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Abstract Anthropogenic interventions have had a compromising effect on environmental health, intensifying the degradation of ecosystems, and the quantity of chemical pollutants released into nature. Therefore, research areas within the scope of environmental assessments and monitoring such as ecotoxicology have contributed to the determination of the toxic potential of contaminants. A small cyprinid known as the zebrafish (Danio rerio), the use of which has exponentially grown, is an alternative vertebrate model for scientific research, mainly in the assessment of environmental risks. The species exhibits several advantages for breeding in a laboratory, in addition to presenting multi-biomarkers of environmental toxicity. Thus, this review aims to present the main characteristics and advantages of working with this species, as well as show studies related to ecotoxicology involving biomarkers of toxicity in zebrafish. The results show a progressive trend towards employing the species in environmental risk analyses, it is an increasingly recommended species in the assessment of the toxicity level of a range of chemical pollutants. The development of future technologies must contribute to scientific advancement, rendering the potential application of this model organism an even more widespread one, which will certainly help in bridging knowledge gaps in various areas of study.

https://doi.org/10.1590/1678-4324-2024220968

Reply to the letter regarding the article entitled: “Access to rehabilitation after stroke in Brazil (AReA study): multicenter study protocol” entitled Access AReA study) protocol
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Cacho, Roberta de Oliveira

; Moro, Carla Heloisa Cabral

; Bazan, Rodrigo

; Guarda, Suzete Nascimento Farias da

; Pinto, Elen Beatriz

; Andrade, Suellen Mary Marinho dos Santos

; Valler, Lenise

; Almeida, Kelson James

; Ribeiro, Tatiana Souza

; Jucá, Renata Viana Brígido de Moura

; Minelli, Cesar

; Piemonte, Maria Elisa Pimentel

; Paschoal, Eric Homero Albuquerque

; Pedatella, Marco Túlio Araújo

; Pontes-Neto, Octávio Marques

; Fontana, Ana Paula

; Pagnussat, Aline de Souza

; Conforto, Adriana Bastos

Arquivos de Neuro-Psiquiatria

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jul 2023, Volume 81 N. 7 Pages 703 - 704

Abstract: En | Text: En | PDF: En

https://doi.org/10.1055/s-0043-1771266

Excess of deaths during COVID-19 pandemic in Mato Grosso, Brazil
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Oliveira, Ligia Regina de

; Muraro, Ana Paula

; Cecconello, Moiseis dos Santos

; Lalucci, Mauro Citro

; Andrade, Amanda Cristina de Souza

Ciência & Saúde Coletiva

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2023, Volume 28 N. 12 Pages 3599 - 3608

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo O objetivo deste artigo é estimar o excesso de óbitos nos anos de 2020 e 2021 no estado de Mato Grosso, na capital do estado e no interior, segundo sexo e faixa etária. Os dados foram extraídos do site do DATASUS/Ministério da Saúde para o período de 2015 a 2020 e do site da Secretaria de Estado da Saúde - Sistema Data Warehouse (DW) para 2021. Óbitos não fetais por causas naturais de residentes no Mato Grosso foram analisados e as análises foram divididas em interior e capital do estado (Cuiabá). As variáveis selecionadas foram: faixa etária, sexo, mês de ocorrência e causa básica do óbito. O excesso de mortalidade foi calculado usando ajustes generalizados do modelo aditivo quase-Poisson com correção para superdispersão. Identificou-se um excesso de 30% de óbitos em 2020, com a capital do estado registrando a maior estimativa, nas faixas etárias mais avançadas, e entre os meses de julho e setembro. Em 2021, o número esperado de óbitos foi de 57% superior, sendo o dobro nas faixas etárias mais jovens do interior do estado. O estudo mostrou diferentes perfis demográficos de excesso de óbitos nos anos de 2020 e 2021 durante a pandemia de COVID-19 e padrões distintos entre interior e capital do estado, sugerindo desigualdades que podem ter impactado em diferentes riscos.

Abstract This article aims to estimate the excess of deaths in the years 2020 and 2021 in Mato Grosso state, in the state capital and in the countryside, according to gender and age group. Data was extracted from DATASUS/Ministry of Health website for the period from 2015 to 2020 and from the website of the State Department of Health - Data Warehouse System (DW) for 2021. Non-fetal deaths by natural causes of residents in Mato Grosso were analyzed and the analyses were broken down into countryside and state capital (Cuiabá). The variables selected were age group, gender, month of occurrence, and underlying cause of death. Excess mortality was calculated using generalized additive quasi-Poisson model adjustments with correction for overdispersion. A 30% excess of deaths was identified in 2020, with the state capital recording the highest estimate, in older age groups, and between the months of July and September. In 2021, the expected number of deaths was 57% higher, with the double in the younger age groups in the countryside. The study showed different demographic profiles of excess deaths in the years 2020 and 2021 during COVID-19 pandemic and distinct patterns between countryside and state capital, suggesting inequalities that may have caused impact on different risks.

https://doi.org/10.1590/1413-812320232812.13002022

Pressure injury prevention in older people: construction and validation of an instrument for caregivers
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Matos, Suellen Duarte de Oliveira

; Souza, Ana Paula Marques de Andrade

; Abreu, Margarida da Silva Neves de

; Gomes, Anne Carolinne Marie dos Santos

; Oliveira, Jacira dos Santos

; Silva, Mirian Alves da

; Soares, Maria Júlia Guimarães Oliveira

; Oliveira, Simone Helena dos Santos

Revista Brasileira de Enfermagem

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2023, Volume 76 N. 1 elocation e20210930

