RESUMO Permeados por uma conjuntura que contempla relações humanas, sistemas de inteligência artificial e plataformas sociodigitais, os diversos modos de produção, compartilhamento e acesso às informações na contemporaneidade são marcados por uma ambiência de poder e política que, enquanto recurso estratégico, sustenta contextos socioculturais e modos de governança mediados pela desinformação. Diante disso, foi concebida essa pesquisa teórica e descritiva, com o objetivo de apresentar os principais elementos que, a partir da interface teórica que conecta conceitos de desinformação e regime de informação, compõem o que seria um regime de desinformação. Do ponto de vista epistemológico esse estudo oferece um novo olhar para este conceito apresentado com evidência, sobretudo, na Ciência da Informação: o regime de informação, na tentativa de adequá-lo a um ambiente social no qual a desinformação opera na transformação de estruturas e de noções estabelecidas ao longo do tempo. humanas sociodigitais produção estratégico disso descritiva informação evidência sobretudo Informação adequálo adequá lo tempo

ABSTRACT Permeated by a conjuncture that includes human relations, artificial intelligence systems and socio-digital platforms, the various ways of producing, sharing and accessing information in contemporary times are marked by an ambience of power and politics which, as a strategic resource, sustains socio-cultural contexts and modes of governance mediated by disinformation. In view of this, this theoretical and descriptive study was designed with the aim of presenting the main elements that, based on the theoretical interface that connects the concepts of disinformation and the information regime, make up what would be a disinformation regime. From an epistemological point of view, this study offers a new look at this concept that has been presented with evidence, especially in Information Science: the information regime, in an attempt to adapt it to a social environment in which disinformation operates in the transformation of structures and notions established over time. relations sociodigital socio digital platforms producing resource sociocultural cultural regime evidence Science time

Abstract Since bull fertility prediction remains challenging, the identification of potential fertility markers is important considering the economic benefits to the livestock industry. The main goal of this study was to determine the Na/K-ATPase activity and expression in thawed sperm of high (HF)- and low-fertility (LF) Angus bulls. Samples from three different batches/bulls with HF (n = 4) and LF (n = 4) were used. The Na/K-ATPase activity was determined after thawing, whereas sperm kinematics, membrane integrity, and expression of Na/K-ATPase on sperm surface were evaluated immediately post-thaw and after 120 minutes of incubation. Within the same incubation time, there was no difference on sperm membrane integrity, kinematics, and the expression of Na/K-ATPase on the sperm surface between HF and LF bulls. Kinematic parameters of LIN and VCL were not influenced by incubation time in samples from HF and LF, respectively. A tendency (P = 0.06) of higher Na/K-ATPase enzymatic activity for sperm of HF bulls compared to LF bulls was observed (0.49 ± 0.07 and 0.32 ± 0.06, respectively). In conclusion, Na/K-ATPase activity and expression in thawed sperm from Angus bulls are not related to the fertility index after fixed-time artificial insemination. However, sperm kinematics related to hyperactivation might indicate higher sperm cryotolerance for HF bulls. challenging industry Na/KATPase NaKATPase Na/K ATPase Na K (HF) lowfertility low (LF batchesbulls batches n 4 used thawing integrity postthaw post thaw 12 respectively P 0.06 006 0 06 0.49 049 49 (0.4 007 07 0.0 032 32 0.3 . respectively) conclusion fixedtime fixed insemination However KATPase NaK (HF 1 00 0.4 04 (0. 0. 03 3 (0 (

Abstract Interprofessionality was the central theme of the ninth call for proposals of the Education by Working for Health Program. The objective of this study was to describe the readiness of students who participated in the program for interprofessional learning. The research, of a quantitative approach and descriptive-exploratory perspective, collected data by applying the readiness for interprofessional learning scale (RIPLS), adapted for Brazilian Portuguese. The results indicate an important readiness for teamwork and collaboration. Relevant percentages were also found regarding professional identity, indicating good readiness for interprofessional learning, although aspects related to competition appeared in lower percentages of agreement regarding shared learning and interdependence of professional practices. For user-centered care, results were also found indicating good readiness among participants; however, aspects related to the collaboration of the user in the production of health services still express the tendency of a professional-centered logic. In conclusion, there is a positive readiness for interprofessional education, which needs to be increasingly stimulated in policies and strategies of curricular reforms. Program research descriptiveexploratory descriptive exploratory perspective RIPLS, RIPLS , (RIPLS) Portuguese identity practices usercentered centered care participants however professionalcentered logic conclusion education reforms (RIPLS

