTRO, Luiz Henrique Martins

; NITRINI, Ricardo

Arquivos de Neuro-Psiquiatria

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aug 2020, Volume 78 N. 8 Pages 494 - 500

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Introdução: Mais de um terço dos pacientes com COVID-19 apresentam sintomas neurológicos que variam de anosmia a AVC e encefalopatia. Além disso, doenças neurológicas prévias podem exigir tratamento especial e estar associadas a piores desfechos. Não obstante, o papel dos neurologistas na COVID-19 é provavelmente pouco reconhecido. Objetivo: O objetivo deste estudo foi relatar os motivos para solicitar consultas neurológicas por clínicos e intensivistas em um hospital dedicado à COVID-19. Métodos: Estudo retrospectivo realizado no Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, Brasil, um centro dedicado à COVID-19 com 900 leitos (incluindo 300 leitos para unidades de terapia intensiva). O diagnóstico de COVID-19 foi confirmado por SARS-CoV-2-RT-PCR em swabs nasais. Todas as interconsultas de neurologia hospitalar entre 23 de março e 23 de maio de 2020 foram analisadas. Os neurologistas realizaram o exame neurológico, avaliaram todos os dados disponíveis para diagnosticar a patologia neurológica e solicitaram exames adicionais conforme necessidade. Diagnósticos difíceis foram estabelecidos em reuniões de consenso. Após o diagnóstico, os neurologistas participaram da condução dos casos. Resultados: Foram solicitadas consultas neurológicas para 89 de 1.208 (7,4%) em pacientes internados por COVID-19 durante o período. Os principais diagnósticos neurológicos incluíram: encefalopatia (44,4%), acidente vascular cerebral (16,7%), doenças neurológicas prévias (9,0%), crises epilépticas (9,0%), transtornos neuromusculares (5,6%), outras lesões encefálicas agudas (3,4%) e outros sintomas leves inespecíficos (11,2%). Conclusões: A maioria das consultas neurológicas em um hospital dedicado à COVID-19 foi solicitada para condições graves que poderiam afetar o desfecho clínico. Os médicos na linha de frente devem ser capazes de reconhecer sintomas neurológicos. Os neurologistas são membros importantes da equipe médica no atendimento hospitalar à COVID-19.

ABSTRACT Background: More than one-third of COVID-19 patients present neurological symptoms ranging from anosmia to stroke and encephalopathy. Furthermore, pre-existing neurological conditions may require special treatment and may be associated with worse outcomes. Notwithstanding, the role of neurologists in COVID-19 is probably underrecognized. Objective: The aim of this study was to report the reasons for requesting neurological consultations by internists and intensivists in a COVID-19-dedicated hospital. Methods: This retrospective study was carried out at Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, Brazil, a 900-bed COVID-19 dedicated center (including 300 intensive care unit beds). COVID-19 diagnosis was confirmed by SARS-CoV-2-RT-PCR in nasal swabs. All inpatient neurology consultations between March 23rd and May 23rd, 2020 were analyzed. Neurologists performed the neurological exam, assessed all available data to diagnose the neurological condition, and requested additional tests deemed necessary. Difficult diagnoses were established in consensus meetings. After diagnosis, neurologists were involved in the treatment. Results: Neurological consultations were requested for 89 out of 1,208 (7.4%) inpatient COVID admissions during that period. Main neurological diagnoses included: encephalopathy (44.4%), stroke (16.7%), previous neurological diseases (9.0%), seizures (9.0%), neuromuscular disorders (5.6%), other acute brain lesions (3.4%), and other mild nonspecific symptoms (11.2%). Conclusions: Most neurological consultations in a COVID-19-dedicated hospital were requested for severe conditions that could have an impact on the outcome. First-line doctors should be able to recognize neurological symptoms; neurologists are important members of the medical team in COVID-19 hospital care.

https://doi.org/10.1590/0004-282x20200089 2651 downloads

[SciELO Preprints] - Neurological consultations and diagnoses in a large, dedicated COVID-19 university hospital
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Studart-Neto, Adalberto Guedes, Bruno Fukelmann Tuma, Raphael De Luca E Camelo Filho, Antonio Edvan Kubota, Gabriel Taricani Iepsen, Bruno Diógenes Moreira, Gabriela Pantaleão Rodrigues, Júlia Chartouni Ferrari, Maíra Medeiros Honorato Carra, Rafael Bernhard Spera, Raphael Ribeiro Oku, Mariana Hiromi Manoel Terrim, Sara Lopes, Cesar Castello Branco Passos Neto, Carlos Eduardo Borges Dalben, Matheus De Souza, Julia Carvalhinho Carlos Baima, José Pedro Soares Da Silva, Tomás Fraga Ferreira Moreno, Cristiane Araujo Martins Silva, Andre Macedo Serafim Heise, Carlos Otto Mendonça, Rodrigo Holanda Fortini, Ida Smid, Jerusa Adoni, Tarso Gonçalves, Marcia Rubia Rodrigues Pereira, Samira Luisa Apóstolos Pinto, Lecio Figueira Gomes, Helio Rodrigues Zanotelli, Edmar Brucki, Sonia Maria Dozzi Conforto, Adriana Bastos Castro, Luiz Henrique Martins Nitrini, Ricardo

