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Abstract Background Patients with immune-mediated rheumatic diseases (IMRDs) have been prioritized for COVID-19 vaccination to mitigate the infection severity risks. Patients with rheumatoid arthritis (RA) are at a high risk of severe COVID-19 outcomes, especially those under immunosuppression or with associated comorbidities. However, few studies have assessed the safety of the COVID-19 vaccine in patients with RA. Objective To evaluate the safety of vaccines against SARS-CoV-2 in patients with RA. Methods This data are from the study “Safety and Efficacy on COVID-19 Vaccine in Rheumatic Diseases,” a Brazilian multicentric prospective phase IV study to evaluate COVID-19 vaccine in IMRDs in Brazil. Adverse events (AEs) in patients with RA of all centers were assessed after two doses of ChAdOx1 (Oxford/AstraZeneca) or CoronaVac (Sinovac/Butantan). Stratification of postvaccination AEs was performed using a diary, filled out daily and returned at the end of 28 days for each dose. Results A total of 188 patients with RA were include, 90% female. CoronaVac was used in 109 patients and ChAdOx1 in 79. Only mild AEs were observed, mainly after the first dose. The most common AEs after the first dose were pain at the injection (46,7%), headache (39,4%), arthralgia (39,4%), myalgia (30,5%) and fatigue (26,6%), and ChAdOx1 had a higher frequency of pain at the injection (66% vs 32 %, p < 0.001) arthralgia (62% vs 22%, p < 0.001) and myalgia (45% vs 20%, p < 0.001) compared to CoronaVac. The more common AEs after the second dose were pain at the injection (37%), arthralgia (31%), myalgia (23%), headache (21%) and fatigue (18%). Arthralgia (41,4% vs 25%, p = 0.02) and pain at injection (51,4% vs 27%, p = 0.001) were more common with ChAdOx1. No serious AEs were related. With Regard to RA activity level, no significant difference was observed between the three time periods for both COVID-19 vaccines. Conclusion In the comparison between the two immunizers in patients with RA, local reactions and musculoskeletal symptoms were more frequent with ChAdOx1 than with CoronaVac, especially after the first dose. In summary, the AE occurred mainly after the first dose, and were mild, like previous data from others immunizing agents in patients with rheumatoid arthritis. Vaccination did not worsen the degree of disease activity. immunemediated immune mediated (IMRDs COVID19 COVID 19 COVID-1 risks (RA outcomes comorbidities However SARSCoV2 SARSCoV SARS CoV 2 SARS-CoV- Safety Diseases, Diseases Brazil (AEs ChAdOx Oxford/AstraZeneca OxfordAstraZeneca Oxford AstraZeneca (Oxford/AstraZeneca Sinovac/Butantan. SinovacButantan Sinovac/Butantan . Sinovac Butantan (Sinovac/Butantan) diary 18 include 90 female 10 79 46,7%, 467 46,7% , 46 7 (46,7%) 39,4%, 394 39,4% 39 4 (39,4%) 30,5% 305 30 5 (30,5% 26,6%, 266 26,6% 26 6 (26,6%) 66% 66 (66 3 % 0.001 0001 0 001 62% 62 (62 22 22% 45% 45 (45 20 20% 37%, 37 37% (37%) 31%, 31 31% (31%) 23%, 23 23% (23%) 21% 21 (21% 18%. 18% (18%) 41,4% 414 41 (41,4 25 25% 0.02 002 02 51,4% 514 51 (51,4 27 27% related level summary COVID1 1 COVID- SARS-CoV (Sinovac/Butantan 9 46,7 (46,7% 39,4 (39,4% 30,5 (30,5 26,6 (26,6% (6 0.00 000 00 (4 (37% (31% (23% (21 (18% 41,4 (41, 0.0 51,4 (51, 46, (46,7 39, (39,4 30, (30, 26, (26,6 ( (37 (31 (23 (2 (18 41, (41 0. 51, (51 (46, (39, (30 (26, (3 (1 (5 (46 (39 (26

https://doi.org/10.1186/s42358-024-00397-5

Multicriteria analysis model for foot-and-mouth disease risk classification in the state of Goiás - Brazil footandmouth foot and mouth
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Bosso, Fernando Borges

; Jayme, Valéria de Sá

; Teixeira, Weslen Fabrício Pires

; Souza, Guilherme Rocha Lino de

Ciência Rural

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2023, Volume 53 N. 11 elocation e20220669

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO: A febre aftosa (FA) é uma doença viral, febril, aguda e altamente contagiosa que afeta várias espécies domésticas e silvestres. Sua ocorrência resulta em grandes impactos negativos na cadeia pecuária e na economia de um país ou região. A FA está presente na América do Sul desde o fim do século XIX gerando esforços de órgãos oficiais no combate à enfermidade com vistas à erradicação, o que possibilitará futuramente a retirada da vacina, fato previsto no estado de Goiás para o ano de 2021. Neste sentido, o presente estudo objetivou classificar o risco de ocorrência de FA nos rebanhos do estado de Goiás. Para tanto, avaliou-se e combinou-se vários fatores de risco (FR) ligados à introdução e disseminação da FA obtidos de dados de 126.345 propriedades rurais. Estes FR foram agrupados em módulos formados por caminhos de introdução e disseminação da FA. A combinação dos FR se deu por meio de adição, sendo em seguida ponderados por pesos atribuídos por especialistas. Foram gerados os escores de introdução e disseminação de FA em Goiás, possibilitando a classificação do risco de ocorrência da doença no estado. Identificou-se que a maioria do rebanho e do território goiano se encontra em baixos níveis de risco. Foi identificada complexa composição nos níveis de risco obtidos, indicando ampla variação dos fatores que compuseram os escores de risco, especialmente nos municípios de mais alto escore de ocorrência. Variáveis ligadas à densidade de rebanho e trânsito e movimentação de animais apresentaram importante participação na composição dos escores. Acreditamos que os resultados deste trabalho podem compor uma ferramenta importante na tomada de decisão sobre as ações e estratégias de combate à FA em Goiás, ao passo que posteriores avaliações e adaptações poderão ser realizadas para a validação do modelo proposto. RESUMO (FA viral febril silvestres região erradicação vacina 2021 sentido tanto avaliouse avaliou combinouse combinou (FR 126345 126 345 126.34 rurais adição especialistas Identificouse Identificou proposto 202 12634 12 34 126.3 20 1263 1 3 126. 2

