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Final recommendations for the Latin America and Caribbean Periodontics Consensus 2024
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VILLAR, Cristina Cunha

; CARVAJAL, Paola

; CARRER, Fernanda

; ROMITO, Giuseppe Alexandre

; COLLINS, James Rudolph

; ALARCÓN, Marco Antonio

; RÖSING, Cassiano Kuchenbecker

; CAVAGNI, Juliano

; DUQUE, Andres Duque

; LAFAURIE Villamil, Gloria Inés

; FISCHER, Ricardo Guimarães

; STEWART, Bernal

; MALHEIROS, Zilson

; BENÍTEZ, Carlos

; PANNUTI, Claudio Mendes

Brazilian Oral Research

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2024, Volume 38 Suppl. 1 elocation e122

Abstract: En | Text: En | PDF: En

Abstract The 2024 Consensus on Periodontology for Latin America and the Caribbean addresses the significant public health issue of periodontal diseases, impacting millions in the region. This comprehensive document presents holistic recommendations to standardize diagnostic methodologies, enhance public awareness, and integrate preventive and therapeutic practices into general healthcare. Key areas include understanding the prevalence and impact of periodontal diseases, identifying risk factors, and improving diagnostic, preventive, and treatment strategies. The consensus emphasizes interdisciplinary collaboration, tailored public health interventions, and the importance of continuous monitoring and research. By unifying efforts across various sectors, the consensus aims to reduce the burden of periodontal diseases, thereby improving both oral and general health outcomes in Latin America and the Caribbean.

https://doi.org/10.1590/1807-3107bor-2024.vol38.0122

Advancing with the 2024 Latin America and the Caribbean Periodontal Consensus
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PANNUTI, Claudio Mendes VILLAR, Cristina Cunha

Brazilian Oral Research

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2024, Volume 38 Suppl. 1 elocation e115

Abstract: En | Text: En | PDF: En

https://doi.org/10.1590/1807-3107bor-2024.vol38.0115

Treatment of periodontal diseases: Latin America and the Caribbean Consensus 2024
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FISCHER, Ricardo Guimarães

; AMARAL, Guilherme Castro Lima Silva do

; HUAMÁN-MENDOZA, Aldrin André

; BUENO, Luis Rossy

; VILLAR, Cristina Cunha

Brazilian Oral Research

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2024, Volume 38 Suppl. 1 elocation e121

Abstract: En | Text: En | PDF: En

Abstract The prevalence of periodontitis in Latin American and Caribbean countries (LACC) drew attention to a significant public health issue exacerbated by socio-economic disparities. This consensus report, based on the European Federation of Periodontology (EFP) S3 level clinical practice guidelines, proposed a multifaceted approach to periodontal health-care. The report highlighted the critical need for holistic, population-wide health policies and underscored the lack of documented community interventions in contemporary literature. The consensus advocated for a patient-centered approach to periodontal care, with non-surgical and surgical interventions, and a long-term commitment to supportive periodontal care (SPC). It emphasized the importance of patient engagement in biofilm control by means of home-care and professional interventions for long-term periodontal health. The report also stressed that subgingival instrumentation benefits even severely compromised teeth, by significantly reducing probing depths and gingival inflammation. Moreover, it emphasized the importance of personalized, long-term SPC for maintaining oral health post-treatment, and pointed out the need to identify factors influencing patient adherence. The aim of this report was to provide actionable guidance for clinicians and policymakers, focused on improving periodontal health outcomes and quality of life in LACC.

https://doi.org/10.1590/1807-3107bor-2024.vol38.0121

Efficacy of mouthrinses in reducing oral SARS-COV-2 load: a review SARSCOV2 SARSCOV SARS COV 2 SARS-COV- load SARS-COV
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PANNUTI, Claudio Mendes

; REIS, Isabella Neme Ribeiro dos

; SOUZA, Nathalia Vilela

; SOUTO, Maria Luisa Silveira

; SILVA, Carlos Guillermo Benítez

; BEZINELLI, Leticia Mello

; MACHADO, Clarisse Martins

; ROMITO, Giuseppe Alexandre

; VILLAR, Cristina Cunha

Brazilian Oral Research

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2023, Volume 37 elocation e038

