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1.
The Influence of the Acyl Side Chain on Pyrene Excimer Formation as a Model for Asphaltene Aggregation
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Alvarenga, Suyane D. S. de
; Garden, Simon J.
; Forero, Josué S. B.
Teixeira, Raquel S. P.
Souza, Rodrigo S.
Gonçalves, Yan M. H.
Horta, Bruno A. C.
Gomez, Javier A. G.
Santos, Luiz H. C. dos
Ribeiro, Emerson S.
Corrêa, Rodrigo J.


Asphaltene aggregation mechanism is still a nebulous and controversial issue. Many authors argue that the aggregation of its components is due to π-stacking interactions, nonetheless, alkyl chains, heteroatoms, and even acidic groups are also constituents of asphaltenes and can play an important role in the chemistry of asphaltene. Excimers from pyrene are easily detected by fluorescence and were used in the current study to probe the effect of the side chain on the π-stacking capacity of pyrene. Pyrene was acylated with acyl chains varying from two to twelve carbon atoms, and the effect of the variation of the acyl chain length on excimer formation was followed by fluorescence emission spectroscopy. The results revealed that as the side chain grows from two to twelve carbon atoms the excimer/monomer ratio decreases and the excimer heat of formation drops from ΔH = -6.00 to -1.29 kcal mol-1. Further, the crystal structure of octanoyl pyrene (PC8) indicates that in the crystal structure, the aromatic moiety faces the acyl chain. This result was corroborated by density functional theory (DFT) calculations. Finally, the results were compared with two different asphaltenes and indicate that π-stacking cannot be assumed as the main driving force for asphaltene aggregation.
2.
Diretriz Brasileira de Ergometria em Crianças e Adolescentes – 2024
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Carvalho, Tales de
; Freitas, Odilon Gariglio Alvarenga de
; Chalela, William Azem
; Hossri, Carlos Alberto Cordeiro
; Milani, Mauricio
; Buglia, Susimeire
; Falcão, Andréa Maria Gomes Marinho
; Costa, Ricardo Vivacqua Cardoso
; Ritt, Luiz Eduardo Fonteles
; Pfeiffer, Maria Eulália Thebit
; Silva, Odwaldo Barbosa e
; Imada, Rodrigo
; Pena, José Luiz Barros
; Avanza Júnior, Antônio Carlos
; Sellera, Carlos Alberto Cyrillo
; Ferreira, Ana Luíza Guimarães
.
















Classes of Recommendation Class I: Conditions for which there is conclusive evidence and, failing that, general agreement that a given procedure is safe and useful/effective. Class II: Conditions for which there is conflicting evidence and/or a divergence of opinion about the safety and usefulness/efficacy of a procedure. Class IIa: Weight or evidence/opinion in favor of the procedure. Most approve. Class IIb: Safety and usefulness/efficacy less well established, with divergence of opinions. Class III: Conditions for which there is evidence and/or general agreement that a procedure is not useful/effective and, in some cases, may be harmful. Levels of Evidence Level A: Data derived from multiple large, concordant randomized trials and/or robust meta-analyses of randomized trials. Level B: Data derived from less robust meta-analyses, from a single randomized trial and/or from observational studies. Level C: Data derived from consensus opinion of experts.
Classes de Recomendação Classe I: Condições para as quais há evidências conclusivas e, na sua falta, consenso geral de que o procedimento é seguro e útil/eficaz. Classe II: Condições para as quais há evidências conflitantes e/ou divergência de opinião sobre a segurança e utilidade/eficácia do procedimento. Classe IIa: Peso ou evidência/opinião a favor do procedimento. A maioria aprova. Classe IIb: Segurança e utilidade/eficácia menos estabelecidas, havendo opiniões divergentes. Classe III: Condições para as quais há evidências e/ou consenso de que o procedimento não é útil/eficaz e, em alguns casos, pode ser prejudicial. Níveis de Evidência Nível A: Dados obtidos a partir de múltiplos estudos randomizados de bom porte, concordantes e/ou de metanálise robusta de estudos randomizados. Nível B: Dados obtidos a partir de metanálise menos robusta, a partir de um único estudo randomizado e/ou de estudos observacionais. Nível C: Dados obtidos de opiniões consensuais de especialistas.
3.
A infância e a adolescência na política de saúde mental: uma análise por meio dos conselheiros e conferências de saúde
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Resumo O objetivo do trabalho foi analisar como crianças e adolescentes são contemplados nos processos de participação para a formulação das políticas públicas de saúde mental. Pesquisa qualitativa, descritiva e exploratória de caráter documental e de campo. A base de dados da análise documental consistiu em: relatórios das Conferências de Saúde (nacional, estadual e municipal), atas de reuniões do Conselho de Saúde (nacional, estadual e municipal) e memórias da Comissão Temática de Saúde Mental (estadual e municipal). Participaram deste estudo nove conselheiros ou ex-conselheiros de saúde, por meio de uma entrevista individual com roteiro semiestruturado. Como marco teórico de análise desta pesquisa, foi proposto o agir comunicativo de Jürgen Habermas. Dentre os temas que emergiram da pesquisa documental, encontram-se as diretrizes de processos intersetoriais, bem como a ampliação de leitos para crianças e adolescentes. As entrevistas apontaram a falta de discussão da temática, predomínio da perspectiva punitivista e para a necessidade de um debate mais amplo. A falta de espaços intersubjetivos de escuta democrática compromete o agir comunicativo, ocasionando a invisibilização da criança e do adolescente no processo de formulação da política e enfraquecendo os espaços de participação e controle social.
Abstract This qualitative, descriptive, and exploratory documentary and field research aimed to analyze how children and adolescents are included in the formulation of public mental health policies. The document analysis database consisted of reports from Health Conferences (national, state, and municipal), minutes of meetings of the Health Council (national, state, and municipal), and memories of the Thematic Commission on Mental Health (state and municipal). Nine counselors or former health counselors participated in this study through an individual interview with a semi-structured script. Furthermore, the theoretical framework for the analysis of this research was based on the communicative action of Jürgen Habermas. The themes that emerged from the documentary research included the guidelines for intersectoral processes, as well as the expansion of beds for children and adolescents. In addition, the interviews indicated the lack of discussion on the subject, predominance of the punitive perspective, and need for a broader debate. The lack of intersubjective spaces for democratic listening compromises communicative action, resulting in the invisibility of children and adolescents in the policy formulation process and reduced opportunities for participation and social control.
4.
Catálogo Taxonômico da Fauna do Brasil: Setting the baseline knowledge on the animal diversity in Brazil
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Boeger, Walter A.
; Valim, Michel P.
; Zaher, Hussam
; Rafael, José A.
; Forzza, Rafaela C.
; Percequillo, Alexandre R.
; Serejo, Cristiana S.
; Garraffoni, André R.S.
; Santos, Adalberto J.
Slipinski, Adam
Linzmeier, Adelita M.
Calor, Adolfo R.
Garda, Adrian A.
Kury, Adriano B.
Fernandes, Agatha C.S.
Agudo-Padrón, Aisur I.
Akama, Alberto
Silva Neto, Alberto M. da
Burbano, Alejandro L.
