Resumo Este artigo objetivou analisar recomendações para educação em saúde de gestantes e puérperas em tempos de pandemia de Covid-19. Trata-se de uma revisão integrativa que ocorreu no período setembro de 2021 a fevereiro de 2022, nas bases de dados MEDLINE via PubMed, Literatura Latino-Americana e do Caribe em Ciências da Saúde, Scientific Electronic Library Online e na Biblioteca Virtual em Saúde. Utilizou-se o software online Endnote Web para armazenar as referências obtidas na busca e retirar duplicações. A amostra final foi composta por 17 estudos. Após análise, os achados foram distribuídos em duas categorias: educação em saúde para assistência pré-natal de gestantes e educação em saúde para bem-estar físico e mental de gestantes e puérperas. O estudo mostrou que as recomendações para gestantes e puérperas, no cenário pandêmico, tem ênfase na educação em saúde associada a ferramentas tecnológicas durante todo o processo gravídico-puerperal, baseadas em informações e estratégias que favoreçam a promoção da saúde e a prevenção de agravos.

Abstract This article aimed to analyze recommendations for health education for pregnant and postpartum women in times of the Covid-19 pandemic. This is an integrative review that took place from September 2021 to February 2022, in the MEDLINE databases via PubMed, Latin American and Caribbean Health Sciences Literature, Scientific Electronic Library Online and the Virtual Health Library. The online software Endnote Web was used to store the references obtained in the search and to remove duplications. The final sample consisted of 17 studies. After analysis, the findings were divided into two categories: health education for prenatal care of pregnant women and health education for the physical and mental well-being of pregnant and postpartum women. The study showed that the recommendations for pregnant and puerperal women, in the pandemic scenario, emphasize health education associated with technological tools throughout the pregnancy-puerperal process, based on information and strategies that favor health promotion and disease prevention.

Abstract: Aim We investigated the ichthyofauna parasite component community across a gradient of anthropogenic pressures of the Guaraguaçu River, south Brazil, a Neotropical river of central importance for biodiversity conservation. Methods After fish sampling, all fish were identified, measured, weighed and eviscerated. The viscera and gills were inspected for parasite screening and subsequent identification. Parasite diversity estimators were calculated for the most abundant host species. Results A total of 159 host specimens from 12 species were examined, being 140 (88.05%) found to be infected with at least one parasite, including 14 new parasite occurrences. The most widely distributed parasite was the nematode Contracaecum sp., found in 8 host species. The highest mean infection intensity and mean abundance was observed for the monogenean Aphanoblastella mastigatus, infecting the Silver catfish Rhamdia quelen. The Shannon-Wiener, Jost and Simpson indexes were higher for the more abundant fishes, except for the Trahira Hoplias malabaricus. Most host species harbored parasites in poorly aggregated distribution, according to the discrepancy index. The Berger-Parker index showed monogenean dominance in all hosts except for H. malabaricus. We found little evidence for parasite infracommunity changes across the gradient of the river. Conclusions We described the infection patterns in an important Neotropical river. The new parasite occurrences highlight the contribution of our study. Fish-parasite interactions changed throughout the river stretches, and we argue that it does not necessarily means changes in diversity and abundance of parasite within species, but the rearrange of interactions. Moreover, it seems that parasites are more abundant in most impacted sites, another reason to continue the monitoring. Abstract River Brazil conservation sampling identified measured eviscerated identification 15 1 examined 88.05% 8805 88 05 (88.05% sp sp. mastigatus quelen ShannonWiener, ShannonWiener Shannon Wiener, Wiener Shannon-Wiener fishes malabaricus distribution BergerParker Berger Parker H study Fishparasite Fish stretches Moreover sites monitoring 88.05 880 0 (88.05 88.0 (88.0 88. (88. (88 (8 (

Resumo: Objetivo A comunidade componente de parasitas da ictiofauna foi investigada ao longo de um gradiente de pressões antropogênicas no Rio Guaraguaçu, sul do Brasil, um rio Neotropical com grande importância para a conservação da biodiversidade. Métodos Após a coleta, todos os peixes foram identificados, medidos, pesados e eviscerados. As vísceras e brânquias foram inspecionadas para coleta e subsequente identificação de parasitas. Estimadores de diversidade de parasitas foram calculados para as espécies de hospedeiros mais abundantes. Resultados Um total de 159 espécimes de hospedeiros de 12 espécies foram examinados, sendo 140 (88,05%) infectados com pelo menos um parasita, incluindo 14 novas ocorrências de parasitas. O parasita mais amplamente distribuído foi o nematoide Contracaecum sp., encontrado em 8 espécies de hospedeiros. As maiores intensidades de infecção e abundância foram observadas para o monogenético Aphanoblastella mastigatus, infectando o Jundiá Rhamdia quelen. Os índices de Shannon-Wiener, Jost e Simpson foram maiores para os peixes mais abundantes, exceto para a Traíra Hoplias malabaricus. A maioria das espécies de hospedeiros abrigava parasitas com distribuição pouco agregada, de acordo com o índice de discrepância. O índice de Berger-Parker mostrou a dominância de monogenéticos em todos os hospedeiros, exceto H. malabaricus. Encontramos poucas evidências de mudanças nas infracomunidades de parasitas ao longo do gradiente do rio. Conclusões Descrevemos os padrões de infecção em um importante rio Neotropical. As novas ocorrências de parasitas destacam a importância de nosso estudo. Interações entre parasitos e peixes mudaram ao longo dos setores do rio, e isso não necessariamente resulta em mudanças na diversidade e abundância de parasitos dentro de cada espécie, mas um rearranjo das interações. Além disso, parece que os parasitas são mais abundantes na maioria dos locais impactados, o que é mais uma razão para continuar o monitoramento. Resumo Guaraguaçu Brasil biodiversidade identificados medidos eviscerados 15 1 examinados 88,05% 8805 88 05 (88,05% sp sp. mastigatus quelen ShannonWiener, ShannonWiener Shannon Wiener, Wiener Shannon-Wiener malabaricus agregada discrepância BergerParker Berger Parker H estudo espécie interações disso impactados monitoramento 88,05 880 0 (88,05 88,0 (88,0 88, (88, (88 (8 (

