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The burden of non-communicable diseases is increasing, with risk factors emerging early in life. Physical activity reduces cardiovascular risk, but limited evidence exists for children from lower-income countries and mostly relies on self-reported methods that might be inaccurate and biased. We aimed to compare self-reported and accelerometer-measured physical activity in relation to cardiovascular risk markers in children from underserved communities in South Africa. We analysed cross-sectional data from 594 children aged 8 to 13. Physical activity was measured via accelerometry and the Physical Activity Questionnaire for Older Children (PAQ-C). Correlation analyses and linear regression models examined the relationship between accelerometer-measured and self-reported physical activity and their association with cardiovascular risk markers (body mass index, blood pressure, blood lipid profile and glycated haemoglobin). Results show a positive but weak correlation between PAQ-C scores and accelerometer-measured moderate-to-vigorous physical activity (MVPA). MVPA was inversely associated with body mass index, whilst sedentary behaviour correlated positively with lipid levels. PAQ-C scores were inversely associated with systolic blood pressure. The comparison of self-reported and accelerometer-measured physical activity in children from Gqeberha, South Africa, revealed inconsistencies in their correlation and association with cardiovascular risk markers. Accelerometry provided a more accurate cardiovascular risk estimation than PAQ-C, although associations were weak. Further, longitudinal studies should investigate the predictive power of both methodologies. These findings inform researchers and public health practitioners in the choice of method for physical activity appraisal beyond practical considerations, especially when combined with cardiovascular risk and in lower-income settings. SIGNIFICANCE: We explore two widely used methods to assess physical activity levels in children. By comparing both methods, we expose inconsistencies in their correlation and association with cardiovascular risk markers. These data can guide researchers and public health practitioners in the use of one method beyond practical considerations. Whilst this work focuses on children from marginalised areas of South Africa, the issues explored are of relevance to other lower-income settings.

https://doi.org/10.17159/sajs.2023/15494

Self-reported clinical history of misdiagnosed leprosy cases in the State of Mato Grosso, Brazil, 2016-2019 Selfreported Self reported Grosso Brazil 20162019 2016 2019 2016-201 2016201 201 2016-20 201620 20 2016-2 20162 2 2016-
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Neves, Karine Vila Real Nunes

; Machado, Lúbia Maieles Gomes

; Lisboa, Maurício Nobre

; Steinmann, Peter

; Ignotti, Eliane

Cadernos de Saúde Pública

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2023, Volume 39 N. 5 elocation e00279421

Abstract: Es Pt En | Text: Es Pt En | PDF: Es | PDF: Pt | PDF: En

El objetivo de este estudio fue analizar la historia clínica autorreportada de pacientes con diagnóstico erróneo de lepra en el estado de Mato Grosso, Brasil. Se trata de un estudio transversal de nuevos casos de lepra diagnosticados en el estado de Mato Grosso, en el periodo de 2016 a 2019, que, después de iniciar la quimioterapia multimedicamentosa, fueron dados de alta del tratamiento por errores diagnósticos. Para la recolección de datos se realizaron entrevistas telefónicas. Durante el periodo de estudio, 354 individuos con lepra fueron dados de alta del tratamiento por diagnóstico erróneo, de los cuales 162 (45,8%) fueron entrevistados. Todos los encuestados manifestaron su insatisfacción con el tratamiento, lo que llevó a una reevaluación del diagnóstico antes de ser dados de alta por “error de diagnóstico”. Entre ellos, el 35,8% tenía como diagnóstico final una enfermedad musculoesquelética o del tejido conectivo, principalmente fibromialgia y cambios en la columna, seguidos de un 13,6% con diagnóstico de enfermedades de la piel y del tejido subcutáneo. El 23,5% de los encuestados no recibieron un diagnóstico alternativo, mientras que el 7,4% fueron rediagnosticados posteriormente con lepra. Los diagnósticos erróneos de lepra se reclasificaron con mayor frecuencia como fibromialgia y problemas de columna. Aunque el diagnóstico de lepra es generalmente clínico y, en la mayoría de los casos, no requiere acceso a infraestructura técnica, algunas situaciones más complejas necesitan pruebas complementarias para su diagnóstico, así como una estrecha colaboración entre la atención primaria y los servicios de referencia. Grosso Brasil 201 2019 multimedicamentosa telefónicas 35 16 45,8% 458 45 8 (45,8% entrevistados error diagnóstico. . diagnóstico” ellos 358 35,8 conectivo columna 136 13 6 13,6 subcutáneo 235 23 5 23,5 alternativo 74 7 4 7,4 técnica referencia 20 3 1 45,8 (45,8 35, 13, 2 23, 7, 45, (45, (45 (4 (