Resumo A interprofissionalidade foi tema central do nono edital do Programa de Educação pelo Trabalho para a Saúde. O objetivo deste estudo foi descrever a disponibilidade dos estudantes que participaram do programa para a aprendizagem interprofissional. A pesquisa, de abordagem quantitativa e de perspectiva descritivo-exploratória, coletou dados através da readiness for interprofessional learning scale, adaptada para o português do Brasil. Os resultados indicam que há disponibilidade para o trabalho em equipe e a colaboração. Também foram encontrados percentuais significativos relacionados à identidade profissional, o que indica disponibilidade para a aprendizagem interprofissional, embora aspectos relacionados à competição tenham aparecido através de percentuais menores de concordância em relação à aprendizagem compartilhada e interdependência das práticas profissionais. Para a atenção centrada no usuário também foram encontrados resultados que indicam boa disponibilidade entre os participantes; porém, aspectos relacionados à colaboração do usuário na produção dos serviços de saúde ainda expressam a tendência de uma lógica centrada nos profissionais. Conclui-se que há disponibilidade positiva para a educação interprofissional, que precisa ser cada vez mais estimulada nas políticas e estratégias de reformas curriculares. Saúde interprofissional pesquisa descritivoexploratória, descritivoexploratória descritivo exploratória, exploratória descritivo-exploratória scale Brasil profissional profissionais participantes porém Concluise Conclui se curriculares

Resumo A interprofissionalidade foi tema central do nono edital do Programa de Educação pelo Trabalho para a Saúde. O objetivo deste estudo foi descrever a disponibilidade dos estudantes que participaram do programa para a aprendizagem interprofissional. A pesquisa, de abordagem quantitativa e de perspectiva descritivo-exploratória, coletou dados através da readiness for interprofessional learning scale, adaptada para o português do Brasil. Os resultados indicam que há disponibilidade para o trabalho em equipe e a colaboração. Também foram encontrados percentuais significativos relacionados à identidade profissional, o que indica disponibilidade para a aprendizagem interprofissional, embora aspectos relacionados à competição tenham aparecido através de percentuais menores de concordância em relação à aprendizagem compartilhada e interdependência das práticas profissionais. Para a atenção centrada no usuário também foram encontrados resultados que indicam boa disponibilidade entre os participantes; porém, aspectos relacionados à colaboração do usuário na produção dos serviços de saúde ainda expressam a tendência de uma lógica centrada nos profissionais. Conclui-se que há disponibilidade positiva para a educação interprofissional, que precisa ser cada vez mais estimulada nas políticas e estratégias de reformas curriculares.

Abstract Interprofessionality was the central theme of the ninth call for proposals of the Education by Working for Health Program. The objective of this study was to describe the readiness of students who participated in the program for interprofessional learning. The research, of a quantitative approach and descriptive-exploratory perspective, collected data by applying the readiness for interprofessional learning scale (RIPLS), adapted for Brazilian Portuguese. The results indicate an important readiness for teamwork and collaboration. Relevant percentages were also found regarding professional identity, indicating good readiness for interprofessional learning, although aspects related to competition appeared in lower percentages of agreement regarding shared learning and interdependence of professional practices. For user-centered care, results were also found indicating good readiness among participants; however, aspects related to the collaboration of the user in the production of health services still express the tendency of a professional-centered logic. In conclusion, there is a positive readiness for interprofessional education, which needs to be increasingly stimulated in policies and strategies of curricular reforms.

