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RESUMO Objetivo: Descrever o IMPACTO-MR, um estudo brasileiro de plataforma nacional em unidades de terapia intensiva focado no impacto das infecções por bactérias multirresistentes relacionadas à assistência à saúde. Métodos: Descrevemos a plataforma IMPACTO-MR, seu desenvolvimento, critérios para seleção das unidades de terapia intensiva, caracterização da coleta de dados, objetivos e projetos de pesquisa futuros a serem realizados na plataforma. Resultados: Os dados principais foram coletados por meio do Epimed Monitor System® e consistiram em dados demográficos, dados de comorbidades, estado funcional, escores clínicos, diagnóstico de internação e diagnósticos secundários, dados laboratoriais, clínicos e microbiológicos e suporte de órgãos durante a internação na unidade de terapia intensiva, entre outros. De outubro de 2019 a dezembro de 2020, 33.983 pacientes de 51 unidades de terapia intensiva foram incluídos no banco de dados principal. Conclusão: A plataforma IMPACTO-MR é um banco de dados clínico brasileiro de unidades de terapia intensiva focado na pesquisa do impacto das infecções por bactérias multirresistentes relacionadas à assistência à saúde. Essa plataforma fornece dados para o desenvolvimento e pesquisa de unidades de terapia intensiva individuais e ensaios clínicos observacionais e prospectivos multicêntricos. Objetivo IMPACTOMR, IMPACTOMR IMPACTO MR, MR saúde Métodos Resultados System demográficos comorbidades funcional secundários laboratoriais outros 201 2020 33983 33 983 33.98 5 principal Conclusão multicêntricos 20 202 3398 3 98 33.9 2 339 9 33.

ABSTRACT Objective: To describe the IMPACTO-MR, a Brazilian nationwide intensive care unit platform study focused on the impact of health care-associated infections due to multidrug-resistant bacteria. Methods: We described the IMPACTO-MR platform, its development, criteria for intensive care unit selection, characterization of core data collection, objectives, and future research projects to be held within the platform. Results: The core data were collected using the Epimed Monitor System® and consisted of demographic data, comorbidity data, functional status, clinical scores, admission diagnosis and secondary diagnoses, laboratory, clinical, and microbiological data, and organ support during intensive care unit stay, among others. From October 2019 to December 2020, 33,983 patients from 51 intensive care units were included in the core database. Conclusion: The IMPACTO-MR platform is a nationwide Brazilian intensive care unit clinical database focused on researching the impact of health care-associated infections due to multidrug-resistant bacteria. This platform provides data for individual intensive care unit development and research and multicenter observational and prospective trials. Objective IMPACTOMR, IMPACTOMR IMPACTO MR, MR careassociated associated multidrugresistant multidrug resistant bacteria Methods selection collection objectives Results System status scores diagnoses laboratory stay others 201 2020 33983 33 983 33,98 5 Conclusion trials 20 202 3398 3 98 33,9 2 339 9 33,

https://doi.org/10.5935/0103-507x.20220209-pt

Multisystem inflammatory syndrome in children (MIS-C) during SARS-CoV-2 pandemic in Brazil: a multicenter, prospective cohort study
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Lima-Setta, Fernanda

; Magalhães-Barbosa, Maria Clara de

; Rodrigues-Santos, Gustavo

; Figueiredo, Elaine Augusta das Neves

; Jacques, Melissa de Lorena

; Zeitel, Raquel de Seixas

; Sapolnik, Roberto

; Borges, Cibelle Teixeira da Siva

; Lanziotti, Vanessa Soares

; Castro, Roberta Esteves Vieira de

; Bellinat, Ana Paula Novaes

; Silva, Thiago Peres da

; Oliveira, Felipe Rezende Caino de

; Reis, Bárbara Carvalho Santos dos

; Castro, Natália Almeida de Arnaldo Silva Rodriguez

; Macedo, João Henrique Garcia Cobas

; Scarlato, Ana Carolina Cabral Pinheiro

; Riveiro, Paula Marins

; Mota, Isabele Coelho Fonseca da

; Lorenzo, Vivian Botelho

; Lucena, Natalia Martins Lima de

; Azevedo, Zina Maria Almeida de

; Cunha, Antonio José L.A.

; Prata-Barbosa, Arnaldo

Jornal de Pediatria

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jun 2021, Volume 97 N. 3 Pages 354 - 361

Abstract: En | Text: En | PDF: En

Abstract Objective To describe the clinical, laboratory, and radiological characteristics, as well as the outcomes of children with MIS-C. Method Multicenter, prospective cohort study, conducted in 17 pediatric intensive care units in five states in Brazil, from March to July 2020. Patients from 1 month to 19 years who met the MIS-C diagnostic criteria were included consecutively. Results Fifty-six patients were included, with the following conditions: Kawasaki-like disease (n = 26), incomplete Kawasaki disease (n = 16), acute cardiac dysfunction (n = 10), toxic shock syndrome (n = 3), and macrophage activation syndrome (n = 1). Median age was 6.2 years (IQR 2.4−10.3), 70% were boys, 59% were non-whites, 20% had comorbidities, 48% reported a contact with COVID-19 cases, and 55% had a recent SARS-CoV-2 infection confirmed by RT-PCR and/or serology. Gastrointestinal symptoms were present in 71%, shock symptoms in 59%, and severe respiratory symptoms in less than 20%. -Dimer was increased in 80% and cardiac dysfunction markers in more than 75%. Treatment included immunoglobulin (89%); corticosteroids, antibiotics, and enoxaparin in about 50%; and oseltamivir and antifungal therapy in less than 10%. Only 11% needed invasive mechanical ventilation, with a median duration of five days (IQR 5–6.5). The median length of PICU stay was six days (IQR 5–11), and one death occurred (1.8%). Conclusions Most characteristics of the present MIS-C patients were similar to that of other cohorts. The present results may contribute to a broader understanding of SARS-CoV-2 infection in children and its short-term consequences. Long-term multidisciplinary follow-up is needed, since it is not known whether these patients will have chronic cardiac impairment or other sequelae.

