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Developmental predictors of mathematics achievement at the end of Year 1
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Martins, Sara

; Araújo, Carolina A.

; Fonseca, Marisa

; Baptista, Joana

; Martins, Carla

Análise Psicológica

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dec 2023, Volume 41 N. 2 Pages 177 - 190

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo: O presente estudo analisou o papel preditor das dimensões cognitivas, sociais, emocionais e comportamentais de crianças avaliadas aos 4 anos e meio de idade, bem como das variáveis tradicionalmente associadas à prontidão escolar académica antes da entrada no ensino primário, no desempenho da Matemática no final do 1.º ano. Participaram neste estudo longitudinal um total de 58 crianças Portuguesas e respetivos pais. As correlações iniciais demonstraram associações significativas entre o quociente de inteligência (QI) da criança, controlo inibitório, flexibilidade cognitiva, perfil de desregulação, prontidão escolar académica e o seu desempenho subsequente na Matemática. Através de uma análise de regressão hierárquica verificou-se que o controlo inibitório aos 4 anos e meio previu significativamente o desempenho na Matemática no final do 1.º ano, superando o efeito da prontidão escolar académica antes da entrada no ensino primário. Estes resultados contribuem para a literatura existente, salientando o impacto do funcionamento executivo da criança, avaliado durante a idade pré-escolar, no desempenho posterior na Matemática nos primeiros anos do ensino formal.

Abstract: This study examined the predictive role of child cognitive, social, emotional, and behavioural dimensions assessed at the age of 4½, as well as of the traditional variables related to academic school readiness before the entry to primary school, on mathematics achievement at the end of Year 1. A sample of 58 Portuguese children and their parents participated in this longitudinal study. Initial correlations indicated significant associations between child intelligence quotient (IQ), inhibitory control, set-shifting, dysregulation profile, academic school readiness, and their subsequent performance in mathematics. A hierarchical regression analysis showed that inhibitory control at 4½ years significantly predicted mathematics achievement at the end of Year 1 over and above the effect of academic school readiness before entering primary school. These results add to the existing literature by highlighting the impact of child executive functioning assessed during the preschool years on subsequent mathematics performance in early school years.

https://doi.org/10.14417/ap.2037

RESVECH 2.0: cross-cultural adaptation for Brazil, reliability and validity for the evaluation of venous ulcers
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Menegon, Marina Rosa

; Malaquias, Suelen Gomes

; Silva, Joana Aragão da

; Oliveira, Beatriz Guitton Renaud Baptista de

; Medrano, Juan Carlos Restrepo

; Verdú-Soriano, José

; Bachion, Maria Márcia

Revista Brasileira de Enfermagem

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2023, Volume 76 N. 2 elocation e20220185

Abstract: En Es Pt | Text: En Es Pt | PDF: En | PDF: Es | PDF: Pt

ABSTRACT Objectives: to cross-culturally adapt the scale Resultados en la valoración y evolución de la cicatrización de las heridas - RESVECH 2.0 for Brazilian Portuguese; to estimate the internal consistency and construct and criterion validity of the scale in the evaluation of venous ulcers. Methods: methodological study, based on international guidelines for studies of this type. Wounds were evaluated using the RESVECH 2.0 and Pressure Ulcer Scale of Healing 3.0 (PUSH). Descriptive analysis, confirmatory factor analysis, Cronbach’s alpha and Spearman’s correlation (p<0.05) were used. Results: 12 nurses and 77 people with 153 venous ulcers participated in the study. The translation was successful, the proposed factor model was validated, and Cronbach ‘s alpha = 0.832 (95%CI, 0.780-0.880) and correlation coefficient (RESVECH 2.0 and PUSH 3.0) = 0.74 were obtained. Conclusions: the adaptation of RESVECH 2.0 to Brazilian Portuguese is robust. Reliability and validity show compatibility for use in the country in the evaluation of venous ulcers.

RESUMEN Objetivos: adaptar transculturalmente la escala “Resultados en la valoración y evolución de la cicatrización de heridas”, RESVECH 2.0 al portugués de Brasil; estimar su consistencia interna, validez de constructo y de criterio para su utilización en úlceras varicosas. Métodos: es un estudio metodológico, basado en directivas internacionales sobre investigaciones de esta naturaleza. Se evaluaron las heridas por medio de la RESVECH 2.0 y de la Escala de Cicatrización de Úlceras por Presión 3.0 (PUSH). Se llevó a cabo con análisis descriptivo, análisis factorial confirmatorio, alfa de Cronbach y correlación de Spearman (p<0,05). Resultados: participaron 12 enfermeros y 77 personas que tenían 153 úlceras venosas. La traducción fue exitosa, el modelo factorial propuesto fue validado, el alfa de Cronbach = 0,832 (95%CI=0,780-0,880) y el coeficiente de correlación (RESVECH 2.0 y PUSH 3.0) = 0,74. Conclusiones: la adaptación de la RESVECH 2.0 al portugués brasileño es sólida. La fiabilidad y la validez demuestran la compatibilidad para su utilización en el país en la evaluación de las úlceras varicosas.

