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Farmacovigilância de vacinas contra COVID-19 no Brasil: ações realizadas, lições aprendidas e próximos passos
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Silva, Roberta Mendes Abreu Cabral, Cibelle Mendes Percio, Jadher da Nóbrega, Martha Elizabeth Brasil Kobayashi, Carla Dinamerica Martins, Adriano Ferreira Cardoso, Felipe Daniel Porto, Victor Bertollo Gomes Capovilla, Leon de Moraes, Mônica Brauner Andrade, Paulo Henrique Santos Fernandes, Eder Gatti

Revista Panamericana de Salud Pública

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2025, Volume 49 elocation e1

Abstract: Pt En Es | Text: Pt En Es | PDF: Pt | PDF: En | PDF: Es

RESUMO Objetivo: Documentar as ações de farmacovigilância das vacinas contra a covid-19 que foram desenvolvidas pelo Programa Nacional de Imunizações do Brasil. Métodos: Pesquisa documental informativa no período de 2020 a 2023. Foram utilizadas fontes documentais do Ministério da Saúde durante a vacinação contra a covid-19 para análise e interpretação das ações realizadas. A análise foi subdividida nas etapas de preparação e operacionalização. As publicações foram organizadas de acordo com o título, data da publicação, descrição e link de acesso. Resultados: Foram encontrados e avaliados 86 documentos publicados durante a preparação e operacionalização da vacinação. Na fase de preparação, foi constituída a Câmara Técnica de Assessoramento em Imunizações e publicadas notas técnicas específicas para as vacinas contra covid-19 e introdução do novo sistema de informação. Na etapa de operacionalização, foi instituído o Comitê Interinstitucional de Farmacovigilância de Vacinas e outros Imunobiológicos e implementados sistemas de vigilância sentinela hospitalar para Eventos Adversos de Interesse Especial e a vigilância da segurança da vacinação contra a covid-19 em gestantes. Conclusão: A farmacovigilância foi fortalecida no contexto da vacinação contra a covid-19 no Brasil. Frente às lacunas do conhecimento e infodemia sobre as novas vacinas, fez-se necessária a adoção de estratégias complementares ao sistema de vigilância passiva para o monitoramento da segurança da vacinação. Colaborações interinstitucionais, disponibilidade de recursos adicionais, flexibilidade e oportunidade dos sistemas de informação contribuíram para que as ações de preparação e resposta da farmacovigilância de vacinas contra a covid-19 fossem efetivadas de forma abrangente no Brasil.

ABSTRACT Objective: To document the actions taken by Brazil’s National Immunization Program for the pharmacovigilance of COVID-19 vaccines. Methods: Documentary research on the period 2020 to 2023. Documentary sources from the national Ministry of Health during COVID-19 vaccination were used to analyze and interpret the actions taken. The analysis was split into two stages: preparation and operationalization. The publications were organized according to title, date of publication, description, and URL. Results: A total of 86 documents published during the preparation and operationalization of vaccination were found and evaluated. In the preparation phase, a technical advisory board on immunization was set up and specific technical notes were published for COVID-19 vaccines and the introduction of a new information system. In the operationalization stage, the Interinstitutional Committee for Pharmacovigilance of Vaccines and other Immunobiologicals was created. Also, hospital sentinel surveillance systems were established for adverse events of special interest, and surveillance of COVID-19 vaccination safety in pregnant women was implemented. Conclusion: Pharmacovigilance was strengthened in the context of COVID-19 vaccination in Brazil. Given the gaps in knowledge about the new vaccines, as well as the infodemic surrounding them, it was necessary to adopt strategies to complement the passive surveillance system for monitoring vaccination safety. Inter-institutional collaboration, the availability of additional resources, and flexible and timely information systems all contributed to a comprehensively effective preparation and response in the pharmacovigilance of COVID-19 vaccines in Brazil.

