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Chromosomal abnormalities detected by karyotyping among patients with secondary amenorrhea: a retrospective study
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Besson, Marina da Rocha

; Taiarol, Mateus dos Santos

; Fernandes, Eliaquim Beck

; Ghiorzi, Isadora Bueloni

; Nunes, Maurício Rouvel

; Zen, Paulo Ricardo Gazzola

; Rosa, Rafael Fabiano Machado

Sao Paulo Medical Journal

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2023, Volume 141 N. 5 elocation e2022426

Abstract: En | Text: En | PDF: En

ABSTRACT BACKGROUND: Chromosomal abnormalities (CAs) have been described in patients with secondary amenorrhea (SA). However, studies on this association are scarce. OBJECTIVES: To evaluate the frequency and types of CAs detected by karyotyping in patients with SA. DESIGN AND SETTING: This retrospective study was performed in a reference clinical genetic service in South Brazil. METHODS: Data were obtained from the medical records of patients with SA who were evaluated between 1975 and 2022. Fisher’s bicaudate exact test and Student’s t-test were used, and P < 0.05 was considered significant. RESULTS: Among 43 patients with SA, 14 (32.6%) had CAs, namely del (Xq) (n = 3), 45,X (n = 2), 46,X,r(X)/45,X (n = 2), 46,XX/45,X (n = 1), 46,X,i(q10)/45,X (n = 1), 47,XXX (n = 1), 46,XX/47,XXX (n = 1), 46,XX/47,XX,+mar (n = 1), 45,XX,trob(13;14)(q10;q10)/46,XXX,trob(13;14)(q10;q10) (n = 1), and 46,XX,t(2;21)(q23;q11.2) (n = 1). Additional findings were observed mostly among patients with CA compared with those without CA (P = 0.0021). No difference in the mean age was observed between the patients with SA with or without CAs (P = 0.268025). CONCLUSIONS: CAs are common among patients with SA, especially those with short stature and additional findings. They are predominantly structural, involve the X chromosome in a mosaic, and are compatible with the Turner syndrome. Patients with SA, even if isolated, may have CAs, particularly del (Xq) and triple X.

https://doi.org/10.1590/1516-3180.2022.0426.r1.14012023

Accuracy of the urine point-of-care circulating cathodic antigen assay for diagnosing Schistosomiasis mansoni infection in Brazil: A multicenter study
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Pieri, Otavio Sarmento

; Bezerra, Fernando Schemelzer Moraes

; Coelho, Paulo Marcos Zech

; Enk, Martin Johannes

; Favre, Tereza Cristina

; Graeff-Teixeira, Carlos

; Oliveira, Ricardo Riccio

; Reis, Mitermayer Galvão dos

; Andrade, Lee Senhorinha de Almeida

; Beck, Lilian Christina Nóbrega Holsbach

; Favero, Vivian

; Fialho, Thainá Rodrigues de Souza

; Guimarães, Ricardo José de Paula Souza e

; Oliveira, Bruna Souza Santos

; Pascoal, Vanessa Fey

; Pinheiro, Marta Cristhiany Cunha

; Santos, Ronald Alves dos

; Silva, Luciano Kalabric

; Siqueira, Isadora Cristina de

; Souza, Renata Perotto de

; Katz, Naftale

Revista da Sociedade Brasileira de Medicina Tropical

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2023, Volume 56 elocation e0238-2022

Abstract: En | Text: En | PDF: En

ABSTRACT Background: The World Health Organization recommends a market-ready, urine-based point-of-care diagnostic test for circulating cathodic antigens (CCA) to determine the prevalence of S. mansoni. This study evaluated the performance of the URINE CCA (SCHISTO) ECO TESTE® (POC-ECO), which is currently available in Brazil. Methods: Residents from eight sites with different prevalence estimates provided one urine sample for POC-ECO and one stool sample for Kato-Katz (KK) and Helmintex® (HTX) testing as an egg-detecting reference for infection status. Results: None of the study sites had significantly higher POC-ECO accuracy than KK. Conclusions: POC-ECO is not currently recommended in Brazilian schistosomiasis elimination programs.

https://doi.org/10.1590/0037-8682-0238-2022

Systemic and local inflammatory response after implantation of biomaterial in critical bone injuries
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Brassolatti, Patricia

; Castro, Cynthia Aparecida de

; Santos, Hugo Leonardo dos

; Simões, Isabelle Taira

; Almeida-Lopes, Luciana

; Silva, Juliana Virginio da

; Duarte, Fernanda Oliveira

; Luna, Genoveva Lourdes Flores

; Beck, Wladimir Rafael

; Bossini, Paulo Sergio

; Anibal, Fernanda de Freitas

Acta Cirúrgica Brasileira

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2023, Volume 38 elocation e383823

