Results: 37
#1
au:Cardoso, Daniel Rodrigues
Filters
Order by
Page
of 3
Next
1.
Cost-effectiveness analysis of cinacalcet vs. paricalcitol in the treatment of hyperparathyroidism secondary to chronic kidney disease
Facebook Twitter
Facebook Twitter
- Other social networks
- Google+
- StambleUpon
- CiteULike
- Mendeley
- Other networks
- Metrics
Ponce, Daniela
; Cardoso, Marilia Mastrocolla de Almeida
; Rúgolo, Juliana Rodrigues Machado
; Molina, Silvana Andrea
; Andrade, Luis Gustavo Modelli de
; Curado, Daniel da Silva Pereira
.
ABSTRACT Introduction For the reduction of PTH levels, two classes of drugs are available in the Brazilian market: non-selective and selective vitamin D receptor activators and calcimimetics. Among the mentioned drugs, the SUS provides oral calcitriol, paricalcitol and cinacalcet. Objectives: Develop cost-effectiveness (CE) and budgetary impact (BI) analysis of cinacalcet versus paricalcitol for patients on dialysis with SHPT, from the perspective of SUS. Methodology: A decision tree model was constructed for CE analysis, which considered the outcome of avoided parathyroidectomy and a time horizon of 1 year. As for the BI analysis, two scenarios were considered, one of which was measured demand and other epidemiological, based on data from the Brazilian Society of Nephrology (BSN). Results: The CE analysis showed that the use of cinacalcet results in one-off savings of R$1,394.64 per year and an incremental effectiveness of 0.08, in relation to avoided parathyroidectomy. The incremental CE ratio (ICER) was - R$ 17,653.67 per avoided parathyroidectomy for cinacalcet, as it was more effective and cheaper compared to paricalcitol. As for the BI analysis, it was estimated that the incremental BI with the expansion of the use of cinacalcet in the SUS will be between - R$ 1,640,864.62 and R$ 166,368.50 in the first year, considering the main and the epidemiological scenarios. At the end of 5 years after the expansion of use, an BI was estimated between - R$ 10,740,743.86 and - R$ 1,191,339.37; considering the same scenarios. Conclusion: Cinacalcet was dominant to avoid parathyroidectomies, being cost-effective.
RESUMO Introdução: Para a redução dos níveis do paratormônio (PTH) estão disponíveis no mercado brasileiro duas classes de medicamentos: ativadores do receptor da vitamina D (não seletivos e seletivos) e calcimiméticos. Dentre os medicamentos supracitados, o SUS disponibiliza calcitriol oral, paricalcitol e cinacalcete. Objetivos: Desenvolver análise de custo-efetividade (CE) e de impacto orçamentário (IO) do cinacalcete versus paricalcitol para pacientes em diálise com HPTS, na perspectiva do SUS. Metodologia: Foi construído um modelo de árvore de decisão para a análise de CE, que considerou o desfecho paratireoidectomia evitada e um horizonte temporal de 1 ano. Quanto à análise de IO, foram considerados dois cenários, um de demanda aferida e outro de abordagem epidemiológica, baseado nos dados da Sociedade Brasileira de Nefrologia (SBN). Resultados: A análise de CE mostrou que o uso de cinacalcete resulta em economia de R$ 1.394,64 ao ano e efetividade incremental de 0,08, em relação a paratireoidectomia evitada. A razão de CE incremental (RCEI) foi de - R$ 17.653,67 por paratireoidectomia evitada para o cinacalcete, já que se mostrou mais efetivo e mais barato comparado ao paricalcitol. Estimou-se que o IO incremental com a ampliação do uso do cinacalcete no SUS estará entre - R$ 1.640.864,62 e R$ 166.368,50 no primeiro ano, considerando os cenários principal e epidemiológico baseado nos dados da SBN. Já ao final de 5 anos após a ampliação do uso, estimou-se um impacto incremental entre - R$ 10.740.743,86 e - R$ 1.191.339,37; considerando os mesmos cenários. Conclusão: Cinacalcete foi dominante para evitar paratireoidectomias, sendo custo-efetivo.
2.
Cost-effectiveness analysis of cinacalcet vs. paricalcitol in the treatment of hyperparathyroidism secondary to chronic kidney disease
Facebook Twitter
Facebook Twitter
- Other social networks
- Google+
- StambleUpon
- CiteULike
- Mendeley
- Other networks
- Metrics
Ponce, Daniela
; Cardoso, Marilia Mastrocolla de Almeida
; Rúgolo, Juliana Rodrigues Machado
; Molina, Silvana Andrea
; Andrade, Luis Gustavo Modelli de
; Curado, Daniel da Silva Pereira
.
RESUMO Introdução: Para a redução dos níveis do paratormônio (PTH) estão disponíveis no mercado brasileiro duas classes de medicamentos: ativadores do receptor da vitamina D (não seletivos e seletivos) e calcimiméticos. Dentre os medicamentos supracitados, o SUS disponibiliza calcitriol oral, paricalcitol e cinacalcete. Objetivos: Desenvolver análise de custo-efetividade (CE) e de impacto orçamentário (IO) do cinacalcete versus paricalcitol para pacientes em diálise com HPTS, na perspectiva do SUS. Metodologia: Foi construído um modelo de árvore de decisão para a análise de CE, que considerou o desfecho paratireoidectomia evitada e um horizonte temporal de 1 ano. Quanto à análise de IO, foram considerados dois cenários, um de demanda aferida e outro de abordagem epidemiológica, baseado nos dados da Sociedade Brasileira de Nefrologia (SBN). Resultados: A análise de CE mostrou que o uso de cinacalcete resulta em economia de R$ 1.394,64 ao ano e efetividade incremental de 0,08, em relação a paratireoidectomia evitada. A razão de CE incremental (RCEI) foi de - R$ 17.653,67 por paratireoidectomia evitada para o cinacalcete, já que se mostrou mais efetivo e mais barato comparado ao paricalcitol. Estimou-se que o IO incremental com a ampliação do uso do cinacalcete no SUS estará entre - R$ 1.640.864,62 e R$ 166.368,50 no primeiro ano, considerando os cenários principal e epidemiológico baseado nos dados da SBN. Já ao final de 5 anos após a ampliação do uso, estimou-se um impacto incremental entre - R$ 10.740.743,86 e - R$ 1.191.339,37; considerando os mesmos cenários. Conclusão: Cinacalcete foi dominante para evitar paratireoidectomias, sendo custo-efetivo.
