The use of materials such as organofunctionalized silica for application in solid phase extraction (SPE) allows the preconcentration of several ions, including Pt, and subsequent detection. This work aims to synthesize and characterize an organofunctionalized silica (Sil-TMSDT) with the silylant N’(trimethoxysilyl)propylethylenetriamine and its application as a solid phase in the preconcentration Pt4+ ions in aqueous media, using detection by flame atomization atomic absorption spectroscopy (FAAS). The Fourier-transform infrared spectroscopy (FTIR) spectra and scanning electron microscopy (SEM) coupled with energy-dispersive spectroscopy (EDS) confirmed the aminofunctionalization of the silica. For the adsorption process, a preconcentration mini-column with 200 mg of Sil-TMSDT, a solution of 0.485 mg L−1 of K2[PtCl6] at pH 10 and HNO3 0.5 mol L−1 as eluent were used, obtaining an enrichment factor of 15-fold with retention efficiency higher than 99%. The Pt4+ ion determined by FAAS showed a linear response between 0.02 and 0.40 mg L−1; a linear coefficient where R = 0.9981; a 16-fold preconcentration factor; a limit of quantification (LOQ) and limit of detection (LOD) of 0.045 and 0.014 mg L−1, respectively. The proposal system showed analytical applicability to determining Pt4+ ion in an aqueous medium and could be used to detect traces of this potentially toxic metal in biological fluids such as urine and blood. SPE (SPE Pt SilTMSDT Sil TMSDT (Sil-TMSDT Ntrimethoxysilylpropylethylenetriamine N trimethoxysilyl propylethylenetriamine Pt4 media FAAS. . (FAAS) Fouriertransform Fourier transform FTIR (FTIR SEM (SEM energydispersive energy dispersive EDS (EDS process minicolumn mini column 20 SilTMSDT, TMSDT, Sil-TMSDT 0485 0 485 0.48 L1 L 1 L− K2PtCl6 KPtCl K2 PtCl6 K PtCl K2[PtCl6 HNO 05 5 0. 15fold fold 15 99 99% 002 02 0.0 040 40 0.4 0.9981 09981 9981 16fold 16 LOQ (LOQ LOD (LOD 0045 045 0.04 0014 014 0.01 respectively blood (FAAS 2 048 48 K2PtCl K2[PtCl 9 00 04 4 0.998 0998 998 004 001 01 0.99 099 0.9 09

ABSTRACT The aim of this study was to evaluate development in the following tree species: Acacia mangium Willd, Anadenanthera colubrina var. cebil (Griseb.) Altschu, Casuarina equisetifolia L. ex J. R. Forst. & G. Forst, Handroanthus impetiginosus (Mart. Ex DC.) Mattos, and Colubrina glandulosa subsp. reitzii (M.C.Johnst.) Borhidi under two water regimes in the Irrigated Perimeter of Baixo Acaraú, in the state of Ceará. The experiment was conducted over seven years, with the factors represented by water regimes, species and periods in an arrangement of split-split plots in a completely randomised design repeated over time with four replications of two plants each. The response variables were total height, diameter at breast height, volume, absolute growth rate in height and diameter, and current and average annual increase in volume. After seven years, the species Acacia mangium, Casuarina equisetifolia, Handroanthus impetiginosus, Anadenanthera colubrina and Colubrina glandulosa presented the following respective mean volumes: 0.62, 0.47, 0.45, 0.31 and 0.29 m3 irrespective of the water regime. Despite a reduction in the growth rates of the species during each period, they remained positive, and growth did not stop. The mean values for volume confirm that the species showed similar growth for the water regimes under study. An irrigated regime of up to one year is therefore suggested for cultivating these species in the Irrigated Perimeter of Baixo Acaraú, Ceará. Willd var Griseb. Griseb (Griseb. Altschu L J R Forst G Mart. Mart (Mart DC. DC Mattos subsp M.C.Johnst. MCJohnst M C Johnst (M.C.Johnst. Acaraú Ceará years splitsplit split volumes 062 0 62 0.62 047 47 0.47 045 45 0.45 031 31 0.3 029 29 0.2 m period positive stop (Griseb M.C.Johnst (M.C.Johnst 06 6 0.6 04 4 0.4 03 3 0. 02 2