ABSTRACT: Foot-and-mouth disease (FMD) is a viral disease that affects several animal species, including domestic and wildlife ones. The occurrence of an FMD outbreak can potentially cause a large negative impact on countries or regions’ livestock production and economy. Performed over several decades, mass herd vaccination has been the main strategy to control the disease. However, countries are beginning the stage of eradicating FMD, which involves suspending vaccinations. The present study carried out a risk classification for FMD occurrence in Goiás State, Brazil by evaluating and combining multiple risk factors involved in FMD introduction and dissemination. Data from 126,345 rural properties were collected and categorized by municipality. The risk factors were grouped into two modules and then scores for each module were obtained by adding and weighting the risk factors. These combined scores resulted in the final FMD occurrence risk score. Most of the municipalities, as well as the herds were found in the lowest likelihood levels. Variables linked to herd density and animal movement played a key role in the score composition. We believed that this model can be a useful tool in the decision-making process regarding actions and strategies related to FMD eradication. ABSTRACT Footandmouth Foot mouth (FMD species ones regions economy decades However vaccinations State dissemination 126345 126 345 126,34 municipality municipalities levels composition decisionmaking decision making eradication 12634 12 34 126,3 1263 1 3 126,

https://doi.org/10.1590/0103-8478cr20220669

Telemonitoramento da Insuficiência Cardíaca – A Experiência de um Centro
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Cruz, Isabel O.

; Costa, Susana

; Teixeira, Rogério

; Franco, Fátima

; Gonçalves, Lino

Arquivos Brasileiros de Cardiologia

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mar 2022, Volume 118 N. 3 Pages 599 - 604

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Fundamento A evolução natural da insuficiência cardíaca é uma pior progressiva e internações hospitalares recorrentes. São necessárias estratégias para se detectar descompensações em tempo hábil. O uso do telemonitoramento da insuficiência cardíaca é inconsistente. Objetivos Este estudo tem o objetivo de avaliar o impacto desse programa de telemonitoramento (PTM) em internações hospitalares e admissões em serviços de emergência. Métodos Este é um estudo retrospectivo observacional que analisou dados de todos os pacientes que se cadastraram no PTM de janeiro a 2018 a dezembro de 2019. Foram coletados dados demográficos, clínicos e relacionados ao PTM. O número de internações hospitalares e admissões em serviços de emergência do ano anterior e posterior ao cadastro foram comparados, utilizando-se o teste de Wilcoxon. Um p-valor bilateral de <0,05 foi considerado significativo. Resultados Um total de 39 pacientes foram cadastrados, com uma média de idade de 62,1 ± 14 anos e predominância de pacientes do sexo masculino (90%). As causas mais comuns de insuficiência cardíaca foram cardiomiopatia isquêmica e dilatada. A fração de ejeção média foi de 30% e o tempo mediano da duração da doença foi de 84 meses (FIQ 33-144). Pacientes que foram cadastrados por menos de um mês foram excluídos, com um total de 34 pacientes analisados. Os pacientes foram acompanhados no PTM por um período mediano de 320 dias. O número de admissões em serviços de emergência foi reduzido em 66% (p<0,001) e o número de internações hospitalares por insuficiência cardíaca foi reduzido em 68% (p<0,001). O PTM não teve impacto no número de internações hospitalares por outras causas. Conclusões Este estudo sugere que o PTM poderia reduzir a utilização de serviços de saúde em pacientes com insuficiência cardíaca.

Abstract Background The natural history of heart failure is a progressive decline and recurrent hospital admissions. New strategies to timely detect decompensations are needed. The use of telemonitoring in heart failure is inconsistent. Objectives This study aimed to evaluate the impact of this telemonitoring program (TMP) in hospitalizations and emergency department admissions. Methods This is a retrospective observational study, that analyzed data of all the patients who enrolled in the TMP program from January 2018 to December 2019. Demographic, clinical, and TMP-related data were collected. The number of hospitalizations and emergency department admissions from the year before and after enrollment were compared, using the Wilcoxon test. A two-sided p<0.05 was considered significant. Results A total of 39 patients were enrolled, with a mean age of 62.1 ± 14 years and a male predominance (90%). The most common causes of heart failure were ischemic and dilated cardiomyopathy. The mean ejection fraction was 30% and the median time of disease duration was 84 months (IQR 33-144). Patients who were enrolled for less than one month were excluded, with a total of 34 patients analyzed. Patients were followed in the TMP for a median of 320 days. The number of emergency department admissions was reduced by 66% (p<0.001), and the number of hospitalizations for heart failure was reduced by 68% (p<0.001). The TMP had no impact on the number of hospitalizations for other causes. Conclusions This trial suggests that a TMP could reduce health service use in patients with heart failure.

https://doi.org/10.36660/abc.20201264

Cardiovascular Risk Assessment after COVID-19 Infection before Resuming Sports Activities - Practical Flowchart and Meta-Analysis
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Puga, Luís

; Dinis, Paulo

; Teixeira, Rogério

; Ribeiro, Joana Maria

; Dores, Hélder

; Gonçalves, Lino

International Journal of Cardiovascular Sciences

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feb 2022, Volume 35 N. 1 Pages 14 - 24