ABSTRACT Introduction For the reduction of PTH levels, two classes of drugs are available in the Brazilian market: non-selective and selective vitamin D receptor activators and calcimimetics. Among the mentioned drugs, the SUS provides oral calcitriol, paricalcitol and cinacalcet. Objectives: Develop cost-effectiveness (CE) and budgetary impact (BI) analysis of cinacalcet versus paricalcitol for patients on dialysis with SHPT, from the perspective of SUS. Methodology: A decision tree model was constructed for CE analysis, which considered the outcome of avoided parathyroidectomy and a time horizon of 1 year. As for the BI analysis, two scenarios were considered, one of which was measured demand and other epidemiological, based on data from the Brazilian Society of Nephrology (BSN). Results: The CE analysis showed that the use of cinacalcet results in one-off savings of R$1,394.64 per year and an incremental effectiveness of 0.08, in relation to avoided parathyroidectomy. The incremental CE ratio (ICER) was - R$ 17,653.67 per avoided parathyroidectomy for cinacalcet, as it was more effective and cheaper compared to paricalcitol. As for the BI analysis, it was estimated that the incremental BI with the expansion of the use of cinacalcet in the SUS will be between - R$ 1,640,864.62 and R$ 166,368.50 in the first year, considering the main and the epidemiological scenarios. At the end of 5 years after the expansion of use, an BI was estimated between - R$ 10,740,743.86 and - R$ 1,191,339.37; considering the same scenarios. Conclusion: Cinacalcet was dominant to avoid parathyroidectomies, being cost-effective.
3.
Lesão Miocárdica e Prognóstico em Pacientes Hospitalizados com COVID-19 no Brasil: Resultados do Registro Nacional de COVID-19
Facebook Twitter
Facebook Twitter
- Other social networks
- Google+
- StambleUpon
- CiteULike
- Mendeley
- Other networks
- Metrics
Barbosa, Hannah Cardoso
; Martins, Maria Auxiliadora Parreiras
; Jesus, Jordana Cristina de
; Meira, Karina Cardoso
; Passaglia, Luiz Guilherme
; Sacioto, Manuela Furtado
; Bezerra, Adriana Falangola Benjamin
; Schwarzbold, Alexandre Vargas
; Maurílio, Amanda de Oliveira
; Farace, Barbara Lopes
; Silva, Carla Thais Cândida Alves da
; Cimini, Christiane Corrêa Rodrigues
; Silveira, Daniel Vitorio
; Carazai, Daniela do Reis
; Ponce, Daniela
; Costa, Emanuel Victor Alves
; Manenti, Euler Roberto Fernandes
; Cenci, Evelin Paola de Almeida
; Bartolazzi, Frederico
; Madeira, Glícia Cristina de Castro
; Nascimento, Guilherme Fagundes
; Velloso, Isabela Vasconcellos Pires
; Batista, Joanna d’Arc Lyra
; Morais, Júlia Drumond Parreiras de
; Carvalho, Juliana da Silva Nogueira
; Ruschel, Karen Brasil
; Martins, Karina Paula Medeiros Prado
; Zandoná, Liege Barella
; Menezes, Luanna Silva Monteiro
; Kopittke, Luciane
; Castro, Luís César de
; Nasi, Luiz Antônio
; Floriani, Maiara Anschau
; Souza, Maíra Dias
; Carneiro, Marcelo
; Bicalho, Maria Aparecida Camargos
; Lima, Maria Clara Pontello Barbosa
; Godoy, Mariana Frizzo de
; Guimarães-Júnior, Milton Henriques
; Mendes, Paulo Mascarenhas
; Delfino-Pereira, Polianna
; Ribeiro, Raquel Jaqueline Eder
; Finger, Renan Goulart
; Menezes, Rochele Mosmann
; Francisco, Saionara Cristina
; Araújo, Silvia Ferreira
; Oliveira, Talita Fischer
; Oliveira, Thainara Conceição de
; Polanczyk, Carisi Anne
; Marcolino, Milena Soriano
.
Abstract Background Cardiovascular complications of COVID-19 are important aspects of the disease’s pathogenesis and prognosis. Evidence on the prognostic role of troponin and myocardial injury in Latin American hospitalized COVID-19 patients is still scarce. Objectives To evaluate myocardial injury as independent predictor of in-hospital mortality and invasive mechanical ventilation support in hospitalized patients, from the Brazilian COVID-19 Registry. Methods This cohort study is a substudy of the Brazilian COVID-19 Registry, conducted in 31 Brazilian hospitals of 17 cities, March-September 2020. Primary outcomes included in-hospital mortality and invasive mechanical ventilation support. Models for the primary outcomes were estimated by Poisson regression with robust variance, with statistical significance of p<0.05. Results Of 2,925 patients (median age of 60 years [48-71], 57.1% men), 27.3% presented myocardial injury. The proportion of patients with comorbidities was higher among patients with cardiac injury (median 2 [1-2] vs. 1 [0-2]). Patients with myocardial injury had higher median levels of brain natriuretic peptide, lactate dehydrogenase, creatine phosphokinase, N-terminal pro-brain natriuretic peptide, and C-reactive protein than patients without myocardial injury. As independent predictors, C-reactive protein and platelet counts were related to the risk of death, and neutrophils and platelet counts were related to the risk of invasive mechanical ventilation support. Patients with high troponin levels presented a higher risk of death (RR 2.03, 95% CI 1.60-2.58) and invasive mechanical ventilation support (RR 1.87, 95% CI 1.57-2.23), when compared to those with normal troponin levels. Conclusion Cardiac injury was an independent predictor of in-hospital mortality and the need for invasive mechanical ventilation support in hospitalized COVID-19 patients.
Resumo Fundamento As complicações cardiovasculares da COVID-19 são aspectos importantes da patogênese e do prognóstico da doença. Evidências do papel prognóstico da troponina e da lesão miocárdica em pacientes hospitalizados com COVID-19 na América Latina são ainda escassos. Objetivos Avaliar a lesão miocárdica como preditor independente de mortalidade hospitalar e suporte ventilatório mecânico em pacientes hospitalizados, do registro brasileiro de COVID-19. Métodos Este estudo coorte é um subestudo do registro brasileiro de COVID-19, conduzido em 31 hospitais brasileiros de 17 cidades, de março a setembro de 2020. Os desfechos primários incluíram mortalidade hospitalar e suporte ventilatório mecânico invasivo. Os modelos para os desfechos primários foram estimados por regressão de Poisson com variância robusta, com significância estatística de p<0,05. Resultados Dos 2925 pacientes [idade mediana de 60 anos (48-71), 57,1%], 27,3% apresentaram lesão miocárdica. A proporção de pacientes com comorbidades foi maior nos pacientes com lesão miocárdica [mediana 2 (1-2) vs. 1 (0-20)]. Os pacientes com lesão miocárdica apresentaram maiores valores medianos de peptídeo natriurético cerebral, lactato desidrogenase, creatina fosfoquinase, N-terminal do pró-peptídeo natriurético tipo B e proteína C reativa em comparação a pacientes sem lesão miocárdica. Como fatores independentes, proteína C reativa e contagem de plaquetas foram relacionados com o risco de morte, e neutrófilos e contagem de plaquetas foram relacionados ao risco de suporte ventilatório mecânico invasivo. Os pacientes com níveis elevados de troponina apresentaram um maior risco de morte (RR 2,03, IC95% 1,60-2,58) e suporte ventilatório mecânico (RR 1,87;IC95% 1,57-2,23), em comparação àqueles com níveis de troponina normais. Conclusão Lesão cardíaca foi um preditor independente de mortalidade hospitalar e necessidade de suporte ventilatório mecânico em pacientes hospitalizados com COVID-19.
4.
