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Resumo A inquestionável precariedade do sistema penitenciário brasileiro, discutida na ADPF 347/2015, levou o Supremo Tribunal Federal, no julgamento da medida cautelar, a declarar o estado de coisas inconstitucional, inaugurando-se, assim, um debate de relevo perante a referida Corte, que impõe a discussão, a reflexão e, possivelmente, a revisão de conceitos e teorias já arraigados, como a questão da separação de poderes e da legitimidade democrática do Poder Judiciário, especialmente no tocante à concepção, implementação e monitoramento de políticas públicas, o que refrata, diretamente, na relação da judicial review ante o sistema democrático. Considerando a envergadura do debate e das alternativas propostas para a resolução de problemas estruturais, é que se desenvolveu o presente estudo com o propósito de analisar a viabilidade da prática do constitucionalismo dialógico e a celebração do compromisso significativo, uma vez reconhecido o estado de coisas inconstitucional. Nessa linha, coloca-se a necessidade de construção de um debate aberto entre as instâncias eletivas com a Suprema Corte como forma de se buscar a construção de consensos capazes de superar desafios comuns, com respeito à ordem constitucional. Para tanto, realizou-se pesquisa bibliográfico-documental, revelando-se esta como uma pesquisa pura, qualitativa e exploratória.

Abstract The unquestionable precariousness of the Brazilian penitentiary system, discussed in ADPF 347/2015, led the Federal Supreme Court, in the judgment of the injuction, to declare the unconstitutional state of affairs, thus inaugurating a relevant discuss in the Court, which calls for discussion, reflection and, possibly, a review of concepts and theories already established, such as the question of the powers separation and the democratic legitimacy of the Judiciary, especially with regard to the conception, implementation and monitoring of public policies which refracts, directly, in the relation of judicial review on the democratic system. Considering the scope of the debate and the alternatives proposed for the resolution of structural problems is developed the present study, with the purpose of verifying the feasibility of the practice of dialogical constitutionalism and the celebration of the meaningful engagement, once recognized the unconstitutional state of affairs. In this sense, it is necessary to build an open debate between the elective bodies and the Supreme Court, as a way to the construction of consensus able to overcome common challenges, related to the constitutional order. For this purpose, a bibliographic-documentary research was conducted, revealing itself as a pure, qualitative and exploratory research.

https://doi.org/10.5380/rinc.v8i3.72953

Cannabinoids in Neurology - Position paper from Scientific Departments from Brazilian Academy of Neurology
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BRUCKI, Sonia Maria Dozzi

; ADONI, Tarso

; ALMEIDA, Carlos Mauricio Oliveira

; ANDRADE, Daniel Ciampi de

; ANGHINAH, Renato

; BARBOSA, Luciana Mendonça

; BAZAN, Rodrigo

; CARVALHO, Alzira Alves de Siqueira

; CARVALHO, William

; CHRISTO, Paulo Pereira

; COLETTA, Marcus Della

; CONFORTO, Adriana Bastos

; CORREA-NETO, Ylmar

; ENGELHARDT, Eliasz

; FRANÇA JUNIOR, Marcondes Cavalcante

; FRANCO, Clelia

; VON GLEHN, Felipe

; GOMES, Helio Rodrigues

; HOULY, Caroline Gomes de Barros

; KAUP, Alexandre Ottoni

; KOWACS, Fernando

; KANASHIRO, Aline

; LOPES, Victor Gonçalves

; MAIA, Débora

; MANREZA, Maria

; MARTINEZ, Alberto Rolim Muro

; MARTINEZ, Sandra Cristina Gonçalves

; NADER, Saulo Nardy

; NEVES, Luciana de Oliveira

; OKAMOTO, Ivan Hideyo

; OLIVEIRA, Rogério Adas Ayres de

; PEIXOTO, Fabiano de Melo

; PEREIRA, Cristiana Borges

; SABA, Roberta Arb

; SAMPAIO, Leticia Pereira de Brito

; SCHILLING, Lucas Porcello

; SILVA, Marcus Tulius Teixeira

; SILVA, Emanuelle Roberta

; SMID, Jerusa

; SOARES, Cristiane Nascimento

; SOBREIRA-NETO, Manoel

; SOUSA, Nise Alessandra de Carvalho

; SOUZA, Leonardo Cruz de

; TEIVE, Hélio Afonso Ghizoni

; TERRA, Vera Cristina

; VALE, Matheus

; VIEIRA, Vitor Mendes Grise

; ZANOTELI, Edmar

; PRADO, Gilmar

Arquivos de Neuro-Psiquiatria

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apr 2021, Volume 79 N. 4 Pages 354 - 369

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Os canabinoides compreendem os endocanabinoides, fitocanabinoides e os canabinoides sintéticos e desempenham ações no sistema nervoso central e periférico. Uma quantidade enorme de publicações tem sido lançada nos últimos anos, embora a cannabis seja conhecida por milênios. Os Departamentos Científicos da Academia Brasileira de Neurologia descreveram as evidências do uso médico em suas áreas. A literatura está em constantes mudanças e possíveis novas evidências podem surgir nos próximos dias ou meses. A prescrição dessas substâncias deve ser discutida com os pacientes e suas famílias, com conhecimento sobre eventos adversos e sua eficácia.