RESUMO Objetivos: adaptar transculturalmente a escala Resultados en la valoración y evolución de la cicatrización de las heridas - RESVECH 2.0 para o português do Brasil; estimar sua consistência interna, validade de construto e de critério para utilização em úlceras venosas. Métodos: estudo metodológico, baseado em diretrizes internacionais para estudos dessa natureza. Realizou-se avaliação das feridas por meio da RESVECH 2.0 e da Pressure Ulcer Scale of Healing 3.0 (PUSH). Empregou-se análise descritiva, análise fatorial confirmatória, alfa de Cronbach e correlação de Spearman (p<0,05). Resultados: participaram 12 enfermeiros e 77 pessoas com 153 úlceras venosas. A tradução foi bem-sucedida, o modelo fatorial proposto foi validado, obteve-se alfa de Cronbach = 0,832 (IC95%=0,780-0,880) e coeficiente de correlação (RESVECH 2.0 e PUSH 3.0) = 0,74. Conclusões: a adaptação da RESVECH 2.0 para o português do Brasil é robusta. A confiabilidade e validade evidenciam compatibilidade para utilização no país e avaliação de úlceras venosas.

https://doi.org/10.1590/0034-7167-2022-0185

Controlling parenting and executive functioning in children born preterm
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Toscano, Carolina

; Sá, Cindy

; Baptista, Joana

; Moutinho, Vanessa

; Soares, Isabel

Psicologia

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dec 2022, Volume 36 N. 2 Pages 66 - 73

Abstract: En | Text: En | PDF: En

Abstract This study investigated the relations between mothers’ and fathers’ controlling behaviors and the executive functioning of children born preterm. Sixty-eight preterm children and their parents were assessed when the children were 3 ½ years old. The executive functioning was measured using the Head-to-Toes-Task and controlling parenting behaviors were measured through a standardized observation of a parent-child interaction. Hierarchical regression analysis showed that both mothers’ and fathers’ controlling behaviors were associated with worse child executive functioning performance, after controlling for the child’s cognitive ability. Findings suggest that both mothers and fathers play an important role in the development of executive functioning of children born prematurely, highlighting the need to consider both parents in the study of and intervention with these children.

https://doi.org/10.17575/psicologia.1754

The Influence of Schmorl Nodes in Spinal Sagittal Balance in Young Adults
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Silva, Joana Gomes da

; Baptista, Mário

; Direito-Santos, Bruno

; Varanda, Pedro

; Duarte, Rui M.

Revista Brasileira de Ortopedia

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oct 2022, Volume 57 N. 5 Pages 815 - 820

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Objetivos O presente estudo tem como objetivo caracterizar o equilíbrio sagital (SB, na sigla em inglês) espinhal em adultos jovens com nódulos de Schmorl (NS). Métodos Este é um estudo transversal de uma amostra composta por 47 adultos jovens. Ressonância magnética (RM) lombar foi usada para separar os pacientes em um grupo com NS e um grupo controle. Radiografias da coluna vertebral em pé foram usadas para comparar os parâmetros espinopélvicos do SB entre os grupos: eixo vertical sagital, cifose torácica, lordose lombar (LL), incidência pélvica (PI, na sigla em inglês), inclinação pélvica (PT, na sigla em inglês) e inclinação sacral (SS, na sigla em inglês). Resultados Os valores de LL e SS foram significativamente menores nos pacientes com NS em comparação com o grupo controle (54,5° versus 64,3°; 36,2° versus 41,4°, respectivamente). Não foram observadas diferenças significativas nos demais parâmetros. Os dois grupos apresentaram correlações significativas entre LL e SS, PI e PT e PI e SS. Conclusões Adultos jovens com NS apresentam modificações associadas ao SB, principalmente valores menores de LL e SS, em comparação com o grupo controle. Este perfil mais plano assemelha-se ao observado em pacientes com lombalgia e patologia discal em estágio inicial. Acreditamos que o NS seja um achado clínico relevante que deve levar ao estudo do SB de um paciente por poder revelar variações associadas aos primeiros estágios de degeneração discal. Nível de Evidência III

Abstract Objectives The present study aims to characterize the spinal balance (SB) in young adults with Schmorl nodes (SN). Methods A cross-sectional study was conducted on a sample of 47 young adults. Lumbar magnetic resonance imaging (MRI) was used to divide the patients into an SN group and a control group. Standing full spine radiographs were used to compare the spinopelvic SB parameters between groups: sagittal vertical axis, thoracic kyphosis, lumbar lordosis (LL), pelvic incidence (PI), pelvic tilt (PT), and sacral slope (SS). Results The LL and SS values were significantly lower in patients with SN when compared with the control group (54.5° versus 64.3°; 36.2° versus 41.4°, respectively). No significant differences were observed for the other parameters. Significant correlations were found in both groups between LL and SS; PI and PT; and PI and SS. Conclusions Young adults with SN have associated SB modifications, particularly lower LL and SS values, when compared with a control group. This flatter profile resembles that observed in patients with lower back pain and early disc pathology. We believe that SNs are relevant clinical findings that should prompt the study of the SB of a patient, as it may uncover variations associated with early disc degeneration. Level of Evidence III

https://doi.org/10.1055/s-0042-1744501

Long COVID in children and adolescents: Is it real?
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Lima, Joana Baptista de

