Abstract This study assessed the color-matching ability and color recovery of unprepared teeth when using single-shade composites and a universal composite in large restorations. Buccal and palatine surface colors of molars were measured with a spectrophotometer (CIELAB) before preparing round cavities (6 mm in diameter, 2 mm in depth). The cavities were randomly filled with a single-shade composite (Omnichroma, Diamond One, or Vittra APS Unique) or a universal composite (Filtek Universal). Color measurements of the restored cavities were taken, and overall color differences (ΔEab and ΔE00) and differences in the whitening index for dentistry (ΔWID) from baseline were calculated. Additionally, visual assessments of a color match to the surrounding enamel were performed by forty evaluators (laypersons and undergraduate students of dentistry) in a viewing booth under illuminant D65, with rating scores from 0 (no color mismatch) to 4 (not acceptable). Data were analyzed using RM or one-way ANOVA (α = 0.05). Results showed that the restorations generally exhibited whiter colors (WID ranged from 27.9 to 41.3) than the unprepared teeth (WID ranged from 15.9 to 19.3). The composite Filtek Universal demonstrated the lowest color discrepancy (ΔWID = 8.6; ΔE00 = 10.8; and ΔE00 = 6.2), and no significant differences were observed among the evaluated single-shade composites. Furthermore, all composites showed similar and adequate color matches to the surrounding enamel. However, it is important to note that despite their ability to match the surrounding enamel reasonably, none of the composites evaluated in large restorations fully recovered the color observed in unprepared teeth. colormatching matching singleshade single shade CIELAB (CIELAB 6 ( diameter depth. depth . depth) Omnichroma, Omnichroma (Omnichroma One Unique Universal. Universal) taken ΔEab ΔE ΔWID calculated Additionally laypersons D65 D mismatch not acceptable. acceptable acceptable) oneway one way α 0.05. 005 0.05 05 0.05) WID 279 27 9 27. 41.3 413 41 3 159 15 15. 19.3. 193 19.3 19 19.3) 8.6 86 8 ΔE0 10.8 108 10 6.2, 62 6.2 , 6.2) Furthermore However reasonably D6 00 0.0 41. 1 19. 8. 10. 6. 0.

Resumo Este estudo avaliou a habilidade de combinação de cores e recuperação de cor de dentes não preparados ao utilizar resinas compostas de única tonalidade e uma resina composta universal em grandes restaurações. As cores das superfícies bucais e palatinas de molares foram medidas com um espectrofotômetro (CIELAB) antes de preparar cavidades esféricas (6 mm de diâmetro, 2 mm de profundidade). As cavidades foram preenchidas aleatoriamente com uma resina composta de única tonalidade (Omnichroma, Diamond One ou Vittra APS Unique) ou com uma resina composta universal (Filtek Universal). Foram realizadas medições das cores das cavidades restauradas e calculadas as diferenças de cor globais (ΔEab and ΔE00)) e as diferenças no índice de clareamento para odontologia (ΔWID) em relação à cor inicial. Além disso, foram realizadas avaliações visuais da correspondência de cor com o esmalte circundante por quarenta avaliadores (leigos e estudantes de odontologia) em uma cabine de visualização sob iluminante D65, com pontuações de 0 (nenhuma discrepância de cor) a 4 (não aceitável). Os dados foram analisados usando RM ou ANOVA unidirecional (α = 0,05). Os resultados mostraram que as restaurações geralmente apresentavam cores mais brancas (WID variou de 27,9 a 41,3) do que os dentes não preparados (WID variou de 15,9 a 19,3). A resina composta Filtek Universal demonstrou a menor discrepância de cor (ΔWID = 8,6; ΔE00 = 10,8; and ΔE00 = 6,2), e não foram observadas diferenças significativas entre as resinas compostas de única tonalidade avaliadas. Além disso, todas as resinas compostas apresentaram correspondência de cor similar e adequada com o esmalte circundante. No entanto, é importante observar que, apesar de sua capacidade de corresponder razoavelmente com o esmalte circundante, nenhuma das resinas compostas avaliadas em grandes restaurações recuperou completamente a cor observada nos dentes não preparados. CIELAB (CIELAB 6 ( diâmetro profundidade. profundidade . profundidade) Omnichroma, Omnichroma (Omnichroma Unique Universal. Universal) ΔEab ΔE ΔE00) ΔWID inicial disso leigos D65 D aceitável. aceitável aceitável) α 0,05. 005 0,05 05 0,05) WID 279 27 9 27, 41,3 413 41 3 159 15 15, 19,3. 193 19,3 19 19,3) 8,6 86 8 ΔE0 10,8 108 10 6,2, 62 6,2 , 6,2) entanto D6 00 0,0 41, 1 19, 8, 10, 6, 0,