ABSTRACT Cannabinoids comprehend endocannabinoids, phytocannabinoids, and synthetic cannabinoids, with actions both in the central and peripherical nervous systems. A considerable amount of publications have been made in recent years, although cannabis has been known for over a thousand years. Scientific Departments from the Brazilian Academy of Neurology described evidence for medical use in their areas. Literature is constantly changing, and possible new evidence can emerge in the next days or months. Prescription of these substances must be discussed with patients and their families, with knowledge about adverse events and their efficacy.

https://doi.org/10.1590/0004-282x-anp-2020-0432 1049 downloads

STUDY OF THE INFLUENCE OF WOOD PROPERTIES ON THE CHARCOAL PRODUCTION: APPLYING THE RANDOM FOREST ALGORITHM
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Pereira, Kaléo Dias

; Carneiro, Antônio Policarpo Souza

; Santos, Gerson Rodrigues dos

; Carneiro, Angélica de Cassia Oliveira

; Leite, Hélio Garcia

; Borges, Felipe Pedersoli

Revista Árvore

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2021, Volume 45 elocation e4502

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO O entendimento das relações entre as propriedades da madeira e do carvão vegetal possibilita a melhoria da produção de carvão. Sendo assim, neste estudo utilizou-se o algoritmo random forest para análise da influência de propriedades da madeira de eucalipto sobre a qualidade do carvão vegetal, bem como avaliou-se a acurácia dos valores preditos em relação às estimativas do support vector regression e da regressão linear múltipla. Foram mensuradas seis propriedades da madeira e seis do carvão do híbrido Eucalyptus grandis x Eucalyptus urophylla e de doze clones de Corymbia torelliana x Corymbia critriodora com sete anos de idade. Nas análises, foi utilizado a medida de redução média da impureza do nó (soma de quadrados residual) do random forest e a correlação de cópulas para avaliar a relação entre propriedades da madeira e do carvão. O random forest foi comparado ao support vector regression e à regressão linear múltipla por meio do coeficiente de determinação, correlação linear entre valores observados e preditos, erro médio absoluto e raiz quadrada do erro quadrático médio. A acurácia do random forest foi maior que a do support vector regression e da regressão linear múltipla, principalmente em termos de coeficiente de determinação e correlação linear entre valores observados e preditos. O rendimento e qualidade do carvão vegetal dos clones foram influenciados, principalmente, pelo teor de holocelulose, relação cerne/alburno e densidade básica da madeira. A densidade relativa aparente do carvão foi a variável em que o random forest atingiu o melhor nível de explicação da variabilidade em função das propriedades da madeira, enquanto para o teor de carbono fixo o algoritmo forneceu predições com menor erro.

ABSTRACT The understanding of the relationship between the properties of wood and charcoal makes it possible to improve the production of charcoal. Therefore, the random forest algorithm was used in this study to analyze the influence of eucalyptus wood properties on the quality of charcoal as well as the accuracy of the predicted values concerning the results estimated by support vector regression and multiple linear regression. Six properties of wood and six properties of charcoal obtained from the hybrid Eucalyptus grandis x Eucalyptus urophylla and from twelve clones of Corymbia torelliana x Corymbia critriodora at the age of seven were measured. In the analysis, the measure of mean decrease in node impurity (residual sum of squares) calculated with the random forest and the copula correlation was used to evaluate the relationship between properties of wood and charcoal. The random forest was compared to the support vector regression and multiple linear regression through the coefficient of determination, linear correlation between observed and predicted values, mean absolute error and root mean squared error. The accuracy of the random forest was greater than that obtained with the support vector regression and multiple linear regression, mainly in terms of the coefficient of determination and the linear correlation between observed and predicted values. The yield and quality of the charcoal produced from clones were mainly influenced by the holocellulose content, heartwood/sapwood ratio, and basic wood density. The apparent relative density of charcoal was the variable in which the random forest algorithm reached the best level of explanation of the variability as a function of the properties of wood, while the minor error was observed for the fixed carbon content.

https://doi.org/10.1590/1806-908820210000002 733 downloads

Acute Disseminated Encephalomyelitis in COVID-19: presentation of two cases and review of the literature
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Lopes, Cesar Castello Branco

; Brucki, Sonia Maria Dozzi

; Passos Neto, Carlos Eduardo Borges

; Corazza, Luiza Alves

; Baima, José Pedro Soares

; Fiorentino, Matheus Dalben

; Tatsch, João Fellipe Santos

; Martin, Maria da Graça Morais

; Lucato, Leandro Tavares

; Gomes, Hélio Rodrigues

; Rocha, Maria Sheila Guimarães

; Fortini, Ida

; Nitrini, Ricardo

; Castro, Luiz H.

