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ABSTRACT Objective: To report outcomes from the largest multicenter series of penile cancer patients undergoing video endoscopic inguinal lymphadenectomy (VEIL). Materials and Methods: Retrospective multicenter analysis. Authors of 21 centers from the Penile Cancer Collaborative Coalition-Latin America (PeC-LA) were included. All centers performed the procedure following the same previously described standardized technique. Inclusion criteria included penile cancer patients with no palpable lymph nodes and intermediate/high-risk disease and those with non-fixed palpable lymph nodes less than 4 cm in diameter. Categorical variables are shown as percentages and frequencies whereas continuous variables as mean and range. Results: From 2006 to 2020, 210 VEIL procedures were performed in 105 patients. Mean age was 58 (45-68) years old. Mean operative time was 90 minutes (60-120). Mean lymph node yield was 10 nodes (6-16). Complication rate was 15.7%, including severe complications in 1.9% of procedures. Lymphatic and skin complications were noted in 8.6 and 4.8% of patients, respectively. Histopathological analysis revealed lymph node involvement in 26.7% of patients with non-palpable nodes. Inguinal recurrence was observed in 2.8% of patients. 10y- overall survival was 74.2% and 10-y cancer specific survival was 84.8%. CSS for pN0, pN1, pN2 and pN3 were 100%, 82.4%, 72.7% and 9.1%, respectively. Conclusion: VEIL seems to offer appropriate long term oncological control with minimal morbidity. In the absence of non-invasive stratification measures such as dynamic sentinel node biopsy, VEIL emerged as the alternative for the management of non-bulky lymph nodes in penile cancer.

https://doi.org/10.1590/s1677-5538.ibju.2023.0065

Recovery of a degraded area using Platycyamus regnellii (Fabaceae) saplings Fabaceae (Fabaceae
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Bispo, L. F.

; Demolin-Leite, G. L.

; Fagundes, W. M.

; Abreu, A. M. S. A.

; Santos, J. M. M. dos

; Oliveira, F. M. M.

; Silva, V. J.

; Souza, T. O.

; Silva, Y. O. R.

; Amaral, F. L.

Brazilian Journal of Biology

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2023, Volume 83 elocation e278702

Abstract: En | Text: En | PDF: En

https://doi.org/10.1590/1519-6984.278702

Synthesis of Eugenol-Fluorinated Triazole Derivatives and Evaluation of Their Fungicidal Activity
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Lima, Ângela M. A.

; Paula, Wenderson T. de

; Leite, Iris C. H. L.

; Gazolla, Poliana A. R.

; Abreu, Lucas M. de

; Fonseca, Victor R.

; Romão, Wanderson

; Lacerda Jr., Valdemar

; Queiroz, Vagner T. de

; Teixeira, Róbson R.

; Costa, Adilson V.

Journal of the Brazilian Chemical Society

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oct 2022, Volume 33 N. 10 Pages 1200 - 1210

Abstract: En | Text: En | PDF: En

Eugenol (C10H12O2, 4-allyl-2-methoxyphenol) is a phenolic natural product that has several biological activities and possibilities of applications. It is herein described the synthesis of eugenol-fluorinated triazole derivatives and evaluation of their fungicidal activity. The reaction of eugenol with epichlorohydrin resulted in the preparation of (±)-2-((4-allyl-2-methoxyphenoxy)methyl)oxirane (1) in 88% yield. The azidolysis of 1 with sodium azide gave the azido-alcohol (±)-1-(4-allyl-2-methoxyphenoxy)-3-azidopropan-2-ol (2) in 94% yield. The CuAAc reaction between compound 2 and different terminal alkynes afforded a series of eleven derivatives (3a 3k) within 48-80% yield. All the synthesized compounds were characterized by infrared (IR) and nuclear magnetic resonance (1H and 13C) spectroscopies and high-resolution mass spectrometry. The in vitro inhibitory activity of the compounds on the mycelial growth of a strain of Colletotrichum sp., that causes anthracnose disease on papaya fruits, was evaluated. The best result was observed for compound 1-(4-allyl-2-methoxyphenoxy)-3-(4-(2-fluorophenyl)-1H-1,2,3-triazol-1-yl)propan-2-ol (3d) that showed a mean growth-inhibition zone of 5.10 mm in a well-diffusion assay, and may serve as a template for additional structural modifications, aiming for more potent fungicidal activity.

https://doi.org/10.21577/0103-5053.20220040

Synthesis and Anti-Chikungunya Virus (CHIKV) Activity of Novel 1,4-Naphthoquinone Sulfonamide and Sulfonate Ester Derivatives
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Pacheco, Paulo A. F.