Primary infection of BALB/c mice with a dengue virus type 4 strain leads to kidney injury
Facebook Twitter
Facebook Twitter
- Other social networks
- Google+
- StambleUpon
- CiteULike
- Mendeley
- Other networks
- Metrics
Rasinhas, Arthur da Costa
; Jácome, Fernanda Cunha
; Caldas, Gabriela Cardoso
; de Almeida, Ana Luisa Teixeira
; de Souza, Daniel Dias Coutinho
; dos Santos, João Paulo Rodrigues
; Dias, Helver Gonçalves
; Araujo, Eduarda Lima
; Mohana-Borges, Ronaldo
; Barth, Ortrud Monika
; dos Santos, Flavia Barreto
; Barreto-Vieira, Debora Ferreira
.
BACKGROUND Dengue is a disease caused by dengue virus (DENV-1 through -4). Among the four serotypes, DENV-4 remains the least studied. Acute kidney injury is a potential complication of dengue generally associated with severe dengue infection. OBJECTIVES The goal of this study was to investigate the alterations caused by experimental dengue infection in the kidney of adult BALB/c mice. METHODS In this study, BALB/c mice were infected through the intravenous route with a DENV-4 strain, isolated from a human patient. The kidneys of the mice were procured and subject to histopathological and ultrastructural analysis. FINDINGS The presence of the viral antigen was confirmed through immunohistochemistry. Analysis of tissue sections revealed the presence of inflammatory cell infiltrate throughout the parenchyma. Glomerular enlargement was a common find. Necrosis of tubular cells and haemorrhage were also observed. Analysis of the kidney on a transmission electron microscope allowed a closer look into the necrotic tubular cells, which presented nuclei with condensed chromatin, and loss of cytoplasm. MAIN CONCLUSIONS Even though the kidney is probably not a primary target of dengue infection in mice, the inoculation of the virus in the blood appears to damage the renal tissue through local inflammation.
5.
Artificial neural networks discriminate lettuce seeds with different levels of thermoinhibition
Facebook Twitter
Facebook Twitter
- Other social networks
- Google+
- StambleUpon
- CiteULike
- Mendeley
- Other networks
- Metrics
Catão, Hugo Cesar Rodrigues Moreira
; Cardoso, Daniel Bonifácio Oliveira
; Maciel, Gabriel Mascarenhas
; Gomes, Luiz Antonio Augusto
; Siquieroli, Ana Carolina Silva
; Neves, Flávia de Oliveira Borges Costa
.
Abstract: The thermoinhibition of lettuce seed germination causes important losses for producers, who do not have thermotolerant commercial cultivars. One of the obstacles has been the scarcity of optimizing techniques capable of efficiently discriminating thermotolerant and thermosensitive cultivars. The aim of this work was to evaluate the use of neural networks to discriminate different levels of thermoinhibition in lettuce seeds. Seeds of 18 cultivars were evaluated for thermoinhibition considering the characteristics of the first and last germination count and germination speed index, in seeds subjected to temperatures of 20, 25, 30 and 35 °C. The remaining seeds, which did not germinate, were subjected to the tetrazolium test. Analyses were performed immediately after seed harvesting and repeated after six months of storage. Discriminant analysis was performed and the Kohonen’s Self-Organizing Map (SOM) was created using Artificial Neural Networks (ANNs). Neural networks discriminate lettuce cultivars and organizes them in terms of seed thermoinhibition tolerance through Kohonen’s Self-Organizing Map. Discriminant analysis consistently identifies the Everglades and Luiza genotypes as tolerant to thermoinhibition.
Resumo: A termoinibição causa perdas importantes para os produtores, os quais não dispõem de cultivares comerciais com sementes termotolerantes. Há escassez de técnicas otimizadoras capazes de discriminar cultivares termotolerantes e termosensíveis com eficiência. Objetivou-se avaliar o uso de redes neurais para discriminar diferentes níveis de termoinibição em sementes de alface. Foram avaliadas sementes de 18 cultivares quanto à termoinibição considerando às características de primeira e última contagem de germinação e índice de velocidade de germinação, em sementes submetidas às temperaturas de 20, 25, 30 e 35 °C. As sementes remanescentes, que não germinaram, foram submetidas ao teste de tetrazólio. As análises foram realizadas imediatamente após a colheita das sementes e repetidas após seis meses de armazenamento. Uma análise discriminante e o Mapa Auto-Organizável de Kohonen (SOM) por Redes Neurais Artificiais (RNA’s) foram realizados. As redes neurais discriminam as cultivares de alface e as organiza quanto a tolerância a termoinibição das sementes por meio do Mapa Auto-Organizável de Kohonen. A análise discriminante indentifica de maneira coerente o genótipo Everglades e Luiza como tolerantes a termoinibição.
6.
IMPACTO-MR: um estudo brasileiro de plataforma nacional para avaliar infecções e multirresistência em unidades de terapia intensiva
Facebook Twitter
Facebook Twitter
- Other social networks
- Google+
- StambleUpon
- CiteULike
- Mendeley
- Other networks
- Metrics
Tomazini, Bruno M
; Nassar Jr, Antonio Paulo
; Lisboa, Thiago Costa
; Azevedo, Luciano César Pontes de
; Veiga, Viviane Cordeiro
; Catarino, Daniela Ghidetti Mangas
; Fogazzi, Debora Vacaro
; Arns, Beatriz
; Piastrelli, Filipe Teixeira
; Dietrich, Camila
; Negrelli, Karina Leal
; Jesuíno, Isabella de Andrade
; Reis, Luiz Fernando Lima
; Mattos, Renata Rodrigues de
; Pinheiro, Carla Cristina Gomes
; Luz, Mariane Nascimento
; Spadoni, Clayse Carla da Silva
; Moro, Elisângela Emilene
; Bueno, Flávia Regina
; Sampaio, Camila Santana Justo Cintra
; Silva, Débora Patrício
; Baldassare, Franca Pellison
; Silva, Ana Cecilia Alcantara
; Veiga, Thabata
; Barbante, Leticia
; Lambauer, Marianne
; Campos, Viviane Bezerra
; Santos, Elton
; Santos, Renato Hideo Nakawaga
; Laranjeiras, Ligia Nasi
; Valeis, Nanci
; Santucci, Eliana
; Miranda, Tamiris Abait
; Patrocínio, Ana Cristina Lagoeiro do
; Carvalho, Andréa de
; Sousa, Eduvirgens Maria Couto de
; Sousa, Ancelmo Honorato Ferraz de
; Malheiro, Daniel Tavares
; Bezerra, Isabella Lott
; Rodrigues, Mirian Batista
; Malicia, Julliana Chicuta
; Silva, Sabrina Souza da
; Gimenes, Bruna dos Passos
; Sesin, Guilhermo Prates
; Zavascki, Alexandre Prehn
; Sganzerla, Daniel
; Medeiros, Gregory Saraiva