Abstract: En | Text: En | PDF: En

Abstract Background: The risk of sports-related sudden cardiac arrest after COVID-19 infection can be a serious problem. There is an urgent need for evidence-based criteria to ensure patient safety before resuming exercise. Objective: To estimate the pooled prevalence of acute myocardial injury caused by COVID-19 and to provide an easy-to-use cardiovascular risk assessment toolkit prior to resuming sports activities after COVID-19 infection. Methods: We searched the Medline and Cochrane databases for articles on the prevalence of acute myocardial injury associated with COVID-19 infection. The pooled prevalence of acute myocardial injury was calculated for hospitalized patients treated in different settings (non-intensive care unit [ICU], ICU, overall hospitalization, and non-survivors). Statistical significance was accepted for p values <0.05. We propose a practical flowchart to assess the cardiovascular risk of individuals who recovered from COVID-19 before resuming sports activities. Results: A total of 20 studies (6,573 patients) were included. The overall pooled prevalence of acute myocardial injury in hospitalized patients was 21.7% (95% CI 17.3-26.5%). The non-ICU setting had the lowest prevalence (9.5%, 95% CI 1.5-23.4%), followed by the ICU setting (44.9%, 95% CI 27.7-62.8%), and the cohort of non-survivors (57.7% with 95% CI 38.5-75.7%). We provide an approach to assess cardiovascular risk based on the prevalence of acute myocardial injury in each setting. Conclusions: Acute myocardial injury is frequent and associated with more severe disease and hospital admissions. Cardiac involvement could be a potential trigger for exercise-induced clinical complications after COVID-19 infection. We created a toolkit to assist with clinical decision-making prior to resuming sports activities after COVID-19 infection.

https://doi.org/10.36660/ijcs.20200288

Desigualdade socioespacial e o impacto da Covid-19 na população do Rio de Janeiro: análises e reflexões
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Ribeiro, Daniel de Albuquerque

; Braga, Aruan Francisco Diogo

; Teixeira, Lino

Cadernos Metrópole

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dec 2021, Volume 23 N. 52 Pages 949 - 970

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo A Síndrome Respiratória Aguda Grave é uma doença causada pelo novo coronavírus, cuja disseminação em escala mundial causou a pandemia da Covid-19. Este artigo tem por base a espacialização de dados governamentais relativos à capital fluminense, combinada com entrevistas e outros tipos de informações. Parte de uma perspectiva teórica que considera a ação de diferentes agentes na contribuição dos processos socioespaciais. A elaboração deste artigo teve por base o boletim Mapa Social do Corona , realizado pelo Observatório de Favelas, entre junho e agosto de 2020, que contou com a colaboração de uma equipe interdisciplinar em parceria com diferentes instituições e profissionais. Evidenciou-se como a desigualdade socioespacial contribuiu para uma taxa maior de letalidade nos bairros populares.

Abstract Severe Acute Respiratory Syndrome (SARS-COV-2) is a disease caused by the new coronavirus, whose dissemination across the world has caused the Covid-19 pandemic. This article is based on the spatialization of governmental data about the city of Rio de Janeiro, combined with interviews and other types of information. It starts from a theoretical perspective that considers the action of different agents in the contribution of socio-spatial processes. The writing of the article was grounded in the bulletin “Mapa Social do Corona” (Social Map of the Coronavirus), issued by Observatório de Favelas between June and August 2020 with the collaboration of an interdisciplinary team, in partnership with different institutions and professionals. It shows that socio-spatial inequality has contributed to a higher lethality rate in low--income neighborhoods.

https://doi.org/10.1590/2236-9996.2021-5205 1071 downloads

SORPTION OF INDAZIFLAM IN BRAZILIAN SOILS WITH DIFFERENT pH VALUES
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GONÇALVES, VALDINEI ARAÚJO

; FERREIRA, LINO ROBERTO

; TEIXEIRA, MATHEUS FERREIRA FRANÇA

; FREITAS, FRANCISCO CLÁUDIO LOPES DE

; D’ANTONINO, LEONARDO

Revista Caatinga

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sep 2021, Volume 34 N. 3 Pages 494 - 504

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Herbicidas aplicados em pré-emergência, como o indaziflam, têm eficiência agronômica quando disponíveis na solução do solo, principalmente na camada superficial (0-10 cm), região de maior concentração do banco de sementes das plantas daninhas. Contudo, as informações acerca da sorção do indaziflam em solos brasileiros ainda são escassas, pois a maioria dos estudos disponíveis na literatura foram conduzidos em solos de regiões temperadas. O objetivo desse estudo foi estimar a sorção do indaziflam, utilizando a técnica da cromatografia líquida de alta eficiência (CLAE) e do bioensaio em um Latossolo Vermelho-Amarelo e Cambissolo nos valores de pH 5,1 e 6,1. No ensaio biológico foi utilizado o Sorghum bicolor como planta indicadora. Os dados quantitativos do indaziflam foram obtidos por CLAE e os coeficientes de sorção e dessorção foram determinados em solos utilizando as isotermas de Freundlich. A elevação do valor de pH dos dois solos de 5,1 para 6,1, proporcionou diminuição da C50 e dos valores do coeficiente de sorção. A dessorção, parâmetro estimado apenas pela CLAE, apresentou comportamento inverso ao da sorção, ou seja, na condição de maior sorção foi observada a menor dessorção. A elevação do pH dos solos estudados diminui a sorção do indaziflam, influenciando as recomendações desse herbicida, tanto do ponto de vista agronômico quanto ambiental. Quando se pretende verificar a presença ou ausência do indaziflam no solo a técnica do bioensaio possui eficiência satisfatória. Na quantificação da concentração desse herbicida no solo é necessária à realização do ensaio cromatográfico. préemergência, préemergência pré emergência, emergência pré-emergência 010 0 10 (0-1 cm, cm , cm) daninhas Contudo escassas temperadas (CLAE VermelhoAmarelo Vermelho Amarelo 51 5 1 5, 61 6 6,1 indicadora Freundlich C C5 seja ambiental satisfatória cromatográfico 01 (0- 6, (0 (