Abstract: En | Text: En | PDF: En

ABSTRACT Purpose: To evaluate inflammatory response in critical bone injuries after implantation of the biomaterial composed of hydroxyapatite (HA)/poly (lactic-coglycolic acid) (PLGA)/BLEED. Methods: Forty-eight male Wistar rats (280 ± 20 grams) were divided into two groups: control group (CG), in which the animals do not receive any type of treatment; and biomaterial group (BG), in which the animals received the HA/PLGA/BLEED scaffold. Critical bone injury was induced in the medial region of the skull calotte with the aid of a trephine drill 8 mm in diameter. The biomaterial was implanted in the form of 1.5-mm thick scaffolds. Serum and calotte were collected at one, three and seven days. Results: Biomaterial had a significant effect on the morphological structure of the bone, accelerating osteoblast activation within three days, without causing exacerbated systemic inflammation. In addition, quantitative real-time polymerase chain reaction (qRT-PCR) analysis showed that BG induced upregulation of osteogenic genes such as runt-related transcription factor 2, and stimulated genes of inflammatory pathways such as tumor necrosis factor-α, on the first day without overexpressing genes related to bone matrix degradation, such as tissue inhibitor of metalloproteinases-1 and matrix metalloproteinase-9. Conclusions: The HA/PLGA/BLEED® association can be used as a bone graft to aid bone repair, as it is capable of modulating expression of important genes at this stage of the repair process.

https://doi.org/10.1590/acb383823

Conversas e interações nas visitas de famílias à exposição virtual Biodiversidade: conhecer para preservar do Museu de Zoologia da Universidade de São Paulo
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Araujo, Juliana Magalhães de

; Carneiro, Jéssica Beck

; Ribeiro, Alice

; Silva, Juliane Barros da

; Massarani, Luisa

; Scalfi, Graziele Aparecida de Moraes

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2023, Volume 29 elocation e-131259

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

Abstract The research aimed to understand the experience of 10 family groups in the virtual exhibition " Biodiversidade: conhecer para preservar", at the Museum of Zoology of the University of São Paulo, observing the conversations and interactions that took place during them. To this end, families were invited to take a virtual tour and record their interactions and conversations using the Flashback Recorder program, these recordings were then coded and analyzed using the Dedoose software. After the visit, the group participated in a semi-structured interview, which was also coded and analyzed. The results of the research indicate the importance of conversations about science during interactions between adults and children and the importance of textual elements as resources to which visitors resort to base and deepen their scientific knowledge about museum objects, also being stimuli for conversations of scientific themes. In addition, it was observed that prior interest and knowledge, even when not made explicit during the visit, incite its realization, reading of textual content, and engagement with objects.

Resumo A pesquisa objetivou compreender a experiência de visitação de dez grupos familiares à exposição virtual Biodiversidade: conhecer para preservar, do Museu de Zoologia da Universidade de São Paulo, observando as conversas e interações ocorridas durante elas. Para tal, as famílias foram convidadas a realizar a visita virtual e registrar suas interações e conversas por meio do programa Flashback Recorder, que foram codificadas e analisadas com uso do software Dedoose. Após a visita, o grupo participava de uma entrevista semiestruturada, que também foi codificada e analisada. Os resultados da pesquisa indicam o destaque das conversas sobre ciências durante as interações entre adultos e crianças e a importância dos elementos textuais enquanto recursos para os quais os visitantes recorrem para embasar e aprofundar o conhecimento científico sobre os objetos museais, sendo também estímulos para as conversas de temáticas científicas. Além disso, notou-se que o interesse e o conhecimento prévios, mesmo quando não são explicitados durante a visita, estimulam a sua realização, a leitura dos conteúdos textuais e o engajamento com os objetos.

https://doi.org/10.1590/1808-5245.29.131259

Governo Aberto na Cidade de São Paulo: Uma Análise de Políticas Públicas Abertas Paulo
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Oliveira, Daniel José Silva

; Ckagnazaroff, Ivan Beck

Revista de Administração Contemporânea

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2023, Volume 27 N. 2 elocation e210279