Menezes, Aleksandra
Pereira-Colavite, Alessandre
Anichtchenko, Alexander
Lees, Alexander C.
Bezerra, Alexandra M.R.
Domahovski, Alexandre C.
Pimenta, Alexandre D.
Aleixo, Alexandre L.P.
Marceniuk, Alexandre P.
Paula, Alexandre S. de
Somavilla, Alexandre
Specht, Alexandre
Camargo, Alexssandro
Newton, Alfred F.
Silva, Aline A.S. da
Santos, Aline B. dos
Tassi, Aline D.
Aragão, Allan C.
Santos, Allan P.M.
Migotto, Alvaro E.
Mendes, Amanda C.
Cunha, Amanda
Chagas Júnior, Amazonas
Sousa, Ana A.T. de
Pavan, Ana C.
Almeida, Ana C.S.
Peronti, Ana L.B.G.
Henriques-Oliveira, Ana L.
Prudente, Ana L.
Tourinho, Ana L.
Pes, Ana M.O.
Carmignotto, Ana P.
Wengrat, Ana P.G. da Silva
Dornellas, Ana P.S.
Molin, Anamaria Dal
Puker, Anderson
Morandini, André C.
Ferreira, André da S.
Martins, André L.
Esteves, André M.
Fernandes, André S.
Roza, André S.
Köhler, Andreas
Paladini, Andressa
Andrade, Andrey J. de
Pinto, Ângelo P.
Salles, Anna C. de A.
Gondim, Anne I.
Amaral, Antonia C.Z.
Rondón, Antonio A.A.
Brescovit, Antonio
Lofego, Antônio C.
Marques, Antonio C.
Macedo, Antonio
Andriolo, Artur
Henriques, Augusto L.
Ferreira Júnior, Augusto L.
Lima, Aurino F. de
Barros, Ávyla R. de A.
Brito, Ayrton do R.
Romera, Bárbara L.V.
Vasconcelos, Beatriz M.C. de
Frable, Benjamin W.
Santos, Bernardo F.
Ferraz, Bernardo R.
Rosa, Brunno B.
Sampaio, Brunno H.L.
Bellini, Bruno C.
Clarkson, Bruno
Oliveira, Bruno G. de
Corrêa, Caio C.D.
Martins, Caleb C.
Castro-Guedes, Camila F. de
Souto, Camilla
Bicho, Carla de L.
Cunha, Carlo M.
Barboza, Carlos A. de M.
Lucena, Carlos A.S. de
Barreto, Carlos
Santana, Carlos D.C.M. de
Agne, Carlos E.Q.
Mielke, Carlos G.C.
Caetano, Carlos H.S.
Flechtmann, Carlos H.W.
Lamas, Carlos J.E.
Rocha, Carlos
Mascarenhas, Carolina S.
Margaría, Cecilia B.
Waichert, Cecilia
Digiani, Celina
Haddad, Célio F.B.
Azevedo, Celso O.
Benetti, Cesar J.
Santos, Charles M.D. dos
Bartlett, Charles R.
Bonvicino, Cibele
Ribeiro-Costa, Cibele S.
Santos, Cinthya S.G.
Justino, Cíntia E.L.
Canedo, Clarissa
Bonecker, Claudia C.
Santos, Cláudia P.
Carvalho, Claudio J.B. de
Gonçalves, Clayton C.
Galvão, Cleber
Costa, Cleide
Oliveira, Cléo D.C. de
Schwertner, Cristiano F.
Andrade, Cristiano L.
Pereira, Cristiano M.
Sampaio, Cristiano
Dias, Cristina de O.
Lucena, Daercio A. de A.
Manfio, Daiara
Amorim, Dalton de S.
Queiroz, Dalva L. de
Queiroz, Dalva L. de
Colpani, Daniara
Abbate, Daniel
Aquino, Daniel A.
Burckhardt, Daniel
Cavallari, Daniel C.
Prado, Daniel de C. Schelesky
Praciano, Daniel L.
Basílio, Daniel S.
Bená, Daniela de C.
Toledo, Daniela G.P. de
Takiya, Daniela M.
Fernandes, Daniell R.R.
Ament, Danilo C.
Cordeiro, Danilo P.
Silva, Darliane E.
Pollock, Darren A.
Muniz, David B.
Gibson, David I.
Nogueira, David S.
Marques, Dayse W.A.
Lucatelli, Débora
Garcia, Deivys M.A.
Baêta, Délio
Ferreira, Denise N.M.
Rueda-Ramírez, Diana
Fachin, Diego A.
Souza, Diego de S.
Rodrigues, Diego F.
Pádua, Diego G. de
Barbosa, Diego N.
Dolibaina, Diego R.
Amaral, Diogo C.
Chandler, Donald S.
Maccagnan, Douglas H.B.
Caron, Edilson
Carvalho, Edrielly
Adriano, Edson A.
Abreu Júnior, Edson F. de
Pereira, Edson H.L.
Viegas, Eduarda F.G.
Carneiro, Eduardo
Colley, Eduardo
Eizirik, Eduardo
Santos, Eduardo F. dos
Shimbori, Eduardo M.
Suárez-Morales, Eduardo
Arruda, Eliane P. de
Chiquito, Elisandra A.
Lima, Élison F.B.
Castro, Elizeu B. de
Orlandin, Elton
Nascimento, Elynton A. do
Razzolini, Emanuel
Gama, Emanuel R.R.
Araujo, Enilma M. de
Nishiyama, Eric Y.
Spiessberger, Erich L.
Santos, Érika C.L. dos
Contreras, Eugenia F.
Galati, Eunice A.B.
Oliveira Junior, Evaldo C. de
Gallardo, Fabiana
Hernandes, Fabio A.
Lansac-Tôha, Fábio A.
Pitombo, Fabio B.
Dario, Fabio Di
Santos, Fábio L. dos
Mauro, Fabio
Nascimento, Fabio O. do
Olmos, Fabio
Amaral, Fabio R.
Schunck, Fabio
Godoi, Fábio S. P. de
Machado, Fabrizio M.
Barbo, Fausto E.
Agrain, Federico A.
Ribeiro, Felipe B.
Moreira, Felipe F.F.
Barbosa, Felipe F.
Silva, Fenanda S.
Cavalcanti, Fernanda F.
Straube, Fernando C.
Carbayo, Fernando
Carvalho Filho, Fernando
Zanella, Fernando C.V.
Jacinavicius, Fernando de C.
Farache, Fernando H.A.
Leivas, Fernando
Dias, Fernando M.S.
Mantellato, Fernando
Vaz-de-Mello, Fernando Z.
Gudin, Filipe M.
Albuquerque, Flávio
Molina, Flavio B.
Passos, Flávio D.
Shockley, Floyd W.
Pinheiro, Francielly F.
Mello, Francisco de A.G. de
Nascimento, Francisco E. de L.
Franco, Francisco L.
Oliveira, Francisco L. de
Melo, Francisco T. de V.
Quijano, Freddy R.B.
Salles, Frederico F.
Biffi, Gabriel
Queiroz, Gabriel C.
Bizarro, Gabriel L.
Hrycyna, Gabriela
Leviski, Gabriela
Powell, Gareth S.
Santos, Geane B. dos
Morse, Geoffrey E.