O objetivo deste estudo foi analisar o histórico clínico autorreferido de pacientes diagnosticados erroneamente com hanseníase no Estado do Mato Grosso, Brasil. Trata-se de um estudo transversal de novos casos de hanseníase diagnosticados no Estado do Mato Grosso, de 2016 a 2019, que após o início da poliquimioterapia foram liberados do tratamento devido a erros de diagnóstico. Para a coleta de dados, foram realizadas entrevistas telefônicas. Durante o período do estudo, 354 indivíduos com hanseníase foram liberados do tratamento por erro de diagnóstico, dos quais 162 (45,8%) puderam ser entrevistados. Todos os entrevistados expressaram insatisfação com o tratamento, levando à reavaliação do diagnóstico antes de serem liberados por “erro de diagnóstico”. Dentre eles, 35,8% tinham como diagnóstico final uma doença musculoesquelética ou do tecido conjuntivo, principalmente fibromialgia e alterações na coluna vertebral, seguidos por 13,6% com diagnósticos de doenças de pele e tecido subcutâneo. Para 23,5% dos entrevistados, nenhum diagnóstico alternativo foi estabelecido, enquanto 7,4% foram posteriormente rediagnosticados com hanseníase. Diagnósticos errôneos de hanseníase foram mais frequentemente reclassificados como fibromialgia e problemas na coluna vertebral. Embora o diagnóstico da hanseníase seja geralmente clínico e não exija acesso à infraestrutura técnica na maioria dos casos, algumas situações mais complexas requerem apoio ao diagnóstico por meio de exames complementares, bem como estreita colaboração entre a atenção primária e os serviços de referência. Grosso Brasil Tratase Trata se 201 2019 dados telefônicas 35 16 45,8% 458 45 8 (45,8% . diagnóstico” eles 358 35,8 conjuntivo vertebral 136 13 6 13,6 subcutâneo 235 23 5 23,5 estabelecido 74 7 4 7,4 complementares referência 20 3 1 45,8 (45,8 35, 13, 2 23, 7, 45, (45, (45 (4 (

This study aimed to analyze the self-reported clinical history of patients misdiagnosed with leprosy in the State of Mato Grosso, Brazil. This is a cross-sectional study of new leprosy cases diagnosed in the State of Mato Grosso from 2016 to 2019, with individuals who were released from multidrug therapy due to misdiagnosis after starting treatment. Data were collected via telephone interviews. Over the study period, 354 leprosy cases were released from treatment due to misdiagnosis, of which 162 (45.8%) could be interviewed. All interviewees expressed dissatisfaction with their treatment, which prompted them to seek a reevaluation of their diagnosis before they were released due to “misdiagnosis”. Among them, 35.8% received a final diagnosis of a musculoskeletal or connective tissue disease - mainly fibromyalgia and degenerative changes in the spine - followed by 13.6% with diagnoses of skin and subcutaneous tissue diseases. For 23.5% of the respondents, no alternative diagnosis was established, whereas 7.4% were later re-diagnosed with leprosy. Fibromyalgia and spinal problems were the most common alternative diagnoses for erroneous leprosy. Although the diagnosis of leprosy is usually clinical and does not require access to technical infrastructure in most cases, some more complex situations require diagnostic support via complementary tests, as well as close collaboration between primary care and reference services. selfreported self reported Brazil crosssectional cross sectional 201 2019 interviews period 35 16 45.8% 458 45 8 (45.8% interviewed misdiagnosis. . “misdiagnosis” 358 35.8 136 13 6 13.6 diseases 235 23 5 23.5 respondents established 74 7 4 7.4 rediagnosed re tests services 20 3 1 45.8 (45.8 “misdiagnosis 35. 13. 2 23. 7. 45. (45. (45 (4 (

https://doi.org/10.1590/0102-311xen279421

Self-reported clinical history of misdiagnosed leprosy cases in the State of Mato Grosso, Brazil, 2016-2019
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Neves, Karine Vila Real Nunes

; Machado, Lúbia Maieles Gomes

; Lisboa, Maurício Nobre

; Steinmann, Peter

; Ignotti, Eliane

Cadernos de Saúde Pública

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2023, Volume 39 N. 5 elocation e00279421

Abstract: Pt Es En | Text: Pt Es En | PDF: Pt | PDF: Es | PDF: En

https://doi.org/10.1590/0102-311xen279421

Are the clinical features of leprosy and American tegumentary leishmaniasis worse in patients with both diseases?
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Carvalho, Amanda Gabriela de