Abstract Repositioning guides are commonly employed in clinical studies to ensure consistent tooth color measurements. Yet, their influence on measured color remains uncertain. Objective This study evaluated the impact of repositioning guides’ color and usage on tooth color measurement using a clinical spectrophotometer. Methodology In total, 18 volunteers participated in this study, in which the color of their upper left central incisor and upper left canine was measured with or without repositioning guides (control). The guides were made from pink, blue, or translucent silicone, as well as an acetate-based bleaching tray. Tooth color was measured in triplicates using a clinical spectrophotometer based on the CIELAB system. The standard deviations of these readings were used to estimate reproducibility, and color differences (ΔE00) between the measurements with guides and the control were calculated. Results Repositioning guides had a minimal effect on L* values and no effect on b* values. The use of pink silicone increased a* values, whereas blue or translucent silicone reduced them. Irrespective of the evaluated tooth, the lowest ΔE00 values were observed for the translucent silicone and bleaching tray. The usage of guides only affected data variability for the L* color coordinate. Conclusion Using repositioning guides can significantly impact the precision of tooth color measurement with a clinical spectrophotometer. Yet uncertain total 1 control. . (control) acetatebased acetate tray system reproducibility ΔE (ΔE00 calculated L b them ΔE0 coordinate (control (ΔE0 (ΔE

RESUMO Objetivo: Este estudo observacional descritivo teve como objetivo determinar dados clinicamente relevantes e aplicáveis da espessura do esmalte (EES), considerando as diferenças mésiodistais dos dentes anteriores e posteriores e suas relações. Material e Métodos: A amostra consistiu em radiografias periapicais padronizadas do lado direito de 34 indivíduos, 21 do sexo feminino e 13 do sexo masculino, com idade entre 13 e 24 anos (média = 16 anos), com todos os dentes permanentes íntegros e sem apinhamento. Quatro radiografias periapicais e quatro radiografias interproximais foram tiradas e digitalizadas. As medidas de EES (dos pontos de contato mesial e distal até a junção dentina-esmalte) foram realizadas após correção para adequar a ampliação da imagem radiográfica. Para as diferenças entre as médias pareadas, foi aplicado o teste t de Student com correlação de Pearson, para avaliar a correlação entre elas. Resultados: A EES mesial e distal aumenta dos dentes anteriores para os posteriores. A EES dos incisivos variou entre 0,6 e 0,84 mm. Caninos, pré-molares e molares apresentaram EES superior a 1,0 mm e a EES dos molares atingiu valores entre 1,26 e 1,44 mm. Conclusão: As EES distais são significativamente maiores que as mesiais e progressivamente mais espessas dos dentes anteriores para posteriores. A redução interproximal do esmalte (RIP) dos incisivos centrais inferiores e laterais superiores deve ser evitada, minimizada ou realizada em suas superfícies distais. Radiografias periapicais e avaliação da EES remanescente são necessárias nos casos de retratamento. A localização e o número de discrepâncias no tamanho dos dentes devem ser determinados e considerados no planejamento do tratamento, para que sejam adequadamente compensados durante o tratamento com RIP. Objetivo EES, , (EES) relações Métodos 3 indivíduos 2 1 masculino média anos, anos) apinhamento digitalizadas dentinaesmalte dentina dentina-esmalte radiográfica pareadas Pearson elas Resultados 06 0 6 0, 084 84 0,8 Caninos prémolares pré 10 1, 126 26 1,2 144 44 1,4 Conclusão RIP (RIP evitada retratamento (EES 08 8 12 14 4