; Gonzaga, Daniel T.

; Cirne-Santos, Cláudio C.

; Barros, Caroline S.

; Gomes, Max W. L.

; Gomes, Rafaela S. P.

; Gonçalves, Mariana C.

; Ferreira, Vitor F.

; Rabelo, Vitor W.

; Abreu, Paula A.

; Faria, Robson X.

; Resende, Gabriel O. de

; Rocha, David R. da

; Paixão, Izabel C. N. P.

; Silva, Fernando C. da

Journal of the Brazilian Chemical Society

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jun 2022, Volume 33 N. 6 Pages 556 - 569

Abstract: En | Text: En | PDF: En

Chikungunya virus (CHIKV) is a re-emerging disease caused by an alphavirus of the Togaviridae family. Since its first description in 1952, the disease has spread worldwide, affecting populations in both tropical and temperate countries. To date, there is no licensed vaccine or specific pharmacological treatment. Therefore, there is an increasing urgency in developing new antiviral drugs capable of specifically inhibiting viral replication. In the present work, we report the synthesis and antiviral activity evaluation of nineteen naphthoquinone derivatives, containing a sulfonamide or sulfonate group. Cell viability assays indicated a low toxic potential for all tested compounds and inhibitory assays against CHIKV identified five compounds with potent activity. The compounds were also evaluated for their virucidal potential, and the results demonstrated that compound 11a exhibited a virucidal effect higher than 70% in the treatment with 20 µM. Furthermore, in silico studies were performed to predict the antiviral drug targets.

https://doi.org/10.21577/0103-5053.20220010

Adaptability, stability and environmental stratification of genetically and nongenetically modified corn in the Cerrado
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Eckardt, Marcio

; Cardoso, Ila R. M.

; Silva, Núbia A. da

; Abreu, Yolanda V. de

; Afférri, Flávio S.

; Peluzio, Joenes M.

Revista Brasileira de Engenharia Agrícola e Ambiental

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jan 2022, Volume 26 N. 1 Pages 75 - 81

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO O rendimento da cultura depende da interação entre os fatores genéticos e ambientais, tornando-se necessário estudo de adaptabilidade, estabilidade e estratificação ambiental visando atenuar os efeitos desta interação. Neste sentido, visando estudar a interação cultivar x ambiente em cultivares comerciais de milho transgênico e não transgênico na região do Vale do Araguaia TO, foram realizados quatro ensaios de competição de cultivares implantados na safra 2018/19, sendo dois em Paraíso do Tocantins e dois em Palmas, com semeaduras realizadas em 05/11/2018 e 15/01/2019. O delineamento experimental, em cada ensaio, foi de blocos casualizados com 36 tratamentos, que foram dispostos em esquema fatorial 3 × 12, representados por três doses de adubação nitrogenada em cobertura (50, 100 e 150 kg de N ha-1) e por 12 cultivares comerciais, (seis transgênicos: 1CHD, 2CV, 3CV, 4CV, 5CTH, 6CDH e seis não transgênicos: 7GTH, 8GTH, 9GSH, 10GSH, 11GSH, 12GSH). Na análise estatística, cada dose de N em cada ensaio representou um ambiente distinto. A característica estudada foi a produtividade de grãos, sendo utilizados os métodos de adaptabilidade e estabilidade, bem como a técnica de estratificação ambiental. Houve resposta diferencial entre as cultivares oriundas de tecnologias transgênicas e não transgênicas. Cultivares transgênicas e não transgênicas, em sua maioria, foram mais adaptadas aos ambientes favoráveis. e desfavoráveis, respectivamente. Houve similaridade entre ambientes oriundos de locais, épocas de semeadura e doses de N, apontando para redução de ambientes em futuros trabalhos de melhoramento.