Abstract This article aimed to analyze recommendations for health education for pregnant and postpartum women in times of the Covid-19 pandemic. This is an integrative review that took place from September 2021 to February 2022, in the MEDLINE databases via PubMed, Latin American and Caribbean Health Sciences Literature, Scientific Electronic Library Online and the Virtual Health Library. The online software Endnote Web was used to store the references obtained in the search and to remove duplications. The final sample consisted of 17 studies. After analysis, the findings were divided into two categories: health education for prenatal care of pregnant women and health education for the physical and mental well-being of pregnant and postpartum women. The study showed that the recommendations for pregnant and puerperal women, in the pandemic scenario, emphasize health education associated with technological tools throughout the pregnancy-puerperal process, based on information and strategies that favor health promotion and disease prevention. Covid19 Covid 19 Covid-1 202 2022 PubMed Literature duplications 1 studies analysis categories wellbeing well being scenario pregnancypuerperal pregnancy process prevention Covid1 Covid- 20 2

Resumo Este artigo objetivou analisar recomendações para educação em saúde de gestantes e puérperas em tempos de pandemia de Covid-19. Trata-se de uma revisão integrativa que ocorreu no período setembro de 2021 a fevereiro de 2022, nas bases de dados MEDLINE via PubMed, Literatura Latino-Americana e do Caribe em Ciências da Saúde, Scientific Electronic Library Online e na Biblioteca Virtual em Saúde. Utilizou-se o software online Endnote Web para armazenar as referências obtidas na busca e retirar duplicações. A amostra final foi composta por 17 estudos. Após análise, os achados foram distribuídos em duas categorias: educação em saúde para assistência pré-natal de gestantes e educação em saúde para bem-estar físico e mental de gestantes e puérperas. O estudo mostrou que as recomendações para gestantes e puérperas, no cenário pandêmico, tem ênfase na educação em saúde associada a ferramentas tecnológicas durante todo o processo gravídico-puerperal, baseadas em informações e estratégias que favoreçam a promoção da saúde e a prevenção de agravos. Covid19. Covid19 Covid 19. 19 Covid-19 Tratase Trata se 202 2022 PubMed LatinoAmericana Latino Americana Saúde Utilizouse Utilizou duplicações 1 estudos análise categorias prénatal pré natal bemestar bem estar pandêmico gravídicopuerperal, gravídicopuerperal gravídico puerperal, puerperal gravídico-puerperal agravos Covid1 Covid-1 20 Covid- 2

Abstract The demand for low-cost and time-efficient biomonitoring and ecological assessment strategies has increased due to threats to biodiversity. We evaluated the ability of surrogates (genera and biovolume classes) to access information provided by diatom species. Moreover, we investigated whether the relative importance of spatial and environment on diatom communities identified at the genus or classified at biovolume classes reflects the ecological responses at the species. We used biotic, environmental, and spatial data from Pampa streams. We employed Procrustes analysis to detect whether the spatial variation of communities at the species level was represented by the surrogates and variation partitioning to evaluate the relative importance of spatial and environment. We found high congruence between the surrogates and diatom species communities. Furthermore, whilst both spatial and environment were important to explain species composition, only the environment was important for both surrogates. We suggest that the use of genus-level determinations can provide information about the environmental relationships of species, whereas biovolume classes may be useful to detect changes in diatom communities. These results are a first step to seek for strategies aiming to simplify biological monitoring and assessments at pampean streams, especially considering the demand for the identification of organisms at the species. lowcost low cost timeefficient time efficient biodiversity genera Moreover biotic streams Furthermore composition genuslevel