https://doi.org/10.1016/j.jped.2020.10.008 281 downloads

Effect of prednisolone on language function in children with autistic spectrum disorder: a randomized clinical trial,,
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Brito, Adriana Rocha

; Vairo, Giselle de Paula Teixeira

; Dias, Ana Paula Botelho Henriques

; Olej, Beni

; Nascimento, Osvaldo José Moreira

; Vasconcelos, Marcio Moacyr

Jornal de Pediatria

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feb 2021, Volume 97 N. 1 Pages 22 - 29

Abstract: En | Text: En | PDF: En

Abstract Objective: To describe the effect of prednisolone on language in children with autism spectrum disorder. This study is based upon two hypotheses: autism etiology may be closely related to neuroinflammation; and, an effective treatment should restore the individual's language skills. Method: This is a prospective, double-blinded, randomized, placebo-controlled clinical trial, carried out in a federal university hospital. The initial patient sample consisted of 40 subjects, which were randomized into two parallel groups. Inclusion criteria were: male gender, 3-7 years of age, and meeting the Diagnostic and Statistical Manual of Mental Disorders - 4th edition (DSM-IV) diagnostic criteria. The final sample consisted of 38 patients, of whom 20 were randomized to the placebo group and 18 to the active group. The latter received prednisolone for 24 weeks, at an initial dose of 1 mg/kg/day and a tapering dose from the ninth week onward. Language was measured on four occasions over a 12-month period by applying two Brazilian tools: the Language Development Assessment (ADL) and the Child Language Test in Phonology, Vocabulary, Fluency, and Pragmatics (ABFW). Results: The side effects were mild: two patients had hypertension, five had hyperglycemia, and two had varicella. Prednisolone increased the global ADL score in children younger than 5 years of age who had developmental regression (p = 0.0057). The ABFW's total of communicative acts also responded favorably in those participants with regression (p = 0.054). The ABFW's total of vocal acts showed the most significant results, especially in children younger than 5 years (p = 0.004, power = 0.913). Conclusions: The benefit of prednisolone for language scores was more evident in participants who were younger than five years, with a history of developmental regression, but the trial's low dose may have limited this benefit. The observed side effects do not contraindicate corticosteroid use in autism.

https://doi.org/10.1016/j.jped.2019.10.012 361 downloads

INFLAMMATORY BOWEL DISEASE CARE IN BRAZIL: HOW IT IS PERFORMED, OBSTACLES AND DEMANDS FROM THE PHYSICIANS’ PERSPECTIVE
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VILELA, Eduardo Garcia

; ROCHA, Henrique Carvalho

; MORAES, Antônio Carlos

; SANTANA, Genoile Oliveira

; PARENTE, José Miguel

; SASSAKI, Ligia Yukie

; MISZPUTEN, Sender Jenkiel

; QUARESMA, Abel Botelho

; CLARA, Ana Paula Hamer Sousa

; JESUS, Adélia Carmen Silva de

; PINTO, Arlene dos Santos

; SILVA, Bianca Loyo Pona Schiavetti da

; SILVA, Bruno César da

; FREIRE, Caio César Furtado

; SANTOS, Carlos Henrique Marques dos

; BRITO, Carlos

; TEIXEIRA, Ellen Francioni Lima

; MIRANDA, Eron Fabio

; ZABOT, Gilmara Pandolfo

; DUARTE, Jozelda Lemos

; LUDVIG, Juliano Coelho

; CAMPOS-LOBATO, Luiz Felipe de

; CASSOL, Ornella Sari

; SOUZA, Mardem Machado de

; ALMEIDA, Neogélia Pereira de

; PARRA, Rogério Serafim

; LIMA JÚNIOR, Sérgio Figueiredo de

; SAAD-HOSSNE, Rogério

Arquivos de Gastroenterologia

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dec 2020, Volume 57 N. 4 Pages 416 - 427

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO CONTEXTO: As doenças inflamatórias intestinais (DII) são afecções inflamatórias crônicas de caráter recorrente, cujas taxas de incidência e prevalência têm aumentado, inclusive no Brasil. A longo prazo, são responsáveis por danos estruturais que impactam na qualidade de vida, morbidade e mortalidade dos pacientes. OBJETIVO: Avaliar o perfil dos médicos que atendem pacientes com DII, assim como as características deste atendimento, demandas não atendidas e dificuldades. MÉTODOS: Um questionário contendo 17 variáveis foi elaborado e enviado para médicos, selecionados a partir do cadastro da Comissão das Estaduais do Grupo de Estudos da Doença Inflamatória Intestinal do Brasil (GEDIIB), totalizando 286 médicos de 101 cidades brasileiras distribuídas por 21 estados e Distrito Federal. RESULTADOS: A maioria dos médicos que respondeu o questionário foram Gastroenterologistas e Coloproctologistas. Mais de 60% tinham até 20 anos de atuação na especialidade e 53,14% trabalhavam em três locais ou mais. A dificuldade no acesso ou liberação de medicamentos ficou evidenciada neste questionário, assim como a dificuldade no encaminhamento para profissionais não médicos que atuam em DII. Mais de 75% dos médicos relataram dificuldades para realização de enteroscopia por duplo balão e cápsula endoscópica, e 67,8% para realização da calprotectina. Em relação ao número de pacientes atendidos por cada médico, foi evidenciado que não há uma concentração de pacientes sob a responsabilidade de poucos médicos. O infliximabe e o adalimumabe foram os biológicos mais utilizados e ficou evidenciada prescrição maior de derivados de 5-ASA para retocolite ulcerativa quando comparada à doença de Crohn. Os corticoides foram prescritos para uma parcela menor de pacientes em ambas doenças. Os temas “falha a terapia biológica” e “novas drogas” foram referidos como aqueles com maior prioridade para discussão em eventos científicos. Em relação às possíveis diferenças entre cada região e o restante do país, os médicos da região Norte relataram maior dificuldade no acesso a exames complementares e os médicos da região Nordeste, maior dificuldade no acesso ou liberação de medicamentos. CONCLUSÃO: Os dados obtidos por meio deste estudo mostram o perfil do atendimento médico especializado em DII e podem se constituir em ferramenta útil para para elaboração de políticas governamentais e para sociedade brasileira como um todo.