; Fernandes, Alexandre

; Teixeira, Carla

; Marques, Laura

Nascer e Crescer

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sep 2022, Volume 31 N. 3 Pages 260 - 265

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

Abstract Introduction : While acute COVID-19 symptoms are well defined and described, long-term symptoms are not. Most patients achieve full recovery within 3-4 weeks after the onset of the infection, but in some cases, symptoms persist weeks or months after recovery. Although extensively studied in adults, COVID-19 data in pediatric patients remains scarce. Objective : To review the available literature regarding Long COVID syndrome in children and adolescents. Methods : A brief literature review was conducted on PubMed and Google Scholar databases using the terms “Long COVID”, “post-COVID”, “persistent COVID” AND “children”, “adolescents”, “pediatric”. Results : Seventeen articles were eligible for this review. The prevalence of Long COVID was highly variable, ranging from 2 to 66%. The most commonly reported symptoms were fatigue, shortness of breath, headache, sleep disturbance, concentration difficulties, chronic cough, dizziness, myalgia, chest pain, poor sense of smell or anosmia, abdominal pain, and loss of appetite or weight. Older age, muscle pain on admission, Intensive Care Unit admission, allergic diseases, higher body mass index, and longer duration of infection were risk factors identified for the development of Long COVID. Six studies included a control group; four reported differences between groups, with more symptoms in the group of cases, and one reported no differences between groups. Conclusion : Long COVID represents a significant public health concern, which should be studied to enable the development of protective measures, rehabilitation programs, and specific guidelines. Appropriate case-control studies are important to better discriminate between symptoms associated with SARS-CoV-2 and those associated with the pandemic.

Resumo Introdução : Os sintomas agudos associados à COVID-19 estão bem definidos e descritos, contrariamente aos sintomas a longo prazo. A maioria dos doentes recupera totalmente em 3-4 semanas após a infeção, mas em alguns casos os sintomas podem persistir durante semanas ou meses. Embora esta entidade se encontre amplamente estudada na população adulta, a evidência em idade pediátrica permanece escassa. Objetivo : Rever a literatura disponível sobre COVID Longa em crianças e adolescentes. Métodos : Revisão da literatura nas bases de dados PubMed e Google Académico utilizando os termos “Long COVID”, “post-COVID” “persistent COVID” AND “children”, “adolescents”, “pediatric”. Resultados : Foram identificados dezassete artigos nas bases de dados consideradas. A prevalência de COVID Longa foi muito variável, entre 2─66%. Os sintomas mais comuns foram fadiga, dispneia, cefaleias, distúrbios do sono, dificuldades de concentração, tosse crónica, tonturas, mialgia, toracalgia, anosmia, dor abdominal e perda de apetite ou peso. Idade avançada, mialgia na altura da admissão, necessidade de internamento em Unidade de Cuidados Intensivos, antecedentes de doença alérgica, índice de massa corporal elevado e duração mais longa de infeção foram identificados como fatores de risco para o desenvolvimento de COVID Longa. Seis estudos incluíram um grupo controlo; quatro identificaram diferenças entre grupos, com mais sintomas no grupo de casos, enquanto um não identificou diferenças entre grupos. Conclusão : A síndrome de COVID Longa representa um importante problema de saúde pública, sendo necessária uma melhor compreensão da mesma para estabelecer medidas de proteção, programas de reabilitação e orientações específicas. Estudos caso-controlo apropriados são importantes para discriminar se os sintomas observados estão associados à infeção por SARS-CoV-2 ou à pandemia.

https://doi.org/10.25753/birthgrowthmj.v31.i3.27683

Guidelines on COVID-19 vaccination in patients with immune-mediated rheumatic diseases: a Brazilian Society of Rheumatology task force
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Tavares, Anna Carolina Faria Moreira Gomes

