Rapid recognition of the sources of drugs can provide some valuable clues and the basis for determining the nature of the case. A novel recognition method was put forward to identify the sources of heroin drugs rapidly and non-destructively by using a hand-held near infrared (NIR) spectrometer and a multi-layer-extreme learning machine (ML-ELM) algorithm. In contrast to traditional linear discriminant analysis (LDA), support vector machine (SVM) and extreme learning machine (ELM) algorithms, the accuracy, sensitivity and specificity were the highest for the proposed ML-ELM algorithm. The prediction accuracy of the ML-ELM algorithm was 25.33, 20.00, 17.33% higher than that of LDA, SVM and ELM algorithm, respectively, for 4 cases. The ML-ELM models for recognizing the different sources of heroin drugs had the best generalization ability and prediction results. The experimental results indicated that the combination of the hand held NIR technology and ML-ELM algorithm can recognize the different sources of heroin drugs rapidly, accurately, and non-destructively on the spot.

ABSTRACT China's socialized service industry of agricultural machinery emerged as the times required, which resolved the institutional contradiction between small farm households and large-scale agriculture. However, as cross-operation harvesters are still monitored based on phone calls, the monitoring efficiency and real-time performance are relatively poor. To improve the dynamic monitoring accuracy of harvester working areas, we proposed a working progress monitoring method based on harvester traveling trajectory and header status identification. The position and gap bridge angle information of harvesters was synchronously acquired in real-time. The height of the header above ground was calculated to determine whether the harvester was harvesting on a valid trajectory. Finally, the valid trajectory of the harvester was selected for area calculation. Field experiments showed that the header heights at the working and non-working tracing points collected by the system were discretely distributed at intervals of [0m, 0.5m] and (0.5m, 2m), respectively. The working progress monitoring algorithm proposed in this paper effectively improved the monitoring accuracy of harvester working areas. The mean error between the working areas calculated with identifying the header status and the actual cultivated land area in the five test plots was 0.09 hm2, with a mean error rate of 3.10%, 8.59% lower than that without identifying the harvester header status.

Abstract Pristimerin (Pri) was a kind of extraction from natural plant, and it has anti- inflammation effects in previous studies, however, it has been unclear that Pri’s effect in renal fibrosis treatment. The purpose of this research was to evaluate pristimerin (Pri) treatment effects in renal fibrosis and relative mechanisms in vivo study. Using UUO and TGF-β1 to make renal fibrosis rats and HK-2 cell fibrosis model. Evaluating renal tissues pathological and fibrosis by HE and Masson staining; measuring Scr and BUN concentrations of serum, IL-1β, TNF-α, SOD and MDA concentrations by ELISA assay in serum and supernatant. Relative gene expressions were measured by RT-qPCR assay in renal tissues and cells and relative proteins expression by WB assay. Using Double luciferase assay to analysis correlation between miRNA-145-5p and TLR4. NF-κB(p65) nuclear volume were evaluated by cellular immunofluorescence. Scr, BUN, IL-1β, TNF-α and MDA concentrations were significantly increased and SOD concentration was significantly down-regulation (P < 0.001) in Model rats group; miRNA-145-5p gene expression was significantly depressed, TLR4, MyD88 and NF-κB(p65) gene expressions were significantly increased (P < 0.001, respectively); with Pri supplement, the renal pathological, masson region, Scr, BUN, IL-1β, TNF-α, SOD and MDA were significantly improved. In cell experiment, miRNA-145-5p play important role in Pri treatment of renal fibrosis by targeting TLR4. Pri could improve renal fibrosis by via regulation miRNA-145-5p to target TLR4.

