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1.
Custo-Efetividade da Oxigenação por Membrana Extracorpórea Venoarterial no Choque Cardiogênico Refratário: Um Estudo na Perspectiva Brasileira CustoEfetividade Custo Efetividade Refratário
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Decker, Sérgio Renato da Rosa
; Wainstein, Rodrigo Vugman
; Scolari, Fernando Luis
; Rosa, Priscila Raupp da
; Schneider, Daniel
; Fogazzi, Debora Vacaro
; Trott, Geraldine
; Wolf, Jonas
; Teixeira, Cassiano
; Rover, Marciane Maria
; Nasi, Luiz Antônio
; Rohde, Luis Eduardo
; Polanczyk, Carisi Anne
; Rosa, Regis Goulart
; Bertoldi, Eduardo Gehling
.
Resumo Fundamento O choque cardiogênico (CC) refratário está associado com altas taxas de mortalidade, e o uso de oxigenação por membrana extracorpórea venoarterial (VA-ECMO, do inglês venoarterial extracorporeal membrane oxygenation) como uma opção terapêutica tem gerado discussões. Nesse sentido, sua custo-efetividade, principalmente em países de baixa e média renda como o Brasil, continua incerto.Objetivos: Conduzir uma análise de custo-efetividade na perspectiva do Sistema Único de Saúde (SUS) para avaliar a custo-efetividade de VA-ECMO combinado com o tratamento padrão em comparação ao tratamento padrão isolado em pacientes adultos com CC refratário. Métodos Acompanhamos uma coorte de pacientes com CC refratário tratados com VA-ECMO em centros de assistência terciária do sul brasileiro. Coletamos dados de desfechos e custos hospitalares. Realizamos uma revisão sistemática para complementar nossos dados e usamos o modelo de Markov para estimar a razão de custo-efetividade incremental (RCEI) por ano de vida ajustado pela qualidade (QALY) e por ano de vida ganho. Resultados Na análise do caso-base, a VA-ECMO gerou uma RCEI de Int$ 37 491 por QALY. Análises de sensibilidade identificaram o custo de internação, o risco relativo de sobrevida, e a sobrevida do grupo submetido à VA-ECMO como principais variáveis influenciando os resultados. A análise de sensibilidade probabilística mostrou um benefício do uso de VA-ECMO, com uma probabilidade de 78% de custo-efetividade no limiar recomendado de disposição a pagar. Conclusões Nosso estudo sugere que, dentro do SUS, VA-ECMO pode ser uma terapia custo-efetiva para o CC refratário. Contudo, a escassez de dados sobre a eficácia e de ensaios clínicos recentes que abordem seus benefícios em subgrupos específicos de pacientes destaca a necessidade de mais pesquisas. Ensaios clínicos rigorosos, incluindo perfis diversos de pacientes, são essenciais para confirmar a custo-efetividade com uso de VA-ECMO e assegurar acesso igualitário a intervenções médicas avançadas dentro dos sistemas de saúde, especialmente em países com desigualdades socioeconômicas como o Brasil. (CC mortalidade VAECMO, VAECMO VA ECMO, ECMO (VA-ECMO oxygenation discussões sentido custoefetividade, custoefetividade efetividade, efetividade Brasil incerto.Objetivos incertoObjetivos incerto Objetivos SUS (SUS brasileiro hospitalares (RCEI QALY (QALY ganho casobase, casobase caso base, base caso-base Int 3 49 internação resultados 78 pagar custoefetiva efetiva Contudo pesquisas rigorosos saúde 4 7
Abstract Background Refractory cardiogenic shock (CS) is associated with high mortality rates, and the use of venoarterial extracorporeal membrane oxygenation (VA-ECMO) as a therapeutic option has generated discussions. Therefore, its cost-effectiveness, especially in low- and middle-income countries like Brazil, remains uncertain.Objectives: To conduct a cost-utility analysis from the Brazilian Unified Health System perspective to assess the cost-effectiveness of VA-ECMO combined with standard care compared to standard care alone in adult refractory CS patients. Methods We followed a cohort of refractory CS patients treated with VA-ECMO in tertiary care centers located in Southern Brazilian. We collected data on hospital outcomes and costs. We conducted a systematic review to supplement our data and utilized a Markov model to estimate incremental cost-effectiveness ratios (ICERs) per quality-adjusted life year (QALY) and per life-year gained. Results In the base-case analysis, VA-ECMO yielded an ICER of Int$ 37,491 per QALY. Sensitivity analyses identified hospitalization cost, relative risk of survival, and VA-ECMO group survival as key drivers of results. Probabilistic sensitivity analysis favored VA-ECMO, with a 78% probability of cost-effectiveness at the recommended willingness-to-pay threshold. Conclusions Our study suggests that, within the Brazilian Health System framework, VA-ECMO may be a cost-effective therapy for refractory CS. However, limited efficacy data and recent trials questioning its benefit in specific patient subsets highlight the need for further research. Rigorous clinical trials, encompassing diverse patient profiles, are essential to confirm cost-effectiveness and ensure equitable access to advanced medical interventions within healthcare systems, particularly in socio-economically diverse countries like Brazil. (CS rates VAECMO VA ECMO (VA-ECMO discussions Therefore costeffectiveness, costeffectiveness cost effectiveness, effectiveness low middleincome middle income Brazil uncertain.Objectives uncertainObjectives uncertain Objectives costutility utility costs ICERs (ICERs qualityadjusted quality adjusted QALY (QALY lifeyear gained basecase base case Int 37491 37 491 37,49 results VAECMO, ECMO, 78 willingnesstopay willingness pay threshold that framework costeffective effective However research profiles systems socioeconomically socio economically 3749 3 49 37,4 7 374 4 37,
2.
Detection of anti-Trypanosoma spp. antibodies in cattle from southern Brazil antiTrypanosoma anti Trypanosoma spp
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Samoel, Gisele Vaz Aguirre
; Fernandes, Fagner D’ambroso
; Roman, Isac Junior
; Rodrigues, Bibiana Teixeira
; Miletti, Luiz Claudio
; Bräunig, Patrícia
; Guerra, Renata Rojas
; Sangioni, Luís Antônio
; Cargnelutti, Juliana Felipetto
; Vogel, Fernanda Silveira Flores
.
Revista Brasileira de Parasitologia Veterinária
- Journal Metrics
Resumo A tripanossomose bovina, causada por Trypanosoma vivax, é uma doença que teve origem na África, e atualmente, afeta bovinos em diversos países da América do Sul, incluindo quase todos os estados brasileiros. Apesar dos relatos de infecção por T. vivax, no sul do Brasil, dados sobre seu status de circulação não estão disponíveis atualmente. Neste estudo, o objetivo foi detectar anticorpos IgG anti-Trypanosoma spp. em bovinos do Rio Grande do Sul e sugerir possíveis áreas de risco de transmissão de T. vivax. Foi analisado um total de 691 amostras de soro de bovinos, das regiões intermediárias do Rio Grande do Sul, usando-se o ensaio de imunofluorescência indireta (IFA). A soroprevalência geral de anticorpos anti-Trypanosoma em bovinos foi de 24,6% (170/691). A taxa de detecção variou de 0 a 37,3%, com uma alta prevalência nas regiões intermediárias de Ijuí (37,3%), Uruguaiana (30,7%) e Passo Fundo (28,9%). Portanto, essas regiões foram sugeridas como possíveis áreas de risco para a tripanossomose bovina, devido à alta soroprevalência. Este é o primeiro estudo sorológico a determinar o status de infecção por Trypanosoma spp., em bovinos do Rio Grande do Sul, fornecendo dados sobre a epidemiologia da tripanossomose no estado. bovina vivax África atualmente brasileiros T Brasil antiTrypanosoma anti spp 69 usandose usando se IFA. IFA . (IFA) 246 24 6 24,6 170/691. 170691 170/691 170 (170/691) 373 37 3 37,3% , (37,3%) 30,7% 307 30 7 (30,7% 28,9%. 289 28,9% 28 9 (28,9%) Portanto estado (IFA 2 24, 17069 170/69 17 (170/691 37,3 (37,3% 30,7 (30,7 28,9 (28,9% 1706 170/6 1 (170/69 37, (37,3 30, (30, 28, (28,9 170/ (170/6 (37, (30 (28, (170/ (37 (3 (28 (170 ( (2 (17 (1
Abstract Bovine trypanosomosis, caused by Trypanosoma vivax, is a disease that originated in Africa and currently affects cattle in several South American countries, including almost all Brazilian states. Despite the reports on T. vivax infection in southern Brazil, data on its circulation status is currently unavailable. In this study, we aimed to detect anti-Trypanosoma spp. IgG antibodies in cattle from Rio Grande do Sul and suggest areas with T. vivax transmission risk. A total of 691 serum samples from cattle in the intermediate regions of Rio Grande do Sul were analyzed using indirect immunofluorescence assay (IFA). The overall seroprevalence of anti-Trypanosoma antibodies in cattle was 24.6% (170/691). The detection rate ranged from 0-37.3%, with a high prevalence in the intermediate regions of Ijuí (37.3%), Uruguaiana (30.7%), and Passo Fundo (28.9%). Thus, these regions were suggested as possible bovine trypanosomosis risk areas due to the high seroprevalence. This is the first serological study to determine Trypanosoma spp. infection status in cattle from Rio Grande do Sul, providing data on the epidemiology of trypanosomosis in the state. countries states T Brazil unavailable antiTrypanosoma anti spp 69 IFA. IFA . (IFA) 246 24 6 24.6 170/691. 170691 170/691 170 (170/691) 037.3%, 0373 0 37.3%, 37 3 0-37.3% 373 37.3% , (37.3%) 30.7%, 307 30.7% 30 7 (30.7%) 28.9%. 289 28.9% 28 9 (28.9%) Thus state (IFA 2 24. 17069 170/69 17 (170/691 037 037.3% 0-37.3 37.3 (37.3% 30.7 (30.7% 28.9 (28.9% 1706 170/6 1 (170/69 03 037.3 0-37. 37. (37.3 30. (30.7 28. (28.9 170/ (170/6 037. 0-37 (37. (30. (28. (170/ 0-3 (37 (30 (28 (170 0- (3 (2 (17 ( (1
3.