ABSTRACT BACKGROUND: Inflammatory bowel diseases (IBD) are chronic inflammatory affections of recurrent nature whose incidence and prevalence rates have increased, including in Brazil. In long term, they are responsible for structural damage that impacts quality of life, morbidity and mortality of patients. OBJECTIVE: To describe the profile of physicians who treat IBD patients as well as the characteristics of IBD care, unmet demands and difficulties. METHODS: A questionnaire containing 17 items was prepared and sent to 286 physicians from 101 Brazilian cities across 21 states and the Federal District, selected from the register of the State Commission of the “Study Group of Inflammatory Bowel Disease of Brazil” (GEDIIB). RESULTS: The majority of the physicians who answered the questionnaire were gastroenterologists and colorectal surgeons. More than 60% had up to 20 years of experience in the specialty and 53.14% worked at three or more locations. Difficulties in accessing or releasing medicines were evident in this questionnaire, as was referrals to allied healthy professionals working in IBD-related fields. More than 75% of physicians reported difficulties in performing double-balloon enteroscopy and capsule endoscopy, and 67.8% reported difficulties in measuring calprotectin. With regard to the number of patients seen by each physician, it was shown that patients do not concentrate under the responsibility of few doctors. Infliximab and adalimumab were the most commonly used biological medicines and there was a higher prescription of 5-ASA derivatives for ulcerative colitis than for Crohn’s disease. Steroids were prescribed to a smaller proportion of patients in both diseases. The topics “biological therapy failure” and “new drugs” were reported as those with higher priority for discussion in medical congresses. In relation to possible differences among the country’s regions, physicians from the North region reported greater difficulty in accessing complementary exams while those from the Northeast region indicated greater difficulty in accessing or releasing medicines. CONCLUSION: The data obtained through this study demonstrate the profile of specialized medical care in IBD and are a useful tool for the implementation of government policies and for the Brazilian society as a whole.

https://doi.org/10.1590/s0004-2803.202000000-77 1133 downloads

Conhecimento dos utentes com hipertensão arterial de uma unidade de saúde familiar sobre a sua patologia
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Ramos, Clara Lucília Botelho

; Jesus, Lisete Amélia Ribeiro de

; Souto, Ana Maria Teixeira Santos

; Santos, Ana Luísa Couto Almeida

Revista de Enfermagem Referência

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dec 2019, Volume serIV N. 23 Pages 41 - 48

Abstract: Es Pt En | Text: Es Pt En | PDF: Es | PDF: Pt | PDF: En

Marco contextual: La hipertensión arterial es el factor de riesgo de enfermedad cardiovascular (HTA) con mayor prevalencia. El conocimiento básico de la salud es la primera dimensión de la alfabetización en la salud, la cual en Portugal presenta un nivel problemático y se la considera un problema de salud pública. Objetivo: Evaluar el nivel de conocimiento de los pacientes hipertensos sobre HTA e identificar variables que puedan estar relacionados. Metodología: Estudio descriptivo-exploratorio transversal. De los 3050 pacientes hipertensos, 307 constituyeron la muestra, no probabilística y por conveniencia. Se utilizó un cuestionario para evaluar conocimiento y actitudes. Resultados: Veintisiete por ciento tiene muy buen nivel de conocimiento. Se verificó una relación estadísticamente significativa entre nivel de conocimiento y grupo de edad (p = 0,002), escolaridad (p = 0,000) y actitud hacia el tratamiento (p = 0,004); y actitud hacia el tratamiento y control de la enfermedad (p = 0,050). Conclusión: Los enfermeros deben trabajando en la formación de los pacientes, con más empeño en la población de edad avanzada.

Enquadramento: A hipertensão arterial (HTA) é o fator de risco de doença cardiovascular com maior prevalência. O conhecimento básico em saúde é a primeira dimensão da literacia em saúde (LS), que, em Portugal, apresenta um nível problemático considerando-o um problema de saúde pública. Objetivo: Avaliar o nível de conhecimentos sobre HTA dos utentes hipertensos e identificar variáveis com as quais possam estar relacionados. Metodologia: Estudo descritivo-exploratório transversal. De 3050 utentes hipertensos inscritos numa unidade de saúde familiar (USF), 307 constituíram a amostra, determinada de forma não probabilística e por conveniência. Como instrumento de colheita de dados utilizou-se um questionário que avalia conhecimentos e atitudes destes utentes face à sua patologia. Resultados: Vinte e sete por cento apresentam conhecimentos de nível muito bom. Verificou-se relação estatisticamente significativa entre nível de conhecimentos e grupo etário (p = 0,002), escolaridade (p = 0,000) e atitude face ao tratamento (p = 0,004); e atitude face ao tratamento e controlo da doença (p = 0,050). Conclusão: Os enfermeiros devem trabalhar a capacitação dos utentes, intervindo de forma incisiva na população mais idosa.