; Melo, Ana Karla Guedes de

; Cruz, Vítor Alves

; Souza, Viviane Angelina de

; Carvalho, Joana Starling de

; Machado, Ketty Lysie Libardi Lira

; Valadares, Lilian David de Azevedo

; Reis Neto, Edgard Torres dos

; Rezende, Rodrigo Poubel Vieira de

; Guimarães, Maria Fernanda Brandão de Resende

; Ferreira, Gilda Aparecida

; Braz, Alessandra de Sousa

; Vieira, Rejane Maria Rodrigues de Abreu

; Pinheiro, Marcelo de Medeiros

; Ribeiro, Sandra Lúcia Euzébio

; Bica, Blanca Elena Gomes Rios

; Baptista, Kátia Lino

; Costa, Izaias Pereira da

; Marques, Claudia Diniz Lopes

; Lopes, Maria Lúcia Lemos

; Martinez, José Eduardo

; Giorgi, Rina Dalva Neubarth

; Mota, Lícia Maria Henrique da

; Loures, Marcos Antônio Araújo da Rocha

; Paiva, Eduardo dos Santos

; Monticielo, Odirlei André

; Xavier, Ricardo Machado

; Kakehasi, Adriana Maria

; Pileggi, Gecilmara Cristina Salviato

Advances in Rheumatology

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2022, Volume 62 elocation 3

Abstract: En | Text: En | PDF: En

Abstract Objective: To provide guidelines on the coronavirus disease 2019 (COVID-19) vaccination in patients with immune-mediated rheumatic diseases (IMRD) to rheumatologists considering specific scenarios of the daily practice based on the shared-making decision (SMD) process. Methods: A task force was constituted by 24 rheumatologists (panel members), with clinical and research expertise in immunizations and infectious diseases in immunocompromised patients, endorsed by the Brazilian Society of Rheumatology (BSR), to develop guidelines for COVID-19 vaccination in patients with IMRD. A consensus was built through the Delphi method and involved four rounds of anonymous voting, where five options were used to determine the level of agreement (LOA), based on the Likert Scale: (1) strongly disagree; (2) disagree, (3) neither agree nor disagree (neutral); (4) agree; and (5) strongly agree. Nineteen questions were addressed and discussed via teleconference to formulate the answers. In order to identify the relevant data on COVID-19 vaccines, a search with standardized descriptors and synonyms was performed on September 10th, 2021, of the MEDLINE, EMBASE, Cochrane Central Register of Controlled Trials, ClinicalTrials.gov, and LILACS to identify studies of interest. We used the Newcastle–Ottawa Scale to assess the quality of nonrandomized studies. Results: All the nineteen questions-answers (Q&A) were approved by the BSR Task Force with more than 80% of panelists voting options 4—agree—and 5—strongly agree—, and a consensus was reached. These Guidelines were focused in SMD on the most appropriate timing for IMRD patients to get vaccinated to reach the adequate covid-19 vaccination response. Conclusion: These guidelines were developed by a BSR Task Force with a high LOA among panelists, based on the literature review of published studies and expert opinion for COVID-19 vaccination in IMRD patients. Noteworthy, in the pandemic period, up to the time of the review and the consensus process for this document, high-quality evidence was scarce. Thus, it is not a substitute for clinical judgment.

https://doi.org/10.1186/s42358-022-00234-7

Bacterial communities in soils as indicators of the potential of syenite as an agromineral
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Baptista, Joana de Carvalho

; Gray, Neil Duncan

; Tarumoto, Miriam Büchler

; Singleton, Ian

; McCann, Clare Maria

; Manning, David Andrew Charles

Pesquisa Agropecuária Brasileira

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2022, Volume 57 elocation e01414

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo O objetivo deste trabalho foi identificar comunidade microbianas associadas às superfícies de feldspato alcalino e determinar se esses micróbios podem estar envolvidos no intemperismo dessas rochas, para benefício agronômico. As amostras foram coletadas de perfis intemperizados e solos desenvolvidos sobre um sienito, considerado como matéria prima para produção de agrominerais, localizado no município de Triunfo, no estado de Pernambuco, Brasil. Foram usadas técnicas de microbiologia molecular (qPCR e sequenciamento de genes 16S rRNA), e os dados foram analisados por análise de variância, análise de grupos hierárquicos e análises de coordenadas principais. Além disso, utilizou-se a microscopia eletrônica de varredura para gerar imagens das superfícies minerais. Foram observadas comunidades similares em todas as amostras, o que mostra que as bactérias encontradas nos solos estão presentes nos estágios iniciais do intemperismos da rocha e estão disponíveis para desempenhar um papel na liberação de nutrientes. Em particular, Actinobacteria e, dentro desse filo, Actinomycetales, foram proporcionalmente mais abundantes do que os outros táxons nas amostras de solo dominadas por rochas, isto é, em solos finos sobre ou entre sienito fraturado ou quebrado. A análise do pó de rocha usado como remineralizador, moído sem outros tratamentos, mostra que Actinobacteria desempenham um papel nos estágios iniciais do intemperismo de rochas compostas por feldspatos.