The Fernandes Figueira Institute: a century devoted to mothers, children, and adolescents Institute mothers children
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4.
Pesquisa e cuidado à saúde no Instituto Fernandes Figueira: depoimento de José Augusto de Britto Figueira
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Resumo O depoimento resulta de entrevista realizada com José Augusto Alves de Britto, médico pediatra que ocupou o cargo de diretor do Instituto Fernandes Figueira entre 2001 e 2008. O relato do depoente aborda diferentes aspectos da história do instituto, como o desenvolvimento da pesquisa e do cuidado à saúde e transformações no cotidiano institucional. O depoimento faz parte de um projeto que documenta e investiga a história do Instituto Fernandes Figueira, que completa seu centenário em 2024. Britto 200 2008 instituto institucional 2024 20 202 2
Abstract This material is the result of an interview with José Augusto Alves de Britto, a physician who served as director of the Fernandes Figueira Institute from 2001 to 2008. It covers different aspects of the history of the institution, such as research development, health care, and transformations in the daily routine there. It is part of a project to document and investigate the history of the Fernandes Figueira Institute, which celebrates its one hundredth anniversary in 2024. Britto 200 2008 institution development care there 2024 20 202 2
5.
Characterisation of an area of coexistent visceral and cutaneous leishmaniasis transmission in the State of Piauí, Brazil Piauí
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Vasconcelos, Silvia Alcântara
; de Sousa, Raimundo Leoberto Torres
; Costa Junior, Enéas
; Diniz e Souza, João Paulo
; Cavalcante, Diane
; da Silva, Antônio Carlos Lima
; de Mendonça, Ivete Lopes
; Mallet, Jacenir
; Teixeira, Clarissa Romero
; Werneck, Guilherme Loureiro
; Araújo-Pereira, Thais
; Pita-Pereira, Daniela
; Britto, Constança
; Vilela, Maurício Luiz
; Gomes, Regis
.
BACKGROUND In Brazil, transmission of visceral and cutaneous leishmaniasis has expanded geographically over the last decades, with both clinical forms occurring simultaneously in the same area. OBJECTIVES This study characterised the clinical, spatial, and temporal distribution, and performed entomological surveillance and natural infection analysis of a leishmaniasis-endemic area. METHODS In order to characterise the risk of leishmaniasis transmission in Altos, Piauí, we described the clinical and socio-demographic variables and the spatial and temporal distribution of cases of American visceral leishmaniasis (AVL) and American cutaneous leishmaniasis (ACL) cases and identified potential phlebotomine vectors. FINDINGS The urban area concentrated almost 54% of ACL and 86.8% of AVL cases. The temporal and spatial distribution of AVL and ACL cases in Altos show a reduction in the number of risk areas, but the presence of permanent disease transmission foci is observed especially in the urban area. 3,808 phlebotomine specimens were captured, with Lutzomyia longipalpis as the most frequent species (98.45%). Of the 35 females assessed for natural infection, one specimen of Lu. longipalpis tested positive for the presence of Leishmania infantum and Leishmania braziliensis DNA. MAIN CONCLUSION Our results indicate the presence of risk areas for ACL and AVL in the municipality of Altos and highlight the importance of entomological surveillance to further understand a possible role of Lu. longipalpis in ACL transmission. Brazil decades leishmaniasisendemic endemic Piauí sociodemographic socio demographic (AVL (ACL vectors 54 868 86 8 86.8 3808 3 808 3,80 captured 98.45%. 9845 98.45% . 98 45 (98.45%) Lu DNA 5 86. 380 80 3,8 984 98.45 9 4 (98.45% 38 3, 98.4 (98.45 98. (98.4 (98. (98 (9 (
6.
Quem controla os controladores no sistema de justiça? A composição dos Conselhos Nacionais da Justiça e do Ministério Público justiça
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Viegas, Rafael Rodrigues
; Loureiro, Maria Rita
; Abrucio, Fernando Luiz
; Teixeira, Marco Antonio Carvalho
; Mongelós, Silvia Avelina Arias
.
RESUMO Introdução: O artigo trata da composição do Conselho Nacional de Justiça (CNJ) e do Conselho Nacional do Ministério Público (CNMP), entre 2005 e 2019. Uma análise dos seus membros é um fator fundamental para explicar o funcionamento desses Conselhos. Materiais e métodos: Realizamos uma prosopografia dos 105 integrantes do CNJ e dos 98 integrantes do CNMP comparando seus respectivos perfis em busca de semelhanças e diferenças. Resultados: A composição de CNJ e CNMP pode ser melhor entendida pela lógica informal do que pelos pelas regras formais de investidura dessas instituições. Por lógica informal compreendemos: i) a política que cruza as instituições judiciárias; ii) as redes acessadas e os critérios que retroalimentam filtros de seleção para as cúpulas do Judiciário e Ministério Público; e iii) os fatores exógenos à institucionalidade dos Conselhos, como pressões de associações de classe. Discussão: O padrão de recrutamento explica a fraca accountability do CNJ e do CNMP, que funcionam segundo o modelo do isomorfismo institucional: embora tenham sido criados para controlar o Judiciário e o Ministério Público, se adaptaram para se moldarem às preferências dos controlados. Introdução (CNJ , (CNMP) 200 2019 Conselhos métodos 10 9 diferenças Resultados compreendemos i judiciárias ii iii classe Discussão institucional controlados (CNMP 20 201 1 2
ABSTRACT Introduction: This article explores the member composition of the National Council of Justice (CNJ) and the National Council of the Public Prosecutor's Office (CNMP) spanning the years 2005 to 2019. Understanding the composition of these Councils is pivotal for grasping their operational mechanisms. Materials and methods: We performed a prosopography of the 105 CNJ members and the 98 CNMP members, comparing their profiles to identify similarities and differences. Results: The composition of the CNJ and the CNMP is more accurately explained by informal dynamics rather than formal appointment rules. These informal dynamics include: i) political influences within judicial institutions; ii) networks and criteria that reinforce selection filters for leadership positions in the Judiciary and Public Prosecutor's Office; and iii) external factors beyond the institutional framework of the Councils, such as pressure from professional associations. Discussion: The recruitment pattern reveals the limited accountability of the CNJ and CNMP, which adhere to an institutional isomorphism model. Despite being tasked with overseeing the Judiciary and the Public Prosecutor's Office, they have adapted to align with the preferences of those they monitor. Introduction (CNJ Prosecutors Prosecutor s (CNMP 200 2019 mechanisms methods 10 9 differences Results rules include i institutions ii iii associations Discussion model monitor 20 201 1 2
7.
PARACANOAGEM NO BRASIL: FINANCIAMENTO E DESENVOLVIMENTO BRASIL
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Maiola, Leonardo
; Santos, Luiz Gustavo Teixeira Fabricio dos
; Baião Junior, Arlindo Antonio
; Duarte, Edison
.
