Objectives: Animal hoarding is a special manifestation of hoarding disorder, characterized by the accumulation of animals and failure to provide them with minimal care. The main objective of this systematic review is to evaluate the characteristics of animal hoarding, focusing on the profile of affected individuals and the features of accumulation behavior. Methods: A systematic search of the literature was conducted in the electronic databases MEDLINE, Scopus, and LILACS until October 2022. We included case series (n ≥ 10) and cross-sectional studies assessing animal hoarding. Results: A total of 374 studies were initially retrieved. Most studies were classified as having poor quality and significant risk of bias. A total of 538 individuals with animal hoarding were evaluated. These individuals were predominantly middle-aged, unmarried women who lived alone in urban areas. Most of their residences had unsanitary conditions. Recidivism rates varied from 13-41%. Cats and dogs were the main hoarded species, mostly acquired through unplanned breeding, and disease, injury, behavioral problems, and a lack of hygiene were characreristic of their condition. Animal carcasses were found in up to 60% of the properties. Conclusion: Animal hoarding is a complex condition that requires urgent attention. More research is necessary to develop effective strategies that can save community resources, improve animal and human welfare, and prevent recidivism.

Objectives: To summarize evidence-based pharmacological treatments and provide guidance on clinical interventions for adult patients with obsessive-compulsive disorder (OCD). Methods: The American Psychiatric Association (APA) guidelines for the treatment of OCD (2013) were updated with a systematic review assessing the efficacy of pharmacological treatments for adult OCD, comprising monotherapy with selective serotonin reuptake inhibitors (SSRIs), clomipramine, serotonin and norepinephrine reuptake inhibitors (SNRIs), and augmentation strategies with clomipramine, antipsychotics, and glutamate-modulating agents. We searched for the literature published from 2013-2020 in five databases, considering the design of the study, primary outcome measures, types of publication, and language. Selected articles had their quality assessed with validated tools. Treatment recommendations were classified according to levels of evidence developed by the American College of Cardiology and the American Heart Association (ACC/AHA). Results: We examined 57 new studies to update the 2013 APA guidelines. High-quality evidence supports SSRIs for first-line pharmacological treatment of OCD. Moreover, augmentation of SSRIs with antipsychotics (risperidone, aripiprazole) is the most evidence-based pharmacological intervention for SSRI-resistant OCD. Conclusion: SSRIs, in the highest recommended or tolerable doses for 8-12 weeks, remain the first-line treatment for adult OCD. Optimal augmentation strategies for SSRI-resistant OCD include low doses of risperidone or aripiprazole. Pharmacological treatments considered ineffective or potentially harmful, such as monotherapy with antipsychotics or augmentation with ketamine, lamotrigine, or N-acetylcysteine, have also been detailed.

Despite the long-held view that hoarding is a symptom of both obsessive-compulsive disorder and obsessive-compulsive personality disorder, increased evidence has emerged during the last 20 years suggesting that hoarding represents a distinct form of psychopathology. This study reflects the discussions on the nosological status of hoarding carried out by the WHO ICD-11 Working Group on the Classification of Obsessive-Compulsive and Related Disorders. The distinctiveness of hoarding is based on its having core symptoms that differ from those of other disorders, as well as distinctive neurobiological correlates and treatment responses. Furthermore, data showing the clinical utility, global applicability, and appropriateness of the concept of hoarding disorder outside specialty mental health settings suggest that this condition should be included in ICD-11. Finally, given the focus of ICD-11 on primary care and public health, the Working Group suggests that poor insight and severe domestic squalor may be considered as specifiers for hoarding disorder in ICD-11.