Abstract The objective of this work was to identify microbial communities associated with the surfaces of alkali feldspars and to determine whether these microbes might be involved in the weathering of these rocks for agronomic benefit. Samples were taken from weathering profiles and soils developed on a syenite, considered as a raw material for agromineral production, located in the municipality of Triunfo, in the state of Pernambuco, Brazil. Molecular microbiological techniques (qPCR and 16S rRNA gene sequencing) were used, and data were interpreted by the analysis of variance, hierarchical cluster analysis, and principal coordinates analysis. In addition, scanning electron microscopy was used to image mineral surfaces. Similar bacterial communities were observed in all samples, showing that the bacteria found in soil are present at the earliest stages of rock weathering and are available to play a role in nutrient release. In particular, Actinobacteria and, within this phylum, Actinomycetales were proportionally more abundant than other taxa in rock-dominated soil samples, i.e., in thin soils on or between fractured or broken syenite. The analysis of rock dust used as a remineralizer, crushed with no further treatment, shows that Actinobacteria play a role in the early stages of weathering of feldspar-bearing rocks.

https://doi.org/10.1590/s1678-3921.pab2022.v57.01414

Adipose tissue-derived stromal/stem cells + cholecalciferol: a pilot study in recent-onset type 1 diabetes patients
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Dantas, Joana Rodrigues

; Araújo, Débora Batista

; Silva, Karina Ribeiro

; Souto, Débora Lopes

; Pereira, Maria de Fátima Carvalho

; Luiz, Ronir Raggio

; Mantuano, Matheus dos Santos

; Claudio-da-Silva, Cesar

; Gabbay, Monica Andrade Lima

; Dib, Sérgio Atala

; Couri, Carlos Eduardo Barra

; Maiolino, Angelo

; Rebelatto, Carmen Lúcia Kuniyoshi

; Daga, Débora Regina

; Senegaglia, Alexandra Cristina

; Brofman, Paulo Roberto Slud

; Baptista, Leandra S.

; Oliveira, José Egídio Paulo de

; Zajdenverg, Lenita

; Rodacki, Melanie

Archives of Endocrinology and Metabolism

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jun 2021, Volume 65 N. 3 Pages 342 - 351

Abstract: En | Text: En | PDF: En

ABSTRACT Objective: Adipose tissue-derived stromal/stem cells (ASCs) and vitamin D have immunomodulatory actions that could be useful for type 1 diabetes (T1D). We aimed in this study to investigate the safety and efficacy of ASCs + daily cholecalciferol (VIT D) for 6 months in patients with recent-onset T1D. Materials and methods: In this prospective, dual-center, open trial, patients with recent onset T1D received one dose of allogenic ASC (1 x 106 cells/kg) and cholecalciferol 2,000 UI/day for 6 months (group 1). They were compared to patients who received chol-ecalciferol (group 2) and standard treatment (group 3). Adverse events were recorded; C-peptide (CP), insulin dose and HbA1c were measured at baseline (T0), after 3 (T3) and 6 months (T6). Results: In group 1 (n = 7), adverse events included transient headache (all), mild local reactions (all), tachycardia (n = 4), abdominal cramps (n = 1), thrombophlebitis (n = 4), scotomas (n = 2), and central retinal vein occlusion at T3 (n = 1, resolution at T6). Group 1 had an increase in basal CP (p = 0.018; mean: 40.41+/-40.79 %), without changes in stimulated CP after mixed meal (p = 0.62), from T0 to T6. Basal CP remained stable in groups 2 and 3 (p = 0.58 and p = 0.116, respectively). Group 1 had small insulin requirements (0.31+/- 0.26 UI/kg) without changes at T6 (p = 0.44) and HbA1c decline (p = 0.01). At T6, all patients (100%; n = 7) in group 1 were in honeymoon vs 75% (n = 3/4) and 50% (n = 3/6) in groups 2 and 3, p = 0.01. Conclusions: Allogenic ASC + VIT D without immunosuppression was safe and might have a role in the preservation of β-cells in patients with recent-onset T1D. ClinicalTrials.gov: NCT03920397.

https://doi.org/10.20945/2359-3997000000368 236 downloads

Os Serviços Farmacêuticos CUF Infante Santo no Combate à Pandemia COVID-19: Dias Difíceis, Dedicação Incondicional
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Pereira, Maria Teresa

; Oliveira, Rita

; Baptista, Maria

; Cardoso, Joana

; Vilaverde, Rita

; Cabeças, Teresa

; Sá, Francisco

; Pinto, Beatriz

; Ventim, Ana Maria

; Ribeiro, Gabriela

; Franco, Sara

; Cunha, Marta

; Gouveia, Inês Melo

; Galvão, Manuel

Gazeta Médica

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jun 2020, Volume 7 N. 2 Pages 156 - 162

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Em dezembro de 2019, uma doença respiratória causada por um novo coronavírus, SARS-CoV-2, foi identificada pela primeira vez na China. Rapidamente assumiu contornos pandémicos, levando a Organização Mundial da Saúde (OMS) a declarar pandemia a COVID-19 no início de março de 2020. Viver uma pandemia, ou outro evento major de saúde pública, não é habitual e testa o sistema de saúde, assim como a resiliência dos profissionais. A reorganização rápida, a flexibilidade dos profissionais e o trabalho interdisciplinar, permitiu coordenar esforços antes da emergência e garantir que os recursos seriam aproveitados em toda a sua extensão. Um dos papéis fundamentais dos farmacêuticos hospitalares é garantir a disponibilidade e o fornecimento oportuno da terapia mais segura e eficaz. Para isso, os farmacêuticos devem planear, identificar e mitigar a escassez de medicamentos (fornecedores limitados de matérias-primas) e intervir aquando da validação da terapêutica, principalmente em contexto off-label, evitando erros de medicação, omissões de terapêuticas habituais, reações adversas e contribuindo para uma “medicina de precisão” num cenário tão desconhecido.