Brown, George
Mattox, George M.T.
Zimbrão, Geraldo
Carvalho, Gervásio S.
Miranda, Gil F.G.
Moraes, Gilberto J. de
Lourido, Gilcélia M.
Neves, Gilmar P.
Moreira, Gilson R.P.
Montingelli, Giovanna G.
Maurício, Giovanni N.
Marconato, Gláucia
Lopez, Guilherme E.L.
Silva, Guilherme L. da
Muricy, Guilherme
Brito, Guilherme R.R.
Garbino, Guilherme S.T.
Flores, Gustavo E.
Graciolli, Gustavo
Libardi, Gustavo S.
Proctor, Heather C.
Gil-Santana, Helcio R.
Varella, Henrique R.
Escalona, Hermes E.
Schmitz, Hermes J.
Rodrigues, Higor D.D.
Galvão Filho, Hilton de C.
Quintino, Hingrid Y.S.
Pinto, Hudson A.
Rainho, Hugo L.
Miyahira, Igor C.
Gonçalves, Igor de S.
Martins, Inês X.
Cardoso, Irene A.
Oliveira, Ismael B. de
Franz, Ismael
Fernandes, Itanna O.
Golfetti, Ivan F.
S. Campos-Filho, Ivanklin
Oliveira, Ivo de S.
Delabie, Jacques H.C.
Oliveira, Jader de
Prando, Jadila S.
Patton, James L.
Bitencourt, Jamille de A.
Silva, Janaina M.
Santos, Jandir C.
Arruda, Janine O.
Valderrama, Jefferson S.
Dalapicolla, Jeronymo
Oliveira, Jéssica P.
Hájek, Jiri
Morselli, João P.
Narita, João P.
Martin, João P.I.
Grazia, Jocélia
McHugh, Joe
Cherem, Jorge J.
Farias Júnior, José A.S.
Fernandes, Jose A.M.
Pacheco, José F.
Birindelli, José L.O.
Rezende, José M.
Avendaño, Jose M.
Duarte, José M. Barbanti
Ribeiro, José R. Inácio
Mermudes, José R.M.
Pujol-Luz, José R.
Santos, Josenilson R. dos
Câmara, Josenir T.
Teixeira, Joyce A.
Prado, Joyce R. do
Botero, Juan P.
Almeida, Julia C.
Kohler, Julia
Gonçalves, Julia P.
Beneti, Julia S.
Donahue, Julian P.
Alvim, Juliana
Almeida, Juliana C.
Segadilha, Juliana L.
Wingert, Juliana M.
Barbosa, Julianna F.
Ferrer, Juliano
Santos, Juliano F. dos
Kuabara, Kamila M.D.
Nascimento, Karine B.
Schoeninger, Karine
Campião, Karla M.
Soares, Karla
Zilch, Kássia
Barão, Kim R.
Teixeira, Larissa
Sousa, Laura D. do N.M. de
Dumas, Leandro L.
Vieira, Leandro M.
Azevedo, Leonardo H.G.
Carvalho, Leonardo S.
Souza, Leonardo S. de
Rocha, Leonardo S.G.
Bernardi, Leopoldo F.O.
Vieira, Letícia M.
Johann, Liana
Salvatierra, Lidianne
Oliveira, Livia de M.
Loureiro, Lourdes M.A. El-moor
Barreto, Luana B.
Barros, Luana M.
Lecci, Lucas
Camargos, Lucas M. de
Lima, Lucas R.C.
Almeida, Lucia M.
Martins, Luciana R.
Marinoni, Luciane
Moura, Luciano de A.
Lima, Luciano
Naka, Luciano N.
Miranda, Lucília S.
Salik, Lucy M.
Bezerra, Luis E.A.
Silveira, Luis F.
Campos, Luiz A.
Castro, Luiz A.S. de
Pinho, Luiz C.
Silveira, Luiz F.L.
Iniesta, Luiz F.M.
Tencatt, Luiz F.C.
Simone, Luiz R.L.
Malabarba, Luiz R.
Cruz, Luiza S. da
Sekerka, Lukas
Barros, Lurdiana D.
Santos, Luziany Q.
Skoracki, Maciej
Correia, Maira A.
Uchoa, Manoel A.
Andrade, Manuella F.G.
Hermes, Marcel G.
Miranda, Marcel S.
Araújo, Marcel S. de
Monné, Marcela L.
Labruna, Marcelo B.
Santis, Marcelo D. de
Duarte, Marcelo
Knoff, Marcelo
Nogueira, Marcelo
Britto, Marcelo R. de
Melo, Marcelo R.S. de
Carvalho, Marcelo R. de
Tavares, Marcelo T.
Kitahara, Marcelo V.
Justo, Marcia C.N.
Botelho, Marcia J.C.
Couri, Márcia S.
Borges-Martins, Márcio
Felix, Márcio
Oliveira, Marcio L. de
Bologna, Marco A.
Gottschalk, Marco S.
Tavares, Marcos D.S.
Lhano, Marcos G.
Bevilaqua, Marcus
Santos, Marcus T.T.
Domingues, Marcus V.
Sallum, Maria A.M.
Digiani, María C.
Santarém, Maria C.A.
Nascimento, Maria C. do
Becerril, María de los A.M.
Santos, Maria E.A. dos
Passos, Maria I. da S. dos
Felippe-Bauer, Maria L.
Cherman, Mariana A.
Terossi, Mariana
Bartz, Marie L.C.
Barbosa, Marina F. de C.
Loeb, Marina V.
Cohn-Haft, Mario
Cupello, Mario
Martins, Marlúcia B.
Christofersen, Martin L.
Bento, Matheus
Rocha, Matheus dos S.
Martins, Maurício L.
Segura, Melissa O.
Cardenas, Melissa Q.
Duarte, Mércia E.
Ivie, Michael A.
Mincarone, Michael M.
Borges, Michela
Monné, Miguel A.
Casagrande, Mirna M.
Fernandez, Monica A.
Piovesan, Mônica
Menezes, Naércio A.
Benaim, Natalia P.
Reategui, Natália S.
Pedro, Natan C.
Pecly, Nathalia H.
Ferreira Júnior, Nelson
Silva Júnior, Nelson J. da
Perioto, Nelson W.
Hamada, Neusa
Degallier, Nicolas
Chao, Ning L.
Ferla, Noeli J.
Mielke, Olaf H.H.
Evangelista, Olivia
Shibatta, Oscar A.
Oliveira, Otto M.P.
Albornoz, Pablo C.L.
Dellapé, Pablo M.
Gonçalves, Pablo R.
Shimabukuro, Paloma H.F.
Grossi, Paschoal
Rodrigues, Patrícia E. da S.
Lima, Patricia O.V.
Velazco, Paul
Santos, Paula B. dos
Araújo, Paula B.
Silva, Paula K.R.
Riccardi, Paula R.
Garcia, Paulo C. de A.
Passos, Paulo G.H.
Corgosinho, Paulo H.C.
Lucinda, Paulo
Costa, Paulo M.S.
Alves, Paulo P.
Roth, Paulo R. de O.
Coelho, Paulo R.S.
Duarte, Paulo R.M.
Carvalho, Pedro F. de
Gnaspini, Pedro
Souza-Dias, Pedro G.B.