ABSTRACT The often widespread and serious Root-Knot Nematode (RKN) disease is an important soil-borne disease affecting tobacco production. This study aimed to understand micro-ecological changes caused by RKN disease and interactions between disease and rhizosphere soil fungal communities. The 18S rRNA gene sequencing was used to study changes in rhizosphere fungal community of tobacco plants having RKN disease. In June 2018, a paired comparison was performed between rhizosphere fungal community structures of healthy tobacco plants and those with RKN disease in Yuxi and Jiuxiang, Yunnan Province, China. Compared with uninfested soil, the OTU abundance, Shannon, ACE and Chao1 indexes of infested soil in the two tobacco areas showed a decreasing trend. Principal Coordinate Analysis showed fungal communities of infested soil and uninfested soil in the two tobacco areas were clustered in different areas, and the community composition was significantly different. Moreover, the dominant fungi community and relative abundance are significantly different at phylum, genus and species levels. More beneficial fungi, such as Penicillium and Aspergillus, were found in soil samples of healthy plants, whereas more pathogenic fungi, such as Phoma and Alternaria, were found in soil samples of diseased plants. In conclusion, changes in fungal community structure and decreases in species diversity and richness were important characteristics of rhizosphere soils from diseased tobacco plants. Disequilibrium in the tobacco rhizosphere micro-ecosystem may allow the development of RKN disease and other more complex diseases.

Abstract Friction stir welding (FSW), a new solid-phase connection method, is considered an excellent welding method for aluminium alloys. Grain orientation, grain boundary structure, and texture types in different regions were characterized by a high-resolution electron backscattered diffraction technology. The results revealed that during the welding process, the coarse grains of the base metal are refined, grains in region 1 (600 μm away from the edge of the keyhole) are arranged in a long strip, and the long axis is approximately parallel to the shear direction. The thermal cycle of the welding process causes some grains to recrystallize, further forming a recrystallization (100) [011] rotating-cube texture. The metal in region 2 (100 μm away from the edge of the keyhole) was severely squeezed by the pin, resulting in an increase in the degree of grain breakage in this region, which were mainly equiaxed grains. Due to the eccentric movement of the pin, the (100) [001]-oriented and (110) [001]-oriented grains alternate on the middle layer, forming a banded structure. Plastic deformation and recrystallization occurred in the base metal, within 383 μm in front of the pin, forming a (110) [001] Goss texture and (100) [001] recrystallized cubic texture.

Abstract Space debris division of PMO is devoted to play an important role in the research of orbital mechanics and the development of space debris observation techniques in China. To support the work, this division builds and operates a large optical network across China. The observational network include two major subsets, large field survey telescopes and precise tracking telescopes. The main objective of the network is to maintain cataloged orbital debris and detect uncatalogued debris. CHES at YaoAn site is the most recent facility, for higher orbits survey. New operational software and data pipeline that aims at detecting unresolved objects has being developed. This paper presents the details of this facility and related activities.

Resumo: O objetivo deste trabalho foi identificar a variação genética de cultivares de milheto (Setaria italica), de três origens ecogeográficas da China, quanto à captação e à utilização de N pelos genótipos no estádio de plântulas, com vistas ao melhoramento genético desta cultura. Plântulas de 79 cultivares de milheto foram fertilizadas com uma solução nutritiva, em substrato de areia, e avaliadas em condições de baixa (LN, 0,2 mmol L-1 N) e alta (HN, 6,0 mmol L-1 N) concentração de N. Observou-se uma grande variação entre as cultivares, entre as origens ecogeográficas, quanto às características biomassa da parte aérea, teor e concentração de N na parte aérea, e eficiência de uso (NUE), captação (NupE) e utilização (NutE) de N, especialmente em condições de HN. As cultivares do Noroeste da China apresentaram as maiores variações de biomassa, teor de N, NUE e NupE. Observou-se, ainda, uma forte correlação positiva entre NUE e NupE, e NUE e NutE, mas não houve correlação entre NupE e NutE. O NupE representou 77,6% da variação total do NUE, e o NutE representou o restante. A captação e a utilização de N apresentam grande variação entre cultivares de milheto no estágio de plântulas, e a variação da captação de N contribui mais do que a da utilização de N para a variação da eficiência de uso de nitrogênio.