Abstract In December 2019, a respiratory disease caused by a new coronavirus, SARS-CoV-2, was first identified in China. It quickly took on pandemic contours, prompting the World Health Organization (WHO) to declare a pandemic to COVID-19 in early March 2020. Experiencing a pandemic, or other major public health event, is unusual and tests the health system, as well as the resilience of professionals. The rapid reorganization, the flexibility of the professionals and the interdisciplinary work, allowed to coordinate efforts before the emergency and to guarantee that the resources would be used to the fullest extent. One of the fundamental roles of hospital pharmacists is to ensure the availability and timely delivery of the safest and most effective therapy. To this end, pharmacists must plan, identify and mitigate the shortage of medicines (limited suppliers of raw materials) and intervene when validating the therapy, mainly in an off-label context, avoiding medication errors, omissions of usual therapies, adverse reactions and contributing to a “precision medicine” in such an unknown scenario.

https://doi.org/10.29315/gm.v7i2.360 51 downloads

10.

Milk production and ingestive behavior of cows grazing on Marandu and Mulato II pastures under rotational stocking
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Demski, Joana Baptista

; Arcaro Junior, Irineu

; Gimenes, Flavia Maria de Andrade

; Toledo, Luciandra Macedo de

; Miranda, Mariana Santos de

; Giacomini, Alessandra Aparecida

; Silva, Gianni Aguiar da

Revista Brasileira de Zootecnia

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2019, Volume 48 elocation e20180231

Abstract: En | Text: En | PDF: En

ABSTRACT The objective of this study was to evaluate milk production and ingestive behavior of Holstein cows and the structural characteristics of Mulato II, a hybrid Brachiaria grass CIAT 36087 (B. ruziziensis × B. decumbens × B. brizantha), and Marandu (Brachiaria brizantha cv. Marandu) pastures under rotational stocking. The experiment was conducted from December 2011 to April 2012 after 10 months of adaptation to the grazing management objectives (25 cm pre-grazing height and 15-20 cm post-grazing height). An area of 4 ha was divided into 28 paddocks: 14 with Mulato II pasture and 14 with Marandu pasture. The treatments consisted of the two grasses and a completely randomized design of the grazing variables with six repetitions each (paddock of evaluation) was used. For the animal variables, a randomized matched pairs design of 20 Holstein cows forming 10 blocks of two animals with similar production each was used. The forage mass or accumulation rate did not differ between grasses. Mulato II pastures had a higher tiller population density (822 tillers m−2) and crude protein content (143.5 g kg−1) than Marandu pastures (636 tillers m−2 and 130.3 g kg−1 crude protein). Cows kept on Mulato II exhibited shorter nighttime grazing activity (234 and 246 min in summer and autumn, respectively) than animals kept on Marandu (273 and 394 min, respectively). The average milk yield during the experimental period was higher for Mulato II (15.3 kg cow−1 day−1) compared with Marandu (14.3 kg cow−1 day−1). Both grasses have potential to be used in milk production systems for the grazing management objectives evaluated.

https://doi.org/10.1590/rbz4820180231 782 downloads

11.

Caregiving Helplessness Questionnaire (CHQ) applied to Portuguese mothers of preschool-aged children: A psychometric study
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Toscano, Carolina

; Baptista, Joana

; Mesquita, Ana

; George, Carol

; Soares, Isabel

Análise Psicológica

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dec 2018, Volume 36 N. 4 Pages 501 - 514

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

O sistema de vinculação da criança é complementado por um sistema, separado e recíproco, de prestação de cuidados parentais, que guia as respostas de proteção do cuidador em relação à criança. Disrupções neste último sistema poderão conduzir a uma prestação de cuidados desorganizada; no entanto, o conhecimento acerca da desorganização da prestação de cuidados permanece incompleta, estando o seu estudo limitado a metodologias dispendiosas. O presente estudo pretendeu analisar as qualidades psicométricas do Caregiving Helplessness Questionnaire (CHQ), uma ferramenta de screening para a desorganização da prestação de cuidados, numa amostra de 200 mães portuguesas de crianças em idade pré-escolar. A análise factorial confirmatória não confirmou a estrutura da versão original do CHQ. Uma solução de cinco fatores verificou-se como sendo a melhor, produzindo cinco escalas conceptualmente correspondentes às principais dimensões da desorganização das relações em idade pré-escolar: Mother Helpless, Mother Frightened, Child Frightened, Child Cheers Mothers e Child Caregiving. O estudo da consistência interna obteve resultados satisfatórios e a validade convergente e discriminante foi confirmada. A validade concorrente também foi estabelecida através de associações significativas entre as escalas do CHQ e variáveis dos domínios materno e da criança que têm sido conceptual e empiricamente associadas com a desorganização. Em conclusão, os resultados suportam a validade do CHQ para mães portuguesas de crianças pré-escolares, como um instrumento de screening promissor desorganização da prestação de cuidados.