OBJETIVO: Este artigo tem por objetivo descrever as principais características clínicas e terapêuticas que possam predizer resposta ao tratamento em pacientes com transtorno de ansiedade social (TAS). MÉTODOS: Revisão sistemática de ensaios clínicos identificados através das bases de dados ISI, Medline, PsycInfo, Cochrane, LILACS, Current Controlled Trials e em referências bibliográficas de artigos previamente selecionados publicados em inglês até dezembro de 2010. As seguintes palavras-chave foram utilizadas em nossa busca bibliográfica: prediction/predictors e social anxiety disorder ou social phobia. RESULTADOS: Início precoce, maior gravidade da doença, comorbidade com outros transtornos de ansiedade (incluindo o transtorno de ansiedade generalizada e fobia simples) e alta expectativa sobre o papel do terapeuta emergiram como potenciais fatores de predição menor eficácia do tratamento do TAS. CONCLUSÕES: O conhecimento de uma variedade de características clínicas e de tratamento pode auxiliar os profissionais a preverem possíveis respostas às intervenções terapêuticas nos pacientes com TAS. No entanto, devido à diversidade de medidas utilizadas para avaliar a resposta, novos estudos com o objetivo de investigar aspectos relacionados à resistência ao tratamento do TAS devem ser realizados com métodos mais padronizados.

OBJECTIVE: This article aims to review the clinical features and therapeutic characteristics that may predict treatment response in patients with social anxiety disorder (SAD). METHODS: A systematic review of trials identified through databases of ISI, Medline, PsycInfo, Cochrane, LILACS, Current Controlled Trials, and in references of previously selected articles published in English up to December 2010. In our literature search, we used the words prediction/predictors and social anxiety disorder or social phobia. RESULTS: Early onset, greater disease severity, comorbidity with other anxiety disorders (including generalized anxiety disorder and simple phobia), and high expectations about the role of the therapist emerged as potential predictors of less effective treatment in SAD. CONCLUSIONS: Knowledge of various clinical and treatment features may help professionals to predict possible responses to therapeutic interventions in patients with SAD. However, given the diversity of measures used to assess response, further studies should be performed with standardized methods to investigate the aspects related to treatment resistance in SAD.

CONTEXTO: Enrubescimento, tremores e transpiração excessiva são fenômenos frequentemente observados na fobia social. OBJETIVOS: Descrever a resposta de um paciente com o tipo generalizado de fobia social e hiperidrose à terapia cognitivo-comportamental aliada à toxina botulínica. MÉTODO: Relato de caso único. RESULTADOS: O Sr. A, 20 anos, estudante universitário, procurou tratamento por apresentar sintomas compatíveis com os diagnósticos de fobia social e depressão. O Sr. A também apresentava diagnóstico de hiperidrose palmar, plantar e axilar. Tanto a fobia social quanto a hiperidrose tiveram seu início no começo da adolescência, com a primeira se iniciando quatro anos antes da segunda. A terapia cognitivo-comportamental levou à remissão da depressão, mas o tratamento efetivo da fobia social apenas foi possível após a terapia com a toxina botulínica. CONCLUSÃO: A toxina botulínica, um tratamento que bloqueia fenômenos autonômicos periféricos, também pode proporcionar alívio dos sintomas em pacientes com fobia social.

BACKGROUND: Blushing, trembling, and sweating are frequently seen in social phobia. OBJECTIVES: In this study, we aimed at describing the response of a patient with a generalized type of social phobia and hyperhydrosis to cognitive-behavioral therapy augmented by botulinum toxin. METHOD: Single case report. RESULTS: Mr. A, a 20 year-old university student, sought treatment in our unit for social phobia with comorbid depression. Mr. A also exhibited a diagnosis of palmar, plantar, and axilar hyperidrosis. He described that exposure to feared situations always lead to aggravation of sweating and other symptoms of heightened physiological arousal. Both social phobia and hyperhydrosis had their onset in early adolescence, with the former beginning four years before the latter. Cognitive-behavioral therapy led to aliviation of depression but effective treatment of social phobia was only possible after therapy with botulinum toxin. DISCUSSION: Botulinum toxin, a treatment that blocks peripheral autonomic symptoms, might also lead to improvement of social phobia.