Background: High blood pressure (HBP) is the dominant risk factor for cardiovascular diseases. Basic health knowledge is the first dimension of health literacy (LS), which in Portugal presents a disturbing level, thus becoming a public health problem. Objective: To assess the level of knowledge about HBP among individuals with this condition and identify potentially related variables. Methodology: Cross-sectional descriptive study conducted in a non-probabilistic sample of 307 individuals selected by convenience from 3050 hypertensive patients registered in a family health unit (USF). For data collection, a questionnaire was used to assess the knowledge and attitudes of individuals with HBP regarding their condition. Results: Twenty-seven percent possess a very good level of knowledge. A statistically significant relationship was found between level of knowledge and age group (p = 0.002), education level (p = 0.000), and attitude toward treatment (p = 0.004); and between attitude toward treatment and control of disease (p = 0.050). Conclusion: Nurses should persist in empowering patients and intervene more closely in the oldest population.

https://doi.org/10.12707/RIV19052 1019 downloads

Fragilidade física e desempenho cognitivo em populações idosas, parte I: revisão sistemática com metanálise
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Furtado, Guilherme Eustáquio

; Letieri, Rubens

; Hogervorst, Eef

; Teixeira, Ana Botelho

; Ferreira, José Pedro

Ciência & Saúde Coletiva

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jan 2019, Volume 24 N. 1 Pages 203 - 218

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo O presente estudo teve como objetivo analisar a magnitude do efeito estatístico das diferenças de média na avaliação do desempenho cognitivo em idosos-fragilizados. A pesquisa foi realizada nas bases de dados PubMed, B-on, Ebsco, Scielo, Eric, Lilacs e Sportdiscus. Foram incluídos estudos observacionais, coorte ou transversal, selecionados a partir do título, resumo e leitura do manuscrito. Os principais descritores utilizados foram: idoso, idoso-fragilizado, cognição, avaliação geriátrica e outros termos adicionais. De 1078 manuscritos identificados, 12 foram selecionados. Quando comparados os valores de média do desempenho cognitivo dos pré-fragilizados (n = 11265) e fragilizados (n = 2460) foram encontradas diferenças significantes (p < 0,001), com valores mais baixos emergindo no grupo dos idosos-fragilizados. Os resultados demostraram que o baixo desempenho cognitivo está relacionado à condição de idoso-fragilizado, sendo um desfecho clínico provável em idosos. Nestas circunstâncias, qualquer estratégia que vise atenuar ou reverter a incidência desta condição deve ter em consideração que durante o processo de envelhecimento, a fragilidade física e a cognitiva parecem ter trajetórias temporais similares.

Abstract The purpose of present study was to analyze the magnitude of the effect-size in the assessment of the cognitive status of populations over 60 years of age. The search strategy included PubMed, B-on, Ebsco, Ebsco Health, Scielo, Eric, Lilacs and Sportdiscus data bases. Only observational, cohort and cross-sectional studies were included in the meta-analysis. The central descriptors were elderly-frail, older adults, cognition and geriatric assessment and other additional terms. After applying the additional search criteria, 12 manuscripts were selected from an initial universe of 1,078 identified. When comparing the mean cognitive profile scores of the participants of the pre-frail (n =11,265) and frail (n = 2,460) groups, significant statistical differences were found (p<0,001), with lower mean scores emerging in frail-group. The results showed that cognitive decline is strongly associated with frailty, being a probable main clinical outcome. In this sense, any strategy aimed at mitigating or reversing the incidence of frailty with ageing should take into account that physical and cognitive frailty seem to have similar temporal trajectories.

https://doi.org/10.1590/1413-81232018241.03692017 2836 downloads

Fragilidade física e desempenho cognitivo em populações idosas, parte I: revisão sistemática com metanálise
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Furtado, Guilherme Eustáquio

; Letieri, Rubens

; Hogervorst, Eef

; Teixeira, Ana Botelho

; Ferreira, José Pedro

Ciência & Saúde Coletiva

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2019, Volume 24 N. 1 Pages 203 - 218

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

https://doi.org/10.1590/1413-81232018241.03692017 4 downloads

Effect of 16-Week Blood Flow Restriction Exercise on Functional Fitness in Sarcopenic Women: A Randomized Controlled Trial
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Letieri, Rubens Vinícius

; Furtado, Guilherme Eustáquio

; Barros, Paulo Marcelo Nogueira

; Farias, Mayrhon José Abrantes de

; Antunez, Bruno Fernandes

; Gomes, Beatriz Branquinho

; Teixeira, Ana Maria Miranda Botelho

International Journal of Morphology

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2019, Volume 37 N. 1 Pages 59 - 64

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

SUMMARY: We investigated the effect of the intervention using the BFR method on functional capacity after 16 weeks in elderly women. In a controlled clinical trial, 23 women were randomly allocated into two groups, low-intensity exercise with blood flow restriction (LI + BFR, N = 11, Age: 69.40 ± 5.73) and control group (CG, N = 12, Age: 69.00 ± 6.39). The LI + BFR group had a volume of 75 repetitions at 20-30 % of 1RM and 3-4 sets per exercise (30, 15, 15 and repetitions with 30" rest between sets). The CG did not undergo any type of exercise. Functional capacity, anthropometry and sarcopenia were verified through a battery of tests before and after 16 weeks. The LI + BFR group had significant improvement in performance in Handgrip strength, Chair Stand, Arm curl, 2.44 Up-and-Go and 6 min walk, Sit-andreach and Back Scratch (p<0.05) after the intervention. The elderly women were still classified as sarcopenic, despite the improvement in the Muscle Mass Index (p<0.01). CG did not present significant changes. The BFR method can be an effective in the intervention process using physical exercise as an auxiliary strategy in the control of sarcopenia, providing a physical profile during the aging process.