RESUMO: A leptospirose é uma doença zoonótica que deve ser estudada sob o ponto de vista da Saúde Única. É possível que existam particularidades na epidemiologia da leptospirose no bioma Caatinga, onde o ambiente é muitas vezes desfavorável e desafia a adaptabilidade de Leptospira spp. No total, 100 cães (47 de abrigos e 53 errantes) selecionados com base em cálculo amostral foram utilizados para avaliar a soroprevalência de Leptospira spp. e os fatores associados. O teste de soroaglutinação microscópica (SAM) foi aplicado para detetar anticorpos anti-Leptospira spp. (título 50 como ponto de corte). Os fatores de risco foram identificados utilizando a análise de regressão de Poisson robusta. Vinte e quatro animais (24%; IC 95% = 15,6% - 32,4%) foram soropositivos, os títulos de anticorpos variaram de 50 a 200, e os serogrupos reagentes foram Ballum (17%), Autumnalis (6%) e Djasiman (1%). Os fatores/categorias associados à seropositividade foram o ambiente onde o animal se encontra/solo (razão de prevalência [RP] = 6,03; IC 95% para RP: 1,86 - 7,69; P < 0,001) e o acesso a água poluída/sim (RP = 3,79; IC 95% para RP: 1,85 - 24,22; P = 0,011). Os resultados sugerem a leptospirose como uma preocupação no contexto da Saúde Única em cães errantes e de abrigos no bioma Caatinga, apesar das condições adversas desse bioma para a sobrevivência de Leptospira spp. no ambiente. Além disso, apesar de serem questões sociais e governamentais, fatores como o ambiente onde o animal fica (solo) e o acesso à água poluída devem ser cuidadosamente analisados e corrigidos para evitar a transmissão de leptospiras para animais e humanos. RESUMO Caatinga spp total 10 47 (4 5 SAM (SAM antiLeptospira anti título corte. corte . corte) robusta 24% 24 (24% 95 156 15 6 15,6 32,4% 324 32 4 soropositivos 200 17%, 17 17% , (17%) 6% (6% 1%. 1 1% (1%) fatorescategorias categorias encontrasolo encontra solo razão RP [RP 6,03 603 03 186 86 1,8 7,69 769 7 69 0,001 0001 0 001 poluídasim sim 3,79 379 3 79 185 85 24,22 2422 22 0,011. 0011 0,011 011 0,011) disso governamentais (solo humanos ( 2 (24 9 15, 32,4 20 (17% (6 (1% 6,0 60 18 8 1, 7,6 76 0,00 000 00 3,7 37 24,2 242 0,01 01 (2 32, (17 (1 6, 7, 0,0 3, 24, 0,

ABSTRACT: Leptospirosis is a zoonotic disease that must be studied on the One Health point of view. It is possible that there are particularities in the epidemiology of leptospirosis in Caatinga biome, where the environment is often unfavorable and challenges the adaptability of Leptospira spp. Overall, 100 dogs (47 shelter and 53 stray dogs) selected based on sampling calculation were used to evaluate the Leptospira spp. seroprevalence and associated factors. The microscopic agglutination test (MAT) was applied to detect anti-Leptospira spp. antibodies (cut-off titer 50). Risk factors were identified using the robust Poisson regression analysis. Twenty-four animals (24%; 95% CI = 15.6% - 32.4%) were seroreactive, antibody titers ranged from 50 to 200, and the reacting serogroups were Ballum (17%), Autumnalis (6%) and Djasiman (1%). The factors/categories associated with seropositivity were the environment where the animal stay/soil (prevalence ratio [PR] = 6.03; 95% CI for PR: 1.86 - 7.69; P < 0.001) and access to polluted water/yes (PR = 3.79; 95% CI for PR: 1.85 - 24.22; P = 0.011). The results suggested leptospirosis as a concern in the One Health context in stray and shelter dogs from the Caatinga biome despite the adverse conditions of this biome for the survive of Leptospira spp. on the environment. Moreover, despite being social and government issues, factors such as environment where the animal stay (soil) and access to polluted water must be carefully deemed and corrected to avoid the transmission of leptospires to animals and humans. ABSTRACT view spp Overall 10 47 (4 5 MAT (MAT antiLeptospira anti cutoff cut off 50. . 50) analysis Twentyfour Twenty four 24% 24 (24% 95 156 15 6 15.6 32.4% 324 32 4 seroreactive 200 17%, 17 17% , (17%) 6% (6% 1%. 1 1% (1%) factorscategories categories staysoil soil prevalence PR [PR 6.03 603 03 186 86 1.8 7.69 769 7 69 0.001 0001 0 001 wateryes yes 3.79 379 3 79 185 85 24.22 2422 22 0.011. 0011 0.011 011 0.011) Moreover issues (soil humans ( 2 (24 9 15. 32.4 20 (17% (6 (1% 6.0 60 18 8 1. 7.6 76 0.00 000 00 3.7 37 24.2 242 0.01 01 (2 32. (17 (1 6. 7. 0.0 3. 24. 0.