Abstract Hyperinformation, conspiracy theories, algorithms, fake news, fake science, deep fake, post-truth, hate culture, are terms that make up the informational scenario of today regarding disinformation, as a concept and mediating process of contemporaneity. Facing this conjuncture, several spheres of society are challenged to conduct relations and processes that can counteract this reality. In this mission, schools, universities and other educational centers stand out, which have a preponderant role in the development of a critical sense that guides a public opinion marked by a common commitment to ethics, freedom and rationality, capable of facing up to disinformation. In this sense, although faced with a reality of professional devaluation, low salaries, and a lag in the supply of training, teachers play an important role by acting as mediators between knowledge and people, enabling the strengthening of citizenship. Based on this reality, several areas of knowledge have presented contributions in order to understand this potential to face the disinformation conjuncture in the school and academic environment with the active participation of teachers. Although they seem to discuss this phenomenon from different perspectives, some theoretical fields may have complementary conceptual and epistemological approaches. So, the aim of this study is to discuss the possibilities of using an interdominial construct between Critical Information Competence (CCI) and Educommunication in the educational field; and to propose a sequence of educommunicative activities in teacher education.

Resumo Hiperinformação, teorias da conspiração, algoritmos, fake news, fake science, deep fake, pós-verdade, cultura do ódio, são termos que compõem o cenário informacional da atualidade no que concerne à desinformação, enquanto conceito e processo mediador da contemporaneidade. Diante dessa conjuntura, diversas esferas da sociedade são desafiadas a conduzir relações e processos que possam contrapor essa realidade. Destacam-se, nessa missão, escolas, universidades e demais centros educacionais, que possuem um papel preponderante para o desenvolvimento do senso crítico que norteie uma opinião pública balizada pelo compromisso comum com a ética, a liberdade e a racionalidade, capaz de fazer frente à desinformação. Neste sentido, embora confrontados com uma realidade de desvalorização profissional, baixos salários e defasagem quanto à oferta de aperfeiçoamentos, os professores cumprem uma função importante ao atuar como mediadores entre o conhecimento e as pessoas, possibilitando o fortalecimento da cidadania. A partir dessa realidade, diversas áreas do conhecimento têm apresentado contributos no sentido de entender esse potencial de enfrentamento à conjuntura de desinformação no ambiente escolar e acadêmico com a participação ativa dos docentes. Embora pareçam discutir esse fenômeno a partir de diferentes perspectivas, alguns domínios teóricos podem possuir aproximações conceituais e epistemológicas complementares. Assim, o objetivo deste estudo é dialogar sobre as possibilidades de utilização de um constructo interdominial entre Competência Crítica em Informação (CCI) e a educomunicação no âmbito educacional; e propor uma sequência de atividades educomunicativas na formação de professores.

Abstract The Early Cretaceous volcanic Jaguarão Formation formed duringthe early stages of Gondwana breakup. These felsic rocks characteristically enclose numerous crustal xenoliths. Fieldwork, petrographic studies, and laser ablation multicollector ion coupled plasma mass spectrometer (LA-ICP-MS) U-Pb analyses were carried out to evaluate the xenoliths of the Jaguarão Formation. A base-to-top distribution of xenoliths in the different flows of the volcanic pile indicates that earlier flows incorporated centimeter-sized fragments of local underlying gneiss, granite, and quartz veins, with limited assimilation. In the middle part of the volcanic pile, the size of the xenoliths is smaller and assimilation textures are more frequent. At this same level, reequilibrated orthopyroxene and plagioclase antecrysts were recognized, suggesting fractionation coeval with assimilation in a lower magmatic chamber prior to extrusion. At the top, no visible xenoliths occur. U-Pb ages of the zircon xenocrysts served as a proxy for assessing the crust underlying the volcanic rocks. Most of the ages obtained are similar to the ages of the Eastern Dom Feliciano Belt cropping out nearby, ranging from 680 to 620 Ma, with a subordinate group ranging from 580 to 570 Ma, suggesting a shallow crust contribution. The presence of few Paleoproterozoic and Mesoproterozoic (1.0-1.2 Ma) zircons, however, suggeststhat the underlying terrain may be more complex..

