ABSTRACT Introduction. The ethical debate surrounding euthanasia and abortion is relevant both in the medical and moral spheres. In the Peruvian context, these practices face legal and ethical challenges. Objective. To analyze the attitudes of medical students towards euthanasia and abortion, considering sociodemographic, academic, and religiosity variables. Methods. A descriptive, cross-sectional, and correlational study was conducted with medical students from a private university in Peru. Online questionnaires were administered to assess attitudes towards euthanasia and abortion, as well as religiosity and sociodemographic characteristics. Results. 341 participants were evaluated. Regarding attitudes towards abortion, religiosity (β = 0.314, p < 0.001), female gender (β = -0.243, p < 0.001), clinical/surgical years (β = -0,190, p < 0.001), and employment (β = 0,111, p = 0.026) were associated. As for attitudes towards euthanasia, associations were observed with religiosity (β = -0.234, p < 0.001) and female gender (β = 0.108, p = 0.042). Conclusions. The influence of religiosity and gender on medical students' attitudes towards euthanasia and abortion is highlighted. These findings have implications for medical education and ethical understanding in a context where these practices face legal and social challenges.

RESUMEN Introducción. El debate ético sobre la eutanasia y el aborto es relevante tanto en el ámbito médico como moral. En el contexto peruano, estas prácticas enfrentan desafíos legales y éticos. Objetivo. Analizar las actitudes de los estudiantes de medicina hacia la eutanasia y el aborto, considerando variables sociodemográficas, académicas y de religiosidad. Métodos. Se realizó un estudio descriptivo, transversal y correlacional con estudiantes de medicina de una universidad privada del Perú. Se aplicaron cuestionarios en línea para evaluar las actitudes hacia la eutanasia y el aborto, así como la religiosidad y características sociodemográficas. Resultados. Se evaluó a 341 participantes. Para las actitudes hacia el aborto, se encontró que la religiosidad (β = 0,314, p < 0,001), ser mujer (β = -0,243, p < 0,001), estar en los años clínico/quirúrgicos (β = -0,190, p < 0,001) y el empleo (β = 0,111, p = 0,026) estaban asociados. En cuanto a las actitudes hacia la eutanasia, se observaron asociaciones con la religiosidad (β = -0,234, p < 0,001) y el ser mujer (β = 0,108, p = 0,042). Conclusiones. Se destaca la influencia de la religiosidad y el sexo en las actitudes de los estudiantes de medicina hacia la eutanasia y el aborto. Estos hallazgos tienen implicaciones para la educación médica y la comprensión ética en un contexto donde estas prácticas enfrentan desafíos legales y sociales.

RESUMEN El presente estudio tiene como objetivo determinar la respuesta del estado chileno en cuanto a las políticas y orientaciones ministeriales dirigidas a escolares migrantes, a partir de la COVID-19. Con esta finalidad, se desarrolló una investigación documental de un corpus de diez ejemplares publicados entre los años 2020 y 2023 por el Ministerio de Educación de Chile (MINEDUC). Del análisis temático se derivaron inductivamente dos categorías que apuntan a los ámbitos de la educación escolar. Los resultados develaron que solo 3 orientaciones aluden directamente al estudiantado migrante, pero se limitan a entregar recomendaciones generales.

ABSTRACT The present study aims to determine the response of the Chilean state in terms of ministerial policies and guidelines aimed at migrant schoolchildren, based on COVID-19. To this end, a documentary research of a corpus of ten issues published between 2020 and 2023 by the Chilean Ministry of Education (MINEDUC) was developed. From the thematic analysis, two categories were derived inductively that point to the areas of school education. The results revealed that only 3 guidelines refer directly to migrant students, but they are limited to providing general recommendations.

Abstract: Introduction: COVID-19 has caused many deaths on the planet. To date we do not know its long-term impact. Conversion of hospital centers and home reclusion impacted those with a disease. Currently, the presence of pain has been identified as a chronic complication of COVID-19. Objective: To document the impact of COVID-19 on patients with pain and its chronicity. Material and methods: Literature search in the PubMed database for documents that contained the words «COVID», «SARS-CoV», «Pain» in the title. No meta-analyses were identified. We found systematized and documentary reviews on which we based our information. Conclusions: COVID-19 presents chronic pain as a long-term manifestation. It is advisable to generate lines of research aimed at documenting this phenomenon.

