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Resumo Este estudo se insere no campo da história ambiental e tem o objetivo de compreender o cenário de criação, entre 1958 e 1966, da Fundação Brasileira para a Conservação da Natureza, importante organização não governamental ambientalista brasileira, com sede no Rio de Janeiro e atuação local, nacional e internacional. Para isso, utiliza fontes documentais primárias e pesquisa bibliográfica relacionada. As conclusões demonstraram a importância da existência de organizações não governamentais mais antigas que a fundação e a influência de conservacionistas sobre sua criação e sua atuação inicial. 195 1966 Natureza brasileira local internacional isso relacionada inicial 19 196 1

Abstract This study within the field of environmental history explores the scenario amid which the Fundação Brasileira para a Conservação da Natureza (Brazilian Foundation for Nature Conservation) was founded between 1958 and 1966; this important Brazilian non-governmental organization headquartered in Rio de Janeiro worked at the local, national, and international levels. Primary documentary sources were utilized, along with research of the related literature. The conclusions demonstrate the importance of non-governmental organizations predating this foundation, and the influence of conservationists on its establishment and current work. Conservation 195 1966 nongovernmental non governmental local national levels utilized literature foundation work 19 196 1

https://doi.org/10.1590/s0104-59702024000100019en

ARE THERE ADVANTAGES IN DOUBLE TRANSIT RECONSTRUCTION AFTER TOTAL GASTRECTOMY IN PATIENTS WITH GASTRIC CANCER? A SYSTEMATIC REVIEW CANCER
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COSTA, Luigi Carlo da Silva

; MACEDO, Ary Augusto de Castro

; ARAÚJO, Juliana Mattei de

; SILVA, Ewerton Lima da

; MORAES, Luís Felipe Gomes Reis de

; SANTOS, Aline dos

; SOARES, Hugo Gomes

; TERCIOTI JUNIOR, Valdir

; COELHO NETO, João de Souza

; ANDREOLLO, Nelson Adami

; LOPES, Luiz Roberto

ABCD. Arquivos Brasileiros de Cirurgia Digestiva (São Paulo)

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2024, Volume 37 elocation e1799

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO RACIONAL: O tratamento curativo do câncer gástrico envolve a ressecção do tumor, seguida de reconstrução do trânsito, sendo o Y-de-Roux a principal técnica empregada. Para permitir o trânsito alimentar para o duodeno, ausente em Y-de-Roux, tem-se utilizado a reconstrução de duplo trânsito, cujas vantagens teóricas parecem superar a técnica anterior. OBJETIVOS: Comparar a evolução clínica de pacientes com câncer gástrico submetidos à gastrectomia total com Y-de-Roux e reconstrução de duplo trânsito. MÉTODOS: Foi realizada uma revisão sistemática nas bases de dados: Web of Science, Scopus, Embase, Scielo, Biblioteca Virtual em Saúde, PubMed e Cochrane. Os dados foram coletados até 11 de junho de 2022. Foram incluídos estudos observacionais ou ensaios clínicos avaliando pacientes que utilizaram reconstruções de duplo trânsito (DT) e Y-de-Roux (RY). Não houve restrição temporal ou de idioma. Foram excluídos artigos de revisão, relatos de casos, séries de casos e aqueles com texto incompleto. O risco de viés foi calculado utilizando a ferramenta Cochrane desenvolvida para ensaios clínicos randomizados. RESULTADOS: Foram incluídos quatro estudos de boa qualidade metodológica, abrangendo 209 participantes. No grupo RY houve maior redução na ingestão alimentar. No grupo DT, a diminuição do índice de massa corporal (IMC) foi menos pronunciada em comparação aos valores pré-operatórios. CONCLUSÕES: A reconstrução de duplo trânsito apresentou melhores resultados em relação ao índice de massa corporal e ao tempo para início de dieta leve, porém não apresentou vantagens em relação aos déficits nutricionais, qualidade de vida e complicações pós-cirúrgicas. RACIONAL tumor YdeRoux Y Roux empregada duodeno YdeRoux, Roux, temse tem se anterior OBJETIVOS MÉTODOS Science Scopus Embase Scielo Saúde 1 2022 DT (DT RY. . (RY) idioma incompleto randomizados RESULTADOS metodológica 20 participantes IMC (IMC préoperatórios. préoperatórios pré operatórios. operatórios pré-operatórios CONCLUSÕES leve nutricionais póscirúrgicas. póscirúrgicas pós cirúrgicas. cirúrgicas pós-cirúrgicas 202 (RY 2