Abstract Objective: This meta-analysis of randomized controlled trials (RCTs) aimed to update evidence on the effectiveness and safety of laser therapy for treating genitourinary syndrome of menopause (GSM). Data sources: Manuscripts published until May 2023 were systematically searched in PubMed; Embase; Scopus; Web of Science; CENTRAL; CINAHL; and clinical trial databases (www.trialscentral.org, www.controlled-trials.com, and clinicaltrials.gov), with no language and year of publication restriction. Studies selection: RCTs with women diagnosed with GSM, and the intervention was vaginal laser therapy (CO2-laser or Er: YAG-laser) comparing with placebo (sham therapy), no treatment or vaginal estrogen therapy. Data collection: Two authors evaluated the publications for inclusion based on the title and abstract, followed by reviewing the relevant full-text articles. Disagreements during the review process were addressed by consensus, with the involvement of a third author. Data synthesis: Twelve RCTs, representing a total of 5147 participants, were included in this review. Vaginal health index (VHI) significantly improved in the carbon dioxide laser (CO2-laser) therapy group (MD=2.21; 95% CI=1.25 to 3.16), while dyspareunia (MD=−0.85; 95% CI=−1.59 to −0.10), dryness (MD=−0.62; 95% CI=−1.12 to −0.12) and burning (MD= −0.64; 95% CI=−1.28 to −0.01) decreased. No serious adverse effects were reported. Conclusion: CO2-laser increases VHI score and decreases dyspareunia, dryness and burning, especially when compared to sham-laser. However, the certainty of the evidence is low, thus preventing the recommendation of laser therapy for GSM management. Objective metaanalysis meta analysis (RCTs GSM. . (GSM) sources 202 PubMed Embase Scopus Science CENTRAL CINAHL www.trialscentral.org, wwwtrialscentralorg www trialscentral org (www.trialscentral.org www.controlledtrials.com, wwwcontrolledtrialscom www.controlled trials.com, com www.controlled-trials.com clinicaltrials.gov, clinicaltrialsgov clinicaltrials.gov , clinicaltrials gov clinicaltrials.gov) restriction selection CO2laser COlaser CO2 CO Er YAGlaser YAG YAG-laser sham therapy, therapy) collection abstract fulltext full text articles consensus author synthesis 514 participants (VHI MD=2.21 MD221 MD 2 21 (MD=2.21 95 CI125 CI 1 25 CI=1.2 3.16, 316 3.16 3 16 3.16) MD=−0.85 MD085 0 85 (MD=−0.85 CI159 59 CI=−1.5 −0.10, 010 −0.10 10 −0.10) MD=−0.62 MD062 62 (MD=−0.62 CI112 12 CI=−1.1 −0.12 012 MD= (MD −0.64 064 64 CI128 28 CI=−1.2 −0.01 001 01 decreased reported Conclusion shamlaser. shamlaser laser. sham-laser However low management (GSM 20 www.trialscentral.org controlledtrials www.controlledtrials.com wwwcontrolled trialscom trials.com 51 MD=2.2 MD22 (MD=2.2 9 CI12 CI=1. 31 3.1 MD=−0.8 MD08 8 (MD=−0.8 CI15 5 CI=−1. −0.1 MD=−0.6 MD06 6 (MD=−0.6 CI11 −0.6 06 −0.0 00 MD=2. MD2 (MD=2. CI1 CI=1 3. MD=−0. MD0 (MD=−0. CI=−1 −0. MD=2 (MD=2 CI= MD=−0 (MD=−0 CI=− −0 MD=− (MD=− −

Resumen Los procesos administrativos de reconocimiento de tierras indígenas (TI) en Brasil pueden tardar décadas en llegar a su fin. Los pueblos indígenas que viven en TI cuyo proceso de reconocimiento aún no se finalizó son más vulnerables a una serie de violaciones de derechos, lo que hace urgente su conclusión. Este artículo pretende dar respuesta a la siguiente pregunta: ¿por qué algunos procesos de demarcación demoran más que otros? En primer lugar, enumeramos cinco condiciones encontradas en la literatura sobre la demarcación de tierras indígenas que pueden atrasar dichos procesos. A continuación, aplicamos el método de análisis cualitativo comparativo (QCA), en su modo crisp set, a un conjunto de cuarenta casos de demarcaciones de TI. Presentamos dos conclusiones: que la presencia de intereses económicos es una condición importante para explicar el largo tiempo de algunos procesos de demarcación, pero no es necesaria ni suficiente, y que la conjunción de este factor con la judicialización del proceso de demarcación explica la mayoría de los casos de demarcaciones de larga duración. (TI fin derechos conclusión pregunta por otros lugar continuación QCA, QCA , (QCA) set conclusiones suficiente duración (QCA

Abstract The administrative processes of recognizing Indigenous Lands (ILs) in Brazil can take decades to complete. Indigenous peoples who live in unrecognized ILs are more vulnerable to a series of rights violations, which makes the completion of demarcation processes urgent. This article aims to answer the following question: why do some demarcation processes take longer than others? We listed five conditions found in the literature on the demarcation of indigenous lands that can delay them. Next, we applied the qualitative comparative analysis (QCA) method in its crisp set mode to 40 cases of IL demarcation. We present two conclusions: the presence of economic interests is an important condition to explain the long duration of some demarcation processes, but it is neither necessary nor sufficient, and the conjunction of this factor with the judicialization of the demarcation process explains most cases of long-term demarcations. (ILs complete violations urgent question others them Next QCA (QCA 4 conclusions sufficient longterm term demarcations