The child’s attachment system is complemented by a separate and reciprocal caregiving system in the parent, which guides parents’ protective responses to the child. Disruptions in the caregiving system may lead to disorganized caregiving; however, the study and knowledge of disorganized caregiving is still very incomplete and has been limited to labor-intensive and costly interviews. This study aimed to examine the psychometric qualities of the Caregiving Helplessness Questionnaire (CHQ), a screening tool for disorganized caregiving, on a sample of 200 Portuguese mothers of preschool-aged children. Confirmatory factor analysis did not confirm the structure of the original CHQ version. A five-factor solution was found as a better solution, producing five scales that correspond conceptually to major dimensions of relationship disorganization at preschool-age: Mother Helpless, Mother Frightened, Child Frightened, Child Cheers Mothers, and Child Caregiving. Reliability analysis had satisfactory results and convergent and discriminant validity were confirmed. Concurrent validity was also established by finding significant associations between the CHQ scales with variables of maternal and child domains that have been conceptually and empirically associated with disorganization. In conclusion, results supported the validity of the CHQ for Portuguese mothers of preschoolers, as a promising screening tool for disorganized caregiving.

https://doi.org/10.14417/ap.1544 627 downloads

12.

Being a mother of preterm multiples in the context of socioeconomic disadvantage: perceived stress and psychological symptoms
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Baptista, Joana

; Moutinho, Vanessa

; Mateus, Vera

; Guimarães, Hercília

; Clemente, Fátima

; Almeida, Sara

; Andrade, Maria Agostinha

; Dias, Clara Paz

; Freitas, Alice

; Martins, Carla

; Soares, Isabel

Jornal de Pediatria

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oct 2018, Volume 94 N. 5 Pages 491 - 497

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Objetivo: Examinar as diferenças entre mães de múltiplos prematuros e mães de filhos únicos prematuros a respeito de estresse percebido e sintomas psicológicos maternos e explorar o efeito adverso amplificado putativo da desvantagem socioeconômica. Método: Participaram deste estudo transversal 95 mães de crianças de um ano nascidas prematuras. A coleta de dados foi feita em dois hospitais públicos do norte de Portugal. Para avaliar o estresse diário percebido e os sintomas psicológicos maternos, as mães responderam dois questionários. As mães relataram fatores socioeconômicos, incluindo pobreza familiar, desemprego dos pais e baixo nível de escolaridade, e foram criados dois grupos de desvantagem socioeconômica familiar. Foi calculado um índice de risco médico infantil. Resultados: Os resultados indicaram que as mães de múltiplos prematuros relataram maiores níveis de estresse do que as mães de filhos únicos prematuros. Além disso e especificamente com relação ao funcionamento psicológico, as mães de múltiplos prematuros relataram mais sintomas do que as mães de filhos únicos prematuros, porém apenas quando moravam em um contexto de adversidade socioeconômica. Conclusões: Os resultados deste estudo possuem importantes implicações para a prática. As mães de múltiplos prematuros apresentam maior risco de dificuldades de saúde mental, em comparação a mães de filhos únicos, principalmente quando expostas a adversidades socioeconômicas. O desenvolvimento de programas de intervenção psicossocial e políticas públicas é de importância decisiva ao ajudar as mães de filhos múltiplos a se ajustarem à maternidade.

Abstract Objective: This study aimed to examine the differences between mothers of preterm multiples and mothers of preterm singletons regarding perceived stress and maternal psychological symptoms, and to explore the putative adverse amplified effect of socioeconomic disadvantage. Method: Ninety-five mothers of 1-year-olds born preterm participated in this cross-sectional study. Data collection was carried out in two public hospitals from Northern Portugal. To assess maternal perceived daily stress and psychological symptoms, mothers completed two questionnaires. Mothers reported on socioeconomic factors, including family poverty, parent unemployment, and low education, and two groups of family socioeconomic disadvantage were created. A child medical risk index was calculated. Results: Results indicated that mothers of preterm multiples reported higher levels of stress than mothers of preterm singletons. Moreover, and specifically regarding psychological functioning, mothers of preterm multiples reported more symptoms than mothers of preterm singletons, but only when living in a context of socioeconomic adversity. Conclusions: The results of the present study have important implications for practice. Mothers of preterm multiples are at higher risk to present mental health difficulties, in comparison to mothers of singletons, especially when exposed to socioeconomic adversities. The development of psychosocial intervention programs and public policies are of decisive importance in helping mothers of multiples adjust to parenthood.

https://doi.org/10.1016/j.jped.2017.08.010 916 downloads

13.