; Luz, João Gabriel Guimarães

; Steinmann, Peter

; Ignotti, Eliane

Revista do Instituto de Medicina Tropical de São Paulo

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2022, Volume 64 elocation e37

Abstract: En | Text: En | PDF: En

ABSTRACT This cross-sectional population-based study compared clinical features of leprosy and American tegumentary leishmaniasis (ATL) in patients diagnosed with both diseases (n=414) and in those diagnosed with only leprosy (n=27,790) or only ATL (n=24,357) in Mato Grosso State, which is a hyperendemic area for both diseases in Midwest Brazil. All new cases of leprosy and ATL reported in the area from 2008 to 2017 were included. Patients diagnosed with both diseases were identified by a probabilistic linkage procedure applied to leprosy and ATL databases of the national reporting system. The distribution of the frequency of clinical features between groups was compared by the chi-square test, followed by a multivariate logistic regression. Patients diagnosed with both leprosy and ATL presented higher odds of having nerve damage (OR: 1.34; 95% CI: 1.09–1.66) and leprosy reactions (OR: 1.35; 95% CI: 1.04–1.76) compared to patients diagnosed only with leprosy. Mucocutaneous leishmaniasis (OR: 2.29; 95% CI: 1.74–3.00) was more frequent among patients with both diagnoses when compared to patients who only had ATL. In conclusion, patients diagnosed with both leprosy and ATL present more severe clinical features of such diseases. Our data can be useful for designing health policies aimed at timely and integrated management of leprosy and ATL in co-endemic areas.

https://doi.org/10.1590/s1678-9946202264037

Perspectives for leprosy control and elimination
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Ignotti, Eliane

; Steinmann, Peter

Cadernos de Saúde Pública

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2020, Volume 36 N. 7 elocation e00170019

Abstract: En | Text: En | PDF: En

https://doi.org/10.1590/0102-311x00170019

Perspectives for leprosy control and elimination
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Ignotti, Eliane

; Steinmann, Peter

Cadernos de Saúde Pública

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2020, Volume 36 N. 7 elocation e00170019

Abstract: En | Text: En | PDF: En

https://doi.org/10.1590/0102-311x00170019 453 downloads

Aceitabilidade da quimioprofilaxia em área endêmica para a hanseníase: projeto PEP-Hans Brasil
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Cortela, Denise da Costa Boamorte

; Ferreira, Silvana Margarida Benevidez

; Virmond, Marcos Cunha Lopes

; Mieras, Liesbeth

; Steinmann, Peter

; Ignotti, Eliane

; Cavaliero, Arielle

Cadernos de Saúde Pública

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2020, Volume 36 N. 3 elocation e00068719

Abstract: Pt En Es | Text: Pt En Es | PDF: Pt | PDF: En | PDF: Es

Resumo: O objetivo deste artigo foi analisar a aceitabilidade da quimioprofilaxia com rifampicina em dose única (PEP) entre os contatos, casos índices de hanseníase e profissionais da saúde e fatores relacionados que possam influenciar na adesão. Realizou-se um estudo qualitativo de análise de conteúdo após aplicação de entrevistas semiestruturadas segundo protocolo proposto no programa LPEP (2016), realizado em Alta Floresta, Mato Grosso, Brasil, em julho de 2016. Participaram do estudo indivíduos notificados com hanseníase, contatos e profissionais da saúde. Utilizou-se o software QRS NVivo versão 10. Foram contatados 80 indivíduos, sendo 54 (67%) contatos, 11 (14%) casos índices e 15 (19%) profissionais de saúde. Dentre os contatos, 94% (51/54) tomaram PEP. Foram identificadas 3 categorias quanto à PEP: compreensão, aceitação e expectativa da intervenção. A compreensão se mostrou relacionada ao cuidado da equipe de saúde. Aceitar ou não a medicação revelou-se relacionada ao medo, confiança e proteção, operacionalidade da estratégia, autoestima e insegurança quanto à intervenção. A expectativa da intervenção relacionou-se ao bem-estar, prevenção da doença e de sequelas, diminuição de gastos públicos e ampliação do acesso. Houve reconhecimento da relevância da estratégia PEP pela possibilidade de interrupção da cadeia de transmissão, diminuição de casos novos e melhora na qualidade de vida. A insegurança em tomar a medicação e de a doença se manifestar influenciaram negativamente à aceitação da PEP; por outro lado, as informações prévias sobre a estratégia PEP contribuíram para o fortalecimento da confiança nos profissionais de saúde e para a aceitabilidade da medicação.