Resumo Os processos administrativos de reconhecimento de terras indígenas (TIs) no Brasil podem levar décadas para chegar a termo. Povos indígenas que habitam em TIs não reconhecidas em caráter final são mais vulneráveis a uma série de violações de direitos, o que torna premente sua conclusão. O presente artigo pretende oferecer uma resposta à seguinte pergunta: por que alguns processos demarcatórios demoram mais que outros? Primeiramente, arrolamos cinco condições constantes da literatura sobre demarcação de terras indígenas que podem postergá-las. Na sequência, aplicamos o método qualitative comparative analysis (QCA), em sua modalidade crisp set, a um conjunto de quarenta casos de demarcações de TIs. Apresentamos duas conclusões: que a presença de interesses econômicos é uma condição importante para explicar o longo tempo de alguns processos demarcatórios, mas não é necessária nem suficiente, e que a conjunção desse fator com a judicialização do processo demarcatório explica a maioria dos casos de demarcações de longa duração. (TIs termo direitos conclusão pergunta outros Primeiramente postergálas. postergálas postergá las. las postergá-las sequência QCA, QCA , (QCA) set conclusões suficiente duração (QCA

Abstract Objective To assess the efficacy, safety, and acceptability of misoprostol in the treatment of incomplete miscarriage. Data sources The PubMed, Scopus, Embase, Web of Science, Cochrane Library, and Clinical Trials databases (clinicaltrials.gov) were searched for the relevant articles, and search strategies were developed using a combination of thematic Medical Subject Headings terms and text words. The last search was conducted on July 4, 2022. No language restrictions were applied. Selection of studies Randomized clinical trials with patients of gestational age up to 6/7 weeks with a diagnosis of incomplete abortion and who were managed with at least 1 of the 3 types of treatment studied were included. A total of 8,087 studies were screened. Data collection Data were synthesized using the statistical package Review Manager V.5.1 (The Cochrane Collaboration, Oxford, United Kingdom). For dichotomous outcomes, the odds ratio (OR) and 95% confidence interval (CI) were derived for each study. Heterogeneity between the trial results was evaluated using the standard test, I2 statistic. Data synthesis When comparing misoprostol with medical vacuum aspiration (MVA), the rate of complete abortion was higher in the MVA group (OR = 0.16; 95%CI = 0.07–0.36). Hemorrhage or heavy bleeding was more common in the misoprostol group (OR = 3.00; 95%CI = 1.96–4.59), but pain after treatment was more common in patients treated with MVA (OR = 0.65; 95%CI = 0.52–0.80). No statistically significant differences were observed in the general acceptability of the treatments. Conclusion Misoprostol has been determined as a safe option with good acceptance by patients. efficacy safety miscarriage PubMed Scopus Embase Science Library clinicaltrials.gov clinicaltrialsgov clinicaltrials gov (clinicaltrials.gov articles words 4 2022 applied 67 6 7 6/ included 8087 8 087 8,08 screened V51 V 5 V.5. Collaboration Oxford Kingdom. Kingdom . Kingdom) outcomes OR 95 CI (CI study test I statistic MVA, , (MVA) 0.16 016 0 16 95CI 0.07–0.36. 007036 0.07–0.36 07 36 0.07–0.36) 3.00 300 00 1.96–4.59, 196459 1.96–4.59 96 59 1.96–4.59) 0.65 065 65 0.52–0.80. 052080 0.52–0.80 52 80 0.52–0.80) treatments 202 808 08 8,0 V5 V.5 9 (MVA 0.1 01 00703 0.07–0.3 3.0 30 19645 1.96–4.5 0.6 06 05208 0.52–0.8 20 8, V. 0. 0070 0.07–0. 3. 1964 1.96–4. 0520 0.52–0. 2 007 0.07–0 196 1.96–4 052 0.52–0 0.07– 19 1.96– 05 0.52– 0.07 1.96 0.52 0.0 1.9 0.5 1.