ABSTRACT The cowpea is a legume that is widely grown in the north-east of Brazil, and which has been gaining ground in other regions of the country. The main producer is the state of Ceará, with a large planted-area, albeit low productivity due to a lack of producer technology and adapted cultivars. The aim of this study was to identify and recommend superior genotypes in terms of adaptability and stability under rainfed and irrigated conditions, in addition to genotypes with reduced grain darkening. To this end, six experiments were conducted in different districts of Ceará (Crato, Pentecoste, Crateús, Madalena, Bela Cruz and Limoeiro do Norte) and one laboratory experiment, to evaluate grain darkening. The experimental design of the field trials was of randomised blocks, with 14 genotypes and 4 replications. The analysis of variance showed a significant effect from the genotypes and environments and their interaction, so GGE Biplot analysis was carried out to evaluate adaptability and stability. To evaluate grain darkening, a completely randomised design was used in a simple factorial scheme with six previously selected genotypes and five different storage times (0, 2, 4, 6 and 8 months). There was a significant effect from the genotypes and storage time. Genotype 1 showed the least darkening, and can be recommended for environments to which it is best adapted (Crato and Crateús). Genotype 9 was considered the most stable for grain yield, and can be more broadly recommended for the semi-arid region of the state of Ceará. northeast north east Brazil country plantedarea, plantedarea planted area, area planted-area cultivars conditions darkening end Crato, Crato Pentecoste Crateús Madalena Norte experiment blocks replications interaction 0, 0 (0 2 months. months . months) time Crateús. Crateús) yield semiarid semi arid (

Computational predictive approaches present themselves as an attractive alternative in the search for new compounds that may present toxic or growth regulatory activity in Aedes aegypti. Aspergillus species is a producer of secondary metabolites with diverse biological activities. In this study, it was possible to evaluate the pharmacokinetic and toxicological properties in silico, as well as the prediction of the insecticidal biological activities of the juvenile hormone of natural substances produced by the genus Aspergillus. Initially, 187 molecules were cataloged from various species of Aspergillus spp., and only seven molecules of indole alkaloids were found to exhibit a toxic dose 50% (TD50) after conducting toxicity predictions. The molecular dynamic simulation trajectories were utilized to study parameters such as root mean square deviation, root mean square fluctuation, radius of gyration and intermolecular hydrogen bond to understand the behavior and stability of proposed compounds in the binding pocket of the target protein. The N-β-acetyltryptamine molecule showed a binding affinity value of –8.100 ± 0.200 kcal mol-1, which classifies the compound as a potential insecticidal agent against the Aedes aegypti vector. silico Initially 18 spp spp. 50 TD50 TD (TD50 predictions deviation fluctuation protein Nβacetyltryptamine N β acetyltryptamine 8100 8 100 –8.10 0200 0 200 0.20 mol1, mol1 mol 1, 1 mol-1 vector 5 TD5 (TD5 810 10 –8.1 020 20 0.2 mol- (TD 81 –8. 02 2 0. –8 –

RESUMO Objetivo: descrever a condição miofuncional orofacial global de pacientes com traumatismos faciais e analisar aspectos posturais e de mobilidade relacionados à função deglutição em diferentes etapas de recuperação. Métodos: estudo analítico e transversal. 36 participantes, idade entre 19 e 67 anos. Realizada em cinco etapas (D1, D2, D3, D4 e D5): oitavo ao sexagésimo dia após trauma. Utilizou-se o Protocolo de Avaliação Miofuncional Orofacial com Escores (AMIOFE) adaptado. Foi realizada análise estatística descritiva e inferencial, utilizando os testes t-Student pareado ou teste Wilcoxon pareado e o teste de Friedman na comparação entre as cinco avaliações. A margem de erro utilizada na decisão dos testes estatísticos foi de 5%. Resultados: nos movimentos labiais a maioria (69,4%) tinha inabilidade severa. Nos movimentos da língua, as duas categorias relacionadas, falta de precisão e inabilidade severa, apresentaram percentuais de 52,8% e 41,7%, respectivamente. Na movimentação da mandíbula, a maioria (83,3%) apresentava inabilidade severa. No escore AMIOFE, a mediana foi menos elevada em D1 (29,00), seguida por D2 (33,00), mais elevada em D5 (46,00) e variou de 39,50 a 41,00 nas outras duas avaliações com diferenças significativas entre: D1 diferente de D3, D4 e D5 e D2 diferente de D5. Conclusão: houve evolução positiva espontânea da condição miofuncional orofacial ao longo das avaliações. Contudo, é necessária atenção dos profissionais envolvidos. Objetivo recuperação Métodos transversal 3 participantes 1 6 anos D1, D (D1 D3 D5) trauma Utilizouse Utilizou se AMIOFE (AMIOFE adaptado inferencial tStudent t Student 5 5% Resultados 69,4% 694 69 4 (69,4% severa língua relacionadas 528 52 8 52,8 417 41 7 41,7% respectivamente mandíbula 83,3% 833 83 (83,3% 29,00, 2900 29,00 , 29 00 (29,00) 33,00, 3300 33,00 33 (33,00) 46,00 4600 46 (46,00 3950 39 50 39,5 4100 41,0 Conclusão Contudo envolvidos (D 69,4 (69,4 52, 41,7 83,3 (83,3 290 29,0 2 0 (29,00 330 33,0 (33,00 46,0 460 (46,0 395 39, 410 41, 69, (69, 83, (83, 29, (29,0 33, (33,0 46, (46, (69 (83 (29, (33, (46 (6 (8 (29 (33 (4 ( (2 (3