Abstract: En Es Pt | Text: En Es Pt | PDF: En | PDF: Es | PDF: Pt

ABSTRACT Objectives: to construct and validate an instrument to assess the knowledge, attitudes, and practices related to pressure injury prevention among caregivers of institutionalized older people. Methods: this is a three-stage methodological study that consisted of instrument construction, analysis by experts, and semantic and appearance analysis, with 78 participants, observing the validation process steps for psychometric instruments in the criteria of clarity and relevance. Results: in the Delphi I round, the validity index of the general content in the clarity criterion was 0.66, in relevance 0.85, and the Kappa value was >0.76. In Delphi II, clarity was 0.95, relevance 1.00, and the Kappa value was >0.97. Conclusions: this is a valid instrument in terms of content and appearance, which allows further analysis of its reliability for the measurement of the constructs for which it is intended. Therefore, it can be considered a tool for care management in pressure injury prevention.

RESUMEN Objetivos: construir y validar un instrumento pera evaluación del conocimiento, actitud y práctica relacionado a la prevención de lesiones por presión entre cuidadores de ancianos institucionalizados. Métodos: estudio metodológico realizado en tres fases: construcción del instrumento, análisis de los evaluadores y análisis semántico y de apariencia, con 78 participantes siguiendo las etapas del proceso de validación de instrumentos psicométricos para los criterios claridad y pertinencia. Resultados: en la ronda Delphi I el índice de validez de contenido general del criterio “claridad” fue de 0,66, “pertinencia” 0,85, y valor de Kappa > 0,76. En Delphi II, el criterio de “claridad” fue 0,95, “pertinencia” 1,00 y valor de Kappa > 0,97. Conclusiones: se tiene un instrumento válido respecto de contenidos y apariencia, para continuar analizando su confiabilidad para medir los constructos a los cuales se propone, para que sirva como herramienta de gestión del cuidado en la prevención de lesiones por presión.

RESUMO Objetivos: construir e validar instrumento relacionado à prevenção de lesão por pressão para avaliação do conhecimento, da atitude e da prática de cuidadores de idosos institucionalizados. Métodos: estudo metodológico realizado em três fases: construção do instrumento, análise dos juízes e análise semântica e aparente, com 78 participantes, seguindo as etapas do processo de validação de instrumentos psicométricos para os critérios clareza e pertinência. Resultados: na rodada Delphi I, o índice de validade de conteúdo global do critério “clareza” foi de 0,66, “pertinência” 0,85 e valor de Kappa > 0,76. Em Delphi II, o critério de “clareza” foi de 0,95, “pertinência” 1,00 e valor de Kappa > 0,97. Conclusões: dispõe-se de instrumento válido quanto a conteúdo e aparência para dar seguimento à análise da sua confiabilidade em medir os construtos aos quais se propõe, para que possa servir de ferramenta para gestão do cuidado na prevenção de lesão por pressão.

https://doi.org/10.1590/0034-7167-2021-0930

A case of canine visceral leishmaniasis of unknown origin in Curitiba (state of Paraná, Brazil) treated successfully with miltefosine
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Gonçalves, Gustavo

; Campos, Monique Paiva

; Tirado, Thais Cristina

; Negrão, Dayane Domingos

; Silva, Gabriela Mayoral Pedroso da

; Poleto, Ana Paula Coninck Mafra

; Hartin, Tatianna Paula

; Silva, Juliana Batista Andrade

; Castilhos, Marilia de Melo Santos de

; Figueiredo, Fabiano Borges

Revista Brasileira de Parasitologia Veterinária

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2023, Volume 32 N. 2 elocation e001123

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

Abstract There are no records of autochthonous cases of canine visceral leishmaniasis in the city of Curitiba, Paraná state, Brazil. In 2020, a male French bulldog (CW01), approximately 2 years old was taken by its owners to a private veterinarian clinic. The suspicion of CVL was confirmed by means of a serology test (ELISA/IFAT reagent), rapid chromatographic immunoassay (DPP®) (ELISA - Biomanguinhos®), parasitological culture and quantitative polymerase chain reaction (qPCR). The animal routinely frequented parks in Curitiba and was taken on several trips to the municipalities of Bombinhas and Balneário Camboriú (Santa Catarina) and to Matinhos (Paraná) where CVL had not previously been reported. Treatment was initiated orally with Milteforan™ which resulted in a significant reduction in the parasitic load. The suspicion of autochthony was investigated through entomological research. A total of 10 traps were installed, one at the animal’s home, seven in adjacent city blocks and two in a forest edge. No sandflies were trapped in the dog’s home and adjacent houses. The traps in the forest edge caught one Migonemyia migonei female and five Brumptomyia spp. females. This case serves as a warning of the possible introduction of CVL in the city of Curitiba.