RESUMEN Objetivo: Documentar las medidas de farmacovigilancia de las vacunas contra la COVID-19 adoptadas por el Programa Nacional de Inmunización de Brasil. Métodos: Investigación documental informativa durante el período 2020-2023. Se utilizaron fuentes documentales del Ministerio de Salud durante la vacunación contra la COVID-19 para analizar e interpretar las medidas adoptadas. El análisis se subdividió en las fases de preparación y ejecución. Las publicaciones se organizaron por título, fecha de publicación, descripción y enlace de acceso. Resultados: Se encontraron y evaluaron 86 documentos publicados durante las fases de preparación y ejecución. En la fase de preparación, se creó el Grupo Técnico Asesor sobre Inmunización y se publicaron notas técnicas específicas para las vacunas contra la COVID-19 y la introducción del nuevo sistema de información. En la fase de ejecución, se creó el Comité Interinstitucional de Farmacovigilancia de Vacunas y otros Productos Inmunobiológicos y se pusieron en marcha sistemas de vigilancia centinela hospitalaria para los eventos adversos de interés especial y de vigilancia de la seguridad de la vacunación contra la COVID-19 en las embarazadas. Conclusión En Brasil, se ha fortalecido la farmacovigilancia en el contexto de la vacunación contra la COVID-19. Dadas las lagunas en el conocimiento y la infodemia sobre las nuevas vacunas, fue necesario adoptar estrategias complementarias al sistema de vigilancia pasiva para el seguimiento de la seguridad de la vacunación. Las relaciones de colaboración interinstitucional, la disponibilidad de recursos adicionales y los sistemas de información flexibles y oportunos han contribuido a la ejecución integral de las medidas de preparación y respuesta en materia de farmacovigilancia de las vacunas contra la COVID-19 en Brasil.

https://doi.org/10.26633/rpsp.2025.1

Genotype × environment interaction in yellow melon hybrids in different locations and growing seasons
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Cavalcante Neto, José Galdino

; Nunes, Elaíne Welk Lopes Pereira

; Silva, Edicleide Macedo da

; Martins, Adriano Ferreira

; Diógenes, Luiz José Pitombeira

; Melo, Stefeson Bezerra de

; Costa Filho, José Hamilton

; Nunes, Glauber Henrique de Sousa

Bragantia

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2025, Volume 84 elocation e20240047

Abstract: En | Text: En | PDF: En

ABSTRACT Melon (Cucumis melo L.) is cultivated worldwide, with prominence in the Northeast region of Brazil, due to its favorable soil and climate conditions. However, over the years, the genotype × environment (GxE) interaction phenomenon has been occurred, which can complicate the selection process depending on its extent (whether it is a simple or complex interaction). In this context, melon breeding programs aim to identify adaptable and stable genotypes, capable of reaching their maximum potential. Therefore, the objectives of this study were to investigate GxE interactions and identify cultivars with greater adaptability and phenotypic stability using various methods for comparison. Thirteen melon hybrids were assessed in four municipalities in the state of Rio Grande do Norte, across two planting dates, totaling eight distinct environments. The experiments were conducted in randomized complete blocks with three replications. The traits evaluated included the number of fruits per plant and total soluble solids. Several adaptability and stability methods were employed and compared including Wricke, Eberhart and Russell, Lin and Binns, Annicchiarico, GGE Biplot, and Resende (harmonic mean of relative performance of genotypic values). Significant GxE interaction for the number of fruits per plant was found to be simple, whereas for soluble solids, it was crossed. The methods of Linn and Binns, Annicchiarico, and Resende showed strong correlations among them and were all correlated with the trait mean. The HA-08 hybrid emerged as the most promising, exhibiting high number of fruits per plant, high soluble solids content, and exceptional adaptability and stability.

https://doi.org/10.1590/1678-4499.20240047

Number of replicates in trials for evaluating melon hybrids
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Araújo Junior, Bernardo Bezerra de

