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Practical application of laser reflectance confocal microscopy in the follow-up of patients with lentigo maligna undergoing treatment with Imiquimod
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Ishioka, Priscila

; Costa, Lilian Lemos

; Maia, Marcus

Anais Brasileiros de Dermatologia

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aug 2022, Volume 97 N. 4 Pages 520 - 522

Abstract: En | Text: En | PDF: En

https://doi.org/10.1016/j.abd.2021.01.008

Plantar Spitz nevus mimicking melanoma
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Valinoto, Guilherme Camargo Julio

; Santos, Felipe Henrique Yazawa

; Lellis, Rute Facchini

; Maia, Marcus

Anais Brasileiros de Dermatologia

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aug 2022, Volume 97 N. 4 Pages 545 - 547

Abstract: En | Text: En | PDF: En

https://doi.org/10.1016/j.abd.2020.10.024

ANOMALIAS DE FORMA E DE CONTEÚDO EM PORTUGUÊS BRASILEIRO: UM ESTUDO PRELIMINAR DE RASTREAMENTO OCULAR DA LEITURA E DE AVALIAÇÃO DE ACEITABILIDADE
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Maia, Marcus

; Nascimento, Guilherme

Cadernos de Tradução

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dec 2020, Volume 40 N. spe2 Pages 45 - 73

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo O presente estudo usou a metodologia de rastreamento ocular para investigar em que medida a leitura de frases em português brasileiro pode diferir em relação a anomalias gramaticais e semânticas e como essas frases são avaliadas quanto à sua boa formação, tomando-se como controle frases bem formadas gramatical e semanticamente. A partir da análise dos dados on-line, foi possível identificar que as sentenças que apresentam anomalias de traço de concordância de número no sintagma nominal, ainda que melhor aceitas na medida off-line do que as frases com anomalias semânticas pelos falantes escolarizados da língua, são processadas de forma inicialmente mais custosa em termos dos padrões de fixação e de refixação. Avalia-se que os resultados obtidos aduzem evidências em favor dos modelos estruturais de processamento de frases.

Abstract The present study uses the eye tracking methodology to investigate to what extent the reading of sentences in Brazilian Portuguese may differ in relation to grammatical and semantic anomalies and how these sentences are evaluated for their good formation, taking as control syntactically and semantically well-formed sentences. The analyses of the on-line data, allowed us to identify that sentences that present anomalous number agreement features in the object noun phrase are more costly in terms of fixation and refixation patterns than the semantic anomalous sentences, even though they may be better accepted by educated speakers in the off-line measure than sentences with semantic anomalies. It is argued that the results provide evidence in favor of structural models of sentence processing.

https://doi.org/10.5007/2175-7968.2020v40nesp2p45 249 downloads

Relações Lógico-Inferenciais no Uso dos Conectivos porque e já que: um Estudo Comparativo entre Ensino Fundamental e Ensino Superior
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Santos, Sabrina Lopes dos

; Garcia, Daniela Cid de

; Maia, Marcus

Ilha do Desterro

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dec 2019, Volume 72 N. 3 Pages 123 - 137

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo: Este artigo apresenta um estudo comparativo entre Ensino Fundamental e Ensino Superior investigando o uso dos conectivos porque e já que em sentenças com relações inferenciais de causa estabelecidas via raciocínio lógico indutivo e dedutivo. Como a aquisição de alguns conectivos tem relação com a escolaridade e com a consequente exposição à modalidade escrita, este trabalho pode contribuir para levantar questões sobre a relação entre a aquisição dessa modalidade e sua influência no modo como interpretamos relações lógico-inferenciais. Neste artigo, apresentamos um teste de julgamento de escolha forçada em que os participantes deveriam escolher entre os conectivos já que e porque ao serem apresentados a sentenças com relações de causa direta e indireta. Nossa hipótese foi a de que, em relações de causa indireta, indivíduos com maior experiência em leitura optariam por já que, mas indivíduos com pouca experiência deveriam escolher majoritariamente porque em ambos os casos.