Resumen: Introducción: La COVID-19 ha causado muchas muertes en el planeta. A la fecha desconocemos su impacto a largo plazo. La conversión de los centros hospitalarios y el resguardo domiciliario impactaron la atención de los enfermos. Actualmente se ha identificado la presencia de dolor como complicación crónica. Objetivo: Documentar el impacto de la COVID-19 en enfermos con dolor y su cronicidad. Material y métodos: Búsqueda de la literatura en la base de datos PubMed de documentos que en el título presentaran las palabras «COVID», «SARS-CoV», «Pain». No se identificaron metaanálisis. Encontramos revisiones sistematizadas y documentales en las que basamos la información presentada. Conclusiones: La COVID-19 presenta dolor crónico como una manifestación a largo plazo. Es conveniente que se generen líneas de investigación tendientes a documentar este fenómeno.

Abstract The objective is to determine the relationship between the performance of the Mexican banking system and the use of digital technology. The methodology is through the use of the fixed effects panel data model, profit per share was used and related to the increase in technological infrastructure. The result shows that the performance of the Mexican banking system is significantly determined by the increase in technological investment, the diversity of technologies used and the Internet connectivity facilities available to the population. It is recommended to identify the new disruptive technologies that will be the basis for the future growth of the banking system. The limitation of the study is that it has focused on the analysis of the impact of technological channels and not traditional channels. The originality is the use of an econometric model to validate the theoretical assertion that digital technologies have been fundamental for the performance of the banking system, in the conclusions it is established that the greater the investment in technologies, the more favorable the growth of the banking system of a country.

Resumen El objetivo es determinar la relación entre el desempeño del sistema bancario mexicano y el uso de la tecnología digital. La metodología es a través del uso del modelo de datos de panel de efectos fijos, se utilizó la utilidad por acción y la relaciona con el incremento de la infraestructura tecnológica. El resultado muestra que el desempeño del sistema bancario mexicano se encuentra significativamente determinada por el incremento de la inversión tecnológica, la diversidad de tecnologías usadas y las facilidades de conectividad de internet disponibles para la población. Se recomienda identificar las nuevas tecnologías disruptivas que serán base del futuro crecimiento del sistema bancario. La limitación del estudio establece que se ha enfocado en el análisis del impacto de los canales tecnológicos y no los canales tradicionales. La originalidad es el uso un modelo econométrico para validar la aseveración teórica de que las tecnologías digitales han sido fundamentales para el desempeño del sistema bancario, en las conclusiones se establecen que entre mayor es la inversión en tecnologías es más favorable el crecimiento del sistema bancario de un país.

RESUMEN Introducción: La Pandemia COVID-19, ha tenido impactos negativos en la salud física y mental de las personas, así como las medidas adoptadas por los gobiernos, para prevenir el contagio masivo de la población como el confinamiento, el aislamiento social, el trabajo y educación virtual. Dentro de los afectados por estos cambios, se encontrarían los estudiantes universitarios del área de la salud, que además de estudiar en estas condiciones de pandemia, no han podido hacer sus prácticas de los servicios de salud. Esta situación de exposición al aislamiento, podría afectar la salud mental de los jóvenes estudiantes universitarios. Objetivo: determinar los niveles de depresión, ansiedad y estrés en estudiantes universitarios y su relación con variables sociodemográficas y las características del aislamiento social durante la Pandemia COVID-19. Métodos: Se realizó un estudio descriptivo, observacional, de corte transversal y cuantitativo, con una muestra de 818 estudiantes universitarios de facultades de ciencias de la salud, mediante el cuestionario autoadministrado DASS-21. Resultados: Los principales hallazgos fueron: una mayor prevalencia en niveles altos (severos y extremadamente severos) en la ansiedad, alcanzado casi a 4 de cada 10 de los evaluados; por otro lado, en depresión y el estrés, 2 de cada 10 de los evaluados, se encontraron en los niveles mencionados. En relación con las variables sociodemográficas, las relacionadas con el COVID-19 y aislamiento social, se hallaron diferencias estadísticamente significativas con el género (mujeres > varones), el haber tenido COVID-19 (Sí > No) y vivir con familiares como antes de la pandemia (Sí > No) obtuvieron en promedio mayores puntajes en depresión, ansiedad y estrés. Conclusión: Los estudiantes que presentaron mayor depresión, ansiedad y estrés con una diferencia significativa fueron de género femenino, con antecedentes de haber tenido Covid-19, menor contacto con familiares y haber cumplido con aislamiento social total.