ABSTRACT Objective: This descriptive observational study aimed to determine clinically relevant and applicable data of enamel thickness (ETH), considering the mesio-distal differences of anterior and posterior permanent teeth and their relationships. Material and Methods: The sample consisted of right-sided standardized radiographs of 34 individuals (21 females and 13 males), aged between 13 and 24 (average 16) years, with all permanent teeth intact and without crowding. Four periapical and four interproximal radiographs were obtained and digitized. ETH measurements (mesial to distal contact points at the dentin-enamel junction) were performed after correction for radiographic image magnification. The Students’ t-test was applied to the differences between paired means, with the Pearson correlation to evaluate the correlation between them. Results: The mesial and distal ETH increased from the anterior to the posterior teeth. Incisor ETH ranged between 0.60 and 0.84 mm. Canines, premolars, and molars were more than 1.0 mm thick, and molar enamel reached values between 1.26 and 1.44 mm. Conclusion: Distal ETH was significantly greater than the mesial ETH, and progressively thicker from the anterior to posterior teeth. Interproximal reduction (IPR) of the lower central and upper lateral incisors should be avoided, reduced, or performed on their distal surfaces. There is a positive and significant correlation between ETH and the mesial and distal surfaces of the teeth. Periapical radiographs and evaluation of the remaining ETH are necessary in cases of retreatment. The location and number of tooth size discrepancies should be considered in treatment planning and appropriately compensated with IPR. Objective , (ETH) mesiodistal mesio relationships Methods rightsided right sided 3 21 (2 1 males, males males) 2 average 16 years crowding digitized dentinenamel dentin junction magnification Students ttest t test means them Results 060 0 60 0.6 084 84 0.8 Canines premolars 10 1. thick 126 26 1.2 144 44 1.4 Conclusion IPR (IPR avoided reduced retreatment (ETH ( 06 6 0. 08 8 12 14 4

Abstract Cancer is a complex and multifactorial disease characterized by uncontrolled cell growth and is one of the main causes of death in the world. This work aimed to evaluate a small series of 10 different indole-thiosemicarbazone compounds as potential antitumor agents. This is a pioneering study. For this, the antioxidant and cytotoxic capacity against normal and tumor cells was evaluated. The results showed that the compounds were able to promote moderate to low antioxidant activity for the ABTS radical scavenging assay. ADMET in silico assays showed that the compounds exhibited good oral bioavailability. As for toxicity, they were able to promote low cytotoxicity against normal cells, in addition to not being hemolytic. The compounds showed promising in vitro antitumor activity against the T47D, MCF-7, Jurkat and DU-145 strains, not being able to inhibit the growth of the Hepg2 strain. Through this in vitro study, it can be concluded that the compounds are potential candidates for antitumor agents. world 1 indolethiosemicarbazone indole thiosemicarbazone agents study evaluated assay bioavailability toxicity hemolytic T47D TD T D MCF7, MCF7 MCF 7, 7 MCF-7 DU145 DU 145 DU-14 strains Hepg strain MCF- DU14 14 DU-1 DU1 DU-

Resumen El Mixed Martial Arts obtuvo popularidad al promover combates como espectáculo. La institucionalización y racionalización de las reglas generó consumo y beneficios. Este estudio analiza el entrenamiento, la mercantilización y la formación de atletas del MMA partiendo de la teoría de la Industria Cultural (IC). Utilizamos observación y entrevistas semiestructuradas con 6 luchadores y 3 preparadores físicos y los datos obtenidos fueron sometidos a análisis de contenido con la ayuda del software QSR NVivo. Surgieron tres categorías: Historial de ingreso a las MMA; Entrenamiento y funcionalidad de los cuerpos; MMA y mercantilización. Los cuerpos de las atletas son manipulados y programados, entrenados con precisión y hermosos para convertirse en consumibles.