Arquivos de Neuro-Psiquiatria

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dec 2020, Volume 78 N. 12 Pages 805 - 810

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Introdução: As manifestações neurológicas causadas pela COVID-19 ainda não estão completamente elucidadas. O comprometimento neurológico pode decorrer de um efeito viral direto em neurônios ou em células gliais, a efeito imunomediado em resposta à infecção viral, ou de um efeito secundário a estados de hipercoagulabilidade e danos endoteliais, assim como decorrente de complicações sistêmicas graves relacionadas a cuidados intensivos prolongados na unidade de terapia intensiva. Objetivo: Descrever dois pacientes com recuperação tardia do nível de consciência após a retirada da sedação associados à infecção grave pelo SARS-CoV-2, que apresentaram lesões multifocais de substância branca, compatíveis com o diagnóstico de encefalomielite disseminada aguda. Métodos: Estudo observacional, com relato de dois casos de infecção grave pela COVID-19, em dois hospitais terciários na cidade de São Paulo, Brasil. Resultados: Os pacientes foram submetidos à investigação sistêmica e neurológica para avaliação de estado alterado de consciência após retirada de sedação. A ressonância magnética de crânio evidenciou lesões multifocais no centro semioval, sugestivos de processo inflamatório desmielinizante. Análise liquórica evidenciou PCR negativo para SARS-CoV-2 em ambos os casos. Conclusão: Lesões multifocais de substância branca podem ocorrer em pacientes com COVID-19, possivelmente associadas a estados alterados de consciência. Estudos adicionais são necessários para determinar o processo fisiopatológico da infecção viral e dos estados inflamatórios e imunomediados na gênese das manifestações neurológicas causadas pela COVID-19.

ABSTRACT Background: Neurological manifestations of COVID-19 are still incompletely understood. Neurological manifestations may be due to direct viral effect on neurons and glial cells, to an immune-mediated response to the virus, or to a hypercoagulable state and associated endothelial damage, as well as to severe systemic disease with prolonged intensive care unit stay. Objective: To describe two patients with severe SARS-CoV-2 infection and delayed recovery of consciousness after sedation withdrawal, in whom MRI disclosed multifocal white matter brain lesions, compatible with the diagnosis of acute disseminated encephalomyelitis. Methods: Observational report of two cases of severe COVID-19 infection in patients from two tertiary hospitals in São Paulo, Brazil. Results: These patients underwent neurologic and systemic evaluation for delayed awakening after sedation withdrawal. MRI displayed multifocal centrum semiovale lesions, suggestive of demyelinating inflammation. Cerebrospinal fluid (CSF) polymerase chain reaction (PCR) for SARS-CoV-2 was negative in both cases. Conclusion: A recurrent pattern of multifocal white matter lesions can occur in COVID-19 patients, possibly associated with delayed awakening. Additional studies are necessary to elucidate the role of the viral infection and of inflammatory and immune-mediated associated changes in neurological manifestations of COVID-19.

https://doi.org/10.1590/0004-282x20200186 2670 downloads

Neurological consultations and diagnoses in a large, dedicated COVID-19 university hospital
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STUDART-NETO, Adalberto

; GUEDES, Bruno Fukelmann

; TUMA, Raphael de Luca e

; CAMELO FILHO, Antonio Edvan

; KUBOTA, Gabriel Taricani

; IEPSEN, Bruno Diógenes

; MOREIRA, Gabriela Pantaleão

; RODRIGUES, Júlia Chartouni

; FERRARI, Maíra Medeiros Honorato

; CARRA, Rafael Bernhart

; SPERA, Raphael Ribeiro

; OKU, Mariana Hiromi Manoel

; TERRIM, Sara

; LOPES, Cesar Castello Branco

; PASSOS NETO, Carlos Eduardo Borges

; FIORENTINO, Matheus Dalben

; DE SOUZA, Julia Carvalhinho Carlos

; BAIMA, José Pedro Soares

; DA SILVA, Tomás Fraga Ferreira

; MORENO, Cristiane Araujo Martins

; SILVA, Andre Macedo Serafim

; HEISE, Carlos Otto

; MENDONÇA, Rodrigo Holanda

; FORTINI, Ida

; SMID, Jerusa

; ADONI, Tarso

; GONÇALVES, Marcia Rubia Rodrigues

; PEREIRA, Samira Luisa Apóstolos

; PINTO, Lecio Figueira

; GOMES, Helio Rodrigues

; ZANOTELI, Edmar

; BRUCKI, Sonia Maria Dozzi

; CONFORTO, Adriana Bastos

; CASTRO, Luiz Henrique Martins

; NITRINI, Ricardo

Arquivos de Neuro-Psiquiatria

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aug 2020, Volume 78 N. 8 Pages 494 - 500