Abstract: En | Text: En | PDF: En

Abstract Accumulated evidence has shown that the oral cavity may be an important reservoir for SARS-CoV-2. Some authors have suggested that the use of mouthrinses could reduce SARS-CoV-2 viral load in the saliva. Thus, the aim of this review was to synthesize evidence about the efficacy of mouthrinses in reducing the salivary viral load of SARS-CoV-2. 2. Nine randomized controlled trials (RCTs) have investigated the efficacy of different mouthrinses in reducing salivary SARS-CoV-2 loads. Various active ingredients have been tested in these trials: 0.5%,1% and 2% povidone-iodine, 0.2% and 0.12% chlorhexidine (CHX), 0.075% cetylpyridinium chloride (CPC), 0.075% CPC with Zinc lactate, 1% and 1.5% hydrogen peroxide (HP), 1.5% HP + 0.12% CHX and ß-cyclodextrin and citrox. The studies reported an intra-group reduction in the salivary levels of the virus, when compared with the baseline. However, the majority of these trials failed to demonstrate a significant inter-group difference between active groups and the control group relative to the decrease in salivary SARS-CoV-2 loads. Although promising, these results should be confirmed by larger trials. SARSCoV2. SARSCoV2 SARSCoV SARS CoV 2 SARS-CoV- saliva Thus RCTs (RCTs loads 051 0 5 1 0.5%,1 povidoneiodine, povidoneiodine povidone iodine, iodine povidone-iodine 02 0.2 012 12 0.12 CHX, , (CHX) 0075 075 0.075 CPC, (CPC) lactate 15 1.5 HP, (HP) ßcyclodextrin ß cyclodextrin citrox intragroup intra virus baseline However intergroup inter promising SARS-CoV 05 0.5%, 0. 01 0.1 (CHX 007 07 0.07 (CPC 1. (HP 0.5% 00 0.0 0.5

https://doi.org/10.1590/1807-3107bor-2023.vol37.0038

Toothpaste-related interests of Google users from different countries
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DI PROFIO, Bruna

; LOTTO, Matheus

; AGUIRRE, Patricia Estefania Ayala

; VILLAR, Cristina Cunha

; ROMITO, Giuseppe Alexandre

; BRAGA, Mariana Minatel

; CRUVINEL, Thiago

; PANNUTI, Cláudio Mendes

Brazilian Oral Research

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2023, Volume 37 elocation e124

Abstract: En | Text: En | PDF: En

Abstract The Internet is a growing source of knowledge and can provide information about oral health. This ecological study aimed to characterize the interests in toothpaste among Google users from different countries. Our hypothesis was that there would be an increase in Google users’ interest in information about toothpaste. This retrospective longitudinal ecological study analyzed the toothpaste-related interest of Google users from 10 countries between January 2004 and December 2020. The monthly variation in relative search volume (RSV) and the main related queries were determined using Google Trends. Autoregressive integrated moving average (ARIMA) forecasting models were built to establish the predictive RSV values for toothpaste for an additional 12 months. Autocorrelation plots and the generalized additive model (GAM) were used to diagnose trends and seasonality in RSV curves. Additionally, the influence of social isolation related to the outbreak of COVID-19 was analyzed. Although not detected by autocorrelation function (ACF) and partial autocorrelation function (PACF) analyses, the heuristic analysis showed an increase in the interest in toothpaste-related information in all countries, with a stable trend observed in the 12-month forecasts, except for the increases in the United Kingdom and South Africa. Also, GAM analyses demonstrated a non-significant monthly or quarterly seasonal influence on data. In addition, social isolation during the COVID-19 pandemic did not influence the online information-seeking behavior of Google Search users linked to this topic. We confirmed the hypothesis that the interest of Google Search users in information about toothpaste increased in all of the 10 assessed countries.

https://doi.org/10.1590/1807-3107bor-2023.vol37.0124

Periodontal diseases: is it possible to prevent them? A populational and individual approach
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COTA, Luís Otávio Miranda

; VILLAR, Cristina Cunha

; VETTORE, Mario Vianna

; CAMPOS, Julya Ribeiro

; AMARAL, Guilherme Castro Lima Silva do

; CORTELLI, José Roberto

; CORTELLI, Sheila Cavalca

Brazilian Oral Research

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2021, Volume 35 Suppl. 2 elocation e098

Abstract: En | Text: En | PDF: En

Abstract Periodontal diseases are infectious inflammatory chronic diseases of a multifactorial nature. They are primarily caused by dysbiotic ecological changes in dental biofilm, which may be influenced by risk factors. The prevention of periodontal diseases may involve different strategies focused on reducing distal, intermediate, and proximal risk factors at both the population and individual levels. Effective prevention depends on interdisciplinary and common risk factor approaches. Also, patient-centered preventive models are more effective than professional-centered models in the management of periodontal diseases. Regular and periodic control of dental biofilm is an essential measure for the different levels of prevention of periodontal diseases. The effectiveness of periodontal disease prevention largely depends on positive modifications of behavior, knowledge, health literacy, patient empowerment, motivation, and compliance.