Abstract: The aim was to analyze the acceptability of chemoprophylaxis with single-dose rifampicin (PEP) in contacts, index leprosy cases, and health professionals and related factors that can influence adherence. A qualitative content analysis study was performed after application of semi-structured interviews according to the protocol proposed in the LPEP program (2016) drafted at Alta Floresta, Mato Grosso State, Brazil, in July 2016. Study participants included individuals with leprosy, contacts, and health professionals. The QRS NVivo software version 10 was used. A total of 80 individuals were contacted, including 54 (67%) contacts, 11 (14%) index cases, and 15 (19%) health professionals. 94% of the contacts (51/54) took PEP. Three PEP categories were identified: understanding, acceptance, and expectation towards the intervention. Understanding proved to be related to care by the health team. Acceptance (or lack thereof) of the medication was related to fear, trust, and protection, the strategy’s operability, self-esteem, and insecurity regarding the intervention. Expectation towards the intervention was related to wellbeing, prevention of the disease, sequelae, decrease in public expenditures, and expanded access. Participants acknowledged the relevance of the PEP strategy based on the possibility of interrupting the transmission chain, reduction in new cases, and improved quality of life. Insecurity in taking the medication and the possibility of the disease manifesting itself had a negative influence on acceptance of PEP, while prior information on the PEP strategy helped strengthen trust in the health professionals and the medication’s acceptance.

Resumen: El objetivo fue analizar la aceptabilidad de la quimioprofilaxis con rifampicina en dosis única (PEP) entre los contactos, casos índices de hanseniasis y profesionales de salud, así como los factores relacionados que puedan influenciar en la adhesión al tratamiento. Se realizó un estudio cualitativo de análisis de contenido, tras la realización de entrevistas semiestructuradas, según el protocolo propuesto en el programa LPEP (2016), realizado en Alta Floresta, Mato Grosso, Brasil, en julio de 2016. Participaron en el estudio individuos diagnosticados con hanseniasis, contactos y profesionales de la salud. Se utilizó el software QRS NVivo versión 10. Se contactó con 80 individuos, siendo 54 (67%) contactos, 11 (14%) casos índices y 15 (19%) profesionales de salud. Entre los contactos 94% (51/54) tomaron PEP. Se identificaron 3 categorías respecto a la PEP: comprensión, aceptación y expectativa de intervención. La comprensión estuvo relacionada con el cuidado del equipo de salud. El aceptar o no la medicación estuvo relacionado con el miedo, confianza y protección, operatividad de la estrategia, autoestima e inseguridad de la intervención. La expectativa de la intervención estuvo relacionada con el bienestar, prevención de la enfermedad, así como secuelas, disminución de gasto público y ampliación del acceso. Existió un reconocimiento de la relevancia de la estrategia PEP por la posibilidad de interrupción de la cadena de transmisión, disminución de casos nuevos y mejora en la calidad de vida. La inseguridad en tomar la medicación y de que la enfermedad se manifestara influenciaron negativamente en la aceptación de la PEP, por otro lado, la información previa sobre la estrategia PEP contribuyó al fortalecimiento de la confianza en los profesionales de salud y a la aceptabilidad de la medicación.

https://doi.org/10.1590/0102-311x00068719 1164 downloads

Aceitabilidade da quimioprofilaxia em área endêmica para a hanseníase: projeto PEP-Hans Brasil
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Cortela, Denise da Costa Boamorte

; Ferreira, Silvana Margarida Benevidez

; Virmond, Marcos Cunha Lopes

; Mieras, Liesbeth

; Steinmann, Peter

; Ignotti, Eliane

; Cavaliero, Arielle

Cadernos de Saúde Pública

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2020, Volume 36 N. 3 elocation e00068719

Abstract: Pt En Es | Text: Pt En Es | PDF: Pt | PDF: En | PDF: Es

https://doi.org/10.1590/0102-311x00068719

Growing knowledge: an overview of Seed Plant diversity in Brazil
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Zappi, Daniela C.

; Filardi, Fabiana L. Ranzato

; Leitman, Paula

; Souza, Vinícius C.

; Walter, Bruno M.T.

; Pirani, José R.

; Morim, Marli P.

; Queiroz, Luciano P.

; Cavalcanti, Taciana B.

; Mansano, Vidal F.

; Forzza, Rafaela C.

; Abreu, Maria C.

; Acevedo-Rodríguez, Pedro

; Agra, Maria F.

; Almeida Jr., Eduardo B.

; Almeida, Gracineide S.S.

; Almeida, Rafael F.