Linardi, Pedro M.
Bartholomay, Pedro R.
Demite, Peterson R.
Bulirsch, Petr
Boll, Piter K.
Pereira, Rachel M.M.
Silva, Rafael A.P.F.
Moura, Rafael B. de
Boldrini, Rafael
Silva, Rafaela A. da
Falaschi, Rafaela L.
Cordeiro, Ralf T.S.
Mello, Ramon J.C.L.
Singer, Randal A.
Querino, Ranyse B.
Heleodoro, Raphael A.
Castilho, Raphael de C.
Constantino, Reginaldo
Guedes, Reinaldo C.
Carrenho, Renan
Gomes, Renata S.
Gregorin, Renato
Machado, Renato J.P.
Bérnils, Renato S.
Capellari, Renato S.
Silva, Ricardo B.
Kawada, Ricardo
Dias, Ricardo M.
Siewert, Ricardo
Brugnera, Ricaro
Leschen, Richard A.B.
Constantin, Robert
Robbins, Robert
Pinto, Roberta R.
Reis, Roberto E. dos
Ramos, Robson T. da C.
Cavichioli, Rodney R.
Barros, Rodolfo C. de
Caires, Rodrigo A.
Salvador, Rodrigo B.
Marques, Rodrigo C.
Araújo, Rodrigo C.
Araujo, Rodrigo de O.
Dios, Rodrigo de V.P.
Johnsson, Rodrigo
Feitosa, Rodrigo M.
Hutchings, Roger W.
Lara, Rogéria I.R.
Rossi, Rogério V.
Gerstmeier, Roland
Ochoa, Ronald
Hutchings, Rosa S.G.
Ale-Rocha, Rosaly
Rocha, Rosana M. da
Tidon, Rosana
Brito, Rosangela
Pellens, Roseli
Santos, Sabrina R. dos
Santos, Sandra D. dos
Paiva, Sandra V.
Santos, Sandro
Oliveira, Sarah S. de
Costa, Sávio C.
Gardner, Scott L.
Leal, Sebastián A. Muñoz
Aloquio, Sergio
Bonecker, Sergio L.C.
Bueno, Sergio L. de S.
Almeida, Sérgio M. de
Stampar, Sérgio N.
Andena, Sérgio R.
Posso, Sergio R.
Lima, Sheila P.
Gadelha, Sian de S.
Thiengo, Silvana C.
Cohen, Simone C.
Brandão, Simone N.
Rosa, Simone P.
Ribeiro, Síria L.B.
Letana, Sócrates D.
Santos, Sonia B. dos
Andrade, Sonia C.S.
Dávila, Stephane
Vaz, Stéphanie
Peck, Stewart B.
Christo, Susete W.
Cunha, Suzan B.Z.
Gomes, Suzete R.
Duarte, Tácio
Madeira-Ott, Taís
Marques, Taísa
Roell, Talita
Lima, Tarcilla C. de
Sepulveda, Tatiana A.
Maria, Tatiana F.
Ruschel, Tatiana P.
Rodrigues, Thaiana
Marinho, Thais A.
Almeida, Thaís M. de
Miranda, Thaís P.
Freitas, Thales R.O.
Pereira, Thalles P.L.
Zacca, Thamara
Pacheco, Thaynara L.
Martins, Thiago F.
Alvarenga, Thiago M.
Carvalho, Thiago R. de
Polizei, Thiago T.S.
McElrath, Thomas C.
Henry, Thomas
Pikart, Tiago G.
Porto, Tiago J.
Krolow, Tiago K.
Carvalho, Tiago P.
Lotufo, Tito M. da C.
Caramaschi, Ulisses
Pinheiro, Ulisses dos S.
Pardiñas, Ulyses F.J.
Maia, Valéria C.
Tavares, Valeria
Costa, Valmir A.
Amaral, Vanessa S. do
Silva, Vera C.
Wolff, Vera R. dos S.
Slobodian, Verônica
Silva, Vinícius B. da
Espíndola, Vinicius C.
Costa-Silva, Vinicius da
Bertaco, Vinicius de A.
Padula, Vinícius
Ferreira, Vinicius S.
Silva, Vitor C.P. da
Piacentini, Vítor de Q.
Sandoval-Gómez, Vivian E.
Trevine, Vivian
Sousa, Viviane R.
Sant’Anna, Vivianne B. de
Mathis, Wayne N.
Souza, Wesley de O.
Colombo, Wesley D.
Tomaszewska, Wioletta
Wosiacki, Wolmar B.
Ovando, Ximena M.C.
Leite, Yuri L.R.








ABSTRACT The limited temporal completeness and taxonomic accuracy of species lists, made available in a traditional manner in scientific publications, has always represented a problem. These lists are invariably limited to a few taxonomic groups and do not represent up-to-date knowledge of all species and classifications. In this context, the Brazilian megadiverse fauna is no exception, and the Catálogo Taxonômico da Fauna do Brasil (CTFB) (http://fauna.jbrj.gov.br/), made public in 2015, represents a database on biodiversity anchored on a list of valid and expertly recognized scientific names of animals in Brazil. The CTFB is updated in near real time by a team of more than 800 specialists. By January 1, 2024, the CTFB compiled 133,691 nominal species, with 125,138 that were considered valid. Most of the valid species were arthropods (82.3%, with more than 102,000 species) and chordates (7.69%, with over 11,000 species). These taxa were followed by a cluster composed of Mollusca (3,567 species), Platyhelminthes (2,292 species), Annelida (1,833 species), and Nematoda (1,447 species). All remaining groups had less than 1,000 species reported in Brazil, with Cnidaria (831 species), Porifera (628 species), Rotifera (606 species), and Bryozoa (520 species) representing those with more than 500 species. Analysis of the CTFB database can facilitate and direct efforts towards the discovery of new species in Brazil, but it is also fundamental in providing the best available list of valid nominal species to users, including those in science, health, conservation efforts, and any initiative involving animals. The importance of the CTFB is evidenced by the elevated number of citations in the scientific literature in diverse areas of biology, law, anthropology, education, forensic science, and veterinary science, among others.
5.
Formation of hydrophilic fibers containing polyhexamethylene biguanide and hyaluronic acid by electrospinning to wound healing
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Lima, Lonetá Lauro
; Rigon, Roberta Balansin
d’Ávila, Marcos Akira
Oliveira, Pedro Gonçalves de
Rezende, Rodrigo Alvarenga
Leonardi, Gislaine Ricci

Abstract For good wound management, simultaneous phases during the wound healing process must be considered, including protection against infection, modulation of the inflammatory process, and proliferation and acceleration of cell migration. The aim of this study was to obtain Poly (Vinyl Pyrrolidone) (PVP) hydrophilic fibers containing polyhexamethylene biguanide (PHMB) and hyaluronic acid (HA) using the electrospinning technique to improve chronic wound treatment. Polymers mean hydrodynamic radius and polydispersity index (PdI) were measured by dynamic light scattering (DLS), whereas fiber morphology and diameter were evaluated by scanning electron microscopy (SEM). Also, Fourier transform infrared spectroscopy (FTIR) and contact angle measurements were performed. Fibers were obtained and presented homogenous morphology with a smooth surface. The FTIR study demonstrated an interaction between C=O groups of PVP and HA/PHMB in the PVP + HA/PHMB fibrous composites. Contact angle analysis has shown a hydrophilic characteristic of fibers produced. These findings demonstrate the great potential of electrospinning for developing drug-delivery systems with antimicrobial properties for wound healing treatment.
