ABSTRACT The Tunicata, despite the relatively low species diversity among the invertebrates, has always received attention not only due to their ecological importance, especially in fouling communities, but also for several species that are studied as models for genetics and the evolution of development, as well as being a prolific source of natural products. In Brazil, research during the last 60 years has considerably increased our knowledge of benthic and planktonic tunicates, resulting from the work of several research teams. In this review, we provide information on the biodiversity of coastal Brazil along with an analysis of geographic distribution, sampling effort, the locations and status of taxonomic collections, and research specialists working on this group. Tunicata invertebrates importance communities development products 6 tunicates teams review distribution effort collections group

ABSTRACT Objective: To assess the accuracy of general practitioners in recognizing diabetic retinopathy through color retinal retinography, with a two-hour training course, by comparing the capacity of screening and classifying diabetic retinopathy. Methods: In the first arm of the study, of 142 diabetic patients included, 274 eyes were evaluated, and these patients were examined with an indirect binocular ophthalmoscope and classified according to the degree of diabetic retinopathy. In the second arm of the study, 14 physicians who are not specialists in ophthalmology received two-hour training to diagnose diabetic retinopathy with color retinography, and the accuracy of these professionals in screening for diabetic retinopathy before and after the training course was measured using the photographic images obtained on the first front of the study. Results: There was a significant increase in sensitivity (82% to 99%) and specificity (44% to 83%) in detecting diabetic retinopathy by general practitioners, after attending the training. Conclusion: Qualified general practitioners can assess diabetic retinopathy through color retinography, and the screening program for this diabetes complication is a viable and beneficial proposal for the country. Objective retinography twohour two hour Methods study included 27 evaluated 1 Results 82% 82 (82 99% 99 44% 44 (44 83% 83 Conclusion country 2 8 (8 9 4 (4 (

RESUMO Objetivo: Avaliar a acurácia de médicos generalistas em reconhecer a retinopatia diabética por meio da retinografia colorida, com um curso de capacitação com duração de 2 horas, comparando a capacidade de rastrear e classificar a retinopatia diabética em relação ao exame presencial com oftalmologista. Métodos: No primeiro braço do estudo, de 142 pacientes diabéticos incluídos, avaliaram-se 274 olhos, em que esses pacientes foram examinados com oftalmoscópio binocular indireto e classificados quanto ao grau da retinopatia diabética. No segundo braço do estudo, 14 médicos não especialistas em oftalmologia receberam um treinamento de 2 horas para o diagnóstico de retinopatia diabética com a retinografia colorida e se aferiu a acurácia desses profissionais em rastrear a retinopatia diabética antes e depois do curso de capacitação, utilizando as retinografias obtidas na primeira frente do estudo. Resultados: Verificou-se aumento significativo da sensibilidade (82% para 99%) e da especificidade (44% para 83%) na detecção da retinopatia diabética pelos médicos generalistas, com o curso de capacitação. Conclusão: O médico generalista capacitado pode avaliar a retinopatia diabética por meio da retinografia colorida, sendo o programa de rastreamento dessa complicação do diabetes uma proposta viável e benéfica ao país. Objetivo oftalmologista Métodos estudo incluídos avaliaramse avaliaram 27 olhos 1 Resultados Verificouse Verificou 82% 82 (82 99% 99 44% 44 (44 83% 83 Conclusão país 8 (8 9 4 (4 (