https://doi.org/10.1590/1807-3107bor-2021.vol35.0098 161 downloads

Prevalence of horizontal alveolar changes in edentulous patients: a retrospective tomographic study
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Dias, Márcio Américo

; Romito, Giuseppe

; Villar, Cristina Cunha

; Sapata, Vitor Marques

; Teixeira, Marcelo Lucchesi

; Aloise, Antonio Carlos

; Mannina, Carolina

; Macedo, Luís Guilherme Scavone de

; Moy, Peter Karyen

; Pelegrine, André Antonio

Brazilian Oral Research

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2020, Volume 34 elocation e016

Abstract: En | Text: En | PDF: En

Abstract Horizontal bone loss after tooth extraction is a common finding that demands bone reconstruction in various cases. The aim of this study was to assess the horizontal alveolar status in partially and completely edentulous patients using cone-beam computed tomography (CBCT). In total, 1516 CBCT scans of 1404 adult patients were analyzed. Assessment of the images was performed in accordance with the previously published horizontal alveolar change (HAC) classification, which categorizes horizontal bone defects into four classes: HAC 1, HAC 2, HAC 3 and HAC 4 (from the least severe to the most severe condition). Analysis of 1048 scans from partially edentulous patients presented a distribution of 63.55%, 22.14%, 13.36% and 0.95% in HAC 1, HAC 2, HAC 3 and HAC 4, respectively. Analysis of 468 scans from completely edentulous patient images presented a distribution of 19.87%, 28.63%, 41.67% and 9.83% in HAC 1, HAC 2, HAC 3 and HAC 4, respectively. Based on these results, as in HAC 4, no cancellous bone was found between the cortical buccal and lingual/palatal bone plates, it seems reasonable to state that the absence of cancellous bone is higher in completely edentulous patients than in partially edentulous patients. Therefore, the absence of cancellous bone seems to be higher in completely edentulous than in partially edentulous patients.

https://doi.org/10.1590/1807-3107bor-2020.vol34.0016 1309 downloads

Implant-based factor as possible risk for peri-implantitis
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ZANDIM-BARCELOS, Daniela Leal

; CARVALHO, Gabriel Garcia de

; SAPATA, Vitor Marques

; VILLAR, Cristina Cunha

; HÄMMERLE, Christoph

; ROMITO, Giuseppe Alexandre

Brazilian Oral Research

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2019, Volume 33 Suppl. 1 elocation e067

Abstract: En | Text: En | PDF: En

Abstract Peri-implantitis is currently a topic of major interest in implantology. Considered one of the main reasons of late implant failure, there is an emerged concern whether implant characteristics could trigger inflammatory lesion and loss of supporting bone. The purpose of this narrative review is to provide an evidence based overview on the influence of implant-based factors in the occurrence of peri-implantitis. A literature review was conducted addressing the following topics: implant surface topography; implant location; occlusal overload; time in function; prosthesis-associated factors (rehabilitation extension, excess of cement and implant-abutment connection); and metal particle release. Although existing data suggests that some implant-based factors may increase the risk of peri-implantitis, the evidence is still limited to consider them a true risk factor for peri-implantitis. In conclusion, further evidences are required to a better understanding of the influence of implant-based factors in the occurrence of peri-implantitis. Large population-based studies including concomitant analyses of implant- and patient-based factors are required to provide strong evidence of a possible association with peri-implantitis in a higher probability. The identification of these factors is essential for the establishment of strategies to prevent peri-implantitis.

https://doi.org/10.1590/1807-3107bor-2019.vol33.0067

A systematic review and meta-analysis of the survival rate of implants placed in previously failed sites
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Gomes, Giovane Hisse Misawa, Mônica Yuri Orita Fernandes, Carolina Pannuti, Claudio Mendes Saraiva, Luciana Huynh-Ba, Guy Villar, Cristina Cunha

Brazilian Oral Research

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2018, Volume 32 elocation e27