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Objetivo: identificar quando e como os princípios de governo aberto, especificamente transparência, participação e colaboração, estão sendo incorporados nas fases do ciclo de políticas públicas em governos locais. Marco teórico: teorias relacionadas à análise de políticas públicas e governo aberto. Método: estudo de caso único com enfoque incorporado sobre a iniciativa de governo aberto da Prefeitura Municipal de São Paulo, em que foram analisadas três políticas públicas distintas a partir de um esquema teórico-analítico construído mediante a integração da abordagem do ciclo de políticas públicas com os três princípios de governo aberto. Resultados: o estudo evidenciou que em nenhuma das políticas analisadas houve a plena incorporação desses princípios nas cinco fases do ciclo político e que pouco se avançou quanto aos requisitos necessários para que elas possam ser consideradas políticas abertas. Conclusões: o estudo contribui para estreitar a lacuna teórico-metodológica em relação à efetividade de iniciativas de governo aberto. O método oferece condições de ser aplicado em diferentes realidades e pode ser utilizado em pesquisas futuras para melhor compreender como os princípios de governo aberto estão sendo incorporados nas políticas públicas de governos que firmaram compromissos de governo aberto. Objetivo transparência colaboração locais teórico Método Paulo teóricoanalítico analítico Resultados abertas Conclusões teóricometodológica metodológica

ABSTRACT Objective: to identify how and when the open government principles, specifically transparency, participation, and collaboration, are being incorporated into the public policy cycle phases in local governments. Theoretical framework: theories related to public policy analysis and open government. Method: a single case study with an incorporated focus on the open government initiative of the São Paulo City Hall, where three distinct public policies were analyzed from a theoretical-analytical framework built by integrating the approach of the public policy cycle with the three open government principles. Results: the study showed that in none of the analyzed policies there was the full incorporation of these principles in the five phases of the policy cycle and that little progress was made regarding the requirements for them to be considered open policies. Conclusions: the study contributes to narrowing the theoretical-methodological gap concerning the effectiveness of open government initiatives. The method offers conditions to be applied in different realities and can be used in future research to better understand how open government principles are being incorporated into public policies of governments that have signed open government commitments. Objective transparency participation collaboration Method Hall theoreticalanalytical theoretical analytical Results Conclusions theoreticalmethodological methodological initiatives commitments

https://doi.org/10.1590/1982-7849rac2022210279.por

Reliability of point-of-care circulating cathodic antigen assay for diagnosing schistosomiasis mansoni in urine samples from an endemic area of Brazil after one year of storage at -20 degrees Celsius
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Favre, Tereza Cristina

; Beck, Lilian Christina Nóbrega Holsback

; Bezerra, Fernando Schemelzer Moraes

; Graeff-Teixeira, Carlos

; Coelho, Paulo Marcos Zech

; Enk, Martin Johannes

; Katz, Naftale

; Oliveira, Ricardo Riccio

; Reis, Mitermayer Galvão dos

; Pieri, Otávio Sarmento

Revista da Sociedade Brasileira de Medicina Tropical

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2022, Volume 55 elocation e0389-2021

Abstract: En | Text: En | PDF: En

ABSTRACT Background The World Health Organization recommends reliable point-of-care (POC) diagnostic testing to eliminate schistosomiasis. Lateral flow immunoassay that detects schistosome circulating cathodic antigen (CCA) in urine to establish prevalence thresholds for intervention in endemic areas is recommended. Stored urine may be useful if surveying at-risk populations is delayed or interrupted by unforeseen circumstances, such as the current COVID-19 pandemic. This study evaluated the manufacturer’s claim that Schistosoma mansoni infection can be reliably diagnosed in urine samples stored at -20°C for one year. Methods Two-hundred-forty-two subjects from an endemic site in Brazil provided one urine sample each for testing with URINE CCA (SCHISTO) ECO TESTE® (POC-ECO) and one stool sample each for testing with Kato-Katz (KK) and Helmintex® (HTX) as a robust reference standard for infection status. At least 2 ml of urine from each participant was stored at -20°C; after one year, 76 samples were randomly selected for POC-ECO retesting. Results: The POC-ECO agreement between freshly collected and stored urine was inadequate considering trace results as positive (Cohen’s kappa coefficient κ = 0.08) and negative (κ = 0.36). POC-ECO accuracy was not significantly greater than that of routine KK (54%; 95% confidence interval: 42.1%-65.5%). Conclusions The precision and accuracy of POC-ECO have to be optimized in both freshly collected and stored urine before it can be recommended for use in control programs in Brazil.

https://doi.org/10.1590/0037-8682-0389-2021

[SciELO Preprints] - TIME OF PERMANENCE IN LABORAL ACTIVITY IN EMPLOYEES OF A FITNESS CENTER DURING THE COVID-19 PANDEMIC.: FITNESS CENTER AND COVID-19 PANDEMIC
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Pitanga, Francisco José Gondim Brito, Marcus Paulo de Pitanga, Cristiano Penas Seara Beck, Carmem Cristina Nascimento, Maiara do Espírito Santo Souza, Tarcísio Chagas

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Publication date: 2021-06-01

