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Abstract Objective To evaluate clinical characteristics and outcomes of COVID-19 patients infected with HIV, and to compare with a paired sample without HIV infection. Methods This is a substudy of a Brazilian multicentric cohort that comprised two periods (2020 and 2021). Data was obtained through the retrospective review of medical records. Primary outcomes were admission to the intensive care unit, invasive mechanical ventilation, and death. Patients with HIV and controls were matched for age, sex, number of comorbidities, and hospital of origin using the technique of propensity score matching (up to 4:1). They were compared using the Chi-Square or Fisher's Exact tests for categorical variables and the Wilcoxon for numerical variables. Results Throughout the study, 17,101 COVID-19 patients were hospitalized, and 130 (0.76%) of those were infected with HIV. The median age was 54 (IQR: 43.0;64.0) years in 2020 and 53 (IQR: 46.0;63.5) years in 2021, with a predominance of females in both periods. People Living with HIV (PLHIV) and their controls showed similar prevalence for admission to the ICU and invasive mechanical ventilation requirement in the two periods, with no significant differences. In 2020, in-hospital mortality was higher in the PLHIV compared to the controls (27.9% vs. 17.7%; p = 0.049), but there was no difference in mortality between groups in 2021 (25.0% vs. 25.1%; p > 0.999). Conclusions Our results reiterate that PLHIV were at higher risk of COVID-19 mortality in the early stages of the pandemic, however, this finding did not sustain in 2021, when the mortality rate is similar to the control group.

https://doi.org/10.1016/j.clinsp.2023.100223

Body mass index and gestational weight gain: relevance in gestational diabetes and outcomes - A retrospective cohort study
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Rosinha, Patrícia Mendonça Oliveira

; Dantas, Rosa Alexandra Barbosa

; Alves, Márcia Inês Paiva

; Azevedo, Teresa Cristina Maia Ferreira

; Inácio, Isabel Maria Ramos

; Ferreira, Sara Gabriela Esteves

; Pedrosa, Carla Alexandra Vieira

; Ferreira, Marília Sousa

; Sousa, Isabel Maria Albuquerque

; Costa, Joana Guimarães Martins da

Archives of Endocrinology and Metabolism

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apr 2022, Volume 66 N. 2 Pages 261 - 268

Abstract: En | Text: En | PDF: En

ABSTRACT Objective: To evaluate the influence of maternal pre-pregnancy body mass index (BMI) and gestational weight gain (GWG) on blood glucose levels at diagnosis of gestational diabetes mellitus (GDM) and obstetric/neonatal outcomes. Subjects and methods: Retrospective cohort study including 462 women with GDM and singleton pregnancy delivered in our institution between January 2015 and June 2018 and grouped according to BMI/GWG. Results: The diagnosis of GDM was more likely to be established in the 1st trimester (T) in women with obesity than in normal-weight (55.8% vs 53.7%, p = 0.008). BMI positively and significantly correlated with fasting plasma glucose (FPG) levels in the 1stT (rs = 0.213, p = 0.001) and 2ndT (rs = 0.210, p = 0.001). Excessive GWG occurred in 44.9% women with overweight and in 40.2% with obesity (p < 0.001). From women with obesity, 65.1% required pharmacological treatment (p < 0.001). Gestational hypertension (GH) was more frequent in women with obesity (p = 0.016). During follow-up, 132 cesareans were performed, the majority in mothers with obesity (p = 0.008). Of the 17 large-for-gestational-age (LGA) birthweight delivered, respectively 6 and 9 were offsprings of women with overweight and obesity (p = 0.019). Maternal BMI had a predictive value only for macrosomia [aOR 1.177 (1.006-1.376), p = 0.041]. BMI and GWG positively correlated with birthweight (rs = 0.132, p = 0.005; rs = 0.188, p = 0.005). Conclusion: Maternal obesity is related with a major probability of diagnosis of GDM in 1stT, fasting hyperglycemia in 2ndT and a more frequent need for pharmacological therapy. Pre-gestational obesity is associated with GH, cesarean delivery and fetal macrosomia.

https://doi.org/10.20945/2359-3997000000463

Body mass index and gestational weight gain: relevance in gestational diabetes and outcomes - A retrospective cohort study
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Rosinha, Patrícia Mendonça Oliveira

; Dantas, Rosa Alexandra Barbosa

; Alves, Márcia Inês Paiva

; Azevedo, Teresa Cristina Maia Ferreira

; Inácio, Isabel Maria Ramos

; Ferreira, Sara Gabriela Esteves

; Pedrosa, Carla Alexandra Vieira

; Ferreira, Marília Sousa

; Sousa, Isabel Maria Albuquerque

; Costa, Joana Guimarães Martins da

Archives of Endocrinology and Metabolism

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2022, N. ahead

Abstract: En | Text: En | PDF: En

https://doi.org/10.20945/2359-3997000000463

Aspectos fenológicos reprodutivos de Qualea grandiflora Mart. em Cerrado
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Almeida, Sabrina Emanuella da Silva