6.
A infância e a adolescência na política de saúde mental: uma análise por meio dos conselheiros e conferências de saúde
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Abstract This qualitative, descriptive, and exploratory documentary and field research aimed to analyze how children and adolescents are included in the formulation of public mental health policies. The document analysis database consisted of reports from Health Conferences (national, state, and municipal), minutes of meetings of the Health Council (national, state, and municipal), and memories of the Thematic Commission on Mental Health (state and municipal). Nine counselors or former health counselors participated in this study through an individual interview with a semi-structured script. Furthermore, the theoretical framework for the analysis of this research was based on the communicative action of Jürgen Habermas. The themes that emerged from the documentary research included the guidelines for intersectoral processes, as well as the expansion of beds for children and adolescents. In addition, the interviews indicated the lack of discussion on the subject, predominance of the punitive perspective, and need for a broader debate. The lack of intersubjective spaces for democratic listening compromises communicative action, resulting in the invisibility of children and adolescents in the policy formulation process and reduced opportunities for participation and social control.
Resumo O objetivo do trabalho foi analisar como crianças e adolescentes são contemplados nos processos de participação para a formulação das políticas públicas de saúde mental. Pesquisa qualitativa, descritiva e exploratória de caráter documental e de campo. A base de dados da análise documental consistiu em: relatórios das Conferências de Saúde (nacional, estadual e municipal), atas de reuniões do Conselho de Saúde (nacional, estadual e municipal) e memórias da Comissão Temática de Saúde Mental (estadual e municipal). Participaram deste estudo nove conselheiros ou ex-conselheiros de saúde, por meio de uma entrevista individual com roteiro semiestruturado. Como marco teórico de análise desta pesquisa, foi proposto o agir comunicativo de Jürgen Habermas. Dentre os temas que emergiram da pesquisa documental, encontram-se as diretrizes de processos intersetoriais, bem como a ampliação de leitos para crianças e adolescentes. As entrevistas apontaram a falta de discussão da temática, predomínio da perspectiva punitivista e para a necessidade de um debate mais amplo. A falta de espaços intersubjetivos de escuta democrática compromete o agir comunicativo, ocasionando a invisibilização da criança e do adolescente no processo de formulação da política e enfraquecendo os espaços de participação e controle social.
7.
Economic analysis of the harvest date effects on quality and productivity of ‘Fuji Suprema’ apples
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Argenta, Luiz Carlos
; Anese, Rogerio de Oliveira
; Thewes, Fabio Rodrigo
; Vieira, Marcelo José
; Alvarenga, Tiago Henrique de Paula
; Freitas, Sérgio Tonetto de
; Argenta, Luiza Helena Machado
.







Abstract This study aimed to analyze the effect of harvest date on ‘Fuji Suprema’ apple quality, productivity, and economic profitability at harvest and after storage. Apples were harvested at the beginning of the commercial harvest window (H1), ten days after H1 (H2), and 22 days after H1 (H3) in the 2008 and 2009 growing seasons. A total of six samples with ~400 kg of fruit (~2,900 apples) each were picked at each growing season and harvest date, which were assessed at harvest (six subsamples of 100 fruit) and after 250 days of controlled atmosphere storage at 0.8 °C. The economic analysis considered fixed and variable production costs in the orchard and postharvest practices and the productivity of packaged apples (pack-out). Early harvested (H1) apples had greater flesh firmness, acidity, and lower soluble solids content than late-harvested apples (H3), both at harvest and after storage. Delaying harvest by 22 days increased the production by 10.2% due to increased fruit size but reduced the production by 3.6% due to severe sunburn and pre-harvest decay incidence. Late harvest also increased production losses due to decay by 4.4% and 10.9% during storage and shelf, respectively, but reduced production losses due to superficial scald by 17.1 to 22.7%. The net revenue (R$ ha-1) is higher for apples harvested late (H3, flesh firmness of 15.6 lb and starch index of 7.1) than for apples harvested early (H1 and H2) when the fruit is marketed soon after harvest (between April and May). However, for apples marketed after long-term storage, economic profitability is maximum when harvested at an intermediate maturity stage (H2, flesh firmness of 16.4 lb and starch index of 6).
Resumo Este estudo foi conduzido para analisar o impacto da época de colheita (C) de maçãs‘Fuji Suprema’ sobre sua qualidade, produtividade e rentabilidade econômica nacolheita e após a armazenagem. Os frutos foram colhidos no início do período decolheita comercial(H1), após 10 dias (C2) e após 22 dias (C3) da primeira colheita, em 2008 e2009. Em cada ano e data de colheita, foram colhidas seis amostras de ~400 kg (~2.900maçãs), as quais foram analisadas na colheita (6 subamostras de 100 maçãs) e após 250 dias de armazenagem a 0,8 oC, sob atmosfera controlada. A análise econômica considerou custos fixos e variáveis de produção no pomar e das práticas pós-colheita e a produtividadede maçãs empacotadas. As maçãs colhidas precocemente apresentaram, na colheita e após aarmazenagem, maior firmeza da polpa, maior acidez e menor teor de açúcares que as colhidas tardiamente. O atraso da colheita em 22 dias aumentou a produção em 10,2% pelo aumento do tamanho dos frutos, mas reduziu a produção em 3,6% por queimadura de solsevera e podridões pré-colheita. Adicionalmente, a colheita tardia resultou em aumentodas perdas de produção por podridões em 4,4% e 10,9% durante armazenagem e prateleira,respectivamente,e reduziu as perdas de produção por escaldadura superficial em 17,1 a 22,7%. A análise econômica mostrou que a receita líquida (R$ ha-1) é maior para maçãs colhidas tardiamente (C3, firmeza da polpa de 15,6 lb e índice de amido 7,1) que paramaçãs colhidas precocemente (H1 e C2), quando comercializadas logo após a colheita.Entretanto, para maçãs comercializadas após longos períodos de armazenagem, a rentabilidade econômica é máxima quando colhidas em estádio de maturação intermediário (C2, firmeza dapolpa de 16,4 lb e índice de amido 6).
8.
Daseinsanalyse psiquiátrica, fenomenologia das psicoses e ética da alteridade
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Revista Latinoamericana de Psicopatologia Fundamental
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Resumos This article aims to analyze the ethical aspect of the phenomenology of psychoses established by Ludwig Binswanger’s psychiatric Daseinsanalyse, based on the way Merleau-Ponty conceives the experience of others as intercorporeity. Initially, the relationship between psychiatry and phenomenology is presented, considering Binswanger’s perspective on the problem of scientific objectivity in the clinical field and his quest to develop an approach based on intersubjectivity. Finally, we tried to make some notes about the possible meaning of the approximation between phenomenology and psychiatry, in order to make possible a phenomenology of psychoses that is constituted by the recognition of alterity.