Abstract: This paper presents a comparative study between Elementary School and Undergraduate Education investigating the use of connectives já que and porque in sentences with inferential causal relations established through inductive and deductive logical reasoning. As the acquisition of some connectives is related to schooling and consequent exposure to the written modality, this work can contribute to raising questions about the relationship between the acquisition of this modality and its influence on the way we interpret logical-inferential relations. In this paper, we present a forced-choice judgment test in which participants should choose between the connectives já que and porque when they are exposed to sentences with direct and indirect causal relationships. Our hypothesis was that, in indirect cause relationships, individuals with more experience in reading would choose já que, but individuals with little experience should choose mainly porque in both cases.

https://doi.org/10.5007/2175-8026.2019v72n3p123 559 downloads

PROCESSAMENTO DE FRASES E CONTEXTO DISCURSIVO
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MAIA, Marcus

Alfa: Revista de Linguística (São José do Rio Preto)

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dec 2019, Volume 63 N. 3 Pages 559 - 582

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Investiga-se o curso temporal dos subprocessos da compreensão de frases, procurando-se determinar se o processador é estritamente sintático em sua análise inicial ou se já acessa informações de natureza semântica e discursiva a tempo de influenciar a análise sintática. São reportados dois estudos com falantes de português brasileiro, para aferir efeitos de contexto discursivo no processamento. O primeiro revisita o processamento de Sintagmas Preposicionais ambíguos e encontra efeito do discurso prévio apenas nas medidas finais, que monitoram a interpretação. O segundo usa a técnica de rastreamento ocular (eye-tracking) para aferir a busca de antecedente para o sujeito de oração com verbo no infinitivo flexionado, encontrando efeito do discurso prévio tanto na medida final ou off-line, quanto na medida on-line. Discutem-se possíveis razões para as diferenças entre os efeitos de informações discursivas nos dois experimentos.

ABSTRACT The time course of sentence comprehension subprocesses is investigated in order to assess whether the parser is strictly syntactic in its early phases or whether semantic, pragmatic and discursive information is quickly accessed in time to influence the syntactic analysis. Two experimental studies are reported testing speakers of Brazilian Portuguese, to assess the effects of discursive context in sentence processing. The first experiment revisits the processing of ambiguously attached Prepositional Phrases and finds effects of the previous discourse only in the final off-line measures, which monitor interpretation. The second experiment uses the eye-tracking technique to gauge the antecedent search for the subject of clauses with inflected infinitive verbs, detecting effects of the previous discourse both in the final off-line measure and in the on-line gaze fixation average times. Possible reasons for differences between the effects of discursive information in the two experiments are discussed.

https://doi.org/10.1590/1981-5794-1911-4 1754 downloads

Albinism: epidemiology, genetics, cutaneous characterization, psychosocial factors
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Marçon, Carolina Reato

; Maia, Marcus

Anais Brasileiros de Dermatologia

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oct 2019, Volume 94 N. 5 Pages 503 - 520

Abstract: En | Text: En | PDF: En

Abstract Oculocutaneous albinism is an autosomal recessive disease caused by the complete absence or decrease of melanin biosynthesis in melanocytes. Due to the reduction or absence of melanin, albinos are highly susceptible to the harmful effects of ultraviolet radiation and are at increased risk of actinic damage and skin cancer. In Brazil, as in other parts of the world, albinism remains a little known disorder, both in relation to epidemiological data and to phenotypic and genotypic variation. In several regions of the country, individuals with albinism have no access to resources or specialized medical care, and are often neglected and deprived of social inclusion. Brazil is a tropical country, with a high incidence of solar radiation during the year nationwide. Consequently, actinic damage and skin cancer occur early and have a high incidence in this population, often leading to premature death. Skin monitoring of these patients and immediate therapeutic interventions have a positive impact in reducing the morbidity and mortality associated with this condition. Health education is important to inform albinos and their families, the general population, educators, medical professionals, and public agencies about the particularities of this genetic condition. The aim of this article is to present a review of the epidemiological, clinical, genetic, and psychosocial characteristics of albinism, with a focus in skin changes caused by this rare pigmentation disorder.