ABSTRACT Purpose: to describe the global orofacial myofunctional condition of patients presented with facial trauma and analyze postural and mobility aspects related to swallowing function at different stages of recovery. Methods: an analytical and cross-sectional study with 36 participants, aged 19 to 67 years, conducted in five stages (D1, D2, D3, D4, and D5), on the 8th to 60th day after trauma, using the adapted Orofacial Myofunctional Evaluation Protocol with Scores (OMES). Descriptive and inferential statistical analysis was performed using the paired Student's t-test or paired Wilcoxon test, and the Friedman test which compared the five evaluations. A 5% margin of error was used in the decision of the statistical tests. Results: in lip movements, the majority (69.4%) had severe inability. In tongue movements, the two related categories (imprecise and severe inability) had percentages of 52.8% and 41.7%, respectively. In jaw movements, the majority (83.3%) had severe inability. The median OMES score was lowest in D1 (29.00), followed by D2 (33.00), highest in D5 (46.00), and ranged from 39.50 to 41.00 in the other two evaluations, with significant differences between D1 and D3, D4 and D5, and D2 and D5. Conclusion: the orofacial myofunctional condition progressed, spontaneously and positively, throughout the evaluations. However, attention is needed from the professionals involved. Purpose recovery Methods crosssectional cross sectional 3 participants 1 6 years D1, D (D1 D3 , D5) th OMES. . (OMES) Students Student s ttest t evaluations 5 tests Results movements 69.4% 694 69 4 (69.4% inability imprecise 528 52 8 52.8 417 41 7 41.7% respectively 83.3% 833 83 (83.3% 29.00, 2900 29.00 29 00 (29.00) 33.00, 3300 33.00 33 (33.00) 46.00, 4600 46.00 46 (46.00) 3950 39 50 39.5 4100 41.0 Conclusion progressed positively However involved (D (OMES 69.4 (69.4 52. 41.7 83.3 (83.3 290 29.0 2 0 (29.00 330 33.0 (33.00 460 46.0 (46.00 395 39. 410 41. 69. (69. 83. (83. 29. (29.0 33. (33.0 46. (46.0 (69 (83 (29. (33. (46. (6 (8 (29 (33 (46 ( (2 (3 (4

ABSTRACT Purpose: This study aimed to evaluate the total macular thickness as well as the thickness of the inner and outer retinal layers in patients with Parkinson’s disease. It also aimed to verify the correlation of these parameters with motor symptoms and cognitive function. Methods: A total of 46 eyes of 23 patients with Parkinson’s disease and 40 eyes of 20 healthy controls were included in the study. The patients’ cognitive, functional, and nonmotor symptoms were evaluated using the Katz Index of Independence and Pfeffer’s Activities of Daily Living, Mini-Mental State Examination, Frontal Assessment Battery, Schwab and England Staging Scales, and Movement Disorders Society Nonmotor Symptoms Scale. The macular thickness measurements obtained via total, inner, and outer optical coherence tomography were recorded. Furthermore, the correlation of the parameters of optical coherence tomography with cognitive, functional, and nonmotor symptoms was assessed. Results: The scores of the Katz Index of Independence and Pfeffer’s Activities of Daily Living as well as the Movement Disorders Society Nonmotor Symptoms Scale were significantly lower in patients with Parkinson’s disease than in healthy controls. Moreover, the former had greater total macular thickness. The temporal and inferior outer sectors were significantly greater for the ganglion cell complex thickness in patients. A significant correlation was observed between the total macular thickness and the Movement Disorder Society-Unified Parkinson’s Disease Rating Scale, Parte III (MDS-UPDRS-III) values. Contrarily, there was a negative correlation between the outer macular thickness and the MDS-UPDRS-III values. Meanwhile, the total macular thickness and ganglion cell complex thickness were significantly correlated with the scores of the Mini-Mental State Examination, Schwab and England Staging Scale, Frontal Assessment Battery, and Katz Index of Independence and Pfeffer’s Activities of Daily Living. In addition, the Schwab and England scale was correlated with the outer macular thickness. Conclusion: The total and inner macular thicknesses at the temporal and inferior outer sectors were greater in patients with Parkinson’s disease than in the control group. These findings indicate that macular thickness may be greater in those with Parkinson’s disease, particularly when associated with mild motor symptoms. In addition, the parameters of the total, inner, and outer optical coherence tomography were significantly associated with motor and nonmotor symptoms as well as cognitive function impairment. Purpose Parkinsons Parkinson s Methods 4 2 functional Pfeffers Pfeffer MiniMental Mini Mental Examination Battery Scales recorded Furthermore assessed Results Moreover SocietyUnified Unified MDSUPDRSIII MDS UPDRS (MDS-UPDRS-III values Contrarily Meanwhile addition Conclusion group impairment