; Silva, Patricia Oliveira da

; Oliveira, Thaís Cristina Sousa de

; Menino, Gisele Cristina de Oliveira

; Alves, Rauander Douglas Ferreira Barros

Ciência Florestal

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jun 2021, Volume 31 N. 2 Pages 920 - 934

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Qualea grandiflora é uma espécie típica da fisionomia cerradão, de importância ecológica, florística e medicinal. No entanto, são pouco os estudos no que se refere a sua fenologia. Diante do exposto, objetivou-se verificar a sazonalidade e influência das variáveis climáticas nos eventos reprodutivos de Qualea grandiflora em cerradão. Marcaram-se 15 indivíduos que foram visitados mensalmente entre julho de 2016 e junho de 2018 para registrar os eventos: botões florais, antese, frutos imaturos e maduros. A intensidade de Fournier e sincronia foram correlacionadas com a precipitação, temperatura máxima, média e mínima através da correlação de Spearman, e a sazonalidade por meio da estatística circular. A espécie produziu botões e flores durante a estação chuvosa, o que resultou em correlação positiva com a precipitação. A formação de frutos ocorreu tanto na época chuvosa quanto na seca, já a maturação dos frutos ocorreu na estação seca. O evento de frutos imaturos foi o único não sazonal devido a sua duração. Os eventos reprodutivos de Qualea grandiflora se correlacionaram com a temperatura e a precipitação, de modo que a espécie utiliza essa influência para potencializar suas chances de reprodução.

Abstract Qualea grandiflora is a typical species of the ‘Cerradão’ physiognomy, of ecological, floristic and medicinal importance. However, there are few studies regarding to its phenology. In view of the above, the objective was to verify the seasonality and the influence of the climatic variables on the reproductive events of Qualea grandiflora in ‘Cerradão’. Fifteen (15) individuals were visited and visited monthly between July 2016 and June 2018 to record the events: flower buds, anthesis, immature and ripe fruits. Fournier's intensity and synchrony were correlated with precipitation, maximum, average and minimum temperature through the Spearman's correlation, and seasonality using circular statistics. The species itself produced buds and flowers during the rainy season, which resulted in a positive correlation with precipitation. The fruit formation occurred both in the rainy and dry season, whereas the fruit ripening occurred in the dry season. The immature fruit event was the only non-seasonal event due to its duration. The reproductive events of Qualea grandiflora correlated with temperature and precipitation, so the species uses this influence to enhance its chances of reproduction.

https://doi.org/10.5902/1980509839037 4 downloads

Cytogenetic and molecular characteristics of Potamotrygon motoro and Potamotrygon sp. (Chondrichthyes, Myliobatiformes, Potamotrygonidae) from the Amazon basin: Implications for the taxonomy of the genus
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Cruz, Vanessa Paes da

; Nobile, Maria Ligia Oliveira

; Paim, Fabilene Gomes

; Adachi, Aisni Mayumi Correia de Lima

; Ribeiro, Giovana da Silva

; Ferreira, Daniela Cristina

; Pansonato-Alves, José Carlos

; Charvet, Patrícia

; Oliveira, Claudio

; Foresti, Fausto

Genetics and Molecular Biology

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2021, Volume 44 N. 2 elocation e20200083

Abstract: En | Text: En | PDF: En

Abstract The chromosomes of two freshwater stingrays, Potamotrygon motoro and Potamotrygon sp., from the Amazon River basin in Brazil were investigated using integrated molecular (cytochrome c oxidase subunit 1) and cytogenetic analyses. Potamotrygon motoro presented intraspecific variation in the diploid number, with 2n=66 in the females and 2n=65 in the males, while Potamotrygon sp. had a karyotype with 66 chromosomes, in both sexes. The C-banding revealed the presence of heterochromatic blocks accumulated in the centromeric region of all the chromosomes in both species. The FISH assays with 18S DNA probes highlighted the terminal region of three or four chromosome pairs in P. motoro and seven chromosomes in Potamotrygon sp. The rDNA 5S sequences were found in only one chromosomal pair in both species. The interspecific genetic distance based on the COI sequences, between P. motoro and Potamotrygon sp. from Amazon River was 10.8%, while that between the Amazonian P. motoro and Potamotrygon amandae from the Paraná River was 2.2%, and the genetic distance between Potamotrygon sp. and P. amandae was 11.8%. In addition to the new insights on the cytogenetics of the study species, the results of the present study confirmed the existence of heteromorphic sex-linked chromosomes in P. motoro.

https://doi.org/10.1590/1678-4685-gmb-2020-0083 594 downloads

COMVC-19: A Program to protect healthcare workers’ mental health during the COVID-19 Pandemic. What we have learned
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Fukuti, Pedro

; Uchôa, Caroline Louise Mesquita

; Mazzoco, Marina Flaborea

; Cruz, Isabella D'Andrea Garcia da

; Echegaray, Mariana V.F.