Abstract: The objective of this work was to identify the genetic variation of foxtail millet (Setaria italica) cultivars, from three ecogeographic origins in China, regarding the uptake and utilization of N by the genotypes at the seedling stage, aiming at the genetic improvement of this crop. Seedlings of 79 cultivars were fertilized with a nutrient solution, on a sand substrate, and evaluated under low-N (LN, 0.2 mmol L-1) and high-N (HN, 6.0 mmol L-1) concentrations. A large variation was observed between cultivars, among the three ecogeographic regions, for shoot biomass, shoot N content and concentration, and N use efficiency (NUE), uptake efficiency (NupE), and utilization efficiency (NutE), especially under HN conditions. Cultivars of Northwest China showed the highest variation for shoot biomass, N content, NUE, and NupE. A strong positive correlation was observed between NUE and NupE, and NUE and NutE, but there was no correlation between NupE and NutE. NupE accounted for 77.6% of the total variation of NUE, and NutE for the rest. The uptake and utilization of N show a large variation among the foxtail millet cultivars at the seedling stage, and the variation of N uptake contributes more than that of N utilization to the variation of N use efficiency.

ABSTRACT Objectives To provide a meta-analysis of the clinical efficacy and safety of sodium glucose co-transporter 2 inhibitors (SGLT2-i), as a combination treatment with metformin in type 2 diabetes mellitus (T2DM) patients with inadequate glycemic control with metformin alone. Materials and methods We have searched randomized controlled trials (RCTs) in the database: MEDLINE, Embase and Cochrane Collaborative database. We used mean differences (MD) to assess the efficacy of glycemic and other clinical parameters, and risk ratios (RR) to evaluate the adverse events for safety endpoints. The heterogeneity was evaluated by I2. Results Finally 9 studies were included. SGLT2-i plus metformin had higher reduction level in HbA1C [MD = -0.50, 95% CI (-0.62, -0.38), p < 0.00001], FPG [MD = -1.12, 95%CI (-1.38, -0.87), p < 0.00001], body weight [MD = -1.72, 95% CI (-2.05, -1.39), p < 0.00001], SBP [MD = -4.44, 95% CI (-5.45, -3.43), p < 0.00001] and DBP [MD = -1.74, 95% CI (-2.40, -1.07), p < 0.00001] compared with metformin monotherapy. However, SGLT2-i plus metformin group had higher risk of genital infection [RR = 3.98, 95% CI (2.38, 6.67), p < 0.00001]. No significant difference was found in the risk of hypoglycemia, urinary tract infection or volume related adverse events. Conclusions Although the risk of genital infection may increase, SGLT2-i plus metformin may provide an attractive treatment option to those T2DM patients who are unable to achieve glycemic control with metformin alone, based on its effects on glycemic control, reducing body weight and lowering blood pressure.

RESUMEN El complejo máfico de Wuhaolai está ubicado en el margen norte del Cratón del Norte de China (NCC), Mongolia Interior. Para analizar las características mineralógicas, el proceso de evolución del magma y el ajuste tectónico del complejo, analizamos las composiciones geoquímicas de clinopiroxeno y hornblenda utilizando una microsonda de electrones. Los resultados revelaron que el magma parental de este complejo pertenecía a la serie de basalto alcalino intraplaca. La textura normal de zonificación y la relación entre Mg # y FeO, Al2O3, CaO, Na2O, SiO2 y Cr2O3 sugirieron que los clinopiroxenos de piroxenita y gabbro se cristalizaron del mismo magma parental. El contenido similar de CaO de los clinopiroxenos indica que el magma parental del complejo Wuhaolai puede haber sufrido contaminación de la corteza. Además, las características de la hornblenda demostraron que la fuente de magma fue modificada por fluidos derivados de la losa subducida. Sobre la base del valor de Kdcpx (0.23-0.27), la masa fundida en equilibrio con clinopiroxeno exhibió un número de Mg relativamente bajo (43-53), lo que indica que el magma parental se derivó del manto litosférico y se sometió a un fraccionamiento de cristales. Se encontró que la temperatura y la presión de cristalización de gabbro eran más bajas que la de piroxenita, lo que indica que el gabro se formó a una profundidad más baja que la piroxenita. Combinando el diagrama de discriminación del ajuste tectónico del clinopiroxeno con los resultados de estudios previos sobre las últimas intrusiones del Paleozoico cerca del área de investigación, proponemos que el complejo Wuhaolai se forma en un entorno intraplaca. La fuente de magma fue modificada por fluidos derivados de la losa subducida durante la subducción del Océano Paleoasiático (PAO). Después del cierre de la PAO, el magma parental del complejo Wuhaolai se produjo mediante la fusión parcial del manto litosférico enriquecido