ABSTRACT Introduction: The COVID-19 Pandemic has had negative impacts on the physical and mental health of people, as well as the measures adopted by governments to prevent the massive contagion of the population, such as confinement, social isolation, virtual work, and virtual education. Among those affected by these changes would be university students in the health area who, in addition to studying in these pandemic conditions, have been unable to do their health service practices. This situation of exposure to isolation could affect the mental health of young university students. Objective: To determine the levels of depression, anxiety, and stress in university students, their relationship with sociodemographic variables, and the characteristics of social isolation during the COVID-19 Pandemic. Methods: A descriptive, observational, cross-sectional, and quantitative study was carried out with a sample of 818 university students from health sciences faculties using the DASS-21 self-administered questionnaire. Results: The main findings were a higher prevalence of high levels (severe and highly severe) in anxiety, reaching almost 4 out of 10 of those evaluated; On the other hand, in depression and stress, 2 out of 10 of those evaluated were found at the mentioned levels. Concerning the sociodemographic variables, those related to COVID-19 and social isolation, statistically significant differences were found with gender (women > men), having had COVID-19 (Yes > No), and living with relatives as before. On average, the pandemic (Yes > No) obtained higher scores in depression, anxiety, and stress. Conclusion: The students who presented greater depression, anxiety, and stress with a significant difference were female, with a history of having had Covid-19, less contact with family members, and having complied with total social isolation

Abstract: The participation of children and adolescents in research requires bioethical measures to safeguard their autonomy and well-being through the application of the informed consent process. Objective: To critically analyze the factors involved in the process of assent/consent in children and adolescents in research. Methodology: Integrative review of scientific evidence carried out between April and June 2023, from manuscripts published between 2014 and 2023 in Web of Science, PubMed, CUIDEN, and CINAHL databases, using the descriptors Process Assessment OR Assent AND Informed Consent AND Bioethics AND Minors OR Child OR Children AND adolescent OR teenage AND Pediatrics AND Research. Twenty primary articles were found, and the results were subjected to content analysis. Result: Three categories were identified: shared consent/assent; child-specific factors for giving assent (age of the child to give assent and autonomy of the child to give assent), and key aspects of the assent process (assent form format; assent form content, and context for applying the assent process). Conclusions: The assent process is a key tool for legal and ethical compliance with the rights of children and adolescents in clinical trial participation. In addition to favoring participation in informed decision-making together with the parents, it is also an instance where the participant’s competencies, capacity for understanding, and autonomy are valued.

Resumen: La incorporación de niñas, niños y adolescentes en investigación requiere de medidas bioéticas para salvaguardar su autonomía y bienestar, a través de la aplicación del proceso de asentimiento informado. Objetivo: Analizar críticamente los factores involucrados en el proceso de asentimiento/consentimiento en niños(as) y adolescentes en la investigación. Metodología: Revisión integrativa de evidencia científica realizada entre abril a junio del 2023, de manuscritos publicados entre los años 2014 y 2023 en bases de datos Web of Science, PubMed, CUIDEN y CINAHL, usando los descriptores Process Assessment OR Assent AND Informed Consent AND Bioethics AND Minors OR Child OR Children AND Adolescent OR Teenage AND Pediatrics AND Research. Se encontraron 20 artículos primarios, cuyos resultados fueron sometidos a un análisis de contenido. Resultado: Se identificaron tres categorías: Consentimiento/asentimiento compartido; Factores propios del niño, niña y adolescente para dar asentimiento (edad del niño, niña y adolescente para dar asentimiento y autonomía del niño, niña y adolescente para dar el asentimiento) y Aspectos claves del proceso de asentimiento (Formato del formulario del asentimiento, Contenido de formulario de asentimiento y Contexto para aplicar el proceso de asentimiento). Conclusiones: El proceso de asentimiento es una herramienta clave para el cumplimiento legal y ético de los derechos de niños y adolescentes en la participación de estudios clínicos. Además de favorecer la participación en la toma de decisiones informada en conjunto con los padres, también, es una instancia donde se valoran sus competencias, capacidad de comprensión y autonomía del participante.

Abstract Nowadays, fungal contamination of medical Cannabis inflorescences during postharvest has become an increasingly frequent and worrisome problem for consumers and the industry in general. This is because some of these microorganisms can produce secondary metabolites, such as mycotoxins, which can be toxic to humans. To assess the risk posed by fungal contamination and evaluate the potential for fungal isolates to produce mycotoxins, samples of medicinal Cannabis were tested for the presence of mycotoxin-forming fungi. Inflorescences were isolated on PDA agar at 23 ± 2 °C for ten days, and the microorganisms were identified. The strain with morphological characteristics compatible with the genus Aspergillus spp. was selected as the fungus with the highest risk of forming hazardous mycotoxins. This isolate was characterized conventionally and by molecular identification using primers for the internal transcribed spacer region (ITS) of ribosomal DNA and different coding genes and was identified as Aspergillus westerdijkiae. To determine mycotoxin formation, the genome of A. westerdijkiae was sequenced using the Illumina Novaseq platform in South Korea. The antiSMASH tool was used to search for gene clusters associated with producing secondary metabolites, and genes related to toxins were manually curated. Regions where the cluster of genes directly involved in OTA biosynthesis (otaA, otaB, otaC, otaR and otaD) were found, suggesting a potential risk of synthesis of this toxin.