Abstract: En | Text: En | PDF: En

Abstract The aim of this study was to conduct a systematic review and meta-analysis to assess the clinical outcomes of dental implants placed in previously early and late implant failed sites. An electronic literature search was conducted in several databases for articles published up to February 2018. Human clinical trials that received at least one implant in a previously failed site were included. Hence, the PICO question that was aimed to be addressed was: Do patients undergoing implant replacement (second and third attempts) in previous failed sites have survival rates similar to implants placed at first attempts? A random effects model was used to calculate survival weighted means and corresponding 95% Confidence Intervals (CI) among studies. Eleven studies of low to moderate methodological quality were included in this review. Implants placed in sites with history of one and two implant failures had a weighted survival rate (SR) of 88.7% (95%CI 81.7-93.3) and 67.1% (95%CI 51.1-79.9), respectively. Implants placed in sites with a previous early failure revealed a weighted SR of 91.8% (95%CI 85.1-95.6). First implants presented higher SR than implants placed in sites with one or two previous implant failures. In contrast, implants placed in sites with one and two implant failures had similar SR. Within its limitations, this review suggests that replacement implants have moderate SR. Larger prospective studies with well-defined criteria for early and late implant failure are necessary to confirm and expand on these results.

https://doi.org/10.1590/1807-3107bor-2018.vol32.0027 3782 downloads

10.

Efficacy of stem cells on bone consolidation of distraction osteogenesis in animal models: a systematic review
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MORILLO, Carlos Manuel Rubio SLONIAK, Mariane Cristina GONÇALVES, Fernanda VILLAR, Cristina Cunha

Brazilian Oral Research

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2018, Volume 32 elocation e83

Abstract: En | Text: En | PDF: En

Abstract Distraction osteogenesis (DO) relies on the recruitment and proliferation of mesenchymal stem cells (MSC) to the target site, where they differentiate into osteoblasts to promote bone formation. Nevertheless, MSC recruitment appears to be slow and limits bone formation in DO defects. Thus, this systematic review aims to evaluate the ability of locally applied MSC to enhance bone formation in DO preclinical models. Databases were searched for quantitative pre-clinical controlled studies that evaluated the effect of local administration of MSC on DO bone formation. Eligible studies were identified and data regarding study characteristics, outcome measures and quality were extracted. Nine studies met the inclusion criteria. Autogenous and xenogenous MSC were used to promote DO bone formation. These included bone marrow-derived MSC, adipose tissue-derived MSC and MSC derived from human exfoliated deciduous teeth. Meta-analysis was not possible due to heterogeneities in study designs. Local MSC implantation was not associated with adverse effects. In 4 out of the 5 studies, locally delivered undifferentiated bone-marrow MSC had a positive effect on DO bone formation. Few studies evaluated the therapeutic effects of MSC from other sources. The adjunct use of biologically active molecules or forced expression of key genes involved in osteogenesis further boosted the ability of bone-marrow MSC to promote DO bone formation. While risk of bias and heterogeneity limited the strength of this systematic review, our results suggest that the use of MSC is safe and may provide beneficial effects on DO bone formation.

https://doi.org/10.1590/1807-3107bor-2018.vol32.0083 1087 downloads

11.

Horizontal Bone Reconstruction on sites with different amounts of native bone: a retrospective study
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Pelegrine, André Antonio Romito, Giuseppe Villar, Cristina Cunha Macedo, Luís Guilherme Scavone de Teixeira, Marcelo Lucchesi Aloise, Antonio Carlos Moy, Peter Keyren

Brazilian Oral Research

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2018, Volume 32 elocation e21

Abstract: En | Text: En | PDF: En

Abstract: The lack of guidelines for bone augmentation procedures might compromise decision making in implantology. The objective of this study was to perform a retrospective study to verify the outcomes of horizontal bone reconstruction in implant dentistry with different types of materials and amounts of native bone in the recipient bed to allow for a new guideline for horizontal bone reconstruction. One hundred preoperative CT scans were retrospectively evaluated and categorized in accordance to horizontal bone defects as presence (Group P) or absence (Group A) of cancellous bone in the recipient bed. Different approaches were used to treat the edentulous ridge and the outcomes were defined either as satisfactory or unsatisfactory regarding the possibility of implant placement. The percentage distribution of the patients according to the presence or absence of cancellous bone was 92% for Group P and 8% for Group A. In Group P, 98% of the patients had satisfactory outcomes, and the use of autografts had 100% of satisfactory outcomes in this group. In Group A, 37.5% of the patients had satisfactory outcomes, and the use of autografts also yielded 100% of satisfactory outcomes. The use of allografts and xenografts in Group A had 0% and 33.3% of satisfactory outcomes, respectively. Therefore, it seems reasonable to speculate that the presence of cancellous bone might be predictive and predictable when the decision includes bone substitutes. In cases of absence of cancellous bone in the recipient bed, the use of a vitalized graft seems to be mandatory.

https://doi.org/10.1590/1807-3107bor-2018.vol32.0021 2490 downloads

12.