Abstract Background: Vasovagal syncope (VVS) results in impaired quality of life (QoL). The response during the head-up tilt test (HUTT) influences QoL and recurrence. Objectives: To analyze the influence of the type of HUTT response on QoL in patients with VVS and recurrence of events after the exam. Methods: The SF-36 and Impact of Syncope on Quality of Life (ISQL) questionnaires were applied over 12 months after the HUTT. Unpaired Student's t test was used for differences between 2 groups of quantitative data with normal distribution. The recurrence of syncope episodes was analyzed using a Kaplan-Meier curve, and the log-rank test was applied to compare the curves regarding responses to the HUTT. Statistical significance was set at p value < 0.05. Results: We analyzed 82 patients (43.7 years old), 69% with previous recurrence (2.8 prior episodes). Cardioinhibitory response occurred in 46 patients; vasodepressor response occurred in 36, and 85.4% of patients received non-pharmacological treatment after the HUTT. During clinical follow-up, 43.9% had recurrence, mainly young patients (35.7 years; p = 0.002). On the SF-36, the best score was in functional capacity in men (p = 0.04) and patients without prior trauma (p = 0.001). There were lower limitations due to pain in patients without prior trauma (p = 0.003) and patients without prodromes (p = 0.009). On the ISQL, there were better mean scores in men (p = 0.002) and in patients without prior trauma (p = 0.02). Patients with cardioinhibitory response had better SF-36 and ISQL scores (p < 0.001). There was greater VVS recurrence in the cardioinhibitory response group (log-rank p = 0.011; hazard ratio: 8.48; 95% confidence interval: 7.59 to 9.3) from the second to the fourth month, with stabilization in the eighth month after the HUTT, when compared to patients with vasodepressor response. Conclusion: The majority of patients with VVS reproduced during the HUTT under non-pharmacological treatment did not report worsening of QoL during clinical follow-up. Worse QoL was observed in non-young patients and in patients with vasodepressor response, and it was not influenced by recurrence after the HUTT. Background (VVS QoL. . (QoL) headup head up (HUTT Objectives exam Methods SF36 SF 36 SF-3 (ISQL 1 Students Student s distribution KaplanMeier Kaplan Meier curve logrank log rank 005 0 05 0.05 Results 8 43.7 437 43 7 (43. old, old , old) 69 2.8 28 (2. episodes. episodes) 4 854 85 85.4 nonpharmacological non pharmacological followup, followup follow up, follow-up 439 9 43.9 35.7 357 35 (35. 0.002. 0002 0.002 002 SF36, 0.04 004 04 0.001. 0001 0.001 001 0.001) 0.003 0003 003 0.009. 0009 0.009 009 0.009) 0.02. 0.02 02 0.02) 0.011 0011 011 ratio 8.48 848 48 95 interval 759 59 7.5 9.3 93 3 Conclusion followup. up. nonyoung (QoL SF3 SF- 00 0.0 43. (43 6 2. (2 85. 35. (35 000 0.00 0.01 01 8.4 84 75 5 7. 9. 0. (4 ( (3 8.

Objective: To test the efficacy of a dissonance-based (DB) intervention in targeting risk factors for eating disorders (EDs) and predisposing factors for muscle dysmorphia (MD) symptoms in body-dissatisfied Brazilian men over 1 year of follow-up and evaluate whether reductions in body-ideal internalization would mediate the intervention’s impact on ED and MD symptoms. Methods: Participants were randomized to a two-session DB intervention (n=89) or assessment-only control (AOC) (n=91), and completed validated measures assessing body-ideal internalization, body dissatisfaction, ED, and MD symptoms at baseline, post-intervention, 1-month, 6-month, and 1-year follow-ups. Results: The DB condition showed significantly greater reductions in MD symptoms and body dissatisfaction compared with the AOC group over a 1-year follow-up, while significant differences were not observed for body-ideal internalization and ED symptoms. Changes in body-ideal internalization from baseline to 1-month follow-up completely mediated the relationship between condition and the changes observed in both ED and MD symptoms. Conclusion: These results provide further evidence of the efficacy of the tested intervention through 1-year follow-up in reducing body dissatisfaction and MD symptoms, but no such result was observed for body-ideal internalization and EDs. Our findings provide support for theoretical models of eating pathology and MD symptoms in Brazilian men. Clinical Trial Registration: Brazilian Registry of Clinical Trials (ReBEC): RBR-27dc264. Objective dissonancebased dissonance based (DB EDs (EDs (MD bodydissatisfied dissatisfied followup follow up bodyideal ideal interventions s Methods twosession two session n=89 n89 n 89 (n=89 assessmentonly assessment only (AOC n=91, n91 n=91 , 91 (n=91) postintervention, postintervention post intervention, post-intervention 1month, 1month month month, 6month, 6month 6 6-month 1year followups. followups ups. ups follow-ups Results followup, up, Conclusion Registration ReBEC (ReBEC) RBR27dc264. RBR27dc264 RBRdc RBR 27dc264. 27dc264 dc RBR-27dc264 n=8 n8 8 (n=8 n9 n=9 9 (n=91 (ReBEC RBR27dc26 27dc26 RBR-27dc26 n= (n= (n=9 RBR27dc2 27dc2 RBR-27dc2 (n RBR27dc 27dc RBR-27dc

ABSTRACT With the objective of evaluate the use of residues as growing media for the yellow passion fruit seedlings, a randomized block experiment was carried out with treatments distributed in a 2 × 21 factorial scheme corresponding to fertilizer management (presence and absence of controlled-release fertilizer), and combination of growing media from five local agro-industrial wastes (bark of cupuaçu fruit, almond shell of castanha-do-brasil, lumps of acerola fruit, lumps of cajá fruit, and lumps of açaí fruit) and a commercial growing media, which tested pure and was combined in a 1:1 ratio. The variables measured were the seedling height; stem diameter; height: stem diameter ratio; number of leaves; shoot, root, and total dry matter; and Dickson quality index. The dates were submitted to univariate and multivariate analyzes. The pairwise combination of growing medias produced from the bark of cupuaçu fruit, almond shell of castanha-do-brasil, lumps of acerola fruit, lumps of cajá fruit, lumps of açaí fruit, and commercial growing media in a proportion of 1:1 and with the use of controlled-release fertilizer constitute an alternative for other growing medias in the production of yellow passion fruit seedlings. seedlings presence controlledrelease controlled release fertilizer, , fertilizer) agroindustrial agro industrial castanhadobrasil, castanhadobrasil castanha do brasil, brasil castanha-do-brasil 11 1 1: ratio height leaves shoot root matter index analyzes