In this work we explore some theoretical and practical aspects of one-pot synthesis. The focal point of the study is the preparation of the thiazole heterocycle, with an emphasis on theoretical aspects of the organic and medicinal chemistry of this important privileged structure. The entire set of experimental procedures and characterization steps explored in this work has the potential to assist in the training and/or technical improvement of undergraduate students, and contribute to the teaching of chemistry in Brazilian higher education. It is worth emphasizing these aspects because the experiments shown in the proposed practices involve simple, rapid, low-risk, and low-cost procedures, making it perfectly feasible to reproduce them in undergraduate classes, even in laboratories with limited material resources. onepot one pot synthesis heterocycle structure andor or students education simple rapid lowrisk, lowrisk low risk, risk low-risk lowcost cost classes resources

ABSTRACT The spatial variability of soil attributes in terraced areas is poorly studied in the semi-arid region. Considering that multivariate analysis enhances the diagnosis of spatial variability from geostatistics, soil attributes were studied in different zones between terrace channels in semi-arid region, more precisely in a retention terrace area in Canindé (Ceará, Brazil). Soil samples (n = 100) were collected at depths of 0.0 - 0.1 and 0.1 - 0.2 m for descriptive and geostatistical analysis. For multivariate analysis, samples from three zones relative to the terrace channel (Upper, Middle, and Lower) in the 0.0 - 0.2 m layer were considered, with 30 replicates. There was spatial dependence of soil attributes in the two layers studied. Near the channel, in the respective layers, there was higher clay content (13.7% and 14.7%) and higher degree of flocculation (61.3% and 71.7%) compared to the other zones. Water-dispersible clay was higher in the Upper zone (6.5% and 7.7% in the respective layers), while the Middle zone showed higher potential acidity in the evaluated layers (4.8 and 4.5 cmolc dm-3, respectively) compared to the other zones. In the multivariate analysis, there were highlights for the higher sum of bases in the Upper zone (18.9 ± 0.8 cmolc dm-3), higher sand content in the Middle zone (72.6 ± 0.6%), lower potential acidity (2.1 ± 0.2 cmolc dm-3) and higher phosphorus content (12.8 ± 3.0 mg kg-1) in the Low zone. The zone above the terrace channel loses mainly clay and requires practices to increase water and nutrient retention. semiarid semi arid region geostatistics Ceará, Ceará (Ceará Brazil. Brazil . Brazil) n 100 00 0 0. 01 1 02 2 Upper, (Upper Lower considered 3 replicates 13.7% 137 13 7 (13.7 14.7% 147 14 61.3% 613 61 (61.3 71.7% 717 71 Waterdispersible Water dispersible 6.5% 65 6 5 (6.5 77 7.7 , layers) 4.8 48 4 8 (4. 45 4. dm3, dm3 dm 3, dm-3 respectively 18.9 189 18 9 (18. 08 72.6 726 72 (72. 0.6%, 06 0.6% 0.6%) 2.1 21 (2. 12.8 128 12 (12. 3. kg1 kg kg-1 10 13.7 (13. 14.7 61.3 (61. 71.7 6.5 (6. 7. (4 dm- 18. (18 72. (72 0.6 2. (2 12. (12 kg- 13. (13 14. 61. (61 71. 6. (6 ( (1 (7

ABSTRACT The aim of this study was to characterise the lignocellulosic fractions of pruning waste from tree species showing potential for furniture production in Acaraú, Ceará. The experiment was conducted in a completely randomised, split-plot design, with the plots corresponding to two water regimes (irrigated for one year and irrigated for three years) and the sub-plots to eight tree species, with three replications. The chemical attributes were determined after seven years. Except for the insoluble lignin content, there was a significant effect from the different species in terms of the chemical properties of the wood. The results for the lignocellulosic fractions show the possibility of developing technological ways of adding value to these waste products, especially considering their lignin content. The different species also showed potential for use in producing cellulose pulp, with the exception of Handroanthus impetiginosus due to its high ash content. The results of this study offer new perspectives for future research into the use of forestry waste. Acaraú Ceará randomised splitplot split plot design years subplots sub replications content wood products pulp