Resumo O Mixed Martial Arts ganhou popularidade ao promover combates como espetáculo. A institucionalização e racionalização das regras gerou consumo e lucros. Este estudo analisa o treinamento, a mercantilização e a formação das atletas de MMA a partir da teoria da Indústria Cultural (IC). Utilizamos a observação e a entrevista semiestruturada com 6 lutadoras e 3 preparadores/as físicos/as, tendo os dados obtidos sido submetidos a análise de conteúdo com auxílio do software QSR NVivo. Três categorias emergiram: Trajetória de inserção no MMA; Treinamento e funcionalidade dos corpos; MMA e mercadorização. Os corpos das atletas são manipulados e programados, precisamente treinados e belos para tornarem-se consumíveis.

Abstract Mixed Martial Arts gained popularity by promoting show fighting. The institutionalization and rationalization of the rules generated consumption and profits. This study analyses the coaching, commodification and training of athletes within MMA from the perspective of the Cultural Industry (CI) theory. We used observation and semi-structured interviews with 6 fighters and 3 specialist sport conditioning trainers, and the resulting data were subjected to content analysis with the aid of QSR NVivo software. Three categories emerged: Trajectory of female fighters in MMA; Training and functionality of athletes' bodies; MMA and sports commodification. Athletes' bodies are managed and programmed, precisely trained and made beautiful to become consumable.

RESUMO O objetivo do estudo foi identificar as barreiras encontradas pelos profissionais de educação física no atendimento a pessoas com deficiência em meio à pandemia do Covid-19. A pesquisa foi descritiva transversal e de natureza exploratória. O instrumento utilizado para a realização deste estudo apoiou-se em um questionário de criação própria dos pesquisadores, sendo validado por meio do método face validty que constitui de três profissionais doutores da área da Educação Física que formularam parecer sobre o questionário. Os critérios de inclusão foram ser profissional de Educação Física, atuante com pessoas com deficiência por meio da prática esportiva. Já para critério de exclusão foram profissionais não graduados em educação física e sem registro profissional. A amostra do presente estudo foi constituída por 64 profissionais de Educação Física que oferecem aulas para pessoas com deficiência em todo território Brasileiro. Apresentaram uma significativa prevalência para variação de modelo de aulas, dificuldades no emprego da execução das atividades e o desinteresse dos alunos em realizar os exercícios de forma virtual. Conclui-se que as barreiras encontradas pelos profissionais de educação física que atuam diretamente com Pessoas com Deficiência foram as adaptações curriculares, metodológicas, as fragilidades do uso da ferramenta tecnológica e os fatores de ensino aprendizagem.

ABSTRACT The study aimed to identify the barriers encountered by physical education professionals in serving people with disabilities amid the Covid-19 pandemic. This study consisted of cross-sectional descriptive research of an exploratory nature. The instrument used to carry out this study was based on a questionnaire created by the researchers and validated through the face validity method, which consists of three professionals with a PhD in the field of physical education who formulated an opinion on the questionnaire. The inclusion criteria was to be a physical education professional working with people with disabilities through sports, while the exclusion criteria were professionals without a degree in physical education and professional registration. The present study sample consisted of 64 physical education professionals who offer classes for people with disabilities throughout Brazil. They presented a significant prevalence for the variation of the class model, difficulties in the use of the execution of the activities and the disinterest of the students in carrying out the exercises virtually. It is concluded that the barriers encountered by physical education professionals who work directly with People with Disabilities were the curricular and methodological adaptations, the weaknesses in using the technological tool and the teaching-learning factors.

RESUMO Este estudo buscou verificar os efeitos dos exercícios de dupla tarefa no equilíbrio, autonomia funcional e mobilidade dos idosos. Trata-se de um estudo longitudinal, quase experimental, descritivo e quantitativo, sendo selecionados nove idosos que se enquadravam nos critérios de inclusão e exclusão, após aplicação do Mini exame do estado mental. Participaram do estudo dois idosos do sexo masculino e sete do sexo feminino, durante oito semanas, com frequência de dois dias alternados. Foram avaliadas as seguintes variáveis: teste de equilíbrio de Tinetti, Grupo de Desenvolvimento Latino-Americano para a Maturidade (GDLAM), Timed Up & Go (TUG), TUG manual 1 e 2 e TUG cognitivo 1 a 6. O valor de p< 0,05 foi adotado para a significância estatística. Não houve redução significativa no Timed Up & Go, TUG manual 1 e 2 e TUG cognitivo 1 a 6. Ocorreu aumento significativo de 1,11 pontos pós intervenção (p= 0,007) do teste de equilíbrio de Tinetti e uma diminuição significativa (6,14 segundos) os exercícios de C10m (p= 0,001), LPS (5,67 segundos) (p= 0,004) e VTC (4,79 segundos) (p= 0,003). Nota-se também uma redução significativa (8,88 pontos) (p= 0,001) do escore IG. Conclui-se através dos resultados obtidos na presente pesquisa que houve melhora significativa no desempenho do equilíbrio e autonomia funcional dos idosos. Através desses achados infere-se que os idosos da pesquisa terão uma melhor autonomia e menor risco de quedas.