Resumo Objetivo Avaliar a eficácia, segurança e aceitabilidade do misoprostol no tratamento do aborto incompleto. Fontes de dados Os bancos de dados PubMed, Scopus, Embase, Web of Science, Cochrane Library e bancos de dados de Ensaios Clínicos (clinicaltrials.gov) foram pesquisados para os artigos relevantes, e estratégias de busca foram desenvolvidas usando uma combinação de termos temáticos de Medical Subject Headings e palavras de texto. A última pesquisa foi realizada em 4 de julho de 2022. Nenhuma restrição de idioma foi aplicada. Seleção dos estudos Foram incluídos ensaios clínicos randomizados com pacientes com idade gestacional até 6/7 semanas com diagnóstico de aborto incompleto e que foram manejadas com pelo menos um dos três tipos de tratamento estudados. Um total de 8.087 estudos foram selecionados. Coleta de dados Os dados foram sintetizados usando o pacote estatístico Review Manager V.5.1 (The Cochrane Collaboration, Oxford, United Kingdom). Para resultados dicotômicos, o odds ratio (OR, na sigla em inglês) e o intervalo de confiança (IC) de 95% foram derivados para cada estudo. A heterogeneidade entre os resultados do ensaio foi avaliada usando o teste padrão, estatística I2. Síntese dos dados Ao comparar misoprostol com aspiração a vácuo médico (MVA, na sigla em inglês), a taxa de aborto completo foi maior no grupo MVA (OR = 0,16; IC95% = 0,07–0,36). Hemorragia ou sangramento intenso foi mais comum no grupo do misoprostol (OR = 3,00; 95%CI = 1,96–4,59), mas a dor após o tratamento foi mais comum em pacientes tratados com MVA (OR = 0,65; 95%CI = 0,52–0,80). Não foram observadas diferenças estatisticamente significativas na aceitabilidade geral dos tratamentos. Conclusão O misoprostol tem se mostrado uma opção segura e com boa aceitação pelos pacientes. eficácia PubMed Scopus Embase Science clinicaltrials.gov clinicaltrialsgov clinicaltrials gov (clinicaltrials.gov relevantes texto 2022 aplicada 67 6 7 6/ estudados 8087 8 087 8.08 selecionados V51 V 5 1 V.5. The Collaboration Oxford Kingdom. Kingdom . Kingdom) dicotômicos OR, OR inglês IC (IC 95 estudo padrão I2 I MVA, (MVA inglês, , 0,16 016 0 16 IC95 0,07–0,36. 007036 0,07–0,36 07 36 0,07–0,36) 3,00 300 3 00 95CI CI 1,96–4,59, 196459 1,96–4,59 96 59 1,96–4,59) 0,65 065 65 0,52–0,80. 052080 0,52–0,80 52 80 0,52–0,80) tratamentos 202 808 08 8.0 V5 V.5 9 0,1 01 IC9 00703 0,07–0,3 3,0 30 19645 1,96–4,5 0,6 06 05208 0,52–0,8 20 8. V. 0, 0070 0,07–0, 3, 1964 1,96–4, 0520 0,52–0, 2 007 0,07–0 196 1,96–4 052 0,52–0 0,07– 19 1,96– 05 0,52– 0,07 1,96 0,52 0,0 1,9 0,5 1,

Text mining and related analytics emerge as a technological approach to support human activities in extracting useful knowledge through texts in several formats. From a managerial point of view, it can help organizations in planning and decision-making processes, providing information that was not previously evident through textual materials produced internally or even externally. In this context, within the public/governmental scope, public security agencies are great beneficiaries of the tools associated with text mining, in several aspects, from applications in the criminal area to the collection of people's opinions and sentiments about the actions taken to promote their welfare. This article reports details of a systematic literature review focused on identifying the main areas of text mining application in public security, the most recurrent technological tools, and future research directions. The searches covered four major article bases (Scopus, Web of Science, IEEE Xplore, and ACM Digital Library), selecting 194 materials published between 2014 and the first half of 2021, among journals, conferences, and book chapters. There were several findings concerning the targets of the literature review, as presented in the results of this article.

SUMMARY OBJECTIVE: The objective of this study was to determine adverse maternal and perinatal outcomes in pregnant women with hypertensive disorders of pregnancy. METHODS: An analytical cross-sectional study was conducted on women admitted with hypertensive disorders of pregnancies to a university maternity hospital from August 2020 to August 2022. Data were collected using a pretested structured questionnaire. Variables associated with adverse maternal and perinatal outcomes were compared using multivariable binomial regression. RESULTS: Of 501 women with pregnancies, 2, 35, 14, and 49% had eclampsia, preeclampsia, chronic hypertension, and gestational hypertension, respectively. Women with preeclampsia/eclampsia had significantly higher risks of cesarean section (79.4 vs. 65%; adjusted RR, 2,139; 95%CI, 1,386–3,302; p=0.001) and preterm delivery at <34 weeks’ gestation (20.5 vs. 6%; adjusted RR, 2.5; 95%CI, 1.19–5.25; p=0.01) than those of women with chronic/gestational hypertension. Risks of prolonged maternal hospitalization (43.9 vs. 27.1%), neonatal intensive care unit admission (30.7 vs. 19.8%), and perinatal mortality (23.5 vs. 11.2%) were higher among women with preeclampsia/eclampsia. CONCLUSIONS: Women with preeclampsia/eclampsia had a higher risk of adverse maternal and neonatal outcomes than those with chronic or gestational hypertension. This major maternity care center requires strategies for preventing and managing preeclampsia/eclampsia to improve pregnancy outcomes. OBJECTIVE METHODS crosssectional cross sectional 202 2022 questionnaire regression RESULTS 50 2 35 14 49 eclampsia preeclampsia hypertension respectively preeclampsiaeclampsia 79.4 794 79 4 (79. vs 65% 65 RR 2,139 2139 139 95CI CI 95 95%CI 1,386–3,302 13863302 1 386 3 302 p=0.001 p0001 p 0 001 34 <3 weeks 20.5 205 20 5 (20. 6% 6 2.5 25 1.19–5.25 119525 19 p=0.01 p001 01 chronicgestational 43.9 439 43 9 (43. 27.1%, 271 27.1% , 27 27.1%) 30.7 307 30 7 (30. 19.8%, 198 19.8% 8 19.8%) 23.5 235 23 (23. 11.2% 112 11 CONCLUSIONS 79. (79 2,13 213 13 1,386–3,30 1386330 38 p=0.00 p000 00 < 20. (20 2. 1.19–5.2 11952 p=0.0 p00 43. (43 27.1 30. (30 19.8 23. (23 11.2 (7 2,1 21 1,386–3,3 138633 (2 1.19–5. 1195 p=0. p0 (4 27. (3 19. 11. ( 1,386–3, 13863 1.19–5 119 p=0 1,386–3 1386 1.19– p= 1,386– 138 1.19 1,386 1.1 1,38 1. 1,3 1,