ABSTRACT Pre-emergence herbicides, such as indaziflam, have agronomic efficiency when available in the soil solution, mainly in the superficial layer (0-10 cm), the region with the highest concentration of weed seed bank. However, information about the sorption of indaziflam in Brazilian soils still is scarce, since most studies available in the literature were conducted in soils of temperate regions. The objective of this study was to estimate the sorption of indaziflam using high-performance liquid chromatography (HPLC) and bioassay in a Latossolo Vermelho-Amarelo (Oxisol) and in a Cambissolo (Inceptisol), at pH values of 5.1 and 6.1. In the biossay, Sorghum bicolor was used as an indicator plant. Quantitative indaziflam data were obtained by HPLC, and the sorption and desorption coefficients were determined in the soils using Freundlich isotherms. Increasing the pH of the two soils from 5.1 to 6.1 resulted in reductions of C50 and sorption coefficient values. Desorption, a parameter estimated only by HPLC, showed an inverse behavior to that of sorption, that is, the lowest desorption was observed in the condition of highest sorption. It is concluded that the increase in pH of the studied soils reduces indaziflam sorption, influencing the recommendations of this herbicide, from both the agronomic and the environmental points of view. When the goal is to verify the presence or absence of indaziflam in the studied soils, the bioassay technique has satisfactory efficiency. Chromatographic assay is necessary when quantifying the concentration of this herbicide in the soil. Preemergence Pre emergence herbicides solution 010 0 10 (0-1 cm, cm , cm) bank However scarce regions highperformance high performance HPLC (HPLC VermelhoAmarelo Vermelho Amarelo Oxisol (Oxisol Inceptisol, Inceptisol (Inceptisol) 51 5 1 5. 61 6 biossay plant isotherms 6. C C5 Desorption view 01 (0- (Inceptisol (0 (

https://doi.org/10.1590/1983-21252021v34n301rc 66 downloads

Modelling chlorophyll-a concentrations in a continental aquatic ecosystem of the Brazilian semi-arid region based on remote sensing
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Lopes, Fernando Bezerra

; Barbosa, Cláudio Clemente Faria

; Novo, Evlyn Marcia Leão de Moraes

; Carvalho, Lino Augusto Sander de

; Andrade, Eunice Maia de

; Teixeira, Adunias dos Santos

Revista Ciência Agronômica

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2021, Volume 52 N. 2 elocation 20207210

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Os dados de sensoriamento remoto são essenciais para se avaliar processos de natureza dinâmica em sistemas aquáticos continentais, tais como a eutrofização e o aumento da concentração de sedimentos suspensos. Portanto, objetivou-se desenvolver modelos para estimar as concentrações de clorofila-a a partir de dados de sensoriamento remoto em águas continentais da região semiárida brasileira. A área de estudo corresponde ao reservatório Orós, localizado no estado do Ceará. O desenvolvimento dos modelos baseou-se em medidas realizadas em 20 pontos amostrais. Foram coletadas amostras de água no reservatório para a análise das seguintes variáveis: i) clorofila-a, condutividade elétrica, pH, turbidez; ii) medições ópticas in situ da transparência da água e da radiância espectral. As medidas de radiância foram realizadas utilizando-se espectrorradiômetro ASD FieldSpec®3 Hi-Res. Posteriormente, os dados espectrais foram transformados em reflectância e utilizados para testar o desempenho de diversos modelos de estimativa de clorofila-a disponíveis na literatura. Os resultados indicaram que para o modelo de três bandas o valor máximo do coeficiente de determinação (R2) de 0,88 foi obtido utilizando-se as bandas espectrais: λ1 = 660 nm, λ2 = 690 nm, e λ3 = 717 nm. O modelo de duas bandas espectrais apresentou melhor desempenho (R2= 0,87) para as bandas espectrais λ1 = 660 nm e λ2 = 690 nm. Os modelos apresentaram um erro médio absoluto de 5,35 e 5,00 µg L-1, respectivamente para os modelos de três e duas bandas espectrais. Os modelos desenvolvidos são confiáveis, indicando que esta variável limnológica pode ser quantificada a partir dos dados de sensoriamento remoto de campo com elevado grau de confiabilidade.

ABSTRACT Remote-sensing data are essential to evaluate dynamic processes such as eutrophication and increases in the concentration of suspended sediments in continental aquatic systems. The aim of this study, therefore, was to develop models to estimate chlorophyll-a concentrations from remote-sensing data in continental waters of the Brazilian semi-arid region. The study area corresponds to the Orós reservoir, located in the state of Ceará. The models were developed based on measurements taken at 20 sampling points. Water samples were collected from the reservoir to i) analyse the chlorophyll-a, electrical conductivity, pH and turbidity; ii) take optical measurements in situ of water transparency and spectral radiance. Radiance measurements were carried out using an ASD FieldSpec®3 Hi-Res spectroradiometer. The spectral data were later transformed into reflectance values and used to test the performance of several models found in the literature for estimating chlorophyll-a. The results showed that for the three-band model, the maximum value for the coefficient of determination (R2), of 0.88, was obtained using the λ1 = 660 nm, λ2 = 690 nm and λ3 = 717 nm spectral bands. The model employing two spectral bands presented the best performance (R2 = 0.87) in the λ1 = 660 nm and λ2 = 690 nm bands. An absolute mean error of 5.35 and 5.00 µg L-1 was found for the three- and two-band models respectively. The developed models are reliable, showing that chlorophyll-a concentrations can be quantified from remote-sensing field data with a high degree of accuracy.