Abstract This study evaluated the influence of non-thermal argon plasma applied to dentin on the shear strength of two adhesive systems. Ninety tooth fragments were embedded in epoxy resin and distributed into experimental groups (n=15): G1 and G4 - adhesive systems applied according to the manufacturers’ instructions; G2 and G5 - dentin treated with non-thermal argon plasma for 30 seconds before hybridization; G3 and G6 - dentin treated with non-thermal argon plasma for 30 seconds after hybridization. Cylinders were made with composite resin in the adhesive area, and the specimens were submitted to the shear strength test. Higher values were observed when applying the plasma treatment after hybridization (G1: 26.51 MPa, G2: 29.22 MPa, G3: 30.27 MPa, G4: 22.66 MPa, G5: 28.33 MPa, G6: 29.32 MPa). The treatment with non-thermal argon plasma significantly increased the shear strength values regardless of the application time.

Abstract The Cr-rich Jacurici Complex is located at the limit between the Serrinha Block and the Salvador-Curaçá Belt, Northeastern São Francisco Craton. In order to better understand the age span of magmatism and tectonism, we have studied a basement high-grade charnockite orthogneiss, a metanorite of the Complex and a crosscuting undeformed quartz-feldspar pegmatite. For the orthogneiss, SHRIMP U-Pb ages of zircon cores and overgrowth rims yielded, 2966 ± 9 Ma for crystallization and 2091 ± 10 Ma for metamorphism, respectively. Zircons from the metanorite show internal textures consistent with high grade metamorphism. The U-Pb LA-ICP-MS age determination provided a 2099 ± 6 Ma metamorphic age for the Jacurici Complex, indicating it was already emplaced during amalgamation around 2.1 Ga. Zircons from the undeformed quartz-feldspar pegmatite provided a LA-ICP-MS U-Pb age of 2083 ± 11Ma, marking the end of the N-S transcurrence. The magmatic Jacurici Complex age remains undefined, but is equal to, or older than, 2.1 Ga. Therefore, possible correlations with other mafic-ultramafic intrusions, such as the Cu-rich Caraíba Complex, should be reassessed. Our results indicate that the N-S transcurrence ended earlier in the Jacurici Complex region than in the northwestern area of the Salvador-Curaçá belt.

Resumo O objetivo deste estudo foi avaliar o desgaste de superfície, a presença de microtrincas e irregularidades superficiais dos instrumentos WaveOne (WO) e WaveOne Gold (WOG) antes e após múltiplos usos. Oito instrumentos Primary dos sistemas WO e WOG foram avaliados, cada um utilizado no preparo de seis canais mesiais de molares inferiores humanos extraídos. A superfície dos instrumentos foi avaliada antes do uso (T0), após a instrumentação de três (T1) e seis (T2) canais radiculares. O desgaste de superfície foi analisado utilizando um perfilômetro ótico tridimensional e a presença de microtrincas e irregularidades superficiais foram avaliadas usando um microscópio eletrônico de varredura de bancada. O teste de Friedman foi usado para avaliar o desgaste de superfície e o teste de Kruskal-Wallis para avaliar a presença de microtrincas e irregularidades superficiais, com nível de significância de 5%. Houve um aumento significativo no desgaste em ambos os grupos em T2, comparado a T0 (p=0.0003). O desgaste de superfície após a instrumentação de seis canais (T2-T0) foi estatisticamente maior no grupo WOG que no grupo WO (p=0.02), onde a presença de microtrincas foi estatisticamente maior e aumentou após os múltiplos usos (p<0.05). A presença de irregularidades na superfície da lamina de corte antes e após o uso aumento significativamente no grupo WOG comparado ao grupo WO (p<0.05). Desgaste da lâmina de corte, microtrincas e irregularidades superficiais foram observadas na topografia de superfície de todos os instrumentos após os múltiplos usos. Essas alterações na superfície podem afetar a eficiência de corte dos instrumentos WOG e amentar o risco de fratura dos instrumentos WO.