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Introdução: Mais de um terço dos pacientes com COVID-19 apresentam sintomas neurológicos que variam de anosmia a AVC e encefalopatia. Além disso, doenças neurológicas prévias podem exigir tratamento especial e estar associadas a piores desfechos. Não obstante, o papel dos neurologistas na COVID-19 é provavelmente pouco reconhecido. Objetivo: O objetivo deste estudo foi relatar os motivos para solicitar consultas neurológicas por clínicos e intensivistas em um hospital dedicado à COVID-19. Métodos: Estudo retrospectivo realizado no Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, Brasil, um centro dedicado à COVID-19 com 900 leitos (incluindo 300 leitos para unidades de terapia intensiva). O diagnóstico de COVID-19 foi confirmado por SARS-CoV-2-RT-PCR em swabs nasais. Todas as interconsultas de neurologia hospitalar entre 23 de março e 23 de maio de 2020 foram analisadas. Os neurologistas realizaram o exame neurológico, avaliaram todos os dados disponíveis para diagnosticar a patologia neurológica e solicitaram exames adicionais conforme necessidade. Diagnósticos difíceis foram estabelecidos em reuniões de consenso. Após o diagnóstico, os neurologistas participaram da condução dos casos. Resultados: Foram solicitadas consultas neurológicas para 89 de 1.208 (7,4%) em pacientes internados por COVID-19 durante o período. Os principais diagnósticos neurológicos incluíram: encefalopatia (44,4%), acidente vascular cerebral (16,7%), doenças neurológicas prévias (9,0%), crises epilépticas (9,0%), transtornos neuromusculares (5,6%), outras lesões encefálicas agudas (3,4%) e outros sintomas leves inespecíficos (11,2%). Conclusões: A maioria das consultas neurológicas em um hospital dedicado à COVID-19 foi solicitada para condições graves que poderiam afetar o desfecho clínico. Os médicos na linha de frente devem ser capazes de reconhecer sintomas neurológicos. Os neurologistas são membros importantes da equipe médica no atendimento hospitalar à COVID-19.

ABSTRACT Background: More than one-third of COVID-19 patients present neurological symptoms ranging from anosmia to stroke and encephalopathy. Furthermore, pre-existing neurological conditions may require special treatment and may be associated with worse outcomes. Notwithstanding, the role of neurologists in COVID-19 is probably underrecognized. Objective: The aim of this study was to report the reasons for requesting neurological consultations by internists and intensivists in a COVID-19-dedicated hospital. Methods: This retrospective study was carried out at Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, Brazil, a 900-bed COVID-19 dedicated center (including 300 intensive care unit beds). COVID-19 diagnosis was confirmed by SARS-CoV-2-RT-PCR in nasal swabs. All inpatient neurology consultations between March 23rd and May 23rd, 2020 were analyzed. Neurologists performed the neurological exam, assessed all available data to diagnose the neurological condition, and requested additional tests deemed necessary. Difficult diagnoses were established in consensus meetings. After diagnosis, neurologists were involved in the treatment. Results: Neurological consultations were requested for 89 out of 1,208 (7.4%) inpatient COVID admissions during that period. Main neurological diagnoses included: encephalopathy (44.4%), stroke (16.7%), previous neurological diseases (9.0%), seizures (9.0%), neuromuscular disorders (5.6%), other acute brain lesions (3.4%), and other mild nonspecific symptoms (11.2%). Conclusions: Most neurological consultations in a COVID-19-dedicated hospital were requested for severe conditions that could have an impact on the outcome. First-line doctors should be able to recognize neurological symptoms; neurologists are important members of the medical team in COVID-19 hospital care.

https://doi.org/10.1590/0004-282x20200089 2651 downloads

[SciELO Preprints] - Neurological consultations and diagnoses in a large, dedicated COVID-19 university hospital
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Studart-Neto, Adalberto Guedes, Bruno Fukelmann Tuma, Raphael De Luca E Camelo Filho, Antonio Edvan Kubota, Gabriel Taricani Iepsen, Bruno Diógenes Moreira, Gabriela Pantaleão Rodrigues, Júlia Chartouni Ferrari, Maíra Medeiros Honorato Carra, Rafael Bernhard Spera, Raphael Ribeiro Oku, Mariana Hiromi Manoel Terrim, Sara Lopes, Cesar Castello Branco Passos Neto, Carlos Eduardo Borges Dalben, Matheus De Souza, Julia Carvalhinho Carlos Baima, José Pedro Soares Da Silva, Tomás Fraga Ferreira Moreno, Cristiane Araujo Martins Silva, Andre Macedo Serafim Heise, Carlos Otto Mendonça, Rodrigo Holanda Fortini, Ida Smid, Jerusa Adoni, Tarso Gonçalves, Marcia Rubia Rodrigues Pereira, Samira Luisa Apóstolos Pinto, Lecio Figueira Gomes, Helio Rodrigues Zanotelli, Edmar Brucki, Sonia Maria Dozzi Conforto, Adriana Bastos Castro, Luiz Henrique Martins Nitrini, Ricardo

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Publication date: 2020-07-16