ABSTRACT This paper presents a broad overview of main contributions related to the FITradeoff (Flexible and Interactive Tradeoff) method. FITradeoff is a multicriteria method developed within the scope of the Multiattribute Value Theory (MAVT), considering partial information from the decision maker (DM) in the preference modelling process. Over the last few years, several methodological developments on this method have been published in the literature, as well as practical applications to a wide range of multicriteria decision problems. The most recent methodological advances are related to preference modelling process, which now integrate the two paradigms of elicitation by decomposition and holistic evaluation. Furthermore, contributions from behavioral studies, some of them including decision neuroscience, have enhanced the DSS free available for FITradeoff. In this paper, all previously developed works related to the FITradeoff method are approached, considering both methodological developments and practical applications. A summary on the different modeling approaches for solving different decision problematics (choice, ranking, sorting and portfolio) with FITradeoff is presented. The recently proposed combination of preference modeling paradigms - elicitation by decomposition and holistic evaluation - within the FITradeoff decision process is explained, as well its potential advantages for the elicitation process. Moreover, a brief review on the practical applications of the method in different contexts is presented. In addition, this work also brings a summary on the results of behavioral experiments conducted using neuroscience tools with the FITradeoff method, as well the methodological insights resulted from them, and future perspectives of potential research topics related to the FITradeoff method. Flexible Tradeoff MAVT, MAVT , (MAVT) DM (DM years literature problems Furthermore studies approached choice, choice (choice ranking portfolio presented explained Moreover addition (MAVT

ABSTRACT This article aims to present a Multicriteria Decision Aiding (MCDA) model for assessing risk management maturity. Therefore, it is proposed to use a Maturity Model (MM) for risk management aligned with the ELECTRE TRI method. The ELECTRE TRI was chosen as the sorting method because it has a strong axiomatic structure based on the relationship of concordance and discordance between the alternative and the profile that delimits each of its classes. To test the proposal, a case study was carried out on a real company in the construction industry. For the development of the risk management maturity assessment model, a questionnaire was applied to collect data related to risk management practices in the organization. After collection, the data were used for modeling in a Decision Support System to apply the ELECTRE TRI, which managed to classify and identify the organization’s risk management maturity at level 3 (managed). MCDA (MCDA Therefore MM (MM classes proposal industry organization collection organizations s managed. . (managed) (managed

ABSTRACT Multiple sclerosis (MS) is a chronic and inflammatory autoimmune disease that affects the central nervous system (CNS). Dysfunction of body balance is also a common symptom and may be related to neurological injuries resulting from this disease. The aim of this study was to characterize the neurological and vestibular findings of three clinical cases diagnosed with MS. Data on the neurological evaluation and the magnetic resonance imaging of the skull were collected from the medical records. The patients responded to an initial interview and underwent clinical assessment of body balance and Video Head Impulse Test (vHIT). Vestibular symptoms and alterations were observed in at least one of the clinical tests of body balance and cerebellar function. In vHIT, changes were obtained in oculomotor tests, such as the presence of semi-spontaneous nystagmus and in parameters of the saccade test, and reduced gain in one or more vertical channels. Lesions were found on MRI of the skull in central areas that process vestibular information, such as the cerebellum and brainstem. The association of these findings suggests the presence of central vestibular dysfunction, compatible with the lesions detected in imaging exams. MS (MS CNS. CNS . (CNS) records vHIT. vHIT (vHIT) function semispontaneous semi spontaneous test channels information brainstem dysfunction exams (CNS (vHIT

RESUMO A Esclerose Múltipla (EM) é uma doença autoimune crônica e inflamatória que afeta o sistema nervoso central (SNC). A disfunção do equilíbrio corporal também é um sintoma comum e pode estar relacionada às lesões neurológicas decorrentes desta doença. O objetivo deste estudo foi caracterizar os achados neurológicos e vestibulares de três casos clínicos com diagnóstico de EM. Dados sobre a avaliação neurológica e do exame de ressonância magnética de crânio foram coletados dos prontuários. Os pacientes responderam a uma entrevista inicial e foram submetidos à avaliação clínica do equilíbrio corporal e ao Video Head Impulse Test (vHIT). Observou-se presença de sintomas vestibulares e alterações em pelo menos uma das provas clínicas do equilíbrio corporal e função cerebelar. No vHIT, obteve-se alterações em testes oculomotores, como presença de nistagmo semi-espontâneo e em parâmetros do teste sacádico, e ganho reduzido em um ou mais canais verticais. Foram verificadas lesões, na ressonância magnética de crânio, em áreas centrais que processam as informações vestibulares, como cerebelo e tronco encefálico. A associação destes achados sugere a presença de disfunção vestibular central, compatível com as lesões detectadas nos exames de imagem. EM (EM SNC. SNC . (SNC) prontuários vHIT. vHIT (vHIT) Observouse Observou se cerebelar obtevese obteve oculomotores semiespontâneo semi espontâneo sacádico verticais encefálico imagem (SNC (vHIT