Inquérito sobre o conhecimento e aceitação da «síndrome geniturinária da menopausa» pelos ginecologistas portugueses
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Vieira-Baptista, Pedro

; Tavares, Sara

; Lima-Silva, Joana

; Neves, Ana Raquel

; Geraldes, Fernanda

; Águas, Fernanda

Acta Obstétrica e Ginecológica Portuguesa

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jun 2017, Volume 11 N. 2 Pages 92 - 97

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Overview and Aims: The concept of "genitourinary syndrome of menopause" (GUSM), created in 2013, is widely used, despite the lack of studies and validation. This survey intended to evaluate the knowledge, agreement and concerns of Portuguese gynaecologists about it. Study design, population and methods: An online survey was sent to Portuguese gynaecologists (all the members of the Portuguese Society of Gynaecology, personal contacts and specific groups in social networks). Results: Out of 118 completed surveys, 66.1% belonged to specialists and 43.9% to residents. It was reported by 83.9% that they were acquainted with the GUSM, without differences between specialists and residents (85.0% vs. 83.3%, p=1.000). Most (66.7%) use "vaginal atrophy" or "atrophic vaginitis" in their daily practice; GUSM is used by 6.1% and 27.3% use both denominations. Considering "0" to be total disagreement and "10" total agreement, the justifications for the creation of this syndrome were rated as follows: "vaginitis implies infection or inflammation, which is not always the case" 8.1±2.57; "urinary signs and symptoms tend to be overlooked" 6.4±2.96; "atrophy has a negative connotation" 4.7±3.46 and "vagina is not generally a well-accepted term by women and the media" 3.4±3.41. It was considered by 37.9% that it may lead to sub-diagnosis/no diagnosis of sexual dysfunction; of vulvar pathology by 32.6% and of urinary tract pathology by 23.7%. Globally, 77.8% agree with the concept of GUSM, without differences between specialists and residents (80.0% vs. 73.5%, p=0.459); 75.4% consider that they will use it in the future (residents 57.9% vs. specialists 83.3%, p=0.053). Conclusion: Most Portuguese gynaecologists are aware of the concept of GUSM, and intend to use it the future, despite not fully agreeing with the assumptions that led to its creation.

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14.

Prematuridade, Funções Executivas e Qualidade dos Cuidados Parentais: Revisão Sistemática de Literatura
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Doellinger, Patrícia von

; Soares, Isabel

; Sampaio, Adriana

; Mesquita, Ana R.

; Baptista, Joana

Psicologia: Teoria e Pesquisa

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2017, Volume 33 elocation e3321

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Este artigo de revisão visa contextualizar o desenvolvimento das funções executivas (FE) em crianças prematuras, com especial atenção para o efeito dos cuidados parentais. As principais bases eletrônicas foram utilizadas para essa revisão: 31 estudos originais, duas meta-análises, uma meta-síntese e dois artigos de revisão foram identificados. Concluiu-se que as crianças prematuras têm maior risco de disfunção executiva global, sendo a qualidade dos cuidados parentais fundamentais para a modulação das FE, nomeadamente no que concerne às variáveis socioemocionais da interação, como a sensibilidadematerna. Salientam-se ainda as principais limitações dos estudos analisados e apontam-se recomendações para futura investigação sobre os efeitos dos cuidados parentais no desenvolvimento de FE em crianças prematuras.

ABSTRACT This review article aims to contextualize the development of executive functions (EF) in preterm children with special attention to the effects of parental care. The main electronic databases were used for this review: 31 original studies, two meta-analyses, one meta-synthesis and two systematic reviews were identified. The results showed that preterm infants are at risk for global executive dysfunction,and that the quality of parenting impacts the development of EF, mainly in terms of interactive socio-emotional variables, like maternal sensitivity.Finally, the main limitations of the analyzed studies are pointed out, and recommendations of future research about the effects of parental care in the development of EF in preterm children are offered.

https://doi.org/10.1590/0102.3772e3321 3963 downloads

15.

Vaginite inflamatória descamativa
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Lima-Silva, Joana

; Tavares, Sara

; Vieira-Baptista, Pedro

; Beires, Jorge

Acta Obstétrica e Ginecológica Portuguesa

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dec 2016, Volume 10 N. 4 Pages 317 - 325

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Desquamative inflammatory vaginitis (DIV) is a well characterized clinical syndrome of unknown aetiology and pathogenesis. It presents as a diffuse exudative vaginitis, with pain, profuse purulent discharge and epithelial cells exfoliation. Diagnosis is often difficult, since it shares several characteristics with other vulvovaginal inflammatory disorders. Wet mount plays a key role, presenting a marked increase in leukocytes and parabasal cells; pH is elevated (>4.5). The exclusion of other causes of purulent vaginitis is mandatory for the diagnosis. Although the treatment can be a challenge, often requiring maintenance since relapse is common, good results are described with topical clindamycin and corticosteroids.

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