Abstract: En Pt

Background: More than one-third of COVID-19 patients present neurological symptomsranging from anosmia to stroke and encephalopathy. Furthermore, pre-existingneurological conditions may require special treatment and may be associated with worseoutcomes. Notwithstanding, the role of neurologists in COVID-19 is probablyunderrecognized. Objective: The aim of this study was to report the reasons forrequesting neurological consultations by internists and intensivists in a COVID-19-dedicated hospital. Methods: This retrospective study was carried out at Hospital dasClínicas da Faculdade de Medicina da Universidade de São Paulo, Brazil, a 900-bedCOVID-19 dedicated center (including 300 intensive care unit beds). COVID-19 diagnosiswas confirmed by SARS-CoV-2-RT-PCR in nasal swabs. All inpatient neurologyconsultations between March 23rd and May 23rd, 2020 were analyzed. Neurologistsperformed the neurological exam, assessed all available data to diagnose theneurological condition, and requested additional tests deemed necessary. Difficultdiagnoses were established in consensus meetings. After diagnosis, neurologists wereinvolved in the treatment. Results: Neurological consultations were requested for 89 outof 1,208 (7.4%) inpatient COVID admissions during that period. Main neurologicaldiagnoses included: encephalopathy (44.4%), stroke (16.7%), previous neurologicaldiseases (9.0%), seizures (9.0%), neuromuscular disorders (5.6%), other acute brainlesions (3.4%), and other mild nonspecific symptoms (11.2%). Conclusions: Mostneurological consultations in a COVID-19-dedicated hospital were requested for severeconditions that could have an impact on the outcome. First-line doctors should be able torecognize neurological symptoms; neurologists are important members of the medicalteam in COVID-19 hospital care.

Introdução: Mais de um terço dos pacientes com COVID-19 apresentam sintomasneurológicos que variam de anosmia a AVC e encefalopatia. Além disso, doençasneurológicas prévias podem exigir tratamento especial e estar associadas a pioresdesfechos. Não obstante, o papel dos neurologistas na COVID-19 é provavelmentepouco reconhecido. Objetivo: O objetivo deste estudo foi relatar os motivos para solicitarconsultas neurológicas por clínicos e intensivistas em um hospital dedicado à COVID-19. Métodos: Estudo retrospectivo realizado no Hospital das Clínicas da Faculdade deMedicina da Universidade de São Paulo, Brasil, um centro dedicado à COVID-19 com900 leitos (incluindo 300 leitos para unidades de terapia intensiva). O diagnóstico deCOVID-19 foi confirmado por SARS-CoV-2-RT-PCR em swabs nasais. Todas asinterconsultas de neurologia hospitalar entre 23 de março e 23 de maio de 2020 foramanalisadas. Os neurologistas realizaram o exame neurológico, avaliaram todos os dadosdisponíveis para diagnosticar a patologia neurológica e solicitaram exames adicionaisconforme necessidade. Diagnósticos difíceis foram estabelecidos em reuniões deconsenso. Após o diagnóstico, os neurologistas participaram da condução dos casos.Resultados: Foram solicitadas consultas neurológicas para 89 de 1.208 (7,4%) empacientes internados por COVID-19 durante o período. Os principais diagnósticosneurológicos incluíram: encefalopatia (44,4%), acidente vascular cerebral (16,7%),doenças neurológicas prévias (9,0%), crises epilépticas (9,0%), transtornosneuromusculares (5,6%), outras lesões encefálicas agudas (3,4%) e outros sintomasleves inespecíficos (11,2%). Conclusões: A maioria das consultas neurológicas em umhospital dedicado à COVID-19 foi solicitada para condições graves que poderiam afetaro desfecho clínico. Os médicos na linha de frente devem ser capazes de reconhecersintomas neurológicos. Os neurologistas são membros importantes da equipe médica noatendimento hospitalar à COVID-19.

https://doi.org/10.1590/0004-282X20200089

Fair allocation of scarce medical resources during COVID-19 pandemic: ethical considerations
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Satomi, Erika

; Souza, Polianna Mara Rodrigues de

; Thomé, Beatriz da Costa

; Reingenheim, Claudio

; Werebe, Eduardo

; Troster, Eduardo Juan

; Scarin, Farah Christina de La Cruz

; Bacha, Hélio Arthur

; Grunspun, Henrique

; Ferraz, Leonardo José Rolim

; Bueno, Marco Aurelio Scarpinella

; Barros Filho, Mario Thadeu Leme de

; Borges, Pedro Custódio de Mello

einstein (São Paulo)

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2020, Volume 18 elocation eAE5775

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

https://doi.org/10.31744/einstein_journal/2020ae5775 4388 downloads

Occurrence of serological reactions for serogroup Sejroe (CTG and Prajtino) in female buffalo in the state of Pernambuco, Brazil
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Oliveira, Pollyanne Raysa Fernandes de

; Soares, Larice Bruna Ferreira

; Borges, Jonas de Melo

; Barrosa, Noelle de Castro

; Langoni, Hélio

; Brandespim, Daniel Friguglietti

; Pinheiro Junior, José Wilton

; Mota, Rinaldo Aparecido

Brazilian Journal of Microbiology

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dec 2018, Volume 49 N. 4 Pages 795 - 800