; Martins, Adriano Ferreira

; Nunes, Elaíne Welk Lopes Pereira

; Melo, Stefeson Bezerra de

; Nunes, Glauber Henrique de Sousa

Revista Ciência Agronômica

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2024, Volume 55 elocation e20217888

Abstract: En | Text: En | PDF: En

ABSTRACT During experiment planning, determining the number of replicates for tested treatments is important because it directly affects the accuracy of the obtained results. This study was conducted to determine the number of measurements (repetitions) necessary to evaluate the yield traits and soluble solids in Cantaloupe and Gália melon hybrid trials. The study comprised twenty-one experiments, nine for evaluating eight Cantaloupe melon hybrids, and twelve for evaluating nine Galia melon hybrids, conducted in a randomized complete block design with three replicates each. Analysis of variance was performed, and repeatability and genotypic determination coefficients were estimated for each experiment. The use of three repetitions allowed identification of superior genotypes with 83.6 and 80.7% predictions of the real values for the yield and soluble solids, respectively, for Cantaloupe melons. Evaluating the trials with Galia melon using three repetitions allowed prediction of the true value of the genotypes with 86.1 and 98.6% accuracy for fruit yield and soluble solids, respectively. Therefore, the use of three replicates was determined to be sufficient for detecting superior genotypes both for fruit yield and soluble solid content, with more than 80% certainty for their true values.

https://doi.org/10.5935/1806-6690.20240007

Use of insect repellent as personal protection among women of childbearing age in an arbovirus endemic area in Northeastern Brazil
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Dias, Livia Karla Sales

; Sanhueza-Sanzana, Carlos

; Pinheiro Júnior, Francisco Marto Leal

; Martins, Adriano Ferreira

; Correia, Francisco Gustavo Silveira

; de Aguiar, Italo Wesley Oliveira

; Ferreira, Nayane Cavalcante

; Stolow, Jeni

; Rutherford, George

; Teixeira, Maria Gloria

; Pires Neto, Roberto da Justa

; de Almeida, Rosa Livia Freitas

; Coelho, Ivo Castelo Branco

; Frota, Cristiane Cunha

; Kendall, Carl

; Kerr, Ligia Regina Franco Sansigolo

Revista Brasileira de Epidemiologia

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2024, Volume 27 elocation e240025

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Objetivo: Analisar os fatores associados ao uso de repelente individual por mulheres em idade fértil residentes em área endêmicas para arboviroses em Fortaleza, Brasil. Métodos: Coorte realizada entre 2018 e 2019, com mulheres entre 15 e 39 anos, moradoras em Fortaleza, Ceará, Brasil. Participaram 1.173 mulheres, usuárias de quatro unidades primárias de saúde do município. O desfecho foi categorizado em: uso continuado, uso descontinuado e não uso de repelente. Realizada análise de regressão logística multinominal norteada por modelo hierárquico, com apresentação dos respectivos odds ratio (OR) e intervalos de confiança de 95% (IC95%). As variáveis independentes incluem: dados socioeconômicos e demográficos, características ambientais e sanitárias, conhecimento sobre o repelente e aspectos comportamentais e relacionados à gravidez. Resultados: Somente 28% das participantes referiram o uso de repelente durante as duas ondas da coorte. Mulheres com escolaridade superior (OR=2,55; IC95% 1,44–4,51); com emprego (OR=1,51; IC95% 1,12–2,03); que receberam orientações por profissionais da saúde (OR=1,74; IC95% 1,28–2,36) e pela mídia (OR=1,43; IC95% 1,01–2,02); que intensificaram os cuidados contra o mosquito na epidemia (OR=3,64; IC95% 2,29–5,78); estavam grávidas entre 2016 e 2019 (OR=2,80; IC95% 1,83–4,30) tiveram as chances aumentadas para uso continuado de repelente. Conclusões: O uso de repelente entre mulheres em idade fértil mostrou-se associado a um maior nível de escolaridade, ao emprego, às orientações sobre repelente fornecidas por profissionais de saúde e pela mídia, às mudanças comportamentais de cuidado contra o mosquito durante a epidemia da Zika e à gravidez quando ocorrida a partir do início do período epidêmico.