Abstract Objective To evaluate the efficacy of the hormonal and nonhormonal approaches to symptoms of sexual dysfunction and vaginal atrophy in postmenopausal women. Data Sources We conducted a search on the PubMed, Embase, Scopus, Web of Science, SciELO, the Cochrane Central Register of Controlled Trials (CENTRAL), and Cumulative Index to Nursing and Allied Health Literature (CINAHL) databases, as well as on clinical trial databases. We analyzed studies published between 1996 and May 30, 2020. No language restrictions were applied. Selection of Studies We selected randomized clinical trials that evaluated the treatment of sexual dysfunction in postmenopausal women. Data Collection Three authors (ACAS, APFC, and JL) reviewed each article based on its title and abstract. Relevant data were subsequently taken from the full-text article. Any discrepancies during the review were resolved by consensus between all the listed authors. Data Synthesis A total of 55 studies were included in the systematic review. The approaches tested to treat sexual dysfunction were as follows: lubricants and moisturizers (18 studies); phytoestrogens (14 studies); dehydroepiandrosterone (DHEA; 8 studies); ospemifene (5 studies); vaginal testosterone (4 studies); pelvic floor muscle exercises (2 studies); oxytocin (2 studies); vaginal CO2 laser (2 studies); lidocaine (1 study); and vitamin E vaginal suppository (1 study). Conclusion We identified literature that lacks coherence in terms of the proposed treatments and selected outcome measures. Despite the great diversity in treatment modalities and outcome measures, the present systematic review can shed light on potential targets for the treatment, which is deemed necessary for sexual dysfunction, assuming that most randomized trials were evaluated with a low risk of bias according to the Cochrane Collaboration risk of bias tool. The present review is registered with the International Prospective Register of Systematic Reviews (PROSPERO; CRD42018100488). women PubMed Embase Scopus Science SciELO CENTRAL, CENTRAL , (CENTRAL) CINAHL (CINAHL databases 199 30 2020 applied ACAS, ACAS (ACAS APFC JL abstract fulltext full text 5 follows 18 studies) 14 DHEA (DHEA ( 4 2 CO 1 study study) study. . measures tool PROSPERO (PROSPERO CRD42018100488. CRD42018100488 CRD CRD42018100488) (CENTRAL 19 3 202 CRD4201810048 20 CRD420181004 CRD42018100 CRD4201810 CRD420181 CRD42018 CRD4201 CRD420 CRD42 CRD4

Resumo Objetivo Avaliar a eficácia das abordagens hormonais e não hormonais para os sintomas de disfunção sexual e atrofia vaginal em mulheres na pós-menopausa. Fontes de Dados Pesquisamos as bases de dados PubMed, Embase, Scopus, Web of Science, SciELO, Cochrane Central Register of Controlled Trials (CENTRAL), e Cumulative Index to Nursing and Allied Health Literature (CINAHL), assim como bancos de dados de ensaios clínicos. Foram analisados estudos publicados entre 1996 e 30 de maio de 2020. Nenhuma restrição de idioma foi aplicada. Seleção dos Estudos Foram selecionados ensaios clínicos randomizados que avaliavam o tratamento das disfunções sexuais em mulheres na pós-menopausa. Coleta de Dados Três autores (ACAS, APFC e JL), revisaram cada artigo com base em seu título e resumo. Os dados relevantes foram posteriormente retirados do texto completo do artigo. Quaisquer discrepâncias durante a revisão foram resolvidas por consenso entre todos os autores listados. Síntese dos Dados Ao todo, 55 estudos foram incluídos na revisão sistemática. As abordagens testadas para tratar a disfunção sexual foram: lubrificantes e hidratantes (18 estudos); fitoestrogênios (14 estudos); deidroepiandrosterona (DHEA; 8 estudos); ospemifeno (5 estudos); testosterona vaginal (4 estudos); exercícios para os músculos do assoalho pélvico (2 estudos); oxitocina (2 estudos);laser de CO2 vaginal (2 estudos); lidocaína (1 estudo), e vitamina E vaginal (1 estudo). Conclusão Identificou-se falta de coerência na literatura quanto aos tratamentos propostos e medidas de resultados selecionadas. Apesar da grande diversidade de modalidades de tratamento e medidas de resultados, esta revisão sistemática pode lançar luz sobre alvos potenciais para o tratamento, que é considerado necessário para a disfunção sexual, assumindo que a maioria dos estudos randomizados foi avaliada com baixo risco de viés de acordo com a ferramenta de avaliação de risco de viés de Cochrane Collaboration. Esta revisão tem cadastro no International Prospective Register of Systematic Reviews (PROSPERO; CRD42018100488). pósmenopausa. pósmenopausa pós menopausa. menopausa pós-menopausa PubMed Embase Scopus Science SciELO CENTRAL, CENTRAL , (CENTRAL) CINAHL, CINAHL (CINAHL) 199 3 2020 aplicada ACAS, ACAS (ACAS JL, JL JL) resumo listados todo 5 18 estudos) 14 DHEA (DHEA ( 4 2 estudoslaser laser CO 1 estudo, estudo estudo) estudo. . Identificouse Identificou se selecionadas Collaboration PROSPERO (PROSPERO CRD42018100488. CRD42018100488 CRD CRD42018100488) (CENTRAL (CINAHL 19 202 CRD4201810048 20 CRD420181004 CRD42018100 CRD4201810 CRD420181 CRD42018 CRD4201 CRD420 CRD42 CRD4