ABSTRACT Crop yield depends on interaction between genetic and environmental factors, making it essential to study adaptability, stability and environmental stratification in order to mitigate the effects of this interaction. Four experiments were conducted to assess competition between corn cultivars in the 2018/19 growing season, two in Paraíso do Tocantins and two in Palmas, with sowing performed on November 5, 2018 and January 15, 2019. Cultivar-environment interaction was analyzed in genetically modified (GM) and non-GM commercial corn cultivars in the Vale do Araguaia region of Tocantins state (TO), Brazil, A randomized block design was used for all the experiments, in 3 × 12 factorial scheme, with three doses of nitrogen fertilizer as topdressing (50, 100 and 150 kg of N ha-1) and 12 commercial cultivars (six non-GM, 1CHD, 2CV, 3CV, 4CV, 5CTH, 6CDH and six GM, 7GTH, 8GTH, 9GSH, 10GSH, 11GSH, 12GSH. For statistical analysis, the N dose in each experiment represented a different environment. The characteristic studied was grain yield, using the adaptability and stability methods as well as environmental stratification. Different responses were observed between the GM and non-GM cultivars. Most of the GM and non-GM cultivars were better adapted to favorable and unfavorable environments, respectively. All the environments exhibited similar behavior regardless of location, sowing time and the N dose used, demonstrating that fewer environments can be used in future breeding research.

https://doi.org/10.1590/1807-1929/agriambi.v26n1p75-81 83 downloads

Reusable Heterogeneous SnO2/ZnO Catalyst for Biodiesel Production from Acidified/Acid Oils
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Dall’Oglio, Daiane F.

; Garcia, Marco A. S.

; Fiorio, Jhonatan L.

; Abreu, Wiury C. de

; Pereira, Laise N. S.

; Braga, Adriano

; Moura, Edmilson M. de

; Guldhe, Abhishek

; Bux, Faizal

; Moura, Carla V. R. de

Journal of the Brazilian Chemical Society

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jan 2021, Volume 32 N. 1 Pages 182 - 193

Abstract: En | Text: En | PDF: En

A catalyst comprised of SnO2 impregnated on ZnO nanowires, which presented remarkable ability to catalyze fatty acid esterification/transesterification reactions, is reported. For optimization of reaction conditions, artificially acidified soybean oil with 10 wt.% oleic acid was used as a model feed. The optimized conditions were: 150 °C, 6 h, 5 g of oil, catalyst concentration of 5%, and methanol:oil molar ratio of 15:1. The catalyst achieved 92% of total fatty acid methyl esters (FAME) content and was used five times without the necessity of catalyst washing from one reaction to the other. Then, such conditions were applied to produce biodiesel from the oil extracted from Scenedesmus sp. microalgae; the system reached 72% of FAME content, without any previous refining or degumming process of the oil. Rietveld refinement, X-ray diffraction, elemental mapping in scanning transmission electron microscopy, X-ray photoelectron spectroscopy, and pyridine-desorption Fourier-transform infrared spectroscopy were used to characterize the material.

https://doi.org/10.21577/0103-5053.20200167 355 downloads

The effects of cataract surgery on autonomic heart rate control: a prospective cross-sectional and analytical study
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Aoki, Ricardo H.

; Bezerra, Italla Maria Pinheiro

; Almeida-Júnior, Alvaro Dantas de

; Barbosa, Renata Thaís de A.

; Valenti, Vitor E.

; Oliveira, Fernando R.

; Roque, Adriano L.

; Ferraz e Souza Júnior, Hugo Macedo

; Garner, David M.

; Raimundo, Rodrigo D.