https://doi.org/10.1016/j.abd.2019.09.023 7946 downloads

Acral melanoma: considerations about the surgical management of this tumor
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Zyman, Lívia Mesquita

; Cunha, José Antônio Jabur da

; Gimenez, Andrea Ortega

; Maia, Marcus

Anais Brasileiros de Dermatologia

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oct 2019, Volume 94 N. 5 Pages 632 - 633

Abstract: En | Text: En | PDF: En

https://doi.org/10.1016/j.abd.2019.09.019 376 downloads

Vertical plane ex vivo dermoscopy: a novel dermoscopic technique. A preliminary study
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Maia, Marcus

; Amadio, Camila Ribeiro

; Morales, Andrezza Garcia

; Lellis, Rute Facchini

Anais Brasileiros de Dermatologia

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dec 2018, Volume 93 N. 6 Pages 899 - 901

Abstract: En | Text: En | PDF: En

Abstract: Dermoscopic examination allows visualization of horizontal images on the skin, showing well-defined patterns. The authors propose ex vivo dermoscopic visualization using a vertical view of skin sections. The new image clearly distinguishes the stratum corneum, epidermis, and dermis as well as the anatomical location of the pigment. Will this new approach be useful in dermoscopic diagnosis? Further studies are needed.

https://doi.org/10.1590/abd1806-4841.20187863 611 downloads

Processamento de interrogativas-QU em Português Brasileiro: evidências de eyetracking e EEG
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Oliveira, Fernando Lúcio de

; Maia, Marcus

; França, Aniela Improta

Letras de Hoje

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mar 2018, Volume 53 N. 1 Pages 24 - 38

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo: Este artigo trata do processamento de sentenças com interrogativas-QU de sujeito e de objeto em português brasileiro1 (PB). Especificamente, investigou-se a Assimetria Sujeito-Objeto nesse tipo de sentença, partindo-se de resultados anteriores com a técnica de leitura automonitorada (OLIVEIRA; MAIA, 2010; OLIVEIRA, 2013). Foram utilizadas as técnicas de rastreamento ocular (eyetracking) e eletroencefalografia (EEG) como ferramentas de diagnóstico do processamento linguístico em tempo real. O objetivo era buscar evidências sobre o modus operandi do parser durante o processamento das funções de sujeito e de objeto em sentenças interrogativas-QU no PB e verificar se há discrepâncias entre as técnicas utilizadas. Os resultados revelam diferenças interessantes, permitindo discernir os níveis de análise representacional, algorítmico e implementacional, na direção da clássica proposta de Marr (1982).

Abstract: This article deals with the processing of subject and object WH-sentences of Brazilian Portuguese (BP). Specifically, it investigates the subject/object asymmetry in this type of sentence, following previous results using self-paced reading technique (OLIVEIRA; MAIA, 2010; OLIVEIRA, 2013). Eyetracking and electroencephalography (EEG) techniques were used as diagnostic tools for real-time linguistic processing. The goal was to find evidence of the modus operandi of the parser during the processing of subject and object syntactic functions in Brazilian Portuguese WH-sentences and verify if there are discrepancies between the techniques. The results allow discerning the levels of representational, algorithmic and implementation analysis, in the direction of the classical proposal of Marr (1982).

https://doi.org/10.15448/1984-7726.2018.1.29040 726 downloads

10.

Synchronous conjunctival melanoma and lentigo maligna melanoma
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Volpini, Beatrice Mussio Fornazier

; Maia, Marcus

; Agi, Jorge

; Vital Filho, José

; Lellis, Rute Facchini

Anais Brasileiros de Dermatologia

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aug 2017, Volume 92 N. 4 Pages 565 - 567

Abstract: En | Text: En | PDF: En

Abstract: Lentigo maligna has an extensive and neoplastic character. It typically progresses slowly and may eventually develop into an invasive melanoma, which is called lentigo maligna melanoma. Ocular melanoma is the second most common type of melanoma. The uvea is the most common site of origin of ocular melanomas, while conjunctival melanoma accounts for about 1-5% of cases. In this article, we describe a rare case of synchronic conjunctival melanoma and lentigo maligna on the face.

https://doi.org/10.1590/abd1806-4841.20176015 1032 downloads

11.

