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au:Torre, Ana Clara

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Consumo infantil de alimentos: ¿relación con el estado nutricional materno?
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Cruz-Della-Torre, Ana Clara da

; Silva-Maciel, Thais da

; Vasconcelos-Bastos-Marques, Débora

; Renata-Pereira-de-Brito, Tábatta

; Braga-Lima, Daniela

Revista Cuidarte

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dec 2022, Volume 13 N. 3 elocation 2038

Abstract: Es En Pt | Text: Es En Pt | PDF: Es | PDF: En | PDF: Pt

Resumen Introducción: La figura materna tiene una fuerte influencia en la salud del niño, el estado nutricional y la formación de los hábitos alimentarios del niño, ya que es la principal cuidadora de su hijo. Objetivo: determinar el estado nutricional de las madres y su asociación con el consumo de alimentos de los niños. Materiales y Métodos: Estudio transversal realizado con 163 binomios madre-hijo menores de 24 meses atendidos en Unidades de Salud de la Familia. Se utilizó un cuestionario para recolectar las variables sociodemográficas y antropométricas de madres e infantes. El estado nutricional de los lactantes se clasificó por el índice de masa corporal por indicador de edad y el diagnóstico del estado nutricional de las madres por el índice de masa corporal. La práctica de alimentación del lactante se analizó utilizando formas de marcadores de consumo de alimentos propuesto por el Ministerio de Salud de Brasil. Resultados: Se observó que el 51,53% de las madres tenían sobrepeso y el 30,06% de los niños tenían sobrepeso, según IMC/Edad. En cuanto al consumo de alimentos infantiles, hubo una marcada presencia de alimentos ultraprocesados. El estado nutricional materno inadecuado se asoció con el consumo de snacks envasados el día anterior a la encuesta (p = 0,002). Conclusión: El perfil materno tiene una gran influencia en el consumo de alimentos del lactante, por lo que es necesario implementar actividades de educación en salud para asesorar a las familias, reforzando la importancia de introducir adecuadamente los alimentos complementarios.

Abstract Introduction: As the primary caregiver of her child, the mother figure has a strong influence on the child's health, nutritional status, and formation of eating habits. Objective: To determine the nutritional status of mothers and its association with children's food consumption. Objective: To determine the nutritional status of mothers and its association with children's food consumption. A cross-sectional study was conducted with 163 mother-child pairs at <24 months of age attended in Family Health Units. Materials and Methods: A questionnaire was used to collect sociodemographic and anthropometric variables of mothers and infants. The nutritional status of the infants was determined using the body mass index by age; the diagnosis of the nutritional status of the mothers was determined by body mass index. Infant feeding practice was evaluated using the Food Intake Markers proposed by the Brazilian Ministry of Health. Results: 51.53% of the mothers were overweight, and 30.06% of the children were overweight, according to BMI/age. In terms of children's food consumption, there was a marked presence of ultra-processed foods. Inadequate maternal nutritional status was associated with consuming packaged snacks the day before the survey (p = 0.002). Conclusion: The maternal profile significantly influences infant food consumption; therefore, it is necessary to implement health education activities to advise families and reinforce the importance of adequately introducing complementary foods.

Resumo Introdujo: A figura materna exerce forte influencia na saúde da crianza, no estado nutricional e na formagáo dos hábitos alimentares da crianza, visto que ela é a principal cuidadora de seu filho. Objetivo: determinar o estado nutricional de máes e sua associagáo com o consumo alimentar de crianzas. Materiais e Métodos: Estudo transversal realizado com 163 duplas máe- filho menores de 24 meses atendidas em Unidades de Saúde da Família. Um questionário foi utilizado para coletar as variáveis sociodemográficas e antropométricas de máes e bebes. O estado nutricional dos lactentes foi classificado pelo índice de massa corporal por indicador de idade e o estado nutricional das máes diagnosticadas pelo índice de massa corporal. A prática de alimentado infantil foi analisada por meio de formulários de marcadores de consumo alimentar propostos pelo Ministério da Saúde do Brasil. Resultados: Observou-se que 51,53% das máes estavam acima do peso e 30,06% das crianzas estavam acima do peso, segundo IMC/ Idade. Em relagáo ao consumo de alimentos infantis, houve presenta marcante de alimentos ultraprocessados. O estado nutricional materno inadequado foi associado ao consumo de salgadinhos embalados no dia anterior a pesquisa (p = 0,002). Conclusao: O perfil materno tem grande influencia no consumo alimentar do lactente, por isso é necessário implementar agóes de educado em saúde para orientar as familias, reforjando a importancia da introdugáo adequada dos alimentos complementares.