Resumo A paracanoagem é uma das modalidades que foram incluídas nos Jogos Paralímpicos de Verão. O presente estudo teve como objetivo analisar o desenvolvimento financeiro da paracanoagem no Brasil, por meio de uma pesquisa com abordagem qualitativa, de cunho exploratório, descritiva por meio de levantamento bibliográfico e documental. Como resultado foi observado aporte financeiro a atletas e às entidades esportivas durante o ciclo 2012 e 2016, havendo redução nestes incentivos no ciclo 2016 e 2018. Concluímos que houve aumento de recursos após sua inclusão nos Jogos Paralímpicos, porém sem investimentos de recursos privados. Ainda que os resultados demonstram evolução é fundamental entender como foi aplicado o recurso para avaliar a eficiência do investimento. Verão Brasil qualitativa exploratório documental 201 2018 privados investimento 20 2
Abstract Paracanoeing is one of the sports included in the Paralympic Games. The present study aimed to analyze the financial development of paracanoeing in Brazil, through a qualitative research approach, exploratory in nature, descriptive through literature and documentary research. As a result, it was observed a significant financial contribution to athletes and sports entities during the 2012 and 2016 cycles, with a small reduction in these incentives in the 2016 and 2018 cycles. We conclude that there was a significant increase in resources after its inclusion in the Paralympic Games but without private resource investments. Although the results demonstrate evolution, it is essential to understand how the resource was applied to evaluate the efficiency of the investment. Brazil approach nature result 201 cycles investments evolution investment 20 2
Resumen La paracanotaje es una de las modalidades incluidas en los Juegos Paralímpicos. El presente estudio tuvo como objetivo analizar el desarrollo financiero de la paracanotaje en Brasil, a través de una investigación con enfoque cualitativo, de carácter exploratorio, descriptivo a través de una investigación bibliográfica y documental. Como resultado, se observó un gran aporte financiero a los atletas y a las entidades deportivas durante los ciclos 2012 y 2016, habiendo una pequeña reducción en estos incentivos en los ciclos 2016 y 2018. Concluimos que hubo un aumento significativo de recursos después de su inclusión en los Juegos Paralímpicos, pero sin inversiones de recursos privados. Aunque los resultados demuestran evolución, es fundamental entender cómo se aplicó el recurso para evaluar la eficiencia de la inversión. Paralímpicos Brasil cualitativo exploratorio documental resultado 201 2018 privados evolución inversión 20 2
8.
Catálogo Taxonômico da Fauna do Brasil: Setting the baseline knowledge on the animal diversity in Brazil Brasil
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Boeger, Walter A.
; Valim, Michel P.
; Zaher, Hussam
; Rafael, José A.
; Forzza, Rafaela C.
; Percequillo, Alexandre R.
; Serejo, Cristiana S.
; Garraffoni, André R.S.
; Santos, Adalberto J.
; Slipinski, Adam
; Linzmeier, Adelita M.
; Calor, Adolfo R.
; Garda, Adrian A.
; Kury, Adriano B.
; Fernandes, Agatha C.S.
; Agudo-Padrón, Aisur I.
; Akama, Alberto
; Silva Neto, Alberto M. da
; Burbano, Alejandro L.
; Menezes, Aleksandra
; Pereira-Colavite, Alessandre
; Anichtchenko, Alexander
; Lees, Alexander C.
; Bezerra, Alexandra M.R.
; Domahovski, Alexandre C.
; Pimenta, Alexandre D.
; Aleixo, Alexandre L.P.
; Marceniuk, Alexandre P.
; Paula, Alexandre S. de
; Somavilla, Alexandre
; Specht, Alexandre
; Camargo, Alexssandro
; Newton, Alfred F.
; Silva, Aline A.S. da
; Santos, Aline B. dos
; Tassi, Aline D.
; Aragão, Allan C.
; Santos, Allan P.M.
; Migotto, Alvaro E.
; Mendes, Amanda C.
; Cunha, Amanda
; Chagas Júnior, Amazonas
; Sousa, Ana A.T. de
; Pavan, Ana C.
; Almeida, Ana C.S.
; Peronti, Ana L.B.G.
; Henriques-Oliveira, Ana L.
; Prudente, Ana L.
; Tourinho, Ana L.
; Pes, Ana M.O.
; Carmignotto, Ana P.
; Wengrat, Ana P.G. da Silva
; Dornellas, Ana P.S.
; Molin, Anamaria Dal
; Puker, Anderson
; Morandini, André C.
; Ferreira, André da S.
; Martins, André L.
; Esteves, André M.
; Fernandes, André S.
; Roza, André S.
; Köhler, Andreas
; Paladini, Andressa
; Andrade, Andrey J. de
; Pinto, Ângelo P.
; Salles, Anna C. de A.
; Gondim, Anne I.
; Amaral, Antonia C.Z.
; Rondón, Antonio A.A.
; Brescovit, Antonio
; Lofego, Antônio C.
; Marques, Antonio C.
; Macedo, Antonio
; Andriolo, Artur
; Henriques, Augusto L.
; Ferreira Júnior, Augusto L.
; Lima, Aurino F. de
; Barros, Ávyla R. de A.
; Brito, Ayrton do R.
; Romera, Bárbara L.V.
; Vasconcelos, Beatriz M.C. de
; Frable, Benjamin W.
; Santos, Bernardo F.
; Ferraz, Bernardo R.
; Rosa, Brunno B.
; Sampaio, Brunno H.L.
; Bellini, Bruno C.
; Clarkson, Bruno
; Oliveira, Bruno G. de
; Corrêa, Caio C.D.
; Martins, Caleb C.
; Castro-Guedes, Camila F. de
; Souto, Camilla
; Bicho, Carla de L.
; Cunha, Carlo M.
; Barboza, Carlos A. de M.
; Lucena, Carlos A.S. de
; Barreto, Carlos
; Santana, Carlos D.C.M. de
; Agne, Carlos E.Q.
; Mielke, Carlos G.C.
; Caetano, Carlos H.S.
; Flechtmann, Carlos H.W.
; Lamas, Carlos J.E.
; Rocha, Carlos
; Mascarenhas, Carolina S.
; Margaría, Cecilia B.
; Waichert, Cecilia
; Digiani, Celina
; Haddad, Célio F.B.
; Azevedo, Celso O.
; Benetti, Cesar J.
; Santos, Charles M.D. dos
; Bartlett, Charles R.
; Bonvicino, Cibele
; Ribeiro-Costa, Cibele S.
; Santos, Cinthya S.G.
; Justino, Cíntia E.L.
; Canedo, Clarissa
; Bonecker, Claudia C.
; Santos, Cláudia P.
; Carvalho, Claudio J.B. de
; Gonçalves, Clayton C.
; Galvão, Cleber
; Costa, Cleide
; Oliveira, Cléo D.C. de
; Schwertner, Cristiano F.
; Andrade, Cristiano L.
; Pereira, Cristiano M.
; Sampaio, Cristiano
; Dias, Cristina de O.
; Lucena, Daercio A. de A.
; Manfio, Daiara
; Amorim, Dalton de S.
; Queiroz, Dalva L. de
; Queiroz, Dalva L. de
; Colpani, Daniara
; Abbate, Daniel
; Aquino, Daniel A.
; Burckhardt, Daniel
; Cavallari, Daniel C.
; Prado, Daniel de C. Schelesky
; Praciano, Daniel L.
; Basílio, Daniel S.
; Bená, Daniela de C.
; Toledo, Daniela G.P. de
; Takiya, Daniela M.
; Fernandes, Daniell R.R.
; Ament, Danilo C.
; Cordeiro, Danilo P.
; Silva, Darliane E.
; Pollock, Darren A.
; Muniz, David B.
; Gibson, David I.
; Nogueira, David S.
; Marques, Dayse W.A.
; Lucatelli, Débora
; Garcia, Deivys M.A.
; Baêta, Délio
; Ferreira, Denise N.M.
; Rueda-Ramírez, Diana
; Fachin, Diego A.
; Souza, Diego de S.
; Rodrigues, Diego F.
; Pádua, Diego G. de
; Barbosa, Diego N.
; Dolibaina, Diego R.
; Amaral, Diogo C.
; Chandler, Donald S.
; Maccagnan, Douglas H.B.
; Caron, Edilson
; Carvalho, Edrielly
; Adriano, Edson A.
; Abreu Júnior, Edson F. de
; Pereira, Edson H.L.
; Viegas, Eduarda F.G.
; Carneiro, Eduardo
; Colley, Eduardo
; Eizirik, Eduardo
; Santos, Eduardo F. dos
; Shimbori, Eduardo M.
; Suárez-Morales, Eduardo
; Arruda, Eliane P. de
; Chiquito, Elisandra A.
; Lima, Élison F.B.
; Castro, Elizeu B. de
; Orlandin, Elton
; Nascimento, Elynton A. do
; Razzolini, Emanuel
; Gama, Emanuel R.R.
; Araujo, Enilma M. de
; Nishiyama, Eric Y.
; Spiessberger, Erich L.
; Santos, Érika C.L. dos
; Contreras, Eugenia F.
; Galati, Eunice A.B.
; Oliveira Junior, Evaldo C. de
; Gallardo, Fabiana
; Hernandes, Fabio A.
; Lansac-Tôha, Fábio A.
; Pitombo, Fabio B.
; Dario, Fabio Di
; Santos, Fábio L. dos
; Mauro, Fabio
; Nascimento, Fabio O. do
; Olmos, Fabio
; Amaral, Fabio R.
; Schunck, Fabio
; Godoi, Fábio S. P. de
; Machado, Fabrizio M.
; Barbo, Fausto E.
; Agrain, Federico A.