Resumo Introdução: O fígado gordo associado a disfunção metabólica (FGADM) é uma causa crescente de doença hepática crónica. Em 2020, o score Fibroscan-AST (FAST) foi validado internacionalmente como uma nova ferramenta capaz de identificar pacientes com esteatohepatite que beneficiam de terapêuticas adicionais, baseado nos achados da elastografia hepática transitória (EHT) e níveis séricos de aspartato aminotransferase (AST). Os autores procuraram identificar, em pacientes com FGADM, que fatores metabólicos predizem um score-FAST maior. Métodos: Estudo retrospetivo de pacientes com FGADM submetidos a EHT durante 2 anos consecutivos. Pacientes sem uma amostra de AST colhida nos 6 meses prévios à EHT foram excluídos. O score-FAST foi calculado, estratificando o risco do paciente como baixo (<0,35), moderado (0,35-0,67) ou alto (>0,67). Resultados: A amostra incluiu 117 pacientes, 53% do sexo feminino, com uma idade média de 53 anos. Em análise multivariada, pacientes com Diabetes Mellitus tipo 2 (DMT2) (p < 0,001), dislipidemia (p = 0,046) e hábitos tabágicos (p = 0,037) apresentaram valores de score-FAST significativamente maiores. Além disso, os pacientes diabéticos apresentaram não só valores de score-FAST significativamente maiores, como também foram mais frequente classificados como pertencendo ao grupo de alto risco, de acordo com os critérios deste score (OR = 9,2; 95%IC = 1,8-45,5; p = 0,007). Conclusões: Calculando o score-FAST, pacientes com FGADM e DMT2 apresentaram um risco significativamente maior. Esta ferramenta validada poderá ser utilizada para selecionar os pacientes com DMT2 e FGADM que poderão beneficiar de seguimento especializado.

Abstract Background: Metabolic-associated fatty liver disease (MAFLD) is an increasingly prevalent cause of chronic liver disease. In 2020, the FibroScan-AST (FAST) score was internationally validated as a new tool able to identify patients with steatohepatitis who benefit the most from further therapies, based on liver transient elastography (LTE) findings and serum levels of aspartate aminotransferase (AST). We aimed to identify, in MAFLD patients, which metabolic features may predict a higher FAST score. Methods: Retrospective study of consecutive patients with MAFLD submitted to LTE for two consecutive years. Patients without an AST sample collected within 6 months of the LTE were excluded. FAST score was calculated, stratifying the patient’s risk as low (<0.35), medium (0.35-0.67), or high (>0.67). Results: The sample included 117 patients, 53.0% of the female gender, with a mean age of 53 years. On multivariate analysis, patients with type 2 diabetes (T2DM) (p < 0.001), dyslipidemia (p = 0.046), and smoking habits (p = 0.037) presented with significantly higher FAST score values. Furthermore, diabetic patients did not only present significantly higher FAST scores but were also more frequently assigned to the high-risk group according to FAST score criteria (OR = 9.2; 95% CI = 1.8-45.5; p = 0.007). Conclusions: Calculating the FAST score, patients with T2DM presented a significantly higher risk of having significant fibrosis and steatohepatitis. Physicians may rely on this validated instrument to more easily identify which patients with T2DM and MAFLD benefit the most from a specialized follow-up.

RESUMO A dança em cadeira de rodas (DCR) é uma modalidade praticada principalmente por pessoas com deficiência física. No Brasil, é uma modalidade emergente que carece de investigação e sistematização. Assim, o objetivo do presente estudo foi, por meio de uma revisão narrativa da literatura, identificar, analisar e sistematizar os estudos existentes sobre os efeitos da DCR na saúde e qualidade de vida de pessoas com deficiência física. As pesquisas foram conduzidas em bases de dados especializadas, Catálogo de Teses e Dissertações da Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (Capes) e em bibliotecas digitais de teses e dissertações de inúmeras instituições de ensino superior. Estudos elegíveis incluíram apenas pessoas com deficiência física, assim como tratavam dos efeitos da DCR na saúde e qualidade de vida. Um total de oito estudos foram incluídos na síntese qualitativa. A maior parte dos estudos apresentou uma abordagem qualitativa e delineamento transversal. É possível concluir que a DCR pode trazer inúmeros benefícios para a saúde física, para o funcionamento psicossocial e para a qualidade de vida de pessoas com deficiência física.