Abstract The aim of this study was to evaluate surface wear, presence of microcracks and surface irregularities of WaveOne (WO) and WaveOne Gold (WOG) instruments before and after multiple uses. Eight Primary instruments of the WO and WOG systems were evaluated, each one was used to prepare six mesial canals of extracted human mandibular molars. The surface of the instruments was evaluated before use (T0), after instrumentation of three (T1) and six (T2) root canals. Surface wear was analyzed using a three-dimensional optical profiler and the presence of microcracks and surface irregularities were evaluated using a tabletop scanning electron microscopy. The Friedman test was used to assess surface wear and Kruskal-Wallis test to evaluate the presence of microcracks and surface irregularities, with a 5% significance level. There was a significant increase in wear in both groups at T2, compared to T0 (p=0.0003). The surface wear after instrumentation of six canals (T2-T0) was statistically greater in the WOG group, than in the WO group (p=0.02), where the presence of microcracks was significantly greater and increased after multiple uses (p<0.05). The presence of surface irregularities in the cutting blade before and after use was statistically greater in the WOG group than WO group (p<0.05). Wear of the cutting blade, microcracks and surface irregularities were observed on the surface topography of all the instruments after multiple uses. These surface changes may affect the cutting efficiency of WOG files and increase the risk of fracture of WO files.

Resumo A vitrificação de espermatozoides é uma técnica que apresenta grande potencial para criopreservação de material genético, e sua eficácia tem sido superior aos métodos convencionais em algumas espécies. No entanto, existem poucos estudos sobre sua eficiência com sêmen ejaculado de carneiros e o uso da galactose como crioprotetor extracelular durante a vitrificação. Objetivou-se com este estudo avaliar o efeito da galactose (0,01 M), associada ou não ao glicerol (3% e 7%), em meio comercial (Steridyl® - controle), na criopreservação de espermatozoides de carneiros pelo método de palhetas, comparando o método clássico de congelação e a vitrificação. Ejaculados de seis carneiros da raça Dorper em idade reprodutiva foram coletados com vagina artificial, aliquotados, diluídos individualmente (100 × 106 espermatozoides/mL) nos meios testados, envasados em palhetas de 0,25 mL e submetidos à congelação clássica ou vitrificação. Foram analisadas a cinemática, morfologia, morfometria, viabilidade, integridade física e funcional da membrana espermática. A congelação clássica obteve melhores resultados de motilidade total e progressiva do que a vitrificação nos quatro extensores testados, uma vez que as amostras vitrificadas não apresentaram motilidade pós-reaquecimento (p < 0,05). A adição de galactose ou glicerol ao meio comercial não trouxe efeito benéfico tanto para a vitrificação quanto congelação clássica.

Abstract Sperm vitrification is a technique with great potential for cryopreservation of genetic material, with superior effectiveness compared to conventional methods in some species. However, few studies have shown its efficiency with ejaculated sperm of rams and the use of galactose as an extracellular cryoprotectant during vitrification. This study aimed to evaluate the effect of galactose (0.01 M), with or without glycerol addition (3% and 7%) in a commercial extender (Steridyl® - control) for ram sperm cryopreservation in straws, comparing the classic freezing method and vitrification. Ejaculates from six breeding soundness Dorper rams were collected with an artificial vagina, aliquoted, individually diluted (100 × 106 sperm/mL) on extenders tested, loaded into 0.25 mL straws, and subjected to a classic freezing method or vitrification. Sperm kinematics, morphology, morphometry, viability, and physical and functional integrity of the sperm membrane were evaluated. The classic freezing method resulted in higher total and progressive motility than vitrification, as no motility was detected in vitrified samples after rewarming (p<0.05). The addition of galactose or glycerol to the commercial medium did not benefit both vitrification and the classic freezing method.

Abstract Although equine blastocysts ≤ 300 µm in diameter can be successfully vitrified, larger equine blastocysts are not good candidates for cryopreservation. As Na+, K+-ATPase is involved in maintaining blastocyst expansion, perhaps inhibition of this enzyme would be a viable method of reducing blastocyst diameter prior to cryopreservation. Objectives were to evaluate effects of ouabain-induced inhibition of Na+, K+-ATPase in equine blastocysts. Sixteen mares were ultrasonographically monitored, given deslorelin acetate to induce ovulation, and inseminated. Embryos (D7 and D9) were harvested and Na+, K+-ATPase inhibited for 1 or 6 h by exposure to 10-6 M ouabain, either natural ouabain or conjugated to fluorescein (OuabainFL), during incubation at 37° C. Evaluations included morphometric characteristics (bright field microscopy) and viability (Hoescht 33342 + propidium iodide). Blastocysts incubated for 6 h in Holding medium + ouabain (n=3) had, on average, a 45.7% reduction in diameter, with adverse morphologic features and no re-expansion after subsequent incubation in Holding medium for 12 h. In subsequent studies, even a 1-h exposure to Ouabain or OuabainFL, caused similar reductions, namely 38.7 ± 6.7% (n=5) and 33.6 ± 3.3% (n=7) for D7 and D9 blastocysts, respectively. Ouabain binding was confirmed after OuabainFL exposition and all embryos (n=12) lost viability. We concluded that Na+, K+-ATPase inhibition with ouabain caused death of equine blastocysts and therefore was not a viable method of reducing blastocyst size prior to cryopreservation.