; Abreu, Luiz Carlos de

Clinics

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2019, Volume 74 elocation e809

Abstract: En | Text: En | PDF: En

OBJECTIVES: We aimed to evaluate the effects of cataract surgery on cardiac autonomic modulation. METHODS: A cross-sectional and analytical study was conducted at the Hospital Maria Braido in the city of São Caetano do Sul, São Paulo, between 2015 and 2016. We investigated 19 patients of both sexes who were all over 50 years old; all patients had a diagnosis of senile or bilateral cataracts and were recommended to undergo implantation of the intraocular lens. Heart rate variability (HRV) was evaluated before, during and after cataract surgery. RESULTS: There were no significant changes in the time and geometric domains of HRV before, during or after surgery. The high-frequency (HF) band in normalized units (nu) on the spectral analysis significantly increased (p=0.02, Cohen’s d=0.9, large effect size). However, the low-frequency (LF) band in nu significantly decreased during surgery (p=0.02, Cohen’s d=0.9, large effect size). CONCLUSION: Throughout the intraocular lens implantation cataract surgery, there was an increase in parasympathetic modulation and a decrease in the sympathetic component of the heart rate (HR). We propose that this result is attributable to the supine position of the patients during surgery and the trigeminal reflex.

https://doi.org/10.6061/clinics/2019/e809 715 downloads

CHEMICAL POTENTIALS OF HARD-CORE MOLECULES BY A STEPWISE INSERTION METHOD
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Maciel, Jéssica C. da S. L.

; Abreu, Charlles R. A.

; Tavares, Frederico W.

Brazilian Journal of Chemical Engineering

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jun 2018, Volume 35 N. 2 Pages 277 - 288

Abstract: En | Text: En | PDF: En

ABSTRACT A molecular simulation algorithm was implemented to calculate chemical potentials of hard-core molecular systems at high densities. The method is based on the Widom particle insertion method and the step-function character of free energy variations. The algorithm was evaluated for hard-sphere mixtures at infinite dilution approximation by varying the solute/solvent diameter ratio, for systems with reduced densities from 0.1 to 0.8. The proposed methodology was verified by comparing simulations of trimers diluted in spheres and of single-component dimer systems with results from the literature. Then, the method was applied to mixtures of hard-spheres and dimers at several conditions regarding composition, reduced density, and bond-length/diameter ratio. The results were used to validate equations of state from the literature. The proposed approach was able to obtain accurate chemical potentials for different hard-core molecular mixtures. Lower uncertainties were obtained when comparing with traditional methods, especially at high densities.

https://doi.org/10.1590/0104-6632.20180352s20160276 1227 downloads

Primary cardiac angiosarcoma: case report of a rare neoplasia
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Abreu, Gabriela C.

; Gontijo, Maria Clara R.

; Chaves, Maria Clara L.

; Drumond, Júlia W.

; Marino, Bárbara C. A.

; Bernardes, Rodrigo C.

; Cobucci, Alexandre

; Berenstein, Cynthia K.

Jornal Brasileiro de Patologia e Medicina Laboratorial

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oct 2017, Volume 53 N. 5 Pages 320 - 324

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Este artigo ilustra um caso de angiossarcoma primário cardíaco acompanhado de uma revisão dessa rara neoplasia. Relatamos o caso de um paciente do sexo masculino, 44 anos, com suspeita de mixoma em átrio direito. O tumor, ao exame anatomopatológico, mostrou tratar-se de um angiossarcoma cardíaco. No pós-operatório, o paciente cursou com tamponamento cardíaco, necessitando ser reoperado e evoluindo a óbito. Angiossarcomas são tumores malignos caracterizados por curso clínico devastador. Apresentam predileção pelo átrio direito, e ocorrem entre a terceira e a quinta década de vida, com preponderância no sexo masculino. Devido a sua raridade, o tratamento ideal ainda não está bem estabelecido.

ABSTRACT This article reports a case of primary cardiac angiosarcoma and a brief review is provided. A 44-year-old male patient was suspected of having myxoma in the right atrium. The tumor, on pathology examination, was shown to be a cardiac angiosarcoma. In the postoperative period, the patient developed a cardiac tamponade, requiring reoperation and evolving to death. Angiosarcomas are malignant tumors characterized by a devastating clinical course. They have a predilection for the right atrium, occurring between the third and fifth decades of life, with a male preponderance. Because of its rarity, the ideal treatment has not been identified yet.

https://doi.org/10.5935/1676-2444.20170051 1233 downloads

10.

Simultaneous optimization of coffee quality variables during storage
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Abreu, Giselle F. de

; Rosa, Sttela D. V. F. da

; Cirillo, Marcelo A.