ABSTRACT The Wuhaolai mafic complex is located in the north margin of the North China Craton (NCC), Inner Mongolia. To discuss the mineralogical features, magma evolution process, and tectonic setting of the complex, we analyzed the geochemical compositions of clinopyroxene and hornblende using an electron probe. The results revealed that the parental magma of this complex belonged to the intraplate alkaline basalt series. The normal zoning texture and the relation between Mg# and FeO, Al2O3, CaO, Na2O, SiO2 and Cr2O3 suggested that the clinopyroxenes of pyroxenite and gabbro crystallized from the same parental magma. The similar CaO content of clinopyroxenes indicated that the parental magma of the Wuhaolai complex may have suffered crustal contamination. Furthermore, the characteristics of hornblende demonstrated that the magma source was modified by fluids derived from subducted slab. Based on the value of Kdcpx (0.23-0.27), the equilibrium melt with clinopyroxene exhibited a relatively low Mg# (43-53), indicating that the parental magma was derived from the lithospheric mantle and underwent crystal fractionation. The gabbro crystallization temperature and pressure was found to be lower than that of pyroxenite, indicating that gabbro was formed at a lower depth than that of pyroxenite. Combining the tectonic setting discrimination diagram of clinopyroxene with the results of previous studies on the late Paleozoic intrusions near the research area, we proposed that the Wuhaolai complex was formed in an intraplate environment. The magma source was modified by fluids derived from the subducted slab during the subduction of the Paleo-Asian Ocean (PAO). After the PAO closure, the parental magma of the Wuhaolai complex was produced by the partial melting of the enriched lithospheric mantle

Abstract China, origin of mulberry, has rich genetic resources usually. High expense, limited space and wavering environment of usually conservation in vivo poses dangerous situation for mulberry. The concept of core collection could takes priority for conservation of mulberry. In this study, 560 accessions were used with 40 morphological descriptors and stratified sampling strategies for a core collection. The core collection consisted of 28 accessions, accounting for 5% of the whole collection. The core collection included seven accessions belonging to Morus alba, one accession belonging to M. alba var. macrophylla, four accessions belonging to M. atropurprea, one accession belonging to M. nigra, three accessions belonging to M. australis, seven accessions belonging to M. multicaulis, two accessions belonging to M. wittorum and three accessions belonging to M. bombycis. The quality of core collection exceeded the evaluation criteria and could be a prioritized collection for high efficient and long-term conservation for mulberry.

Abstract Purpose: To investigate the long non-coding RNAs (lncRNAs) profile on renal ischemia reperfusion in a mouse model. Methods: Microarray analysis was used to study the expression of misregulated lncRNA in a mouse model of renal ischemia reperfusion(I/R) with long ischemia time. Quantitative real-time PCR (qPCR) was used to verify the expression of selected lncRNAs and mRNAs.The potential functions of the lncRNA was analyzed by bioinformatics tools and databases. Results: Kidney function was impaired in I/R group compared to the normal group. Analysis showed that a total of 2267 lncRNAs and 2341 messenger RNAs (mRNAs) were significantly expressed in I/R group (≥2.0-fold, p < 0.05).The qPCR result showed that lncRNAs and mRNAs expression were consistent with the microarray analysis. The co-expression network profile analysis based on five validated lncRNAs and 203 interacted mRNAs showed it existed a total of 208 nodes and 333 connections. The GO and KEEG pathway analysis results showed that multiple lncRNAs are involved the mechanism of I/R. Conclusion: Multiple lncRNAs are involved in the mechanism of I/R.These analysis results will help us to further understand the mechanism of I/R and promote the new methods targeted at lncRNA to improve I/R injury.