https://doi.org/10.5935/1806-6690.20210028

Quality of Life in Women with Defecatory Dysfunctions: Systematic Review of Questionnaires Validated in the Portuguese Language
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Vasconcelos Neto, José Ananias

; Vasconcelos, Camila Teixeira Moreira

; Karbage, Sara Arcanjo Lino

; Farias, Hérdeny Di Cárlly de Almeida Rocha

; Machado, Stéffany Gadelha de Macêdo

; Saboia, Dayana Maia

Revista Brasileira de Ginecologia e Obstetrícia

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mar 2019, Volume 41 N. 3 Pages 191 - 198

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Objetivo Identificar os instrumentos de avaliação da qualidade de vida (QV) relacionados à saúde de mulheres com incontinência fecal (IF) ou incontinência anal (IA). Fontes dos dados Revisão sistemática nas bases de dados da BVS, PubMed e Biblioteca Cochrane. Os descritores usados foram: Questionnaire, Questionnaires, Quality of life, validation, validation Studies, anal incontinence, fecal incontinence e constipation. A pesquisa foi realizada entre 26 de dezembro de 2017 até o início de janeiro de 2018. Os limites utilizados foram sexo feminino. Seleção dos estudos Inicialmente, 5.143 artigos foram obtidos na pesquisa. Os artigos de validação para o português de questionários de avaliação do impacto da IF/IA na QV das mulheres foram considerados elegíveis. Coleta de dados A busca de artigos foi conduzida de acordo com as diretrizes do Principais Itens para Relatar Revisões Sistemáticas e Meta-análises (PRISMA, na sigla em inglês). Sínteses dos dados Dos 5.143 artigos, apenas 2 preencheram os critérios de inclusão e exclusão: Qualidade de Vida em Incontinência Fecal (FIQL, na sigla em inglês) e Escala de Wexner (WS, na sigla em inglês). O FIQL avalia a QV relacionada à FI, não abrangendo a incontinência de gases. O WS avalia a incontinência dos flatos e a gravidade da IA. O WS obteve um coeficiente de correlação interclasse (ICC, na sigla em inglês) de 0,932 e alfa de Cronbach > 0,90. O FIQL obteve reprodutibilidade intraexaminador e interexaminador variando de 0,929 a 0,957 e de 0,944 a 0,969, respectivamente. Conclusões O WS e o FIQL têm confiabilidade e validade satisfatória para uso durante consultas ginecológicas.

Abstract Objective To identify the quality of life (QoL) assessment instruments related to the health of women with fecal incontinence (FI) or anal incontinence (AI). Data Sources Systematic review conducted in the Virtual Health Library (VHL), PubMed and Cochrane Library databases. The descriptors used were: Questionnaire, Questionnaires, Quality of life, validation, validation Studies, anal incontinence, fecal incontinence and constipation. The search was performed between December 26, 2017 and the beginning of January 2018. The limits used were female gender. Selection of Studies Initially, 5,143 articles were obtained in the search. The articles of validation for Portuguese of questionnaires for the evaluation of the impact of FI/AI on the QoL of women were considered eligible. Data Collection The article search was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyzes (PRISMA) guidelines. Data Synthesis Of the 5,143 articles, only 2 fulfilled the inclusion and exclusion criteria: Fecal Incontinence Quality of Life (FIQL) and the Wexner scale (WS). The FIQL evaluates the QoL related to FI, not covering flatus incontinence. The WS assesses flatus incontinence and the severity of the AI. The WS obtained an interclass correlation coefficient (ICC) of 0.932 and a Cronbach α coefficient > 0.90. The FIQL obtained intraexaminer and interexaminer reproducibility ranging from 0.929 to 0.957 and from 0.944 to 0.969, respectively. Conclusions The WS and the FIQL have satisfactory reliability and validity for use during gynecological consultations.

https://doi.org/10.1055/s-0039-1678592 716 downloads

A Malnutrição Associada à Doença e as suas Repercussões em Portugal
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Marinho, Aníbal

; Lopes, Ana

; Sousa, Gabriela

; Antunes, Henedina

; Fonseca, Jorge

; Mendes, Lino

; Carvalho, Mamede de

; Veríssimo, Manuel Teixeira

; Carvalho, Nuno

; Alves, Paula

; Alves, Paulo

Medicina Interna

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mar 2019, Volume 26 N. 1 Pages 60 - 66

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

FA malnutrição associada à doença é frequente do ponto de vista clínico, apresentando elevada morbilidade, mortalidade e impacto na qualidade de vida, em especialidades como a medicina interna, a oncologia, a neurologia, a gastroenterologia e a pediatria, entre outras. Estudos realizados em Portugal estimam existirem cerca de 40% de doentes em risco nutricional à data da admissão hospitalar, dependendo do estadio da doença e do grau/severidade. O custo da hospitalização destes doentes, é cerca de 20% superior ao dos doentes com o mesmo grupo de diagnóstico homogéneo, mas sem risco nutricional associado. No nosso país, o acesso dos doentes malnutridos a avaliação, aconselhamento e tratamento nutricional adequados ainda é limitado, mesmo em ambiente hospitalar. Um conhecimento detalhado da malnutrição associada à doença nas referidas especialidades, permitiria uma melhor caracterização da situação em Portugal, e permitiria estabelecer uma estratégia de intervenção clínica e terapêutica, para melhorar este panorama e as suas consequências no nosso país.