Este artículo tiene como objetivo realizar un análisis del aspecto ético de la fenomenología de las psicosis establecida por el Daseinsanalyse psiquiátrico de Ludwig Binswanger, a partir de cómo Merleau-Ponty concibe la experiencia del otro como intercorporeidad. Inicialmente, se presenta la relación entre psiquiatría y fenomenología teniendo en cuenta la perspectiva de Binswanger sobre el problema de la objetividad científica en el campo clínico y su búsqueda por desarrollar un enfoque basado en la intersubjetividad. Por último, se intenta hacer algunos apuntes sobre el posible significado de la aproximación entre fenomenología y psiquiatría para posibilitar una fenomenología de las psicosis que se constituya en el reconocimiento de la alteridad.
Cet article analyse la dimension éthique de la phénoménologie des psychoses établie par la Daseinsanalyse psychiatrique de Ludwig Binswanger, basée sur la manière dont Merleau-Ponty conçoit l’expérience d’autrui comme intercorporéité. Dans un premier temps, nous présentons la relation entre la psychiatrie et la phénoménologie, en considérant la perspective de Binswanger sur le problème de l’objectivité scientifique dans le domaine clinique et sa quête pour développer une approche basée sur l’intersubjectivité. Enfin, nous essayons quelques remarques sur le sens possible du rapprochement entre phénoménologie et psychiatrie, afin de rendre possible une phénoménologie des psychoses qui soit constituée par la reconnaissance de l’altérité.
Este artigo tem por objetivo analisar o aspecto ético da fenomenologia das psicoses estabelecida pela Daseinsanalyse psiquiátrica de Ludwig Binswanger, a partir do modo como Merleau-Ponty concebe a experiência de outrem enquanto intercorporeidade. Inicialmente se apresenta a relação entre psiquiatria e fenomenologia, considerando a perspectiva de Binswanger sobre o problema da objetividade científica no campo da clínica e sua busca por desenvolver uma abordagem fundada na intersubjetividade. Ao final, procurou-se realizar alguns apontamentos sobre o sentido possível da aproximação entre fenomenologia e psiquiatria, de modo a tornar possível uma fenomenologia das psicoses que se constitua pelo reconhecimento da alteridade.
9.
Endoscopic ultrasound-guided biliary drainage: a literature review ultrasoundguided ultrasound guided drainage
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DA-SILVA, RODRIGO RODA RODRIGUES
; MAFRA, LUCAS GALLO DE ALVARENGA
; BRUNALDI, VITOR OTTOBONI
; ALMEIDA, LETÍCIA FRANÇA DE
; ARTIFON, EVERSON LUIZ DE ALMEIDA
.





RESUMO Neoplasias da confluência biliopancreática podem cursar com obstrução da via biliar, levando a icterícia, prurido e colangite. Nesses casos a drenagem da via biliar é imperativa. A colangiopancreatografia endoscópica retrógrada (CPER) com colocação de prótese coledociana constitui tratamento eficaz em cerca de 90% dos casos mesmo em mãos experientes. Nos casos de insucesso da CPER, tradicionalmente as opções terapêuticas incluem a derivação cirúrgica por hepaticojejunostomia (HJ) ou drenagem percutânea transparietohepática (DPTH). Nos últimos anos as técnicas endoscópicas ecoguiadas de drenagem biliar ganharam espaço por serem menos invasivas, eficazes e apresentarem incidência aceitável de complicações. A drenagem endoscópica ecoguiada da via biliar pode ser realizada pelo estômago (hepatogastrostomia), duodeno (coledocoduodenostomia) ou pela técnica de drenagem anterógrada. Alguns serviços consideram a drenagem ecoguiada da via biliar o procedimento de escolha no caso de insucesso da CPER. O objetivo desta revisão é apresentar os principais tipos de drenagem biliar endoscópica ecoguiada e confrontá-los com outras técnicas. icterícia colangite imperativa CPER (CPER 90 experientes HJ (HJ DPTH. DPTH . (DPTH) invasivas complicações hepatogastrostomia, hepatogastrostomia , (hepatogastrostomia) coledocoduodenostomia (coledocoduodenostomia anterógrada confrontálos confrontá los 9 (DPTH (hepatogastrostomia
ABSTRACT Neoplasms of the biliopancreatic confluence may present with obstruction of the bile tract, leading to jaundice, pruritus and cholangitis. In these cases drainage of the bile tract is imperative. Endoscopic retrograde cholangiopancreatography (ERCP) with placement of a choledochal prosthesis is an effective treatment in about 90% of cases, even in experienced hands. In cases of ERCP failure, therapeutic options traditionally include surgical bypass by hepaticojejunostomy (HJ) or percutaneous transparietohepatic drainage (DPTH). In recent years, endoscopic ultrasound-guided biliary drainage techniques have gained space because they are less invasive, effective and have an acceptable incidence of complications. Endoscopic echo-guided drainage of the bile duct can be performed through the stomach (hepatogastrostomy), duodenum (choledochoduodenostomy) or by the anterograde drainage technique. Some services consider ultrasound-guided drainage of the bile duct the procedure of choice in the event of ERCP failure. The objective of this review is to present the main types of endoscopic ultrasound-guided biliary drainage and compare them with other techniques. jaundice cholangitis imperative (ERCP 90 hands failure HJ (HJ DPTH. DPTH . (DPTH) years ultrasoundguided ultrasound guided invasive complications echoguided echo hepatogastrostomy, hepatogastrostomy , (hepatogastrostomy) choledochoduodenostomy (choledochoduodenostomy technique 9 (DPTH (hepatogastrostomy
10.
Comparação das alterações angiográficas entre pacientes diabéticos e não diabéticos com doença arterial periférica
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Trainotti, Giovanni Ortale
; Mariúba, Jamil Victor
; Bertanha, Matheus
; Sobreira, Marcone Lima
; Yoshida, Ricardo de Alvarenga
; Jaldin, Rodrigo Gibin
Camargo, Paula Angeleli Bueno de
Yoshida, Winston Bonetti





Abstract Background Diabetics are at 5-15 times greater risk of developing peripheral arterial disease (PAD) and few studies have compared risk factors and distribution and severity of arterial changes in diabetics compared with non-diabetics. Objectives To compare angiographic changes between diabetic and non-diabetic patients with advanced PAD and correlate them with risk factors. Methods A retrospective cross-sectional study was conducted of consecutive patients undergoing lower limb arteriography for PAD (Rutherford 3-6) using TASC II and Bollinger et al. angiographic scores. Exclusion criteria were upper limb angiographies, unclear images, incomplete laboratory test results, and previous arterial surgeries. Statistical analyses included chi-square tests, Fisher's test for discrete data, and Student’s t test for continuous data (significance level: p < 0.05). Results We studied 153 patients with a mean age of 67 years, 50.9% female and 58.2% diabetics. A total of 91 patients (59%) had trophic lesions (Rutherford 5 or 6) and 62 (41%) had resting pain or limiting claudication (Rutherford 3 and 4). Among diabetics, 81.7% were hypertensive, 29.4% had never smoked, and 14% had a history of acute myocardial infarction. According to the Bollinger et al. score, infra-popliteal arteries were more affected in diabetics, especially the anterior tibial artery (p = 0.005), while the superficial femoral artery was more affected in non-diabetics (p = 0.008). According to TASC II, the most severe angiographic changes in the femoral-popliteal segment occurred in non-diabetic patients (p = 0.019). Conclusions The most frequently affected sectors were the infra-popliteal sectors in diabetics and the femoral sector in non-diabetics.