ABSTRACT This study sought to verify the effects of dual-task exercises on balance, functional autonomy and mobility of the elderly. This longitudinal, quasi-experimental, descriptive and quantitative study selected 9 elderly people who met the inclusion and exclusion criteria. After applying the Mini Mental State Examination, two males and seven females participated in the study for eight weeks, with a frequency of two alternate days. The following variables were evaluated: Tinetti balance test, Latin American Development Group for Maturity (GDLAM), Timed Up & Go (TUG), manual TUG 1 and 2 and cognitive TUG 1 to 6. The p< 0.05 was adopted for statistical significance. There was no significant reduction in Timed Up & Go, manual TUG 1 and 2 and cognitive TUG 1 to 6. There was a significant increase of 1.11 points post-intervention (p= 0.007) of the Tinetti balance test and a significant decrease (6.14 seconds) in the C10m exercises (p= 0.001), LPS (5.67 seconds) (p= 0.004) and VTC (4.79 seconds) (p= 0.003). There was also a significant reduction (8.88 points) (p= 0.001) in the IG score. It is concluded through the results obtained in this research that there was a significant improvement in the performance of balance and functional autonomy of the elderly. These findings show that the elderly in the present research will have better autonomy and a lower risk of falls.

Resumo Objetivou-se estimar a prevalência de hipertensão arterial (HA) e os fatores de risco associados em mulheres presas. Utilizou-se dados do Inquérito Nacional de Saúde na População Penitenciária Feminina e em Servidoras Prisionais, investigando-se características sociodemográficas, fatores das prisões, comportamentos e condições de saúde. As informações foram coletadas por meio de questionário autoaplicado, sendo a magnitude da associação estimada por odds ratio e intervalo de confiança de 95%. Das 1.327 participantes, 24,4% eram hipertensas, a maioria tinha 31 anos ou mais (54,6%), 51,5% autorreferiram etnia/cor parda. Após mutual ajustamento pelos fatores de risco associados na análise bivariada, observou-se relação direta e com gradiente entre idade e HA, em que idade igual/maior a 41 anos foi associada independentemente com uma chance sete vezes maior de ter HA, se comparado a quem tem menos de 25 anos. Aquelas que autorreferiram etnia/cor negra apresentaram colesterol alto e estavam obesas, também foram associadas de forma independente com maior prevalência de HA. O maior número de pessoas com que a presa divide cela esteve associado à maior prevalência de há, sem uma relação dose-resposta. Conclui-se que idade, etnia/cor, obesidade, inatividade física e estresse são fatores de risco para HA em mulheres presas.

Abstract The scope was to estimate the prevalence of arterial hypertension (AHT) and associated risk factors among female prisoners. Data from the National Health Survey of the Female Prison Population and Prison Guards were used, investigating sociodemographic variables, prison characteristics, health behaviors and conditions. Information was collected through a self-administered questionnaire, and the magnitude of the association was estimated by the odds ratio and 95% confidence interval. Of the 1,327 prisoner participants, 24.4% were hypertensive, the majority were 31 years of age or older (54.6%), and 51.5% self-reported mixed race. After adjustment for associated risk factors in the bivariate analysis, a direct relationship between age and AHT was observed, in which age equal to/over 41 years was independently associated with a 7-fold greater chance of having AHT, compared to those under 25 years of age. Those who self-reported mixed race, had high cholesterol, were obese and were also independently associated with a higher prevalence of AHT. The greater the number of people with whom the inmate shares a cell was associated with a higher prevalence of AHT, but without a dose-response relationship. The conclusion drawn is that age, race, obesity, physical inactivity and stress are risk factors for AHT in female prisoners.