ABSTRACT BACKGROUND: Curative treatment for gastric cancer involves tumor resection, followed by transit reconstruction, with Roux-en-Y being the main technique employed. To permit food transit to the duodenum, which is absent in Roux-en-Y, double transit reconstruction has been used, whose theoretical advantages seem to surpass the previous technique. AIMS: To compare the clinical evolution of gastric cancer patients who underwent total gastrectomy with Roux-en-Y and double tract reconstruction. METHODS: A systematic review was carried out on Web of Science, Scopus, EmbasE, SciELO, Virtual Health Library, PubMed, Cochrane, and Google Scholar databases. Data were collected until June 11, 2022. Observational studies or clinical trials evaluating patients submitted to double tract (DT) and Roux-en-Y (RY) reconstructions were included. There was no temporal or language restriction. Review articles, case reports, case series, and incomplete texts were excluded. The risk of bias was calculated using the Cochrane tool designed for randomized clinical trials. RESULTS: Four studies of good methodological quality were included, encompassing 209 participants. In the RY group, there was a greater reduction in food intake. In the DT group, the decrease in body mass index was less pronounced compared to preoperative values. CONCLUSIONS: The double tract reconstruction had better outcomes concerning body mass index and the time until starting a light diet; however, it did not present any advantages in relation to nutritional deficits, quality of life, and post-surgical complications. BACKGROUND resection RouxenY Roux en Y employed duodenum RouxenY, Y, used AIMS METHODS Science Scopus EmbasE SciELO Library PubMed databases 11 2022 (DT (RY included restriction articles reports series excluded RESULTS 20 participants group intake values CONCLUSIONS diet however deficits life postsurgical post surgical complications 1 202 2

https://doi.org/10.1590/0102-672020240006e1799

Survival Analysis in Adult Heart Transplantation: Experience from a Brazilian Single Center Transplantation
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Ferraz, Diogo Luiz de Magalhães

; Cunha, Cristiano Berardo Carneiro da

; Figueira, Fernando Augusto Marinho dos Santos

; Silva, Igor Tiago Correia

; Monteiro, Verônica Soares

; Carneiro, Rodrigo Moreno Dias

; Castro, Bruna Gomes de

; Requião, Mariana Barreto

; Oliveira, Victor de França

; Silva, Patrícia Jaqueline Xavier da

; Tchaick, Rodrigo Mezzalira

; Furtado, Ana Flávia Paiva

; Silva Filha, Maria de Fátima Oliveira da

; Souza, Renato Correia Fernandes de

; Mello, Maria Julia Gonçalves de

; Gallindo, Rodrigo Melo

Brazilian Journal of Cardiovascular Surgery

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2024, Volume 39 N. 5 elocation e20230394