Abstract By using computer program we created a virtual environment to study the possible impacts of sense of agency and sense of ownership on anxiety. The aim of the present study is to investigate whether our setup could achieve the similar effect as traditional rubber hand illusion had, and how sense of self (mainly sense of agency and sense of ownership) affects participants' anxiety. Study 1 the sample consisted of 24 first grade students (12 female, 12 male) who moved a 3D virtual hand in a synchronous or asynchronous situation. Study 2 included 48 first or second grade students (24 female, 24 male) who passed the SCL-90 rating-scale and completed the SCL-90 rating-scale again after they performed a catching/avoiding task. In study 1, all the results only provided evidence for a virtual hand illusion but no other effect. Study 2 showed that asynchronous conditions had higher anxiety scores than synchronous one in terms of modality and sex, different virtual images would lead to participants' different anxious feelings. Sex itself was not a differentiating factor, however, men and women reacted differently in different situations. Results indicated that, in general, sense of agency has more impacts on anxiety level compared with sense of ownership. However, sense of agency seemed to affect male more than female while sense of ownership placed more influence on female than on male. This finding may because the different contribution styles and empathy abilities between men and women.

Resumen Usando un programa de ordenador, creamos un entorno virtual para estudiar los posibles impactos del sentido de agencia y sentido de pertenencia sobre la ansiedad. El objetivo del presente estudio es investigar si nuestra configuración podría lograr el efecto similar al que tenía la ilusión de goma tradicional, y cómo el sentido del yo (principalmente sentido de agencia y sentido de pertenencia) afecta la ansiedad de los participantes. Estudio 1, la muestra consistió en 24 estudiantes de primer grado (12 mujeres, 12 hombres) que movieron una mano virtual en 3D en una situación sincrónica o asincrónica. El estudio 2 incluyó 48 estudiantes de primer o segundo grado (24 mujeres, 24 hombres) que pasaron la escala de calificación SCL-90 y completaron la escala de calificación SCL-90 nuevamente después de realizar una tarea de captura / evitación. En el estudio 1, todos los resultados solo proporcionaron evidencia de una ilusión de mano virtual pero ningún otro efecto. El estudio 2 mostró que las condiciones asincrónicas tenían puntuaciones de ansiedad más altas que las sincrónicas en términos de modalidad y sexo, diferentes imágenes virtuales conducirían a los diferentes sentimientos de ansiedad de los participantes. El sexo en sí mismo no era un factor diferenciador, sin embargo, los hombres y las mujeres reaccionaron de manera diferente en diferentes situaciones. Los resultados indicaron que, en general, el sentido de agencia tiene más impactos en el nivel de ansiedad en comparación con el sentido de pertenencia. Sin embargo, el sentimiento de agencia pareció afectar más a los hombres que a las mujeres, mientras que el sentido de pertenencia ejerció más influencia sobre las mujeres que sobre los hombres. Este hallazgo puede deberse a los diferentes estilos de contribución y habilidades de empatía entre hombres y mujeres.