; Humes, Eduardo de Castro

; Silveira, Júlia Belizário

; Santi, Talita Di

; Miguel, Euripedes Constantino

; Corchs, Felipe

; Fatori, Daniel

; Campello, Guilherme

; Oliveira, Gabriel M. de

; Argolo, Felipe C.

; Ferreira, Felipe de M.

; Machado, Gustavo

; Argeu, Adriana

; Oliveira, Graça Maria Ramos de

; Serafim, Antônio de Pádua

; Siqueira, Luciana de Lima

; Rossi, Luciane de

; Rios, Izabel Cristina

; Oliveira, Talita Rodrigues de

; Antoniazzi, Leilane C. K.

; Gagliotti, Daniel Augusto Mori

; Abelama Neto, Emílio

; Oliveira Junior, Paulo Novais de

; Correia, Aline Villalobo

; Gonçalves, Luca Schilling

; Tortato, Liana Silva

; Busato, Wagner Machado Moraes

; Guimarães-Fernandes, Flávio

; Alves, Marcos

; Leite Netto, Oswaldo Ferreira

; Schoueri, Patrícia de Campos Lindenberg

; Roque, Márcio de Assis

; Merlin, Silvia Stahl

; Boer, Giovana Cardoso Machado

; Sallet, Paulo Clemente

; Malbergier, André

; Spedo, Mariana Abrahão

; Kamitsuji, Carla Satie

; Faria, Elizabeth de

; Moreira, Moacyr Vergara de Godoy

; Kaufman, Arthur

; Abdo, Carmita

; Scanavino, Marco de Tubino

; Lancman, Selma

; Tavares, Hermano

; Polanczyk, Guilherme

; Brunoni, André R.

; Forlenza, Orestes V.

; Barros-Filho, Tarcísio Eloy Pessoa de

Clinics

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2021, Volume 76 elocation e2631

Abstract: En | Text: En | PDF: En

OBJECTIVE: In 2020, the COVID-19 pandemic brought a work and stress overload to healthcare workers, increasing their vulnerability to mental health impairments. In response, the authors created the COMVC-19 program. The program offered preventive actions and mental health treatment for the 22,000 workers of The Hospital das Clinicas da Faculdade de Medicina da Universidade de São Paulo (HCFMUSP). This paper aims to describe its implementation and share what we have learned from this experience. METHODS: Workers were able to easily access the program through a 24/7 hotline. Additionally, a mobile phone app that screened for signs and symptoms of emotional distress and offered psychoeducation and/or referral to treatment was made available. Data from both these sources as well as any subsequent psychiatric evaluations were collected. RESULTS: The first 20 weeks of our project revealed that most participants were female, and part of the nursing staff working directly with COVID-19 patients. The most frequently reported symptoms were: anxiety, depression and sleep disturbances. The most common diagnoses were Adjustment, Anxiety, and Mood disorders. CONCLUSIONS: Implementing a mental health program in a multimodal intervention was feasible in a major quaternary public hospital. Our data also suggests that preventive actions should primarily be aimed at anxiety and depression symptoms, with a particular focus on the nursing staff.

https://doi.org/10.6061/clinics/2021/e2631

Metodologia e indicadores para monitoramento da NBCAL em estabelecimentos comerciais e serviços de saúde: estudo multicêntrico (Multi-NBCAL)
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Boccolini, Cristiano Siqueira

; Oliveira, Maria Inês Couto de

; Toma, Tereza Setsuko

; Peres, Patricia Lima Pereira

; Santos, Evangelia Kotzias Atherino dos

; Passos, Maria Cristina

; Gubert, Muriel Bauermann

; Sá, Naíza Nayla Bandeira de

; Vianna, Rodrigo Pinheiro de Toledo

; Gomes, Daniela Lopes

; Silva, Talita Maria Alves Lopes da

; Sally, Enilce de Oliveira Fonseca

; Rea, Marina Ferreira

Cadernos de Saúde Pública

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2021, Volume 37 Suppl. 1 elocation e00272920