Quality of life in patients with oculocutaneous albinism
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Maia, Marcus

; Volpini, Beatrice Mussio Fornazier

; Santos, Gabriela Alves dos

; Rujula, Maria Josefa Penon

Anais Brasileiros de Dermatologia

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aug 2015, Volume 90 N. 4 Pages 513 - 517

Abstract: En | Text: En | PDF: En

AbstractBACKGROUND:The social reality of the albino needs to be more studied in Brazil, as myths and social segregation regarding this illness are likely to be found in the country, with psychosocial and medical implications.OBJECTIVE:As this subject has not been referenced in previous scientific articles in Brazil, this research intends to evaluate the quality of life of the albinos that treated at our medical institution.METHODS:The quality of life was evaluated through the WHOQOL-BREF. Furthermore, two aspects of main relevance in the lives of the albinos were also objects of research, low vision and skin cancer. The sample consisted of forty oculocutaneous albinos and a control group of forty healthy individuals, matched by sex and age.RESULTS:Among the participants, 57.7% were between 18 and 40 years old, 28.2% were between 41 and 60, and 14.1% were over 60. 42.1% had skin cancer before the study, 18.4% had skin cancer during the study and 89.5% stated visual deficit. The results obtained in the questionnaires showed a statistically significant difference in the physical domain, with P < 0.001.CONCLUSION:Low vision combined with skin lesions and social stigma may contribute to disturbances in the quality of life of oculocutaneous albinos. The results presented in this study demonstrated the vulnerability of the affected individuals and the special care required by those patients, at the same time that the need for further research is highlighted in order to better elucidate the aspects related to albinism.

https://doi.org/10.1590/abd1806-4841.20153498 2131 downloads

12.

Evaluation of the therapeutic results of actinic keratosis treated with topical 5% fluorouracil by reflectance confocal laser microscopy: preliminary study
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Ishioka, Priscila

; Maia, Marcus

; Rodrigues, Sarita Bartholomei

; Marta, Alessandra Cristina

; Hirata, Sérgio Henrique

Anais Brasileiros de Dermatologia

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jun 2015, Volume 90 N. 3 Pages 426 - 429

Abstract: En | Text: En | PDF: En

Abstract Topical treatment for actinic keratosis with 5% fluorouracil has a recurrence rate of 54% in 12 months of follow-up. This study analyzed thirteen actinic keratoses on the upper limbs through confocal microscopy, at the time of clinical diagnosis and after 4 weeks of treatment with fluorouracil. After the treatment was established and evidence of clinical cure was achieved, in two of the nine actinic keratoses, confocal microscopy enabled visualization of focal areas of atypical honeycomb pattern in the epidermis indicating therapeutic failure. Preliminary data suggest the use of confocal microscopy as a tool for diagnosis and therapeutic control of actinic keratosis.

https://doi.org/10.1590/abd1806-4841.20153437 1201 downloads

13.

Brazilian Consensus on Photoprotection
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Schalka, Sérgio

; Steiner, Denise

; Ravelli, Flávia Naranjo

; Steiner, Tatiana

; Terena, Aripuanã Cobério

; Marçon, Carolina Reato

; Ayres, Eloisa Leis

; Addor, Flávia Alvim Sant'anna

; Miot, Helio Amante

; Ponzio, Humberto

; Duarte, Ida

; Neffá, Jane

; Cunha, José Antônio Jabur da

; Boza, Juliana Catucci

; Samorano, Luciana de Paula

; Corrêa, Marcelo de Paula

; Maia, Marcus

; Nasser, Nilton

; Leite, Olga Maria Rodrigues Ribeiro

; Lopes, Otávio Sergio

; Oliveira, Pedro Dantas

; Meyer, Renata Leal Bregunci

; Cestari, Tânia

; Reis, Vitor Manoel Silva dos

; Rego, Vitória Regina Pedreira de Almeida

Anais Brasileiros de Dermatologia

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dec 2014, Volume 89 N. 6 Pages 1 - 74