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Publication date: 2020-07-16

Abstract: En Pt

Background: More than one-third of COVID-19 patients present neurological symptomsranging from anosmia to stroke and encephalopathy. Furthermore, pre-existingneurological conditions may require special treatment and may be associated with worseoutcomes. Notwithstanding, the role of neurologists in COVID-19 is probablyunderrecognized. Objective: The aim of this study was to report the reasons forrequesting neurological consultations by internists and intensivists in a COVID-19-dedicated hospital. Methods: This retrospective study was carried out at Hospital dasClínicas da Faculdade de Medicina da Universidade de São Paulo, Brazil, a 900-bedCOVID-19 dedicated center (including 300 intensive care unit beds). COVID-19 diagnosiswas confirmed by SARS-CoV-2-RT-PCR in nasal swabs. All inpatient neurologyconsultations between March 23rd and May 23rd, 2020 were analyzed. Neurologistsperformed the neurological exam, assessed all available data to diagnose theneurological condition, and requested additional tests deemed necessary. Difficultdiagnoses were established in consensus meetings. After diagnosis, neurologists wereinvolved in the treatment. Results: Neurological consultations were requested for 89 outof 1,208 (7.4%) inpatient COVID admissions during that period. Main neurologicaldiagnoses included: encephalopathy (44.4%), stroke (16.7%), previous neurologicaldiseases (9.0%), seizures (9.0%), neuromuscular disorders (5.6%), other acute brainlesions (3.4%), and other mild nonspecific symptoms (11.2%). Conclusions: Mostneurological consultations in a COVID-19-dedicated hospital were requested for severeconditions that could have an impact on the outcome. First-line doctors should be able torecognize neurological symptoms; neurologists are important members of the medicalteam in COVID-19 hospital care.

Introdução: Mais de um terço dos pacientes com COVID-19 apresentam sintomasneurológicos que variam de anosmia a AVC e encefalopatia. Além disso, doençasneurológicas prévias podem exigir tratamento especial e estar associadas a pioresdesfechos. Não obstante, o papel dos neurologistas na COVID-19 é provavelmentepouco reconhecido. Objetivo: O objetivo deste estudo foi relatar os motivos para solicitarconsultas neurológicas por clínicos e intensivistas em um hospital dedicado à COVID-19. Métodos: Estudo retrospectivo realizado no Hospital das Clínicas da Faculdade deMedicina da Universidade de São Paulo, Brasil, um centro dedicado à COVID-19 com900 leitos (incluindo 300 leitos para unidades de terapia intensiva). O diagnóstico deCOVID-19 foi confirmado por SARS-CoV-2-RT-PCR em swabs nasais. Todas asinterconsultas de neurologia hospitalar entre 23 de março e 23 de maio de 2020 foramanalisadas. Os neurologistas realizaram o exame neurológico, avaliaram todos os dadosdisponíveis para diagnosticar a patologia neurológica e solicitaram exames adicionaisconforme necessidade. Diagnósticos difíceis foram estabelecidos em reuniões deconsenso. Após o diagnóstico, os neurologistas participaram da condução dos casos.Resultados: Foram solicitadas consultas neurológicas para 89 de 1.208 (7,4%) empacientes internados por COVID-19 durante o período. Os principais diagnósticosneurológicos incluíram: encefalopatia (44,4%), acidente vascular cerebral (16,7%),doenças neurológicas prévias (9,0%), crises epilépticas (9,0%), transtornosneuromusculares (5,6%), outras lesões encefálicas agudas (3,4%) e outros sintomasleves inespecíficos (11,2%). Conclusões: A maioria das consultas neurológicas em umhospital dedicado à COVID-19 foi solicitada para condições graves que poderiam afetaro desfecho clínico. Os médicos na linha de frente devem ser capazes de reconhecersintomas neurológicos. Os neurologistas são membros importantes da equipe médica noatendimento hospitalar à COVID-19.