RESUMEN: Investigamos en mujeres ancianas el efecto de la intervención utilizando el método de restricción del flujo sanguíneo en la capacidad funcional, después de 16 semanas. En un ensayo clínico controlado, 23 mujeres fueron asignadas aleatoriamente en dos grupos; ejercicio de baja intensidad con restricción de flujo sanguíneo (BI + RFS, N = 11, edad: 69,40 ± 5,73) y grupo control (GC, N = 12, Edad: 69,00 ± 6,39). El grupo BI + RFS tuvo un volumen de 75 repeticiones al 20-30 % de 1RM y 3-4 series por ejercicio (30, 15, 15 y repeticiones con 30 " de descanso entre series). El GC no fue sometido a ningún tipo de ejercicio. La capacidad funcional, la antropometría y la sarcopenia se verificaron mediante una batería de pruebas antes y después de 16 semanas. El grupo BI + RFS tuvo una mejora significativa en el rendimiento de la fuerza de la empuñadura, soporte de la silla, curvatura del brazo, 2,44 up-and-go y 6 min, ‘sit-and-reach’ ‘Back Scratch’ (p<0,05) después de la intervención. Las mujeres de edad avanzada seguían clasificadas como sarcopénicas, a pesar de la mejora en el índice de masa muscular (p<0,01). El GC no presentó cambios significativos. El método de restricción del flujo sanguíneo puede ser efectivo en el proceso de intervención utilizando ejercicio físico como estrategia auxiliar en el control de la sarcopenia, proporcionando un perfil físico durante el proceso de envejecimiento.

1674 downloads

Blood Pressure Responses in Isokinetic Dynamometry Test in Elderly Community Women: An Exploratory Study
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Letieri, Rubens Vinícius

; Furtado, Guilherme Eustáquio

; Rieping, Taís

; Farias, Mayrhon José Abrantes

; Teixeira, Ana Maria Miranda Botelho

Motricidade

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dec 2018, Volume 14 N. 4 Pages 52 - 56

Abstract: En | Text: En | PDF: En

The aim of the study was to verify the systolic, diastolic and mean arterial pressure response in elderly women during isokinetic test. The study included 54 females (68.8 ± 5.9 years) divided into two age groups (Group 1: 60 to 70 and group 2: above 71 years). BP was measured before and immediately after the isokinetic knee extension / flexion test in the concentric-concentric mode. After the test, significant elevations were observed in relation to the pre-test in SBP (G1: ?% = 29.7%, G2: ?% = 20.6%, p <.01, respectively) and in MAP (G1: ?% = 7.6 %, G2: ?% = 8.4%, p <.01, respectively). The use of isokinetic tests produces elevations in systolic blood pressure and mean arterial pressure in elderly women. Increases occur independently of the age group studied. However, the increases detected do not appear to be of sufficient magnitude to constitute a health hazard whereby isokinetic tests can be safely applied in this population.

https://doi.org/10.6063/motricidade.14727 324 downloads

10.

Cinética de la inmunoglobulina-A salival (IgAs) en adultos jóvenes con capacidad aeróbica promedio o excelente antes y después de una prueba de esfuerzo máximo
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Ochoa-Martínez, Paulina Yesica

; Hall-López, Javier Arturo

; Martínez-García, Marco Antonio

; Díaz-Molina, Raúl

; Miranda Botelho Teixeira, Ana María

; Moncada-Jiménez, José Antonio

Revista chilena de infectología

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feb 2017, Volume 34 N. 1 Pages 27 - 32

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

Background: Aim: To compare the concentration of secretory immunoglobulin-A (sIgA) in young adults with average or excellent aerobic capacity before and after a cardiopulmonary graded exercise test. Methods: Participants were nine apparently healthy physically active males (Mean age = 21.3 ± 2.1 yr.), randomly allocated in two groups based on their VO2max: a) average aerobic capacity (AEC, n = 5) or b) excellent aerobic capacity (EAC, n = 4). Participants performed the Bruce protocol to determine their aerobic capacity. The sIgA was measured before the test, immediately after the test and 60-, 120-, 240-, and 1440-min after the test. Results: Mixed factorial 2 x 6 ANOVA indicated no significant interactions between groups and measurements (p = 0.956), and main effect groups on sIgA (AEC = 85.4 ± 19.3 μg/mL vs. EAC = 79.2 ± 21.5 μg/mL, p = 0.836). Tukey's post hoc analysis revealed significant differences measurement obtained immediately after the test and between the initial measurement (p = 0.020), 60-min (p = 0.030), 240-min (p = 0.016), and 1440-min (p = 0.028) following the test. Conclusion: There is no change in sIgA kinetics depending on the aerobic capacity of the participants following an aerobic capacity cardiopulmonary graded exercise test.

Introducción. Objetivo: Comparar la cinética en la concentración de inmunoglobulina A salival (IgAs) en adultos jóvenes con capacidad aeróbica promedio (n: 5) o excelente (n: 4) antes y después de una prueba de esfuerzo. Método: 9 adultos jóvenes (edad 21,3 ± 2,1), divididos de acuerdo su VO2máx, realizaron una prueba de esfuerzo mediante el protocolo de Bruce. La concentración de IgAs fue determinada mediante el Salimetrics IgA Kit®, evaluando inicial, inmediatamente finalizada la prueba, +60, +120, +240, +1.440 min. Resultados: La prueba ANOVA 2x6 mixta indicó que no existieron interacciones significativas entre grupos y mediciones (p = 0,956). Tampoco se encontró una diferencia significativa en la media de IgAs en los grupos (Promedio = 85,4 ± 19.3 μg/mL vs Excelente=79,2 ± 21.5 μg/mL, p = 0,836). Independientemente de las mediciones, el análisis post hoc de Tukey indicó que las diferencias se encontraron en la medición obtenida inmediatamente después de la prueba y entre la medición inicial (p: 0,020), la medición obtenida 60 min (p: 0,030), 240 min (p: 0,016) y 1.440 min (p = 0,028) posteriores a la prueba. Conclusión: Los datos encontrados sugieren que no hay un cambio en la concentración de IgAs a través del tiempo en función de la capacidad aeróbica de los participantes.

