Abstract Introduction Acquired tracheomalacia (ATM) is characterized by a loss of structural strength of the tracheal framework, resulting in airway collapse during breathing. Near half of the patients undergoing prolonged invasive mechanical ventilation will suffer tracheal lesions. Treatment for ATM includes external splinting with rib grafts, prosthetic materials, and tracheal resection. Failure in the use of prosthetic materials has made reconsidering natural origin scaffolds and tissue engineering as a suitable alternative. Objective To restore adequate airway patency in an ovine model with surgicallyinduced ATM employing a tissue-engineered extraluminal tracheal splint (TE-ETS). Methods In the present prospective pilot study, tracheal rings were partially resected to induce airway collapse in 16 Suffolk sheep (Ovis aries). The TE-ETS was developed with autologous mesenchymal-derived chondrocytes and allogenic decellularized tracheal segments and was implanted above debilitated tracheal rings. The animals were followed-up at 8, 12, and 16 weeks and at 1-year postinsertion. Flexible tracheoscopies were performed at each stage. After sacrifice, a histopathological study of the trachea and the splint were performed. Results The TE-ETS prevented airway collapse for 16 weeks and up to 1-year postinsertion. Tracheoscopies revealed a noncollapsing airway during inspiration. Histopathological analyses showed the organization of mesenchymal-derived chondrocytes in lacunae, the proliferation of blood vessels, and recovery of epithelial tissue subjacent to the splint. Splints without autologous cells did not prevent airway collapse. Conclusion It is possible to treat acquired tracheomalacia with TE-ETS without further surgical removal since it undergoes physiological degradation. The present study supports the development of tissue-engineered tracheal substitutes for airway disease.

RESUMEN Objetivo: Determinar las características y factores asociados a la percepción de maltrato en internos de medicina del Perú. Materiales y métodos : Estudio multicéntrico, transversal y analítico. Se encuestaron a internos de medicina de dieciocho hospitales del Perú. Se aplicó una encuesta entre marzo y abril del 2016 que incluían características sociodemográficas y una escala que media la percepción de maltrato psicológico, físico y sexual. Se realizaron modelos lineales generalizados y se estimaron razones de prevalencia crudas y ajustadas (RPa) con intervalos de confianza al 95%. Resultados : Participaron 418 internos de medicina. El maltrato psicológico, físico y sexual percibido fue de 91,9%; 55,5% y 34%, respectivamente. Los factores asociados con el maltrato psicológico fueron proceder de una universidad privada (RPa:1,07; IC95%:1,01- 1,13), respecto al maltrato físico fueron la edad (RPa: 1,08; IC95%: 1,05-1,12), realizar internado en un hospital de la selva (RPa: 1,27; IC95%: 1,03-1,56) y en un hospital del Seguro Social (RPa:0,66; IC95%:0,44-0,94) y para el maltrato sexual el ser mujer (RPa:1,52; IC95%:1,15-2,01). Conclusiones : Existe una alta percepción de maltrato reportado por los internos de medicina siendo el psicológico el más frecuente. Existen diferencias en la percepción de maltrato psicológico y físico según el tipo de financiamiento de la universidad de procedencia y del hospital donde se realiza el internado. Una alta frecuencia de maltrato sexual fue reportada por mujeres luego de los tres primeros meses del internado hospitalario.

ABSTRACT Objective: To determine the characteristics and factors associated with the perception of abuse in medicine interns of Peru. Material and Methods : This is a cross-sectional multicenter and analytical study. Medicine interns from eighteen Peruvian hospitals were interviewed. A survey was administered between March and April 2016, which included socio-demographic characteristics and a scale measuring psychological and physical abuse, as well as sexual harassment perception. Generalized linear models were used and crude and adjusted prevalence rates (aPR) were estimated, with 95% confidence intervals (CI). Results: 418 medical interns participated in the study. Psychological and physical abuses were perceived by 91,9% and 55,5% of the studied population. Sexual harassment was perceived by 34% of all interviewed interns. Associated factors with psychological abuse were studied in a private university (aPR: 1.07; 95% CI: 1.01-1.13). Factors associated with physical abuse were age (aPR: 1.08; 95% IC: 1.05-1.12), performing internship in an Amazonian area hospital (aPR: 1,27; 95% CI: 1,03-1,56), and in a Social Security Hospital (aPR: 0,66; 95% CI: 0,44-0,94); and for sexual harassment, being female was the main associated factor (aPR: 1,52; 95% CI: 1,15-2,01). Conclusions: There is a high perception of abuse experienced by medicine interns, being psychological abuse the most frequent condition. There are some differences in the perception of psychological and physical abuse, according to the medical school the interns come from, as well as with respect to the healthcare facility where internship is performed. A high frequency of sexual harassment was reported by female interns after three months of having started their training period.