Resumo Não há registros de casos autóctones de leishmaniose visceral canina (LVC) no município de Curitiba, Paraná, Brasil. Em 2020, um "bulldog" francês macho (CW01), com aproximadamente 2 anos de idade, foi levado por seus donos a uma clínica veterinária particular. A suspeita de LVC foi confirmada por meio de teste sorológico (reagente ELISA/IFAT), imunoensaio cromatográfico rápido (DPP®) (ELISA - Biomanguinhos®), cultura parasitológica e reação quantitativa em cadeia da polimerase (qPCR). O animal frequentava, rotineiramente, parques de Curitiba e foi levado em diversas viagens para Bombinhas e Balneário Camboriú (Santa Catarina) e para Matinhos (Paraná), onde a LVC não havia sido relatada anteriormente. O tratamento foi iniciado por via oral com Milteforan™ (Virbac) o que resultou em redução significativa da carga parasitária. A suspeita de autóctone foi investigada por meio de pesquisa entomológica. Foram instaladas 10 armadilhas, uma na casa do animal, sete em quarteirões adjacentes e duas na borda da mata. Nenhum inseto foi capturado na casa do proprietário do animal e nas casas adjacentes. As armadilhas na borda da mata capturaram uma fêmea de Migonemyia migonei e cinco Brumptomyia spp. fêmeas. Este caso serve de alerta para a possível introdução da LVC na cidade de Curitiba.

https://doi.org/10.1590/s1984-29612023026

The impact of post-COVID multicomponent rehabilitation
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Oliveira, Karla Cybele Vieira de

; Ferreira, Ana Paula de Lima

; Silva, Diana de Andrade

; Monteiro, Janaína dos Santos

; Silva, Kennedy Victor

; Lucena, Larissa Coutinho de

; Araújo, Maria das Graças Rodrigues de

Fisioterapia em Movimento

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2023, Volume 36 elocation e36112

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

Abstract Introduction Post-COVID-19 syndrome is characterized by chronic fatigue and myalgia, among other symptoms, which can limit activities of daily living. Physical therapy protocols with multicomponent exercises combine strength, resistance, balance and gait, producing sig-nificant improvements in functional mobility. Objective Evaluate whether multicomponent rehabilitation is effective in improving functional mobility and quality of life in individuals with post-COVID-19 syndrome. Methods Randomized controlled trial with 59 volunteers, divided into an intervention (IG) and control group (CG), all of whom underwent initial assessment (T0). The IG performed 24 sessions over 12 weeks and the CG did not undergo training. Functional mobility was analyzed using the 6-minute walk test (6MWT) and the Berg balance scale, while the SF-36 questionnaire assessed quality of life. Results In the 6MWT, the IG covered 464.40 + 81.26 meters (T0) and 518.60 + 82.68 meters (T4). The IG Berg scale scores were 48.00 + 4.00 (T0) and 51.90 + 4.26 (T4). In terms of quality of life, the IG obtained mean scores of 96.26 + 10.14 (T0) and 102.60 + 5.53 (T4). None of these measures was statistically significant. Conclusion Individuals who underwent the multicomponent phys-iotherapy protocol showed statistically nonsignificant increases in the variables studied.

Resumo Introdução A síndrome pós-COVID-19 caracteriza-se por fadiga crônica, mialgia, entre outros sintomas que podem causar limitações na realização das atividades de vida diária. Protocolos de fisioterapia com exercício de multicomponentes combinam força, resistência, equi-líbrio e marcha, e produzem melhorias significativas na mobilidade funcional. Objetivo Avaliar se a reabilitação de multicomponentes é eficaz em promover melhora na mobilidade funcional e qualidade de vida em indivíduos com síndrome pós-COVID-19. Métodos Ensaio clínico randomizado, controlado, realizado com 59 voluntários, divididos em grupo intervenção (GI) e grupo controle (GC). Todos fizeram avaliação inicial (T0); GI realizou 24 sessões durante 12 semanas e GC não realizou treinamento. A análise da mobilidade funcional foi realizada através do teste de caminhada de 6 minutos (TC6m) e da escala de equilíbrio de Berg. O questionário SF-36 avaliou a qualidade de vida. Resultados A distância percorrida no TC6m pelo GI foi de 464,40 + 81,26 metros (T0) e de 518,60 + 82,68 metros (T4). A pontuação na escala de Berg do GI foi de 48,00 + 4,00 (T0) e de 51,90 + 4,26 (T4). Na qualidade de vida, GI apresentou escore com média de 96,26 + 10,14 (T0) e 102,60 + 5,53 (T4). Nenhuma destas medidas foram estatisticamente significantes. Conclusão Os indivíduos que foram submetidos ao protocolo fisioterapêutico de multicomponentes apresentaram incrementos nas variáveis estudadas sem significância estatística.

https://doi.org/10.1590/fm.2023.36112

Contribution of public oral pathology services to the diagnosis of oral and oropharyngeal cancer in Brazil
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LOUREDO, Brendo Vinicius Rodrigues