Abstract: Pt En Es | Text: Pt En Es | PDF: Pt | PDF: En | PDF: Es

A Norma Brasileira de Comercialização de Alimentos para Lactentes e Crianças de Primeira Infância, Bicos, Chupetas e Mamadeiras (NBCAL), vigente no Brasil desde 1988, ainda é sistematicamente infringida, expondo mães e familiares ao marketing ilegal de produtos que competem com o aleitamento materno. O objetivo foi descrever metodologia de estudo multicêntrico e propor indicadores padronizados para monitoramento da NBCAL. Estudo Multicêntrico para Monitoramento da NBCAL (Multi-NBCAL) conduzido em sete cidades brasileiras: Rio de Janeiro; São Paulo; Ouro Preto (Minas Gerais); Florianópolis (Santa Catarina); Brasília (Distrito Federal); João Pessoa (Paraíba) e Belém (Pará). Instrumentos de avaliação foram adaptados do NetCode/WHO e da IBFAN Brasil (Rede Internacional em Defesa do Direito de Amamentar) para condução de dois inquéritos: (1) avaliação do cumprimento da NBCAL em estabelecimentos comerciais e das práticas e conhecimento dos seus gerentes sobre a NBCAL; (2) avaliação em maternidades da interação da indústria de alimentos infantis com profissionais de saúde e mães. Foram elaborados cinco indicadores para avaliação do cumprimento da NBCAL em estabelecimentos comerciais; sete indicadores para avaliar conhecimentos e práticas dos seus responsáveis; cinco indicadores para avaliar a oferta de incentivos a maternidades, profissionais de saúde e mães pelas indústrias e cinco indicadores para avaliar conhecimento e práticas de profissionais de saúde quanto à NBCAL. A metodologia de avaliação da NBCAL, com a proposta de indicadores padronizados, permite a comparabilidade de estudos sobre o tema. A utilização desses indicadores em inquéritos periódicos, nacionais ou regionais, pode contribuir para monitorar o grau de implementação da NBCAL no Brasil.

The Brazilian Code of Marketing of Infant and Toddlers Food, Nipples, Pacifiers and Baby Bottles (NBCAL), in force in Brazil since 1988, is still systematically violated, exposing mothers and family members to illegal marketing of products that compete with breastfeeding. This study aimed to describe a multicenter study methodology and propose standardized indicators for NBCAL monitoring. This is a Multicenter Study for NBCAL Compliance Assessment (Multi-NBCAL) conducted in seven Brazilian cities: Rio de Janeiro, São Paulo, Ouro Preto (Minas Gerais State), Florianópolis (Santa Catarina State), Brasília (Federal District), João Pessoa (Paraíba State), and Belém (Pará State). Assessment tools were adapted from NetCode/WHO and IBFAN Brazil (International Baby Food Action Network) to conduct two evaluations: (1) evaluation of NBCAL compliance in stores, and NBCAL knowledge and practices of store managers; (2) evaluation of the interaction between the baby food industry and health professionals and post-partum mothers in maternity hospitals. Five indicators were developed to assess NBCAL compliance in stores; seven indicators to assess the knowledge and practices of store managers; five indicators to assess the provision of incentives to maternity hospitals, health professionals, and mothers by sectors; and five indicators to assess NBCAL knowledge and practices of health professionals. The NBCAL assessment methodology with the proposal of standardized indicators allows comparability of studies about this theme. Using these indicators in periodic national or regional investigation can help monitor the level of NBCAL implementation in Brazil.

La Norma Brasileña de Comercialización de Alimentos para Lactantes y Niños en la Primera Infancia, Tetillas, Chupetes y Biberones (NBCAL), vigente en Brasil desde 1988, todavía es sistemáticamente infringida, exponiendo a madres y familiares al marketing ilegal de productos que compiten con la lactancia materna. El objetivo fue describir la metodología de estudio multicéntrico y proponer indicadores estandarizados para el monitoreo de la NBCAL. Estudio Multicéntrico para Monitoreo de la NBCAL (Multi-NBCAL) llevado a cabo en siete (7) ciudades brasileñas: Río de Janeiro; São Paulo; Ouro Preto (Minas Gerais); Florianópolis (Santa Catarina); Brasilia (Distrito Federal); João Pessoa (Paraíba) y Belém (Pará). Se adaptaron instrumentos de evaluación del NetCode/OMS y de la IBFAN Brasil (Red Internacional de Acción por la Alimentación Infantil)para la realización de dos encuestas: (1) evaluación del cumplimiento de la NBCAL en establecimientos comerciales y de las prácticas y conocimiento de sus gerentes sobre la NBCAL; (2) evaluación en maternidades de la interacción de la industria de alimentos infantiles con profesionales de salud y madres. Se elaboraron cinco indicadores para la evaluación del cumplimiento de la NBCAL en establecimientos comerciales; siete indicadores para evaluar conocimientos y prácticas de sus responsables; cinco indicadores para evaluar la oferta de incentivos a maternidades, profesionales de salud y madres por las industrias y cinco indicadores para evaluar el conocimiento y prácticas de profesionales de salud, respecto a la NBCAL. La metodología de evaluación de la NBCAL, con la propuesta de indicadores estandarizados, permite la comparabilidad de estudios sobre el tema. La utilización de estos indicadores en encuestas periódicas, nacionales o regionales, puede contribuir a monitorear el grado de implementación de la NBCAL en Brasil.