ABSTRACT Objective: To analyze the factors associated with the individual use of insect repellent by women of childbearing age living in area endemic for arboviruses in Fortaleza, Brazil. Methods: This is a cohort study carried out between 2018 and 2019 with women aged between 15 and 39 years in Fortaleza, state of Ceará, Brazil. A total of 1,173 women users of one of the four selected primary health care units participated in the study. The outcome was divided into: continued use, discontinued use, and nonuse of insect repellent. Crude and adjusted multinominal logistic regression analysis was carried out guided by a hierarchical model, with presentation of the respective odds ratio (OR) and 95% confidence intervals (95%CI). The independent variables include: socioeconomic and demographic data, environmental and sanitary characteristics, knowledge of the insect repellent, and behavioral and pregnancy-related aspects. Results: Only 28% of the participants reported using insect repellent during the two waves of the cohort. Women with higher education (OR=2.55; 95%CI 1.44–4.51); who are employed (OR=1.51; 95%CI 1.12–2.03); who received guidance from healthcare professionals (OR=1.74; 95%CI 1.28–2.36) and the media (OR=1.43; 95%CI 1.01–2.02); who intensified precautions against mosquitoes during the epidemic (OR=3.64; 95%CI 2.29–5.78); and who were pregnant between 2016 and 2019 (OR=2.80; 95%CI 1.83–4.30) had increased odds for continued use of insect repellent. Conclusion: The use of insect repellent among women of childbearing age was associated with a higher level of education, employment, guidance on insect repellent provided by healthcare professionals and the media, behavioral changes to protect against mosquitoes during the Zika virus epidemic, and pregnancy when occurring as of the beginning of the epidemic period.

https://doi.org/10.1590/1980-549720240025

Estudo descritivo dos eventos supostamente atribuíveis à vacinação contra a mpox no Brasil em 2023
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Silva, Roberta Mendes Abreu

; Kobayashi, Carla Dinamerica

; Martins, Adriano Ferreira

; Araújo, Ana Catarina de Melo

; Andrade, Paulo Henrique Santos

; Nóbrega, Martha Elizabeth Brasil da

; Cabral, Cibelle Mendes

; Moraes, Monica Brauner de

; Cardoso, Felipe Daniel

; Victer, Thayssa Neiva da Fonseca

; Krummenauer, Amanda

; Soares, Rodrigo Otávio Pereira Sayago

; Fernandes, Eder Gatti

; Percio, Jadher

Cadernos de Saúde Pública

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2024, Volume 40 N. 10 elocation e00006624

Abstract: Pt Es En | Text: Pt Es En | PDF: Pt | PDF: Es | PDF: En

Resumo: O objetivo deste estudo é descrever as ações de vigilância e segurança da vacina contra a mpox (Jynneos) no Brasil, de 2022 a 2023. Realizou-se estudo descritivo dos casos de mpox e dos eventos supostamente atribuíveis à vacinação e/ou imunização para vacina Jynneos, registrados nos sistemas de informação. Foram calculadas frequências absolutas e relativas e coeficientes de notificação de eventos supostamente atribuíveis à vacinação e/ou imunização por mil doses administradas. Foram registrados 9.596 casos de mpox e distribuídas 49 mil doses de vacina; dessas, 14.395 (31%) doses foram administradas e 65 eventos supostamente atribuíveis à vacinação e/ou imunização (4,5 por mil doses administradas) foram notificados. Todos os eventos supostamente atribuíveis à vacinação e/ou imunização foram não graves e 22 (33,8%) casos apresentaram reações relacionadas ao produto. Os resultados estão dentro da frequência esperada. No entanto, o número de doses administradas pode não ter sido suficiente para detectar eventos raros ou inusitados. Portanto, a vigilância contínua é necessária para garantir a efetividade e a segurança da vacinação, especialmente entre os grupos de maior risco.