; CURADO, Maria Paula

; PENAFORT, Paulo Victor Mendes

; DE ARRUDA, José Alcides Almeida

; ABREU, Lucas Guimarães

; MESQUITA, Ricardo Alves

; PINTO-JÚNIOR, Décio dos Santos

; ABRAHÃO, Aline Corrêa

; ANDRADE, Bruno Augusto Benevenuto de

; AGOSTINI, Michelle

; MORAES, Renata Mendonça

; ANBINDER, Ana Lia

; DOURADO, Pedro Henrique Silva

; SANTOS, Teresa Cristina Ribeiro Bartholomeu dos

; PIRES, Fábio Ramoa

; BORDIGNON, Natalia Cristina Trentin

; GONDAK, Rogério Oliveira

; DE OLIVEIRA, Marcia Gaiger

; CARRARD, Vinicius Coelho

; MARTINS, Manoela Domingues

; SOUSA-NETO, Sebastião Silvério

; ARANTES, Diego Antônio Costa

; MENDONÇA, Elismauro Francisco

; CIESLAK-SANCHES, Silvia Roberta

; ANTUNES, Daniella Moraes

; AMARAL-SILVA, Gleyson Kleber do

; MANIERI, Patricia Rubia

; RAMALHO, Luciana Maria Pedreira

; DOS SANTOS, Jean Nunes

; LEONEL, Augusto César Leal da Silva

; PEREZ, Danyel Elias da Cruz

; VERHEUL, Hannah Carmem Carlos Ribeiro Silva

; BARROSO, Keila Martha Amorim

; RODRIGUES, Flávia Luiza Santos

; GONZAGA, Amanda Katarinny Goes

; FERNANDES, Romana Renery

; DE SOUZA, Lélia Batista

; SOUZA, Lucas Lacerda de

; PONTES, Flávia Sirotheau Corrêa

; PONTES, Hélder Antônio Rebelo

; SILVA, Caroline Alfaia

; CÂMARA, Jeconias

; LIBÓRIO-KIMURA, Tatiana Nayara

; SANTOS-SILVA, Alan Roger

; LOPES, Márcio Ajudarte

; ALMEIDA, Oslei Paes de

; ROMAÑACH, Mário José

; VARGAS, Pablo Agustin

Brazilian Oral Research

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2023, Volume 37 elocation e126

Abstract: En | Text: En | PDF: En

Abstract This study aimed to evaluate the contribution of oral and maxillofacial pathology laboratories (OMPLs) in Brazilian public universities to the diagnosis of lip, oral cavity, and oropharyngeal squamous cell carcinoma (SCC). A cross-sectional study was performed using biopsy records from a consortium of sixteen public OMPLs from all regions of Brazil (North, Northeast, Central-West, Southeast, and South). Clinical and demographic data of patients diagnosed with lip, oral cavity, and oropharyngeal SCC between 2010 and 2019 were collected from the patients’ histopathological records. Of the 120,010 oral and maxillofacial biopsies (2010-2019), 6.9% (8,321 cases) were diagnosed as lip (0.8%, 951 cases), oral cavity (4.9%, 5,971 cases), and oropharyngeal (1.2%, 1,399 cases) SCCs. Most cases were from Brazil’s Southeast (64.5%), where six of the OMPLs analyzed are located. The predominant profile of patients with lip and oral cavity SCC was Caucasian men, with a mean age over 60 years, low schooling level, and a previous history of heavy tobacco consumption. In the oropharyngeal group, the majority were non-Caucasian men, with a mean age under 60 years, had a low education level, and were former/current tobacco and alcohol users. According to data from the Brazilian National Cancer Institute, approximately 9.9% of the total lip, oral cavity, and oropharyngeal SCCs reported over the last decade in Brazil may have been diagnosed at the OMPLs included in the current study. Therefore, this data confirms the contribution of public OMPLs with respect to the important diagnostic support they provide to the oral healthcare services extended by the Brazilian Public Health System.

https://doi.org/10.1590/1807-3107bor-2023.vol37.0126

Excess of deaths during COVID-19 pandemic in Mato Grosso, Brazil
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Oliveira, Ligia Regina de

; Muraro, Ana Paula

; Cecconello, Moiseis dos Santos

; Lalucci, Mauro Citro

; Andrade, Amanda Cristina de Souza

Ciência & Saúde Coletiva

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2023, Volume 28 N. 12 Pages 3599 - 3608

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

https://doi.org/10.1590/1413-812320232812.13002022

Access to rehabilitation after stroke in Brazil (AReA study): multicenter study protocol
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Cacho, Roberta de Oliveira

; Moro, Carla Heloisa Cabral

; Bazan, Rodrigo

; Guarda, Suzete Nascimento Farias da

; Pinto, Elen Beatriz

; Andrade, Suellen Mary Marinho dos Santos

; Valler, Lenise

; Almeida, Kelson James

; Ribeiro, Tatiana Souza

; Jucá, Renata Viana Brígido de Moura

; Minelli, Cesar

; Piemonte, Maria Elisa Pimentel

; Paschoal, Eric Homero Albuquerque

; Pedatella, Marco Túlio Araújo

; Pontes Neto, Octávio Marques

; Fontana, Ana Paula

; Pagnussat, Aline de Souza

; Conforto, Adriana Bastos

Arquivos de Neuro-Psiquiatria

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oct 2022, Volume 80 N. 10 Pages 1067 - 1074

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

Abstract Background Most of the Brazilian population relies on public healthcare and stroke is a major cause of disability in this country of continental dimensions. There is limited information about access to rehabilitation after stroke in Brazil. Objective To provide comprehensive information about Access to Rehabilitation After discharge from public hospitals in Brazil (AReA study), up to 6 months after stroke. Methods The present study intends to collect information from 17 public health centers in 16 Brazilian cities in the 5 macroregions of the country. Each center will include 36 participants (n = 612). The inclusion criteria are: age ≥ 18 years old; ischemic or hemorrhagic stroke, from 6 months to 1 year prior to the interview; admission to a public hospital in the acute phase after stroke; any neurological impairment poststroke; patient or caregiver able to provide informed consent and answer the survey. Patients can only be recruited in public neurology or internal medicine outpatient clinics. Outcomes will be assessed by a standard questionnaire about rehabilitation referrals, the rehabilitation program (current status, duration in months, number of sessions per week) and instructions received. In addition, patients will be asked about preferences for locations of rehabilitation (hospitals, clinics, or at home). Trial Status The study is ongoing. Recruitment started on January 31st, 2020 and is planned to continue until June 2022. Conclusion The AReA study will fill a gap in knowledge about access to stroke rehabilitation in the public health system in different Brazilian regions.

