Abstract Klebsiella pneumoniae is a species of Gram-negative bacteria related to a wide range of infections and high rates of drug resistance. The combined use of antibacterial agents is one of the strategies that has been analyzed in recent years as part of the alternatives in the treatment of drug-resistant infections. Recently, the antibacterial activity of of 2-chloro-N-(4-fluoro-3-nitrophenyl)acetamide has been demonstrated against K. pneumoniae, also indicating that this acetamide did not show significant cytotoxic potential in preliminary tests. Thus, it becomes an interesting substance for future studies that explore its antimicrobial capacity, including investigating its association with antibacterial drugs. Based on this, this research aimed to analyze the effects of the association of 2-chloro-N-(4-fluoro-3-nitrophenyl)acetamide (CFA) with ciprofloxacin, cefepime, ceftazidime, meropenem and imipenem against K. pneumoniae strains. The results showed additivity when the substance was combined with ciprofloxacin and cefepime, indifference when associated with ceftazidime and synergistic effect when combined with meropenem and imipenem. Thus, the acetamide was able to optimize the effects of antibacterial drugs, reducing the concentrations necessary to cause bacterial death. These data indicate a potential future clinical use of these combinations, and further studies are needed to analyze this viability.

O presente estudo apresenta as briófitas observadas em forófitos depositados na xiloteca da Universidade do Vale do Rio dos Sinos (UNISINOS). As amostras foram originalmente coletadas no interior das matas ciliares ao longo do Rio Uruguai, entre os municípios de Aratiba, Marcelino Ramos e Mariano Mouro (RS), e Corncórdia e Itá (SC), antes que a área fosse alagada devido à construção da hidrelétrica de Itá. Todas as briófitas nos 187 forófitos foram analisadas, totalizando 1.336 amostras, resultando na observação de 87 espécies, distribuídas em 53 gêneros e 31 famílias. As famílias mais ricas foram Lejeuneaceae (13 espécies), Neckeraceae e Orthotrichaceae (seis espécies).

The present study presents the bryophytes observed in phorophytes kept in the xylothec of the "Universidade do Vale do Rio dos Sinos" (UNISINOS). The samples were formerly collected inside the riparian forests along the Uruguai River, among the municipalities of Aratiba, Marcelino Ramos and Mariano Mouro (RS), and Corncórdia and Itá (SC), before the area was flooded because of the construction of the electric power plan of Itá. All bryophytes at the 187 phorophytes were analysed, totalizing 1,336 samples, resulting in the observation of 87 species, distributed in 53 genera and 31 families. The most rich families were Lejeuneaceae (13 species), Neckeraceae and Orthotrichaceae (six species).