Abstract: En Pt

Maintaining the functioning of the fitness centers during the Covid-19 pandemic can provide economic benefits, as well as important advantages for the promotion of the population's health. The objective of this study was to identify the length of time permanence on work activities for employees of a fitness center, which uses biosafety protocols, during the Covid-19 pandemic. The sample consisted of 64 employees from a fitness center in the city of Salvador, Bahia, Brazil who were followed up from August 11, 2020 to March 1, 2021 (200 days). The data were analyzed using the Kaplan-Meier survival curves. The comparison of the time curves in days, considering each variable selected until the occurrence of leave from work, in function of a positive test for Covid-19, was done through the statistical test Log-Rank. The average length of stay in work activities was 195.1 days, with only 4 (6.2%) of the total employees being away from work for testing positive for Covid-19. In contrast, 60 (93.8%) of the employees remained at work without leave by Covid-19. The variables sex and age were not identified as potential determinants of the time until the occurrence of the leave, while among administrative service employees, despite the low number, there were more absences. The results of this study indicate that the possibility of infection by Covid-19 in fitness centers seems to be low, especially when the biosafety protocols determined by the health authorities are complied.

A manutenção do funcionamento dos centros de condicionamento físico durante a pandemia da Covid-19 pode proporcionar benefícios econômicos, bem como importantes vantagens para a promoção da saúde da população. O objetivo deste estudo foi identificar o tempo de permanência nas atividades laborais em funcionários de um centro de condicionamento físico, que utiliza protocolos de biossegurança, durante a pandemia Covid-19. A amostra foi composta por 64 funcionários de um centro de condicionamento físico da cidade de Salvador, Bahia, Brasil que foram acompanhados no período de 11 de agosto de 2020 até 01 de março de 2021 (200 dias). Os dados foram analisados por meio das curvas de sobrevida de Kaplan-Meier. A comparação das curvas do tempo em dias, considerando cada variável selecionada até a ocorrência do afastamento ao trabalho, em função de teste positivo para Covid-19, foi feita através do teste estatístico Log-Rank. O tempo médio de permanência nas atividades laborais foi de 195,1 dias, com apenas 4 (6,2%) do total de funcionários sendo afastados do trabalho por testar positivo para Covid-19. Em contrapartida, 60 (93,8%) dos colaboradores permaneceram no trabalho sem afastamento por Covid-19. As variáveis sexo e idade não foram identificadas como potenciais determinantes do tempo até a ocorrência do afastamento, enquanto que entre os colaboradores de serviços administrativos, apesar do baixo quantitativo, ocorreu mais afastamentos. Os resultados deste estudo indicam que a possibilidade de infecção por Covid-19 em centros de condicionamento físico parece ser baixa, principalmente quando os protocolos de biossegurança determinados pelas autoridades sanitárias são cumpridos.

https://doi.org/10.1590/SciELOPreprints.2411

Implications for Clinical Practice from a Multicenter Survey of Heart Failure Management Centers
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Bocchi, Edimar Alcides

; Moreira, Henrique Turin

; Nakamuta, Juliana Sanajotti

; Simões, Marcus Vinicius

; Casas, Alberto de Almeida Las

; Costa, Altamiro Reis da

; Assis, Amberson Vieira de

; Durães, André Rodrigues

; Pereira-Barretto, Antonio Carlos

; Ravessa, Antonio Delduque de Araujo

; Macedo, Ariane Vieira Scarlatelli

; Biselli, Bruno

; Pinto, Carolina Maria Nogueira

; Filho, Conrado Roberto Hoffmann

; Costantini, Costantino Roberto

; Almeida, Dirceu Rodrigues

; Santos Jr, Edval Gomes dos

; Soliva Junior, Erwin

; Figueiredo, Estevão Lanna

; Albuquerque, Felipe Neves de

; Paulitsch, Felipe

; Neuenschwander, Fernando Carvalho

; Figueiredo Neto, José Albuquerque de

; Brito, Flavio de Souza

; Lopes, Heno Ferreira

; Villacorta, Humberto

; Souza Neto, João David de

; Sepulveda, João Mariano

; Ayoub, José Carlos Aidar

; Vilela-Martin, José F.