; Ribeiro, Felipe B.
; Moreira, Felipe F.F.
; Barbosa, Felipe F.
; Silva, Fenanda S.
; Cavalcanti, Fernanda F.
; Straube, Fernando C.
; Carbayo, Fernando
; Carvalho Filho, Fernando
; Zanella, Fernando C.V.
; Jacinavicius, Fernando de C.
; Farache, Fernando H.A.
; Leivas, Fernando
; Dias, Fernando M.S.
; Mantellato, Fernando
; Vaz-de-Mello, Fernando Z.
; Gudin, Filipe M.
; Albuquerque, Flávio
; Molina, Flavio B.
; Passos, Flávio D.
; Shockley, Floyd W.
; Pinheiro, Francielly F.
; Mello, Francisco de A.G. de
; Nascimento, Francisco E. de L.
; Franco, Francisco L.
; Oliveira, Francisco L. de
; Melo, Francisco T. de V.
; Quijano, Freddy R.B.
; Salles, Frederico F.
; Biffi, Gabriel
; Queiroz, Gabriel C.
; Bizarro, Gabriel L.
; Hrycyna, Gabriela
; Leviski, Gabriela
; Powell, Gareth S.
; Santos, Geane B. dos
; Morse, Geoffrey E.
; Brown, George
; Mattox, George M.T.
; Zimbrão, Geraldo
; Carvalho, Gervásio S.
; Miranda, Gil F.G.
; Moraes, Gilberto J. de
; Lourido, Gilcélia M.
; Neves, Gilmar P.
; Moreira, Gilson R.P.
; Montingelli, Giovanna G.
; Maurício, Giovanni N.
; Marconato, Gláucia
; Lopez, Guilherme E.L.
; Silva, Guilherme L. da
; Muricy, Guilherme
; Brito, Guilherme R.R.
; Garbino, Guilherme S.T.
; Flores, Gustavo E.
; Graciolli, Gustavo
; Libardi, Gustavo S.
; Proctor, Heather C.
; Gil-Santana, Helcio R.
; Varella, Henrique R.
; Escalona, Hermes E.
; Schmitz, Hermes J.
; Rodrigues, Higor D.D.
; Galvão Filho, Hilton de C.
; Quintino, Hingrid Y.S.
; Pinto, Hudson A.
; Rainho, Hugo L.
; Miyahira, Igor C.
; Gonçalves, Igor de S.
; Martins, Inês X.
; Cardoso, Irene A.
; Oliveira, Ismael B. de
; Franz, Ismael
; Fernandes, Itanna O.
; Golfetti, Ivan F.
; S. Campos-Filho, Ivanklin
; Oliveira, Ivo de S.
; Delabie, Jacques H.C.
; Oliveira, Jader de
; Prando, Jadila S.
; Patton, James L.
; Bitencourt, Jamille de A.
; Silva, Janaina M.
; Santos, Jandir C.
; Arruda, Janine O.
; Valderrama, Jefferson S.
; Dalapicolla, Jeronymo
; Oliveira, Jéssica P.
; Hájek, Jiri
; Morselli, João P.
; Narita, João P.
; Martin, João P.I.
; Grazia, Jocélia
; McHugh, Joe
; Cherem, Jorge J.
; Farias Júnior, José A.S.
; Fernandes, Jose A.M.
; Pacheco, José F.
; Birindelli, José L.O.
; Rezende, José M.
; Avendaño, Jose M.
; Duarte, José M. Barbanti
; Ribeiro, José R. Inácio
; Mermudes, José R.M.
; Pujol-Luz, José R.
; Santos, Josenilson R. dos
; Câmara, Josenir T.
; Teixeira, Joyce A.
; Prado, Joyce R. do
; Botero, Juan P.
; Almeida, Julia C.
; Kohler, Julia
; Gonçalves, Julia P.
; Beneti, Julia S.
; Donahue, Julian P.
; Alvim, Juliana
; Almeida, Juliana C.
; Segadilha, Juliana L.
; Wingert, Juliana M.
; Barbosa, Julianna F.
; Ferrer, Juliano
; Santos, Juliano F. dos
; Kuabara, Kamila M.D.
; Nascimento, Karine B.
; Schoeninger, Karine
; Campião, Karla M.
; Soares, Karla
; Zilch, Kássia
; Barão, Kim R.
; Teixeira, Larissa
; Sousa, Laura D. do N.M. de
; Dumas, Leandro L.
; Vieira, Leandro M.
; Azevedo, Leonardo H.G.
; Carvalho, Leonardo S.
; Souza, Leonardo S. de
; Rocha, Leonardo S.G.
; Bernardi, Leopoldo F.O.
; Vieira, Letícia M.
; Johann, Liana
; Salvatierra, Lidianne
; Oliveira, Livia de M.
; Loureiro, Lourdes M.A. El-moor
; Barreto, Luana B.
; Barros, Luana M.
; Lecci, Lucas
; Camargos, Lucas M. de
; Lima, Lucas R.C.
; Almeida, Lucia M.
; Martins, Luciana R.
; Marinoni, Luciane
; Moura, Luciano de A.
; Lima, Luciano
; Naka, Luciano N.
; Miranda, Lucília S.
; Salik, Lucy M.
; Bezerra, Luis E.A.
; Silveira, Luis F.
; Campos, Luiz A.
; Castro, Luiz A.S. de
; Pinho, Luiz C.
; Silveira, Luiz F.L.
; Iniesta, Luiz F.M.
; Tencatt, Luiz F.C.
; Simone, Luiz R.L.
; Malabarba, Luiz R.
; Cruz, Luiza S. da
; Sekerka, Lukas
; Barros, Lurdiana D.
; Santos, Luziany Q.
; Skoracki, Maciej
; Correia, Maira A.
; Uchoa, Manoel A.
; Andrade, Manuella F.G.
; Hermes, Marcel G.
; Miranda, Marcel S.
; Araújo, Marcel S. de
; Monné, Marcela L.
; Labruna, Marcelo B.
; Santis, Marcelo D. de
; Duarte, Marcelo
; Knoff, Marcelo
; Nogueira, Marcelo
; Britto, Marcelo R. de
; Melo, Marcelo R.S. de
; Carvalho, Marcelo R. de
; Tavares, Marcelo T.
; Kitahara, Marcelo V.
; Justo, Marcia C.N.
; Botelho, Marcia J.C.
; Couri, Márcia S.
; Borges-Martins, Márcio
; Felix, Márcio
; Oliveira, Marcio L. de
; Bologna, Marco A.
; Gottschalk, Marco S.
; Tavares, Marcos D.S.
; Lhano, Marcos G.
; Bevilaqua, Marcus
; Santos, Marcus T.T.
; Domingues, Marcus V.
; Sallum, Maria A.M.
; Digiani, María C.
; Santarém, Maria C.A.
; Nascimento, Maria C. do
; Becerril, María de los A.M.
; Santos, Maria E.A. dos
; Passos, Maria I. da S. dos
; Felippe-Bauer, Maria L.
; Cherman, Mariana A.
; Terossi, Mariana
; Bartz, Marie L.C.
; Barbosa, Marina F. de C.
; Loeb, Marina V.
; Cohn-Haft, Mario
; Cupello, Mario
; Martins, Marlúcia B.
; Christofersen, Martin L.
; Bento, Matheus
; Rocha, Matheus dos S.
; Martins, Maurício L.
; Segura, Melissa O.
; Cardenas, Melissa Q.
; Duarte, Mércia E.
; Ivie, Michael A.
; Mincarone, Michael M.
; Borges, Michela
; Monné, Miguel A.
; Casagrande, Mirna M.
; Fernandez, Monica A.
; Piovesan, Mônica
; Menezes, Naércio A.
; Benaim, Natalia P.
; Reategui, Natália S.
; Pedro, Natan C.
; Pecly, Nathalia H.
; Ferreira Júnior, Nelson
; Silva Júnior, Nelson J. da
; Perioto, Nelson W.
; Hamada, Neusa
; Degallier, Nicolas
; Chao, Ning L.
; Ferla, Noeli J.
; Mielke, Olaf H.H.
; Evangelista, Olivia
; Shibatta, Oscar A.
; Oliveira, Otto M.P.
; Albornoz, Pablo C.L.
; Dellapé, Pablo M.
; Gonçalves, Pablo R.
; Shimabukuro, Paloma H.F.
; Grossi, Paschoal
; Rodrigues, Patrícia E. da S.
; Lima, Patricia O.V.
; Velazco, Paul
; Santos, Paula B. dos
; Araújo, Paula B.
; Silva, Paula K.R.
; Riccardi, Paula R.
; Garcia, Paulo C. de A.
; Passos, Paulo G.H.
; Corgosinho, Paulo H.C.
; Lucinda, Paulo
; Costa, Paulo M.S.
; Alves, Paulo P.
; Roth, Paulo R. de O.
; Coelho, Paulo R.S.
; Duarte, Paulo R.M.