Resumen: La incorporación de niñas, niños y adolescentes en investigación requiere de medidas bioéticas para salvaguardar su autonomía y bienestar, a través de la aplicación del proceso de asentimiento informado. Objetivo: Analizar críticamente los factores involucrados en el proceso de asentimiento/consentimiento en niños(as) y adolescentes en la investigación. Metodología: Revisión integrativa de evidencia científica realizada entre abril a junio del 2023, de manuscritos publicados entre los años 2014 y 2023 en bases de datos Web of Science, PubMed, CUIDEN y CINAHL, usando los descriptores Process Assessment OR Assent AND Informed Consent AND Bioethics AND Minors OR Child OR Children AND Adolescent OR Teenage AND Pediatrics AND Research. Se encontraron 20 artículos primarios, cuyos resultados fueron sometidos a un análisis de contenido. Resultado: Se identificaron tres categorías: Consentimiento/asentimiento compartido; Factores propios del niño, niña y adolescente para dar asentimiento (edad del niño, niña y adolescente para dar asentimiento y autonomía del niño, niña y adolescente para dar el asentimiento) y Aspectos claves del proceso de asentimiento (Formato del formulario del asentimiento, Contenido de formulario de asentimiento y Contexto para aplicar el proceso de asentimiento). Conclusiones: El proceso de asentimiento es una herramienta clave para el cumplimiento legal y ético de los derechos de niños y adolescentes en la participación de estudios clínicos. Además de favorecer la participación en la toma de decisiones informada en conjunto con los padres, también, es una instancia donde se valoran sus competencias, capacidad de comprensión y autonomía del participante.

Abstract: The participation of children and adolescents in research requires bioethical measures to safeguard their autonomy and well-being through the application of the informed consent process. Objective: To critically analyze the factors involved in the process of assent/consent in children and adolescents in research. Methodology: Integrative review of scientific evidence carried out between April and June 2023, from manuscripts published between 2014 and 2023 in Web of Science, PubMed, CUIDEN, and CINAHL databases, using the descriptors Process Assessment OR Assent AND Informed Consent AND Bioethics AND Minors OR Child OR Children AND adolescent OR teenage AND Pediatrics AND Research. Twenty primary articles were found, and the results were subjected to content analysis. Result: Three categories were identified: shared consent/assent; child-specific factors for giving assent (age of the child to give assent and autonomy of the child to give assent), and key aspects of the assent process (assent form format; assent form content, and context for applying the assent process). Conclusions: The assent process is a key tool for legal and ethical compliance with the rights of children and adolescents in clinical trial participation. In addition to favoring participation in informed decision-making together with the parents, it is also an instance where the participant’s competencies, capacity for understanding, and autonomy are valued.

Resumen La migración de pueblos indígenas presenta tensiones entre las tradiciones ancestrales y la visión occidental, con implicaciones para la salud pública, particularmente en salud sexual y reproductiva. Este texto tuvo por objetivo analizar las concepciones sobre salud sexual y reproductiva de mujeres indígenas kurripacos de un resguardo del departamento de Guainía (Colombia). Se trata de un estudio de casos en una muestra de 40 mujeres indígenas kurripacos, residentes en el resguardo Paujil, en Guainía, procedentes de distintas comunidades. Se aplicaron entrevistas semiestructuradas construidas con miembros de la misma comunidad y traducidas a lengua nativa. Tres categorías emergieron del análisis: Impacto de la movilidad en las mujeres indígenas; autonomía relativa como marcos de la sexualidad; y concepciones frente al abordaje occidental de la salud sexual y reproductiva. Esta última categoría identificó que los aspectos de la salud sexual y reproductiva como constructo occidental son desconocidos por las participantes, quienes vislumbran formas propias de comprender la salud-enfermedad como parte integrada a todas las dimensiones de la vida/muerte. La interrelación entre las tradiciones ancestrales de los pueblos originarios y el abordaje occidental de la salud exige a profesionales, servicios y sistema un enfoque intercultural que reconozca la autonomía relativa personal y relacional.

Abstract The migration of indigenous peoples presents tensions between ancestral traditions and the western vision, with implications for public health, particularly sexual and reproductive health. To analyze the conceptions of sexual and reproductive health of Kurripaco indigenous women from a reservation in the department of Guainía. Case study in a sample of 40 Kurripaco indigenous women, residents of the Paujil reservation, Guainía, Colombia, from different communities. Semi-structured interviews built with members of the same community and translated into the native language will be applied. Three categories emerged from the analysis: impact of mobility on indigenous women; Relative autonomy as frameworks of sexuality and conceptions against the Western approach to sexual and reproductive health. In this last category, it is found that the aspects of sexual and reproductive health as a Western construct are unknown by the participants, but instead they glimpse their own ways of understanding health-disease as an integrated part of all dimensions of life/death. The interrelationship between the ancestral traditions of native peoples and the western approach to health requires professionals, services, and the system to adopt an intercultural approach that recognizes relative personal and relational autonomy.