; Cardoso, Juliano Novaes

; Uemura, Laercio

; Moura, Lidia Zytynski

; Maia, Lilia Nigro

; Oliveira, Lucia Brandão de

; Maia, Lucimir

; Silva, Luís Beck da

; Gowdak, Luís Henrique Wolff

; Danzmann, Luiz Claudio

; Andrade, Marcus

; Braile-Sternieri, Maria Christiane Valeria Braga

; Moreira, Maria da Consolação Vieira

; França Neto, Olimpio R

; Filho, Otavio Rizzi Coelho

; Esteves, Paulo Frederico

; Raupp-da-Rosa, Priscila

; Silva, Ricardo Jorge de Queiroz e

; Mourilhe-Rocha, Ricardo

; Viégas, Ruy Felipe Melo

; Rassi, Salvador

; Mangili, Sandrigo

; Kaiser, Sergio Emanuel

; Martins, Silvia Marinho

; Kawabata, Vitor Sergio

Clinics

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2021, Volume 76 elocation e1991

Abstract: En | Text: En | PDF: En

OBJECTIVES: This observational, cross-sectional study based aimed to test whether heart failure (HF)-disease management program (DMP) components are influencing care and clinical decision-making in Brazil. METHODS: The survey respondents were cardiologists recommended by experts in the field and invited to participate in the survey via printed form or email. The survey consisted of 29 questions addressing site demographics, public versus private infrastructure, HF baseline data of patients, clinical management of HF, performance indicators, and perceptions about HF treatment. RESULTS: Data were obtained from 98 centers (58% public and 42% private practice) distributed across Brazil. Public HF-DMPs compared to private HF-DMP were associated with a higher percentage of HF-DMP-dedicated services (79% vs 24%; OR: 12, 95% CI: 94-34), multidisciplinary HF (MHF)-DMP [84% vs 65%; OR: 3; 95% CI: 1-8), HF educational programs (49% vs 18%; OR: 4; 95% CI: 1-2), written instructions before hospital discharge (83% vs 76%; OR: 1; 95% CI: 0-5), rehabilitation (69% vs 39%; OR: 3; 95% CI: 1-9), monitoring (44% vs 29%; OR: 2; 95% CI: 1-5), guideline-directed medical therapy-HF use (94% vs 85%; OR: 3; 95% CI: 0-15), and less B-type natriuretic peptide (BNP) dosage (73% vs 88%; OR: 3; 95% CI: 1-9), and key performance indicators (37% vs 60%; OR: 3; 95% CI: 1-7). In comparison to non- MHF-DMP, MHF-DMP was associated with more educational initiatives (42% vs 6%; OR: 12; 95% CI: 1-97), written instructions (83% vs 68%; OR: 2: 95% CI: 1-7), rehabilitation (69% vs 17%; OR: 11; 95% CI: 3-44), monitoring (47% vs 6%; OR: 14; 95% CI: 2-115), GDMT-HF (92% vs 83%; OR: 3; 95% CI: 0-15). In addition, there were less use of BNP as a biomarker (70% vs 84%; OR: 2; 95% CI: 1-8) and key performance indicators (35% vs 51%; OR: 2; 95% CI: 91,6) in the non-MHF group. Physicians considered changing or introducing new medications mostly when patients were hospitalized or when observing worsening disease and/or symptoms. Adherence to drug treatment and non-drug treatment factors were the greatest medical problems associated with HF treatment. CONCLUSION: HF-DMPs are highly heterogeneous. New strategies for HF care should consider the present study highlights and clinical decision-making processes to improve HF patient care.

https://doi.org/10.6061/clinics/2021/e1991 870 downloads

Diretriz Brasileira de Cardio-oncologia – 2020
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Hajjar, Ludhmila Abrahão

; Costa, Isabela Bispo Santos da Silva da

; Lopes, Marcelo Antônio Cartaxo Queiroga

; Hoff, Paulo Marcelo Gehm

; Diz, Maria Del Pilar Estevez

; Fonseca, Silvia Moulin Ribeiro

; Bittar, Cristina Salvadori

; Rehder, Marília Harumi Higuchi dos Santos

; Rizk, Stephanie Itala

; Almeida, Dirceu Rodrigues

; Fernandes, Gustavo dos Santos

; Beck-da-Silva, Luís

; Campos, Carlos Augusto Homem de Magalhães

; Montera, Marcelo Westerlund

; Alves, Sílvia Marinho Martins

; Fukushima, Júlia Tizue

; Santos, Maria Verônica Câmara dos

; Negrão, Carlos Eduardo

; Silva, Thiago Liguori Feliciano da

; Ferreira, Silvia Moreira Ayub

; Malachias, Marcus Vinicius Bolivar

; Moreira, Maria da Consolação Vieira

; Valente Neto, Manuel Maria Ramos

; Fonseca, Veronica Cristina Quiroga

; Soeiro, Maria Carolina Feres de Almeida

; Alves, Juliana Barbosa Sobral

; Silva, Carolina Maria Pinto Domingues Carvalho

; Sbano, João

; Pavanello, Ricardo

; Pinto, Ibraim Masciarelli F.