Abstract: En | Text: En | PDF: En

ABSTRACT Introduction: Heart transplantation is the gold standard for advanced heart failure treatment. This study examines the survival rates and risk factors for early mortality in adult heart transplant recipients at a Brazilian center. Methods: This retrospective cohort study involved 255 adult heart transplant patients from a single center in Brazil. Data were collected from medical records and databases including three defined periods (2012-2015, 2016-2019, and 2020-2022). Statistical analysis employed Kaplan-Meier survival curves, Cox proportional hazards analysis for 30-day mortality risk factors, and Log-rank tests. Results: The recipients were mostly male (74.9%), and the mean age was 46.6 years. Main causes of heart failure were idiopathic dilated cardiomyopathy (33.9%), Chagas cardiomyopathy (18%), and ischemic cardiomyopathy (14.3%). The study revealed an overall survival of 68.1% at one year, 58% at five years, and 40.8% at 10 years after heart transplantation. Survivalimproved significantly over time, combining the most recent periods (2016 to 2022) it was 73.2% in the first year and 63% in five years. The main risk factors for 30-day mortality were longer time on cardiopulmonary bypass, the initial period of transplants (2012 to 2015), older age of the donor, and nutritional status of the donor (overweight or obese). The main causes of death within 30 days post-transplant were infection and primary graft dysfunction. Conclusion: The survival analysis by period demonstrated that the increased surgical volume, coupled with the team’s experience and modifications to the immunosuppression protocol, contributed to the improved early and mid-term outcomes. Introduction treatment Methods 25 Brazil 20122015, 20122015 2012 2015, 2015 (2012-2015 20162019, 20162019 2016 2019, 2019 2016-2019 20202022. 20202022 2020 2022 . 2020-2022) KaplanMeier Kaplan Meier curves 30day day Logrank Log rank tests Results 74.9%, 749 74.9% , 74 9 (74.9%) 466 46 6 46. 33.9%, 339 33.9% 33 (33.9%) 18%, 18 18% (18%) 14.3%. 143 14.3% 14 3 (14.3%) 681 68 1 68.1 58 408 40 8 40.8 (201 732 73 2 73.2 63 bypass 2015) overweight obese. obese obese) posttransplant post dysfunction Conclusion volume teams team s protocol midterm mid term outcomes 2012201 201 (2012-201 2016201 2016-201 2020202 202 2020-2022 74.9 7 (74.9% 4 33.9 (33.9% (18% 14.3 (14.3% 68. 5 40. (20 73. 201220 20 (2012-20 201620 2016-20 202020 2020-202 74. (74.9 33. (33.9 (18 14. (14.3 (2 20122 (2012-2 20162 2016-2 20202 2020-20 (74. (33. (1 (14. ( (2012- 2016- 2020-2 (74 (33 (14 2020- (7 (3

https://doi.org/10.21470/1678-9741-2023-0394

Diretriz Brasileira de Ergometria em População Adulta – 2024 202 20 2
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Carvalho, Tales de

; Freitas, Odilon Gariglio Alvarenga de

; Chalela, William Azem

; Hossri, Carlos Alberto Cordeiro

; Milani, Mauricio

; Buglia, Susimeire

; Precoma, Dalton Bertolim

; Falcão, Andréa Maria Gomes Marinho

; Mastrocola, Luiz Eduardo

; Castro, Iran

; Albuquerque, Pedro Ferreira de

; Coutinho, Ricardo Quental

; Brito, Fabio Sandoli de

; Alves, Josmar de Castro

; Serra, Salvador Manoel

; Santos, Mauro Augusto dos

; Colombo, Clea Simone Sabino de Souza

; Stein, Ricardo

; Herdy, Artur Haddad

; Silveira, Anderson Donelli da

; Castro, Claudia Lucia Barros de

; Silva, Miguel Morita Fernandes da

; Meneghello, Romeu Sergio

; Ritt, Luiz Eduardo Fonteles

; Malafaia, Felipe Lopes

; Marinucci, Leonardo Filipe Benedeti

; Pena, José Luiz Barros

; Almeida, Antônio Eduardo Monteiro de

; Vieira, Marcelo Luiz Campos

; Stier Júnior, Arnaldo Laffitte

Arquivos Brasileiros de Cardiologia

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2024, Volume 121 N. 3 elocation e20240110