Resumen: El objetivo fue describir las acciones de vigilancia y seguridad de la vacuna contra mpox (Jynneos) en Brasil, del 2022 al 2023. Se realizó un estudio descriptivo de los casos de mpox y de los eventos supuestamente atribuibles a la vacunación o inmunización para la vacuna Jynneos, registrados en los sistemas de información. Se calcularon frecuencias absolutas y relativas y coeficientes de notificación de eventos supuestamente atribuibles a la vacunación o inmunización por 1.000 dosis administradas. Se registraron 9.596 casos de mpox y se distribuyeron 49.000 dosis de vacuna, de estas se administraron 14.395 (31%) dosis y se reportaron 65 eventos supuestamente atribuibles a la vacunación o inmunización (4,5 por 1.000 dosis administradas). Todos los eventos supuestamente atribuibles a la vacunación o inmunización no fueron graves y 22 (33,8%) casos tuvieron reacciones relacionadas con el producto. Los resultados son acordes a la frecuencia esperada. Sin embargo, puede que el número de dosis administradas no haya sido suficiente para detectar eventos raros o inusuales. Por lo tanto, es necesaria una vigilancia continua para garantizar la eficacia y la seguridad de la vacunación, especialmente entre los grupos con mayor riesgo de contraer la enfermedad.

Abstract: This study describes the surveillance and safety actions of the mpox (Jynneos) vaccine in Brazil, from 2022 to 2023. A descriptive study of mpox cases and events supposedly attributable to vaccination and/or immunization for Jynneos vaccine, recorded in the information systems, was conducted. Absolute and relative frequencies and reporting coefficients of events supposedly attributable to vaccination and/or immunization per 1,000 administered doses were calculated. A total of 9,596 cases of mpox were registered and 49,000 doses of vaccine were distributed, of which 14,395 (31%) were administered and 65 events supposedly attributable to vaccination and/or immunization (4.5 per 1,000 administered doses) were notified. All events supposedly attributable to vaccination and/or immunization were non-serious, and 22 (33.8%) cases had product-related reactions. Results are within the expected frequency; however, the number of administered doses may not have been sufficient to detect rare or unusual events. Continued surveillance is necessary to ensure vaccination effectiveness and safety, especially among groups at higher risk for the disease.

https://doi.org/10.1590/0102-311xpt006624

Estudo descritivo dos eventos supostamente atribuíveis à vacinação contra a mpox no Brasil em 2023
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Silva, Roberta Mendes Abreu

; Kobayashi, Carla Dinamerica

; Martins, Adriano Ferreira

; Araújo, Ana Catarina de Melo

; Andrade, Paulo Henrique Santos

; Nóbrega, Martha Elizabeth Brasil da

; Cabral, Cibelle Mendes

; Moraes, Monica Brauner de

; Cardoso, Felipe Daniel

; Victer, Thayssa Neiva da Fonseca

; Krummenauer, Amanda

; Soares, Rodrigo Otávio Pereira Sayago

; Fernandes, Eder Gatti

; Percio, Jadher

Cadernos de Saúde Pública

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2024, Volume 40 N. 10 elocation e00006624

Abstract: En Pt Es | Text: En Pt Es | PDF: En | PDF: Pt | PDF: Es

https://doi.org/10.1590/0102-311xpt006624

Number of replicates required to accurately evaluate the productivity and soluble solids in melon hybrids of the Inodorus group
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Araújo Junior, Bernardo Bezerra de

; Melo, Stefeson Bezerra de Martins, Adriano Ferreira Nunes, Elaíne Welk Lopes Pereira Nunes, Glauber Henrique de Sousa

Acta Scientiarum. Agronomy

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2024, Volume 46 elocation e62841