ABSTRACT Wheelchair dancing (DCR) is an activity practised mainly by people with physical disabilities. In Brazil, it is an emerging activity lacking investigation and systematisation. Thus, the objective of the present study was, through a narrative review of the literature, to identify, analyse and systematise the existing studies about the effects of DCR on the health and quality of life of people with physical disabilities. The research was driven in specialised databases, the Theses and Dissertations Catalog of the Coordination for the Improvement of Higher Education Personnel (Capes), and digital libraries of theses and dissertations from numerous higher education institutions. Eligible studies included only people with physical disabilities, as well as dealing with the effects of DCR on health and quality of life. A total of eight studies were included in the qualitative synthesis. Most of the studies had a qualitative approach and cross-sectional design. It is possible to conclude that DCR can bring countless benefits to the physical health, psychosocial functioning and quality of life of people with physical disabilities.

ABSTRACT Objectives To evaluate predictors of muscle dysmorphia in sexual and gender minority Brazilian men and to describe community norms for the Muscle Dysmorphic Disorder Inventory (MDDI), an instrument for assessing muscle dysmorphia symptoms. Methods This cross-sectional study was carried out with 1.444 sexual and gender minority Brazilian men, with ages between 18 and 50 years. By means of an on-line survey the participants answered a sociodemographic questionnaire, as well as muscle dysmorphia symptoms, drive for muscularity, appearance-ideal internalization, and self-objectification measures. Descriptive and correlation (Spearman’s rho ) analysis were performed among the study variables, in addition to a multiple linear regression analysis (stepwise forward) to evaluate predictors of muscle dysmorphia. Results A positive and significant association of large magnitude was observed among muscle dysmorphia symptoms, drive for muscularity, appearance-ideal internalization, and self-objectification. Multiple linear regression showed that all these variables are predictors of muscle dysmorphia symptoms in sexual and gender minority Brazilian men. Conclusions Sexual and gender minority Brazilian men present high risk for muscle dysmorphia. Muscle dysmorphia symptoms were associated with drive for muscularity, appearance-ideal internalization, and self-objectification, showing that they are predictors of muscle dysmorphia. Interventions should target this population, considering the need to create strategies to reduce muscle dysmorphia symptoms, the drive for muscularity, appearance-ideal internalization, and self-objectification. MDDI, MDDI , (MDDI) crosssectional cross sectional 1444 1 444 1.44 5 years online on line questionnaire muscularity appearanceideal appearance ideal internalization selfobjectification self objectification measures Spearmans Spearman s stepwise forward selfobjectification. objectification. selfobjectification, objectification, population (MDDI 144 44 1.4 14 4 1.

RESUMO Objetivos Avaliar preditores de dismorfia muscular em homens brasileiros de minoria sexual e de gênero e descrever normas comunitárias para o Muscle Dysmorphic Disorder Inventory (MDDI), instrumento de avaliação de sinais e sintomas de dismorfia muscular. Métodos Trata-se de estudo transversal realizado com 1.444 homens brasileiros de minoria sexual e de gênero, com idade entre 18 e 50 anos. Por meio de uma pesquisa on-line , os participantes responderam a um questionário sociodemográfico, assim como medidas para avaliação dos sintomas de dismorfia muscular, busca pela muscularidade, internalização da aparência ideal e auto-objetificação. Foram realizadas análises descritivas e de correlação ( rho de Spearman) entre as variáveis do estudo, bem como uma análise de regressão linear múltipla ( stepwise forward ) para avaliar preditores de dismorfia muscular. Resultados Associação positiva e significante, de grande magnitude, foi observada entre os sintomas de dismorfia muscular, busca pela muscularidade, internalização da aparência ideal e auto-objetificação. Regressão linear múltipla demonstrou que todas essas variáveis são preditoras dos sintomas de dismorfia muscular em homens brasileiros de minoria sexual e de gênero. Conclusões Homens brasileiros de minoria sexual e de gênero apresentaram elevado risco para dismorfia muscular. Sintomas de dismorfia muscular estiveram associados com a busca pela muscularidade, internalização da aparência ideal e auto-objetificação, demonstrando que elas são preditoras de dismorfia muscular. Intervenções devem ser direcionadas a essa população, considerando a necessidade de criar estratégias de redução de sintomas de dismorfia muscular, da busca pela muscularidade, da internalização da aparência ideal e da auto-objetificação. MDDI, MDDI (MDDI) Tratase Trata se 1444 1 444 1.44 5 anos online on line sociodemográfico muscularidade autoobjetificação. autoobjetificação auto objetificação. objetificação auto-objetificação Spearman significante magnitude autoobjetificação, objetificação, população (MDDI 144 44 1.4 14 4 1.