1740 downloads

11.

Respostas agudas do lactato sanguíneo ao exercício de força com oclusão vascular periférica em jovens adultos
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Letieri, Rubens Vinícius

; Oliveira, Messias Bezerra de

; Holanda, Francisco Jeci de

; Alves Júnior, Tadeu de Almeida

; Furtado, Guilherme Eustáquio

; Teixeira, Ana Maria Miranda Botelho

Motricidade

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dec 2016, Volume 12 Suppl. 1 Pages 107 - 115

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Sugere-se que o exercício de força em baixa intensidade (20 - 40% de 1RM) combinado com restrição de fluxo sanguíneo - Blood Flow Restricted (BFR), tem produzido uma série de incrementos positivos em algumas variáveis relacionadas ao treino. Pretendemos verificar as respostas agudas do lactato sanguíneo de jovens adultos submetidos ao treino com BFR. Foram recrutados participantes do sexo masculino que não estavam engajados em qualquer tipo de treinamento de força. Participaram 37 voluntários que foram distribuídos aleatoriamente em três grupos: Grupo 1 (Exercício de baixa intensidade com oclusão vascular); Grupo 2 (Exercício de alta intensidade tradicional); Grupo 3 (Exercício de baixa intensidade sem oclusão vascular). Os indivíduos passaram por uma bateria de testes de composição corporal - Avaliação da massa corporal, estatura, Índice de Massa Corporal e percentual de gordura, análises de sangue capilar (lactato sanguíneo) e testes neuromotores (avaliação da força muscular). Foram verificadas diferenças significativas nas respostas do Lactato Sanguíneo em todos os momentos na comparação entre os grupos 1 e 3 (p<0.05) e entre os grupos 2 e 3 (p<0.05). Não foram verificadas diferenças significativas no Lactato Sanguíneo entre os grupos 1 e 2. No presente estudo observou-se que as respostas de lactato foram significativamente elevadas em diferentes momentos em relação ao estado de repouso, sobretudo nos grupos que foram submetidos à oclusão e ao treino tradicional. Fica evidente que a oclusão vascular periférica pode induzir elevações na atividade metabólica local e ser uma alternativa ao treinamento tradicional.

It is suggested that low-intensity strength training (20-40% 1RM) combined with Blood Flow Restriction (BFR) has produced a number of positive increases in some variables related to training. It was our objective to evaluate the acute responses of blood lactate in college students submitted to BFR exercise. We recruited male participants who were not engaged in any kind of strength training. The selected participants were randomized into three groups: Group 1 (low intensity exercise with vascular occlusion); Group 2 (traditional high-intensity exercise); Group 3 (low intensity exercise without vascular occlusion). The subjects underwent a battery of body composition tests - weight, height, body mass index and fat percentage, capillary blood tests (blood lactate) and neuromotor tests (evaluation of muscle strength). There were significant differences in Blood Lactate responses at all times in the comparison between groups 1 and 3 (p <0.05) and between groups 2 and 3 (p <0.05). No significant differences were found in Blood Lactate between groups 1 and 2. Conclusion: In this study it was observed that the lactate responses were significantly elevated at different times in relation to the resting state, particularly in the groups who underwent occlusion. It is evident that the peripheral vascular occlusion may induce increases in local metabolic activity and appears to be an alternative to traditional training.

3250 downloads

12.

O tempo escolar e o encontro com o outro: do ritmo padrão às simultaneidades
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Pinho, Ana Sueli Teixeira de

; Souza, Elizeu Clementino de

Educação e Pesquisa

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sep 2015, Volume 41 N. 3 Pages 663 - 678

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Este texto tem por objetivo apresentar os resultados de uma pesquisa cujo intuito foi compreender a relação entre o tempo escolar, os outros tempos sociais e as temporalidades dos sujeitos, a partir de narrativas biográficas de professoras, em duas escolas com classes multisseriadas, e sujeitos das comunidades de Botelho e Praia Grande, em Ilha de Maré (Bahia). A análise do campo empírico fez emergir o problema do tempo escolar reduzido a ritmo, ora compreendido como uma propriedade individual, ora como uma imposição de um tempo hegemônico, o do relógio. Para problematizar essa noção, foram utilizados como referencial teórico os trabalhos de Elias (1993), Faraco (2010a) e Bakhtin (2003). Com base na relação entre tempo e diferença, retomou-se a discussão com Bakhtin (2003; 2010) para, junto com Levinas (2011a, 2011b), propor outra concepção, a de tempo como simultaneidade, concebida como coexistência e interação. A pesquisa empírica adotou, como abordagem metodológica, a narrativa (auto)biográfica que se constitui na oportunidade do outro dizer de si e, ao fazê-lo, por meio da entrevista narrativa, deixar entrever traços de uma experiência ao mesmo tempo pessoal e social. A pesquisa concluiu que a compreensão do tempo escolar, de um lado, depende de um olhar atento para os outros tempos sociais que atravessam a escola, e, de outro, de uma atenção especial às interações realizadas entre os sujeitos no interior da sala de aula. Afinal, o tempo escolar é acontecimento que se dá no encontro com o outro.