Resumo A migração dos povos indígenas apresenta tensões entre as tradições ancestrais e a visão ocidental com implicações para a saúde pública, especialmente a saúde sexual e reprodutiva. Este texto teve como objetivo analisar as concepções de saúde sexual e reprodutiva de mulheres indígenas curipacas de uma reserva indígena no departamento de Guainía (Colômbia). Trata-se de um estudo de caso, com uma amostra de 40 mulheres indígenas curipacas, residentes na reserva Paujil, em Guainía, provenientes de diferentes comunidades. Foram aplicadas entrevistas semiestruturadas elaboradas com membros da mesma comunidade e traduzidas para a língua curipaca. Três categorias resultaram da análise: impacto da mobilidade de mulheres indígenas; autonomia relativa como estrutura da sexualidade; e concepções da abordagem ocidental da saúde sexual e reprodutiva. Esta última categoria identificou que as participantes não têm conhecimento sobre a saúde sexual e reprodutiva desde o ponto de vista ocidental e vislumbram suas próprias formas de compreender a saúde-doença como parte integrante de todas as dimensões da vida/morte. A inter-relação entre as tradições ancestrais dos povos indígenas e a visão ocidental sobre a saúde requer uma abordagem intercultural de profissionais, serviços e do sistema de saúde para que reconheça a autonomia pessoal e relacional desses povos.

Abstract Introduction The time elapsed from diagnosis to hematopoietic stem cell transplantation (HSCT) is influenced by numerous factors. In Brazil, patients using the public health system are also dependent on the availability of HSCT-specific beds in the hematology ward. Objective and Methods We conducted a cohort study of listed patients who underwent allogeneic HSCT at a Brazilian public hospital to investigate the impact of the waitlist time on post-HSCT survival. Results The median time from diagnosis to HSCT was 19 months (IQR, 10 - 43), of which 6 months (IQR, 3 - 9) were spent on the waitlist. The time on the waitlist for HSCT appeared to influence mainly the survival of adult patients (≥ 18 years), with an increasing risk according to this time (RR, 3.53 and 95%CI, 1.81 - 6.88 for > 3 and ≤ 6 months; RR 5.86 and 95%CI, 3.26 - 10.53 for > 6 and ≤ 12 months, and; RR 4.24 and 95%CI, 2.32 - 7.75 for > 12 months). Conclusion Patients who remained on the waitlist for less than 3 months had the highest survival (median survival, 856 days; IQR, 131 - 1607). The risk of reduced survival was about 6-fold higher (95%CI, 2.8 - 11.5) in patients with malignancies. (HSCT factors Brazil HSCTspecific specific ward postHSCT post 1 IQR (IQR 43, 43 , 43) 9 ≥ ( years, years years) RR, (RR 353 53 3.5 95CI CI 95 95%CI 181 81 1.8 688 88 6.8 586 5 86 5.8 326 26 3.2 1053 10.5 424 4 24 4.2 232 2 32 2.3 775 7 75 7.7 months. . months) 85 days 13 1607. 1607 1607) 6fold fold (95%CI 28 8 2. 11.5 115 11 malignancies 35 3. 1. 68 6. 58 5. 105 10. 42 4. 23 77 7. 160 11. 16

Resumo A migração dos povos indígenas apresenta tensões entre as tradições ancestrais e a visão ocidental com implicações para a saúde pública, especialmente a saúde sexual e reprodutiva. Este texto teve como objetivo analisar as concepções de saúde sexual e reprodutiva de mulheres indígenas curipacas de uma reserva indígena no departamento de Guainía (Colômbia). Trata-se de um estudo de caso, com uma amostra de 40 mulheres indígenas curipacas, residentes na reserva Paujil, em Guainía, provenientes de diferentes comunidades. Foram aplicadas entrevistas semiestruturadas elaboradas com membros da mesma comunidade e traduzidas para a língua curipaca. Três categorias resultaram da análise: impacto da mobilidade de mulheres indígenas; autonomia relativa como estrutura da sexualidade; e concepções da abordagem ocidental da saúde sexual e reprodutiva. Esta última categoria identificou que as participantes não têm conhecimento sobre a saúde sexual e reprodutiva desde o ponto de vista ocidental e vislumbram suas próprias formas de compreender a saúde-doença como parte integrante de todas as dimensões da vida/morte. A inter-relação entre as tradições ancestrais dos povos indígenas e a visão ocidental sobre a saúde requer uma abordagem intercultural de profissionais, serviços e do sistema de saúde para que reconheça a autonomia pessoal e relacional desses povos. pública Colômbia. Colômbia . (Colômbia) Tratase Trata se caso 4 Paujil comunidades curipaca análise sexualidade saúdedoença doença vidamorte vida morte vida/morte interrelação inter relação profissionais (Colômbia