Abstract Introduction mass contamination by the new coronavirus caused enough damage for the pandemic to extend indefinitely Objective the objective of this study was to analyze the emotional factors acquired by students from a dentistry course during the COVID-19 pandemic period and the influences related to the resumption of face-to-face activities. Material and method it is an observational, cross-sectional and analytical research conducted at a public university in the state of Pará, Brazil. A research questionnaire, prepared by the authors and validated by the ethics committee of the Federal University of Pará, was applied to the academic community for a period of three months (November 2020 to January 2021). The analysis was performed using the Excel program, Kappa statistics and the Chi-squared test, whose results were presented as frequency and percentage. Result a total of 188 dental students participated in the research. The findings proved to be in accordance with the hypothesis generated by the researchers, about 19.2% had emotional crises and 3.7% increase in the lockdown period. As for the expectations for care services, there was an increase in the oppressive state of psychic crises (anxiety, stress, anger, fear), considered influential in the cognition of behavioral traits during post-pandemic care. Conclusion the study identified that the emotional changes acquired in the pandemic outbreak had a negative impact on student performance; however, depressive symptoms were expressed in graduating students. COVID19 COVID 19 COVID-1 facetoface face activities observational crosssectional cross sectional Pará Brazil questionnaire November 202 2021. 2021 . 2021) program Chisquared Chi squared test percentage 18 researchers 192 2 19.2 37 3 7 3.7 services anxiety, anxiety (anxiety stress anger fear, fear , fear) postpandemic post performance however COVID1 1 COVID- 20 19. 3.

Resumo Introdução a contaminação em massa pelo novo coronavírus promoveu danos suficientes para que a pandemia se estendesse por tempo indeterminado. Objetivo analisar os fatores emocionais adquiridos por estudantes do curso de odontologia no período pandêmico COVID-19 e as influências relacionadas ao retorno das atividades presenciais. Material e método pesquisa observacional, transversal e analítica, realizada em uma universidade pública do estado do Pará. Foi aplicado na comunidade acadêmica um questionário de pesquisa, próprio, validado pelo comitê de ética da Universidade Federal do Pará, por um período de 3 meses (novembro de 2020 a janeiro de 2021). Para a análise foi pelo programa Excel, estatísticas Kappa e o teste Qui-quadrado exibidos por frequência e porcentagem. Resultado participaram da pesquisa 188 alunos de odontologia. Os resultados obtidos na pesquisa foram de acordo com a hipótese gerada pelos pesquisadores, cerca de 19,2% e 3,7%, apresentaram crises emocionais elevando-as no período de confinamento. Quanto as expectativas para o atendimento, houve aumento de estado opressivo de crises psíquicas (ansiedade, estresse, raiva, medo), consideradas influentes na cognição dos traços comportamentais durante o atendimento pós pandemia. Conclusão o estudo identificou que as alterações emocionais adquiridas no surto pandêmico desencadearam impacto negativo no rendimento estudantil, todavia, a sintomatologia depressiva esteve expressa em acadêmicos concluintes. indeterminado COVID19 COVID 19 COVID-1 presenciais observacional analítica Pará próprio novembro 202 2021. 2021 . 2021) Excel Quiquadrado Qui quadrado porcentagem 18 pesquisadores 192 2 19,2 37 7 3,7% elevandoas elevando confinamento ansiedade, ansiedade (ansiedade estresse raiva medo, medo , medo) estudantil todavia concluintes COVID1 1 COVID- 20 19, 3,7 3,

ABSTRACT Purpose to review the national and international literature regarding instruments, methods and techniques for language assessment in visually impaired children. Research strategy searches in the VHL, PUBMED and SCOPUS databases using the descriptors vision disorders, child language, low vision, blindness, speech-language pathology and rehabilitation. Selection criteria articles published in national and international journals, in English, Spanish and Portuguese. Studies that were unavailable for reading, with a sample other than children, not addressing the subject, or that reported sensory impairments associated with visual impairments were excluded. Studies that dealt with intervention were also excluded, except for those that also addressed assessment. The references of the articles read in full were selected according to these criteria. The investigators evaluated the proposed assessment instruments/methods/techniques, as well as the objectives of the studies, their samples and main results. Results 157 articles were retrieved, of which 6 were selected for full reading based on the exclusion criteria, and another 6 studies were obtained from their references, thus totaling 12 articles. Seven studies involved preschool and blind children, with various assessment instruments/methods/techniques, ranging from assessments of specific linguistic levels to socio-communicative skills. The objectives of the studies were related to the comparison between the development of children with and without visual impairment. Conclusion the review provided contributions to analyses of the language assessment of visually impaired children, such as the use of the remaining senses; no study had an instrument to assess language levels in schoolchildren with VI. instruments VHL disorders blindness speechlanguage speech rehabilitation journals English Portuguese subject excluded instrumentsmethodstechniques instruments/methods/techniques results 15 retrieved 1 sociocommunicative socio communicative skills impairment senses VI