; Carvalho, Pedro F. de
; Gnaspini, Pedro
; Souza-Dias, Pedro G.B.
; Linardi, Pedro M.
; Bartholomay, Pedro R.
; Demite, Peterson R.
; Bulirsch, Petr
; Boll, Piter K.
; Pereira, Rachel M.M.
; Silva, Rafael A.P.F.
; Moura, Rafael B. de
; Boldrini, Rafael
; Silva, Rafaela A. da
; Falaschi, Rafaela L.
; Cordeiro, Ralf T.S.
; Mello, Ramon J.C.L.
; Singer, Randal A.
; Querino, Ranyse B.
; Heleodoro, Raphael A.
; Castilho, Raphael de C.
; Constantino, Reginaldo
; Guedes, Reinaldo C.
; Carrenho, Renan
; Gomes, Renata S.
; Gregorin, Renato
; Machado, Renato J.P.
; Bérnils, Renato S.
; Capellari, Renato S.
; Silva, Ricardo B.
; Kawada, Ricardo
; Dias, Ricardo M.
; Siewert, Ricardo
; Brugnera, Ricaro
; Leschen, Richard A.B.
; Constantin, Robert
; Robbins, Robert
; Pinto, Roberta R.
; Reis, Roberto E. dos
; Ramos, Robson T. da C.
; Cavichioli, Rodney R.
; Barros, Rodolfo C. de
; Caires, Rodrigo A.
; Salvador, Rodrigo B.
; Marques, Rodrigo C.
; Araújo, Rodrigo C.
; Araujo, Rodrigo de O.
; Dios, Rodrigo de V.P.
; Johnsson, Rodrigo
; Feitosa, Rodrigo M.
; Hutchings, Roger W.
; Lara, Rogéria I.R.
; Rossi, Rogério V.
; Gerstmeier, Roland
; Ochoa, Ronald
; Hutchings, Rosa S.G.
; Ale-Rocha, Rosaly
; Rocha, Rosana M. da
; Tidon, Rosana
; Brito, Rosangela
; Pellens, Roseli
; Santos, Sabrina R. dos
; Santos, Sandra D. dos
; Paiva, Sandra V.
; Santos, Sandro
; Oliveira, Sarah S. de
; Costa, Sávio C.
; Gardner, Scott L.
; Leal, Sebastián A. Muñoz
; Aloquio, Sergio
; Bonecker, Sergio L.C.
; Bueno, Sergio L. de S.
; Almeida, Sérgio M. de
; Stampar, Sérgio N.
; Andena, Sérgio R.
; Posso, Sergio R.
; Lima, Sheila P.
; Gadelha, Sian de S.
; Thiengo, Silvana C.
; Cohen, Simone C.
; Brandão, Simone N.
; Rosa, Simone P.
; Ribeiro, Síria L.B.
; Letana, Sócrates D.
; Santos, Sonia B. dos
; Andrade, Sonia C.S.
; Dávila, Stephane
; Vaz, Stéphanie
; Peck, Stewart B.
; Christo, Susete W.
; Cunha, Suzan B.Z.
; Gomes, Suzete R.
; Duarte, Tácio
; Madeira-Ott, Taís
; Marques, Taísa
; Roell, Talita
; Lima, Tarcilla C. de
; Sepulveda, Tatiana A.
; Maria, Tatiana F.
; Ruschel, Tatiana P.
; Rodrigues, Thaiana
; Marinho, Thais A.
; Almeida, Thaís M. de
; Miranda, Thaís P.
; Freitas, Thales R.O.
; Pereira, Thalles P.L.
; Zacca, Thamara
; Pacheco, Thaynara L.
; Martins, Thiago F.
; Alvarenga, Thiago M.
; Carvalho, Thiago R. de
; Polizei, Thiago T.S.
; McElrath, Thomas C.
; Henry, Thomas
; Pikart, Tiago G.
; Porto, Tiago J.
; Krolow, Tiago K.
; Carvalho, Tiago P.
; Lotufo, Tito M. da C.
; Caramaschi, Ulisses
; Pinheiro, Ulisses dos S.
; Pardiñas, Ulyses F.J.
; Maia, Valéria C.
; Tavares, Valeria
; Costa, Valmir A.
; Amaral, Vanessa S. do
; Silva, Vera C.
; Wolff, Vera R. dos S.
; Slobodian, Verônica
; Silva, Vinícius B. da
; Espíndola, Vinicius C.
; Costa-Silva, Vinicius da
; Bertaco, Vinicius de A.
; Padula, Vinícius
; Ferreira, Vinicius S.
; Silva, Vitor C.P. da
; Piacentini, Vítor de Q.
; Sandoval-Gómez, Vivian E.
; Trevine, Vivian
; Sousa, Viviane R.
; Sant’Anna, Vivianne B. de
; Mathis, Wayne N.
; Souza, Wesley de O.
; Colombo, Wesley D.
; Tomaszewska, Wioletta
; Wosiacki, Wolmar B.
; Ovando, Ximena M.C.
; Leite, Yuri L.R.
.
ABSTRACT The limited temporal completeness and taxonomic accuracy of species lists, made available in a traditional manner in scientific publications, has always represented a problem. These lists are invariably limited to a few taxonomic groups and do not represent up-to-date knowledge of all species and classifications. In this context, the Brazilian megadiverse fauna is no exception, and the Catálogo Taxonômico da Fauna do Brasil (CTFB) (http://fauna.jbrj.gov.br/), made public in 2015, represents a database on biodiversity anchored on a list of valid and expertly recognized scientific names of animals in Brazil. The CTFB is updated in near real time by a team of more than 800 specialists. By January 1, 2024, the CTFB compiled 133,691 nominal species, with 125,138 that were considered valid. Most of the valid species were arthropods (82.3%, with more than 102,000 species) and chordates (7.69%, with over 11,000 species). These taxa were followed by a cluster composed of Mollusca (3,567 species), Platyhelminthes (2,292 species), Annelida (1,833 species), and Nematoda (1,447 species). All remaining groups had less than 1,000 species reported in Brazil, with Cnidaria (831 species), Porifera (628 species), Rotifera (606 species), and Bryozoa (520 species) representing those with more than 500 species. Analysis of the CTFB database can facilitate and direct efforts towards the discovery of new species in Brazil, but it is also fundamental in providing the best available list of valid nominal species to users, including those in science, health, conservation efforts, and any initiative involving animals. The importance of the CTFB is evidenced by the elevated number of citations in the scientific literature in diverse areas of biology, law, anthropology, education, forensic science, and veterinary science, among others. publications problem uptodate up date classifications context exception (CTFB http//fauna.jbrj.gov.br/, httpfaunajbrjgovbr http //fauna.jbrj.gov.br/ , jbrj gov br (http://fauna.jbrj.gov.br/) 2015 Brazil 80 specialists 1 2024 133691 133 691 133,69 125138 125 138 125,13 82.3%, 823 82 3 (82.3% 102000 102 000 102,00 7.69%, 769 7 69 (7.69% 11000 11 11,00 . 3,567 3567 567 (3,56 2,292 2292 2 292 (2,29 1,833 1833 833 (1,83 1,447 1447 447 (1,44 1000 1,00 831 (83 628 (62 606 (60 520 (52 50 users science health biology law anthropology education others http//fauna.jbrj.gov.br/ faunajbrjgovbr //fauna.jbrj.gov.br (http://fauna.jbrj.gov.br/ 201 8 202 13369 13 133,6 12513 12 125,1 82.3% (82.3 10200 10 00 102,0 7.69% 76 6 (7.69 1100 11,0 3,56 356 56 (3,5 2,29 229 29 (2,2 1,83 183 83 (1,8 1,44 144 44 (1,4 100 1,0 (8 62 (6 60 52 (5 5 http//fauna.jbrj.gov.br (http://fauna.jbrj.gov.br 20 1336 133, 1251 125, 82.3 (82. 1020 0 102, 7.69 (7.6 110 11, 3,5 35 (3, 2,2 22 (2, 1,8 18 (1, 1,4 14 4 ( 82. (82 7.6 (7. 3, (3 2, (2 (1 7. (7
9.
Estatística Cardiovascular – Brasil 2023 202 20 2
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Oliveira, Gláucia Maria Moraes de
; Brant, Luisa Campos Caldeira
; Polanczyk, Carisi Anne
; Malta, Deborah Carvalho
; Biolo, Andreia
; Nascimento, Bruno Ramos
; Souza, Maria de Fatima Marinho de
; Lorenzo, Andrea Rocha De
; Fagundes Júnior, Antonio Aurélio de Paiva
; Schaan, Beatriz D.
; Silva, Christina Grüne de Souza e
; Castilho, Fábio Morato de
; Cesena, Fernando Henpin Yue
; Soares, Gabriel Porto
; Xavier Junior, Gesner Francisco
; Barreto Filho, Jose Augusto Soares
; Passaglia, Luiz Guilherme
; Pinto Filho, Marcelo Martins
; Machline-Carrion, M. Julia
; Bittencourt, Marcio Sommer
; Pontes Neto, Octavio M.