Fracture resistance of abutment screws made of titanium, polyetheretherketone, and carbon fiber-reinforced polyetheretherketone
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NEUMANN, Eduardo Aloisio Fleck VILLAR, Cristina Cunha FRANÇA, Fabiana Mantovani Gomes

Brazilian Oral Research

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2014, Volume 28 N. 1 Pages 1 - 5

Abstract: En | Text: En | PDF: En

Fractured abutment screws may be replaced; however, sometimes, the screw cannot be removed and the entire implant must be surgically removed and replaced. The aim of this study was to compare the fracture resistance of abutment retention screws made of titanium, polyetheretherketone (PEEK) and 30% carbon fiber-reinforced PEEK, using an external hexagonal implant/UCLA-type abutment interface assembly. UCLA-type abutments were fixed to implants using titanium screws (Group 1), polyetheretherketone (PEEK) screws (Group 2), and 30% carbon fiber-reinforced PEEK screws (Group 3). The assemblies were placed on a stainless steel holding apparatus to allow for loading at 45o off-axis, in a universal testing machine. A 200 N load (static load) was applied at the central point of the abutment extremity, at a crosshead speed of 5 mm/minute, until failure. Data was analyzed by ANOVA and Tukey’s range test. The titanium screws had higher fracture resistance, compared with PEEK and 30% carbon fiber-reinforced PEEK screws (p < 0.05). In contrast, no statistically significant difference was observed between the fracture resistance of the PEEK and the 30% carbon fiber-reinforced PEEK screws (p> 0.05). Finally, visual analysis of the fractions revealed that 100% of them occurred at the neck of the abutment screw, suggesting that this is the weakest point of this unit. PEEK abutment screws have lower fracture resistance, in comparison with titanium abutment screws.

https://doi.org/10.1590/1807-3107BOR-2014.vol28.0028 5163 downloads

13.

Smoking influences on the thickness of marginal gingival epithelium
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Villar, Cristina Cunha Lima, Antonio Fernando Martorelli de

Pesquisa Odontológica Brasileira

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mar 2003, Volume 17 N. 1 Pages 41 - 45

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Pacientes fumantes freqüentemente apresentam redução dos sinais clínicos inflamatórios da gengivite, associada, em grande parte, a vasoconstrição local e aumento da espessura epitelial. O objetivo deste trabalho foi avaliar a espessura do epitélio oral da gengiva marginal de pacientes fumantes e não fumantes, nos estados de saúde gengival e gengivite. Foram obtidos vinte fragmentos de tecido gengival de quatro grupos de pacientes. Grupo I: não fumantes com saúde gengival (n = 5). Grupo II: não fumantes com gengivite (n = 5). Grupo III: fumantes com saúde gengival (n = 5). Grupo IV: fumantes com gengivite (n = 5). As biópsias receberam processamento histológico de rotina, e os cortes semi-seriados com 5 mm de espessura foram corados com H. E. Com auxílio do sistema de imagens KS400 foram quantificadas a espessura epitelial maior e a espessura da base epitelial e determinados os valores dos perímetros epiteliais externo e interno. Os dados foram avaliados pelo ANOVA e pelo teste de Tukey, considerando significativo o valor de a = 0,05. Os resultados mostraram valores da espessura da base epitelial maior (p < 0,05) nos pacientes fumantes, independentemente do estado de saúde gengival.

Smoking patients show reduction of inflammatory clinical signs that might be associated with local vasoconstriction and an increased gingival epithelial thickness. The purpose of this work was to evaluate the thickness of the marginal gingival oral epithelium in smokers and non-smokers, with clinically healthy gingivae or with gingivitis. Twenty biopsies were obtained from four different groups. Group I: non-smokers with clinically healthy gingivae (n = 5). Group II: non-smokers with gingivitis (n = 5). Group III: smokers with clinically healthy gingivae (n = 5). Group IV: smokers with gingivitis (n = 5). These biopsies were histologically processed, serially sectioned at 5 mm, stained with H. E., and examined by image analysis software (KS400), which was used to perform the morphometric evaluation and the quantification of the major epithelial thickness, the epithelial base thickness and the external and internal epithelial perimeters. Differences between the four groups were analyzed using ANOVA test and Tukey's test. The criteria for statistical significance were accepted at the probability level p < 0.05. A greater epithelial thickness was observed in smokers independent of the gingival health situation.

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