RESUMO Objetivos: comparar a efetividade do sistema automatizado de distribuição descentralizada de medicamentos por armário. Métodos: trata-se de estudo de efetividade embasado por revisão sistemática, norteada pela questão: Para pacientes internados em unidades hospitalares, o uso de dispensário eletrônico é efetivo para a redução de erros de medicação comparado à dispensação manual por dose unitária? O conjunto da evidência foi avaliado pelo Grading of Recommendations Assessment, Development and Evaluation, sendo o instrumento Preferred Reporting Items for Systematic Reviews and Meta-Analyses usado no relatório. Resultados: a amostra foi composta por 15 estudos e nenhum deles comparou diretamente as tecnologias, contudo, a metanálise revelou que não existe diferença de efetividade entre elas [OR 1.03 IC 95% (0,12 - 8,99)]. Conclusões: conclui-se que a recomendação é fraca a favor do dispensário eletrônico.

ABSTRACT Objectives: to compare the effectiveness of the decentralized automated drug dispensing system with pockets. Methods: an effectiveness study based on a systematic review guided by the question: for patients admitted to hospital units, is the use of automated drug dispensing effective for reducing medication errors when compared to manual unit dose dispensing? The evidence was evaluated by the Grading of Recommendations Assessment, Development and Evaluation and the Preferred Reporting Items for Systematic Reviews and Meta-Analyses instrument, used in the report. Results: the sample was composed of 15 studies and none of them directly compared both technologies; however, the meta-analysis showed that there is no difference in effectiveness between them [OR 1.03 95%CI (0,12 - 8,99)]. Conclusions: the conclusion is that the recommendation in favor of the automated dispensing system is weak.

RESUMEN Objetivos: comparar la eficacia del sistema automatizado de distribución descentralizada de medicamentos por armario. Métodos: se trata de un estudio de efectividad basado en una revisión sistemática guiada por el tema: Para los pacientes ingresados en los hospitales, ¿el uso del dispensario electrónico es eficaz para reducir errores de medicación en comparación con la dispensación manual por dosis unitaria? El conjunto de la evidencia se evaluó según los sistemas GRADE (evaluación de la calidad de la evidencia y graduación de la fuerza de las recomendaciones) y PRISMA (elementos de informes preferidos para los protocolos de revisión sistemática y metaanálisis) usado en el informe. Resultados: la muestra estaba compuesta de 15 estudios y ninguno comparó directamente las tecnologías; sin embargo, el metaanálisis mostró que no existe diferencia de la eficacia entre ellas [OR 1.03 IC 95% (0,12 - 8,99)]. Conclusiones: se ultima que la recomendación es débil a favor del dispensario electrónico.

ABSTRACT Objectives: to compare the effectiveness of the decentralized automated drug dispensing system with pockets. Methods: an effectiveness study based on a systematic review guided by the question: for patients admitted to hospital units, is the use of automated drug dispensing effective for reducing medication errors when compared to manual unit dose dispensing? The evidence was evaluated by the Grading of Recommendations Assessment, Development and Evaluation and the Preferred Reporting Items for Systematic Reviews and Meta-Analyses instrument, used in the report. Results: the sample was composed of 15 studies and none of them directly compared both technologies; however, the meta-analysis showed that there is no difference in effectiveness between them [OR 1.03 95%CI (0,12 - 8,99)]. Conclusions: the conclusion is that the recommendation in favor of the automated dispensing system is weak.