Abstract: En | Text: En | PDF: En

ABSTRACT The objective of this study was to evaluate the occurrence of anti-Leptospira spp. antibodies in female buffalo in the state of Pernambuco. A total of 123 female buffalo blood samples were collected from five properties distributed in the state of Pernambuco. The microscopic agglutination test was used to study anti-Leptospira spp. antibodies. The occurrence of anti-Leptospira spp. antibodies was 28.5% (35/123; CI 20.7–37.3%) and on different properties, the occurrence ranged from 28.6% to 80.0%, with 100% of the properties showing animals with positive results. The serovars of the serogroup Sejroe with a higher incidence were Hardjoprajtino (CTG strain, 49.1%) and Hardjo (Prajtino genotype, 43.2%), followed by serogroup Grippotyphosa with the Grippotyphosa serovar (3.9%), serogroup Pomona with the Pomona serovar (1.9%), and the Icterohaemorrhagiae serovar Copenhageni (1.9%). This was the first record of the occurrence of anti-Lepstospira spp. antibodies in female buffalo in the state of Pernambuco. Control measures are necessary to prevent health and economic losses, given that the agent involved affects animal reproduction, triggering drops in conception rates or even clinical cases of abortion.

https://doi.org/10.1016/j.bjm.2018.02.007 872 downloads

10.

Neurosyphilis and ocular syphilis clinical and cerebrospinal fluid characteristics: a case series
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Borges, Conrado Regis

; Almeida, Sérgio Monteiro de

; Sue, Karen

; Koslyk, Jéssyca Luana Alves

; Sato, Mario Teruo

; Shiokawa, Naoye

; Teive, Hélio Afonso Ghizoni

Arquivos de Neuro-Psiquiatria

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jun 2018, Volume 76 N. 6 Pages 373 - 380

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Introdução Na primeira década deste século observou-se um aumento significativo da incidência de sífilis no mundo. Objetivo Estudar características clínicas e laboratoriais da sífilis no Sistema Nervoso Central e da sífilis ocular. Métodos Estudou-se, retrospectivamente, uma série de treze casos com diagnóstico clínico e laboratorial de neurossífilis e/ou sífilis ocular, admitidos aos Serviços de Neurologia ou Neuroftalmologia do Hospital de Clínicas da Universidade Federal do Paraná. Resultados Nove pacientes tiveram diagnóstico de neurosífilis e dois destes apresentaram concomitantemente sífilis ocular. Quatro pacientes tiveram somente o diagnóstico de sífilis ocular. Dos pacientes com diagnóstico de neurosífilis, seis apresentaram meningite sifilítica sintomática, dentre os quais um se apresentou com paralisia isolada de par craniano, um com paralisia de par craniano associada sífilis ocular, dois com mielite transversa (manifestação de meningomielite), um com meningite que agravou sintomas de Miastenia Gravis e um com meningite isolada associada a sífilis ocular. Houve 3 casos de neurosífilis meningovascular. Na análise univariada, pacientes sem manifestações oculares de sífilis apresentaram maiores níveis proteína total e leucócitos do que os pacientes com sífilis ocular. Conclusão Essa série brasileira de casos de pacientes com neurosífilis e sífilis ocular destaca a alta variabilidade clínica desta doença. Alto grau de suspeição diagnóstica é necessário quando em frente a sintomas neurológicos e oculares para rápido diagnóstico e adequado manejo dos pacientes.

ABSTRACT Background During the first decade of this century, a significant increase in the incidence of syphilis was documented. Objective To study clinical and laboratory characteristics of central nervous system and ocular syphilis. Methods A retrospective case series of 13 patients with a clinical and laboratory diagnosis of neurosyphilis and/or ocular syphilis who had been admitted to the Neurology and Neuro-ophthalmology Service of the Hospital de Clínicas, Federal University of Paraná. Results Nine patients had a diagnosis of neurosyphilis and two of them also had ocular syphilis. Four patients had a diagnosis of ocular syphilis alone. Among the patients with a diagnosis of neurosyphilis, six had symptomatic syphilitic meningitis, of whom one manifested as cranial nerve palsy alone, one as cranial nerve palsy plus ocular syphilis, two as transverse myelitis (syphilitic meningomyelitis), one as meningitis worsening the patient’s myasthenia gravis symptoms and one as meningitis plus ocular syphilis. Additionally, we diagnosed three patients with meningovascular neurosyphilis. In the univariate analysis, patients without ocular syphilis showed greater levels of total protein and white blood cells in the cerebrospinal fluid than patients with ocular syphilis. Conclusion This Brazilian case series of patients with neurosyphilis and ocular syphilis highlights the wide variability of this disease. A high degree of diagnostic suspicion is necessary when facing neurological and ocular symptoms for rapid diagnosis and appropriate management of patients.

https://doi.org/10.1590/0004-282x20180054 3765 downloads

11.