CONTEXTO: Avaliações tradicionais de sintomas obsessivo-compulsivos, baseadas na introspecção, estão sujeitas a diversas variáveis, como os níveis de insight apresentados pelo paciente. OBJETIVOS: Neste estudo, nosso objetivo foi o de avaliar a consistência interna e as correlações clínicas de um teste que busca identificar a existência de um viés cognitivo implícito em pacientes com transtorno obsessivo-compulsivo (TOC). MÉTODOS: Quarenta pacientes com TOC realizaram o teste de associação implícita para o TOC (TAI-TOC) e responderam a três instrumentos de autoavaliação [Inventário de Ansiedade de Beck (BAI), Inventário de Depressão de Beck (BDI), Inventário de Obsessões e Compulsões - Revisado (OCI-R)]. RESULTADOS: O valor do alfa de Cronbach com itens de treino foi de 0,83 e sem o treino foi de 0,79. Não foram observadas correlações significativas entre os escores gerados pelo TAI-TOC e os instrumentos de autoavaliação, i.e., BDI, BAI e diferentes dimensões do OCI-R. CONCLUSÃO: Nossos achados apontam para uma elevada consistência interna do TAI-TOC. A ausência de correlações entre o TAI-TOC e diferentes dimensões do OCI-R sugere que medidas implícitas e explícitas de sintomas obsessivo-compulsivos podem formar constructos independentes. Estudos futuros, com maior número de pacientes, são necessários para confirmar essa hipótese.

BACKGROUND: Traditional assessments of obsessive-compulsive symptoms, based on patients' introspection, are subject to several factors, including the levels of insight presented by them. OBJECTIVES: In this study, our goal was to assess the internal consistency and clinical correlations of a test that seeks to identify the existence of an implicit cognitive bias in patients with obsessive-compulsive disorder (OCD). METHODS: 40 patients with OCD performed the implicit association test for OCD (IAT-OCD) and answered three instruments of self-assessment [Beck Anxiety Inventory (BAI), Inventory, Beck Depression Inventory (BDI), Obsessive-Compulsive Inventory-Revised (OCI-R)]. RESULTS: Cronbach's alpha with IAT-OCD training items was 0.83 and without them 0.79. There were no significant correlations between the IAT-OCD scores and the instruments of self-assessment, e.g., BDI, BAI and different dimensions of the OCI-R. DISCUSSION: Our findings are consistent with a high internal consistency of the IAT-OCD. The absence of correlations between the IAT-OCD and different dimensions of the OCI-R suggests that implicit and explicit measures of obsessive-compulsive symptoms may be independent constructs. Future studies, with greater number of patients, are needed to confirm this hypothesis.

OBJETIVO: Neste estudo, o objetivo foi relatar o caso de uma paciente com transtorno de estresse pós-traumático (TEPT) de início aparentemente tardio e os diferentes dilemas surgidos durante seu diagnóstico. MÉTODO: Relato de caso. RESULTADOS: Paciente feminina, de 34 anos, casada e do lar, apresentou TEPT 25 anos após o desabamento de sua residência durante uma enchente. O quadro surgiu após relatos na imprensa de eventos semelhantes associados ao soterramento de dezenas de vítimas em um município vizinho. CONCLUSÃO: Este caso sugere que pacientes podem desenvolver quadros semelhantes ao TEPT de início tardio após a reexposição a eventos previamente desprovidos de impacto emocional.

OBJECTIVE: In this study, our objective was to report a patient with an apparent diagnosis of delayed-onset posttraumatic stress disorder (PTSD) and the different dilemmas faced during the diagnostic process. METHOD: Case report. RESULTS: A female patient, aged 34, married, housewife, presented PTSD 25 years after the collapse of her home during a flooding. The condition emerged after press reports of similar events associated with the death of dozens of victims in a nearby town. CONCLUSION: Our case suggests that patients may develop conditions that bear resemblance to late-onset PTSD after re-exposure to events previously devoid of emotional impact.