RESUMEN Objetivos: comparar la eficacia del sistema automatizado de distribución descentralizada de medicamentos por armario. Métodos: se trata de un estudio de efectividad basado en una revisión sistemática guiada por el tema: Para los pacientes ingresados en los hospitales, ¿el uso del dispensario electrónico es eficaz para reducir errores de medicación en comparación con la dispensación manual por dosis unitaria? El conjunto de la evidencia se evaluó según los sistemas GRADE (evaluación de la calidad de la evidencia y graduación de la fuerza de las recomendaciones) y PRISMA (elementos de informes preferidos para los protocolos de revisión sistemática y metaanálisis) usado en el informe. Resultados: la muestra estaba compuesta de 15 estudios y ninguno comparó directamente las tecnologías; sin embargo, el metaanálisis mostró que no existe diferencia de la eficacia entre ellas [OR 1.03 IC 95% (0,12 - 8,99)]. Conclusiones: se ultima que la recomendación es débil a favor del dispensario electrónico.

RESUMO Objetivos: comparar a efetividade do sistema automatizado de distribuição descentralizada de medicamentos por armário. Métodos: trata-se de estudo de efetividade embasado por revisão sistemática, norteada pela questão: Para pacientes internados em unidades hospitalares, o uso de dispensário eletrônico é efetivo para a redução de erros de medicação comparado à dispensação manual por dose unitária? O conjunto da evidência foi avaliado pelo Grading of Recommendations Assessment, Development and Evaluation, sendo o instrumento Preferred Reporting Items for Systematic Reviews and Meta-Analyses usado no relatório. Resultados: a amostra foi composta por 15 estudos e nenhum deles comparou diretamente as tecnologias, contudo, a metanálise revelou que não existe diferença de efetividade entre elas [OR 1.03 IC 95% (0,12 - 8,99)]. Conclusões: conclui-se que a recomendação é fraca a favor do dispensário eletrônico.

ABSTRACT The present study provides a reflective analysis on the development of online assistive technologies that support nursing care for people with disabilities, based on Falkembach’s instructional design model. Reflective study conducted in April 2018 through the online institutional repository of the Graduate Program in Nursing of Universidade Federal do Ceará. Studies on technologies from the last five years involving people with sensory disabilities were selected. Four studies on the construction of online assistive technologies were analyzed, and three courses and one educational leaflet addressed prevention and health promotion in breast health, high blood pressure, sexual and reproductive health and prevention of sexual violence with accessible and inclusive language. It was concluded that nurses should use rigorous and effective methods in the construction of assistive technologies, observe all the steps the model, avoiding errors and optimizing results.

RESUMEN Estudio que presenta un análisis reflexivo sobre el desarrollo de tecnologías de atención online que respaldan la atención de enfermería a las personas con discapacidades, en base al modelo de diseño instruccional de Falkembach. Estudio reflexivo, realizado en abril de 2018 utilizando el repositorio online institucional del programa de posgrado en enfermería de la Universidade Federal do Ceará. Fueron seleccionadas investigaciones sobre tecnologías de los últimos cinco años en referencia a personas con carencias sensoriales. Se analizaron cuatro estudios de construcción de tecnologías de atención online: tres cursos y una libreta sobre prevención y promoción de salud en salud mamaria, hipertensión arterial, salud sexual y reproductiva y prevención de la violencia sexual con lenguaje sencillo e inclusivo. Se concluyó en que el enfermero debe utilizar métodos rigurosos y eficaces en la construcción de tecnologías de atención y respetar las etapas del modelo, evitando errores y optimizando resultados.

RESUMO Este estudo apresenta análise reflexiva sobre desenvolvimento de tecnologias assistivas online, que subsidiam o cuidado de enfermagem à pessoa com deficiência, com base em modelo de design instrucional de Falkembach. Estudo reflexivo, realizado em abril de 2018, através do repositório institucional online do Programa de Pós-Graduação em Enfermagem da Universidade Federal do Ceará. Selecionaram-se pesquisas sobre tecnologias dos últimos cinco anos envolvendo pessoas com deficiência sensorial. Foram analisadas quatro pesquisas de construção de tecnologias assistivas online, sendo três cursos e uma cartilha, sobre prevenção e promoção da saúde na saúde mamária, hipertensão arterial, saúde sexual e reprodutiva e prevenção da violência sexual com linguagem acessível e inclusiva. Concluiu-se que o enfermeiro deve utilizar métodos rigorosos e eficazes na construção de tecnologias assistivas, obedecer às etapas do modelo, evitando erros e otimizando resultados.