; Santos, Rosa da Rosa Minho dos
; Silva, Fernanda Kelly Romeiro
; Cheno, Maysa Yukari
; Abrahão, Carolinne Ferreira
; Oliveira Junior, Haliton Alves de
; Rocha, Leonardo Lima
; Nunes Neto, Pedro Aniceto
; Pereira, Valéria Chagas
; Paciência, Luis Eduardo Miranda
; Bueno, Elaine Silva
; Caser, Eliana Bernadete
; Ribeiro, Larissa Zuqui
; Fernandes, Caio Cesar Ferreira
; Garcia, Juliana Mazzei
; Silva, Vanildes de Fátima Fernandes
; Santos, Alisson Junior dos
; Machado, Flávia Ribeiro
; Souza, Maria Aparecida de
; Ferronato, Bianca Ramos
; Urbano, Hugo Corrêa de Andrade
; Moreira, Danielle Conceição Aparecida
; Souza-Dantas, Vicente Cés de
; Duarte, Diego Meireles
; Coelho, Juliana
; Figueiredo, Rodrigo Cruvinel
; Foreque, Fernanda
; Romano, Thiago Gomes
; Cubos, Daniel
; Spirale, Vladimir Miguel
; Nogueira, Roberta Schiavon
; Maia, Israel Silva
; Zandonai, Cassio Luis
; Lovato, Wilson José
; Cerantola, Rodrigo Barbosa
; Toledo, Tatiana Gozzi Pancev
; Tomba, Pablo Oscar
; Almeida, Joyce Ramos de
; Sanches, Luciana Coelho
; Pierini, Leticia
; Cunha, Mariana
; Sousa, Michelle Tereza
; Azevedo, Bruna
; Dal-Pizzol, Felipe
; Damasio, Danusa de Castro
; Bainy, Marina Peres
; Beduhn, Dagoberta Alves Vieira
; Jatobá, Joana D’Arc Vila Nova
; Moura, Maria Tereza Farias de
; Rego, Leila Rezegue de Moraes
; Silva, Adria Vanessa da
; Oliveira, Luana Pontes
; Sodré Filho, Eliene Sá
; Santos, Silvana Soares dos
; Neves, Itallo de Lima
; Leão, Vanessa Cristina de Aquino
; Paes, João Lucidio Lobato
; Silva, Marielle Cristina Mendes
; Oliveira, Cláudio Dornas de
; Santiago, Raquel Caldeira Brant
; Paranhos, Jorge Luiz da Rocha
; Wiermann, Iany Grinezia da Silva
; Pedroso, Durval Ferreira Fonseca
; Sawada, Priscilla Yoshiko
; Prestes, Rejane Martins
; Nascimento, Glícia Cardoso
; Grion, Cintia Magalhães Carvalho
; Carrilho, Claudia Maria Dantas de Maio
; Dantas, Roberta Lacerda Almeida de Miranda
; Silva, Eliane Pereira
; Silva, Antônio Carlos da
; Oliveira, Sheila Mara Bezerra de
; Golin, Nicole Alberti
; Tregnago, Rogerio
; Lima, Valéria Paes
; Silva, Kamilla Grasielle Nunes da
; Boschi, Emerson
; Buffon, Viviane
; Machado, André Sant’Ana
; Capeletti, Leticia
; Foernges, Rafael Botelho
; Carvalho, Andréia Schubert de
; Oliveira Junior, Lúcio Couto de
; Oliveira, Daniela Cunha de
; Silva, Everton Macêdo
; Ribeiro, Julival
; Pereira, Francielle Constantino
; Salgado, Fernanda Borges
; Deutschendorf, Caroline
; Silva, Cristofer Farias da
; Gobatto, Andre Luiz Nunes
; Oliveira, Carolaine Bomfim de
; Dracoulakis, Marianna Deway Andrade
; Alvaia, Natália Oliveira Santos
; Souza, Roberta Machado de
; Araújo, Larissa Liz Cardoso de
; Melo, Rodrigo Morel Vieira de
; Passos, Luiz Carlos Santana
; Vidal, Claudia Fernanda de Lacerda
; Rodrigues, Fernanda Lopes de Albuquerque
; Kurtz, Pedro
; Shinotsuka, Cássia Righy
; Tavares, Maria Brandão
; Santana, Igor das Virgens
; Gavinho, Luciana Macedo da Silva
; Nascimento, Alaís Brito
; Pereira, Adriano J
; Cavalcanti, Alexandre Biasi
.
ABSTRACT Objective: To describe the IMPACTO-MR, a Brazilian nationwide intensive care unit platform study focused on the impact of health care-associated infections due to multidrug-resistant bacteria. Methods: We described the IMPACTO-MR platform, its development, criteria for intensive care unit selection, characterization of core data collection, objectives, and future research projects to be held within the platform. Results: The core data were collected using the Epimed Monitor System® and consisted of demographic data, comorbidity data, functional status, clinical scores, admission diagnosis and secondary diagnoses, laboratory, clinical, and microbiological data, and organ support during intensive care unit stay, among others. From October 2019 to December 2020, 33,983 patients from 51 intensive care units were included in the core database. Conclusion: The IMPACTO-MR platform is a nationwide Brazilian intensive care unit clinical database focused on researching the impact of health care-associated infections due to multidrug-resistant bacteria. This platform provides data for individual intensive care unit development and research and multicenter observational and prospective trials.
RESUMO Objetivo: Descrever o IMPACTO-MR, um estudo brasileiro de plataforma nacional em unidades de terapia intensiva focado no impacto das infecções por bactérias multirresistentes relacionadas à assistência à saúde. Métodos: Descrevemos a plataforma IMPACTO-MR, seu desenvolvimento, critérios para seleção das unidades de terapia intensiva, caracterização da coleta de dados, objetivos e projetos de pesquisa futuros a serem realizados na plataforma. Resultados: Os dados principais foram coletados por meio do Epimed Monitor System® e consistiram em dados demográficos, dados de comorbidades, estado funcional, escores clínicos, diagnóstico de internação e diagnósticos secundários, dados laboratoriais, clínicos e microbiológicos e suporte de órgãos durante a internação na unidade de terapia intensiva, entre outros. De outubro de 2019 a dezembro de 2020, 33.983 pacientes de 51 unidades de terapia intensiva foram incluídos no banco de dados principal. Conclusão: A plataforma IMPACTO-MR é um banco de dados clínico brasileiro de unidades de terapia intensiva focado na pesquisa do impacto das infecções por bactérias multirresistentes relacionadas à assistência à saúde. Essa plataforma fornece dados para o desenvolvimento e pesquisa de unidades de terapia intensiva individuais e ensaios clínicos observacionais e prospectivos multicêntricos.
7.
Art and science: impact of semioccluded vocal tract exercises and choral singing on quality of life in subjects with congenital GH deficiency
Facebook Twitter
Facebook Twitter
- Other social networks
- Google+
- StambleUpon
- CiteULike
- Mendeley
- Other networks
- Metrics
Andrade, Bruna M. R. de
; Valença, Eugenia H. O.
; Salvatori, Roberto
; Oliveira Neto, Luiz A.
; Souza, Anita H. O.
; Oliveira, Alaíde H. A.
; Oliveira, Mario C.P.
; Melo, Enaldo V.
; Carvalho, Susana de
; Sales, Neuza J
; Monteiro, Gisane C.
; Lima, José Marcel de
; Annunziato, Marcos Felipe Harder
; Mannis, Guilherme Daniel Breternitz
; Souza, Lucas E. de A.
; Goes, Yasmin D.
; Carvalho, Thayza S.
; Farias, Celiane de
; Santos, Michela P. dos
; Cardoso, Gabriela P. F.