Abstract: Pt | Text: Pt | PDF: Pt

https://doi.org/10.36660/abc.20240110

[SciELO Preprints] - Brazilian Guidelines for In-office and Out-of-office Blood Pressure Measurement – 2023
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Feitosa, Audes Diógenes de Magalhães Barroso, Weimar Kunz Sebba Mion Júnior, Décio Nobre, Fernando Mota-Gomes, Marco Antonio Jardim, Paulo Cesar Brandão Veiga Amodeo, Celso Camargo, Adriana Alessi, Alexandre Sousa, Ana Luiza Lima Brandão, Andréa Araujo Pio-Abreu, Andrea Sposito, Andrei Carvalho Pierin, Angela Maria Geraldo Paiva, Annelise Machado Gomes de Spinelli, Antonio Carlos de Souza Machado, Carlos Alberto Poli-de-Figueiredo, Carlos Eduardo Rodrigues, Cibele Isaac Saad Forjaz, Cláudia Lúcia de Moraes Sampaio, Diogo Pereira Santos Barbosa, Eduardo Costa Duarte Freitas, Elizabete Viana de Cestário , Elizabeth do Espírito Santo Muxfeldt, Elizabeth Silaid Lima Júnior, Emilton Campana, Erika Maria Gonçalves Feitosa, Fabiana Gomes Aragão Magalhães Consolim-Colombo, Fernanda Marciano Almeida, Fernando Antônio de Silva, Giovanio Vieira da Moreno Júnior, Heitor Finimundi, Helius Carlos Guimarães, Isabel Cristina Britto Gemelli, João Roberto Barreto Filho, José Augusto Soares Vilela-Martin, José Fernando Ribeiro, José Marcio Yugar-Toledo, Juan Carlos Magalhães, Lucélia Batista Neves Cunha Drager, Luciano Ferreira Bortolotto, Luiz Aparecido Alves, Marco Antonio de Melo Malachias, Marcus Vinícius Bolívar Neves, Mario Fritsch Toros Santos, Mayara Cedrim Dinamarco, Nelson Moreira Filho, Osni Passarelli Júnior, Oswaldo Valverde de Oliveira Vitorino, Priscila Valverde de Oliveira Miranda, Roberto Dischinger Bezerra, Rodrigo Pedrosa, Rodrigo Pinto Paula, Rogério Baumgratz de Okawa, Rogério Toshiro Passos Póvoa, Rui Manuel dos Santos Fuchs, Sandra C. Inuzuka, Sayuri Ferreira-Filho, Sebastião R. Paffer Fillho, Silvio Hock de Jardim, Thiago de Souza Veiga Guimarães Neto, Vanildo da Silva Koch, Vera Hermina Gusmão, Waléria Dantas Pereira Oigman, Wille Nadruz, Wilson

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Publication date: 2023-09-23

Abstract: En Es Pt

Hypertension is one of the primary modifiable risk factors for morbidity and mortality worldwide, being a major risk factor for coronary artery disease, stroke, and kidney failure. Furthermore, it is highly prevalent, affecting more than one-third of the global population. Blood pressure measurement is a MANDATORY procedure in any medical care setting and is carried out by various healthcare professionals. However, it is still commonly performed without the necessary technical care. Since the diagnosis relies on blood pressure measurement, it is clear how important it is to handle the techniques, methods, and equipment used in its execution with care. It should be emphasized that once the diagnosis is made, all short-term, medium-term, and long-term investigations and treatments are based on the results of blood pressure measurement. Therefore, improper techniques and/or equipment can lead to incorrect diagnoses, either underestimating or overestimating values, resulting in inappropriate actions and significant health and economic losses for individuals and nations. Once the correct diagnosis is made, as knowledge of the importance of proper treatment advances, with the adoption of more detailed normal values and careful treatment objectives towards achieving stricter blood pressure goals, the importance of precision in blood pressure measurement is also reinforced. Blood pressure measurement (described below) is usually performed using the traditional method, the so-called casual or office measurement. Over time, alternatives have been added to it, through the use of semi-automatic or automatic devices by the patients themselves, in waiting rooms or outside the office, in their own homes, or in public spaces. A step further was taken with the use of semi-automatic devices equipped with memory that allow sequential measurements outside the office (ABPM; or HBPM) and other automatic devices that allow programmed measurements over longer periods (HBPM). Some aspects of blood pressure measurement can interfere with obtaining reliable results and, consequently, cause harm in decision-making. These include the importance of using average values, the variation in blood pressure during the day, and short-term variability. These aspects have encouraged the performance of a greater number of measurements in various situations, and different guidelines have advocated the use of equipment that promotes these actions. Devices that perform HBPM or ABPM, which, in addition to allowing greater precision, when used together, detect white coat hypertension (WCH), masked hypertension (MH), sleep blood pressure alterations, and resistant hypertension (RHT) (defined in Chapter 2 of this guideline), are gaining more and more importance. Taking these details into account, we must emphasize that information related to diagnosis, classification, and goal setting is still based on office blood pressure measurement, and for this reason, all attention must be given to the proper execution of this procedure.