https://doi.org/10.1590/0004-282X20200089

Teorizar, repetir e patologizar: a leitura psicanalítica sobre as homossexualidades e transexualidades
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Almeida, Pedro Teixeira de

; Castro, Matheus Ferreira de

; Ribeiro, Sarug Dagir

Revista Latinoamericana de Psicopatologia Fundamental

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mar 2020, Volume 23 N. 1 Pages 77 - 98

O objetivo deste trabalho é localizar o entrecruzamento dos elementos comuns ou que se repetem nas teorizações psicanalíticas em torno da homossexualidade e da transexualidade. Passando pela caracterização dos discursos psicanalíticos desde Freud e Lacan até nossos dias, constatamos uma espécie de repetição nessas teorizações, uma vez que a homossexualidade foi historicamente atrelada a uma escolha de objeto narcísica e à perversão, fato que se repete na contemporaneidade em postulações sobre as transexualidades, tidas como psicose e perversão. Conclui-se que muitos textos psicanalíticos se articulam, se entrelaçam e se suplementam numa repetição de teorizações como a tese do hermafroditismo psíquico que serve de base etiológica tanto para as homossexualidades como para as transexualidades.

This work aims to localize the intertwining of common or repeated elements in psychoanalytic theorizations about homosexuality and transsexuality. By characterizing psychoanalytic discourses from Freud and Lacan to our days, we find a kind of repetition in these theorizations, since homosexuality has historically been associated to a choice of narcissistic object and perversion, a fact that is repeated nowadays in postulations about transsexualities, which are described as psychosis and perversion. We conclude that a large number of psychoanalytic texts are linked, intertwined and informed by repeating theories such as the thesis of psychic hermaphroditism that serves as the etiological basis for both homosexualities and transsexualities.

El objetivo de este trabajo es localizar el entrecruzamiento de los elementos comunes o que se repiten en las teorizaciones psicoanalíticas sobre la homosexualidad y la transexualidad. Desde la caracterización de los discursos psicoanalíticos desde Freud y Lacan hasta nuestros días, hemos constatado una especie de repetición en estas teorizaciones, ya que la homosexualidad ha estado históricamente vinculada a una elección narcisista de objeto y a la perversión, un hecho que se repite en la actualidad en las postulaciones sobre las Transexualidades, vistas como psicosis y perversión. Se concluye que muchos textos psicoanalíticos se articulan, entrelazan y complementan en una repetición de teorías como la tesis del hermafroditismo psíquico que sirve como base etiológica tanto para la homosexualidad como para la transexualidad.

L’objectif de ce travail est de localiser le métissage des éléments communs ou répétés dans les théories psychanalytiques autour de l’homosexualité et de la transsexualité. La caractérisation des discours psychanalytiques depuis Freud et Lacan jusqu’à aujourd’hui consiste en une sorte de répétition dans ces théories, étant donné que l’homosexualité a toujours été liée au choix de l’objet narcissique et à la perversion, fait qui se reproduit aujourd’hui dans des postulats sur les transsexualités, prises comme psychose et perversion. Nous concluons que de nombreux textes psychanalytiques sont liés, entrelacés et complétés par une répétition de théories telles que la thèse de l’hermaphrodisme psychique qui sert de base étiologique à la fois à l’homosexualité et à la transsexualité.

https://doi.org/10.1590/1415-4714.2020v23n1p77.6 1509 downloads

Comportamento de Juntas Soldadas de Aço C-Mn Obtidas Pelo Processo GMAW-RE com Eletrodo Rotativo
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Costa, Jeferson Frederico Monteiro

; Silva Filho, Walker Andrade da

; Silveira, Guilherme Mastrange dos Santos

; Almeida, Felipe Augusto de Castro

; Lobato, Marcos Muller

; Chuvas, Tatiane de Campos

; Mendes, Matheus Campolina

; Souza, Luís Felipe Guimarães de

; Jorge, Jorge Carlos Ferreira

Soldagem & Inspeção

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2019, Volume 24 elocation e2411

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo O presente trabalho tem como objetivo estudar o comportamento de juntas soldadas obtidas pelo processo GMAW com eletrodo rotativo (GMAW-RE), de modo a permitir uma análise comparativa de produtividade e propriedades mecânicas com o processo GMAW convencional (GMAW). Foram realizadas soldagens multipasse pelos dois processos GMAW com preaquecimento de 100 °C em chapas de dimensões 500 × 150 × 10 mm em aço ASTM A36, na posição plana e energia de soldagem média de 2,30 kJ/mm. Após a soldagem, foram realizados ensaios de impacto Charpy-V, microdureza e metalográficos em corpos-de-prova removidos transversalmente ao cordão de solda. Adicionalmente, foi realizada uma análise comparativa de produtividade entre os processos. Os resultados mostram que o processo GMAW-RE propicia um aumento de produtividade e redução de custos significativos em relação ao processo GMAW. Adicionalmente, foram observados valores equivalentes de tenacidade ao impacto para o metal de solda, mas uma redução nesta propriedade na zona termicamente afetada. Embora a literatura disponível destaque o elevado potencial deste processo para substituição do processo GMAW convencional em aplicações industriais, verifica-se a necessidade de mais evidências experimentais para um maior suporte a esta indicação.