; Malta, Marcelo R.

; Clemente, Aline C. S.

; Borém, Flávio M.

Revista Brasileira de Engenharia Agrícola e Ambiental

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jan 2017, Volume 21 N. 1 Pages 56 - 60

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Objetivou-se utilizar a metodologia de resposta simultânea aplicada a um delineamento experimental para determinar a melhor combinação de tempo e das condições de armazenamento para a conservação de grãos de café. Frutos de Coffea arabica L. foram colhidos no estádio de maturação cereja, processados por via úmida ou por via seca e secados até atingir 11% de teor de água. Parte dos grãos foi beneficiada e parte não foi beneficiada antes de ser armazenada em duas condições de ambiente: em ar refrigerado a 10 ºC e umidade relativa de 50% e em 25 ºC sem controle da umidade relativa do ar. Nos períodos de 3, 6 e 12 meses, foram retiradas amostras para avaliação da qualidade. Os dados foram submetidos à técnica de otimização de resposta simultânea para cada processamento e beneficiamento separadamente, em delineamento inteiramente casualizado e esquema fatorial 2 x 3 (duas condições de armazenamento e três períodos de armazenamento). Conclui-se que a utilização da metodologia de resposta simultânea é viável para ser aplicada para determinação das condições ideais de armazenamento em condição refrigerada.

ABSTRACT The objective of the study was to use methodology of simultaneous optimization of multiple responses applied to an experimental design to determine the best combination of storage period and conditions for preservation of coffee beans. Coffea arabica L. fruits were harvested in the ripe stage of maturation, processed using wet and dry methods, and dried to 11% (wet basis) moisture content. Part of the beans was hulled, while the other part was hulled only after the beans were stored under two different environmental conditions: cooled air at 10 ºC with 50% relative humidity; and at 25 ºC without controlling the relative humidity. Samples were taken at 3, 6, and 12 months intervals in order to evaluate quality. The data were submitted to the simultaneous optimization of responses for each processing and hulling condition separately, in a completely randomized design and 2 x 3 factorial scheme (two storage conditions and three storage periods). In conclusion, the use of the simultaneous optimization of responses is viable to be applied for determining the ideal storage conditions in a refrigerated condition.

https://doi.org/10.1590/1807-1929/agriambi.v21n1p56-60 1789 downloads

11.

Constitución subjetiva en un ambiente confiable: juego y apego
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Paolicchi, G.

; Kohan Cortada, A.

; Núñez, A. M.

; Sorgen, E.

; Colombres, R.

; Maffezzoli, M.

; Abreu, L.

Anuario de investigaciones

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dec 2015, Volume 22 N. 2 Pages 313 - 322

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

This paper presents some results of research and intervention carried out under the program UBACyT "Attitudes towards children's play and adult attachment patterns" (Scientific Program 2012-2015) that articulates with the University's Extension Program "toy libraries neighborhood". The assumed theoretical framework highlights the importance of play as an activity which has an irreplaceable value in structuring the psyche. Conceptualizations about the sequence of development of playful activity in the process of subjective constitution, the need for the "other", through the maternal function, for the deployment of the processes of symbolization and playful activities, positioning it intersubjective as logical antecedent of the subjective plot. And also, conceptualizations of attachment types that inform adults and attitudes towards children's play arise. This work includes results obtained during field research. From the quantitative approach, with standardized instruments applied, as well as from the qualitative, taking some situations fragments exposed in scenes relating to the constitution of the playful function.

El presente trabajo expone algunos resultados de investigación e intervención llevados a cabo en el marco del Programa UBACyT "Actitudes hacia el juego infantil y modalidades de apego en adultos" (Programación científica 2012-2015) que se articula con el Programa de Extensión Universitaria "Juegotecas Barriales". El marco teórico asumido resalta la importancia del juego en tanto actividad que posee un valor insustituible en la estructuración del psiquismo. Se esbozan conceptualizaciones acerca de la secuencia del desarrollo de la actividad lúdica en el proceso de constitución subjetiva, la necesidad del "otro" -a través de la función materna- para el despliegue de los procesos de simbolización y de la actividad lúdica, posicionando lo intersubjetivo como antecedente lógico de la trama subjetiva. Así como también, se plantean conceptualizaciones sobre los tipos de apego que informan los adultos y las actitudes hacia el juego infantil. Este trabajo incluye resultados obtenidos durante la investigación de campo. Desde el enfoque cuantitativo, con los instrumentos estandarizados aplicados, como también desde el cualitativo, tomando algunas situaciones expuestas en fragmentos relativos a escenas de constitución de la función lúdica.