La hipertensión arterial (HTA) es uno de los principales factores de riesgo modificables para la morbilidad y mortalidad en todo el mundo, siendo uno de los mayores factores de riesgo para la enfermedad de las arterias coronarias, el accidente cerebrovascular (ACV) y la insuficiencia renal. Además, es altamente prevalente y afecta a más de un tercio de la población mundial. La medición de la presión arterial (PA) es un procedimiento OBLIGATORIO en cualquier atención médica o realizado por diferentes profesionales de la salud. Sin embargo, todavía se realiza comúnmente sin los cuidados técnicos necesarios. Dado que el diagnóstico se basa en la medición de la PA, es claro el cuidado que debe haber con las técnicas, los métodos y los equipos utilizados en su realización. Debemos enfatizar que una vez realizado el diagnóstico, todas las investigaciones y tratamientos a corto, mediano y largo plazo se basan en los resultados de la medición de la PA. Por lo tanto, las técnicas y/o equipos inadecuados pueden llevar a diagnósticos incorrectos, subestimando o sobreestimando valores y resultando en conductas inadecuadas y pérdidas significativas para la salud y la economía de las personas y las naciones. Una vez realizado el diagnóstico correcto, a medida que avanza el conocimiento sobre la importancia del tratamiento adecuado, con la adopción de valores de normalidad más detallados y objetivos de tratamiento más cuidadosos hacia metas de PA más estrictas, también se refuerza la importancia de la precisión en la medición de la PA. La medición de la PA (descrita a continuación) generalmente se realiza mediante el método tradicional, la llamada medición casual o de consultorio. Con el tiempo, se han agregado alternativas a través del uso de dispositivos semiautomáticos o automáticos por parte del propio paciente, en salas de espera o fuera del consultorio, en su propia residencia o en espacios públicos. Se dio un paso más con el uso de dispositivos semiautomáticos equipados con memoria que permiten mediciones secuenciales fuera del consultorio (AMPA; o MRPA) y otros automáticos que permiten mediciones programadas durante períodos más largos (MAPA). Algunos aspectos en la medición de la PA pueden interferir en la obtención de resultados confiables y, en consecuencia, causar daños en las decisiones a tomar. Estos incluyen la importancia de usar valores promedio, la variación de la PA durante el día y la variabilidad a corto plazo. Estos aspectos han alentado la realización de un mayor número de mediciones en diversas situaciones, y diferentes pautas han abogado por el uso de equipos que promuevan estas acciones. Los dispositivos que realizan MRPA o MAPA, que además de permitir una mayor precisión, cuando se usan juntos, detectan la hipertensión de bata blanca (HBB), la hipertensión enmascarada (HM), las alteraciones de la PA durante el sueño y la hipertensión resistente (HR) (definida en el Capítulo 2 de esta guía), están ganando cada vez más importancia. Teniendo en cuenta estos detalles, debemos enfatizar que la información relacionada con el diagnóstico, la clasificación y el establecimiento de objetivos todavía se basa en la medición de la presión arterial en el consultorio, y por esta razón, se debe prestar toda la atención a la ejecución adecuada de este procedimiento.