https://doi.org/10.1590/0102-311x00272920

Metodologia e indicadores para monitoramento da NBCAL em estabelecimentos comerciais e serviços de saúde: estudo multicêntrico (Multi-NBCAL)
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Boccolini, Cristiano Siqueira

; Oliveira, Maria Inês Couto de

; Toma, Tereza Setsuko

; Peres, Patricia Lima Pereira

; Santos, Evangelia Kotzias Atherino dos

; Passos, Maria Cristina

; Gubert, Muriel Bauermann

; Sá, Naíza Nayla Bandeira de

; Vianna, Rodrigo Pinheiro de Toledo

; Gomes, Daniela Lopes

; Silva, Talita Maria Alves Lopes da

; Sally, Enilce de Oliveira Fonseca

; Rea, Marina Ferreira

Cadernos de Saúde Pública

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2021, Volume 37 Suppl. 1 elocation e00272920

Abstract: Pt En Es | Text: Pt En Es | PDF: Pt | PDF: En | PDF: Es

https://doi.org/10.1590/0102-311x00272920

Escore de Cálcio Coronário e Estratificação do Risco de Doença Arterial Coronariana em Pacientes com Acidente Vascular Encefálico Isquêmico Aterosclerótico e não-Aterosclerótico
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Negrão, Edson Marcio

; Freitas, Maria Cristina Del Negro Barroso

; Marinho, Patricia Beatriz Christino

; Hora, Thiago Falcão

; Montanaro, Vinicius Viana Abreu

; Martins, Bernardo Jose Alves Ferreira

; Ramalho, Sergio Henrique Rodolpho

Arquivos Brasileiros de Cardiologia

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dec 2020, Volume 115 N. 6 Pages 1144 - 1151

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Fundamento O acidente vascular encefálico isquêmico (AVEi) e a doença arterial coronariana (DAC) coexistem frequentemente e compartilham fatores de risco para doença aterosclerótica. Segundo a American Heart Association , os subtipos de AVEi podem ser considerados equivalentes de risco para DAC, mas a evidência para o AVEi não-aterosclerótico não está bem definida. Além disso, o escore de cálcio coronário (CAC) é um marcador preciso para estimar o risco de DAC. Entretanto, a distribuição do CAC pelos subtipos de AVEi ainda não foi bem caracterizada. Objetivos Comparar o CAC entre os grupos de AVEi ateroscleróticos e não ateroscleróticos, e determinar quais covariáveis estão associadas a CAC alto no AVEi Métodos Em um estudo transversal, incluímos todos os pacientes com AVEi, com idades entre 45 a 70 anos no momento do acidente vascular, consecutivamente admitidos em um hospital de reabilitação entre agosto de 2014 e dezembro de 2016, sem DAC prevalente. Todos os pacientes passaram por tomografia computadorizada (TC), para medir o CAC. CAC≥100 foi considerado alto risco de DAC. O nível de significância foi p<0,05. Resultados Dos 244 pacientes estudados (média de idade de 58,4±6,8 anos; 49% do sexo feminino), 164 (67%) apresentavam etiologia não-aterosclerótica. As proporções de CAC≥100 foram semelhantes entre os grupos ateroscleróticos e não-ateroscleróticos (33% [n=26] x 29% [n=47]; p= 0,54). Entre todos os pacientes com AVEi, apenas os de idade ≥60 anos foram associados independentemente a CAC≥100 (RC 3,5; 95% IC 1,7-7,1), ajustado para hipertensão, dislipidemia, diabetes, sedentarismo, e histórico familiar de DAC. Conclusão O AVEi aterosclerótico não apresentou risco maior de DAC quando comparado ao AVEi não-aterosclerótico de acordo com o CAC. Apenas a faixa etária ≥60 anos – mas não a etiologia - foi associada independentemente a CAC≥100. (Arq Bras Cardiol. 2020; 115(6):1144-1151)

Abstract Background Ischemic Stroke (IS) and Coronary Artery Disease (CAD) frequently coexist and share atherosclerotic disease risk factors. According to the American Heart Association, IS subtypes may be considered CAD risk equivalents, but the evidence for non-atherosclerotic IS is uncertain. Additionally, the Coronary Calcium Score (CCS) is an accurate marker to address CAD risk; however, CCS distribution between IS subtypes is not well characterized. Objectives To compare the CCS between atherosclerotic and non-atherosclerotic IS groups; and to determine which covariates were associated with high CCS in IS. Methods This cross-sectional design included all patients with IS, 45 to 70 years of age at the time of the stroke, consecutively admitted to a rehabilitation hospital between August 2014 and December 2016, without prevalent CAD. All patients underwent CT scanning for CCS measurement. CCS≥100 was considered a high risk for CAD, with a significance level of p<0.05. Results From the 244 studied patients (mean age 58.4±6.8 years; 49% female), 164 (67%) had non-atherosclerotic etiology. The proportions of CCS≥100 were similar between the atherosclerotic and the non-atherosclerotic groups (33% [n=26] x 29% [n=47]; p= 0.54). Among all IS patients, only age ≥60 years was independently associated with CCS≥100 (OR 3.5; 95%CI 1.7-7.1), accounting for hypertension, dyslipidemia, diabetes, sedentarism, and family history of CAD. Conclusion Atherosclerotic IS did not present a greater risk of CAD when compared to non-atherosclerotic IS according to CCS. Only age ≥60 years, but not etiology, was independently associated with CCS≥100.

https://doi.org/10.36660/abc.20190616 688 downloads

10.