Disease-related malnutrition is clinically common, with a high morbidity, mortality and quality of life impact in medical specialties like internal medicine, oncology, neurology, gastroenterology and pediatrics, among others. Studies in Portugal have estimated that about 40% of patients are at nutritional risk at hospital admission, depending on disease condition and stage/severity. The hospitalization costs for treating these patients is in average 20% higher than the respective not atrisk diagnosis-related group. The access to an adequate evaluation, counseling and nutritional treatment for malnourished patients is still limited in our country, even in the hospital setting. A detailed knowledge of disease-related malnutrition in the above mentioned medical specialties would allow to better characterize the situation in Portugal, to establish clinical and therapeutic intervention plans in order to improve the situation and consequences in our country.

https://doi.org/10.24950/rspmi/revisao/91/1/2019 1412 downloads

10.

Does Percutaneous Left Atrial Appendage Closure Affect Left Atrial Performance?
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Madeira, Marta

; Teixeira, Rogério

; Reis, Liliana

; Dinis, Paulo

; Paiva, Luís

; Botelho, Ana

; Costa, Marco

; Gonçalves, Lino

International Journal of Cardiovascular Sciences

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dec 2018, Volume 31 N. 6 Pages 569 - 577

Abstract: En | Text: En | PDF: En

Abstract Background: Percutaneous left atrial appendage (LAA) occlusion may be an alternative therapy for atrial fibrillation (AF) patients with contraindication for anti-coagulation therapy. However, the influence of LAA occlusion on left atrial (LA) performance has not been studied. Objective: Our aim was to evaluate the influence of percutaneous LAA occlusion device on LA function by transthoracic echocardiography plus speckle-tracking echocardiography (STE). Methods: We included 16 patients undergoing percutaneous LAA closure with adequate echocardiographic window for the study of LA mechanics. Transthoracic echocardiography was performed before and after the procedure. LA volumes were calculated using the biplane method, and LA mechanics were assessed using STE. The analysis focused on the LA reservoir phase strain and strain rate. Results: Seventy-five percent of patients had permanent atrial fibrillation. Embolic and bleeding risk scores used were CHA2DS2-VASc [median of 4-5] and HAS-BLED [median of 2-3]. Major bleeding (62%) was the most common indication for the procedure. Percutaneous LAA closure was performed successfully in all patients, without major complications. No differences were found in maximum LA volume (44 ± 11 vs. 46 ± 13 mL/m2; p = 0.54), minimum LA volume (32 ± 8 vs. 37 ± 14 mL/m2; p = 0.09) or LA emptying fraction (26 ± 17 vs. 21 ± 14%; p = 0.33) before and after the procedure. Similarly, no differences were noted in left atrial strain (13.7 ± 11.1 vs. 13.0 ± 8.8%; p = 0.63) or strain rate (1.06 ± 0.26 vs. 1.13 ± 0.34 s-1; p = 0.38) in the reservoir phase. Conclusions: Our data suggest that percutaneous LAA closure does not affect LA reservoir function.

https://doi.org/10.5935/2359-4802.20180075 484 downloads

11.

An exploratory evaluation of the pulpability of Brachystegia spiciformis and Pericopsis angolensis from the angolan miombo woodlands
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Sangumbe, Lino Manuel Vicente

; Pereira, Miguel

; Carrillo, Isabel

; Mendonça, Regis Teixeira

Maderas. Ciencia y tecnología

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jun 2018, Volume 20 N. 2 Pages 183 - 198

Abstract: En | Text: En | PDF: En

Abstract: Brachystegia spiciformis and Pericopsis angolensis are two hardwood species found in the Miombo woodlands. The wood features, kraft pulping and strength pulp properties of both species were evaluated in order to determine their potential as raw material for papermaking. Brachystegia spiciformis wood density was 640 kg m-3 and Pericopsis angolensis was 795 kg m-3. Pericopsis angolensis wood has higher cell wall thickness and occluded fibre lumen as remarkable anatomical properties. Runkel ratio, slenderness ratio, and the coefficients of flexibility and rigidity in Brachystegia spiciformis were 1,5; 65,7; 41,2% and 29,4% while in Pericopsis angolensis these values were 17,6; 59,9; 5,4% and 47,3%, respectively. Brachystegia spiciformis has a higher cellulose content, lower hemicellulose and lignin content, and higher S/G ratio than Pericopsis angolensis. In kraft pulping, a higher demand of active alkali was needed for both species, and pulps with high kappa number (24-27) and low pulp yield (40%) were obtained. Pericopsis angolensis pulps reached tensile, tear and burst indexes of 99,6 Nm g-1; 5,9 mN.m2 g-1 and 4,9 kPa.m2 g-1, respectively. Brachystegia spiciformis pulps reached tensile, tear and burst indexes of 100,3 Nm g-1; 10,7 mN.m2 g-1 and 6,1 kPa.m2 g-1, respectively. As a conclusion, Brachystegia spiciformis wood has better pulpability than Pericopsis angolensis wood, according to its pulps properties, despite of the similar pulp yield between both species. Both species may be suitable for unbleached wrapping papers and rigid cardboards manufacturing.

707 downloads

12.