; Villela, Paolo Blanco
; Teixeira, Renato Azeredo
; Stein, Ricardo
; Sampaio, Roney Orismar
; Gaziano, Thomaz A.
; Perel, Pablo
; Roth, Gregory A.
; Ribeiro, Antonio Luiz Pinho
.
10.
Safety of CoronaVac and ChAdOx1 vaccines against SARS-CoV-2 in patients with rheumatoid arthritis: data from the Brazilian multicentric study safer ChAdOx SARSCoV2 SARSCoV SARS CoV 2 SARS-CoV- arthritis SARS-CoV
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Cruz, Vitor Alves
; Guimarães, Camila
; Rêgo, Jozelia
; Machado, Ketty Lysie Libardi Lira
; Miyamoto, Samira Tatiyama
; Burian, Ana Paula Neves
; Dias, Laiza Hombre
; Pretti, Flavia Zon
; Batista, Danielle Cristina Filgueira Alves
; Mill, José Geraldo
; Oliveira, Yasmin Gurtler Pinheiro de
; Gadelha, Carolina Strauss Estevez
; Gouveia, Maria da Penha Gomes
; Moulin, Anna Carolina Simões
; Souza, Bárbara Oliveira
; Aguiar, Laura Gonçalves Rodrigues
; Vieira, Gabriel Smith Sobral
; Grillo, Luiza Lorenzoni
; Lima, Marina Deorce de
; Pasti, Laís Pizzol
; Surlo, Heitor Filipe
; Faé, Filipe
; Moulaz, Isac Ribeiro
; Macabú, Mariana de Oliveira
; Ribeiro, Priscila Dias Cardoso
; Magalhães, Vanessa de Oliveira
; Aguiar, Mariana Freitas de
; Biegelmeyer, Erika
; Peixoto;, Flávia Maria Matos Melo Campos
; Kayser, Cristiane
; Souza, Alexandre Wagner Silva de
; Castro, Charlles Heldan de Moura
; Ribeiro, Sandra Lúcia Euzébio
; Telles, Camila Maria Paiva França
; Bühring, Juliana
; Lima, Raquel Lima de
; Santos, Sérgio Henrique Oliveira Dos
; Dias, Samuel Elias Basualto
; Melo, Natália Seixas de
; Sanches, Rosely Holanda da Silva
; Boechat, Antonio Luiz
; Sartori, Natália Sarzi
; Hax, Vanessa
; Dória, Lucas Denardi
; Rezende, Rodrigo Poubel Vieira de
; Baptista, Katia Lino
; Fortes, Natália Rodrigues Querido
; Melo, Ana Karla Guedes de
; Melo, Tâmara Santos
; Vieira, Rejane Maria Rodrigues de Abreu
; Vieira, Adah Sophia Rodrigues
; Kakehasi, Adriana Maria
; Tavares, Anna Carolina Faria Moreira Gomes
; Landa, Aline Teixeira de
; Costa, Pollyana Vitoria Thomaz da
; Azevedo, Valderilio Feijó
; Martins-Filho, Olindo Assis
; Peruhype-Magalhães, Vanessa
; Pinheiro, Marcelo de Medeiros
; Monticielo, Odirlei André
; Reis-neto, Edgard Torres Dos
; Ferreira, Gilda Aparecida
; Souza, Viviane Angelina de
; Teixeira-Carvalho, Andréa
; Xavier, Ricardo Machado
; Sato, Emilia Inoue
; Valim, Valeria
; Pileggi, Gecilmara Salviato
; Silva, Nilzio Antonio da
.
Abstract Background Patients with immune-mediated rheumatic diseases (IMRDs) have been prioritized for COVID-19 vaccination to mitigate the infection severity risks. Patients with rheumatoid arthritis (RA) are at a high risk of severe COVID-19 outcomes, especially those under immunosuppression or with associated comorbidities. However, few studies have assessed the safety of the COVID-19 vaccine in patients with RA. Objective To evaluate the safety of vaccines against SARS-CoV-2 in patients with RA. Methods This data are from the study “Safety and Efficacy on COVID-19 Vaccine in Rheumatic Diseases,” a Brazilian multicentric prospective phase IV study to evaluate COVID-19 vaccine in IMRDs in Brazil. Adverse events (AEs) in patients with RA of all centers were assessed after two doses of ChAdOx1 (Oxford/AstraZeneca) or CoronaVac (Sinovac/Butantan). Stratification of postvaccination AEs was performed using a diary, filled out daily and returned at the end of 28 days for each dose. Results A total of 188 patients with RA were include, 90% female. CoronaVac was used in 109 patients and ChAdOx1 in 79. Only mild AEs were observed, mainly after the first dose. The most common AEs after the first dose were pain at the injection (46,7%), headache (39,4%), arthralgia (39,4%), myalgia (30,5%) and fatigue (26,6%), and ChAdOx1 had a higher frequency of pain at the injection (66% vs 32 %, p < 0.001) arthralgia (62% vs 22%, p < 0.001) and myalgia (45% vs 20%, p < 0.001) compared to CoronaVac. The more common AEs after the second dose were pain at the injection (37%), arthralgia (31%), myalgia (23%), headache (21%) and fatigue (18%). Arthralgia (41,4% vs 25%, p = 0.02) and pain at injection (51,4% vs 27%, p = 0.001) were more common with ChAdOx1. No serious AEs were related. With Regard to RA activity level, no significant difference was observed between the three time periods for both COVID-19 vaccines. Conclusion In the comparison between the two immunizers in patients with RA, local reactions and musculoskeletal symptoms were more frequent with ChAdOx1 than with CoronaVac, especially after the first dose. In summary, the AE occurred mainly after the first dose, and were mild, like previous data from others immunizing agents in patients with rheumatoid arthritis. Vaccination did not worsen the degree of disease activity. immunemediated immune mediated (IMRDs COVID19 COVID 19 COVID-1 risks (RA outcomes comorbidities However SARSCoV2 SARSCoV SARS CoV 2 SARS-CoV- Safety Diseases, Diseases Brazil (AEs ChAdOx Oxford/AstraZeneca OxfordAstraZeneca Oxford AstraZeneca (Oxford/AstraZeneca Sinovac/Butantan. SinovacButantan Sinovac/Butantan . Sinovac Butantan (Sinovac/Butantan) diary 18 include 90 female 10 79 46,7%, 467 46,7% , 46 7 (46,7%) 39,4%, 394 39,4% 39 4 (39,4%) 30,5% 305 30 5 (30,5% 26,6%, 266 26,6% 26 6 (26,6%) 66% 66 (66 3 % 0.001 0001 0 001 62% 62 (62 22 22% 45% 45 (45 20 20% 37%, 37 37% (37%) 31%, 31 31% (31%) 23%, 23 23% (23%) 21% 21 (21% 18%. 18% (18%) 41,4% 414 41 (41,4 25 25% 0.02 002 02 51,4% 514 51 (51,4 27 27% related level summary COVID1 1 COVID- SARS-CoV (Sinovac/Butantan 9 46,7 (46,7% 39,4 (39,4% 30,5 (30,5 26,6 (26,6% (6 0.00 000 00 (4 (37% (31% (23% (21 (18% 41,4 (41, 0.0 51,4 (51, 46, (46,7 39, (39,4 30, (30, 26, (26,6 ( (37 (31 (23 (2 (18 41, (41 0. 51, (51 (46, (39, (30 (26, (3 (1 (5 (46 (39 (26
11.
[SciELO Preprints] - Cardiovascular Statistics – Brazil 2023
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Oliveira, Gláucia Maria Moraes de
Brant, Luisa Campos Caldeira
Polanczyk, Carisi Anne
Malta, Deborah Carvalho
Biolo, Andreia
Nascimento, Bruno Ramos
Souza, Maria de Fatima Marinho de
Lorenzo, Andrea Rocha De
Fagundes Júnior, Antonio Aurélio de Paiva
Schaan, Beatriz D.
Silva, Christina Grüne de Souza e
Castilho, Fábio Morato de
Cesena, Fernando Henpin Yue
Soares, Gabriel Porto
Xavier Junior, Gesner Francisco
Barreto-Filho, Jose Augusto Soares
Passaglia, Luiz Guilherme
Pinto-Filho, Marcelo Martins
Machline-Carrion, M. Julia
Bittencourt, Marcio Sommer
Pontes Neto, Octavio M.
Villela, Paolo Blanco
Teixeira, Renato Azeredo
Stein, Ricardo
Sampaio, Roney Orismar
Gaziano, Thomaz A.
Perel, Pablo
Roth, Gregory A.