Resumo Antecedentes Grande parte da população brasileira depende de saúde pública e o acidente vascular cerebral (AVC) é uma das principais causas de incapacidade neste país de dimensões continentais. As informações sobre o acesso à reabilitação após AVC em instalações públicas no Brasil são limitadas. Objetivo Fornecer informações abrangentes sobre o Acesso à Reabilitação pós-AVC (estudo AReA) nos primeiros 6 meses após a alta hospitalar da rede pública. Métodos Serão coletadas informações de 17 centros de saúde públicos em 16 cidades brasileiras das cinco macrorregiões do país. Cada centro incluirá 36 participantes (n = 612). Os critérios de inclusão são: idade ≥ 18 anos; AVC isquêmico ou hemorrágico, com tempo de lesão entre 6 meses e 1 ano; admissão em hospital público na fase aguda; qualquer comprometimento neurológico pós-AVC; paciente ou cuidador capaz de fornecer consentimento informado e responder à pesquisa. Os pacientes só podem ser recrutados em ambulatórios públicos de neurologia ou medicina interna. Os resultados serão avaliados por um questionário padrão sobre encaminhamentos de reabilitação, o programa de reabilitação (estado atual, duração em meses, número de sessões por semana) e instruções recebidas. Além disso, os pacientes serão questionados sobre as preferências de locais de reabilitação (hospitais, clínicas ou casa). Status do estudo O estudo está em andamento. O recrutamento começou em 31 de janeiro de 2020 e está previsto para continuar até junho de 2022. Conclusão O estudo AReA preencherá uma lacuna no conhecimento sobre o acesso à reabilitação para AVC no sistema público de saúde em diferentes regiões brasileiras.

https://doi.org/10.1055/s-0042-1758558

10.

Longitudinal whole-brain analysis of multi-subject diffusion data in diffuse axonal injury
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Grassi, Daphine Centola

; Zaninotto, Ana Luiza

; Feltrin, Fabrício Stewan

; Macruz, Fabíola Bezerra de Carvalho

; Otaduy, Maria Concepción García

; Leite, Claudia da Costa

; Guirado, Vinicius Monteiro de Paula

; Paiva, Wellingson Silva

; Andrade, Celi Santos

Arquivos de Neuro-Psiquiatria

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mar 2022, Volume 80 N. 3 Pages 280 - 288

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Antecedentes: A lesão axonial difusa ocorre em traumas com alta energia de aceleração e desaceleração, determinando desorganização da microestrutura cerebral, levando a algum déficit. A escala de Glasgow Estendida (GOS-E) é indicada na avaliação clínica das vítimas de trauma cranioencefalico. Imagens por tensor de difusão (DTI) estudam a microestrutura cerebral a partir da difusão das moléculas de água. Objetivo: Investigar a microestrutura cerebral no primeiro ano após trauma, avaliar clinicamente os pacientes e testar para correlações entre estes resultados. Métodos: 20 vítimas de TCE moderado e grave foram avaliados 2 meses e 1 ano depois do trauma. O processamento foi feito usando o software FMRIB (FSL) e a análise estatística foi feita com tract-based spatial statistics software para extrair os parâmetros de DTI. Calculamos a diferença da média entre as duas observações de cada sujeito e fizemos um teste-t para uma amostra e threshold-free cluster enhancement. Realizamos correções para múltiplas comparações e determinamos o valor de p < 0.05 como significativo. Um ano após o trauma, a avaliação clínica foi feita usando a GOS-E. Testamos para associações entre os resultados clínicos e os valores médios de FA dos clusters. Resultados: Os clusters significativos foram identificados usando o atlas JHU WM. Observamos aumento de FA predominantemente no hemisfério cerebral direito e cerebelar à esquerda e também extensas áreas de aumento nos demais parâmetros de DTI. A recuperação dos pacientes foi satisfatória. Conclusões: Não encontramos associações entre os resultados, no entanto alguma associação pequena a moderada não pode ser excluída.

ABSTRACT Background: Diffuse axonal injury occurs with high acceleration and deceleration forces in traumatic brain injury (TBI). This lesion leads to disarrangement of the neuronal network, which can result in some degree of deficiency. The Extended Glasgow Outcome Scale (GOS-E) is the primary outcome instrument for the evaluation of TBI victims. Diffusion tensor imaging (DTI) assesses white matter (WM) microstructure based on the displacement distribution of water molecules. Objective: To investigate WM microstructure within the first year after TBI using DTI, the patient’s clinical outcomes, and associations. Methods: We scanned 20 moderate and severe TBI victims at 2 months and 1 year after the event. Imaging processing was done with the FMRIB software library; we used the tract-based spatial statistics software yielding fractional anisotropy (FA), mean diffusivity (MD), axial diffusivity (AD), and radial diffusivity (RD) for statistical analyses. We computed the average difference between the two measures across subjects and performed a one-sample t-test and threshold-free cluster enhancement, using a corrected p-value < 0.05. Clinical outcomes were evaluated with the GOS-E. We tested for associations between outcome measures and significant mean FA clusters. Results: Significant clusters of altered FA were identified anatomically using the JHU WM atlas. We found increasing spotted areas of FA with time in the right brain hemisphere and left cerebellum. Extensive regions of increased MD, RD, and AD were observed. Patients presented an excellent overall recovery. Conclusions: There were no associations between FA and outcome scores, but we cannot exclude the existence of a small to moderate association.

https://doi.org/10.1590/0004-282x-anp-2020-0595

11.