RESUMO Objetivos: Avaliar os estudos de séries de casos e avaliar quantitativamente os efeitos da trombólise dirigida por cateter (TDC) e comparar a eficácia entre TDC e anticoagulação nos pacientes com trombose venosa profunda aguda das extremidades inferiores (TVP) para tratamento futuro. Métodos: Foram pesquisadas as seguintes bases de dados relevantes: PubMed, Embase, Cochrane, Ovid MEDLINE e Scopus. Os critérios de inclusão foram aplicados para pacientes selecionados com TVP aguda de extremidades inferiores tratados com TDC comparada a TDC com anticoagulação. Nos estudos de série de casos, as estimativas agrupadas de resultados de eficácia para a taxa de permeabilidade, lise completa, retrombose e síndrome pós-trombótica (SPT) foram calculadas em todos os estudos. Em estudos comparando TDC com anticoagulação, foi calculada a razão de chance de resumo (summary odds ratio - OR). Resultados: Vinte e cinco artigos (seis comparando TDC com anticoagulação e 19 séries de casos), incluindo 2.254 pacientes, preencheram os critérios de elegibilidade. Nos estudos da série de casos, os resultados agrupados foram: taxa de permeabilidade 0,87 (IC95%: 0,85-0,89), lise completa 0,58 (IC95%: 0,40-0,75), e retrombose 0,11 (IC95%: 0,06-0,17), SPT 0,10 (IC95%: 0,08-0,12). Seis estudos que compararam os resultados de eficácia entre TDC e anticoagulação mostraram que TDC foi associada à redução da SPT (OR 0,38; IC95%: 0,26-0,55; p<0,0001) e maior taxa de permeabilidade (OR 4,76; IC95%: 2,14-10,56; p<0,0001). Conclusão: Pacientes com TVP aguda de extremidades inferiores que recebem TDC estão associados a uma menor incidência de SPT e maior incidência de taxa de permeabilidade. Em nossa metanálise, TDC é um tratamento eficaz para pacientes com TVP aguda de extremidades inferiores.

ABSTRACT Objectives: To evaluate case series studies that quantitatively assess the effects of catheter-directed thrombolysis (CDT) and compare the efficacy of CDT and anticoagulation in patients with acute lower extremity deep vein thrombosis (DVT). Methods: Relevant databases, including PubMed, Embase, Cochrane, Ovid MEDLINE and Scopus, were searched through January 2017. The inclusion criteria were applied to select patients with acute lower extremity DVT treated with CDT or with anticoagulation. In the case series studies, the pooled estimates of efficacy outcomes for patency rate, complete lysis, rethrombosis and post-thrombotic syndrome (PTS) were calculated across the studies. In studies comparing CDT with anticoagulation, summary odds ratios (ORs) were calculated. Results: Twenty-five articles (six comparing CDT with anticoagulation and 19 case series) including 2254 patients met the eligibility criteria. In the case series studies, the pooled results were a patency rate of 0.87 (95% CI: 0.85-0.89), complete lysis 0.58 (95% CI: 0.40-0.75), rethrombosis 0.11 (95% CI: 0.06-0.17) and PTS 0.10 (95% CI: 0.08-0.12). Six studies comparing the efficacy outcomes of CDT and anticoagulation showed that CDT was associated with a reduction of PTS (OR 0.38, 95%CI 0.26-0.55, p<0.0001) and a higher patency rate (OR 4.76, 95%CI 2.14-10.56, p<0.0001). Conclusion: Acute lower extremity DVT patients receiving CDT were found to have a lower incidence of PTS and a higher incidence of patency rate. In our meta-analysis, CDT is shown to be an effective treatment for acute lower extremity DVT patients.