A hipertensão arterial (HA) é um dos principais fatores de risco modificáveis para morbidade e mortalidade em todo o mundo, sendo um dos maiores fatores de risco para doença arterial coronária, acidente vascular cerebral (AVC) e insuficiência renal. Além disso, é altamente prevalente e atinge mais de um terço da população mundial. A medida da PA é procedimento OBRIGATÓRIO em qualquer atendimento médico ou realizado por diferentes profissionais de saúde. Contudo, ainda é comumente realizada sem os cuidados técnicos necessários. Como o diagnóstico se baseia na medida da PA, fica claro o cuidado que deve haver com as técnicas, os métodos e os equipamentos utilizados na sua realização. Deve-se reforçar que, feito o diagnóstico, toda a investigação e os tratamentos de curto, médio e longo prazos são feitos com base nos resultados da medida da PA. Assim, técnicas e/ou equipamentos inadequados podem levar a diagnósticos incorretos, tanto subestimando quanto superestimando valores e levando a condutas inadequadas e grandes prejuízos à saúde e à economia das pessoas e das nações. Uma vez feito o diagnóstico correto, na medida em que avança o conhecimento da importância do tratamento adequado, com a adoção de valores de normalidade mais detalhados e com objetivos de tratamento mais cuidadosos no sentido do alcance de metas de PA mais rigorosas, fica também reforçada a importância da precisão na medida da PA. A medida da PA (descrita a seguir) é habitualmente feita pelo método tradicional, a assim chamada medida casual ou de consultório. Ao longo do tempo, foram agregadas alternativas a ela, mediante o uso de equipamentos semiautomáticos ou automáticos pelo próprio paciente, nas salas de espera ou fora do consultório, em sua própria residência ou em espaços públicos. Um passo adiante foi dado com o uso de equipamentos semiautomáticos providos de memória que permitem medidas sequenciais fora do consultório (AMPA; ou MRPA) e outros automáticos que permitem medidas programadas por períodos mais prolongados (MAPA). Alguns aspectos na medida da PA podem interferir na obtenção de resultados fidedignos e, consequentemente, causar prejuízo nas condutas a serem tomadas. Entre eles, estão: a importância de serem utilizados valores médios, a variação da PA durante o dia e a variabilidade a curto prazo. Esses aspectos têm estimulado a realização de maior número de medidas em diversas situações, e as diferentes diretrizes têm preconizado o uso de equipamentos que favoreçam essas ações. Ganham cada vez mais espaço os equipamentos que realizam MRPA ou MAPA, que, além de permitirem maior precisão, se empregados em conjunto, detectam a HA do avental branco (HAB), HA mascarada (HM), alterações da PA no sono e HA resistente (HAR) (definidos no Capítulo 2 desta diretriz). Resguardados esses detalhes, devemos ressaltar que as informações relacionadas a diagnóstico, classificação e estabelecimento de metas ainda são baseadas na medida da PA de consultório e, por esse motivo, toda a atenção deve ser dada à realização desse procedimento.

https://doi.org/10.1590/SciELOPreprints.7057

Can composite packaging and selective enamel etching affect the clinical behavior of bulk-fill composite resin in posterior restorations? 24-month results of a randomized clinical trial bulkfill bulk fill restorations 24month month 24 2
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BARCELEIRO, Marcos de Oliveira