Abstract The main goal of the present work is to evaluate the behavior of welded joints obtained by the GMAW with rotating electrode process (GMAW-RE) in comparison to the Conventional GMAW process (GMAW). Multipass welding by both processes were performed in ASTM A36 steel plates with dimensions of 500 × 150 × 10 mm, preheating of 100 °C in the flat position and average welding energy of 2.30kJ/mm. After welding, Charpy-V notch and microhardness tests and metallographic examination were performed in samples removed transversally to the weld bead. Additionally, a comparative analysis of productivity and costs between processes were done. The results show that the GMAW-RE promotes higher productivity and reduction of costs in comparison to GMAW. Additionally, similar impact toughness results were observed in weld metals and a reduction on this property at the HAZ. Although the literature states the high potential of the GMAW-RE for replacement of the conventional GMAW in industrial applications, it was concluded that other experimental results are still necessary before the final conclusion.

https://doi.org/10.1590/0104-9224/si24.11 1457 downloads

10.

A proposal of Brazilian Society of Surgical Oncology (BSSO/SBCO) for standardizing cytoreductive surgery (CRS) plus hyperthermic intraperitoneal chemotherapy (HIPEC) procedures in Brazil: pseudomixoma peritonei, appendiceal tumors and malignant peritoneal mesothelioma
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Batista, Thales Paulo

; Sarmento, Bruno José Queiroz

; Loureiro, Janina Ferreira

; Petruzziello, Andrea

; Lopes, Ademar

; Santos, Cassio Cortez

; Quadros, Cláudio de Almeida

; Akaishi, Eduardo Hiroshi

; Cordeiro, Eduardo Zanella

; Coimbra, Felipe José Fernández

; Laporte, Gustavo Andreazza

; Castro, Leonaldson Santos

; Batista, Ranyell Matheus Spencer Sobreira

; Aguiar Júnior, Samuel

; Costa Júnior, Wilson Luiz

; Ferreira, Fábio Oliveira

Revista do Colégio Brasileiro de Cirurgiões

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oct 2017, Volume 44 N. 5 Pages 530 - 544

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO A cirurgia citorredutora com quimioterapia intraperitoneal hipertérmica emergiu como um importante tratamento das neoplasias peritoneais e é, atualmente, o padrão de atendimento para neoplasias epiteliais do apêndice associadas à síndrome de pseudomixoma peritoneal, bem como para o mesotelioma peritoneal maligno difuso. No mundo, existem algumas variações reconhecidas das técnicas de cirurgia citorredutora e quimioterapia intraperitoneal hipertérmica, entretanto nenhuma técnica até agora demonstrou sua superioridade sobre o outra. Portanto, a padronização destes procedimentos poderia melhorar a prática clínica e permitir a comparação adequada entre os resultados. Neste cenário, a Sociedade Brasileira de Cirurgia Oncológica considera importante a apresentação de uma proposta de padronização de procedimentos de cirurgia citorredutora com quimioterapia intraperitoneal hipertérmica no Brasil, com um foco especial na produção de dados homogêneos para o desenvolvimento do registro brasileiro das neoplasias peritoneais.

ABSTRACT Cytoreductive surgery plus hypertermic intraperitoneal chemotherapy has emerged as a major comprehensive treatment of peritoneal malignancies and is currently the standard of care for appendiceal epithelial neoplasms and pseudomyxoma peritonei syndrome as well as malignant peritoneal mesothelioma. Unfortunately, there are some worldwide variations of the cytoreductive surgery and hypertermic intraperitoneal chemotherapy techniques since no single technique has so far demonstrated its superiority over the others. Therefore, standardization of practices might enhance better comparisons between outcomes. In these settings, the Brazilian Society of Surgical Oncology considered it important to present a proposal for standardizing cytoreductive surgery plus hypertermic intraperitoneal chemotherapy procedures in Brazil, with a special focus on producing homogeneous data for the developing Brazilian register for peritoneal surface malignancies.

https://doi.org/10.1590/0100-69912017005016 9183 downloads

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