https://doi.org/10.15649/cuidarte.2038

Aberraciones cromosómicas y defectos congénitos asociados al onfalocele
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Taboada Lugo, Noel

; Algora Hernández, Ana Esther

; de la Torre Santos, María Elena

; Herrera Martínez, Manuela

; Noche González, Gisela

; Arcas Ermeso, Gretsy

Acta Médica del Centro

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jun 2022, Volume 16 N. 2 Pages 207 - 219

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

ABSTRACT Introduction: omphalocele is one of the most frequent defects of anterior abdominal wall. Objectives: to determine the adjusted prevalence rate and to describe the effectiveness of prenatal diagnostic methods, chromosomal abnormalities and congenital defects most frequently associated with omphalocele. Methods: a retrospective descriptive observational study was carried out in Villa Clara Province between January 2010 and December 2019. Data were obtained from the Cuban registry of congenital malformations. The universe was constituted by the 26 cases diagnosed pre or postnatally with omphalocele. The reference population was 75 397 live newborns and 448 stillbirths during the period. Results: the adjusted prevalence rate was 3.4 per 10 000 births. Prenatal diagnosis was made in 96% of cases, the sensitivity of maternal serum alpha fetoprotein determination was 13.8%, while prenatal ultrasound had a sensitivity of 96%. In 12 of the 26 cases with omphalocele (46%) some other associated major congenital defect was found, the most frequently identified were musculoskeletal (31.8%) and cardiovascular (22.7%). Conclusions: the adjusted prevalence observed was slightly higher than that reported in the literature, which could be due to the inclusion of all cases resulting from gestational interruptions. Ultrasound was the most effective method of prenatal diagnosis. Musculoskeletal and cardiovascular defects were the most frequently associated, especially in cases with chromosomal aneuploidy.

RESUMEN Introducción: el onfalocele es uno de los defectos de la pared abdominal anterior más frecuentes. Objetivos: determinar la tasa de prevalencia ajustada y describir la efectividad de los métodos de diagnóstico prenatal, las aberraciones cromosómicas y los defectos congénitos más frecuentemente asociados al onfalocele. Métodos: se realizó un estudio observacional descriptivo de tipo retrospectivo en la Provincia de Villa Clara entre enero de 2010 y diciembre de 2019. Los datos fueron obtenidos de los Registros cubanos de malformaciones congénitas. El universo quedó constituido por los 26 casos diagnosticados pre o postnatalmente con onfalocele. La población de referencia fueron los 75 397 recién nacidos vivos y los 448 nacidos muertos durante el período. Resultados: la tasa de prevalencia ajustada fue de 3,4 por 10 000 nacimientos. Se diagnosticaron prenatalmente el 96% de los casos, la sensibilidad de la determinación sérica materna de alfa fetoproteína fue de 13,8%, mientras que el ultrasonido prenatal tuvo una sensibilidad de un 96%. En 12 de los 26 casos con onfalocele (46%) se constató algún otro defecto congénito mayor asociado, los que con mayor frecuencia se identificaron fueron los musculoesqueléticos (31,8%) y los cardiovasculares (22,7%). Conclusiones: la prevalencia ajustada observada fue discretamente superior a la informada en la literatura, lo que pudiera deberse a la inclusión de todos los casos producto de las interrupciones de la gestación. El ultrasonido constituyó el método más efectivo de diagnóstico prenatal. Los defectos musculoesqueléticos y cardiovasculares fueron los más frecuentemente asociados, sobre todo en los casos con aneuploidías cromosómicas.