Abstract The migration of indigenous peoples presents tensions between ancestral traditions and the western vision, with implications for public health, particularly sexual and reproductive health. To analyze the conceptions of sexual and reproductive health of Kurripaco indigenous women from a reservation in the department of Guainía. Case study in a sample of 40 Kurripaco indigenous women, residents of the Paujil reservation, Guainía, Colombia, from different communities. Semi-structured interviews built with members of the same community and translated into the native language will be applied. Three categories emerged from the analysis: impact of mobility on indigenous women; Relative autonomy as frameworks of sexuality and conceptions against the Western approach to sexual and reproductive health. In this last category, it is found that the aspects of sexual and reproductive health as a Western construct are unknown by the participants, but instead they glimpse their own ways of understanding health-disease as an integrated part of all dimensions of life/death. The interrelationship between the ancestral traditions of native peoples and the western approach to health requires professionals, services, and the system to adopt an intercultural approach that recognizes relative personal and relational autonomy. vision Guainía 4 Colombia communities Semistructured Semi structured applied analysis category participants healthdisease disease lifedeath life death life/death professionals services

Resumen La migración de pueblos indígenas presenta tensiones entre las tradiciones ancestrales y la visión occidental, con implicaciones para la salud pública, particularmente en salud sexual y reproductiva. Este texto tuvo por objetivo analizar las concepciones sobre salud sexual y reproductiva de mujeres indígenas kurripacos de un resguardo del departamento de Guainía (Colombia). Se trata de un estudio de casos en una muestra de 40 mujeres indígenas kurripacos, residentes en el resguardo Paujil, en Guainía, procedentes de distintas comunidades. Se aplicaron entrevistas semiestructuradas construidas con miembros de la misma comunidad y traducidas a lengua nativa. Tres categorías emergieron del análisis: Impacto de la movilidad en las mujeres indígenas; autonomía relativa como marcos de la sexualidad; y concepciones frente al abordaje occidental de la salud sexual y reproductiva. Esta última categoría identificó que los aspectos de la salud sexual y reproductiva como constructo occidental son desconocidos por las participantes, quienes vislumbran formas propias de comprender la salud-enfermedad como parte integrada a todas las dimensiones de la vida/muerte. La interrelación entre las tradiciones ancestrales de los pueblos originarios y el abordaje occidental de la salud exige a profesionales, servicios y sistema un enfoque intercultural que reconozca la autonomía relativa personal y relacional. pública Colombia. Colombia . (Colombia) 4 Paujil comunidades nativa análisis sexualidad participantes saludenfermedad enfermedad vidamuerte vida muerte vida/muerte profesionales relacional (Colombia

ABSTRACT Purpose: To evaluate exogenous hyaluronic acid (HA) derived from bacterial fermentation through enteral and parenteral routes in ischemic skin flaps induced in rats, using clinical and histological exams; and interleukins (IL) as tissue inflammatory biomarkers. Methods: Sixty-four male adults Wistar rats with ischemic skin flaps on the dorsum were randomized into four groups, based on the treatment protocol: subcutaneous administration of saline solution (0.9%) (GI); oral administration of distilled water (GII); subcutaneous administration of HA (0.3%) (GIII); and oral administration of HA (1%) (GIV). Flaps of all groups were comparable regarding clinical and macroscopic evaluation, histological examination, pro-inflammatory cytokines (IL-1β, IL-6, and tumor necrosis factor-α) and anti-inflammatory cytokine IL-10. Results: A lower percentage of necrosis was identified in flaps treated with subcutaneous administration of HA (0.3%). The pro- and anti-inflammatory cytokines, epidermis thickness, blood vessels, and inflammatory cells showed statistically significant inter-group and intra-group differences (p < 0.05). Conclusions: High molecular HA (1,400 ~ 2,000 kDa) administrated by subcutaneous or oral route exhibited beneficial effects in ischemic skin flaps of rats. However, subcutaneous administration of HA (0.3%) showed better results in terms of the percentage of necrosis and epithelialization. Purpose (HA exams IL (IL biomarkers Methods Sixtyfour Sixty protocol 0.9% 09 0 9 (0.9% GI (GI) GII (GII) 0.3% 03 3 (0.3% GIII (GIII) 1% 1 (1% GIV. GIV . (GIV) evaluation examination proinflammatory pro IL1β, IL1β ILβ 1β, 1β β (IL-1β IL6, IL6 6, 6 IL-6 factorα factor α factor-α antiinflammatory anti IL10. IL10 10. 10 IL-10 Results 0.3%. thickness vessels intergroup inter group intragroup intra p 0.05. 005 0.05 05 0.05) Conclusions 1,400 1400 400 (1,40 2000 2 000 2,00 kDa However epithelialization 0.9 (0.9 (GI (GII 0.3 (0.3 (GIII (1 (GIV IL- IL1 IL-1 00 0.0 1,40 140 40 (1,4 200 2,0 0. (0. ( 1,4 14 4 (1, 20 2, (0 1,