330 downloads

12.

Perezone, from the gorgonian Pseudopterogorgia rigida, induces oxidative stress in human leukemia cells
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Abreu, Paula A.

; Wilke, Diego V.

; Araujo, Ana J.

; Marinho-Filho, José Delano B.

; Ferreira, Elthon G.

; Ribeiro, Carlos Margo R.

; Pinheiro, Leandro S.

; Amorim, Juliana W.

; Valverde, Alessandra L.

; Epifanio, Rosângela A.

; Costa-Lotufo, Letícia V.

; Jimenez, Paula C.

Revista Brasileira de Farmacognosia

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dec 2015, Volume 25 N. 6 Pages 634 - 640

Abstract: En | Text: En | PDF: En

Abstract Four bisabolanes 1–4, including perezone (1) and triacetyl perezone (2), were isolated through a bioassay-guided fractionation of the extract obtained from the Caribbean gorgonian coral Pseudopterogorgia rigida collected during an expedition cruise to the Bahamas. All isolated compounds showed to be cytotoxic toward panel of four human tumor cell lines, as quantified by the MTT assay after 72 h incubation. Perezone (1), the most active one, was further analyzed, showing to be cytotoxic, but not selective, in a 12-cell line panel comprising tumor and non-tumor, as well as human and murine cells. Additionally, 1 was assayed for cytotoxicity against HL-60 leukemic cells. Pre-treatment with an acute free radical scavenger (L-NAC) before exposure of cells to perezone virtually eliminated the generation of intracellular ROS and lessened its severe cytotoxicity. The protective effect delivered by L-NAC evidences that the mechanism of perezone-induced cytotoxicity is partially associated to production of ROS and a consequent induction of oxidative stress.

https://doi.org/10.1016/j.bjp.2015.07.020 956 downloads

13.

Modelos de norma de reação para estudo das características de qualidade da carne de codornas de corte em função das razões (metionina + cistina): lisina da dieta
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Veloso, R. C.

; Abreu, L. R. A.

; Mota, L. F. M.

; Castro, M. R.

; Silva, M. A.

; Pires, A. V.

; Lima, H. J. D'A.

; Boari, C. A.

Arquivo Brasileiro de Medicina Veterinária e Zootecnia

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oct 2015, Volume 67 N. 5 Pages 1438 - 1448

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMOObjetivou-se avaliar a sensibilidade dos valores genéticos para características de qualidade da carne em codornas de corte alimentadas com dietas contendo diferentes relações de (metionina + cistina): lisina, do nascimento aos 21 dias de idade, por meio de modelos de normas de reação. Utilizaram-se 9011 informações de qualidade de carne referentes a 1400 progênies de 80 reprodutores e 160 matrizes de duas linhas (LF1 e LF2). Para o ajuste dos modelos de regressão aleatória, foi usado o programa WOMBAT, considerando-se nas análises homogeneidade de variância residual. As codornas foram alimentadas do nascimento aos 21 dias de idade com dietas contendo as relações 0,61; 0,66; 0,71; 0,76 e 0,81 de (metionina + cistina): lisina, mantendo os níveis de proteína bruta de 26,12% e de energia em 2900 kcal EM/kg da dieta. Dos 22 aos 35 dias de idade, todas as codornas foram alimentadas com dieta contendo 22% de proteína bruta e 3050 kcal EM/kg da dieta. As estimativas da variância genética e da herdabilidade foram influenciadas pelo gradiente ambiental e pela linha, com mudanças nessas estimativas com o aumento do gradiente ambiental. Os valores genéticos das características de qualidade de carne referentes a cada uma das linhas se alteraram com o aumento das relações de aminoácidos das dietas em razão das mudanças no ordenamento dos valores genéticos, evidenciando a existência da interação genótipo x nível de relação dos aminoácidos da dieta para características de qualidade de carne. Predições de valores genéticos de características de qualidade de carne com base em determinada relação de (metionina + cistina): lisina da dieta não são válidas para outras relações desses aminoácidos.