Abstract: En | Text: En | PDF: En

ABSTRACT. Determining the number of replicates required to produce statistically testable results based on previously conducted tests is important to minimize labor costs via the use of existing information. The objective of this work was to determine the number of repetitions necessary to evaluate the characters of productivity and soluble solids in hybrids of two types of Inodorus melons. The study consisted of 20 experiments: 12 evaluated 10 hybrids of honeydew melons and 8 evaluated 13 hybrids of yellow melons. The experimental design consisted of randomized blocks with three replicates. Analysis of variance was performed to estimate the repeatability and genotypic determination coefficients. Variability in accurately predicting the genotype was observed for different number of repetitions between the evaluated characters and melon types. In the yellow melon, experiments with three repetitions allowed the accurate identification of superior genotypes with 81.1 and 61.9% certainty for productivity and soluble solids, respectively. In the honeydew melon, 62.4 and 71.2% accuracy was obtained for productivity and soluble solids, respectively.

https://doi.org/10.4025/actasciagron.v46i1.62841

Use of insect repellent as personal protection among women of childbearing age in an arbovirus endemic area in Northeastern Brazil
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Dias, Livia Karla Sales

; Sanhueza-Sanzana, Carlos

; Pinheiro Júnior, Francisco Marto Leal

; Martins, Adriano Ferreira

; Correia, Francisco Gustavo Silveira

; de Aguiar, Italo Wesley Oliveira

; Ferreira, Nayane Cavalcante

; Stolow, Jeni

; Rutherford, George

; Teixeira, Maria Gloria

; Pires Neto, Roberto da Justa

; de Almeida, Rosa Livia Freitas

; Coelho, Ivo Castelo Branco

; Frota, Cristiane Cunha

; Kendall, Carl

; Kerr, Ligia Regina Franco Sansigolo

Revista Brasileira de Epidemiologia

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2024, Volume 27 elocation e240025

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

https://doi.org/10.1590/1980-549720240025

SOURCES AND INHERITANCE OF LEAFMINER RESISTANCE IN YELLOW MELON ACCESSIONS
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FERREIRA, ROBERTA ROCHA

; MARTINS, ADRIANO FERREIRA

; LOUREIRO, FRANCISCO LEANDRO COSTA

; ARAUJO, ELTON LUCIO DE

; NUNES, GLAUBER HENRIQUE DE SOUSA

Revista Caatinga

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oct 2022, Volume 35 N. 4 Pages 747 - 754

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO O uso de cultivares resistentes é um método eficiente e recomendável para manejo da mosca minadora, principal problema fitossanitário na cultura do meloeiro. Nesse contexto, os objetivos deste trabalho foram identificar fontes de resistência à mosca minadora em acessos de melão amarelo e determinar sua herança genética. Para tanto, foram realizados dois experimentos em campo nos municípios de Baraúna - RN e Icapuí - CE para identificar fontes de resistência. O delineamento adotado foi em blocos completos casualizados com 22 tratamentos e quatro repetições. Na avaliação foi quantificado o número de minas por folha. A heterogeneidade dos materiais estudados possibilitou identificar os acessos AM-RT e AM-TM como fontes de resistência, considerando que apresentaram número de minas igual a zero nos dois ambientes de avaliação. O acesso AM-RT foi selecionado e utilizado para obter a população S1 (autofecundação), população derivada de S1:2 e o cruzamento entre AM-RT e ‘Goldex’, que foram avaliadas em um terceiro ensaio de laboratório visando determinar o controle genético da resistência em AM-RT. Portanto, por meio do padrão de segregação das populações S1, S1:2 e do cruzamento (AM-RT’ and ‘Goldex’) avaliados, estimando-se os valores de qui quadrado (χ2), que foram de 1,33, 3,14 e 0,36, respectivamente, foi determinado que a herança da resistência é controlada por apenas um gene com dominância completa. Então, nesse estudo foram identificadas duas fontes de resistência à mosca minadora e um gene com dominância completa condiciona à resistência no acesso AM-RT.