; Alves, Flávio M.

; Alves, Marccus

; Alves-Araujo, Anderson

; Amaral, Maria C.E.

; Amorim, André M.

; Amorim, Bruno

; Andrade, Ivanilza M.

; Andreata, Regina H.P.

; Andrino, Caroline O.

; Anunciação, Elisete A.

; Aona, Lidyanne Y.S.

; Aranguren, Yani

; Aranha Filho, João L.M.

; Araújo, Andrea O.

; Araújo, Ariclenes A.M.

; Araújo, Diogo

; Arbo, María M.

; Assis, Leandro

; Assis, Marta C.

; Assunção, Vivian A.

; Athiê-Souza, Sarah M.

; Azevedo, Cecilia O.

; Baitello, João B.

; Barberena, Felipe F.V.A.

; Barbosa, Maria R.V.

; Barros, Fábio

; Barros, Lucas A.V.

; Barros, Michel J.F.

; Baumgratz, José F.A.

; Bernacci, Luis C.

; Berry, Paul E.

; Bigio, Narcísio C.

; Biral, Leonardo

; Bittrich, Volker

; Borges, Rafael A.X.

; Bortoluzzi, Roseli L.C.

; Bove, Cláudia P.

; Bovini, Massimo G.

; Braga, João M.A.

; Braz, Denise M.

; Bringel Jr., João B.A.

; Bruniera, Carla P.

; Buturi, Camila V.

; Cabral, Elza

; Cabral, Fernanda N.

; Caddah, Mayara K.

; Caires, Claudenir S.

; Calazans, Luana S.B.

; Calió, Maria F.

; Camargo, Rodrigo A.

; Campbell, Lisa

; Canto-Dorow, Thais S.

; Carauta, Jorge P.P.

; Cardiel, José M.

; Cardoso, Domingos B.O.S.

; Cardoso, Leandro J.T.

; Carneiro, Camila R.

; Carneiro, Cláudia E.

; Carneiro-Torres, Daniela S.

; Carrijo, Tatiana T.

; Caruzo, Maria B.R.

; Carvalho, Maria L.S.

; Carvalho-Silva, Micheline

; Castello, Ana C.D.

; Cavalheiro, Larissa

; Cervi, Armando C.

; Chacon, Roberta G.

; Chautems, Alain

; Chiavegatto, Berenice

; Chukr, Nádia S.

; Coelho, Alexa A.O.P.

; Coelho, Marcus A.N.

; Coelho, Rubens L.G.

; Cordeiro, Inês

; Cordula, Elizabeth

; Cornejo, Xavier

; Côrtes, Ana L.A.

; Costa, Andrea F.

; Costa, Fabiane N.

; Costa, Jorge A.S.

; Costa, Leila C.

; Costa-e-Silva, Maria B.

; Costa-Lima, James L.

; Cota, Maria R.C.

; Couto, Ricardo S.

; Daly, Douglas C.

; De Stefano, Rodrigo D.

; De Toni, Karen

; Dematteis, Massimiliano

; Dettke, Greta A.

; Di Maio, Fernando R.

; Dórea, Marcos C.

; Duarte, Marília C.

; Dutilh, Julie H.A.

; Dutra, Valquíria F.

; Echternacht, Lívia

; Eggers, Lilian

; Esteves, Gerleni

; Ezcurra, Cecilia

; Falcão Junior, Marcus J.A.

; Feres, Fabíola

; Fernandes, José M.

; Ferreira, D.M.C.

; Ferreira, Fabrício M.

; Ferreira, Gabriel E.

; Ferreira, Priscila P.A.

; Ferreira, Silvana C.

; Ferrucci, Maria S.

; Fiaschi, Pedro

; Filgueiras, Tarciso S.

; Firens, Marcela

; Flores, Andreia S.

; Forero, Enrique

; Forster, Wellington

; Fortuna-Perez, Ana P.

; Fortunato, Reneé H.

; Fraga, Cléudio N.

; França, Flávio

; Francener, Augusto

; Freitas, Joelcio

; Freitas, Maria F.

; Fritsch, Peter W.

; Furtado, Samyra G.

; Gaglioti, André L.

; Garcia, Flávia C.P.

; Germano Filho, Pedro

; Giacomin, Leandro

; Gil, André S.B.

; Giulietti, Ana M.

; A.P.Godoy, Silvana

; Goldenberg, Renato

; Gomes da Costa, Géssica A.

; Gomes, Mário

; Gomes-Klein, Vera L.

; Gonçalves, Eduardo Gomes

; Graham, Shirley

; Groppo, Milton

; Guedes, Juliana S.