RESUMO Objetivo: Investigar os fatores contextuais associados à qualidade de vida (QV) de crianças brasileiras de zero a 12 anos, em momento de ápice de distanciamento social. Métodos: Estudo observacional, transversal, online, de julho a setembro de 2020, com questionário sobre fatores do contexto familiar associados à QV e Inventário Pediátrico sobre QV — PedsQL™. A análise dos dados foi feita por de regressão logística multinomial. Resultados: A amostra foi de 849 crianças, na maioria da Região Sul (75%), brancas (83%), com desenvolvimento típico (79%), sedentárias (68%), com uso de telas (85%) em tempo >3h/dia (44%). As mães eram as cuidadoras principais (90%). Foram significativamente associadas a escores mais elevados de QV: a condição de saúde típica (odds ratio — OR 2,38; intervalo de confiança de 95% — IC95% 1,60–3,55), o tempo de tela ≤2h/dia (OR 1,62; IC95% 1,17–2,24), o distanciamento social considerado “fácil” (OR 1,67; IC95% 1,20–2,32) e a família afirmar estimular a criança (OR 1,93; IC95% 1,08–3,45). Conclusões: Este estudo mostra que o contexto familiar pode influenciar a QV de crianças, especialmente no período de pandemia e de reorganização do ambiente domiciliar. Objetivo (QV 1 anos Métodos observacional transversal online 2020 PedsQL PedsQL™ multinomial Resultados 84 75%, 75 75% , (75%) 83%, 83 83% (83%) 79%, 79 79% (79%) 68%, 68 68% (68%) 85% 85 (85% 3hdia hdia 3h dia h 44%. 44 44% . (44%) 90%. 90 90% (90%) odds 2,38 238 2 38 95 IC95 IC 1,60–3,55, 160355 1,60–3,55 60 3 55 1,60–3,55) 2hdia 2h 1,62 162 62 1,17–2,24, 117224 1,17–2,24 17 24 1,17–2,24) fácil “fácil 1,67 167 67 1,20–2,32 120232 20 32 1,93 193 93 1,08–3,45. 108345 1,08–3,45 08 45 1,08–3,45) Conclusões domiciliar 202 8 7 (75% (83% (79% 6 (68% (85 4 (44% 9 (90% 2,3 23 IC9 16035 1,60–3,5 5 1,6 16 11722 1,17–2,2 1,20–2,3 12023 1,9 19 10834 1,08–3,4 0 (75 (83 (79 (68 (8 (44 (90 2, 1603 1,60–3, 1, 1172 1,17–2, 1,20–2, 1202 1083 1,08–3, (7 (6 ( (4 (9 160 1,60–3 117 1,17–2 1,20–2 120 108 1,08–3 1,60– 11 1,17– 1,20– 10 1,08– 1,60 1,17 1,20 1,08 1,1 1,2 1,0

ABSTRACT Objective: The aim of this study was to investigate the contextual factors associated with the quality of life (QOL) of Brazilian children aged 0–12 years during the strict period of social isolation. Methods: This observational cross-sectional study was conducted between July and September 2020 using an online questionnaire on QOL-related family factors and the Pediatric Quality of Life Inventory (PedsQL™). Results were analyzed by multinomial logistic regression analysis. Results: The sample had 849 children, mostly from the South Region of Brazil (75%), white (83%), with typical development (79%), sedentary (68%), using screen (85%) for >3 h/day (44%). Their mothers were their main caregivers (90%). The following variables were significantly associated with high scores of QOL: typical health status (OR 2.38; 95%CI 1.60–3.55; screen time ≤2 h/day (OR 1.62; 95%CI 1.17–2.24); social distancing considered as “easy” (OR 1.67; 95%CI 1.20–2.32), and stimulation of the child by the family (OR 1.93; 95%CI 1.08–3.45). Conclusions: This study indicates that the family context can influence children’s QOL, especially during the COVID-19 pandemic and home environment reorganization. Objective QOL (QOL 012 0 12 0–1 isolation Methods crosssectional cross sectional 202 QOLrelated related PedsQL™. PedsQL PedsQL™ . (PedsQL™) analysis 84 75%, 75 75% , (75%) 83%, 83 83% (83%) 79%, 79 79% (79%) 68%, 68 68% (68%) 85% 85 (85% 3 > hday h day 44%. 44 44% (44%) 90%. 90 90% (90%) OR 2.38 238 2 38 95CI CI 95 1.60–3.55 160355 1 60 55 ≤ 1.62 162 62 1.17–2.24 117224 17 24 1.17–2.24) easy “easy 1.67 167 67 1.20–2.32, 120232 1.20–2.32 20 32 1.20–2.32) 1.93 193 93 1.08–3.45. 108345 1.08–3.45 08 45 1.08–3.45) Conclusions childrens s COVID19 COVID 19 COVID-1 reorganization 01 0– (PedsQL™ 8 7 (75% (83% (79% 6 (68% (85 4 (44% 9 (90% 2.3 23 1.60–3.5 16035 5 1.6 16 1.17–2.2 11722 12023 1.20–2.3 1.9 10834 1.08–3.4 COVID1 COVID- (PedsQL (75 (83 (79 (68 (8 (44 (90 2. 1.60–3. 1603 1. 1.17–2. 1172 1202 1.20–2. 1083 1.08–3. (7 (6 ( (4 (9 1.60–3 160 1.17–2 117 120 1.20–2 108 1.08–3 1.60– 1.17– 11 1.20– 10 1.08– 1.60 1.17 1.20 1.08 1.1 1.2 1.0