ABSTRACT The use of resistant cultivars is an efficient and recommended method for the management of leafminers, which are the main phytosanitary problem in melons. The objectives of this study were to identify the sources of resistance to the leafminer in yellow melon accessions and to determine the resistance inheritance in acession AM-RT. Two field experiments were conducted in the municipalities of Baraúna, RN and Icapuí, CE, Brazil, to identify the sources of resistance. The design adopted was completely randomized blocks with 22 treatments and four replications. In this evaluation, the number of mines per leaf was quantified. The heterogeneity of the studied materials allowed for the identification of the accessions AM-RT and AM-TM as sources of resistance, considering that they revealed zero mines in the two evaluation environments. The accession AM-RT was selected and used to obtain the S1 population (by self-fertilization), S1:2 population derived from S1, and crossing between AM-RT and ‘Goldex’, which were evaluated in a third laboratory trial to determine the genetic control of resistance in that material. By the segregation pattern of the populations S1, S1:2, and the crossing (AM-RT and ‘Goldex’) and the estimation of the chi-squared (χ2) values, which were 1.33, 3.14, and 0.36, respectively, it was determined that the inheritance of resistance was controlled by only one gene with complete dominance. Therefore, in this study, two sources of resistance to the leafminer were identified, and resistance was conditioned by a gene with complete dominance in the accession ‘AM-RT’.

https://doi.org/10.1590/1983-21252022v35n401rc

10.

Stability, adaptability and shelf life of Cantaloupe melon hybrids
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Oliveira, Lenilton Alex de Araújo

; Cardoso, Eudes de Almeida

; Ricarte, Anânkia de Oliveira

; Martins, Adriano Ferreira

; Costa, José Maria da

; Nunes, Glauber Henrique de Sousa

Revista Brasileira de Fruticultura

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2019, Volume 41 N. 5 elocation e-418

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo A adoção de híbridos de melão pelo setor produtivo requer uma prévia avaliação quanto à produtividade, qualidade e vida útil pós-colheita de seus frutos. Devido as diferentes condições ambientais em que os híbridos são avaliados, espera-se que ocorra acentuada interação genótipos x ambientes e que a mesma tenha um importante papel na manifestação fenotípica. Diante disso, o presente trabalho teve como objetivo avaliar híbridos de melão no Estado do Rio Grande do Norte. Estimou-se a adaptabilidade e estabilidade dos valores genotípicos preditos pelo método MHPRVG (Média Harmônica da Performance Relativa dos Valores Genéticos) para os caracteres: produtividade e teor de sólidos solúveis (SS) no período de 2010 a 2015. Em 2017, avaliou-se os híbridos mais promissores em condições de cultivo comercial para produtividade, qualidade e vida útil pós-colheita. Verificou-se interação genótipos x ambientes para produtividade e SS com predomínio da parte complexa da interação. Os híbridos HC-02 e HC-11 são promissores para cultivo nas condições de semiárido do Agropolo Mossoró-Assu por possuir elevadas estabilidade, adpatabiliadade, produtividade e qualidade dos frutos. Os híbridos HC-02, HC-11 e ‘Hy Mark’ possuem vida útil pós-colheita que permitem sua comercialização no mercado externo.

Abstract The adoption of melon hybrids by the productive sector necessitates a prior evaluation of the productivity, quality and shelf life of their fruits. Due to the different environmental conditions under which the hybrids are evaluated, an accentuated genotype-environmental interaction is expected to become apparent and likewise play important role in manifestation of phenotypic traits. The objective of the present work was to evaluate melon hybrids in the state of Rio Grande do Norte. The adaptability and stability of the genetic values were estimated by the HMRPGV method (Harmonic Mean of the Relative Performance of Genetic Values) for the following traits: yield, and soluble solids (SS) content in the period between 2010 to 2015. In 2017, the more promising melon hybrids from previous trials were evaluated under commercial conditions to determine the fruit’s yield, quality and shelf life. The predominance of the complex part of the genotype-environmental interaction was verified for both yield and SS content. Hybrids HC-02 and HC-11 show promising traits when grown under the conditions of the Mossoró-Assu Agricultural Complex owing their high stability, adaptability, yield, and fruit quality. Hybrids HC-02, HC-11, and ‘Hy Mark’ are suitable as international exports due to their long shelf life.

https://doi.org/10.1590/0100-29452019418 884 downloads

11.