; Guimarães, Leonardo R.S.

; Guimarães, Paulo J.F.

; Guimarães, Elsie F.

; Gutierrez, Raul

; Harley, Raymond

; Hassemer, Gustavo

; Hattori, Eric K.O.

; Hefler, Sonia M.

; Heiden, Gustavo

; Henderson, Andrew

; Hensold, Nancy

; Hiepko, Paul

; Holanda, Ana S.S.

; Iganci, João R.V.

; Imig, Daniela C.

; Indriunas, Alexandre

; Jacques, Eliane L.

; Jardim, Jomar G.

; Kamer, Hiltje M.

; Kameyama, Cíntia

; Kinoshita, Luiza S.

; Kirizawa, Mizué

; Klitgaard, Bente B.

; Koch, Ingrid

; Koschnitzke, Cristiana

; Krauss, Nathália P.

; Kriebel, Ricardo

; Kuntz, Juliana

; Larocca, João

; Leal, Eduardo S.

; Lewis, Gwilym P.

; Lima, Carla T.

; Lima, Haroldo C.

; Lima, Itamar B.

; Lima, Laíce F.G.

; Lima, Laura C.P.

; Lima, Leticia R.

; Lima, Luís F.P.

; Lima, Rita B.

; Lírio, Elton J.

; Liro, Renata M.

; Lleras, Eduardo

; Lobão, Adriana

; Loeuille, Benoit

; Lohmann, Lúcia G.

; Loiola, Maria I.B.

; Lombardi, Julio A.

; Longhi-Wagner, Hilda M.

; Lopes, Rosana C.

; Lorencini, Tiago S.

; Louzada, Rafael B.

; Lovo, Juliana

; Lozano, Eduardo D.

; Lucas, Eve

; Ludtke, Raquel

; Luz, Christian L.

; Maas, Paul

; Machado, Anderson F.P.

; Macias, Leila

; Maciel, Jefferson R.

; Magenta, Mara A.G.

; Mamede, Maria C.H.

; Manoel, Evelin A.

; Marchioretto, Maria S.

; Marques, Juliana S.

; Marquete, Nilda

; Marquete, Ronaldo

; Martinelli, Gustavo

; Martins da Silva, Regina C.V.

; Martins, Ângela B.

; Martins, Erika R.

; Martins, Márcio L.L.

; Martins, Milena V.

; Martins, Renata C.

; Matias, Ligia Q.

; Maya-L., Carlos A.

; Mayo, Simon

; Mazine, Fiorella

; Medeiros, Debora

; Medeiros, Erika S.

; Medeiros, Herison

; Medeiros, João D.

; Meireles, José E.

; Mello-Silva, Renato

; Melo, Aline

; Melo, André L.

; Melo, Efigênia

; Melo, José I.M.

; Menezes, Cristine G.

; Menini Neto, Luiz

; Mentz, Lilian A.

; Mezzonato, A.C.

; Michelangeli, Fabián A.

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Rodriguésia

Journal Metrics
- Sobre o periódico
- SciELO Analytics

2015, Volume 66 N. 4 Pages 1085 - 1113

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Um levantamento atualizado das plantas com sementes e análises relevantes acerca desta biodiversidade são apresentados. Este trabalho se iniciou em 2010 com a publicação do Catálogo de Plantas e Fungos e, desde então vem sendo atualizado por mais de 430 especialistas trabalhando online. O Brasil abriga atualmente 32.086 espécies nativas de Angiospermas e 23 espécies nativas de Gimnospermas e estes novos dados mostram um aumento de 3% da riqueza em relação a 2010. A Amazônia é o Domínio Fitogeográfico com o maior número de espécies de Gimnospermas, enquanto que a Floresta Atlântica possui a maior riqueza de Angiospermas. Houve um crescimento considerável no número de espécies e nas taxas de endemismo para a maioria dos Domínios (Caatinga, Cerrado, Floresta Atlântica, Pampa e Pantanal), com exceção da Amazônia que apresentou uma diminuição de 2,5% de endemicidade. Entretanto, a maior parte das plantas com sementes que ocorrem no Brasil (57,4%) é endêmica deste território. A proporção de formas de vida varia de acordo com os diferentes Domínios: árvores são mais expressivas na Amazônia e Floresta Atlântica do que nos outros biomas, ervas são dominantes no Pampa e as lianas apresentam riqueza expressiva na Amazônia, Floresta Atlântica e Pantanal. Este trabalho não só quantifica a biodiversidade brasileira, mas também indica as lacunas de conhecimento e o desafio a ser enfrentado para a conservação desta flora.