; Sousa, Carla S. Pereira
; Santana, Julia Rodrigues
; Sales, Ester Almeida
; d’Avila, Jeferson Sampaio
; Aguiar-Oliveira, Manuel H.
.
ABSTRACT Objectives: Currently, not much is known about the interactions between voice and growth hormone (GH). We have described large kindred with isolated GH deficiency (IGHD) due to a GHRH receptor mutation, resulting in severe short stature and high-pitched voice. These IGHD individuals have little interest in GH treatment, as they consider themselves “short long-lived people”, rather than patients. Interestingly, they report normal general quality of life, but they rate their Voice-Related Quality of Life (V-RQOL) as low. Here, we assessed the social and auditory-perceptual impacts of artistic-intervention voice therapy with semioccluded vocal tract exercises (SOVTE) and choral singing, on their voices. Material and methods: Seventeen GH-naïve adult IGHD individuals were enrolled in a single-arm interventional pre-post study with 13 weekly sessions of choir singing over 90 days. Outcome measures were V-RQOL scores, self-assessment of voice, and auditory-perceptual analysis (GRBAS scale, G: grade of the severity of dysphonia; R: roughness; B: breathiness; A: asthenia; and S: strain). Results: Marked improvements in total (p = 0.0001), physical (p = 0.0002), and socioemotional (p = 0.0001) V-RQOL scores and in self-assessment of voice (p = 0.004) were found. The general grades of vocal deviation (p = 0.0001), roughness (p = 0.0001), breathiness (p = 0.0001) and strain (p = 0.0001) exhibited accentuated reductions. Conclusions: Voice therapy with semioccluded vocal tract exercises and choral training improved social impact and perceptual voice assessments in IGHD subjects and markedly improved their voice-related quality of life. This is particularly important in a setting where GH replacement therapy is not widely accepted.
8.
Native legumes and spineless cactus in supplementation of goats grazing in Caatinga rangeland: intake, performance, carcass characteristics, and meat quality
Facebook Twitter
Facebook Twitter
- Other social networks
- Google+
- StambleUpon
- CiteULike
- Mendeley
- Other networks
- Metrics
Oliveira, Liberato Lins de
; Maior Junior, Rinaldo José de Souto
; Cavalcanti, Nathallia de Medeiros
; Cardoso, Daniel Barros
; Morais, Jasiel Santos de
; Magalhães, André Luiz Rodrigues
; Melo, Airon Aparecido Silva de
; Silva, Dulciene Karla de Andrade
.
ABSTRACT. The study evaluated the performance, carcass characteristics, tissue composition, and meat quality of goats raised on pasture in the Caatinga rangeland supplemented with Leucena (Leucaena leucocephala) and Sabiá (Mimosa caesapiniifolia) hays associated or not with spineless cactus (Nopalea cochenillifera), and without supplementation. Thirty male castrated goats, no defined breed, with an average body weight of 15.5 kg ± 0.64 were used, distributed in a randomized block design, according to the initial weight of the animals. The experimental period lasted 105 days. The highest intake of DM, OM and CP occurred in the animals supplemented with Leucena hay associated or not with spineless cactus. The intake of NDF was higher (p <0.05) for animals fed only with Leucena and Sabiá hays. The highest intake of TDN was observed for diets, only grazing, and hays associated with spineless cactus. The daily weight gain for goats fed with Leucena hay and spineless cactus was 68.5% higher (p <0.05) than on grazing alone. Consequently, they obtained the highest (p <0.05) weights and yields of carcasses, shoulder, loin, and leg cuts, conformation and finishing scores, leg muscle index, and % fat in the leg of goats. The meat quality did not differ. The supplementation with Leucena hay associated with spineless cactus improves performance, weights, and yields of the carcass, commercial cuts, leg muscle of goats grazing in the Caatinga rangeland.
9.
Aplicabilidade e potencialidades no uso de ferramentas de Business Intelligence na Atenção Primária em Saúde
Facebook Twitter
Facebook Twitter
- Other social networks
- Google+
- StambleUpon
- CiteULike
- Mendeley
- Other networks
- Metrics
Torres, Douglas Rodrigues
; Cardoso, Gisela Cordeiro Pereira
; Abreu, Dolores Maria Franco de
; Soranz, Daniel Ricardo
; Oliveira, Egléubia Andrade de
.
Resumo As ferramentas de gestão de dados, denominadas Business Intelligence (BI), podem ser importantes para fornecer informações completas e personalizáveis para as demandas da gestão em saúde. O objetivo é apresentar a avaliação da aplicabilidade e potencialidade do uso de uma ferramenta de BI no planejamento das ações de gestão da Atenção Primária em Saúde. Estudo exploratório, de abordagem quantitativa, tendo as dimensões de eficiência e otimização como atributos da qualidade. Seleção de uma Clínica da Família, da cidade do Rio de Janeiro, sendo inseridos no BI dados do território, do cadastro do Programa Bolsa Família e de linhas de cuidado, para explorar as possibilidades de combinação e de geração de indicadores. Neste artigo, apresentamos a Ficha A e a Linha de cuidado da gestante. Como resultados a ampliação de indicadores detalhados em relação à um tabulador comum e otimização na obtenção de listas e do monitoramento por parte das equipes e do gestor. Quanto à eficiência, seu baixo custo e fácil manuseio reduz custos de criação e de profissionais necessários. Conclui-se que a ferramenta viabiliza uma maior organização e planejamento, facilitando a gestão da Clínica da Família, sobretudo no monitoramento dos indicadores e processos avaliativos.
Abstract Data management tools, called Business Intelligence (BI), can be important to provide complete and customizable information for the demands of health management. The objective of the article is to present the evaluation of the applicability and potential of a BI tool in the planning of management actions of Primary Health Care. Exploratory study, with a quantitative approach, using the dimensions of efficiency and optimization as attributes of quality. A Family Clinic was selected in the city of Rio de Janeiro. Data from the territory, from the Bolsa Família Program register and some “Care Lines” were inserted in the BI, in order to explore the possibilities of combining and generating indicators. In this article, we present the use of Form A and the pregnant woman’s Care Line. As a result, greater range of detailed indicators compared to a common tab, and optimization in obtaining lists and perform monitoring tasks by the teams and the manager. Regarding efficiency, its low cost and easy handling reduces the costs of creation and necessary professionals. As a conclusion, the BI tool enables greater organization and planning, facilitating the Family Health Clinic management, mainly for the monitoring of indicators and evaluation processes.
https://doi.org/10.1590/1413-81232021266.03792021
392 downloads
10.
Aplicabilidade e potencialidades no uso de ferramentas de Business Intelligence na Atenção Primária em Saúde
Facebook Twitter
Facebook Twitter
- Other social networks
- Google+
- StambleUpon
- CiteULike
- Mendeley
- Other networks
- Metrics
Torres, Douglas Rodrigues
; Cardoso, Gisela Cordeiro Pereira
; Abreu, Dolores Maria Franco de
; Soranz, Daniel Ricardo
; Oliveira, Egléubia Andrade de
.