RESUMO Objetivo revisar a literatura nacional e internacional a respeito dos instrumentos, métodos e técnicas para avaliação de linguagem de crianças com deficiência visual. Estratégia de pesquisa foram realizadas buscas nas bases BVS, PubMed e Scopus, utilizando-se os descritores transtornos da visão, linguagem infantil, baixa visão, cegueira, fonoaudiologia e reabilitação. Critérios de seleção artigos publicados em periódicos nacionais e internacionais, nos idiomas inglês, espanhol e português. Trabalhos indisponíveis para leitura, com amostra composta por não crianças, não pertencentes ao assunto abordado, ou que mencionassem deficiências sensoriais associadas à visual, foram excluídos. Foram também excluídos os artigos que versassem sobre intervenção, salvo os que também abordassem a avaliação. As referências dos artigos lidos na íntegra foram selecionadas de acordo com esses critérios. Analisaram-se os instrumentos/métodos/técnicas de avaliação propostos, os objetivos dos estudos, sua amostra e principais resultados obtidos. Resultados foram recuperados 157 artigos, dos quais, selecionaram-se, a partir dos critérios de exclusão, 6 para leitura integral, e mais 6 obtidos de suas referências, totalizando 12 artigos. Sete trabalhos foram realizados com crianças pré-escolares e cegas e os instrumentos/métodos/técnicas de avaliação foram variados, contemplando desde avaliações de níveis linguísticos específicos, até habilidades sociocomunicativas. Os objetivos dos estudos relacionaram-se à comparação entre o desenvolvimento da criança com deficiência visual e vidente. Conclusão a revisão trouxe contribuições para pensar a avaliação da linguagem de crianças com deficiência visual, como a utilização dos sentidos remanescentes; nenhum estudo apresentou instrumento para avaliação de níveis da linguagem em crianças escolares com deficiência visual. instrumentos BVS Scopus utilizandose utilizando se visão infantil cegueira reabilitação internacionais inglês português abordado intervenção Analisaramse Analisaram instrumentosmétodostécnicas propostos 15 quais selecionaramse, selecionaramse selecionaram se, selecionaram-se exclusão integral 1 préescolares pré variados específicos sociocomunicativas relacionaramse relacionaram vidente remanescentes

Abstract Introduction The Strengthening and Stretching for Rheumatoid Arthritis of the Hand (SARAH) program is a personalized, progressive 12-week exercise program for people with hand problems due to rheumatoid arthritis (RA). Patients are provided with two guidance documents, the ‘Patient Exercise Booklet’ and the ‘Personal Exercise Guide’, to continue the exercises independently at home. Objective This study aimed to translate and culturally adapt the SARAH protocol into Brazilian Portuguese and validate its content. Methods The guidance documents ‘Patient Exercise Booklet’ and ‘Personal Exercise Guide’ of the SARAH program were translated and culturally adapted to Brazilian Portuguese. The content validity was obtained by calculating the content validity index (CVI). Results The Brazilian version of the SARAH protocol reached semantic, idiomatic, conceptual, and cultural equivalences. The CVI was greater than 0.8, corresponding to a satisfactory index. The verbal comprehension was 4.9, showing good verbal comprehension ofthe target population. Conclusion The Brazilian Portuguese version of the SARAH protocol is available to Brazilian people with compromised hands due to RA with satisfactory content validity. (SARAH personalized 12week week 12 RA. . (RA) Patient Booklet Personal Guide, Guide , home CVI. (CVI) semantic idiomatic conceptual equivalences 08 0 8 0.8 49 4 9 4.9 population 1 (RA (CVI 0. 4.

Abstract Photosynthetic phosphoenolpyruvate carboxylase (PEPC) catalyses the irreversible carboxylation of phosphoenolpyruvate (PEP), producing oxaloacetate (OAA). This enzyme catalyses the first step of carbon fixation in C4 photosynthesis, contributing to the high photosynthetic efficiency of C4 plants. PEPC is also involved in replenishing tricarboxylic acid cycle intermediates, such as OAA, being involved in the C/N balance. In plants, PEPCs are classified in two types: bacterial type (BTPC) and plant-type (PTPC), which includes photosynthetic and non-photosynthetic PEPCs. During C4 evolution, photosynthetic PEPCs evolved independently. C4 PEPCs evolved to be highly expressed and active in a spatial-specific manner. Their gene expression pattern is also regulated by developmental cues, light, circadian clock as well as adverse environmental conditions. However, the gene regulatory networks controlling C4 PEPC gene expression, namely its cell-specificity, are largely unknown. Therefore, after an introduction to the evolution of PEPCs, this review aims to discuss the current knowledge regarding the transcriptional regulation of C4 PEPCs, focusing on cell-specific and developmental expression dynamics, light and circadian regulation, as well as response to abiotic stress. In conclusion, this review aims to highlight the evolution, transcriptional regulation by different signals and importance of PEPC in C4 photosynthesis and its potential as tool for crop improvement. (PEPC PEP, PEP , (PEP) OAA. OAA . (OAA) C plants intermediates CN N balance types BTPC (BTPC planttype plant PTPC, PTPC (PTPC) nonphotosynthetic non independently spatialspecific spatial specific manner cues conditions However cellspecificity, cellspecificity cell specificity, specificity cell-specificity unknown Therefore cellspecific dynamics stress conclusion improvement (PEP (OAA (PTPC