Projeto Mais Médicos para o Brasil: uma análise da Supervisão Acadêmica
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Almeida, Erika Rodrigues de Martins, Adriano Ferreira Macedo, Harineide Madeira Penha, Rodrigo Chávez

Interface - Comunicação, Saúde, Educação

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2017, Volume 21 Suppl. 1 Pages 1291 - 1300

Abstract: Pt En Es | Text: Pt En Es | PDF: Pt | PDF: En | PDF: Es

A carência de médicos no Brasil tem sido minimizada por meio do Programa Mais Médicos. Durante a permanência no programa, os médicos participam de processos de aperfeiçoamento profissional, como a Supervisão Acadêmica, por meio da qual é concedido apoio pedagógico para o fortalecimento de habilidades e competências necessárias ao trabalho na Atenção Básica. Em 2015, foram realizadas visitas in loco e atividades longitudinais de supervisão, além de encontros locorregionais, nos quais foram abordadas temáticas relacionadas às doenças crônicas não transmissíveis, às doenças tropicais negligenciadas, ao panorama do programa, à Saúde Mental e ao processo de trabalho na Atenção Básica. O elenco desses conteúdos converge com o perfil epidemiológico prevalente na população, bem como com a dinâmica de trabalho na Atenção Básica. Assim, a Supervisão Acadêmica tem se mostrado uma ferramenta potente para a qualificação do programa e da Atenção Básica.

The shortage of physicians in Brazil has been alleviated by the More Doctors Program. As part of the program, physicians participate in professional enhancement processes, such as academic supervision, through which pedagogical support is given to strengthen the necessary skills and competencies for working in Primary Care. In 2015, onsite visits and longitudinal supervisory activities took place, in addition to regional meetings, which addressed topics related to noncommunicable chronic diseases, neglected tropical diseases, an overview of the program, Mental Health, and Primary Care work process. This list of themes is consistent with the prevalent epidemiological profile of the population, as well as work dynamics in Primary Care. In short, Academic Supervision has proven to be a powerful tool for the program qualification and Primary Care.

La carencia de médicos en Brasil ha sido minimizada por medio del Programa Más Médicos. Durante la permanencia en el Programa, los médicos participan de procesos de perfeccionamiento profesional, como la supervisión académica por medio de la cual se proporciona apoyo pedagógico para el fortalecimiento de habilidades y competencias necesarias para el trabajo en la Atención Básica. En 2015, se realizaron visitas in situ y actividades longitudinales de supervisión, además de encuentros regionales in situ, en donde se abordaron temáticas relacionadas a las enfermedades crónicas no transmisibles, a las enfermedades tropicales negligenciadas, al panorama del Programa, a la salud mental y al proceso de trabajo en la Atención Básica. El conjunto de estos contenidos converge con el perfil epidemiológico prevalente en la población, así como con la dinámica de trabajo en la Atención Básica. Por lo tanto, la supervisión se ha mostrado una herramienta potente para la calificación del Programa y de la Atención Básica.

https://doi.org/10.1590/1807-57622016.0558 1987 downloads

12.

Projeto Mais Médicos para o Brasil: uma análise da Supervisão Acadêmica
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Almeida, Erika Rodrigues de Martins, Adriano Ferreira Macedo, Harineide Madeira Penha, Rodrigo Chávez

Interface - Comunicação, Saúde, Educação

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2017, Volume 21 Suppl. 1 Pages 1291 - 1300

Abstract: Pt Es En | Text: Pt Es En | PDF: Pt | PDF: Es | PDF: En

https://doi.org/10.1590/1807-57622016.0558

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