Resumo As ferramentas de gestão de dados, denominadas Business Intelligence (BI), podem ser importantes para fornecer informações completas e personalizáveis para as demandas da gestão em saúde. O objetivo é apresentar a avaliação da aplicabilidade e potencialidade do uso de uma ferramenta de BI no planejamento das ações de gestão da Atenção Primária em Saúde. Estudo exploratório, de abordagem quantitativa, tendo as dimensões de eficiência e otimização como atributos da qualidade. Seleção de uma Clínica da Família, da cidade do Rio de Janeiro, sendo inseridos no BI dados do território, do cadastro do Programa Bolsa Família e de linhas de cuidado, para explorar as possibilidades de combinação e de geração de indicadores. Neste artigo, apresentamos a Ficha A e a Linha de cuidado da gestante. Como resultados a ampliação de indicadores detalhados em relação à um tabulador comum e otimização na obtenção de listas e do monitoramento por parte das equipes e do gestor. Quanto à eficiência, seu baixo custo e fácil manuseio reduz custos de criação e de profissionais necessários. Conclui-se que a ferramenta viabiliza uma maior organização e planejamento, facilitando a gestão da Clínica da Família, sobretudo no monitoramento dos indicadores e processos avaliativos.
Abstract Data management tools, called Business Intelligence (BI), can be important to provide complete and customizable information for the demands of health management. The objective of the article is to present the evaluation of the applicability and potential of a BI tool in the planning of management actions of Primary Health Care. Exploratory study, with a quantitative approach, using the dimensions of efficiency and optimization as attributes of quality. A Family Clinic was selected in the city of Rio de Janeiro. Data from the territory, from the Bolsa Família Program register and some “Care Lines” were inserted in the BI, in order to explore the possibilities of combining and generating indicators. In this article, we present the use of Form A and the pregnant woman’s Care Line. As a result, greater range of detailed indicators compared to a common tab, and optimization in obtaining lists and perform monitoring tasks by the teams and the manager. Regarding efficiency, its low cost and easy handling reduces the costs of creation and necessary professionals. As a conclusion, the BI tool enables greater organization and planning, facilitating the Family Health Clinic management, mainly for the monitoring of indicators and evaluation processes.
11.
Determination of the harvest time of sugar apples (Annona squamosa L.) in function of carpel interspace
Facebook Twitter
Facebook Twitter
- Other social networks
- Google+
- StambleUpon
- CiteULike
- Mendeley
- Other networks
- Metrics
Moura, Elias Ariel de
; Chagas, Pollyana Cardoso
; Oliveira, Railin Rodrigues
; Taveira, Daniel Lucas Lima
; Grigio, Maria Luiza
; Araújo, Wellington Farias
.
ABSTRACT. Sugar apples have attracted attention in recent years due to their medicinal and nutritional properties. However, the shelf life of sugar apples is one of the most concerning problems owing to their perishability. This work aimed to determine the ideal harvest time for sugar apple fruits in relation to different classes of carpel interspaces. Therefore, fruits were classified into three stages according to the carpel interspace: stage 1 (0.0 - 2.0 mm); stage 2 (2.1 - 3.0 mm); and stage 3 (3.0 - 4.0 mm). After harvesting, the fruits were evaluated daily in the laboratory regarding their physical and physicochemical aspects until they reached the point of consumption (horticultural maturation). The following variables were evaluated: fruit diameter and length (mm); fruit, peel, pulp, and seed masses (g); color index, including the chromatic attributes L* (luminosity), C* (chroma), and h* (hue angle); bark firmness (N); soluble solids (°Brix); titratable acidity (g citric acid 100 g-1 of pulp-1); pulp yield; and ratio SS/TA. Fruits at stage 3 showed larger diameters, less firmness, and better chromaticity means. Fruits at stages 2 and 3 had eight days of postharvest life. However, fruits at stage 2 took longer for 50% of the fruits to be ready for consumption. The results demonstrate that stages 2 and 3 can be determinants for the harvest time of sugar apples.
https://doi.org/10.4025/actasciagron.v43i1.48732
536 downloads
12.
BRAZILIAN GASTRIC CANCER ASSOCIATION GUIDELINES (PART 2): UPDATE ON TREATMENT
Facebook Twitter
Facebook Twitter
- Other social networks
- Google+
- StambleUpon
- CiteULike
- Mendeley
- Other networks
- Metrics
BARCHI, Leandro Cardoso
; RAMOS, Marcus Fernando Kodama Pertille
; DIAS, André Roncon
; FORONES, Nora Manoukian
; CARVALHO, Marineide Prudêncio de
; CASTRO, Osvaldo Antonio Prado
; KASSAB, Paulo
; COSTA-JÚNIOR, Wilson Luiz da
; WESTON, Antônio Carlos
; ZILBERSTEIN, Bruno
; Ferraz, Álvaro Antônio Bandeira
; ZeideCharruf, Amir
; Brandalise, André
; Silva, André Maciel da
; Alves, Barlon
; Marins, Carlos Augusto Martinez
; Malheiros, Carlos Alberto
; Leite, Celso Vieira
; Bresciani, Claudio José Caldas
; Szor, Daniel
; Mucerino, Donato Roberto
; Wohnrath, Durval R.
; JirjossIlias, Elias
; Martins Filho, Euclides Dias
; PinatelLopasso, Fabio
; Coimbra, Felipe José Fernandez
; Felippe, Fernando E. Cruz
; Tomasisch, Flávio Daniel Saavedra
; Takeda, Flavio Roberto
; Ishak, Geraldo
; Laporte, Gustavo Andreazza
; Silva, Herbeth José Toledo
; Cecconello, Ivan
; Rodrigues, Joaquim José Gama
; Grande, José Carlos Del
; Lourenço, Laércio Gomes
; Motta, Leonardo Milhomem da
; Ferraz, Leonardo Rocha
; Moreira, Luis Fernando
; Lopes, Luis Roberto
; Toneto, Marcelo Garcia
; Mester, Marcelo
; Rodrigues, Marco Antônio Gonçalves
; Franciss, Maurice Youssef
; AdamiAndreollo, Nelson
; Corletta, Oly Campos
; Yagi, Osmar Kenji
; Malafaia, Osvaldo
; Assumpção, Paulo Pimentel
; Savassi-Rocha, Paulo Roberto
; Colleoni Neto, Ramiro
; Oliveira, Rodrigo Jose de
; AissarSallun, Rubens Antonio
; Weschenfelder, Rui
; Oliveira, Saint Clair Vieira de
; Abreu, Thiago Boechat de
; Castria, Tiago Biachi de
; Ribeiro Junior, Ulysses
; Barra, Williams
; Freitas Júnior, Wilson Rodrigues de
.