Aspects of trauma related to violence, accidents and falls before and during the COVID-19 pandemic
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Fermandes, Paulo Cesar Rozental

; Ilias, Elias Elias Jirjoss

; Ribeiro, Ana Paula

; Garcia, Diego Ferreira Andrade

; Pereira, Thales Felipe dos Santos

; Freitas, Letícia Dantas Marques de

; Leite, Isabelle Sacchi

; Nascimento, Lucas Netto

; França, Carolina Nunes

; Juliano, Yara

; Novo, Neil Ferreira

Medicina Legal de Costa Rica

Journal Metrics
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mar 2022, Volume 39 N. 1 Pages 81 - 97

Abstract: Es En | Text: Es En | PDF: Es | PDF: En

Resumen Introducción: El trauma es la segunda causa de mortalidad y la sexta de hospitalización en el país, siendo la violencia, los accidentes y las caídas las más prevalentes. Sin embargo, el país está experimentando reflejos de una pandemia de COVID-19, junto a una falta de estudios sobre el trauma, así como sobre la atención clínica. Objetivo: Analizar las características clínicas y epidemiológicas del trauma junto a la violencia, accidentes y caídas entre los años 2019, 2020 y 2021, considerados antes y durante la pandemia COVID-19. Materiales y métodos: Estudio de cohorte retrospectivo, con adultos de 25 a 55 años, que sufrieron trauma relacionado con violencia, caídas y otros accidentes, en el período comprendido entre marzo y junio de 2019, 2020 y 2021, en la ciudad de São Paulo. Las encuestas de datos fueron realizadas por el sistema TABNET, por el Departamento Municipal de Salud. Dentro de este sistema, la búsqueda se realizó a través del Sistema de Información para la Vigilancia de Accidentes, de la Coordinación de Vigilancia en Salud, en el cual las situaciones de violencia fueron notificadas y registradas por el Sistema Nacional de Información de Enfermedades Notificables. Posteriormente, se accedió al Sistema de Información de Vigilancia de Violencia y Accidentes, con enfoque en notificaciones y registro de caídas y otros accidentes. Resultados: El trauma siguió siendo más prevalente para los hombres, con educación primaria completa y raza predominantemente entre blancos y morenos. Al analizar los diferentes tipos de violencia: física, tortura y sexual, hubo mayores porcentajes de prevalencia durante el año 2019, período prepandémico de COVID-19, a excepción de la violencia psicológica / moral, que fue mayor en 2021. Nótese que los diferentes mecanismos de violencia fueron significativamente más prevalentes en 2019, así como las diferentes causas de violencia, caídas y traumatismos automovilísticos que involucran a peatones, ocupantes, conductores y pasajeros. La atención ambulatoria confirmó la tendencia de superioridad en el período prepandémico, sin embargo, la atención hospitalaria de emergencia mostró un mayor número de solicitudes en 2020 y 2021. Conclusión: Los traumas de violencia, accidentes y caídas son más prepandémico en comparación con el período durante la pandemia COVID-19; así como la búsqueda de asistencia sanitaria en hospitales y clínicas. Estos hallazgos muestran una posible reducción en los informes de trauma y una menor demanda de asistencia durante la pandemia.

Abstract Introduction: Trauma is the second leading cause of mortality and the sixth leading cause of hospitalization in the country, with violence, accidents, and falls being the most prevalent. However, the country is experiencing reflexes of the COVID-19 pandemic, together with a lack of studies on trauma, as well as on clinical care. Objective: To analyze the clinical and epidemiological characteristics of trauma related to violence, accidents, and falls among the years 2019, 2020, and 2021, considered as before and during the COVID-19 pandemic. Material and Methods: Retrospective cohort study, with adults aged 25-55 years, who suffered trauma related to violence, falls, and other accidents, in the period between March and June of 2019, 2020, and 2021, in the city of São Paulo. Data surveys were carried out using the TABNET system, of the Municipal Health Department. Within this system, the search was carried out through the Information System for the Surveillance of Accidents, of the Coordination of Health Surveillance, in which situations of violence were notified and recorded by the National Information System for Notifiable Diseases. Subsequently, the Information System for Surveillance of Violence and Accidents was accessed, focusing on notifications and records of falls and other accidents. Results: Trauma remained more prevalent for males, with complete primary education, and ethnicity predominantly between white or brown. When analyzing the different types of violence: physical, torture, and sexual, there was a prevalence of higher percentages during the year 2019, the pre-pandemic period of COVID-19, except for psychological/moral violence, which was higher in 2021. It should also be noted that the different mechanisms of violence were significantly more prevalent in 2019, as well as the different causes of violence, falls, and car trauma involving pedestrians, occupants, drivers, and passengers. Outpatient care confirmed the higher trend in the pre-pandemic period; however, emergency hospital care showed a greater number of requests in 2020 and 2021. Conclusión: Trauma from violence, accidents, and falls was higher pre-pandemic compared to the period during the COVID-19 pandemic; as well as the search for health care in hospitals and outpatient clinics. These findings show a possible reduction in trauma reports and lower demand for assistance during the pandemic.