Resumo O interesse pela produção de Nanocristais de Celulose (NCCs) tem surgido pela procura de novos materiais. Os NCCs apresentam bom desempenho em compósitos poliméricos, por suas dimensões manométricas e sua rigidez. Sua produção impacta positivamente por seu baixo consumo energético e porque seus precursores podem ser qualquer biomassa lignocelulósica, diferente da madeira. A rota de extração convencional dos NCCs é a hidrólise ácida, usando ácido sulfúrico, ácido clorídrico ou uma mistura entre eles. Recentemente, tem-se registrado métodos alternativos de extração, que despertam o interesse para seu estudo por serem ambientalmente amigáveis e eficientes. Um deles destaca o uso de uma solução de persulfatos inorgânicos em uma única etapa de processo, sem prétratamento. Assim, os NCCs são extraídos diretamente sem a remoção prévia da lignina e da hemicelulose. A vantagem é o menor consumo de água, solventes e energia. Por outro lado, a comercialização da polpa de açaí desde a várzea amazônica tem crescido a um ritmo acelerado no mercado interno e externo, pelas propriedades, energéticas e nutricionais da fruta. Consequentemente, a geração de biomassa residual tem-se extrapolado, e as políticas sobre aproveitamento são ainda tímidas, resultando no despejo e descarte aleatório destes resíduos processados e em problemas ambientais. Este artigo apresenta um estado-da-arte sobre os desenvolvimentos em extração de NCCs da biomassa lignocelulósica pela oxidação com Persulfato de Amônio, destacando-se a utilização da biomassa do açaí.

Resumen El interés por la producción de Nanocristales de Celulosa (NCCs) ha surgido de la búsqueda por nuevos materiales. Los NCCs presentan buen desempeño en compuestos poliméricos por sus dimensiones nanométricas y su alta rigidez. Su producción impacta positivamente pues se requiere bajo consumo energético y, su fuente de extracción, puede ser cualquier biomasa lignocelulósica diferente de la madera. La ruta de extracción convencional de los NCCs es la hidrólisis ácida usando ácido sulfúrico o ácido clorhídrico o una mezcla entre ellos. Recientemente, se han registrado métodos alternativos de extracción, que han despertado interés en su estudio por ser ambientalmente amigables y eficientes. Uno de ellos destaca el uso persulfatos inorgánicos en una sola etapa de proceso, sin pretratamiento. Así, los NCCs son extraídos directamente sin la remoción previa de la lignina y de la hemicelulosa. La ventaja es el menor consumo de agua, solventes y energía. Por otro lado, la comercialización de la pulpa de açaí, desde la Amazonia ha crecido a un ritmo acelerado en el mercado interno y externo, lo cual se debe a las propiedades antioxidantes, energéticas y nutricionales de la fruta. Consecuentemente, la generación de la biomasa residual se ha extrapolado, y las políticas sobre aprovechamiento son todavía modestas, resultando en disposición y descartes aleatorios de los residuos procesados y en problemas ambientales. Este artículo presenta una revisión sobre los desarrollos en extracción de NCCs de la biomasa lignocelulosica por el método de oxidación con Persultafo de Amonio, destacándose la utilización de la biomasa del açaí.

Abstract The growing interest in the production of Cellulose Nanocrystals (CNCs) is due to the search for new materials. CNCs have shown good performance in polymeric composites because of their nanometric dimensions and strength. CNCs production have had a positive impact because of its low energy consumption, also any lignocellulosic biomass, different from wood can be used. The conventional extraction method of CNCs is the acid hydrolysis using sulfuric acid, hydrochloric acid or a mixture between them. Recently, alternative methods of extraction have aroused interest as they are eco-friendly and efficient. One of them highlights the use of inorganic persulfates solutions in a single process stage, where no pretreatment is necessary. Thus, the CNCs are extracted directly without the previous removal of lignin and hemicellulose. The main advantage of this method is the lower consumption of water, solvents and energy. On the other hand, marketing of acai pulp from the Amazonian region has had an accelerated growing in the internal and foreign markets because of the antioxidant, energetic and nutritious properties of the fruit. Consequently, the generation of biomass has been extrapolated, and the policies about better use of this resource are still modest, resulting in the random dispose and discard of these processing wastes and in environmental problems. This article presents a state- of-the-art of achievement on CNCs extraction through Ammonium Persulfate Oxidation of lignocellulosic biomass, and also the acai berry biomass.