Prevalence of atopic dermatitis in adults
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Angles, Maria Valeria

; Antonietti, Carolina Andrea

; Torre, Ana Clara

; Franzé, Estefanía Juszkiewicz

; Mazzuoccolo, Luis Daniel

; Parisi, Claudio Alberto Salvador

Anais Brasileiros de Dermatologia

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feb 2022, Volume 97 N. 1 Pages 107 - 109

Abstract: En | Text: En | PDF: En

https://doi.org/10.1016/j.abd.2020.10.016

Hand, foot, and mouth disease in adults caused by Coxsackievirus B1-B6
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Di Prinzio, Anama

; Bastard, Dolores Pilar

; Torre, Ana Clara

; Mazzuoccolo, Luis Daniel

Anais Brasileiros de Dermatologia

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2022, Volume 97 N. 3 Pages 321 - 325

Abstract: En | Text: En | PDF: En

Abstract Hand, foot, and mouth disease is a viral rickettsial disease caused by Coxsackievirus A16 and Enterovirus 71 in most cases. It is commonly seen in children under ten years old, who present oral enanthema and a macular, maculopapular, or vesicular rash on their hands and feet. However, an increase in cases caused by other viral serotypes was observed in adults in recent years with various clinical presentations and a troublesome diagnosis. Three cases of hand, foot, and mouth disease are reported to show the clinical variability and diagnostic complexity that this disease may present in adult patients.

https://doi.org/10.1016/j.abd.2021.03.012

Telemedicina: validación de un cuestionario para evaluar la experiencia de los profesionales de la salud
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Sommer, Janine

; Torre, Ana Clara

; Bibiloni, Nuria

; Plazzotta, Fernando

; Vázquez Peña, Fernando

; Terrasa, Sergio Adrián

; Boietti, Bruno

; Bruchanski, Lucila

; Mazzuoccolo, Luis

; Luna, Daniel

Revista Panamericana de Salud Pública

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2022, Volume 46 elocation e173

Abstract: Es En Pt | Text: Es En Pt | PDF: Es | PDF: En | PDF: Pt

RESUMEN Objetivo. El siguiente trabajo tiene como objetivo desarrollar y validar un cuestionario para evaluar la experiencia de los profesionales de la salud con los sistemas de telemedicina. Métodos. A partir de la versión abreviada en español y validada localmente del cuestionario para pacientes desarrollado por Parmanto y col., un grupo de expertos consensuó una versión para evaluar la experiencia de profesionales de la salud que brindan servicios de telemedicina. El comportamiento psicométrico de los ítems se testeó en una primera muestra de 129 profesionales a través de un análisis factorial exploratorio. Luego, se evaluó su comprensibilidad a través de entrevistas cognitivas. Por último, en una nueva muestra de 329 profesionales, se evaluó la validez de constructo del cuestionario mediante un análisis factorial confirmatorio (AFC), y su validez de criterio externo, mediante la evaluación de su puntaje con el de una pregunta de resumen. Resultados. Se obtuvo un cuestionario de 12 ítems con una estructura de dos factores con indicadores de ajuste aceptables, documentada mediante AFC. La fiabilidad, la validez convergente y la validez discriminante fueron apropiadas. La validez de criterio externo mostró resultados óptimos. Conclusiones. El instrumento obtenido cuenta con propiedades psicométricas adecuadas y contribuirá a la evaluación objetiva de la experiencia de los profesionales que realizan telemedicina.