ABSTRACT Telematic violence against women is a problem that with the rise of social networks and the pandemic has gained notoriety, according to Law 5777/16 of Integral Protection of Women is a crime. The objective of the research was to characterize the telematic violence suffered by women and its emotional consequences, in Paraguay 2022, through a quantitative, descriptive, cross-sectional design, with a sample of 459 women, participants in a survey with a Google digital form distributed in social networks, using the Event Impact Scale-EIE. The results were: 18.3% (84) suffered from telematic violence, the average age was 36 years, marital status single (60%), salary higher than the minimum wage (61.9%), from Central (43%) and Capital (39%), with university education (85.7%). The frequency was "sometimes" (54.8%) and the main one via WhatsApp (71.4%) as messages (47.6%). The EIE evidenced severe affectation (50%), consequences in the couple relationship (21.4%) and work (14.3%) were referred. The actions taken were blocking the aggressor (52.3%), not reporting (34.5%) and ignoring the message (30.9%). They also suffered psychological (65.4%), physical (21.4%) and sexual (17.8%) violence; knowledge of Law 5777/16 was low. It is concluded that the phenomenon occurs in approximately 2/10 women, in frequency "sometimes", perpetrated by strangers or contacts, severely affecting the woman, there are those who do not report or ignore the fact, so they also suffer other forms of violence concomitantly and ignorance of Law 5777/16 predominates.

RESUMEN La violencia telemática contra la mujer es un problema que con el auge de las redes sociales y la pandemia ha ganado notoriedad, según la Ley 5777/16 de Protección Integral a las Mujeres es un delito. El objetivo de la investigación fue caracterizar la violencia telemática sufrida por mujeres y sus consecuencias emocionales, en Paraguay año 2022, mediante un diseño cuantitativo, descriptivo, trasversal, con una muestra de 459 mujeres, participantes en una encuesta con un formulario digital de Google distribuido en redes sociales, utilizando la Escala de impacto del evento-EIE. Los resultados fueron: 18,3% (84) padecieron de violencia telemática, de ellas la edad promedio fue 36 años, estado civil solteras (60%), salario mayor al mínimo (61,9%), provenientes de Central (43%) y Capital (39%), con nivel de formación universitario (85,7%). La frecuencia fue “a veces” (54,8%) y la principal vía WhatsApp (71,4%) como mensajes (47,6%). La EIE evidenció afectación severa (50%), consecuencias en la relación de pareja (21,4%) y laborales (14,3%) fueron referidas. Las acciones tomadas fueron el bloqueo del agresor (52,3%), no denunciar (34,5%) e ignorar el mensaje (30,9%). También sufrieron violencia psicológica (65,4%), física (21,4%) y sexual (17,8%); el conocimiento de la Ley 5777/16 fue escaso. Se concluye que el fenómeno se presenta en aproximadamente 2/10 mujeres, en frecuencia “a veces”, perpetrada por desconocidos o contactos, afectando severamente a la mujer, hay quienes no denuncian o ignoran el hecho, así también sufren otras formas de violencia concomitantemente y predomina el desconocimiento de la Ley 5777/16.

Abstract Objective: To know the relationship that exists between Emotional Intelligence and Stressful Life Events in Older Adults. Materials and Methods: Correlational descriptive study, in 95 participants from Chihuahua, Chihuahua, Mexico. A Personal Data Record, the MetaMood Scale and the Stress Inventory in the Life of Older Adults were applied. Results: 64.2% of the participants were females, the events that the elderly experienced the most in the last year were the presence of an injury or illness in the Elderly (67.4%), not being able to carry out activities that they enjoyed a lot (65.3%) and the death of a close family member (63.8%). No significant relationship was found between Emotional Intelligence and Stressful Life Events in Older Adults (rs = -.06, p = .56), however, an analysis was carried out with each one of the events and the results showed that Emotional Intelligence was positively related to the death of a close family member (rs = .65, p = .05), the alteration in the health of a family member (rs = .54, p = .05), not being able to do activities they enjoyed (rs = .54, p = .05). Conclusions: The repeated experience of Stressful Life Events can negatively impact the health of the Elderly, more studies are required to identify how Emotional Intelligence can help the Elderly to face these events.