Resumo Contexto Os diabéticos possuem risco de 5 a 15 vezes maior para o desenvolvimento de doença arterial periférica (DAP), e poucos estudos compararam fatores de risco e a distribuição e gravidade de alterações arteriais angiográficas entre diabéticos e não diabéticos. Objetivos Comparar alterações angiográficas entre pacientes diabéticos e não diabéticos com DAP avançada, correlacionando-as com demais fatores de risco. Métodos Trata-se de um estudo transversal retrospectivo de pacientes consecutivos submetidos a arteriografia de membros inferiores por DAP (Rutherford de 3 a 6), usando os escores angiográficos TASC II e de Bollinger et al. Os critérios de exclusão incluíram arteriografias de membros superiores, exames incompletos ou sem nitidez e cirurgias prévias. A análise estatística incluiu o teste do qui-quadrado ou exato de Fisher para variáveis discretas e o teste t para variáveis contínuas (significância: p < 0,05). Resultados Foram estudados 153 pacientes com idade média de 67 anos, sendo 50,9% do sexo feminino e 58,2% diabéticos. Um total de 91 pacientes (59%) tinha lesão trófica (Rutherford 5 ou 6), enquanto 62 (41%) tinham dor em repouso ou claudicação limitante (Rutherford 3 e 4). Entre os diabéticos, 81,7% eram hipertensos, 29,4% nunca fumaram e 14% tinham antecedente de infarto do miocárdio. Pelo escore de Bollinger et al., as artérias infrapoplíteas foram as mais comprometidas, em especial a tibial anterior (p = 0,005) nos diabéticos, enquanto a femoral superficial foi mais acometida nos não diabéticos (p = 0,008). Pelo TASC II, as alterações arteriográficas mais graves ocorreram no segmento fêmoro-poplíteo nos pacientes não diabéticos (p = 0,019). Conclusões Os setores infrapoplíteos foram os mais comprometidos nos diabéticos, enquanto o setor femoral foi o mais acometido nos não diabéticos.
11.
Use of glass waste in the production of metakaolin-based geopolymer submitted to room temperature and thermal curing
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Alvarenga, Cristiane do Bom Conselho Sales
; Sales, Rosemary do Bom Conselho
; Caldas, Rodrigo Barreto
; Cetlin, Paulo Roberto
; Aguilar, Maria Teresa Paulino
.





Resumo O metacaulim é a principal matéria-prima utilizada na síntese de geopolímeros, embora a relação entre os teores de sílica e alumina não seja a ideal. Normalmente, o teor de SiO 2 é ajustado com o uso de silicatos presentes na solução ativadora. Uma opção ecoeficiente seria o uso de resíduos de vidro como fonte adicional de sílica. Este trabalho avalia a eficiência da ativação alcalina do metacaulim, utilizando hidróxido e silicato de potássio, com e sem substituição de 12,5% de metacaulim por micropartículas de vidro. A eficiência da ativação alcalina foi avaliada por difratometria de raios x, espectroscopia na região infravermelha com transformada de Fourier, espectroscopia de ressonância magnética nuclear do 27 Al e 29 Si, massa específica e resistência à compressão. Os resultados indicam a ocorrência de geopolimerização com e sem uso de resíduo de vidro. Observou-se que a substituição de 12,5% favorece o desempenho mecânico dos compósitos aos 28 dias, com aumentos de 37% e 47% da resistência mecânica do material com cura em estufa e na temperatura ambiente, respectivamente.
Abstract Metakaolinis the principal raw material utilized in the synthesis of geopolymers, although its ratio of silica and alumina contents is not ideal. Normally, the SiO2 content is adjusted with the use of silicates present in the activating solution. An eco-efficient alternative would be the use of glass waste as an additional source of silica.This work evaluates the efficiency of the alkaline activation of metakaolin, using potassium hydroxide and silicate, with and without the substitution of 12.5% of metakaolin by microparticles of glass. The efficiency of the alkaline activation was evaluated by X ray diffractometry, spectroscopy in the infrared region with the Fourier transform, nuclear magnetic resonance spectroscopy of 27Al and 29Si, specific mass and compressive strength. The results indicate the occurrence of geopolymerization with and without the use of glass waste. It was observed that the substitution of 12.5% favors the mechanical performance of the compounds at 28 days, with increases by 37% and 47% in the mechanical strength of the material with thermal curing and ambient temperature curing, respectively.
https://doi.org/10.1590/s1678-86212022000100584
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12.
Evaluación biológica in vitro del extracto etanólico de Kaa tái, Polygonum punctatum Elliot. (POLYGONACEAE)
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Benítez-Apodaca, Fátima
; Portillo-Torales, Nilda Elizabeth
; Alvarenga-Torres, Eliana Andrea
; López-Arias, Tomás Rodrigo
; Cáceres, Yessica
; Galeano-Chena, Mario Ricardo
; Riveros-Maidana, Rocío Lucía Beatriz
; Laterza, María Eugenia
; Bertoni, Bonifacia Benítez-de
; Yaluff, Gloria









Memorias del Instituto de Investigaciones en Ciencias de la Salud
- Journal Metrics
ABSTRACT In Paraguay, as well as in the Americas, leishmaniasis constitutes one of the important public health problems, due to its epidemiological, clinical, and biological complexity, especially affecting the poorest and developing countries. Polygonum punctatum Elliot belongs to the Polygonaceae family, and popular medicine attributes several properties to it. Previous studies confirmed that different extracts of this plant have antibacterial, anti-inflammatory and antifungal activity. In this work, the cytotoxic activity of the ethanolic extract of Polygonum punctatum was evaluated at concentrations of 100, 50 and 25 µg/ml in mouse macrophage cells, in which no cytotoxic activity was found. In addition, the leishmanicidal activity was evaluated through experimental in vitro studies at concentrations 100, 75, 50, 25, 20 and 10 µg/ml against three strains of parasites: Leishmania infantum, L. amazonensis and L. braziliensis. Activities of 58 and 56% of parasite lysis were observed with the 100 µg/ml extract against strains of L. braziliensis and L. infantum, respectively, and 51% for L. amazonensis. These results are promising and provide a basis for the development and search of a new treatment for leishmaniasis. However, further studies are necessary regarding the isolation and identification of the compound and its evaluation in in vivo animal models.