RESUMO: Este estudo teve como objetivo avaliar o impacto da silagem de ração total de Megathyrsus maximus colhido com 70 cm de altura e concentrado no momento da silagem ou ração total de capim cortado a 70 cm, composta por Megathyrsus maximus colhido com 70 cm de altura (nos Exp. I e III) e silagem de ração total cortada a 130 cm, composta por Megathyrsus maximus colhido com 130 cm de altura e concentrado no momento da silagem ou ração total de Megathyrsus maximus colhido a 130 cm de altura (nos Exp. II e IV), sobre o metabolismo ruminal, a digestibilidade dos nutrientes, e o desempenho e as características de carcaça de cordeiros confinados. Os resultados mostraram que TMRS70 aumentou o pH ruminal no Exp. I, e TMRS130 exibiu maior digestibilidade do extrato etéreo, concentração de propionato e menor razão acético/propionato e pH ruminal em comparação com TMR130 no Exp. II. Nos Exp. III e IV, não houve efeito significativo sobre o desempenho e a qualidade da carcaça. No entanto, no Exp. IV, TMRS130 levou a uma diminuição no consumo de matéria seca e no ganho médio diário, enquanto cordeiros alimentados com TMR130 mostraram uma maior área de olho de lombo. A ensilagem da ração total poderia ser usada como um método de conservação para gramíneas jovens (70 cm) sem prejudicar o desempenho, metabolismo, carcaças e qualidade da carne. No entanto, recomenda-se mais estudos avaliando a análise econômica da alimentação com ensilagem de ração total (70 cm) em vez de ração totalmente misturada como método de conservação de forragem. RESUMO 7 nos Exp 13 IV , IV) nutrientes confinados TMRS TMRS7 TMRS13 etéreo acéticopropionato acético TMR TMR13 entanto diário lombo (7 carne recomendase recomenda se forragem 1 TMRS1 TMR1 (

ABSTRACT: This study assessed the impact of total mixed ration silage of Megathyrsus maximus harvested with 70 cm composed of Megathyrsus maximus harvested at 70 cm in height and concentrate at the time of silage or total mixed ration of grass cut at 70 cm composed of Megathyrsus maximus harvested with 70 cm in height (in Exp. I and III) and total mixed ration silage cut at 130 cm composed of Megathyrsus maximus harvested 130 cm height and concentrate at the time of silage or total mixed ration of Megathyrsus maximus harvested with 130 cm composed of Megathyrsus maximus harvested at 130 cm height (in Exp. II and IV), on rumen metabolism, nutrient digestibility, and the performance and carcass characteristics of feedlot lambs. The results showed that TMRS70 increased ruminal pH in Exp. I and TMRS130 exhibited higher ether extract digestibility, propionic concentration, and lower acetic to propionic ratio and ruminal pH compared to TMR130 in Exp. II. In Exp. III and IV, there was no significant effect on the performance and quality of the carcass. However, in Exp. IV, TMRS130 led to decreased dry matter intake and average daily gain, while lambs fed with TMR130 showed a higher rib-eye area. Total ration ensilage could be used as a conservation method for young grasses (70 cm) without impairing performance, metabolism, carcasses, and meat quality. However, further research is recommended to evaluate the economic analysis of feeding total ration ensilage (70 cm) instead of total mixed ration as a forage conservation method. ABSTRACT 7 Exp 13 IV , IV) metabolism digestibility TMRS TMRS7 TMRS13 concentration TMR TMR13 However gain ribeye rib eye area (7 carcasses 1 TMRS1 TMR1 (

RESUMO: O objetivo deste estudo foi obter informações sobre a morfologia externa e interna do canal alimentar da principal praga das brássicas, Plutella xylostella L. (Lepidoptera: Plutellidae), quando exposta a uma formulação microencapsulada do extrato da semente de Annona muricata L. (Annonaceae). A toxicidade da formulação microencapsulada das lagartas alimentadas por 12, 24 e 48 horas mais o controle foi avaliada para verificar alterações morfológicas externas e internas causadas pelo extrato que possam ter causado a morte das lagartas. Após os ensaios, o canal alimentar das lagartas foi dissecado, fixado, desidratado, bloqueado, cortado e colorido. Em seguida, lâminas histológicas foram produzidas e estudadas em microscopia óptica e microscopia de varredura (MEV). A formulação microencapsulada de A. muricata, causou danos irreversíveis ao canal alimentar de P. xylostella, com desorganização, estratificação celular e modificações na morfologia das células consideradas essenciais para a sobrevivência. Na análise por MEV, verificou-se que a membrana peritrófica e a camada muscular permaneceram intactas durante todos os ensaios. Os efeitos foram mais graves com mais horas de exposição. Esses resultados demonstraram que após contato por ingestão, o inseto morre por intoxicação e desorganização celular, inibindo sua capacidade de continuar se alimentando. RESUMO brássicas L Lepidoptera (Lepidoptera Plutellidae, Plutellidae , Plutellidae) Annonaceae. Annonaceae . (Annonaceae) 12 2 4 ensaios dissecado fixado desidratado bloqueado colorido seguida MEV. MEV (MEV) P sobrevivência verificouse verificou exposição ingestão alimentando (Annonaceae 1 (MEV