Prevention of Sudden Cardiac Death in Hypertrophic Cardiomyopathy: What has Changed in The Guidelines?
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Reis, Liliana

; Teixeira, Rogerio

; Fernandes, Andreia

; Almeida, Inês

; Madeira, Marta

; Silva, Joana

; Botelho, Ana

; Pais, João

; Nascimento, José

; Gonçalves, Lino

Arquivos Brasileiros de Cardiologia

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jun 2018, Volume 110 N. 6 Pages 524 - 531

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Fundamento: As recomendações de miocardiopatia hipertrófica (MCH) da Sociedade Europeia de Cardiologia aconselham a estimativa do risco de morte súbita cardíaca (MSC) como parte da avaliação clínica e decisão de implantação de cardioversor desfibrilador implantável (CDI). Objetivo: Comparar a estratificação de risco de MSC de acordo com as recomendações de 2011 e 2014. Métodos: Estudo retrospectivo de 105 pacientes com diagnóstico de MCH. Avaliou-se a recomendação para implantação de CDI conforme as recomendações de 2011 e 2014. A análise estatística foi realizada usando o software SPSS versão 19.0.0.2®. Os testes realizados foram bilaterais, sendo considerado o nível de significância de 5% (p< 0,05). Resultados: Conforme as recomendações ACCF/AHA 2011, 39,0% dos pacientes tinham indicação para implantação de CDI (nível de evidência classe IIa). Conforme as recomendações de 2014, apenas 12,4% dos pacientes apresentam indicação classe IIa para implantação de CDI. Comparando os dois modelos de estratificação de risco de MSC em MCH, verificou-se uma redução significativa na proporção de pacientes com indicação para implantação de CDI (p < 0,001). Do total de 41 pacientes classificados como IIa segundo as recomendações de 2011, 68,3% deles recebeu uma classificação diferente em 2014. Conclusão: No estudo foram encontradas diferenças significativas quando comparados os métodos de estratificação de risco de MSC para implantação de CDI. O escore de risco atual parece identificar muitos pacientes de baixo risco, que não são candidatos à implantação de CDI. A utilização desse novo escore resulta numa redução significativa do número de CDI implantados.

Abstract Background: The new European Society of Cardiology guidelines for hypertrophic cardiomyopathy (HCM) define the estimation of sudden cardiac death (SCD) risk as an integral part of clinical management. An implantable cardioverter defibrillator (ICD) is recommended (class IIa) when the risk is ≥ 6%. Objectives: To compare the SCD risk stratification according to the 2011 and 2014 recommendations for ICD implantation in patients with HCM. Methods: Retrospective study including 105 patients diagnosed with HCM. The indication for ICD was assessed using the 2011 and 2014 guidelines. Statistical analysis was performed using SPSS software version 19.0.0.2®. The tests performed were bilateral, considering the significance level of 5% (p < 0.05). Results: Regarding primary prevention, according to the 2011 ACCF/AHA recommendations, 39.0% of the patients had indication for ICD implantation (level of evidence IIa). Using the 2014 guidelines, only 12.4% of the patients had an indication for ICD implantation. Comparing the two risk stratification models for patients with HCM, we detected a significant reduction in the number of indications for ICD implantation (p < 0.001). Of the 41 patients classified as IIa according to the 2011 recommendations, 68.3% received a different classification according to the 2014 guidelines. Conclusion: Significant differences were found when comparing the SCD risk stratification for ICD implantation in the two guidelines. The current SCD risk score seems to identify many low-risk patients who are not candidates for ICD implantation. The use of this new score results in a significant reduction in the number of ICD implanted.

https://doi.org/10.5935/abc.20180099 2765 downloads

13.

Eosinophilic Myocarditis: Clinical Case and Literature Review
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Dinis, Paulo

; Teixeira, Rogério

; Puga, Luís

; Lourenço, Carolina

; Cachulo, Maria Carmo

; Gonçalves, Lino

Arquivos Brasileiros de Cardiologia

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jun 2018, Volume 110 N. 6 Pages 597 - 599

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

https://doi.org/10.5935/abc.20180089 2097 downloads

14.

Additional Cardiac Remodeling Induced by Intense Military Training in Competitive Athletes
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Dinis, Paulo

; Dores, Hélder

; Teixeira, Rogério

; Moreno, Luís

; Mónico, Joselito

; Bergman, Marie

; Lekedal, Hanna

; Cachulo, Maria Carmo

; Cardoso, Joaquim

; Gonçalves, Lino

International Journal of Cardiovascular Sciences

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may 2018, Volume 31 N. 3 Pages 209 - 217

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Fundamento: A remodelagem cardíaca depende da intensidade, da duração e do método de treinamento. Objetivo: Avaliar se o treinamento realizado em uma tropa especial portuguesa incrementa a remodelagem cardíaca em uma amostra de jovens que previamente praticavam esporte de competição. Métodos: Estudo prospectivo que incluiu 76 militares candidatos a tropas especiais, 45 dos quais praticavam previamente exercício físico de nível competitivo (> 10 horas por semana). Destes militares atletas, apenas 17 concluíram com sucesso o curso. A avaliação foi realizada com 6 meses de intervalo e incluiu história clínica completa, exame físico, sinais vitais, dados antropométricos e avaliação ecocardiográfica. Considerou-se significância estatística quando p < 0,05, com intervalo de confiança de 95%. Resultados: No final do curso, verificaram-se diminuição da porcentagem de massa gorda (19,1 ± 3,3% vs. 13,1 ± 3,5%; p < 0,01), aumento da porcentagem de massa muscular (41,3 ± 2,1% vs. 44,4 ± 1,8%; p < 0,01), e diminuição da pressão arterial sistólica, diastólica e frequência cardíaca. Em relação à remodelagem cardíaca, verificaram-se aumento do diâmetro diastólico do ventrículo esquerdo (49,7 ± 3,2 mm vs. 52,8 ± 3,4 mm; p < 0,01), aumento tendencial do volume do átrio esquerdo (27,3 ± 4,5 mL/m(2) vs. 28,2 ± 4,1 mL/m(2); p = 0,07) e aumento da massa do ventrículo esquerdo (93,1 ± 7,7 g/m(2) vs. 100,2 ± 11,4 g/m(2); p < 0,01). As variáveis funcionais também sofreram alterações, com aumento do S' (15 (13-16) cm/s vs. 17 (16-18) cm/s; p < 0,01) e diminuição da fração de ejeção do ventrículo esquerdo (60 ± 6% vs. 54 ± 6%; p < 0,01). Conclusão: O treinamento físico militar intenso provocou remodelagem cardíaca adicional em atletas de nível competitivo, tanto estrutural como funcional.