; Simão, Antônio Felipe

; Dracoulakis, Marianna Deway Andrade

; Hoff, Ana Oliveira

; Assunção, Bruna Morhy Borges Leal

; Novis, Yana

; Testa, Laura

; Alencar Filho, Aristóteles Comte de

; Cruz, Cecília Beatriz Bittencourt Viana

; Pereira, Juliana

; Garcia, Diego Ribeiro

; Nomura, Cesar Higa

; Rochitte, Carlos Eduardo

; Macedo, Ariane Vieira Scarlatelli

; Marcatti, Patricia Tavares Felipe

; Mathias Junior, Wilson

; Wiermann, Evanius Garcia

; Val, Renata do

; Freitas, Helano

; Coutinho, Anelisa

; Mathias, Clarissa Maria de Cerqueira

; Vieira, Fernando Meton de Alencar Camara

; Sasse, André Deeke

; Rocha, Vanderson

; Ramires, José Antônio Franchini

; Kalil Filho, Roberto

Arquivos Brasileiros de Cardiologia

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nov 2020, Volume 115 N. 5 Pages 1006 - 1043

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

https://doi.org/10.36660/abc.20201006 4180 downloads

10.

Caracterização dos óbitos e dos itinerários terapêuticos investigados pelo Comitê Municipal de Mortalidade por Aids de Porto Alegre em 2015
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Mocellin, Lucas Pitrez

; Winkler, Gerson Barreto

; Stella, Isete Maria

; Vieira, Patrícia Conzatti

; Beck, Caroline

; Behar, Paulo Renato Petersen

; Kuchenbecker, Ricardo de Souza

Epidemiologia e Serviços de Saúde

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2020, Volume 29 N. 3 elocation e2019355

Abstract: Pt En Es | Text: Pt En Es | PDF: Pt | PDF: En | PDF: Es

Resumo Objetivo caracterizar os óbitos por aids elegíveis para investigação pelo Comitê Municipal de Mortalidade por Aids (CMAids) de Porto Alegre, Brasil, em 2015, e seus itinerários terapêuticos. Métodos estudo descritivo, com dados secundários de sistemas de informações de vigilância e das fichas de investigação do CMAids. Resultados entre 336 óbitos por causas relacionadas à aids, 113 (33,6%) foram considerados evitáveis, dos quais 52 foram investigados pelo CMAids; verificou-se predomínio do sexo masculino (30/52), baixa escolaridade (29/52 casos até a 8ª série incompleta) e tempo de até 2 anos entre o diagnóstico da infecção pelo HIV e a morte (28/52); a tuberculose foi a causa de morte mais frequente (17/52); em 50/52 casos, identificou-se pelo menos uma falha no itinerário terapêutico. Conclusão os óbitos evitáveis de pessoas com aids ocorreram, majoritariamente, em pessoas do sexo masculino, de baixa escolaridade, com diagnóstico recente de HIV e em decorrência da tuberculose.

Abstract Objective to characterize AIDS deaths eligible for Porto Alegre AIDS Mortality Committee (AIDSMC) investigation, Brazil, in 2015, and their therapeutic itineraries. Methods this was a descriptive study using secondary data from surveillance information systems and AIDSMC investigation forms. Results out of 336 deaths from AIDS-related causes, 113 (33.6%) were considered avoidable, of which 52 were analyzed by AIDSMC; there was predominance of males (30/52), low schooling level (29/52 incomplete elementary education), and less than 2 years between HIV infection diagnosis and death (28/52); tuberculosis was the most frequent cause of death (17/52); and in 50/52 cases at least one therapeutic itinerary inadequacy was identified. Conclusion avoidable deaths of people with AIDS occurred mostly in men, those with low education level, those with recent HIV diagnosis and most deaths were due to tuberculosis.

Resumen Objetivo caracterizar los óbitos por sida elegibles para investigación por el Comité de Mortalidad por Sida (CMSida) de Porto Alegre, Brasil, en 2015, y sus itinerarios terapéuticos. Métodos estudio descriptivo con datos secundarios de los sistemas de información de vigilancia y formulario de investigación de CMSida. Resultados entre 336 muertes por sida, 113 (33,6%) se consideraron evitables, de las cuales 52 fueron investigadas por el CMSida; predominó el sexo masculino (30/52), el bajo nivel de educación (29/52 hasta 8º grado incompleto de primaria) y hasta 2 años entre el diagnóstico de la infección por VIH y la muerte (28/52); la tuberculosis fue la causa más frecuente de muerte (17/52); y en 50/52 casos, se identificó al menos una falla en los itinerarios terapéuticos. Conclusión las muertes evitables de personas con sida ocurrieron principalmente en hombres, con baja escolaridad, diagnóstico reciente de VIH y debido a la tuberculosis.

https://doi.org/10.5123/s1679-49742020000300009

11.