12.

Nursing diagnoses of newborns in rooming-in care using ICNP®
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Almeida, Viviane Saraiva de

; Andrade, Marilda

; Querido, Danielle Lemos

; Esteves, Ana Paula Vieira dos Santos

; Nóbrega, Maria Miriam Lima da

; Christoffel, Marialda Moreira

; Leite, Helder Camilo

Revista Brasileira de Enfermagem

Journal Metrics
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2022, Volume 75 N. 4 elocation e20200672

Abstract: Pt En Es | Text: Pt En Es | PDF: Pt | PDF: En | PDF: Es

RESUMO Objetivos: construir enunciados diagnósticos de enfermagem para recém-nascidos internados no alojamento conjunto, utilizando Classificação Internacional para a Prática de Enfermagem (CIPE®). Métodos: estudo metodológico seguindo as etapas de identificação e validação de termos relevantes para o cuidado com a clientela; mapeamento cruzado dos termos identificados com os termos da CIPE® 2019; construção e validação dos enunciados de diagnósticos de enfermagem da CIPE® e subsequente classificação segundo as Necessidades Humanas Básicas descritas por Wanda Horta. Resultados: dos termos extraídos, 168 foram validados com base no consenso (100%) entre especialistas, subsidiando a elaboração de 27 enunciados diagnósticos. Conclusões: os diagnósticos mais frequentes para a clientela estudada foram: “Padrão de Ingestão de Alimentos, Eficaz” “Urina, Normal”, “Ritmo Respiratório, Normal”, “Deglutição, Eficaz, “Acesso Intravenoso Periférico, Eficaz” e “Ligação Afetiva Pais-criança, Eficaz”, confirmando o predomínio do registro das necessidades psicobiológicas pelos enfermeiros, representadas por 23 diagnósticos do estudo.

ABSTRACT Objectives: to create nursing diagnosis definitions for newborns in rooming-in care, using the International Classification for Nursing Practice (ICNP). Methods: methodological study following the steps for the identification and validation of relevant terms to care for clients; cross-mapping of the terms identified with the terms of the ICNP® 2019; elaboration and validation of the nursing diagnostic definitions of ICNP® and later classification according with the Basic Human Needs described by Wanda Horta. Results: from the terms extracted, 168 were validated through specialist consensus, subsidizing the elaboration of 27 diagnosis definitions. Conclusions: the most common diagnoses for the clients studied were: “Effective Feeding Behaviour”, “Effective Urination”, “Normal Respiration Rhythm”, “Effective Swallowing”, “Effective Peripheral Intravenous Access”, and “Effective Parent Child Attachment”. It was confirmed that the records of psychobiological needs are mainly made by nurses, which were responsible for 23 of the diagnoses in this study.

RESUMEN Objetivos: construir enunciados diagnósticos de enfermería para recién nacidos internados en alojamiento conjunto, utilizando Clasificación Internacional para la Práctica de Enfermería (CIPE®). Métodos: estudio metodológico siguiendo las etapas de identificación y validación de términos relevantes para el cuidado con la clientela; mapeo cruzado de los términos identificados con los términos de la CIPE® 2019; construcción y validación de los enunciados de diagnósticos de enfermería de la CIPE® y subsecuente clasificación segundo las Necesidades Humanas Básicas descritas por Wanda Horta. Resultados: de los términos extraídos, 168 fueron validados basados en el consenso (100%) entre especialistas, subsidiando la elaboración de 27 enunciados diagnósticos. Conclusiones: los diagnósticos más frecuentes para la clientela estudiada fueron: “Patrón de Ingestión de Alimentos, Eficaz” “Orina, Normal”, “Ritmo Respiratorio, Normal”, “Deglución, Eficaz, “Acceso Intravenoso Periférico, Eficaz” y “Relación Afectiva Padres-niño, Eficaz”, confirmando el predominio del registro de las necesidades psicobiológicas por enfermeros, representadas por 23 diagnósticos del estudio.

https://doi.org/10.1590/0034-7167-2020-0672

13.

Evaluation of pulse wave velocity and central systolic blood pressure in children and adolescents with chronic kidney disease
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Brecheret, Ana Paula

; Abreu, Ana Lucia Cardoso Santos

; Lopes, Renata

; Fonseca, Francisco Antônio Helfenstein

; Solé, Dirceu

; Andrade, Maria Cristina de

einstein (São Paulo)

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2022, Volume 20 elocation eAO6758