Ribeiro, Antonio Luiz Pinho
The publication Cardiovascular Statistics – Brazil aims to provide an annual compilation of data and research on the epidemiology of CVDs in Brazil. The report integrates official statistics from the Brazilian Ministry of Health and other governmental entities alongside data from the GBD project, coordinated by the IHME at the University of Washington. Additionally, it incorporates data derived from various sources and scientific studies, including cohorts and registries, that relate to CVDs and their associated risk factors. This publication is intended for a wide range of individuals, including researchers, clinicians, patients, healthcare policymakers, media professionals, the general public, and other interested parties seeking extensive national data about heart disease and stroke. Volunteer researchers from various Brazilian universities and research institutions carry out the project. The group is led by a five-member steering committee (ALPR, CAP, DCM, GMMO, and LCCB). The Brazilian Society of Cardiology fully supports this initiative, and the project receives collaborative support from the GBD Brazil Network and an International Committee (GAR, PP, and TAG) from both the IHME/University of Washington (GAR) and the World Heart Federation (PP and TAG).
A publicação Estatística Cardiovascular – Brasil tem por objetivo fornecer uma compilação anual dos dados e das pesquisas sobre a epidemiologia das DCV no Brasil. Este documento integra as estatísticas oficiais do Ministério da Saúde do Brasil e outras entidades governamentais ao lado de dados do projeto GBD, coordenado pelo IHME da Universidade de Washington. Além disso, incorpora dados derivados de várias fontes e estudos científicos, inclusive coortes e registros, relacionados às DCV e fatores de risco associados. Esta publicação destina-se a um público variado, incluindo pesquisadores, clínicos, pacientes, formuladores de políticas de saúde, profissionais da mídia, o público em geral e todos aqueles que buscam dados nacionais abrangentes sobre DCV e acidente vascular cerebral. Pesquisadores voluntários de várias universidades e instituições de pesquisa brasileiros realizaram este projeto. O grupo é liderado por um comitê diretivo com cinco membros (ALPR, CAP, DCM, GMMO e LCCB). A Sociedade Brasileira de Cardiologia apoia integralmente esta iniciativa e o projeto recebe colaboração da Rede GBD Brasil1 e do GBD International Committee (GAR, PP e TAG) do IHME/Universidade de Washington (GAR) e da World Heart Federation (PP e TAG).
12.
Geophysical key indicators for tailings dam physical integrity monitoring - Brazil
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Sá, Gilvan
; Braga, Marco Antonio
; Almeida, Luiz Antonio Pinto e
; Dias, Leonardo Santana de Oliveira
; Cunha, Alan de Souza
; Rocha, Demetrius Cunha Gonçalves da
; Telles, Ricardo Luiz Teixeira
.
Abstract The geotechnical monitoring of tailings dams combined with a suitable application of geophysical electrical methods can improve their structure evaluation, allowing several correlations between direct analyses and the resistivity anomaly pattern. Considering this synergy, twenty-three electrical resistivity sections (ERT) were acquired along the beach, abutments, and central part of a dam, totalizing 10,776 m of dataset. After the interpretation of each ERT section, comparing the anomaly ranges with the water level meters measurements, three resistivity zones were defined: Zones of low resistivity (<64 ohm-m), correlated to regions of high humidity; zones of high resistivity (> 357 ohm-m), interpreted as dry zones, and regions with intermediate resistivity values, located between these limits. The groundwater surface generated from the interpretation of the electrical resistivity dataset and the groundwater surface acquired from the water level gauges were almost coincident. On the right abutment, the conductive anomalies showed remarkable continuity, suggesting a high moisture content in this region with strong gradients (200 mV) directed towards the zone of low resistivity values identified in the sections. The analysis showed a robust correlation of the ERT data with localized physical geotechnical measurements, valuable for monitoring dam integrity, overseeing the structure's response to climate and operational changes, and ultimately mitigating the risks of failure. The results of this study support the adoption of a seasonal 4D electrical resistivity survey as an effective tool to monitor and manage surface and high humidity zones, key indicators of dam integrity throughout the entire structure. evaluation pattern synergy twentythree twenty (ERT beach abutments 10776 10 776 10,77 section measurements defined <64 64 (<6 ohmm, ohmm ohm , ohm-m) > ( 35 limits coincident abutment continuity 200 (20 mV structures s changes failure D 1077 1 77 10,7 <6 6 (< ohm-m 3 20 (2 107 7 10, < 2
13.
COVID-Inconfidentes - SARS-CoV-2 seroprevalence in two Brazilian urban areas in the fourth quarter 2020: study protocol and initial results
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Meireles, Adriana Lúcia
; Garcia Lourenção, Luciano
; Alves de Menezes Júnior, Luiz Antônio
; Nascimento Coletro, Hillary
; Sousa Justiniano, Irene Carolina
; Silva de Moura, Samara
; Popolino Diniz, Amanda
; da Silva Sabião, Thaís
; Sampaio Rocha, Ana Maria
; Batista, Aline Priscila
; Nunes Lage, Nara
; dos Santos Simões, Bárbara
; Ali Santos, Carolina
; de Deus Mendonça, Raquel
; de Souza Andrade, Amanda Cristina
; Furbino Barbosa, Keila
; Zumerle Masioli, Cássio
; Cardoso Carraro, Júlia Cristina
; Carvalho de Menezes, Mariana
; Rezende Macedo Nascimento, Renata Cristina
; Roever, Leonardo
; Teixeira Caiaffa, Waleska
; Lins Machado Coelho, George Luiz
.
Abstract Objective: To describe study protocol and initial results of research project COVID-Inconfidentes. Method: This paper described the methodological procedures adopted and the prevalence of the SARS-CoV-2 infection in the population. A household survey was conducted between October and December 2020, in two historic cities of Brazil's mining region. Anti-SARS-CoV-2 antibody was detected using the Wondfo® rapid test. The face-to face interview consisted of administration of a questionnaire containing registration data, sociodemographic and economic variables, living habits, general health condition, mental health, sleep habits, and eating and nutrition. Results: We evaluated 1,762 residents, of which 764 (43.4 %) were in Mariana and 998 (56.6 %) in Ouro Preto. For both cities, 51.9 % of the interviewees were female, with a predominance of the age range 35 to 59 years old (47.2 %). The prevalence of the SARS-CoV-2 infection was 5.5 % in both cities, 6.2 % in Ouro Preto, and 4.7 % in Mariana (p-value > 0.05). Conclusion: The study was effective to estimate the seroprevalence of infection by the virus and its findings will enable further analyses of the health conditions of the population related to social isolation and the risk of infection with SARS-CoV-2.
Resumen Describir el protocolo de estudio y los resultados iniciales del proyecto de investigación COVID Inconfidentes. Método: Este artículo describe los procedimientos metodológicos adoptados y la prevalencia de la infección por SARS-CoV-2 en la población. Se realizó una encuesta domiciliaria entre octubre y diciembre de 2020, en dos ciudades históricas de la región minera de Brasil. El anticuerpo anti-SARS-CoV-2 se detectó mediante la prueba rápida Wondfo®. La entrevista cara a cara consistió en la administración de un cuestionario que contenía datos de registro, variables sociodemográficas y económicas, hábitos de vida, estado general de salud, salud mental, hábitos de sueño, alimentación y nutrición. Resultados: Se evaluaron 1.762 habitantes, de los cuales 764 (43,4 %) estaban en Mariana y 998 (56,6 %) en Ouro Preto. Para ambas ciudades, el 51,9 % de los entrevistados eran del sexo femenino, con predominio del rango de edad de 35 a 59 años (47,2 %). La prevalencia de la infección por SARS-CoV-2 fue del 5,5 % en ambos municipios, del 6,2 % en Ouro Preto y del 4,7 % en Mariana (p > 0,05). Conclusión: El estudio fue efectivo para estimar la seroprevalencia de infección por el virus y sus hallazgos permitirán analizar más las condiciones de salud de la población relacionadas con el aislamiento social y el riesgo de infección por SARS-CoV-2.
14.
Association of coffee intake and its polyphenols with mammographic findings in women who visited the Brazilian Public Health Service
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Florencio-de Meneses, Ayana
; de Rezende-Ferreira-Mendes, Ana Luiza
; Rocha, Daianne Cristina
; Alves-de Carvalho-Sampaio, Helena
; Ferreira-Carioca, Antônio Augusto
; Porto-Pinheiro, Luiz Gonzaga
; Diógenes-Vasques, Paulo Henrique
; Nogueira-Bezerra, Ilana
; Teixeira-Cacau, Leandro
.
Abstract Objective: this study aimed to evaluate if there is an association of intake of coffee and its polyphenols with mammographic findings in women treated at a breast care service unit of the Unified Health System (SUS), Brazil. Research methods and procedures: this was a cross-sectional study with 532 women treated at a health service. The participants were divided according to their mammographic reports into two groups: without and with altered findings. Two 24-h dietary recalls were applied and coffee consumption was categorized into three groups (less than 1 cup, 1 to 3 cups, and more than 3 cups). Phenolic acids were determined using the Phenol Explorer program. The intake of polyphenols was calculated by adding the values obtained from the total amount of coffee consumed during the day. The Multiple Source Method (MSM) was applied to analyze the usual intake. Results: of the 532 women, 178 (33.5 %) had altered mammographic findings. The participants' average daily coffee intake was 193.4 mL. No significant association was found between coffee consumption and mammographic findings. However, it was found that the second tertile of polyphenols was a protective factor for breast changes. Conclusion: coffee polyphenols are protective against breast changes in the group evaluated and, thus, can help prevent breast cancer.