Caracterização dos óbitos e dos itinerários terapêuticos investigados pelo Comitê Municipal de Mortalidade por Aids de Porto Alegre em 2015
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Mocellin, Lucas Pitrez

; Winkler, Gerson Barreto

; Stella, Isete Maria

; Vieira, Patrícia Conzatti

; Beck, Caroline

; Behar, Paulo Renato Petersen

; Kuchenbecker, Ricardo de Souza

Epidemiologia e Serviços de Saúde

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2020, Volume 29 N. 3 elocation e2019355

Abstract: Pt En Es | Text: Pt En Es | PDF: Pt | PDF: En | PDF: Es

https://doi.org/10.5123/s1679-49742020000300009 727 downloads

12.

Guideline of the Brazilian Society of Cardiology on Telemedicine in Cardiology - 2019
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Lopes, Marcelo Antônio Cartaxo Queiroga

; Oliveira, Gláucia Maria Moraes de

; Ribeiro, Antonio Luiz Pinho

; Pinto, Fausto J.

; Rey, Helena Cramer Veiga

; Zimerman, Leandro Ioschpe

; Rochitte, Carlos Eduardo

; Bacal, Fernando

; Polanczyk, Carisi Anne

; Halperin, Cidio

; Araújo, Edson Correia

; Mesquita, Evandro Tinoco

; Arruda, José Airton

; Rohde, Luis Eduardo Paim

; Grinberg, Max

; Moretti, Miguel

; Caramori, Paulo Ricardo Avancini

; Botelho, Roberto Vieira

; Brandão, Andréa Araújo

; Hajjar, Ludhmila Abrahão

; Santos, Alexandre Fonseca

; Colafranceschi, Alexandre Siciliano

; Etges, Ana Paula Beck da Silva

; Marino, Bárbara Campos Abreu

; Zanotto, Bruna Stella

; Nascimento, Bruno Ramos

; Medeiros, Cesar Rocha

; Santos, Daniel Vitor de Vasconcelos

; Cook, Daniela Matos Arrowsmith

; Antoniolli, Eduardo

; Souza Filho, Erito Marques de

; Fernandes, Fábio

; Gandour, Fabio

; Fernandez, Francisco

; Souza, Germano Emilio Conceição

; Weigert, Guilherme de Souza

; Castro, Iran

; Cade, Jamil Ribeiro

; Figueiredo Neto, José Albuquerque de

; Fernandes, Juliano de Lara

; Hadlich, Marcelo Souza

; Oliveira, Marco Antonio Praça

; Alkmim, Maria Beatriz

; Paixão, Maria Cristina da

; Prudente, Maurício Lopes

; Aguiar Netto, Miguel A. S.

; Marcolino, Milena Soriano

; Oliveira, Monica Amorim de

; Simonelli, Osvaldo

; Lemos Neto, Pedro A.

; Rosa, Priscila Raupp da

; Figueira, Renato Minelli

; Cury, Roberto Caldeira

; Almeida, Rodrigo Coelho

; Lima, Sandra Regina Franco

; Barberato, Silvio Henrique

; Constancio, Thiago Inocêncio

; Rezende, Wladimir Fernandes de

Arquivos Brasileiros de Cardiologia

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nov 2019, Volume 113 N. 5 Pages 1006 - 1056

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

https://doi.org/10.5935/abc.20190205 5274 downloads

13.

Size and shape-controlled nanomaterials based on modified polyol and thermal decomposition approaches. A brief review.
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VARANDA, LAUDEMIR C.

; SOUZA, CAIO G.S.

; MORAES, DANIEL A.

; NEVES, HERBERT R.

; SOUZA JUNIOR, JOÃO B.

; SILVA, MONICA F.

; BINI, RAFAEL A.

; ALBERS, REBECCA F.

; SILVA, TIAGO L.

; BECK JUNIOR, WATSON

Anais da Academia Brasileira de Ciências

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2019, Volume 91 N. 4 elocation e20181180

Abstract: En | Text: En | PDF: En

Abstract: Since its inception in 2007, the Colloidal Materials Group, one of the research groups in nanotechnology of the Institute of Chemistry of São Carlos (IQSC) at University of São Paulo (USP) carries out studies related to the development of syntheses methods of nanoparticles and multifunctional nanostructured systems. Our works search new synthesis methodologies that allow high size and shape control of the individual nanoparticles or that compose the nanostructured systems and has as a principle the synthetic approaches based on the modified polyol and thermal decomposition processes. Systems involving nanoparticles have received extensive attention both in the fundamental research and in several technological applications exploring the unique properties presented in nanomaterials. These properties are strongly size- and shape-dependent of the nanoparticles and a large distribution of size or shape implies in a high response dispersion, justifying the intense research for the so-called nanoparticle monodisperse systems. In this review, we present the main aspects to obtain monodisperse nanoparticulate systems, correlating with the synthesis processes used in our group and some of our results in systems involving nanoparticles with magnetic, optical, and electronic properties, as well as some obtained composite materials for different applications.

https://doi.org/10.1590/0001-3765201920181180 4176 downloads

14.