Resumo Objetivou-se estimar a prevalência de hipertensão arterial (HA) e os fatores de risco associados em mulheres presas. Utilizou-se dados do Inquérito Nacional de Saúde na População Penitenciária Feminina e em Servidoras Prisionais, investigando-se características sociodemográficas, fatores das prisões, comportamentos e condições de saúde. As informações foram coletadas por meio de questionário autoaplicado, sendo a magnitude da associação estimada por odds ratio e intervalo de confiança de 95%. Das 1.327 participantes, 24,4% eram hipertensas, a maioria tinha 31 anos ou mais (54,6%), 51,5% autorreferiram etnia/cor parda. Após mutual ajustamento pelos fatores de risco associados na análise bivariada, observou-se relação direta e com gradiente entre idade e HA, em que idade igual/maior a 41 anos foi associada independentemente com uma chance sete vezes maior de ter HA, se comparado a quem tem menos de 25 anos. Aquelas que autorreferiram etnia/cor negra apresentaram colesterol alto e estavam obesas, também foram associadas de forma independente com maior prevalência de HA. O maior número de pessoas com que a presa divide cela esteve associado à maior prevalência de há, sem uma relação dose-resposta. Conclui-se que idade, etnia/cor, obesidade, inatividade física e estresse são fatores de risco para HA em mulheres presas.

Abstract The scope was to estimate the prevalence of arterial hypertension (AHT) and associated risk factors among female prisoners. Data from the National Health Survey of the Female Prison Population and Prison Guards were used, investigating sociodemographic variables, prison characteristics, health behaviors and conditions. Information was collected through a self-administered questionnaire, and the magnitude of the association was estimated by the odds ratio and 95% confidence interval. Of the 1,327 prisoner participants, 24.4% were hypertensive, the majority were 31 years of age or older (54.6%), and 51.5% self-reported mixed race. After adjustment for associated risk factors in the bivariate analysis, a direct relationship between age and AHT was observed, in which age equal to/over 41 years was independently associated with a 7-fold greater chance of having AHT, compared to those under 25 years of age. Those who self-reported mixed race, had high cholesterol, were obese and were also independently associated with a higher prevalence of AHT. The greater the number of people with whom the inmate shares a cell was associated with a higher prevalence of AHT, but without a dose-response relationship. The conclusion drawn is that age, race, obesity, physical inactivity and stress are risk factors for AHT in female prisoners.

ABSTRACT Background: We evaluated the association between polymorphisms in the tumor necrosis factor alpha (TNF-α) (-G308A) gene and upper gastrointestinal bleeding (UGIB) in schistosomiasis. Methods: This was a transverse study involving 294 Brazilian patients infected with Schistosoma mansoni. Results: The homozygous A/A genotype in TNF-α (-G308A) showed a risk association (prevalence ratio = 1.90, p = 0.008) with UGIB. There was no statistically significant difference in serum TNF-α levels between the clinical groups. Conclusions: The polymorphic TNF-α (-G308A) can be a risk factor for UGIB, in addition to being a potentially predictive factor for the severity of UGIB in schistosomiasis. Background TNFα TNF α (TNF-α G308A GA G A (-G308A (UGIB schistosomiasis Methods 29 mansoni Results AA prevalence 190 1 90 1.90 0.008 0008 0 008 groups Conclusions 2 19 9 1.9 0.00 000 00 1. 0.0 0.