Abstract An updated inventory of Brazilian seed plants is presented and offers important insights into the country's biodiversity. This work started in 2010, with the publication of the Plants and Fungi Catalogue, and has been updated since by more than 430 specialists working online. Brazil is home to 32,086 native Angiosperms and 23 native Gymnosperms, showing an increase of 3% in its species richness in relation to 2010. The Amazon Rainforest is the richest Brazilian biome for Gymnosperms, while the Atlantic Rainforest is the richest one for Angiosperms. There was a considerable increment in the number of species and endemism rates for biomes, except for the Amazon that showed a decrease of 2.5% of recorded endemics. However, well over half of Brazillian seed plant species (57.4%) is endemic to this territory. The proportion of life-forms varies among different biomes: trees are more expressive in the Amazon and Atlantic Rainforest biomes while herbs predominate in the Pampa, and lianas are more expressive in the Amazon, Atlantic Rainforest, and Pantanal. This compilation serves not only to quantify Brazilian biodiversity, but also to highlight areas where there information is lacking and to provide a framework for the challenge faced in conserving Brazil's unique and diverse flora.

https://doi.org/10.1590/2175-7860201566411 33340 downloads

10.

Assessment of the age-specific disability weight of chronic schistosomiasis japonica
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Metrics
- SciELO Analytics

Jia, Tie-Wu

; Zhou, Xiao-Nong

; Wang, Xian-Hong

; Utzinger, Jürg

; Steinmann, Peter

; Wu, Xiao-Hua

Bulletin of the World Health Organization

Journal Metrics
- Sobre o periódico
- SciELO Analytics

jun 2007, Volume 85 N. 6 Pages 458 - 465

Abstract: En Es Fr | Text: En Es Fr | PDF: En | PDF: Es | PDF: Fr

OBJECTIVE: To estimate the age-specific disability weight of chronic schistosomiasis japonica in China. METHODS: Between October 2004 and January 2005, residents from two schistosome-endemic counties were screened for Schistosoma japonicum infection using an enzyme-linked immunosorbent assay. Disability and morbidity were assessed in seropositive individuals using the European quality of life questionnaire with an additional cognitive dimension (known as the "EQ-5D plus") and ultrasonography. The age-specific disability weight of chronic schistosomiasis was estimated based on participants’ self-rated health scores on the visual analogue scale of the questionnaire; the relationships between health status, morbidity and disability weight were explored using multilevel regression models. FINDINGS: Of 2843 seropositive individuals, 1419 (49.9%) were classified as having chronic schistosomiasis. Hepatomegaly was found in 76.3% (1082/1419); hepatic fibrosis was found in 73.3% (1040/1419); and splenomegaly was found in 18.6% (264/1419). Diarrhoea was the most common self-reported symptom (46.0%; 653/1419), followed by abdominal pain (32.6%; 463/1419), impaired capacity to work or study (30.7%; 436/1419), and blood in the stool (11.1%; 157/1419). More than half of the respondents reported impairments in at least one dimension of the EQ-5D plus questionnaire, particularly pain or discomfort (47.9%; 675/1410) and anxiety or depression (39.4%; 555/1410). The overall disability weight was 0.191, and age-specific weights ranged from 0.095 among those aged 5-14 years to 0.246 among those aged > 60 years. Multilevel regression models indicated that the disability weight was significantly associated with the participant’s sex, grade of hepatic fibrosis, the presence of hepatomegaly, abdominal pain, blood in the stool, impaired capacity to work or study, and cognition. CONCLUSION: The disability weight attributable to chronic schistosomiasis japonica is high and increases with age. Our findings call for a reappraisal of the disability weights due to chronic schistosomiasis mansoni and schistosomiasis haematobia as well as a re-estimation of the global burden of schistosomiasis.