Performance and carcass characteristics of lambs fed a solution of cheese whey during feedlot and pre-slaughter lairage
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Silva, Fredson Vieira e

; Borges, Iran

; Sá, Hemilly Cristina Menezes de

; Martins, Tássia Ludmila Teles

; Lana, Ângela Maria Quintão

; Borges, Ana Luiza Costa Cruz

; Moura, Marília Aparecida Fidelis e

; Costa, Hélio Henrique Araújo

Revista Brasileira de Zootecnia

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2018, Volume 47 elocation e20170026

Abstract: En | Text: En | PDF: En

ABSTRACT The objective of this study was to evaluate performance and carcass and meat characteristics of lambs fed a solution of cheese whey plus water (100 g kg−1 dry matter) (CW) during feedlot and pre-slaughter lairage. Data were analyzed as a 2 × 2 factorial (place – feedlot and slaughterhouse, food – water or CW). We evaluated the following treatments (feedlot/slaughterhouse): CW/CW, CW/water, water/CW, and control (water/water). The lambs were given a balanced diet for 70 days in the feedlot. Slaughter started 12 h after the animals arrived at the slaughterhouse. Dry matter intake, gain-to-feed ratio, average daily gain, and body weight of lambs fed CW were similar to those of control lambs. The water/CW group consumed less of this solution than the CW/CW group in the slaughterhouse. The CW supplied as a pre-slaughter supplement reduces the drip losses of lamb carcasses provided that the animals also consume it during the feedlot period. The other carcass characteristics (carcass weight, pH, subcutaneous fat thickness, and ribeye area) were similar among treatments. The meat characteristics (color, water holding capacity, cooking losses, and shear force) were similar among treatments. Whey cheese added to water can be used as an ingredient of the diet for lambs and as pre-slaughter supplement, since it does not change performance and improves carcass characteristics.

https://doi.org/10.1590/rbz4720170026 1034 downloads

12.

PREVALÊNCIA DE LESÕES CRÔNICAS DE MUNICÍPIO DA ZONA DA MATA MINEIRA (BRASIL)
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Borges, Eline Lima

; Nascimento Filho, Helio Martins do

; Pires Júnior, José Ferreira

Reme: Revista Mineira de Enfermagem

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2018, Volume 22 elocation e-1143

Abstract: En Es Pt | Text: En Es Pt | PDF: En | PDF: Es | PDF: Pt

ABSTRACT The objectives of the study were to estimate the prevalence of chronic wounds in a city of Minas Gerais, Brazil, to identify the clinical, epidemiological and sociodemographic profile of the patients with wounds and to describe the characteristics of the wounds and the treatment received. This is an exploratory, descriptive, cross-sectional study carried out in a medium-sized city in Zona da Mata/MG, with a sample of 104 participants with chronic wound from the 25 Family Health Strategy and the seven Health Centers city that met the inclusion criteria. For the data collection the participants underwent clinical evaluation, including evaluation of the wound and some data were extracted from the medical record. The estimated prevalence of chronic wounds was 0.164% (1.64 / 1,000 inhabitants); the participants had a average age of 66.6 years; most were women; with low schooling and monthly income. Most had associated illnesses and used one or more medications. The average duration of the wounds was 2 years, and most were in the legs and were of venous origin, being treated with ointments. The physician was primarily responsible for the treatment and the dressing changes were performed by the patient or caregiver. It was concluded that the prevalence obtained was compatible with the literature and the results obtained will help the nurses and managers in the organization of the care network to the user with chronic wound of the city where the research was performed. It is recommended to carry out similar studies in other cities to compare data.

RESUMEN La presente investigación buscó estimar la prevalencia de lesiones crónicas de un municipio de Minas Gerais (MG), identificar el perfil clínico, epidemiológico y sociodemográfico de los pacientes con lesión y describir las características de las lesiones y el tratamiento recibido. Estudio epidemiológico, descriptivo exploratorio, transversal realizado en un municipio mediano de la Zona de la Mata con una muestra de 104 participantes de los 25 equipos de estrategia de salud de la familia y de los siete puestos de salud del referido municipio que atendieron a los criterios de inclusión. Para la recogida de datos los participantes pasaron por una evaluación clínica, incluyendo evaluación de la lesión, además de información en el expediente clínico. La prevalencia estimada de lesiones crónicas fue 0,164% (1,64 / 1.000 habitantes), los participantes tenían edad promedio de 66,6 años; la mayoría eran mujeres; con baja escolaridad e ingreso mensual. La mayoría tenía enfermedades asociadas y usaba uno o más medicamentos. El tiempo medio de las lesiones era de 2 años y la mayoría estaba en las piernas y era de etiología venosa, tratadas con pomadas. El médico era el principal responsable del tratamiento y los cambios de curativos los hacía el paciente o cuidador. Se concluye que la prevalencia obtenida es compatible con la literatura y estos resultados ayudarán a enfermeros y gestores en la organización de la red de atención al usuario con lesión crónica del presente municipio. Se recomienda llevar a cabo estudios similares en otros municipios para poder comparar datos.