Diretriz Brasileira de Cardio-oncologia – 2020
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Hajjar, Ludhmila Abrahão

; Costa, Isabela Bispo Santos da Silva da

; Lopes, Marcelo Antônio Cartaxo Queiroga

; Hoff, Paulo Marcelo Gehm

; Diz, Maria Del Pilar Estevez

; Fonseca, Silvia Moulin Ribeiro

; Bittar, Cristina Salvadori

; Rehder, Marília Harumi Higuchi dos Santos

; Rizk, Stephanie Itala

; Almeida, Dirceu Rodrigues

; Fernandes, Gustavo dos Santos

; Beck-da-Silva, Luís

; Campos, Carlos Augusto Homem de Magalhães

; Montera, Marcelo Westerlund

; Alves, Sílvia Marinho Martins

; Fukushima, Júlia Tizue

; Santos, Maria Verônica Câmara dos

; Negrão, Carlos Eduardo

; Silva, Thiago Liguori Feliciano da

; Ferreira, Silvia Moreira Ayub

; Malachias, Marcus Vinicius Bolivar

; Moreira, Maria da Consolação Vieira

; Valente Neto, Manuel Maria Ramos

; Fonseca, Veronica Cristina Quiroga

; Soeiro, Maria Carolina Feres de Almeida

; Alves, Juliana Barbosa Sobral

; Silva, Carolina Maria Pinto Domingues Carvalho

; Sbano, João

; Pavanello, Ricardo

; Pinto, Ibraim Masciarelli F.

; Simão, Antônio Felipe

; Dracoulakis, Marianna Deway Andrade

; Hoff, Ana Oliveira

; Assunção, Bruna Morhy Borges Leal

; Novis, Yana

; Testa, Laura

; Alencar Filho, Aristóteles Comte de

; Cruz, Cecília Beatriz Bittencourt Viana

; Pereira, Juliana

; Garcia, Diego Ribeiro

; Nomura, Cesar Higa

; Rochitte, Carlos Eduardo

; Macedo, Ariane Vieira Scarlatelli

; Marcatti, Patricia Tavares Felipe

; Mathias Junior, Wilson

; Wiermann, Evanius Garcia

; Val, Renata do

; Freitas, Helano

; Coutinho, Anelisa

; Mathias, Clarissa Maria de Cerqueira

; Vieira, Fernando Meton de Alencar Camara

; Sasse, André Deeke

; Rocha, Vanderson

; Ramires, José Antônio Franchini

; Kalil Filho, Roberto

Arquivos Brasileiros de Cardiologia

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nov 2020, Volume 115 N. 5 Pages 1006 - 1043

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

https://doi.org/10.36660/abc.20201006 4180 downloads

11.

Aplicações da Psicologia Positiva no Desenvolvimento Infantil: Uma Revisão de Literatura
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Ferreira, Patricia Cristina

; Lamas, Karen Cristina Alves

Psico-USF

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sep 2020, Volume 25 N. 3 Pages 493 - 505

Abstract: Pt En Es | Text: Pt En Es | PDF: Pt | PDF: En | PDF: Es

Resumo O objetivo deste estudo foi realizar uma revisão integrativa da literatura brasileira sobre as aplicações da Psicologia Positiva no desenvolvimento infantil. Efetuou-se uma busca por artigos científicos nas bases de dados SciELO e PePSIC, com os termos psicologia positiva, resiliência, otimismo, habilidades sociais, bem-estar e felicidade articulados aos termos desenvolvimento infantil, crianças e infância. Foram recuperadas 202 publicações entre os anos 2000 e 2019, entre estas 72 foram analisadas. Observou-se o aumento da produção científica, com destaque para o construto habilidades sociais. Houve predomínio de pesquisas empíricas e análises quantitativas. Contudo, verificou-se poucos estudos sobre a eficácia de intervenções. Conclui-se que é importante diversificar os construtos investigados e investir em desenvolvimento e validação de instrumentos de avaliação e intervenções em diferentes contextos, que proporcionem a potencialização das qualidades humanas na infância em caráter de prevenção e promoção de saúde mental ao longo da vida.