ABSTRACTThis study aimed to evaluate the sensitivity of breeding values for meat quality traits of European quails fed different (methionine + cystine): lysine ratio diets from hatch to 21 days of age, using reaction norm models. A total of 9011 meat quality records from 1400 progenies of 80 sires and 160 dams from two lines (LF1 and LF2) were used in the analyses considering homogeneity of residual variance. The quails from hatch to 21 days of age were fed diets containing 0.61, 0.66, 0.71, 0.76 and 0.81 (methionine + cystine): lysine ratios, 26.12% of crude protein and 2900 ME/kcal of diet. From 22 to 35 days of age all quail were fed a diet containing 22% of crude protein and 3050 kcal ME/kg of diet. The random regression model analyses was performed using the WOMBAT program considering homogeneity of residual variance. Genetic variance and heritability estimates were affected by the environment gradient of diet and line, increasing these estimates with the increase of the (methionine + cystine): lysine ratio of the diet. The breeding values changed with the increase of the environment gradient of the diet with changes in the rank of genetic breeding values characterizing the existence of genotype by environment interaction for meat quality traits. Predictions of meat quality trait breeding values based on a given (methionine + cystine): lysine ratio are not valid for other levels of the amino acid ratio.

https://doi.org/10.1590/1678-4162-7940 1768 downloads

14.

Crescimento de codornas de diferentes grupos genéticos por meio de modelos não lineares
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Mota, L. F. M.

; Alcântara, D. C.

; Abreu, L. R. A.

; Costa, L. S.

; Pires, A. V.

; Bonafé, C. M.

; Silva, M. A.

; Pinheiro, S. R. F.

Arquivo Brasileiro de Medicina Veterinária e Zootecnia

Journal Metrics
- Sobre o periódico
- SciELO Analytics

oct 2015, Volume 67 N. 5 Pages 1372 - 1380

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMOObjetivou-se com o presente trabalho ajustar modelos não lineares para descrever o padrão de crescimento de genótipos de codornas de corte e de postura do nascimento aos 35 dias de idade. Foram utilizados dados de 1280 codornas machos e fêmeas, provenientes de sete genótipos de codornas de corte (EV1, EV2, UFV1, UFV2, UFV3, LF1, LF2) e um de postura. Todas as codornas foram pesadas a cada sete dias, do nascimento aos 35 dias de idade. Foram ajustados os modelos Brody, Gompertz, Logístico, Richards e von Bertalanffy aos dados de peso corporal de todos os genótipos. As análises estatísticas foram realizadas utilizando-se o PROC NLIN do SAS (Statistical Analysis System, versão 9.0). Os critérios empregados para a escolha do melhor modelo para descrever a curva de crescimento foram o coeficiente de determinação ajustado (R2), o desvio padrão assintótico (DPA), o desvio médio absoluto dos resíduos (DMA), o índice assintótico (IA), o critério de informação bayesiano (BIC), o critério de Akaike (AIC) e o quadrado médio do erro (QME). Todos os modelos não lineares testados convergiram, com exceção do modelo Brody, que não convergiu para nenhum genótipo avaliado. O modelo Richards não convergiu para o genótipo postura. Os parâmetros da curva de crescimento estimados pelos modelos indicaram maior precocidade, em geral, do genótipo postura comparado aos demais genótipos. O modelo Richards apresentou superestimação do ponto de inflexão para todos os genótipos, exceto para o genótipo postura. Os modelos Gompertz, Logístico e von Bertalanffy são recomendados para descrever o crescimento de codornas de corte dos grupos genéticos em estudo. O modelo Brody não convergiu, por isso não é recomendado para descrever o crescimento dos grupos genéticos de codornas em estudo.