Runa soncco, a Quechua term for “Indian heart”, is the title of a magazine published between 1935 and 1948, which articles reveal the intention to integrate the Andean culture with Western public health on-site. It also turned into a key tool for the dissemination of the sanitation and education message and the indigenous movement led by Dr. Manuel Núñez Butrón, one of the first experiences in promotional preventive care in Peru and in the world - a pioneer of what four decades later would be called “primary health care”.

Runa soncco palabra quechua que significa “corazón de indio” es el título de una revista publicada del año 1935 al 1948, cuyos artículos reflejan el deseo por integrar la cultura andina con la salud pública occidental, desde el mismo campo de acción. Esta publicación logró situarse como una herramienta fundamental en la difusión del mensaje sanitario y de educación del movimiento indigenista liderado por el médico Manuel Núñez Butrón. Constituye una de las primeras experiencias en atención preventivo-promocional en el Perú y el mundo, anticipándose a lo que cuatro décadas más tarde se denominaría “atención primaria de la salud”.

Runa soncco, a Quechua term for “Indian heart”, is the title of a magazine published between 1935 and 1948, which articles reveal the intention to integrate the Andean culture with Western public health on-site. It also turned into a key tool for the dissemination of the sanitation and education message and the indigenous movement led by Dr. Manuel Núñez Butrón, one of the first experiences in promotional preventive care in Peru and in the world - a pioneer of what four decades later would be called “primary health care”.

Runa soncco palabra quechua que significa “corazón de indio” es el título de una revista publicada del año 1935 al 1948, cuyos artículos reflejan el deseo por integrar la cultura andina con la salud pública occidental, desde el mismo campo de acción. Esta publicación logró situarse como una herramienta fundamental en la difusión del mensaje sanitario y de educación del movimiento indigenista liderado por el médico Manuel Núñez Butrón. Constituye una de las primeras experiencias en atención preventivo-promocional en el Perú y el mundo, anticipándose a lo que cuatro décadas más tarde se denominaría “atención primaria de la salud”.

We report an adult male who was admitted to hospital for emergency after being shot by a firearm, presenting a bullet entry hole in the upper lip of the mouth, finding no outlet, radiological examination shows shrapnel oral cavity and the presence of a foreign body in the digestive tract, which migrates to the rectum to be expelled for five days, being compatible with the projectile, after clinical response to medical management

Reportamos el caso de un hombre adulto que ingresa al hospital por emergencia luego de haber recibido un disparo por arma de fuego, presentando un orificio de entrada de proyectil en labio superior de la boca, no evidenciándose orificio de salida, el examen radiológico muestra esquirlas en cavidad oral así como la presencia de un cuerpo extraño en tracto digestivo, que migra hasta ser expulsado por el recto cinco días después, siendo compatible con el proyectil, paciente evolucionó favorablemente posterior al manejo médico.

We performed a bibliometric study, searching for articles published by authors affiliated Ica, in indexed scientific journals, with the aim to know the biomedical scientific production in this Peruvian province during the decade from 1998 to 2007. We found 37 papers, most research in the public health area, ten of which were published in journals out of circulation. The most common affiliation of the authors is the Faculty of Sciences of the Universidad Nacional San Luis Gonzaga (46.9%), while the faculties of medicine and nursing are those that occur less frequently (both 2.7%). It should enhance the scientific output of institutions in health sciences in the province of Ica, requiring more training and motivation to become a publishing culture in their students and professionals.

Se realizó un estudio bibliométrico, buscando los artículos publicados por autores con afiliación Ica, en revistas científicas indizadas, con el objetivo de conocer la producción científica biomédica en dicha provincia peruana, durante el decenio 1998 - 2007. Se encontró 37 artículos, en su mayoría investigaciones en el área de salud pública, diez de éstas fueron publicadas en revistas fuera de circulación. La filiación más frecuente de los autores es la Facultad de Ciencias de la Universidad Nacional San Luis Gonzaga (46,9%), mientras que las Facultades de Medicina y Enfermería son las que se presentan en menor frecuencia (ambas con 2,7%). Se debe potenciar la producción científica de las instituciones en ciencias de la salud de la provincia de Ica, siendo necesaria una mayor capacitación y motivación orientada a formar una cultura de publicación en sus estudiantes y profesionales.