RESUMEN Objetivos: Evaluar estudios de series de casos y evaluar cuantitativamente los efectos de la trombólisis dirigida por catéter (TDC) y comparar la eficacia entre la TDC y anticoagulación en pacientes con trombosis venosa profunda (TVP) aguda de las extremidades inferiores para el tratamiento futuro. Métodos: Se realizaron búsquedas en bases de datos relevantes, incluyendo PubMed, Embase, Cochrane, Ovid MEDLINE y Scopus hasta enero de 2017. Los criterios de inclusión se aplicaron a pacientes seleccionados con TVP aguda de extremidad inferior tratados con TDC o comparados con TDC y anticoagulación. En estudios de series de casos, las estimaciones agrupadas de los resultados de eficacia para la tasa de patencia, la lisis completa, la retrombosis y el síndrome postrombótico (SPT) se calcularon a través de los estudios. En estudios que compararon la TDC con la anticoagulación, se calculó el resumen de las razónes de posibilidades (RP). Resultados: 25 artículos (seis que comparan TDC con anticoagulación y 19 series de casos) que incluyeron 2254 pacientes qienes cumplieron los criterios de elegibilidad. En los estudios de series de casos, los resultados agrupados fueron: tasa de patencia 0,87 (IC 95%: 0,85; 0,89), lisis completa 0,58 (IC 95%: 0,40; 0,75), retrombosis 0,11 (IC 95%: 0,06; 17,0), SPT 0,10 (IC 95%: 0,08; 0,12). Seis estudios que compararon los resultados de eficacia entre la TDC y anticoagulación mostraron que la TDC se asoció con una reducción de SPT (RP 0,38; IC 95%: 0,26; 0,55; p<0,0001) y una mayor tasa de patencia (RP 4,76; IC 95%: 2,14; 10,56; p<0,0001). Conclusión: Los pacientes con TVP aguda de extremidad inferior que reciben TDC se asocian con una menor incidencia de SPT y una mayor incidencia de tasa de patencia. En nuestro metanálisis, la TDC es un tratamiento efectivo para pacientes con TVP aguda de extremidad inferior.

ABSTRACT Objectives: To evaluate case series studies that quantitatively assess the effects of catheter-directed thrombolysis (CDT) and compare the efficacy of CDT and anticoagulation in patients with acute lower extremity deep vein thrombosis (DVT). Methods: Relevant databases, including PubMed, Embase, Cochrane, Ovid MEDLINE and Scopus, were searched through January 2017. The inclusion criteria were applied to select patients with acute lower extremity DVT treated with CDT or with anticoagulation. In the case series studies, the pooled estimates of efficacy outcomes for patency rate, complete lysis, rethrombosis and post-thrombotic syndrome (PTS) were calculated across the studies. In studies comparing CDT with anticoagulation, summary odds ratios (ORs) were calculated. Results: Twenty-five articles (six comparing CDT with anticoagulation and 19 case series) including 2254 patients met the eligibility criteria. In the case series studies, the pooled results were a patency rate of 0.87 (95% CI: 0.85-0.89), complete lysis 0.58 (95% CI: 0.40-0.75), rethrombosis 0.11 (95% CI: 0.06-0.17) and PTS 0.10 (95% CI: 0.08-0.12). Six studies comparing the efficacy outcomes of CDT and anticoagulation showed that CDT was associated with a reduction of PTS (OR 0.38, 95%CI 0.26-0.55, p<0.0001) and a higher patency rate (OR 4.76, 95%CI 2.14-10.56, p<0.0001). Conclusion: Acute lower extremity DVT patients receiving CDT were found to have a lower incidence of PTS and a higher incidence of patency rate. In our meta-analysis, CDT is shown to be an effective treatment for acute lower extremity DVT patients.