Abstract This study aimed to perform an integrative review of the Brazilian literature on the applications of Positive Psychology in child development. We searched for scientific articles using the SciELO and PePSIC electronic databases, with the terms Positive Psychology, resilience, optimism, social skills, well-being, and happiness articulated to the terms child development, children, and childhood. A total of 202 publications were retrieved between 2000 and 2019, among which 72 were analyzed. We observed an increase in the scientific production on the field, especially about the social skills construct. There was a predominance of empirical research and quantitative analyses. However, there were few studies on the effectiveness of interventions. It was concluded that it is important to diversify the investigated constructs and to invest in the development and validation of evaluation instruments and interventions in different contexts that provide the enhancement of human qualities in childhood for the prevention and promotion of mental health throughout life.

Resumen El objetivo de este estudio fue realizar una revisión integradora de la literatura brasileña sobre las aplicaciones de la Psicología Positiva en el desarrollo infantil. Se realizó una búsqueda de artículos científicos en las bases de datos SciELO y PePSIC, con los términos Psicología Positiva, resiliencia, optimismo, habilidades sociales, bienestar y felicidad, articulados con los términos desarrollo infantil, niños e infancia. Se recuperaron 202 publicaciones entre los años 2000 y 2019, entre esas 72 fueron analizadas. Se observó aumento en la producción científica, con destaque para el constructo habilidades sociales. Predominó la investigación empírica y análisis cuantitativo. Sin embargo, ha habido pocos estudios sobre eficacia de las intervenciones. Se concluye que es importante diversificar los constructos investigados e investir en desarrollo y validación de instrumentos de evaluación e intervenciones en diferentes contextos, que proporcionen mejora en las cualidades humanas en la infancia, en el campo de la prevención y promoción de salud mental a lo largo de la vida.

https://doi.org/10.1590/1413-82712020250308 2484 downloads

12.

The role of kinship in knowledge about medicinal plants: evidence for context-dependent model-based biases in cultural transmission?
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Brito, Camilla de Carvalho de

; Ferreira-Júnior, Washington Soares

; Albuquerque, Ulysses Paulino

; Ramos, Marcelo Alves

; Silva, Taline Cristina da

; Costa-Neto, Eraldo Medeiros

; Medeiros, Patrícia Muniz de

Acta Botanica Brasilica

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jun 2019, Volume 33 N. 2 Pages 370 - 375

Abstract: En | Text: En | PDF: En

ABSTRACT The similarity in traditional knowledge of medicinal plants was evaluated to draw inferences about the most important models for local knowledge transmission. The following questions were addressed: (1) Do related individuals possess greater similarity in knowledge of medicinal plants than unrelated individuals? (2) Do related individuals of the same generation possess greater similarity in knowledge than do related individuals of different generations? Semi-structured interviews were conducted on the medicinal plants known by the residents of a rural community in western Bahia. Mann-Whitney tests were used to compare Jaccard similarity values between related and unrelated individuals and between relatives of the same generation and relatives of different generations. Related individuals were found to have more similar knowledge than unrelated individuals, and relatives of the same generation were found to have more similar knowledge than relatives of different generations. These findings suggest that there are factors that favor cultural transmission between relatives of the same generation other than just vertical transmission.

https://doi.org/10.1590/0102-33062018abb0340 781 downloads

13.

Mycological Diversity Description II
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Silva, Rejane Maria Ferreira da

; Soares, Adriene Mayra

; Pádua, Ana Patrícia Sousa Lopes de

; Firmino, André Luiz

; Souza-Motta, Cristina Maria de

; Silva, Gladstone Alves da

; Plautz Jr, Helio Longoni

; Bezerra, Jadson Diogo Pereira

; Paiva, Laura Mesquita

; Ryvarden, Leif

; Oliani, Luisa Cunha

; Mélo, Mayara Alice Correia de

; Magalhães, Oliane Maria Correia

; Pereira, Olinto L.

; Oliveira, Rafael José Vilela de

; Gibertoni, Tatiana Baptista

; Oliveira, Thays Gabrielle Lins de

; Svedese, Virginia Michelle

; Fan, Xinlei

Acta Botanica Brasilica

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mar 2019, Volume 33 N. 1 Pages 163 - 173

Abstract: En | Text: En | PDF: En

ABSTRACT Here, Diaporthe myracrodruonis is introduced as new species from Brazil, isolated as endophyte from Myracrodruon urundeuva. Asterina mandaquiensis is epitypified and ilustrated for the first time. Serpula similis is reported as new to the Neotropics, while Perenniporia centrali-africana is reported for the first time as endophyte and Preussia africana as endophyte from Spondias tuberosa in Caatinga in Brazil.

https://doi.org/10.1590/0102-33062018abb0411 1255 downloads

14.