Abstract Background: Cardiac remodeling depends on the intensity, duration, and training method. Objective: To evaluate if the training performed in a Portuguese military special operations troop increases cardiac remodeling in a sample of young individuals who previously practiced competitive sports. Methods: A prospective study involving 76 military candidates for military special operations, 45 of whom previously practiced at competitive level (> 10 hours per week). Of these military athletes, only 17 successfully completed the course. The evaluation was performed at 6 months intervals and included a complete clinical history, physical examination, vital signs, anthropometric data and echocardiographic evaluation. Statistical significance was considered when p < 0.05, with a 95% confidence interval. Results: At the end of the course, there was a decrease in the percentage of fat mass (19.1 ± 3.3% vs. 13.1 ± 3.5%; p < 0.01), an increase in the percentage of lean mass (41.3 ± 2.1% vs. 44.4 ± 1.8%; p < 0.01), and decreased systolic and diastolic blood pressure and heart rate. Regarding cardiac remodeling, there was an increase in left ventricular diastolic diameter (49.7 ± 3.2 mm vs. 52.8 ± 3.4 mm; p < 0.01), an increase trend in left atrial volume (27.3 ± 4.5 mL/m2 vs. 28.2 ± 4.1 mL/m2; p = 0.07) and increased left ventricular mass (93.1 ± 7.7 g/m2 vs. 100.2 ± 11.4 g/m2; p < 0.01). Functional variables also changed, with an increase in S' (15 (13-16) cm/s vs. 17 (16-18) cm/s; p < 0,01) and a decrease in left ventricular ejection fraction (60 ± 6% vs. 54 ± 6%; p < 0.01). Conclusion: Intense military physical training resulted in additional cardiac remodeling in athletes of competitive level, both structural and functional.

https://doi.org/10.5935/2359-4802.20180012 1239 downloads

15.

Sexual function of undergraduate women: a comparative study between Brazil and Italy
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Bezerra, Karine de Castro

; Feitoza, Sabrine Rodrigues

; Vasconcelos, Camila Teixeira Moreira

; Karbage, Sara Arcanjo Lino

; Saboia, Dayana Maia

; Oriá, Mônica Oliveira Batista

Revista Brasileira de Enfermagem

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2018, Volume 71 Suppl. 3 Pages 1428 - 1434

Abstract: Pt En Es | Text: Pt En Es | PDF: Pt | PDF: En | PDF: Es

RESUMO Objetivo: avaliar a função sexual de acadêmicas de enfermagem italianas e brasileiras utilizando o Female Sexual Function Index (FSFI), estimar a prevalência das disfunções sexuais e os fatores relacionados. Método: estudo transversal, o qual participaram 212 universitárias, sendo 84 brasileiras e 128 italianas. Para a avaliação da função sexual, empregou-se o questionário Female Sexual Function Index (FSFI). Resultados: As italianas apresentaram índice de disfunção sexual significativamente superior (n=78/60,9%) do que as brasileiras (n=32/38,1%) (p=0,00). Apenas os domínios “desejo” e “excitação” não apresentaram diferença entre os grupos. As mulheres mais jovens, solteiras e sem relacionamento estável apresentaram índice de disfunção sexual maior (p<0,05). Conclusão: o elevado índice de disfunção sexual em um público tão jovem sugere a necessidade da realização de mais investigações que incrementem o conhecimento sobre a influência dos fatores psicossociais e relacionais na função sexual feminina, direcionando o cuidado para a promoção da saúde sexual e reprodutiva.

ABSTRACT Objective: to evaluate the sexual function of Italian and Brazilian nursing students using the Female Sexual Function Index (FSFI), to estimate the prevalence of sexual dysfunctions and related factors. Method: this is a cross-sectional study involving 84 Brazilian and 128 Italian undergraduate. For the evaluation of sexual function, the Female Sexual Function Index (FSFI) questionnaire was used. Results: Italian women presented significantly higher sexual dysfunction index (n=78/60.9%) than the Brazilian women (n=32/38.1%) (p=0.00). Only the “desire” and “excitation” domains showed no difference between groups. Younger, single and without a steady relationship women had a higher rate of sexual dysfunction (p<0.05). Conclusion: the high rate of sexual dysfunction in a young public suggests the need for more research to increase knowledge about the influence of psychosocial and related factors on female sexual function, directing care towards the promotion of sexual and reproductive health.

RESUMEN Objetivo: evaluar la función sexual de académicas italianas y brasileñas de enfermería utilizando el Female Sexual Function Index (FSFI), estimar el predominio de las disfunciones sexuales y los factores relacionados. Método: estudio transversal, de lo cual participaron 212 universitarias, siendo 84 brasileñas y 128 italianas. Para evaluar la función sexual, se utilizó el cuestionario Female Sexual Function Index(FSFI). Resultados: Las italianas presentaron índice de disfunción sexual significativamente superior (n=78/60,9%) en comparación con el de las brasileñas (n=32/38,1%) (p=0,00). Sólo los dominios “deseo” y “excitación” no presentaron diferencia entre los grupos. Las mujeres más jóvenes, solteras y sin relación estable presentaron un índice de disfunción sexual más alto (p<0,05). Conclusión: el elevado índice de disfunción sexual en un público tan joven sugiere la necesidad de realizar más investigaciones que incrementen el conocimiento sobre la influencia de los factores psicosociales y relacionales en la función sexual femenina, dirigiendo el cuidado para la promoción de la salud sexual y reproductiva.

https://doi.org/10.1590/0034-7167-2016-0669 3670 downloads

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