Resumen Objetivo: Conocer la relación que existe entre la Inteligencia Emocional y los Eventos Estresantes de la Vida en los Adultos Mayores. Materiales y Métodos: Estudio descriptivo correlacional realizado en 95 participantes de Chihuahua, Chihuahua, México. Se aplicó una Cedula de Datos Personales, la Escala de Meta-Estado de Ánimo y el Inventario de Estrés en la Vida de Adultos Mayores. Resultados: El 64.2% de los participantes pertenecieron al sexo femenino, los eventos que más experimentaron los AM en el último año fueron la presencia de una lesión o enfermedad en el Adulto Mayor (67.4%), el no poder realizar actividades que disfrutaba mucho (65.3%) y la muerte de un miembro cercano a la familia (63.8%). No se encontró relación significativa entre la Inteligencia Emocional y los Eventos Estresantes de la Vida en los Adultos Mayores (rs = -.06, p = .56), sin embargo, se realizó en análisis con cada uno de los eventos y los resultados mostraron que la Inteligencia Emocional se relacionó de forma positiva con la muerte de un miembro cercano a la familia (rs = .65, p = .05), la alteración en la salud de algún miembro en la familia (rs = .54, p = .05), el no poder realizar actividades que disfrutaba (rs = .54, p = .05). Conclusiones: La experiencia repetida de los Eventos Estresantes de la Vida pueden impactar de forma negativa la salud del Adulto Mayor, se requiere de más estudios que permitan identificar como la IE puede ayudar al Adulto Mayor a enfrentar estos eventos.

Resumen Introducción: La Rata de Magdalena, Xenomys nelsoni, es un roedor endémico de México, de distribución restringida a las selvas bajas caducifolias densas, en una pequeña región de la costa del Pacífico mexicano. Es una especie poco conocida, catalogada como “En Peligro” de acuerdo con la Unión Internacional para la Conservación de la Naturaleza (IUCN). Este desconocimiento unido a la alta tasa de deforestación de su hábitat hace que su conservación sea prioritaria. Objetivo: Realizar un recuento histórico de los registros depositados en las colecciones científicas, generar mapas de distribución potencial y analizar el estado de conservación de la especie. Método: Los datos de ocurrencia de las especies se obtuvieron de la literatura y bases de datos digitales y se analizaron por décadas. Se utilizaron los programas GARP y MaxEnt para generar los modelos de nicho ecológico. La importancia de las variables en el modelo se estimó mediante un análisis Jackknife. Resultados: A lo largo de 129 años 19 recolectores registraron 69 ejemplares, de los cuales 65 están depositados en siete colecciones internacionales y una nacional. Aunque la especie sólo se ha recolectado en Jalisco y Colima, la distribución potencial de X. nelsoni incluye también el estado de Michoacán. De esta área estimada, sólo el 1.5 % se encuentra dentro de un Área Natural Protegida. Conclusiones: Los resultados de la distribución potencial podrían ser utilizados para verificar la presencia de la especie en lugares donde no ha sido recolectada como el norte de la Reserva de la Biosfera Chamela-Cuixmala y en algunas zonas de la provincia fisiográfica Costas del Sur en el estado de Michoacán. Es necesario incrementar los muestreos en regiones poco estudiadas predichas por el modelo y aumentar el área de protección.

Abstract Introduction: The Magdalena Rat, Xenomys nelsoni, is a rodent endemic to Mexico, whose distribution is restricted to dense tropical dry forests in a small region on the Pacific coast of Mexico. It is a poorly known species categorized as “Endangered” by the International Union for Conservation of Nature (IUCN). This lack of knowledge and the high rates of deforestation of its habitat makes its conservation a priority. Objective: To summarize the historical records deposited in scientific collections, to create potential distribution maps, and to analyze the conservation status of the species. Methods: We obtained species occurrence data from literature and digital databases, analyzing them by the decade. We used GARP and MaxEnt software to generate the ecological niche models. The importance of the variables in the model was estimated using the Jackknife technique. Results: Over 129 years, 19 collectors registered 69 specimens, of which 65 are deposited in one national and seven international collections. Although the species has only been collected in Jalisco and Colima, the potential distribution for X. nelsoni also includes the state of Michoacán. Of this estimated area, only 1.5 % is in a Protected Natural Area. Conclusions: The results of the potential distribution could be used to verify the presence of the species in places where it has not been collected, such as the northern part of the Chamela-Cuixmala Biosphere Reserve and in some areas of the physiographic province Costas del Sur in the state of Michoacán. It is needed to increase samplings in the least studied regions predicted by the model and expand the area of protection.