ABSTRACT Introduction: Participants in cardiac rehabilitation programs have low adherence to their sessions, which makes extremely important to recognize the barriers that cause non-adherence, identifying whether the type of service and level of adherence influence these barriers. Methods: This is a cross-sectional observational study, in which 220 individuals (66.80±11.59 years) of both genders who are members of public and private exercise-based cardiac rehabilitation programs participated. The volunteers were divided according to the level of adherence, considering patients with low adherence (PLA) those with < 70% of attendance and high adherence (PHA) those with > 70%. Then, initial evaluation, Cardiac Rehabilitation Barriers Scale, analysis of socioeconomic level, Hospital Anxiety and Depression Scale, and Mini-Mental State Examination were applied. Results: Higher total barriers were found in PLA in the public service compared to PHA in the private service (P=0.023). In the subscale “perceived need”, PHA in the public service showed higher values than PLA and PHA in the private service (P≤0.001). The “access” barrier was higher for PHA in the public service when compared to PHA in the private service (P=0.024). PHA in the public service exhibited a higher barrier regarding questions about distance, transportation problems, cost, and time constraints. Conclusion: The public program presents higher barriers in the questions and categories compared to the private program, mainly the PHA. Furthermore, there are differences in the profile of the participants regarding socioeconomic and anxiety levels, treatment time, ethnicity, and city where they live. Introduction sessions nonadherence, nonadherence non non-adherence Methods crosssectional cross sectional study 22 66.80±11.59 66801159 66 80 11 59 (66.80±11.5 years exercisebased exercise based participated (PLA 70 (PHA Then evaluation Scale MiniMental Mini Mental applied Results P=0.023. P0023 P P=0.023 . 0 023 (P=0.023) perceived need, need , need” P≤0.001. P0001 P≤0.001 001 (P≤0.001) access “access P=0.024. P0024 P=0.024 024 (P=0.024) distance problems cost constraints Conclusion Furthermore levels ethnicity live 2 66.80±11.5 6680115 6 8 1 5 (66.80±11. 7 P002 P=0.02 02 (P=0.023 P000 P≤0.00 00 (P≤0.001 (P=0.024 66.80±11. 668011 (66.80±11 P00 P=0.0 (P=0.02 P≤0.0 (P≤0.00 66.80±11 66801 (66.80±1 P0 P=0. (P=0.0 P≤0. (P≤0.0 66.80±1 6680 (66.80± P=0 (P=0. P≤0 (P≤0. 66.80± 668 (66.80 P= (P=0 P≤ (P≤0 66.80 (66.8 (P= (P≤ 66.8 (66. (P 66. (66 (6 (

ABSTRACT Introduction: Participants in cardiac rehabilitation programs have low adherence to their sessions, which makes extremely important to recognize the barriers that cause non-adherence, identifying whether the type of service and level of adherence influence these barriers. Methods: This is a cross-sectional observational study, in which 220 individuals (66.80±11.59 years) of both genders who are members of public and private exercise-based cardiac rehabilitation programs participated. The volunteers were divided according to the level of adherence, considering patients with low adherence (PLA) those with < 70% of attendance and high adherence (PHA) those with > 70%. Then, initial evaluation, Cardiac Rehabilitation Barriers Scale, analysis of socioeconomic level, Hospital Anxiety and Depression Scale, and Mini-Mental State Examination were applied. Results: Higher total barriers were found in PLA in the public service compared to PHA in the private service (P=0.023). In the subscale “perceived need”, PHA in the public service showed higher values than PLA and PHA in the private service (P≤0.001). The “access” barrier was higher for PHA in the public service when compared to PHA in the private service (P=0.024). PHA in the public service exhibited a higher barrier regarding questions about distance, transportation problems, cost, and time constraints. Conclusion: The public program presents higher barriers in the questions and categories compared to the private program, mainly the PHA. Furthermore, there are differences in the profile of the participants regarding socioeconomic and anxiety levels, treatment time, ethnicity, and city where they live. Introduction sessions nonadherence, nonadherence non non-adherence Methods crosssectional cross sectional study 22 66.80±11.59 66801159 66 80 11 59 (66.80±11.5 years exercisebased exercise based participated (PLA 70 (PHA Then evaluation Scale MiniMental Mini Mental applied Results P=0.023. P0023 P P=0.023 . 0 023 (P=0.023) perceived need, need , need” P≤0.001. P0001 P≤0.001 001 (P≤0.001) access “access P=0.024. P0024 P=0.024 024 (P=0.024) distance problems cost constraints Conclusion Furthermore levels ethnicity live 2 66.80±11.5 6680115 6 8 1 5 (66.80±11. 7 P002 P=0.02 02 (P=0.023 P000 P≤0.00 00 (P≤0.001 (P=0.024 66.80±11. 668011 (66.80±11 P00 P=0.0 (P=0.02 P≤0.0 (P≤0.00 66.80±11 66801 (66.80±1 P0 P=0. (P=0.0 P≤0. (P≤0.0 66.80±1 6680 (66.80± P=0 (P=0. P≤0 (P≤0. 66.80± 668 (66.80 P= (P=0 P≤ (P≤0 66.80 (66.8 (P= (P≤ 66.8 (66. (P 66. (66 (6 (