BthTX-I from Bothrops jararacussu induces apoptosis in human breast cancer cell lines and decreases cancer stem cell subpopulation
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Bezerra, Patrícia Heloise Alves

; Ferreira, Isadora Marques

; Franceschi, Beatriz Tinoco

; Bianchini, Francine

; Ambrósio, Luciana

; Cintra, Adélia Cristina O.

; Sampaio, Suely Vilela

; Castro, Fabíola Attié de

; Torqueti, Maria Regina

Journal of Venomous Animals and Toxins including Tropical Diseases

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2019, Volume 25 elocation e20190010

Abstract: En | Text: En | PDF: En

ABSTRACT Background: Breast cancer is the neoplasm with both the highest incidence and mortality rate among women worldwide. Given the known snake venom cytotoxicity towards several tumor types, we evaluated the effects of BthTX-I from Bothrops jararacussu on MCF7, SKBR3, and MDAMB231 breast cancer cell lines. Methods: BthTX-I cytotoxicity was determined via MTT 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-tetrazoliumbromide assay. Cell death was measured by a hypotonic fluorescent solution method, annexin-V-FITC/propidium iodide staining and by apoptotic/autophagic protein expression. Cancer stem cells (CSCs) were quantified by flow cytometry using anti-CD24-FITC and anti-CD44-APC antibodies and propidium iodide. Results: BthTX-I at 102 µg/mL induced cell death in all cell lines. The toxin induced apoptosis in MCF7, SKBR3, and MDAMB231 in a dose-dependent manner, as confirmed by the increasing number of hypodiploid nuclei. Expression of pro-caspase 3, pro-caspase 8 and Beclin-1 proteins were increased, while the level of the antiapoptotic protein Bcl-2 was diminished in MCF7 cells. BthTX-I changed the staining pattern of CSCs in MDAMB231 cells by increasing expression of CD24 receptors, which mediated cell death. Conclusions: BthTX-I induces apoptosis and autophagy in all breast cancer cell lines tested and also reduces CSCs subpopulation, which makes it a promising therapeutic alternative for breast cancer.

https://doi.org/10.1590/1678-9199-jvatitd-2019-0010 1729 downloads

15.

Fatores associados à cobertura do Sisvan Web para crianças menores de 5 anos, nos municípios da Superintendência Regional de Saúde de Belo Horizonte, Brasil
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Ferreira, Carolina Souza

; Rodrigues, Letícia Alves

; Bento, Isabel Cristina

; Villela, Maria Patrícia Costa

; Cherchiglia, Mariangela Leal

; César, Cibele Comini

Ciência & Saúde Coletiva

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sep 2018, Volume 23 N. 9 Pages 3031 - 3040

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo O presente trabalho teve como objetivo analisar fatores associados à cobertura do Sistema de Vigilância Alimentar e Nutricional (Sisvan Web) para crianças menores de cinco anos, nos municípios da Superintendência Regional de Saúde de Belo Horizonte (SRS-BH). Foram coletados dados da cobertura do Sisvan Web nos meses de setembro e outubro de 2012, período em que foi enviado um “Questionário semiestruturado sobre o funcionamento do Sisvan” às referências técnicas dos municípios avaliados. A cobertura foi calculada dividindo-se o número de crianças menores de 5 anos acompanhadas no Sisvan, pelo número total de crianças também menores de 5 anos obtido do Censo IBGE 2010. A mediana da cobertura do Sisvan Web para crianças nos municípios da SRS-BH foi de 5,59%, sendo que as coberturas variaram entre 0,55% e 35,8%. De todas as variáveis estudadas, a única que apresentou associação estatisticamente significativa (p < 0,05) com a cobertura do Sisvan Web foi a falta de profissional para coleta de dados. Os resultados encontrados sugerem a necessidade de uma maior sensibilização dos gestores da saúde e dos profissionais de saúde do SUS sobre a importância do diagnóstico da situação alimentar e nutricional da população por meio do Sisvan Web.

Abstract The objective of this research was to analyze the factors associated with the Food and Nutrition Surveillance System (Sisvan Web) coverage for children under five years of age in the municipalities of the Regional Health Inspectorate of Belo Horizonte (HRS-BH). Sisvan Web coverage data were collected from September to October 2012. Simultaneously, a “semi-structured questionnaire about the Sisvan operation” was sent to identify the technical references of municipalities studied. The coverage was calculated by dividing the number of under five-year-old children covered by Sisvan by the total number of similarly under five-year-old children obtained from the 2010 IBGE census. The Median Sisvan Web coverage of children in the HRS-BH municipalities was 5.59%, with coverage values ranging from 0.55% to 35.8%. Among the variables studied, the only one that revealed significant statistical association (p < 0.05) with Sisvan Web coverage was the lack of professionals to collect data. The results revealed the need for greater awareness of health managers and public health professionals about the importance of the nutritional diagnosis situation of the population through Sisvan Web.

https://doi.org/10.1590/1413-81232018239.15922016 1759 downloads

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