RESUMEN Objetivos: Evaluar estudios de series de casos y evaluar cuantitativamente los efectos de la trombólisis dirigida por catéter (TDC) y comparar la eficacia entre la TDC y anticoagulación en pacientes con trombosis venosa profunda (TVP) aguda de las extremidades inferiores para el tratamiento futuro. Métodos: Se realizaron búsquedas en bases de datos relevantes, incluyendo PubMed, Embase, Cochrane, Ovid MEDLINE y Scopus hasta enero de 2017. Los criterios de inclusión se aplicaron a pacientes seleccionados con TVP aguda de extremidad inferior tratados con TDC o comparados con TDC y anticoagulación. En estudios de series de casos, las estimaciones agrupadas de los resultados de eficacia para la tasa de patencia, la lisis completa, la retrombosis y el síndrome postrombótico (SPT) se calcularon a través de los estudios. En estudios que compararon la TDC con la anticoagulación, se calculó el resumen de las razónes de posibilidades (RP). Resultados: 25 artículos (seis que comparan TDC con anticoagulación y 19 series de casos) que incluyeron 2254 pacientes qienes cumplieron los criterios de elegibilidad. En los estudios de series de casos, los resultados agrupados fueron: tasa de patencia 0,87 (IC 95%: 0,85; 0,89), lisis completa 0,58 (IC 95%: 0,40; 0,75), retrombosis 0,11 (IC 95%: 0,06; 17,0), SPT 0,10 (IC 95%: 0,08; 0,12). Seis estudios que compararon los resultados de eficacia entre la TDC y anticoagulación mostraron que la TDC se asoció con una reducción de SPT (RP 0,38; IC 95%: 0,26; 0,55; p<0,0001) y una mayor tasa de patencia (RP 4,76; IC 95%: 2,14; 10,56; p<0,0001). Conclusión: Los pacientes con TVP aguda de extremidad inferior que reciben TDC se asocian con una menor incidencia de SPT y una mayor incidencia de tasa de patencia. En nuestro metanálisis, la TDC es un tratamiento efectivo para pacientes con TVP aguda de extremidad inferior.

RESUMO Objetivos: Avaliar os estudos de séries de casos e avaliar quantitativamente os efeitos da trombólise dirigida por cateter (TDC) e comparar a eficácia entre TDC e anticoagulação nos pacientes com trombose venosa profunda aguda das extremidades inferiores (TVP) para tratamento futuro. Métodos: Foram pesquisadas as seguintes bases de dados relevantes: PubMed, Embase, Cochrane, Ovid MEDLINE e Scopus. Os critérios de inclusão foram aplicados para pacientes selecionados com TVP aguda de extremidades inferiores tratados com TDC comparada a TDC com anticoagulação. Nos estudos de série de casos, as estimativas agrupadas de resultados de eficácia para a taxa de permeabilidade, lise completa, retrombose e síndrome pós-trombótica (SPT) foram calculadas em todos os estudos. Em estudos comparando TDC com anticoagulação, foi calculada a razão de chance de resumo (summary odds ratio - OR). Resultados: Vinte e cinco artigos (seis comparando TDC com anticoagulação e 19 séries de casos), incluindo 2.254 pacientes, preencheram os critérios de elegibilidade. Nos estudos da série de casos, os resultados agrupados foram: taxa de permeabilidade 0,87 (IC95%: 0,85-0,89), lise completa 0,58 (IC95%: 0,40-0,75), e retrombose 0,11 (IC95%: 0,06-0,17), SPT 0,10 (IC95%: 0,08-0,12). Seis estudos que compararam os resultados de eficácia entre TDC e anticoagulação mostraram que TDC foi associada à redução da SPT (OR 0,38; IC95%: 0,26-0,55; p<0,0001) e maior taxa de permeabilidade (OR 4,76; IC95%: 2,14-10,56; p<0,0001). Conclusão: Pacientes com TVP aguda de extremidades inferiores que recebem TDC estão associados a uma menor incidência de SPT e maior incidência de taxa de permeabilidade. Em nossa metanálise, TDC é um tratamento eficaz para pacientes com TVP aguda de extremidades inferiores.

Abstract: WeChat payment has recently become a popular mobile payment service in China by bundling with WeChat, the most popular social network service in China. It is interesting to investigate the reasons for its popularity. In this research, we applied the technology acceptance model to predict its acceptability and to identify variables attributing to its popularity. In addition to the primary explanatory variables, i.e., Perceived Ease of Use and Perceived Usefulness, the proposed framework is further extended to include the constructs of Social Interaction, Trust, Perceived Enjoyment and Use Context. The results indicated that the proposed model is able to explain the variance in a user’s intention to use WeChat payment service. We hope this study can provide insights into understanding the adoption behaviour of socially aware mobile payment services.