ABSTRACT Objective. This objective of this work is to develop and validate a questionnaire to evaluate health professionals' experience with telemedicine systems. Methods. Based on an abbreviated, locally validated Spanish-language version of the patient questionnaire developed by Parmanto et al., a group of experts developed a version to evaluate the experience of health professionals who provide telemedicine services. The psychometric behavior of the items was tested in an initial sample of 129 professionals, using exploratory factor analysis. The comprehensibility of the items was then assessed through cognitive interviews. Finally, in a new sample of 329 professionals, the construct validity of the questionnaire was evaluated by means of confirmatory factor analysis (CFA); its criteria of external validity were assessed by comparing the score with that of a summary question. Results. A 12-item questionnaire was obtained, with a two-factor structure and acceptable adjustment indicators documented through CFA. Reliability, convergent validity, and discriminant validity were appropriate. The criteria of external validity showed optimal results. Conclusions. The instrument obtained has adequate psychometric properties and will contribute to the objective evaluation of the experience of health professionals who perform telemedicine.

RESUMO Objetivo. Desenvolver e validar um questionário para avaliar a experiência dos profissionais de saúde com os sistemas de telemedicina. Métodos. Com base na versão abreviada em espanhol – e validada localmente – do questionário para pacientes desenvolvido por Parmanto et al., um grupo de especialistas gerou uma versão de consenso para avaliar a experiência de profissionais de saúde que prestam serviços de telemedicina. O comportamento psicométrico dos itens foi testado em uma primeira amostra de 129 profissionais, por meio de análise fatorial exploratória. Em seguida, sua compreensibilidade foi avaliada por meio de entrevistas cognitivas. Por fim, em uma nova amostra de 329 profissionais, avaliou-se a validade de construto do questionário por meio de uma análise fatorial confirmatória (AFC), e sua validade de critério externo, mediante a avaliação de sua pontuação com a de uma pergunta resumo. Resultados. Obteve-se um questionário de 12 itens com estrutura de dois fatores, com indicadores de ajuste aceitáveis, documentados pela AFC. A confiabilidade, a validade convergente e a validade discriminante foram adequadas. A validade de critério externo apresentou ótimos resultados. Conclusões. O instrumento obtido possui propriedades psicométricas adequadas e contribuirá para a avaliação objetiva da experiência dos profissionais que realizam telemedicina.

https://doi.org/10.26633/rpsp.2022.173

Pediatric patients with COVID-19 admitted to intensive care units in Brazil: a prospective multicenter study,
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Prata-Barbosa, Arnaldo

; Lima-Setta, Fernanda

; Santos, Gustavo Rodrigues dos

; Lanziotti, Vanessa Soares

; Castro, Roberta Esteves Vieira de

; Souza, Daniela Carla de

; Raymundo, Carlos Eduardo

; Oliveira, Felipe Rezende Caino de

; Lima, Lucio Flavio Peixoto de

; Tonial, Cristian Tedesco

; Colleti Jr., José

; Bellinat, Ana Paula Novaes

; Lorenzo, Vivian Botelho

; Zeitel, Raquel de Seixas

; Pulcheri, Lucas

; Costa, Fernanda Ciuffo Monte da

; La Torre, Fabíola Peixoto Ferreira

; Figueiredo, Elaine Augusta das Neves

; Silva, Thiago Peres da

; Riveiro, Paula Marins

; Mota, Isabele Coelho Fonseca da

; Brandão, Igor Bromonschenkel

; Azevedo, Zina Maria Almeida de

; Gregory, Simone Camera

; Boedo, Fernanda Raquel Oliveira

; Carvalho, Rosana Novais de

; Castro, Natália Almeida de Arnaldo Silva Rodriguez

; Genu, Daniel Hilário Santos

; Foronda, Flavia Andrea Krepel

; Cunha, Antonio José Ledo A.