ABCD. Arquivos Brasileiros de Cirurgia Digestiva (São Paulo)
- Journal Metrics
RESUMO Racional: O II Consenso Brasileiro de Câncer Gástrico da Associação Brasileira de Câncer Gástrico ABCG (Parte 1) foi recentemente publicado. Nesta ocasião inúmeros especialistas que atuam no tratamento desta doença expressaram suas opiniões diante declarações apresentadas. Objetivo: Apresentar as Diretrizes da ABCG (Parte 2) quanto às indicações de tratamento cirúrgico, técnicas operatórias, extensão de ressecção e terapia combinada. Métodos: Para formulação destas diretrizes os autores realizaram extensa e atual revisão referente a cada declaração presente no II Consenso, utilizando as bases Medline/PubMed, Cochrane Library e SciELO, inicialmente com os seguintes descritores: câncer gástrico, gastrectomia, linfadenectomia, terapia combinada. Ainda, cada declaração foi classificada de acordo com o nível de evidência e grau de recomendação. Resultados: Das 43 declarações presentes neste estudo, 11 (25,6%) foram classificadas com nível de evidência A, 20 (46,5%) B e 12 (27,9%) C. Quanto ao grau de recomendação, 18 (41,9%) declarações obtiveram grau de recomendação 1, 14 (32,6%) 2a, 10 (23,3%) 2b e um (2,3%) 3. Conclusão: O complemento das diretrizes aqui presentes possibilita que cirurgiões e oncologistas que atuam no combate ao câncer gástrico possam oferecer o melhor tratamento possível, de acordo com as condições locais disponíveis.
ABSTRACT Background : The II Brazilian Consensus on Gastric Cancer of the Brazilian Gastric Cancer Association BGCA (Part 1) was recently published. On this occasion, countless specialists working in the treatment of this disease expressed their opinion in the face of the statements presented. Aim : To present the BGCA Guidelines (Part 2) regarding indications for surgical treatment, operative techniques, extension of resection and multimodal treatment. Methods: To formulate these guidelines, the authors carried out an extensive and current review regarding each declaration present in the II Consensus, using the Medline/PubMed, Cochrane Library and SciELO databases initially with the following descriptors: gastric cancer, gastrectomy, lymphadenectomy, multimodal treatment. In addition, each statement was classified according to the level of evidence and degree of recommendation. Results : Of the 43 statements present in this study, 11 (25,6%) were classified with level of evidence A, 20 (46,5%) B and 12 (27,9%) C. Regarding the degree of recommendation, 18 (41,9%) statements obtained grade of recommendation 1, 14 (32,6%) 2a, 10 (23,3%) 2b e one (2,3%) 3. Conclusion : The guidelines complement of the guidelines presented here allows surgeons and oncologists who work to combat gastric cancer to offer the best possible treatment, according to the local conditions available.
https://doi.org/10.1590/0102-672020210001e1563
768 downloads
13.
COMVC-19: A Program to protect healthcare workers’ mental health during the COVID-19 Pandemic. What we have learned
Facebook Twitter
Facebook Twitter
- Other social networks
- Google+
- StambleUpon
- CiteULike
- Mendeley
- Other networks
- Metrics
Fukuti, Pedro
; Uchôa, Caroline Louise Mesquita
; Mazzoco, Marina Flaborea
; Cruz, Isabella D'Andrea Garcia da
; Echegaray, Mariana V.F.
; Humes, Eduardo de Castro
; Silveira, Júlia Belizário
; Santi, Talita Di
; Miguel, Euripedes Constantino
; Corchs, Felipe
; Fatori, Daniel
; Campello, Guilherme
; Oliveira, Gabriel M. de
; Argolo, Felipe C.
; Ferreira, Felipe de M.
; Machado, Gustavo
; Argeu, Adriana
; Oliveira, Graça Maria Ramos de
; Serafim, Antônio de Pádua
; Siqueira, Luciana de Lima
; Rossi, Luciane de
; Rios, Izabel Cristina
; Oliveira, Talita Rodrigues de
; Antoniazzi, Leilane C. K.
; Gagliotti, Daniel Augusto Mori
; Abelama Neto, Emílio
; Oliveira Junior, Paulo Novais de
; Correia, Aline Villalobo
; Gonçalves, Luca Schilling
; Tortato, Liana Silva
; Busato, Wagner Machado Moraes
; Guimarães-Fernandes, Flávio
; Alves, Marcos
; Leite Netto, Oswaldo Ferreira
; Schoueri, Patrícia de Campos Lindenberg
; Roque, Márcio de Assis
; Merlin, Silvia Stahl
; Boer, Giovana Cardoso Machado
; Sallet, Paulo Clemente
; Malbergier, André
; Spedo, Mariana Abrahão
; Kamitsuji, Carla Satie
; Faria, Elizabeth de
; Moreira, Moacyr Vergara de Godoy
; Kaufman, Arthur
; Abdo, Carmita
; Scanavino, Marco de Tubino
; Lancman, Selma
; Tavares, Hermano
; Polanczyk, Guilherme
; Brunoni, André R.
; Forlenza, Orestes V.
; Barros-Filho, Tarcísio Eloy Pessoa de
.
OBJECTIVE: In 2020, the COVID-19 pandemic brought a work and stress overload to healthcare workers, increasing their vulnerability to mental health impairments. In response, the authors created the COMVC-19 program. The program offered preventive actions and mental health treatment for the 22,000 workers of The Hospital das Clinicas da Faculdade de Medicina da Universidade de São Paulo (HCFMUSP). This paper aims to describe its implementation and share what we have learned from this experience. METHODS: Workers were able to easily access the program through a 24/7 hotline. Additionally, a mobile phone app that screened for signs and symptoms of emotional distress and offered psychoeducation and/or referral to treatment was made available. Data from both these sources as well as any subsequent psychiatric evaluations were collected. RESULTS: The first 20 weeks of our project revealed that most participants were female, and part of the nursing staff working directly with COVID-19 patients. The most frequently reported symptoms were: anxiety, depression and sleep disturbances. The most common diagnoses were Adjustment, Anxiety, and Mood disorders. CONCLUSIONS: Implementing a mental health program in a multimodal intervention was feasible in a major quaternary public hospital. Our data also suggests that preventive actions should primarily be aimed at anxiety and depression symptoms, with a particular focus on the nursing staff.
14.
Cholestatic syndrome as initial manifestation of pancreatic metastasis of papillary thyroid carcinoma: case report and review
Facebook Twitter
Facebook Twitter
- Other social networks
- Google+
- StambleUpon
- CiteULike
- Mendeley
- Other networks
- Metrics
Tramontin, Mariana Yoshii
; Faria, Paulo Antônio Silvestre de
; Nascimento, Cristina Moreira do
; Barbosa, Cibele de Aquino
; Barros, Maria de Fátima Rei Pereira
; Barros, Aniela Rodrigues Gomes de
; Carvalho, Rafaela Cardoso de
; Castro Neto, Antônio Kneipp Pitta de
; Andrade, Fernanda Accioly de
; Corbo, Rossana
; Vaisman, Fernanda
; Bulzico, Daniel
.
SUMMARY Most papillary thyroid carcinomas (PTC) harbor excellent prognosis. Although rare, distant metastases normally occur in lungs and/or bones. Here we describe a rare case of pancreatic metastasis presenting with rapid onset cholestatic syndrome. A literature review was also performed. A 73-year-old man with a high risk PTC was submitted to total thyroidectomy (TT) followed by radioiodine therapy. After initial therapy, he persisted with progressive rising serum thyroglobulin levels but with no evidence of structural disease. Recently, the patient presented with a rapid onset and progressive cholestatic syndrome. A 4 cm lesion in pancreas was identified, with echoendoscopy fine-needle aspiration biopsy (FNAB) confirming a pancreatic metastasis from PTC. The patient was submitted to a successful pancreaticoduodenectomy. Pancreatic metastases of PTC are rare and few long-term follow-up data are available to guide management. Fourteen cases were former reported, mean age was 65.7 years-old with mean time between PTC and pancreatic metastasis diagnosis of 7.9 years. Nine of them had another distant metastasis, nine were diagnosed by FNAB and just two received sorafenib.
https://doi.org/10.20945/2359-3997000000215
330 downloads
15.