Abstract: En | Text: En | PDF: En

Brazil is a country of continental dimensions with a large heterogeneity of climates and massive mixing of the population. Almost the entire national territory is located between the Equator and the Tropic of Capricorn, and the Earth axial tilt to the south certainly makes Brazil one of the countries of the world with greater extent of land in proximity to the sun. The Brazilian coastline, where most of its population lives, is more than 8,500 km long. Due to geographic characteristics and cultural trends, Brazilians are among the peoples with the highest annual exposure to the sun. Epidemiological data show a continuing increase in the incidence of non-melanoma and melanoma skin cancers. Photoprotection can be understood as a set of measures aimed at reducing sun exposure and at preventing the development of acute and chronic actinic damage. Due to the peculiarities of Brazilian territory and culture, it would not be advisable to replicate the concepts of photoprotection from other developed countries, places with completely different climates and populations. Thus the Brazilian Society of Dermatology has developed the Brazilian Consensus on Photoprotection, the first official document on photoprotection developed in Brazil for Brazilians, with recommendations on matters involving photoprotection.

https://doi.org/10.1590/abd1806-4841.20143971 14207 downloads

14.

APRESENTAÇÃO
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Maia, Marcus

; Telles, Stella

DELTA: Documentação de Estudos em Lingüística Teórica e Aplicada

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2014, Volume 30 N. spe Pages 3 - 10

Abstract: Pt | Text: Pt | PDF: Pt

https://doi.org/10.1590/0102-44500266771486877 677 downloads

15.

Processamento da linguagem no Transtorno do Déficit de Atenção e Hiperatividade (TDAH)
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Albuquerque, Guiomar

; Maia, Marcus

; França, Aniela

; Mattos, Paulo

; Pastura, Giuseppe

DELTA: Documentação de Estudos em Lingüística Teórica e Aplicada

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2012, Volume 28 N. 2 Pages 245 - 280

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

O Transtorno do Déficit de Atenção/Hiperatividade (TDAH) é o diagnóstico psiquiátrico mais frequente entre crianças com problemas de aprendizagem. Os sujeitos com TDAH apresentam problemas de memória operacional, portanto, levantamos a hipótese de que o grupo com TDAH não apresentaria o mesmo desempenho em tarefas de leitura que o grupo controle. Realizamos cinco experimentos psicolinguísticos, utilizando metodologia on-line, com o objetivo de diferenciar o processamento da leitura do processamento metalinguístico e, desta forma, especificar a natureza da dificuldade dos portadores de TDAH. Ambos os grupos obtiveram índices de acertos similares, porém as latências foram significativamente maiores para o grupo de sujeitos com TDAH, demonstrando que eles têm a capacidade de chegar a um mesmo resultado, porém necessitam de mais tempo do que o grupo controle. Este resultado sugere que pode haver um problema de processamento da linguagem intrínseco ao TDAH.

Attention-Deficits/Hyperactivity Disorder (ADHD) is the most frequent psychiatric diagnosis in children with learning disorders. Individuals with ADHD usually present working memory difficulties. We raise the hypothesis that people with ADHD wouldn't have the same performance in reading tasks, compared to a control group. Five psycholinguistic experiments using on-line methodology were applied. The aim was to distinguish between the processing of reading and metalinguistic processing, in order to identify the nature of the linguistic impairments in ADHD volunteers. Both groups obtained similar accuracy rates, but latencies were significantly higher for the ADHD group than for the controls, demonstrating that ADHD subjects are able to achieve the same results, but that they need more time than the control group. This result suggests that there is a language processing problem intrinsic to ADHD individuals.

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