Metabolic profile and spontaneous physical activity modulation under short-term food restriction in young rats.
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Beck, Wladimir Rafael

; Scariot, Pedro Paulo Menezes

; Carmo, Stefânia Santos do

; Manchado-Gobatto, Fúlvia Barros

; Gobatto, Claudio Alexandre

Motriz: Revista de Educação Física

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2017, Volume 23 N. spe elocation e101606

Abstract: En | Text: En | PDF: En

Abstract AIMS The aim of this study was to investigate the effects of short-term food restriction (6-weeks) on metabolic profile and spontaneous physical activity (SPA) of young male Wistar rats. METHODS Thirty rats had their baseline SPA measured at 21 days-old and were separated into two groups at 28 days-old: Control (CG) and 50% of food restriction (FR). The food restriction protocol lasted six weeks, being the SPA measured weekly by a gravimetric apparatus. At the end of the experiment, biochemical analyses were performed in serum and tissue samples with statistical significance set at 5%. RESULTS FR showed less SPA than CG, as occurred for body mass, water intake, adipose tissue and liver, heart and soleus glycogen, serum glucose, total protein, triglycerides and total cholesterol (P<0.05). CONCLUSION Data set demonstrates that low substrate stores signaled to decrease spontaneous physical activity to save energy.

https://doi.org/10.1590/s1980-6574201700si0013 866 downloads

15.

Percepções Locais Sobre os Solos e seu Uso no Município de Gravataí, RS
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Finato, Tatiana

; Nascimento, Paulo César do

; Beck, Fábio de Lima

; Tornquist, Carlos Gustavo

; Caetano, Luís Augusto Martins

; Fedrizzi, Thiago Zilles

Revista Brasileira de Ciência do Solo

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jun 2015, Volume 39 N. 3 Pages 915 - 923

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Gravataí é um município da região metropolitana de Porto Alegre com potencial para desenvolvimento agrícola, a partir de uma maior integração entre os produtores e os serviços de pesquisa e extensão. Os objetivos gerais deste trabalho foram compreender as percepções e os conhecimentos locais sobre o recurso natural “solo” e as terras, bem como a lógica dos sistemas de produção; e relacionar tal conhecimento com a classificação e avaliação dos solos por critérios acadêmicos. Realizou-se uma entrevista semiestruturada em cinco unidades produtivas (UP), fazendo um levantamento de dados referente à família e às UP; a caminhada transversal nas UP e o levantamento expedito de solo com participação dos produtores e integrantes das famílias. As observações de campo dos produtores foram relacionadas com a descrição morfológica e os resultados analíticos obtidos a partir da amostragem dos perfis de solo. Os resultados evidenciaram a sistematização dos conhecimentos dos produtores em relação aos solos e demais fatores do ambiente, permitindo estabelecer uma distribuição geográfica, relação com o ambiente e critérios para uso e manejo. É perceptível a relação entre as formas de conhecimento local e acadêmico, constituindo potencial para planejamento e consolidação de sistemas de produção sustentáveis.

Gravatai is a municipality within the metropolitan region of Porto Alegre, State of Rio Grande do Sul, with great potential for agricultural development based on greater interaction between producers and research and extension services. The main objectives of this study were to understand local perceptions and knowledge about the natural resources of soils and landscapes, as well as the logic of production systems; and to evaluate the linkage of this knowledge with soil classification and evaluation made through academic criteria. Semi-structured interviews were carried out in the five production units (PU) studied, conducting a survey of data related to the PU and workers families, a walk across the PU, and a rapid survey of the soil with the participation of producers and family members. Field observations from family farmers were related to morphological descriptions and the analytic results obtained from soil profile sampling. Results obtained showed that there is systematization of farmers’ knowledge concerning soil and other natural resources, allowing geographic soil distribution, relation to the environment, and criteria for use and management to be established. Results obtained also showed a clear relationship between local and academic knowledge, constituting potential for planning and consolidation of sustainable production systems.

https://doi.org/10.1590/01000683rbcs20140514 2940 downloads

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