ABSTRACT: This study obtained information about the external and internal morphology of the alimentary canal of the main pest of brassica, Plutella xylostella L. (Lepidoptera: Plutellidae), when it is exposed to a microencapsulated formulation of the seed extract of Annona muricata L. (Annonaceae). The toxicity of the microencapsulated formulation of the caterpillars fed for 12, 24, and 48 hours plus the control was evaluated to verify and evaluate external and internal morphological changes caused by the extract that may have killed the caterpillars. After the assays, the alimentary canal of the caterpillars was dissected, fixed, dehydrated, blocked, cut, and colored. Then, histological slides were produced and studied under light microscopy and scanning microscopy (SEM). The microencapsulated formulation of A. muricata caused irreversible damage to the alimentary canal of P. xylostella, with disorganization, cell stratification, and modifications in the morphology of the cells considered essential for survival. SEM verified that the peritrophic membrane and the muscular layer remained intact during all the assays. The effects were more severe with more hours of exposure. These results demonstrated that after contact by ingestion, the insect dies due to intoxication and cellular disorganization, inhibiting its ability to continue feeding. ABSTRACT brassica L Lepidoptera (Lepidoptera Plutellidae, Plutellidae , Plutellidae) Annonaceae. Annonaceae . (Annonaceae) 12 24 4 assays dissected fixed dehydrated blocked cut colored Then SEM. (SEM) A P disorganization stratification survival exposure ingestion feeding (Annonaceae 1 2 (SEM

ABSTRACT A bibliometric study was undertaken to analyze the spatiotemporal distribution of works related to managing boron (B) in Eucalyptus spp. from 1970 to 2022. This analysis was based on the Web of Science and Scopus databases, and 121 documents were retrieved. The eight main aspects analyzed were (1) annual scientific production, (2) most relevant research sources, (3) world scientific production, (4) association between countries, (5) most relevant affiliations, (6) indexed terms, (7) most relevant authors, and (8) most cited documents. The results indicated that publications of studies about B in eucalyptus have increased significantly over the last decade (2010-2020). Brazil has produced the most studies relating to the nutritional management of B in eucalyptus, as is mainly reflected in the numbers of researchers, research institutions, and journals that have published on the subject. Our study found that most works have been developed regionally, with little international collaboration between countries although researchers from the United States are the most frequent partners in international collaborations. The majority of the articles analyzed focused on studying the influence of B doses on the growth and rooting of eucalyptus seedlings. Finally, one significant gap in the literature is the need for studies on sources of B via soil and leaves, and new studies on this subject should be commissioned. Thus, the bibliometric review was an efficient approach for observing the main advances in managing B in eucalyptus in recent decades and identifying the leading research groups and future opportunities for scientific advances in this area. (B spp 197 2022 databases 12 retrieved 1 (1 production 2 (2 3 (3 4 (4 5 (5 affiliations 6 (6 terms 7 (7 authors 8 (8 20102020. 20102020 2010 2020 . (2010-2020) institutions regionally collaborations seedlings Finally leaves commissioned Thus area 19 202 ( 2010202 201 (2010-2020 20 201020 (2010-202 20102 (2010-20 (2010-2 (2010- (2010 (201 (20

ABSTRACT Objective: To reveal the capabilities of the Teleinterconsulting application in Stomatology, shedding light on how this tool operates within our own experience. Material and Methods: This observational and cross-sectional study was carried out using data obtained from the pilot study of the Teleinterconsulta application in Stomatology in Paraíba, Brazil, from April 2021 to October 2023. A descriptive analysis of the data was carried out, including an analysis of the experiences of the situation. Results: This study involved the participation of 22 dentists who acted as consultants in the application, which already has more than 400 registered dentists who participate in the healthcare network. Conclusion: Teleconsultation in Stomatology can be a powerful tool that can contribute to the early diagnosis of potentially malignant diseases. We anticipate that this brief communication will inspire professionals to adopt and integrate technologies that allow teleconsultation, promoting greater openness to e-health practices. Objective experience Methods crosssectional cross sectional Paraíba Brazil 202 2023 situation Results 2 40 network Conclusion diseases teleconsultation ehealth e health practices 20 4