This text aims to present the results of a research whose objective was to understand the relationship between school time, other social times, and the temporality of subjects, using biographical narratives of teachers in two schools with multigrade classes, and subjects of the communities Botelho and Praia Grande in Ilha da Maré (Bahia). The analysis of empirical field has unveiled the problem of school time reduced to rhythm, sometimes understood as an individual property, sometimes as an imposition of a hegemonic time, the clock time. To discuss this notion, we used as theoretical framework the works of Elias (1993), Faraco (2010a), and Bakhtin (2003). Based on the relationship between time and difference, we considered the discussion with Bakhtin (2003; 2010) and Levinas (2011a, 2011b) to propose another conception: time as simultaneity, conceived as coexistence and interaction. The methodological approach adopted in this empirical research was (auto)biographical narratives, which constitute them selves in the opportunity of the others to talk about themselves and, in doing so, through narrative interviews, to offer a glimpse of a personal and social experience. The research concluded that the understanding of school time, on the one hand, depends on a careful look at the other social times which cross school life and, on the other hand, on a special attention to interactions between subjects within the classroom. After all, school time is an event that occurs in the encounter with the other.

https://doi.org/10.1590/S1517-9702201507133096 6819 downloads

13.

Comportamento da pressão arterial em homens pré-hipertensos participantes em um programa regular de natação
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Silva, Jairo Eleotério da

; Teixeira, Ana Maria Botelho

; Dantas, Estélio Henrique Martin

; Rama, Luis Manuel Pinto Lopes

Revista Brasileira de Medicina do Esporte

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jun 2015, Volume 21 N. 3 Pages 178 - 181

Abstract: Pt En Es | Text: Pt En Es | PDF: Pt | PDF: En | PDF: Es

INTRODUÇÃO: A natação tem sido recomendada como tipo de atividade física para a prevenção, tratamento e controle da hipertensão arterial. OBJETIVO: Analisar os efeitos da prática regular de natação sobre a pressão arterial de adultos pré-hipertensos. MÉTODOS: A amostra foi composta por 36 homens pré-hipertensos divididos em dois grupos: Experimental - GE (n=24, 40,60±9,36 anos) e Controle - GC (n=12, 40,57±8,05 anos). O GE realizou um programa regular de natação, com três sessões semanais de 45 min, durante 12 semanas, enquanto o GC não alterou seus hábitos alimentares e permaneceu sem praticar atividade física no período. O procedimento estatístico utilizado para verificar as diferenças entre as médias antes e depois de 12 semanas do programa regular de natação foi o teste-t de Student. O estudo admitiu o nível de p < 0.05 para a significância estatística. RESULTADOS: O grupo GE apresentou diferenças estatisticamente significativas nas variáveis analisadas quando comparadas com o GC, tanto na pressão arterial sistólica, PAS (Δ = - 5,89 mmHg, p = 0,00), como na pressão arterial diastólica, PAD (Δ = - 5,15mmHg, p = 0,00). CONCLUSÃO: Os resultados mostram que um programa regular de natação provoca reduções significativas na pressão arterial em repouso em homens pré-hipertensos.

INTRODUCTION: Swimming as a modality of physical activity that has been recommended for preventing, controlling and treating arterial hypertension. OBJECTIVE: To verify the persistent effects of a regular swimming program on pre-hypertensive adults on arterial pressure levels. METHODS: The sample was constituted of 36 pre-hypertense individuals who were divided into two groups: experimental - GE (n=24, 40.60 ± 9.36 years old) and control - GC (n=12, 40.57 ± 8.05 years old. GE individuals took part in a regular swimming programme consisting of three forty-five training sessions weekly (ST) for 12 weeks, whereas GC individuals were instructed not to alter their nutritional habits and did not practice any physical activity during the experiment. The Student t-test was used as statistical procedure to analyze the differences between the average indexes recorded before and after the 12-weeks regular swimming program. The study admitted a level statistical significance at p < 0.05 for. RESULTS: The results led to the conclusion that experimental group presented a statistically significant difference for the analyzed variables when compared to Control group. There was an important reduction of systolic blood pressure, SBP(Δ = - 5,89 mmHg, p = 0,00), and also of diastolic blood pressure, DBP (Δ = - 5,15mmHg, p = 0,00). CONCLUSION: The results showed that a regular swimming program leads to a significant decrease in resting blood pressure values of pre-hypertensive men.

INTRODUCCIÓN: La natación ha sido recomendada como un tipo de actividad física para la prevención, tratamiento y control la de hipertensión arterial. OBJETIVO: Analizar los efectos de la práctica regular de natación sobre la presión arterial de adultos prehipertensos. MÉTODOS: La muestra se ha compuesto por 36 hombres con prehipertensión delineados en dos grupos: experimental - GE (n=24, 40,60±9,36 años) y Control - GC (n=12, 40,57±8,05 años). El GE realizó un programa regular de natación, con tres sesiones semanales, duración de 45 minutos, durante 12 semanas, mientras que el GC no cambió los hábitos alimenticios y permaneció sin realizar actividad física en el período. El procedimiento estadístico utilizado para averiguar las diferencias entre los promedios antes y después de 12 semanas del programa regular de natación fue el test t de Student. El estudio admitió el nivel de p< 0.05 para la significancia estadística. RESULTADOS: El grupo GE presentó diferencias estadísticamente significativas en las variables analizadas, cuando comparadas con el GC, tanto en la presión arterial sistólica, PAS (Δ = - 5,89 mmHg, p = 0,00) como en la presión arterial diastólica, PAD (Δ = - 5,15mmHg, p = 0,00). CONCLUSIÓN: Los resultados muestran que un programa regular de natación provoca reducciones significativas en la presión arterial en reposo en hombres prehipertensos.

https://doi.org/10.1590/1517-8692201521032115 6313 downloads

14.