Abstract This study evaluated the background and effect of surrounding colors on the color blending of a single-shade composite used in a thin layer. Disc-shaped specimens (1.0 mm thickness) were built with the Vittra APS Unique composite surrounded (dual specimens) or not surrounded (simple specimens) by a control composite (shade A1, A2, or A3). Simple specimens were also built with only control composites. The specimen color was measured against white and black backgrounds with a spectrophotometer (CIELAB system). The whiteness index for dentistry (WID) was calculated for simple specimens. Differences (ΔE00) in color and translucency parameters (ΔTP00) between the simple/dual specimens and the controls were calculated. The translucency adjustment potential (TAP) and color adjustment potential (CAP) were estimated based on the ratios between data from simple and dual specimens. The Vittra APS Unique composite showed higher WID values than the controls. No differences between ΔTP00_SIMPLE and ΔTP00_DUAL were observed for any of the shades. The composite shade did not affect TAP values. The lowest values of ΔE00_SIMPLE and ΔE00_DUAL were observed for shade A1 regardless of the background color. For the white background, ΔE00_SIMPLE values did not differ from those of ΔE00_DUAL for all shades. Only A1 showed ΔE00_DUAL values lower than ΔE00_SIMPLE when the black background was used. The highest modulus of CAP (negative values for the white background) was observed when shade A1 surrounded the Vittra APS Unique composite. The color blending ability of the single-shade resin composite used in a thin layer was affected by both the surrounding shade and background color. singleshade single Discshaped Disc shaped 1.0 10 1 0 (1. thickness A A2 A3. A3 . A3) composites CIELAB system. system system) (WID ΔE00 ΔE (ΔE00 ΔTP00 ΔTP (ΔTP00 simpledual (TAP (CAP ΔTP00SIMPLE ΔTPSIMPLE SIMPLE ΔTP00DUAL ΔTPDUAL DUAL shades ΔE00SIMPLE ΔESIMPLE ΔE00DUAL ΔEDUAL negative 1. (1 ΔE0 (ΔE0 ΔTP0 (ΔTP0 ( (ΔE (ΔTP

Abstract Introduction Febrile neutropenia (FN) is a serious complication of cancer chemotherapy. The present study aimed to identify risk factors for documented infection in pediatric patients with FN and cancer. Methods This prospective cohort study included patients under 18 years from 2016 to 2018. Infection was defined according to the Centers for Disease Control and Prevention criteria. Results A total of 172 febrile neutropenic episodes were evaluated. From univariate analysis, the risk factors were: female gender; monocyte count < 100 cell/mm³, platelets < 50,000, C-reactive protein (CRP) > 90 mg/dl and hemoglobin < 7mg/dl at the onset of an episode; two or more episodes of FN, and; fever onset; positive blood culture at the fever onset. Independent risk factors according to the multivariate analysis were: CRP at the onset of a febrile episode > 90mg/dl, fever onset and first blood culture with a positive result. The lowest probability of infection was related to first episode and to platelets > 50,000 at the onset of fever. Conclusion A CRP > 90 at the onset of a febrile episode, platelets < 50,000, second episode or more, first fever episode during hospitalization and positive first blood culture were found to be associated with a higher risk of infection and they could be useful for the establishment of risk scores for infection in neutropenic children. (FN chemotherapy 1 201 2018 criteria 17 evaluated gender 10 cellmm³ cellmm cell mm³ mm cell/mm³ 50000 50 000 Creactive C reactive (CRP 9 mgdl mg dl 7mgdl 7mg 90mgdl 90mg 90mg/dl result 50,00 children 20 cell/mm 5000 5 00 50,0 2 500 0 50,