Abstract: En | Text: En | PDF: En

ABSTRACT Objective Investigate pulse wave velocity and central systolic blood pressure among pediatric population with chronic kidney disease. Methods In this cross-sectional study, 57 patients (61.4% male) aged 6.2 to 17.5 years old, 44 with nondialysis chronic kidney disease and 13 on chronic dialysis, were included in the analysis. The pulse wave velocity and the central systolic blood pressure were measured with an oscillometric device with an inbuilt ARC SolverⓇ algorithm and were compared with previously established percentiles. Results The prevalence of elevated pulse wave velocity was 21.1% (95%Cl: 11.4-33.9) and elevated central systolic blood pressure was 28.1% (95%CI: 17.0-41.5). According to the generalized linear model, there was a higher risk of elevated pulse wave velocity in patients undergoing chronic dialysis treatment than nondialysis chronic kidney disease patients (adjPR=4.24, 95%CI: 1.97-9.13, p=<0.001). Hypertensive patients (stage 2) had a higher risk of elevated pulse wave velocity than normotensive ones (adjPR=2.70, 95%CI: 1.05-6.95, p=0.040), as did patients younger than 12 years than the older patients (adjPR=2.95, 95%CI: 1.05-8.40, p=0.041). Hypertensive patients had a higher risk of elevated central systolic blood pressure than normotensives (adjPR=3.29, 95%Cl: 1.36-7.94), as did patients undergoing chronic dialysis treatment when comparing to nondialysis chronic kidney disease patients (adjPR=2.08, 95%Cl: 1.07-4.02). Conclusion Younger age, dialysis, and hypertension in children are independently associated with higher pulse wave velocity. Hypertension and dialysis are independently associated with higher central systolic blood pressure.

https://doi.org/10.31744/einstein_journal/2022ao6758

14.

Support provided to nursing students in the face of patient safety incidents: a qualitative study
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Tavares, Ana Paula Mousinho

; Barlem, Jamila Geri Tomaschewski

; Silveira, Rosemary Silva da

; Dalmolin, Graziele de Lima

; Feijó, Gabrielle dos Santos

; Machado, Isaquiael Andrade

; Paloski, Gabriela do Rosário

; Abreu, Ingrid Moura de

Revista Brasileira de Enfermagem

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2022, Volume 75 N. 2 elocation e20220009

Abstract: Pt En Es | Text: Pt En Es | PDF: Pt | PDF: En | PDF: Es

RESUMO Objetivos: conhecer o suporte ofertado ao estudante de enfermagem após um incidente de segurança do paciente. Métodos: pesquisa qualitativa, desenvolvida com 23 estudantes de um curso de bacharelado de enfermagem do Sul do Brasil. Os dados foram coletados entre setembro e novembro de 2021 e submetidos à análise textual discursiva, com a utilização do software Iramuteq. Resultados: os estudantes relataram que receberam apoio principalmente dos colegas e professores das disciplinas do campo de prática, mas demonstraram desconhecer qualquer tipo de suporte organizacional, protocolo ou apoio quando se encontram na condição de segunda vítima desses incidentes. Considerações Finais: foram identificadas as principais fontes de apoio quando o estudante de enfermagem se envolve em incidentes de segurança do paciente. Destaca-se a incipiência dos recursos de suporte oferecidos a esse estudante, tanto nacional como internacionalmente, sendo prementes mais pesquisas direcionadas a essas potenciais vítimas, bem como recursos de suporte para mitigar esse fenômeno.

ABSTRACT Objectives: to identify the support provided to nursing students after a patient safety incident. Methods: qualitative study developed with 23 students attending an undergraduate nursing program in southern Brazil. Data were collected between September and November 2021 and submitted to textual discursive analysis using the Iramuteq software. Results: the students reported that mainly classmates and professors of the practical courses provided support. The students showed no knowledge of organizational support or protocols available to students who become second victims of such incidents. Final Considerations: the primary support sources available to nursing students involved in patient safety incidents were identified. Note that support provided to nursing students is still incipient both in Brazil and internationally. Hence, further studies are needed to address potential victims and support resources to mitigate this phenomenon.

RESUMEN Objetivos: conocer el soporte ofrecido al estudiante de enfermería después de un incidente de seguridad del paciente. Métodos: investigación cualitativa, desarrollada en el curso de licenciatura de enfermería en el Sur de Brasil, con 23 estudiantes. Los datos fueron recolectados entre septiembre y noviembre de 2021 y sometidos al análisis textual discursivo, con la utilización del software Iramuteq. Resultados: los estudiantes relataron que recibieron apoyo principalmente de los compañeros y profesores de las materias del campo de práctica; también, ellos demostraron no conocer ningún tipo de soporte organizacional, protocolo o apoyo cuando son por segunda vez víctimas de esos incidentes. Consideraciones Finales: se identificaron las principales fuentes de apoyo, cuando el estudiante de enfermería se envuelve en incidentes de seguridad del paciente. Se destaca la insipiencia de los recursos de soporte ofrecidos al estudiante de enfermería, tanto en el ámbito nacional como internacional; así, es necesario realizar más investigaciones dirigidas a esas potenciales víctimas e proporcionar recursos de soporte para mitigar ese fenómeno.

https://doi.org/10.1590/0034-7167-2022-0009

15.

Massas Pericárdicas: Apresentação Rara de Pericardite Tuberculosa, Documentada em Ecocardiografia 3D
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Felix, Alex dos Santos

; Fonseca, Viviane Belidio Pinheiro da

; Segalote, Rodrigo Coelho

; Andrade, Larissa Franco de

; Palmieri, Deborah Louize da Rocha Vianna

; Siciliano, Ana Paula dos Reis Velloso

Arquivos Brasileiros de Cardiologia

Journal Metrics
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feb 2021, Volume 116 N. 2 Pages 12 - 16

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

https://doi.org/10.36660/abc.20190876 514 downloads

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