BRAZILIAN GASTRIC CANCER ASSOCIATION GUIDELINES (PART 1): AN UPDATE ON DIAGNOSIS, STAGING, ENDOSCOPIC TREATMENT AND FOLLOW-UP
Facebook Twitter
Facebook Twitter
- Other social networks
- Google+
- StambleUpon
- CiteULike
- Mendeley
- Other networks
- Metrics
BARCHI, Leandro Cardoso
; RAMOS, Marcus Fernando Kodama Pertille
; YAGI, Osmar Kenji
; MUCERINO, Donato Roberto
; BRESCIANI, Claudio José Caldas
; RIBEIRO JÚNIOR, Ulysses
; ANDREOLLO, Nelson Adami
; ASSUMPÇÃO, Paulo Pimentel
; WESTON, Antônio Carlos
; COLLEONI NETO, Ramiro
; ZILBERSTEIN, Bruno
; Ferraz, Álvaro Antônio Bandeira
; Charruf, Amir Zeide
; Dias, André Roncon
; Brandalise, André
; Silva, André Maciel da
; Alves, Barlon
; Malheiros, Carlos Alberto
; Marins, Carlos Augusto Martinez
; Leite, Celso Vieira
; Szor, Daniel
; Wohnrath, Durval R.
; Ilias, Elias Jirjoss
; Martins Filho, Euclides Dias
; Lopasso, Fabio Pinatel
; Coimbra, Felipe José Fernandez
; Felippe, Fernando E. Cruz
; Tomasisch, Flávio Daniel Saavedra
; Takeda, Flavio Roberto
; Ishak, Geraldo
; Laporte, Gustavo Andreazza
; Silva, Herbeth José Toledo
; Cecconello, Ivan
; Rodrigues, Joaquim José Gama
; Grande, José Carlos Del
; Lourenço, Laércio Gomes
; Motta, Leonardo Milhomem da
; Ferraz, Leonardo Rocha
; Moreira, Luis Fernando
; Lopes, Luis Roberto
; Toneto, Marcelo Garcia
; Mester, Marcelo
; Rodrigues, Marco Antônio Gonçalves
; Carvalho, Marineide Prudêncio de
; Franciss, Maurice Youssef
; Forones, Nora Manoukian
; Corletta, Oly Campos
; Castro, Osvaldo Antonio Prado
; Malafaia, Osvaldo
; Kassab, Paulo
; Savassi-Rocha, Paulo Roberto
; Oliveira, Rodrigo Jose de
; Sallun, Rubens Antonio Aissar
; Weschenfelder, Rui
; Oliveira, Saint Clair Vieira de
; Abreu, Thiago Boechat de
; Castria, Tiago Biachi de
; Barra, Williams
; Costa Júnior, Wilson Luiz da
; Freitas Júnior, Wilson Rodrigues de
.
ABCD. Arquivos Brasileiros de Cirurgia Digestiva (São Paulo)
- Journal Metrics
RESUMO Racional: O II Consenso Brasileiro de Câncer Gástrico da Associação Brasileira de Câncer Gástrico (ABCG) foi recentemente publicado. Nesta ocasião, inúmeros especialistas que atuam no tratamento desta doença expressaram sua opinião diante declarações apresentadas. Objetivo: Apresentar as Diretrizes da ABCG (Parte 1) quanto ao diagnóstico, estadiamento, tratamento endoscópico e seguimento dos pacientes com câncer gástrico. Métodos: Para formulação destas Diretrizes os autores realizaram extensa e atual revisão referente a cada declaração presente no II Consenso, utilizando as bases Medline/PubMed, Cochrane Library e SciELO com os seguintes descritores: câncer gástrico, estadiamento, tratamento endoscópico e seguimento. Ainda, cada declaração foi classificada de acordo com o nível de evidência e grau de recomendação. Resultados: Das 24 declarações, duas (8,3%) foram classificadas com nível de evidência A, 11 (45,8%) B e 11 (45,8%) C. Quanto ao grau de recomendação, seis (25%) declarações obtiveram grau de recomendação 1, nove (37,5%) grau 2a, seis (25%) 2b e três (12,5%) 3. Conclusão: As diretrizes aqui presentes têm a finalidade de auxiliar os profissionais que atuam no combate ao câncer gástrico com informações relevantes e atuais, permitindo que sejam aplicadas na prática médica diária.
ABSTRACT Background: The II Brazilian Consensus on Gastric Cancer by the Brazilian Gastric Cancer Association (ABCG) was recently published. On this occasion, several experts in gastric cancer expressed their opinion before the statements presented. Aim: To present the ABCG Guidelines (part 1) regarding the diagnosis, staging, endoscopic treatment and follow-up of gastric cancer patients. Methods: To forge these Guidelines, the authors carried out an extensive and current review regarding each statement present in the II Consensus, using the Medline/PubMed, Cochrane Library and SciELO databases with the following descriptors: gastric cancer, staging, endoscopic treatment and follow-up. In addition, each statement was classified according to the level of evidence and degree of recommendation. Results: Of the 24 statements, two (8.3%) were classified with level of evidence A, 11 (45.8%) with B and 11 (45.8%) with C. As for the degree of recommendation, six (25%) statements obtained grade of recommendation 1, nine (37.5%) recommendation 2a, six (25%) 2b and three (12.5%) grade 3. Conclusion: The guidelines presented here are intended to assist professionals working in the fight against gastric cancer with relevant and current information, granting them to be applied in the daily medical practice.
https://doi.org/10.1590/0102-672020200003e1535
2100 downloads
Showing
itens per page
Page
of 3
Next
Statistics of
Send result
Sem resultados
No documents were found for your search
Glossary and search help
You can enrich your search in a very simple way. Use the search indexes combined with the connectors (AND or OR) and specify more your search.
For example, if you want to search for articles about
cases of dengue in Brasil in 2015, use:ti:dengue and publication_year:2015 and aff_country:Brasil
See below the complete list of search indexes that can be used:
Index code | Element |
---|---|
ti | article title |
au | author |
kw | article keywords |
subject | subject (title words, abstract and keywords) |
ab | abstract |
ta | journal short title (e.g. Cad. Saúde Pública) |
journal_title | journal full title (e.g. Cadernos de Saúde Pública) |
la | publication language code (e.g. pt - Portuguese, es - Spanish) |
type | document type |
pid | publication identifier |
publication_year | publication year of publication |
sponsor | sponsor |
aff_country | country code of the author's affiliation |
aff_institution | author affiliation institution |
volume | article volume |
issue | article issue |
elocation | elocation |
doi | DOI number |
issn | journal ISSN |
in | SciELO colection code (e.g. scl - Brasil, col - Colômbia) |
use_license | article usage license code |