RESUMO Os objetivos do estudo foram estimar a prevalência de lesões crônicas de um município de Minas Gerais (MG), identificar o perfil clínico, epidemiológico e sociodemográfico dos pacientes com lesão e descrever as características das lesões e o tratamento recebido. Trata-se de estudo epidemiológico, descritivo exploratório, transversal realizado em um município de médio porte da Zona da Mata de MG, com amostra de 104 participantes com lesão crônica provenientes das 25 equipes de Estratégia de Saúde da Família e dos sete Postos de Saúde do referido município que atenderam aos critérios de inclusão. Para a coleta de dados os participantes passaram por avaliação clínica, incluindo a avaliação da lesão e alguns dados foram extraídos do prontuário. A prevalência estimada de lesões crônicas foi de 0,164% (1,64/1.000 habitantes), os participantes tinham idade média de 66,6 anos; a maioria eram mulheres; com baixa escolaridade e renda mensal. A maioria possuía doenças associadas e fazia uso de um ou mais medicamentos. O tempo médio de existência das lesões foi de dois anos e a maioria estava localizada nas pernas e era de etiologia venosa, sendo tratadas com pomadas. O médico era o principal responsável pelo tratamento e as trocas de curativos eram realizadas pelo paciente ou cuidador. Concluiu-se que a prevalência obtida foi compatível com a literatura e os resultados obtidos subsidiarão os enfermeiros e gestores na organização da rede de assistência ao usuário com lesão crônica do município onde a pesquisa foi realizada. Recomenda-se a realização de estudos semelhantes em outros municípios para comparação de dados.

https://doi.org/10.5935/1415-2762.20180074 6 downloads

13.

Axial Crushing of Concentric Expanded Metal Tubes Under Impact Loading
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Graciano, Carlos

; Borges, Helio

; Martínez, Gabriela

; Teixeira, Paulo

Latin American Journal of Solids and Structures

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jun 2017, Volume 14 N. 5 Pages 874 - 885

Abstract: En | Text: En | PDF: En

Abstract This paper investigates the axial crushing response of concentric expanded metal tubes under impact loading. The study is conducted by means of nonlinear finite element simulations, considering the speed of deformation and the size of the expanded metal cells. In the analysis, two tubes are placed concentrically and then axially crushed with an impact mass at various speed levels. Crushing load-displacement responses are analyzed to investigate the influence of the size of the mesh and the impact speed. The results show that specimens with the same mesh sizes increases their crushing length with increasing speed. Finally the main outcome of this investigation is to add to the state of knowledge information concerning the use of expanded metal meshes in impact attenuation devices.

https://doi.org/10.1590/1679-78253670 836 downloads

14.

Recommendations for the treatment of migraine attacks - a Brazilian consensus
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Bordini, Carlos Alberto

; Roesler, Célia

; Carvalho, Deusvenir de Souza

; Macedo, Djacir Dantas P.

; Piovesan, Élcio

; Melhado, Eliana Meire

; Dach, Fabiola

; Kowacs, Fernando

; Silva Júnior, Hilton Mariano da

; Souza, Jano Alves de

; Maciel Jr, Jayme Antunes

; Carvalho, João José de Freitas de

; Speciali, José Geraldo

; Barea, Liselotte Menke

; Queiroz, Luiz Paulo

; Ciciarelli, Marcelo Cedrinho

; Valença, Marcelo Moraes

; Lima, Márcia Maria Ferreira

; Vincent, Maurice Borges

; Jurno, Mauro Eduardo

; Monzillo, Paulo Helio

; Moreira Filho, Pedro Ferreira

; Domingues, Renan

Arquivos de Neuro-Psiquiatria

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mar 2016, Volume 74 N. 3 Pages 262 - 271

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Neste artigo um grupo de especialistas no tratamento de cefaleia da Sociedade Brasileira de Cefaleia através de um consenso elaborou medidas estratérgicas para tratar uma crise de migrânea tanto na criança como no adulto. Uma enfase particular foi dada no tratamento da migranea na mulher, incluindo gravidez, lactação e período perimenstrual.

ABSTRACT In this article, a group of experts in headache management of the Brazilian Headache Society developed through a consensus strategic measurements to treat a migraine attack in both the child and the adult. Particular emphasis was laid on the treatment of migraine in women, including at pregnancy, lactation and perimenstrual period.

https://doi.org/10.1590/0004-282X2015021 10965 downloads

15.

Vitamin D intoxication: case report
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Marins, Tatiana Aporta

; Galvão, Tatiana de Fátima Gonçalves

; Korkes, Fernando

; Malerbi, Domingos Augusto Cherino

; Ganc, Arnaldo José

; Korn, Davi

; Wagner, Jairo

; Guerra, João Carlos de Campos

; Borges Filho, Wladimir Mendes

; Ferracini, Fábio Teixeira

; Korkes, Hélio

einstein (São Paulo)

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jun 2014, Volume 12 N. 2 Pages 242 - 244

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

A hipervitaminose D é pouco relatada. Geralmente, só é percebida quando o quadro de hipercalcemia não se resolve. Em razão de seus benefícios, o uso de vitamina D aumentou nos últimos anos; consequentemente, os casos de intoxicação também tiveram aumento. Este relato destacou um caso em que o paciente apresentava piora da função renal e hipercalcemia. Após investigação, ficou confirmada a intoxicação por vitamina D devido a um erro de manipulação da droga.

Hypervitaminosis D is a rarely reported condition. In general it is only perceived when hypercalcemia is not resolved. The use of vitamin D has increased in recent years because of its benefits, but as a result, intoxication cases have occurred more frequently. This report describes a patient who presented worsening of renal function and hypercalcemia. After investigation, vitamin D intoxication was confirmed and it was due to an error in compounding.

https://doi.org/10.1590/S1679-45082014RC2860 85714 downloads

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