Resumen Objetivo: este estudio tuvo como objetivo evaluar si existe una asociación de la ingesta de café y sus polifenoles con los hallazgos mamográficos de mujeres tratadas en una unidad de patología mamaria del Sistema Unificado de Salud (SUS), Brasil. Métodos y procedimientos de investigación: este fue un estudio transversal con 532 mujeres tratadas en un servicio de salud. Las participantes se dividieron de acuerdo con sus informes mamográficos en dos grupos: sin y con hallazgos alterados. Se aplicaron dos registros dietéticos de 24 horas y el consumo de café se clasificó en tres grupos (menos de 1 taza, 1 a 3 tazas y más de 3 tazas). Los ácidos fenólicos se determinaron utilizando el programa Phenol Explorer. La ingesta de polifenoles se calculó sumando los valores obtenidos de la cantidad total de café consumido durante el día. Se aplicó el método de fuentes múltiples (MSM) para analizar la ingesta habitual. Resultados: de las 532 mujeres, 178 (33,5 %) tenían hallazgos mamográficos alterados. La ingesta diaria promedio de café de los participantes fue de 193,4 ml. No se encontró una asociación significativa entre el consumo de café y los hallazgos mamográficos. Sin embargo, se encontró que el segundo tercil de polifenoles era un factor protector para los cambios mamarios. Conclusión: los polifenoles del café son protectores contra los cambios mamarios en el grupo evaluado y, por lo tanto, podrían ayudar a prevenir el cáncer de mama.
15.
O trabalho terceirizado e por turnos está associado ao aumento do risco de COVID-19? Descobertas de um estudo com trabalhadores da mineração COVID19 COVID 19 COVID-19 COVID1 1 COVID-1 COVID-
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Menezes-Júnior, Luiz Antônio Alves
; Parajára, Magda do Carmo
; Silva, Juliana Ilídio
; Friche, Amélia Augusta de Lima
; Andrade, Amanda Cristina de Souza
; Silva, Luiz Sergio
; Machado, Elaine Leandro
; Freitas, Silvia Nascimento
; Caiaffa, Waleska Teixeira
; Meireles, Adriana Lúcia
.
Resumo Objetivos: investigar os fatores de risco sociodemográficos e ocupacionais associados à infeção por COVID-19 em trabalhadores da mineração. Métodos: estudo de coorte retrospectivo com dados secundários dos trabalhadores de uma empresa multinacional de mineração, de março de 2020 a abril de 2021. Casos de COVID-19 foram definidos por meio do resultado do teste reação em cadeia da polimerase (PCR) positivo para SARS-CoV-2. Riscos relativos (RR) para testes positivos foram obtidos por regressão de Poisson. Resultados: dos 10.484 trabalhadores testados, 2.578 (24,6%) tiveram pelo menos um resultado positivo. Foi realizada uma média de 4,0 (desvio-padrão: 3,6) testes para cada trabalhador, totalizando 41.962 testes. A maioria dos trabalhadores eram do sexo masculino (88,3%), com idade entre 30 e 39 anos (38,7%), terceirizados (74,1%) e que não trabalhavam em turnos (70,5%). No modelo múltiplo, os trabalhadores terceirizados (RR: 1,39; intervalo de confiança de 95% [IC95%]: 1,27;1,51) e trabalhadores por turnos (RR: 1,10; IC95%: 1,01;1,20) apresentavam maior risco de infecção quando comparados com seus homólogos. Conclusões: os trabalhadores terceirizados e por turnos exibiram maior risco de infecção pelo SARS-CoV-2 quando comparados com seus homólogos. Portanto, é necessário fornecer monitoramento contínuo com oferta regular e adequada de testes para mitigação e prevenção da COVID-19 nestes grupos ocupacionais. Objetivos COVID19 COVID 19 COVID-1 mineração Métodos 202 2021 PCR (PCR SARSCoV2. SARSCoV2 SARSCoV SARS CoV 2. 2 RR (RR Poisson Resultados 10484 10 484 10.48 testados 2578 578 2.57 24,6% 246 24 6 (24,6% 40 4 0 4, desviopadrão desvio padrão (desvio-padrão 3,6 36 3 trabalhador 41962 41 962 41.96 88,3%, 883 88,3% , 88 (88,3%) 38,7%, 387 38,7% 38 7 (38,7%) 74,1% 741 74 1 (74,1% 70,5%. 705 70,5% . 70 5 (70,5%) múltiplo 1,39 139 95 IC95% IC95 IC [IC95%] 1,271,51 127151 1,27 1,51 27 51 1,27;1,51 1,10 110 1,011,20 101120 1,01 1,20 01 20 1,01;1,20 homólogos Conclusões SARS-CoV- Portanto COVID1 COVID- 1048 48 10.4 257 57 2.5 24,6 (24,6 3, 4196 96 41.9 88,3 8 (88,3% 38,7 (38,7% 74,1 (74,1 70,5 (70,5% 1,3 13 9 IC9 [IC95% 271 1,271,5 12715 127 1,2 151 1,5 1,27;1,5 1,1 11 011 1,011,2 10112 101 1,0 120 1,01;1,2 SARS-CoV 104 10. 25 24, (24, 419 41. 88, (88,3 38, (38,7 74, (74, 70, (70,5 1, [IC95 1,271, 1271 12 15 1,27;1, 1,011, 1011 1,01;1, (24 (88, (38, (74 (70, [IC9 1,271 1,27;1 1,011 1,01;1 (2 (88 (38 (7 (70 [IC 1,27; 1,01; ( (8 (3
Abstract Objectives: to investigate the sociodemographic and occupational risk factors associated with COVID-19 infection in mining workers. Methods: a retrospective cohort study, using secondary workers’ health data from a multinational mining company, from March 2020 to April 2021. A COVID-19 case was defined based on a SARS-CoV-2 positive result in a polymerase chain reaction (PCR) test. Risk ratios (RRs) for positive testing were estimated using Poisson’s regression model. Results: of 10,484 workers, 2,578 (24.6%) had at least one positive result for COVID-19. Each worker underwent an average of 4.0 (standard deviation: 3.6) tests, totaling 41,962 PCR tests. Most of the evaluated workers were male (88.3%), aged from 30 to 39 years (38.7%), outsourced (74.1%) and non-shift workers (70.5%). Our multivariate model showed that outsourced (RR: 1.39; 95% confidence interval [95%CI]: 1.27;1.51) and shift workers (RR: 1.10; 95%CI: 1.01;1.20) had a higher risk of SARS-CoV-2 infection than their counterparts. Conclusions: outsourced and shift workers have a higher risk of COVID-19 infection than their counterparts. Therefore, it is necessary to provide continuous monitoring with regular and adequate testing for mitigation and prevention of COVID-19 in these occupational groups. Objectives COVID19 COVID 19 COVID-1 Methods study company 202 2021 SARSCoV2 SARSCoV SARS CoV 2 SARS-CoV- (PCR test RRs (RRs Poissons Poisson s Results 10484 10 484 10,48 2578 578 2,57 24.6% 246 24 6 (24.6% COVID19. 19. 40 4 0 4. standard deviation 3.6 36 3 tests 41962 41 962 41,96 88.3%, 883 88.3% , 88 (88.3%) 38.7%, 387 38.7% 38 7 (38.7%) 74.1% 741 74 1 (74.1% nonshift non 70.5%. 705 70.5% . 70 5 (70.5%) RR (RR 1.39 139 95 95%CI 95CI CI [95%CI] 1.271.51 127151 1.27 1.51 27 51 1.27;1.51 1.10 110 1.011.20 101120 1.01 1.20 01 20 1.01;1.20 counterparts Conclusions Therefore groups COVID1 COVID- SARS-CoV 1048 48 10,4 257 57 2,5 24.6 (24.6 3. 4196 96 41,9 88.3 8 (88.3% 38.7 (38.7% 74.1 (74.1 70.5 (70.5% 1.3 13 9 [95%CI 271 1.271.5 12715 127 1.2 151 1.5 1.27;1.5 1.1 11 011 1.011.2 10112 101 1.0 120 1.01;1.2 104 10, 25 2, 24. (24. 419 41, 88. (88.3 38. (38.7 74. (74. 70. (70.5 1. 1.271. 1271 12 15 1.27;1. 1.011. 1011 1.01;1. (24 (88. (38. (74 (70. 1.271 1.27;1 1.011 1.01;1 (2 (88 (38 (7 (70 1.27; 1.01; ( (8 (3
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