Efecto del ejercicio físico de hidrogimnasia sobre la concentración sérica de inmunoglobulina A en mujeres adultas mayores
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Hall-López, Javier

; Ochoa-Martínez, Paulina

; Teixeira, Ana M. Miranda Botelho

; Moncada-Jiménez, José A

; Dantas, Estelo Martin

Revista chilena de infectología

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jun 2015, Volume 32 N. 3 Pages 272 - 277

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

Background: Decreases in function of the immune system with age contribute to the increase the risk of infectious diseases especially the upper respiratory tract. On the other hand, physical activity has been widely recommended for health. However, more studies are needed to support the benefit effect of exercise on immune system in elderly. Aim: To evaluate the effect of the hydrogymnastics on the serum level of immunoglobulin A (IgA) in elderly women. Methods: Twenty-six participants were randomly assigned to an experimental (n: 16) or a control group (n: 10). IgA concentrations were determined by nephelometry (BN2 Analyzer, Dade Behring). The hydrogymnastics training protocol was performed 5 times a week during 12 weeks. The intensity of the aerobic exercise was 50-60% of the maximum heart rate monitored by telemetry (Polar-FT7). Results: No significant differences (p: 0.797) resulted by ANOVA on serum IgA levels; the percentage of change in experimental group was Δ% = -6.7 mg/dL compared to the control group, Δ%= -7.4 mg/dL. Conclusion: After three months of hydrogymnastics the IgA level did not show significant change on elderly women; However, positive improvement in percentage of change Δ% was found.

Introducción: La disminución de la función del sistema inmune con la edad es asociada a la incidencia de enfermedades infecciosas del tracto respiratorio superior; por otro lado, el ejercicio físico ha sido ampliamente recomendado para la salud. Sin embargo se requiere aún fundamentar con mayor exactitud los efectos del ejercicio físico en el sistema inmunológico en adultos mayores. Objetivo: Evaluar el efecto de un programa de hidrogimnasia sobre la concentración sérica de Inmunoglobulina A (IgA) en adultas mayores. Métodos: 26 participantes fueron asignadas aleatoriamente a un grupo experimental (n: 16) y un grupo control (n: 10). Se determinó la concentración sérica de IgA por nefelometría (BN2 Analyser, DADE Behring). Las sesiones de hidrogimnasia se realizaron cinco veces por semana durante 12 semanas; el ejercicio fue aeróbico a una intensidad de 50-60% de la frecuencia cardíaca máxima controlada por telemetría (Polar-FT7). Resultados: Se utilizó la prueba de ANOVA, indicando no interacción significativa (p: 0,797). El porcentaje de cambio resultó de Δ% = -6,7 mg/dL del grupo experimental en comparación con el grupo control Δ% = -7,4 mg/dL. Conclusiones: Un programa de tres meses de hidrogimnasia en mujeres no mejora significativamente los niveles de IgA. Sin embargo, los datos refieren una mejora positiva el porcentaje de cambio A%.

3520 downloads

15.

Exercício e mobilização de linfócitos T senescentes: Uma meta-análise
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Minuzzi, Luciéle Guerra

; Teixeira, Ana Maria Miranda Botelho

; Ferreira, José Pedro

Motricidade

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jun 2015, Volume 11 N. 2 Pages 174 - 186

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

O objectivo deste estudo foi avaliar a hipótese que o exercício físico induz aumentos na mobilização de células T senescentes. Foi realizado um levantamento sistematizado de estudos empíricos indexados nas bases de dados PUBMED e ScienceDirect, utilizando as palavras-chave: “exercise”, “exercise-induced mobilization of T lymphocytes”, “exercise-induced mobilization of CD8”, “immune space”, “senescent T-cell mobilization”, “naive T-cell repertoire”, “senescent T-cell repertoire”. Foram encontrados 442 estudos (PUBMED = 99 estudos; ScienceDirect = 343 estudos), sendo que seis preencheram todos os critérios definidos para inclusão na meta-análise. Os estudos que cumpriram os critérios de inclusão foram avaliados quanto a qualidade metodológica com a escala de PEDro e analisados utilizando o software Comprehensive Meta-analysis. Foram calculados a diferença entre os erros padrão da média (Std diff in means), o intervalo de confiança (95% CI), e os scores Z e P (Z-value e P-value). O exercício físico aumentou a mobilização de células T senescentes para o sangue periférico, quando comparados os valores agudos obtidos logo após o término do exercício com os valores pré-exercício. É possível que esta mobilização preferencial leve a indução da apoptose destas células criando espaço para a produção de células T virgens.

The purpose of this study was to evaluate the hypothesis of increased mobilization of senescent T cells to the peripheral blood induced by exercise. The systematic survey of indexed empirical studies was conducted in PubMed and ScienceDirect databases using the keywords: “exercise”, “exercise-induced mobilization of T lymphocytes”, “exercise-induced mobilization of CD8”, “immune space”, “senescent T-cell mobilization”, “naive T-cell repertoire”, “senescent T-cell repertoire”. The main criterion was the mobilization of senescent T lymphocytes after exercise. After search, 442 studies (PUBMED = 99 studies; ScienceDirect = 343 studies) were found and six met all the criteria for inclusion in the meta- analysis. The studies that met the inclusion criteria were assessed for methodological quality with the PEDro scale. Data were analyzed using Comprehensive Meta-analysis software. The difference between the standard errors of the mean (Std diff in means), the confidence interval (95 % CI), and P and Z scores (Z-value and P-value) were calculated. In conclusion, acute exercise mobilizes a population of CD8+ T-cells exhibiting a senescent phenotype into the peripheral blood compartment. It is possible that this mobilization induces apoptosis of these cells and create a vacant space for the production of naive T cells.

https://doi.org/10.6063/motricidade.3385 1596 downloads

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