ABSTRACT The present study aimed to analyze the influence of the media in professional football by considering the perception of clubs’ coaches and communication advisors. The sample consisted of a group of five communication advisors and seven coaches from Portuguese football clubs, to whom a semi-structured interview from the first and second leagues was applied. The responses obtained were analyzed using a qualitative content analysis methodology. The results obtained show that the media are positioned as an important influencing factor in the players’ performance. The massification of information and sports content as well as the transformation process that sports communication goes through thus positioned them. Due to the unequivocal effect of the media, some coaches report an environment of tension around their players, which has led to the application of psychological and communicational strategies capable of motivating their athletes towards success. However, the interviewees’ perception of the importance of being continuously informed is relevant, causing a need for closer monitoring. The solution offered was internal training for professional football players and coaches in order to obtain a better communication efficiency for the clubs. We found, in short, that the media advisors and coaches interviewed consider the media to be a relevant factor of influence over professional football, with the potential to provoke teams, namely, lack of confidence, cohesion and tension.

RESUMO O presente estudo teve como objetivo analisar a influência dos media no futebol profissional considerando a perceção dos treinadores e dos assessores de comunicação dos clubes. A amostra foi constituída por um grupo de cinco assessores de comunicação e sete treinadores de clubes portugueses de futebol de primeira e segunda Liga, aos quais foram aplicadas entrevistas semiestruturadas. As respostas obtidas foram analisadas, utilizando uma metodologia qualitativa de análise de conteúdo. Os resultados obtidos mostram que os media posicionam-se como um importante fator de influência no desempenho dos jogadores dada não só, a massificação de informação e conteúdos desportivos como também, o processo de transformação que a comunicação desportiva atravessa. Por efeito inequívoco dos media, alguns treinadores relatam um ambiente de tensão em torno dos seus jogadores, o que tem conduzido à aplicação de estratégias psicológicas e comunicacionais capazes de motivar os seus atletas rumo à obtenção de sucesso. Contudo, é relevante a perceção dos entrevistados, sobre a importância de se manterem continuamente informados provocando, uma necessidade de um acompanhamento mais próximo. A realização de formação interna aos jogadores e treinadores de futebol profissional para obtenção de uma melhor eficácia da comunicação dos clubes foi uma solução apresentada. Constatamos, em suma, que os assessores de comunicação e os treinadores entrevistados consideram os media um fator relevante de influência sobre o futebol profissional, com potencial de provocar nas equipas, nomeadamente, estados de falta de confiança, coesão e tensão.

Abstract Introduction: In order to optimize the rate of adequate cleansing in colon capsule, it may be important to identify risk factors that can predict a suboptimal colon preparation. Aim: To define predictive factors for inadequate bowel preparation in colon capsule, according to CC-CLEAR (Colon Capsule CLEansing Assessment and Report). Methods: Retrospective, single center, cohort study. Patients’ demographics, data, and quality of bowel preparation, according to CC-CLEAR, were collected retrospectively. A univariate analysis tested the association between covariables and the outcome, inadequate cleansing. The statistically significant variables were included in multivariable logistic binary regression, and a receiver operating characteristic curve (ROC) assessment was performed. Results: We included 167 consecutive colon capsules. Sixty-eight percent (n = 114) of patients were female, with a mean age of 64 years. The main indication for colon capsule was previous incomplete colonoscopy, in 158 patients (94.6%). The colon capsules cleansing was graded as good or excellent in 96 patients (57.5%) and as inadequate in 71 (42.5%), according to CC-CLEAR. The variables inadequate previous colon cleansing (OR adjusted 41.72 [95% CI 12.57-138.57], p value < 0.001); chronic laxative (OR adjusted 4.86 [95% CI 1.08-21.79], p value = 0.039); antidepressant (OR adjusted 5.00 [95% CI 1.65-15.16], p value = 0.004), and impaired mobility (OR adjusted 5.54 [95% CI 1.17-26.31], p value = 0.031) were independently associated with the outcome inadequate cleansing, after adjusting for confoundment. The model presented an excellent discriminative power towards the outcome variable (AUC ROC 0.937 [CI 95% 0.899-0.975], p value < 0.001). Conclusion: A previous inadequate colon cleansing, the use of chronic laxative and antidepressant, or impaired mobility are predictors of inadequate colon capsule cleansing, as assessed by the CC-CLEAR. These 4 predictors come together as a model enabling an accurate categorization of the patients at major risk of inadequate bowel preparation for capsule colonoscopy, with an excellent discriminative power and performance, which seems useful for the selection of patients for tailored optimization of the colon cleansing protocol.