OBJETIVO: Estimar el peso de la discapacidad por edades causada por la esquistosomiasis japonica crónica en China. MÉTODOS: Entre octubre de 2004 y enero de 2005, se sometió a cribado mediante una prueba de inmunosorción enzimática a residentes de dos circunscripciones con esquistosoma endémico a fin de detectar los casos de infección por Schistosoma japonicum. En las personas seropositivas, se procedió a evaluar la discapacidad y la morbilidad utilizando el cuestionario sobre calidad de vida europeo con una dimensión cognitiva adicional (el llamado «EQ-5D plus») y técnicas de ultrasonografía. El peso de la discapacidad por edades correspondiente a la esquistosomiasis crónica se calculó a partir de las puntuaciones de salud autoasignadas por los participantes en la escala analógica visual del cuestionario; las relaciones entre el estado de salud, la morbilidad y el peso de la discapacidad se analizaron utilizando modelos de regresión multinivel. RESULTADOS: De 2843 personas seropositivas, se diagnosticó esquistosomiasis crónica a 1419 (49,9%). Se halló hepatomegalia en un 76,3% de esos casos (1082/1419); fibrosis hepática en el 73,3% (1040/1419); y esplenomegalia en el 18,6% (264/1419). La diarrea fue el más común de los síntomas declarados espontáneamente (46,0%; 653/1419), seguido del dolor abdominal (32,6%; 463/1419), el deterioro de la capacidad para trabajar o estudiar (30,7%; 436/1419), y la presencia de sangre en las heces (11,1%; 157/1419). Más de la mitad de los encuestados notificaron trastornos al menos en una dimensión del cuestionario EQ-5D plus, en particular dolor o malestar (47,9%; 675/1410) y ansiedad o depresión (39,4%; 555/1410). El peso de discapacidad general fue del 0,191, y los pesos por edades se situaron entre 0,095 para los enfermos de 5 a 14 años y 0,246 para los de 60 años o más. Los modelos de regresión multinivel mostraron que el peso de la discapacidad estaba relacionado de forma significativa con el sexo del participante y con el grado de fibrosis hepática, la presencia de hepatomegalia, el dolor abdominal, la sangre en las heces, el deterioro de la capacidad para trabajar o estudiar y los problemas cognitivos. CONCLUSIÓN: El peso de la discapacidad atribuible a la esquistosomiasis japonica crónica es alto y aumenta con la edad. Nuestros resultados sugieren que es necesario reevaluar los pesos de la discapacidad por esquistosomiasis mansoni y esquistosomiasis haematobia crónicas, así como la carga mundial de esquistosomiasis.

OBJETIF: Estimer le poids dans l’incapacité par âge de la schistosomiase sino-japonaise chronique. MÉTHODES: Entre octobre 2004 et janvier 2005, des habitants de deux pays d’endémie de la schistosomiase ont été soumis à un dépistage de l’infection à Schistosoma japonicum à l’aide d’un test immunoenzymatique. L’incapacité et la morbidité ont été évaluées chez les individus séropositifs par l’application du questionnaire européen d’évaluation de la qualité de vie, avec détermination d’une dimension cognitive supplémentaire (connu sous l’appellation « EQ-5D plus »), suivie d’une échographie. Le poids dans l’incapacité par âge de la schistosomiase chronique a été estimé à partir des scores d’autoévaluation par les participants de leur état de santé sur l’échelle visuelle analogique du questionnaire. Les relations entre état de santé, morbidité et poids de l’incapacité ont été étudiées au moyen de modèles de régression multiniveaux. RÉSULTATS: Parmi 2843 individus séropositifs pour la schistosomiase sino-japonaise, 1419 (49,9 %) ont été classés comme atteints d’une schistosomiase chronique. On a relevé une hépatomégalie chez 76,3 % (1082/1419) de ces malades chroniques, une fibrose hépatique chez 73,3 % d’entre eux (1040/1419) et une splénomégalie chez 18,6 % (264/1419) d’entre eux. La diarrhée était le symptôme le plus couramment auto-rapporté (653cas /1419, soit 46,0 % des cas). Suivaient, par ordre de fréquence, des douleurs abdominales (463 cas/1419, soit 32,6 % des cas), une diminution de la capacité de travail ou d’étude (436 cas/1419, soit 30,7 % des cas) et la présence de sang dans les selles (157 cas/1419, soit 11,1 % des cas). Plus de la moitié des personnes interrogées ont signalé des troubles dans l’une au moins des dimensions du questionnaire EQ-5D plus, et notamment une douleur ou une gêne (675 cas/1410, soit 47,9 % des cas) et un état anxieux ou déprimé (555 cas/1410, soit 39,4 % des cas). Le poids global de la maladie dans l’incapacité était de 0,191 et la valeur du poids dans l’incapacité par âge allait de 0,095 pour la tranche d’âges 5-14 ans à 0,246 parmi les plus de 60 ans. En utilisant des modèles de régression multiniveaux, on a pu mettre en évidence des associations statistiquement significatives entre le poids de l’incapacité d’une part et le sexe du participant, le grade de son éventuelle fibrose hépatique et la présence éventuelle d’une hépatomégalie, de douleurs abdominales, de sang dans les selles ou d’une diminution de la capacité de travail ou d’étude et de la capacité cognitive.

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