; Magalhães-Barbosa, Maria Clara de

Jornal de Pediatria

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dec 2020, Volume 96 N. 5 Pages 582 - 592

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Objetivo: Descrever as características clínicas de crianças e adolescentes internados em unidade de terapia intensiva com COVID-19 confirmada. Método: Estudo prospectivo, multicêntrico, observacional, em 19 unidades de terapia intensiva pediátrica. Foram incluídos pacientes entre um mês e 19 anos, admitidos consecutivamente (março a maio de 2020). As características demográficas, clínico-epidemiológicas, o tratamento e os resultados foram coletados. Os subgrupos foram comparados de acordo com as comorbidades, idade < 1 ano e necessidade de ventilação mecânica invasiva. Um modelo de regressão logística multivariável foi utilizado para preditores de gravidade. Resultados: Setenta e nove pacientes foram incluídos (10 com síndrome inflamatória multi-ssistêmica). Mediana de idade, quatro anos; 54% eram do sexo masculino (síndrome inflamatória multissistêmica, 80%); 41% tinham comorbidades (síndrome inflamatória multissistêmica, 20%). Febre (76%), tosse (51%) e taquipneia (50%) foram comuns nos dois grupos. Sintomas graves egastrointestinais e marcadores inflamatórios mais elevados foram mais frequentes na presença de síndrome inflamatória multissistêmica. Infiltrados intersticiais pulmonares foram comuns em ambos os grupos, mas o derrame pleural foi mais prevalente no grupo com síndrome inflamatória multissistêmica (43% vs. 14%). A ventilação mecânica invasiva foi utilizada em 18% (mediana 7,5 dias); antibióticos, oseltamivir e corticosteroides foram utilizados em 76%, 43% e 23%, respectivamente, mas não a hidroxicloroquina. A mediana do tempo de permanência na unidade de terapia intensiva pediátrica foi de 5 dias; duas mortes ocorreram (3%) no grupo não- síndrome inflamatória multissistêmica. Os pacientes com comorbidades eram mais velhos, e as comorbidades foram independentemente associadas à necessidade de ventilação mecânica invasiva(OR 5,5; IC95%, 1,43-21,12; P 0,01). Conclusões: Nas unidades de terapia intensiva pediátrica brasileiras, a COVID-19 apresentou baixa mortalidade, a idade inferior a um ano não foi associada a um pior prognóstico, os pacientes com síndrome inflamatória multissistêmica apresentaram sintomas mais graves, biomarcadores inflamatórios mais elevados e uma grande predominância no sexo masculino, mas apenas a presença de comorbidades e doenças crônicas foi um preditor independente de gravidade.

Abstract Objective: To describe the clinical characteristics of children and adolescents admitted to intensive care with confirmed COVID-19. Method: Prospective, multicenter, observational study, in 19 pediatric intensive care units. Patients aged 1 month to 19 years admitted consecutively (March-May 2020) were included. Demographic, clinical-epidemiological features, treatment, and outcomes were collected. Subgroups were compared according to comorbidities, age < 1 year, and need for invasive mechanical ventilation. A multivariable logistic regression model was used for predictors of severity. Results: Seventy-nine patients were included (ten with multisystemic inflammatory syndrome). Median age 4 years; 54% male (multisystemic inflammatory syndrome, 80%); 41% had comorbidities (multisystemic inflammatory syndrome, 20%). Fever (76%), cough (51%), and tachypnea (50%) were common in both groups. Severe symptoms, gastrointestinal symptoms, and higher inflammatory markers were more frequent in multisystemic inflammatory syndrome. Interstitial lung infiltrates were common in both groups, but pleural effusion was more prevalent in the multisystemic inflammatory syndrome group (43% vs. 14%). Invasive mechanical ventilation was used in 18% (median 7.5 days); antibiotics, oseltamivir, and corticosteroids were used in 76%, 43%, and 23%, respectively, but not hydroxychloroquine. The median pediatric intensive care unit length-of-stay was five days; there were two deaths (3%) in the non- multisystemic inflammatory syndrome group. Patients with comorbidities were older and comorbidities were independently associated with the need for invasive mechanical ventilation (OR 5.5; 95% CI, 1.43-21.12; p = 0.01). Conclusions: In Brazilian pediatric intensive care units, COVID-19 had low mortality, age less than 1 year was not associated with a worse prognosis, and patients with multisystemic inflammatory syndrome had more severe symptoms, higher inflammatory biomarkers, and a greater predominance of males, but only comorbidities and chronic diseases were independent predictors of severity.