ABSTRACTThis work aimed to adjust nonlinear models to describe the growth pattern of meat type and posture quail genotypes from hatch to 35 days of age. A total of 1280 male and female quails from EV1, EV2, UFV1, UFV2, UFV3, LF1 and LF2 and Posture genotypes were weighed every seven days, from hatch to 35 days of age. Brody, Gompertz, Logistic, von Bertalanffy and Richards models were used to fit the growth of the genetic groups. Statistical analyses were performed using PROC NLIN of SAS (Statistical Analysis System, version 9.0). The criteria used to select the model showing the best goodness of fit to the growth of the genotypes were: Adjusted Coefficient of Determination (R2), Asymptotic Standard Deviation (DPA), Absolut Mean Deviation (DMA), Asymptotic Index (AI), Bayesian Information Criterion (BIC), Akaike Information Criterion (AIC) and Errors Mean Square (MSE). All nonlinear models converged for the studied genotypes, except Richard the model for the Posture genotype. In general, the estimated parameters for the growth curve using nonlinear models suggested higher precocity for the Posture genotype in comparison to meat type genotypes. The Richard model overestimates the inflection point for all genotypes, except for the Posture genotype. The Gompertz, Logistic and von Bertalanffy are recommended to describe the growth patterns of the studied quail genetic groups. The Brody model did not converge and is not recommended to describe the genetic growth of the studied groups.

https://doi.org/10.1590/1678-4162-7534 1774 downloads

15.

Normas de associação semântica para 20 categorias em adultos e idosos
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Bordignon, Suelen

; Zibetti, Murilo R.

; Trentini, Clarissa M.

; Resende, Ana Cristina

; Minervino, Carla A. S. M.

; Silva-Filho, José Humberto da

; Pawlowski, Josiane

; Teodoro, Maycoln L. M.

; Abreu, Neander

Psico-USF

Journal Metrics
- Sobre o periódico
- SciELO Analytics

apr 2015, Volume 20 N. 1 Pages 97 - 108

Abstract: Pt En Es | Text: Pt En Es | PDF: Pt | PDF: En | PDF: Es

O desenvolvimento de normas para categorias semânticas é necessário para a compreensão do modo como os indivíduos organizam o conhecimento na memória e para a construção de instrumentos de avaliação cognitiva. O objetivo do presente estudo é fornecer normas associativas de 20 categorias semânticas para adultos e idosos brasileiros. Participaram do estudo 236 pessoas, entre 40 e 88 anos, das cinco regiões brasileiras. Os participantes responderam a um questionário de dados sociodemográficos e a um questionário de itens para categorias semânticas, e foram solicitados a produzir os cinco primeiros exemplares de cada categoria apresentada. Os resultados foram agrupados e são apresentadas as normas das categorias (exemplares, tamanho da categoria, respostas corretas, em branco e erros), bem como as respostas de cada categoria que foram comuns a todas as regiões brasileiras.

The development of semantic category norms is necessary to assist in the understanding of how individuals organize knowledge in memory, and to the creation of cognitive assessment instruments. The aim of this study is to provide associative norms of 20 semantic categories for Brazilian adults and elderly. The study included 236 participants from 40 to 88 years of age from the five Brazilian regions. They answered a socio-demographic questionnaire and a semantic category questionnaire, in which they were asked to produce the first five items of each category. Results are presented in category norms (items, category set size, correct responses, no responses and errors), as well as the responses that were common to all Brazilian regions belonging to each category.

Es necesario el desarrollo de normas para categorías semánticas para poder comprender cómo las personas organizan el conocimiento en la memoria y para la construcción de instrumentos de evaluación cognitiva. El objetivo de este estudio es proporcionar normas asociativas de 20 categorías semánticas para muestras de brasileños adultos y ancianos. Participaron 236 personas entre 40 y 88 años, de cinco regiones de Brasil. Los participantes completaron un cuestionario de datos sociodemográfico y un cuestionario de ítems para categorías semánticas y se les solicitó la producción de los cinco primeros ejemplares de cada categoría presentada. Los resultados fueron agrupados y son presentadas las normas de las categorías (ejemplares, tamaño de categoría, respuestas correctas, en blanco y errores), así como las respuestas de cada categoría, comunes a todas las regiones de Brasil.

https://doi.org/10.1590/1413-82712015200109 3352 downloads

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