Resumo Introdução: Com o intuito de otimizar a taxa de preparações intestinais adequadas em cápsula do cólon, poderá ser importante identificar fatores de risco preditivos de preparações sub-ótimas. Objetivo: Definir fatores preditivos de preparação intestinal inadequada em cápsula do colon, de acordo com a CC-CLEAR (Colon Capsule CLEansing Assessment and Report). Métodos: Estudo de coorte retrospetivo, no qual as variáveis demográficas, clínicas e a qualidade de preparação intestinal, de acordo com a CC-CLEAR, foram colhidas retrospetivamente. Uma análise univariada testou a associação entre as covariáveis e a variável outcome - preparação intestinal inadequada. As variáveis estatisticamente significativas foram incluídas num modelo de regressão logística binária e performance testada com a realização de curva ROC. Resultados: Incluímos 167 cápsulas do colon consecutivas. Sessenta e oito por cento (n = 114) eram do sexo feminino, com idade média de 64 anos. A principal indicação para cápsula do colon foi uma colonoscopia prévia incompleta, em 158 indivíduos (94.6%). As preparações intestinais em cápsula do colon foram classificadas como boas ou excelentes em 96 indivíduos (57.5%) e como inadequadas em 71 (42.5%), de acordo com a CC-CLEAR. As variáveis preparação cólica prévia inadequada [OR ajustado 41.72 (95% CI 12.57-138.57) valor p < 0.001]; uso crónico de laxante [OR ajustado 4.86 (95% CI 1.08-21.79) valor p = 0.039]; antidepressivo [OR ajustado 5.00 (95% CI 1.65-15.16) valor p = 0.004] e défice de mobilidade [OR ajustado 5.54 (95% CI 1.17-26.31) valor p = 0.031] foram independentemente associadas ao outcome, preparação intestinal inadequada, após o ajuste para o confundimento. O modelo apresentou um excelente poder discriminativo em relação ao outcome [AUC ROC 0.937 (CI95% 0.899-0.975) valor p < 0.001]. Conclusão: Umapreparação cólica prévia inadequada, o uso crónico de laxantes e antidepressivos e um défice de mobilidade são preditores de preparação intestinal inadequada em cápsula do cólon, de acordo com a CC-CLEAR. Estas 4 variáveis formam um modelo que permite a categorização, com excelente acuidade, de indivíduos com risco elevado para preparação intestinal ina dequada em cápsula do colon, o que parece ser útil para uma otimização caso a caso do protocolo de preparação intestinal.

Resumo A doença de Freiberg é rara, e seu diagnóstico requer alto grau de suspeita clínica. A necrose avascular da cabeça do metatarso progride com colapso articular, e causa dor no antepé e limitação da atividade. Há diversas técnicas cirúrgicas para o tratamento da doença; como o diagnóstico geralmente é feito em estágios posteriores, a maioria dessas técnicas inclui procedimentos de destruição articular. A artroscopia tem sido utilizada nas pequenas articulações do pé nos últimos anos, mas sua aplicação na doença de Freiberg ainda é escassa. Procedimentos de preservação articular têm sido preconizados na doença em estágio inicial, com o objetivo de aliviar os sintomas e impedir a progressão. Neste relato, descrevemos o tratamento bem-sucedido de uma paciente de 12 anos de idade com doença de Freiberg em estágio inicial por meio de descompressão central e enxerto de medula óssea, por meio de abordagem minimamente invasiva assistida por artroscopia.

Abstract Freiberg disease is a rare condition whose diagnosis requires a high clinical suspicion. Avascular necrosis of the metatarsal head progresses with articular collapse, leading to forefoot pain and limitation of the daily activities. Several surgical techniques have been described to address the disease, and since it is usually diagnosed in later-stages, most of them include joint-destructive procedures. The use of arthroscopy on the small joint of the foot has arisen in the last few years, but its application in Freiberg disease is still scant. Joint-preserving procedures have been advocated for cases of early-stage disease, aiming to relieve symptoms while preventing the progression of the disease. In the present report, we describe a successful treatment of a 12-year-old patient with early-stage Freiberg disease using core decompression and bone marrow graft through a minimally-invasive approach assisted by arthroscopy.