https://doi.org/10.1016/j.jped.2020.07.002 2718 downloads

Acute generalized exanthematous pustulosis with features mimicking toxic epidermal necrolysis secondary to amiodarone,
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Distel, Cheryl

; Bollea Garlatti, María Luz

; Torre, Ana Clara

; Riganti, Julia

Anais Brasileiros de Dermatologia

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aug 2020, Volume 95 N. 4 Pages 540 - 542

Abstract: En | Text: En | PDF: En

https://doi.org/10.1016/j.abd.2019.11.010 245 downloads

Chagas disease reactivation: cutaneous manifestations in a transplanted patient
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Ferraresso, Maria Guillermina

; Torre, Ana Clara

; Piva, Maria Manuela Martínez

; Barcan, Laura

Anais Brasileiros de Dermatologia

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dec 2018, Volume 93 N. 6 Pages 890 - 892

Abstract: En | Text: En | PDF: En

Abstract: Chagas disease is an endemic zoonosis caused by a protozoan agent called Trypanosoma cruzi. It is mainly transmitted by a hematophagous vector, and less frequently by blood transfusion, transplacental and solid organ transplant. In most cases, primary infection is not diagnosed and the disease progresses to a chronic phase. Immunosuppressed patients are a vulnerable population that may present an acute, atypical and severe reactivation of the chronic form of this disease. We hereby report a case of a female patient, who received a renal transplant with immunosuppressive treatment, who was diagnosed with a chagasic hypodermitis secondary to an acute reactivation of a chronic phase of this disease. We describe the clinical features, epidemiological and histopathological findings, treatment and course.

https://doi.org/10.1590/abd1806-4841.20187855 1012 downloads

Bullous pyoderma gangrenosum as a predictor of hematological malignancies
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Vacas, Aldana Soledad

; Bollea-Garlatti, María Luz

; Torre, Ana Clara

; Galimberti, Ricardo Luis

Anais Brasileiros de Dermatologia

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feb 2018, Volume 93 N. 1 Pages 133 - 134

Abstract: En | Text: En | PDF: En

Abstract: Pyoderma gangrenosum may precede, coexist or follow diverse systemic diseases. The bullous variety is usually associated with hematologic disorders. From 31 patients with pyoderma gangrenosum diagnosed in our hospital during 10 years, only 2 presented with the bullous type. One patient had previous diagnosis of chronic myeloid leukemia. Both had fast-progressive, painful lesions, and both showed an excellent response to systemic corticosteroids. In less than 3 months the lesions recurred simultaneously with the progression of chronic myeloid leukemia in one patient and with the initial diagnosis of acute myeloid leukemia in the other one. They died in less than four weeks. These findings emphasize the importance of its timely diagnosis. Cutaneous lesions could be the first predictor of an underlying disease.

https://doi.org/10.1590/abd1806-4841.20187031 1103 downloads

10.

Reactivation of Chagas-Mazza disease during treatment with infliximab
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Vacas, Aldana Soledad

; Gomez-Santana, Leidy Viviana

; Torre, Ana Clara

; Galimberti, Ricardo Luis

Anais Brasileiros de Dermatologia

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dec 2017, Volume 92 N. 6 Pages 899 - 900

Abstract: En | Text: En | PDF: En

https://doi.org/10.1590/abd1806-4841.20177346 826 downloads

11.