RESUMEN En Paraguay, así como en las Américas, la leishmaniasis constituye una de las problemáticas de salud pública importante, debido a su complejidad tanto epidemiológica, clínica y biológica, afectando especialmente a los más pobres y en los países en vía de desarrollo. Polygonum punctatum Elliot. pertenece a la familia Polygonaceae, la medicina popular le atribuye varias propiedades, por medio de estudios anteriores se confirma que diferentes extractos de esta planta presentan actividad antibacteriana, antiinflamatoria y antifúngica. En este trabajo, se evaluó la actividad citotóxica del extracto etanólico de Polygonum punctatum de la familia Polygonaceae en concentraciones de 100, 50 y 25 µg/ml en células de macrófagos de ratones, en los cuales no se encontró actividad citotóxica. Además, se evaluó la actividad leishmanicida por medio de estudios experimentales in vitro a concentraciones de 100, 75, 50, 25, 20 y 10 µg/ml frente a tres cepas de parásitos: Leishmania infantum, L. amazonensis y L. braziliensis, en los cuales se observó una actividad de 58 y 56% de lisis de parásitos con el extracto de 100µg/ml frente a las cepas de L. braziliensis y L. infantum, respectivamente y 51% para L. amazonensis. Estos resultados son prometedores, y aportan una base para el desarrollo y búsqueda de nuevos tratamientos para la leishmaniasis, sin embargo, son necesarios estudios posteriores en cuanto a aislamiento e identificación del compuesto y evaluación en modelos animales in vivo.
13.
The Efficiency of Railways Specialized in Transporting Iron Ore and Pellets
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RESUMO Objetivo: objetiva-se comparar a eficiência relativa das ferrovias especializadas em transporte de minério de ferro (MFe) e pelota (PLMFe), que fazem parte do patrimônio das empresas de mineração e usinas de pelotização considerando o cenário de 2016. Métodos: foi utilizada a técnica análise envoltória de dados (DEA), com aplicação do modelo de retornos constantes de escala (CCR) e orientação à saída (output); o método multicritério combinatório inicial para escolha das variáveis de entrada e a regressão Tobit como estratégia de validação do modelo DEA. Resultados: das doze ferrovias avaliadas, três ferrovias foram identificadas como eficientes: Estrada de Ferro Carajás, Fortescue e Mount Newman. Conclusões: o modelo aplicado foi considerado como um bom método para avaliar a eficiência das ferrovias especializadas em transporte de MFe e PLMFe, pois determinou a eficiência de cada ferrovia, sugerindo o aumento necessário na variável de saída ou ajustes nas variáveis de entrada para que as ferrovias atinjam a fronteira de eficiência. Com isso, as empresas podem utilizar os resultados deste estudo para guiar melhorias futuras para tornar suas ferrovias mais eficientes ou se manter na fronteira de eficiência.
ABSTRACT Objective: the objective is to compare the relative efficiency of the railways specialized in transporting iron ore (MFe) and pellets (PLMFe), which are part of the assets of mining companies and pellet plants considering the 2016 scenario. Methods: the methods used were the data envelopment analysis (DEA) technique, with the application of the output-oriented constant returns scale (CRS) model; the initial combinatorial multicriteria method for choosing the input variables; and Tobit regression as a validation strategy for the DEA model. Results: of the twelve railways evaluated, three railways were identified as efficient: Estrada de Ferro Carajás, Fortescue, and Mount Newman. Conclusions: the applied model was considered a good method to evaluate the efficiency of railways specialized in transporting MFe and PLMFe, as it determined the efficiency of each railway, suggesting the necessary increase in the output variable or adjustments in the input variables so that the railways reach the efficiency frontier. With that, companies can use the results of this study to guide future improvements to make their railways more efficient or maintain them on the frontier of efficiency.
14.
Schools reopening and the COVID-19 pandemic: a case study from Macaé, Rio de Janeiro, Brazil
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POZZOBON, ALLAN P. B.
; PETRY, ANA C.
; ZILBERBERG, CARLA
; BARROS, CINTIA M. DE
; NEPOMUCENO-SILVA, JOSÉ L.
; FEITOSA, NATÁLIA M.
; GOMES NETO, LUPIS R.
; RODRIGUES, BRUNO C.
; BRINDEIRO, RODRIGO M.
; NOCCHI, KEITY JAQUELINE C.V.
; MURY, FLAVIA B.
; SOUZA-MENEZES, JACKSON DE
; SILVA, MANUELA L. DA
; MEDEIROS, MARCIO JOSÉ DE
; GESTINARI, RAQUEL S.
; ALVARENGA, ALESSANDRA S. DE
; SILVA, CARINA A.O.
; SANTOS, DANIELE G. DOS
; SILVESTRE, DIEGO HENRIQUE
; SOUSA, GRAZIELE F. DE
; ALMEIDA, JANIMAYRI F. DE
; SILVA, JHENIFER N. DA
; BRANDÃO, LAYZA M.
; DRUMMOND, LEANDRO O.
; CARPES, RAPHAEL M.
; SANTOS, RENATA C. DOS
; PORTAL, TAYNAN M.
; TANURI, AMILCAR
; NUNES-DA-FONSECA, RODRIGO
.





























Abstract Since the first reported case of COVID-19 in Brazil, the public and private educational system started to close. Up to November 2020, scientific discussions about the return of schooling activities have been rarely performed by the national scientific community and police-makers. The great delay of school returning in Brazil contrasts with successful international strategies of school reopening worldwide and seems counterintuitive with the reopening of non-essential activities. Here, important issues to be considered before and during school reopening are reviewed and discussed. COVID-19 testing is essential to avoid disease spreading, but high cost of individual RT-qPCRs impairs an extensive testing strategy for school returning. To reduce costs and increase the speed of diagnosis, we tested the efficiency of a pooled-sample PCR strategy in a cohort of the educational staff in the city of Macaé/RJ, finding five asymptomatic individuals (0,66%) among the 754 people tested. Thus, a polled-sample PCR testing strategy of the educational staff might prevent infection spreading in schools at a reasonable cost. We discuss how our test strategy could be coupled with internationally recognized safety rules to allow for a safe school return and how countries from different world regions are dealing with educational activities during COVID-19 pandemic.
15.
Natural and synthetic pigments in sorghum-based diets for laying hens
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Chaves, Claudiane Aparecida Rocha
; Miranda, Diogo Alvarenga
Geraldo, Adriano
Machado, Luiz Carlos
Valentim, Jean Kaique
Garcia, Rodrigo Garófallo

ABSTRACT. The objective of this work was to evaluate the supplementation of yellow natural pigment levels based on Marigold Flower extract (2%) and yellow synthetic pigment (Carophyll Yellow 10%) in sorghum-based rations for commercial laying hens and their influence on bird performance and egg quality. A completely randomized design was adopted with 5 treatments, 6 replicates, and 5 laying hens in each repetition. The treatments evaluated were: Sorghum based diet without supplementation with pigmentant - Negative Control; 150 g t-1 of Yellow Natural Pigment feed; 300 g t-1 of yellow natural pigment feed; 450 g t-1 of yellow natural pigment feed; 25 g t-1 of yellow industrial pigment feed. The Tukey test was applied at 5% for the analysis of the variables of performance and quality of the eggs. The variables related to external and internal egg quality and poultry yield performance did not present significant results (p > 0.05). Only the variable color of the yolk obtained significance (p < 0.01), with an increase according to the number of pigments included in the diet. Sorghum can be used together supplementation of natural and synthetic pigments in the diet to improve yolk pigmentation. It is recommended to include 450g t-1 of natural marigold flower pigment feed (2%) in sorghum-based diets for better pigmentation of the yolk in place of 25 g t-1 of yellow synthetic pigmented, by improving the color of the yolk and not interfering in the productive performance of the laying hens and the quality of the eggs.
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