Resumen El Batolito de Acandí es un cuerpo intrusivo con amplias variaciones composicionales (González y Londoño, 2002) que data del Oligoceno (Restrepo y Toussaint, 1976), a su vez intruído por cuerpos subvolcánicos de andesitas, dacitas, y diques de basaltos. Debido a la diferencia composicional de este cuerpo en la cordillera Occidental, se realiza la integración e interpretación de datos del análisis petrográfico, geoquímico e isotópico de muestras recolectadas en la parte norte del Golfo de Urabá entre los municipios de Acandí y Unguía en el departamento de Chocó. En esta zona, las rocas del Batolito son gabros: rocas melanocráticas, masivas, equigranulares de grano fino a medio, subhedrales, de textura fanerítica; y las de los cuerpos subvolcánicos y diques son: rocas leucocráticas, masivas, inequigranulares, de grano fino a medio, subhedrales, con textura porfirítica y rocas melanocráticas afaníticas (basaltos). Petrografía detallada muestra que las rocas del Batolito son compuestas por plagioclasa, piroxenos y anfíboles, como accesorios pirita diseminada, apatita, magnetita e ilmenita. Son rocas holocristalinas, melanocráticas, inequigranulares, subhedrales, de fino a groso granulares, con presencia de texturas ofíticas y subofíticas, con coronas de reacción y zonación en plagioclasas. Las rocas subvólcanicas que intruyen el batólito son basaltos afaníticos, dacitas y andesitas con texturas porfiríticas, con plagioclasa y hornblenda como minerales principales. Son inequigranulares, de tamaño muy fino a grueso, con texturas cúmulo-porfiríticas, vesiculares y amigdulares. Los análisis geoquímicos e isotópicos indican que tanto las rocas del batolito como las de los cuerpos que lo intruyen, son de afinidad subalcalina de la serie calco-alcalina de bajo a medio K, metaluminosas, con enriquecimiento en elementos de tierras raras leves en relación a las tierras raras pesadas. Los datos geoquímicos e isotópicos de Nd y Sr sugieren que estas rocas se forman a partir de procesos en arcos de islas, asociados a zonas de subducción, siendo posteriormente acrecionadas al margen continental.

Abstract The Acandi’s batholith is a large intrusive body with a wide compositional variation (Gonzalez and Londoño, 2002) dating from the Oligocene (Restrepo and Toussaint, 1976), and intruded by subvolcanic andesites and dacites bodies and basalt dikes. Due to the compositional difference of this body in the Western Cordillera, it is performed integration and interpretation of new petrographic, geochemical and isotopic data from samples collected in the northern Gulf of Urabá between the towns of Acandí and Unguía it is done in Choco department. For this area, batholith rocks are gabbros: melanocratic rocks, massive, equigranular fine to medium grained, subhedral, phaneritic texture; and the subvolcanic bodies and dikes are: leucocratic, massive and inequigranular rocks, fine to medium grained, subhedral, with sporphyritic texture and aphanitic melanocratic rocks (basalts). Detailed petrography shows that the rocks from the Batolith are constituted by plagioclase, pyroxene and amphibole, with disseminated pyrite, apatite, magnetite and ilmenite as accessory phases. The batholith rocks are holocrystalline, melanocratic, inequigranular, subhedral, from fine to granular roughly, with the presence of ophitic and subophitic textures, with reaction rings (coronas) and zoning in plagioclase. The intrusive subvolcanic rocks that crosscut the Batholith are afanitic basalts, dacites, and andesites with porphiritic textures, having plagioclase and hornblende as main minerals. They are inequigranular, very fine to coarse grained, with glomeroporphyritic texture and also vesicular and amygdular textures. Geochemical and isotopic analyses indicate that both batholiths and intrusive rocks are sub-alkaline from the calc-alkaline series of low to medium K, metaluminous with light rare earth elements enrichment in relation to the heavy rare earth elements. The geochemical and Nd and Sr isotopic data suggest that these rocks are formed in island arcs, associated with subduction zones, being later added to a continental margin.