Microbiota gastrointestinal aeróbica en niños con trastorno del espectro autista. Estudio preliminar
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Moreno, Xiomara

; Santamaria, Giancarlo

; Sánchez, Roger

; e la Torre, Beatriz

; Garcés, Fátima

; Hernández, Celsy

; Martínez, Clara

; Márquez, Ana

; López, Karolina

Gen

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jul 2015, Volume 69 N. 2 Pages 36 - 44

Abstract: Es En | Text: Es En | PDF: Es | PDF: En

Introducción: la alteración de la microbiota intestinal o Dis- biosis ha sido implicada en los cambios de comportamiento del neurodesarrollo y problemas gastrointestinales en pacientes con trastorno del espectro autista (TEA). Objetivo: evaluar la micro- biota intestinal aeróbica (MGIA) y clasificarla en beneficiosa, transitoria y enteropatógena en niños con TEA en la Unidad de Autismo-Maternidad Concepción Palacios. Pacientes y métodos: desde el 26/02/2015 al 12/05/2015 se estudiaron de forma experimental y prospectiva 39 niños diagnosticados con TEA; en el estudio de la MGIA se utilizaron muestras de heces. Se aplicó una encuesta para recopilar datos epidemiológicos, clínicos y comportamientos del neurodesarrollo. Se propone la clasificación de severidad de la disbiosis en grado I,II,III o ausente para la evaluación de la MGIA. Resultados: Fueron 27 niños (69,23%) y 12 niñas (30,77%), con una edad media de 6,3. Disbiosis 31 (79,5%), Disbiosis ausente 8 (20,5%). Según el grado de disbiosis, 5 (16,13%) Grado I, 7 (22,58%) Grado II, 19 (61,29%) Grado III. Los principales agentes causales de disbiosis fueron Klebsiella spp. 16, Proteus mirabilis 8, Streptococcus sp, 6, Serratia marcensces 5, Candida spp. 4. Dos niños presentaron Campylobacter coli como MGIA patógena. Manifestaciones gastrointestinales: 25,80% dolor abdominal, 16,13% diarrea y 38.7% estreñimiento. Trastornos del neurodesarrollo: 50% aleteos, 34% autoagresión, 61% berrinches, insomnio un 34.3%. Conclusiones: Se hace necesario comparar esta investigación con un grupo de niños sin TEA para confirmar que la presencia de disbiosis como causante de alteración de la MGIA se presenta con más frecuencia en niños con TEA.

Background: altering the intestinal microbiota or Dysbiosis has been implicated in the changes the behavior of neurodevelopmen- tal and gastrointestinal problems in patients with autism spectrum disorder (ASD). Objective: To evaluate aerobic intestinal micro- biota (AMGI) and rank it beneficial, transitory and enteropathogenic in children with ASD, the Autism Unit-Maternidad Concepcion Palacios. Patients and Methods: From 26/02/2015 to 05/12/2015 were studied experimentally and prospectively 39 children diagnosed with ASD; in this study the AMGI stool samples were used. A survey to collect epidemiological, clinical and neurodevelopmental behavior was applied. Severity classification dysbiosis proposed in grade I, II, III or absent for evaluating the AMGI. Results: There were 27 kids (69.23%) and 12 girls (30.77%) with a mean age of 6.3. Dysbiosis 31 (79.5%), Dysbiosis absent eight (20.5%). Depending on the degree of dysbiosis, 5 (16.13%) Grade I, 7 (22.58%) Grade II, 19 (61.29%) Grade III. The main causative agents of dysbiosis were Klebsiella spp. 16, Proteus mirabilis 8, Streptococcus sp. 6, Serratia marcensces 5, Candida spp. 4. Two children presented MGIA pathogenic Campylobacter coli. Gastrointestinal symptoms: 25,80% abdominal pain, 16.13% diarrhea and 38.7% constipation. Neurodevelopmental disorders: 50% flapping, 34% self-harm, 61% tantrums and 34.3% insomnia. Conclusion: It is necessary to compare this research with a group of children without ASD to confirm the presence of dysbiosis to cau- se impaired MGIA occurs most often in children with ASD.

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