; TARDEM, Chane

; ALBUQUERQUE, Elisa Gomes

; LOPES, Leticia de Souza

; MARINS, Stella Soares

; POUBEL, Luiz Augusto

; BARCELOS, Roberta

; ÑAUPARI-VILLASANTE, Romina

; LOGUERCIO, Alessandro Dourado

; CALAZANS, Fernanda Signorelli

Journal of Applied Oral Science

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2023, Volume 31 elocation e20220323

Abstract: En | Text: En | PDF: En

Abstract Objectives This is a double-blind, split-mouth, randomized clinical study that aims to evaluate the influence of bulk-fill composite packaging presented in syringes (BSy) and capsules (BCa), and the effect of selective enamel etching (SEE) on the clinical performance of class I and II bulk-fill resin composite restorations after 24 months. Methodology A total of 295 class I or class II restorations were performed on 70 patients. One universal adhesive was applied in all restorations. SEE was used in 148 restorations and self-etching mode (SET) in 147 restorations. After the adhesive application, cavities were restored with Filtek Bulk-fill Posterior Restorative in syringes (BSy), Filtek One Bulk-fill in capsules (BCa), or Filtek Supreme Ultra in syringes with the incremental technique (In). All restorations were evaluated using the FDI criteria after one week and after six, 12, and 24 months. Kaplan-Meier survival analysis and Pearson’s Chi-square test were used (α=0.05) for statistical analysis. Results After 24 months, 62 patients were evaluated and four restorations were lost due to fracture (one for SEEBSy, two for SEEIn, and one for SETIn). No significant differences in the fracture and retention rate were found between groups (p>0.05). SEE showed significantly fewer marginal adaptation defects than SET (p<0.05). BCa and BSy groups showed fewer marginal discrepancies compared to In (p<0.05). Restorations performed with BCa showed less color mismatch than BSy or In (p<0.05). Conclusion Although all restorations exhibited satisfactory clinical performance after 24 months of clinical service, the clinical behavior of class I and II restorations’ improved when performed with a bulk-fill composite in capsules, mainly when associated with a universal adhesive applied with SEE. doubleblind, doubleblind double blind, blind double-blind splitmouth, splitmouth split mouth, mouth split-mouth bulkfill bulk fill (BSy BCa, , (BCa) (SEE 2 29 7 14 selfetching self (SET application Bulkfill Bulk BSy, In. . (In) six 12 KaplanMeier Kaplan Meier Pearsons Pearson s Chisquare Chi square α=0.05 α005 α 0 05 (α=0.05 6 SEEBSy SEEIn SETIn. SETIn SETIn) p>0.05. p005 p p>0.05 (p>0.05) p<0.05. p<0.05 (p<0.05) service (BCa 1 (In α=0.0 α00 (α=0.0 p00 p>0.0 (p>0.05 p<0.0 (p<0.05 α=0. α0 (α=0. p0 p>0. (p>0.0 p<0. (p<0.0 α=0 (α=0 p>0 (p>0. p<0 (p<0. α= (α= p> (p>0 p< (p<0 (α (p> (p< (p

https://doi.org/10.1590/1678-7757-2022-0323

Diretriz Conjunta sobre Tromboembolismo Venoso – 2022
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Albricker, Ana Cristina Lopes

; Freire, Cláudia Maria Vilas

; Santos, Simone Nascimento dos

; Alcantara, Monica Luiza de

; Saleh, Mohamed Hassan

; Cantisano, Armando Luis

; Teodoro, José Aldo Ribeiro

; Porto, Carmen Lucia Lascasas

; Amaral, Salomon Israel do

; Veloso, Orlando Carlos Gloria

; Petisco, Ana Cláudia Gomes Pereira

; Barros, Fanilda Souto

; Barros, Márcio Vinícius Lins de

; Souza, Adriano José de

; Sobreira, Marcone Lima

; Miranda, Robson Barbosa de

; Moraes, Domingos de

; Verrastro, Carlos Gustavo Yuji

; Mançano, Alexandre Dias

; Lima, Ronaldo de Souza Leão

; Muglia, Valdair Francisco

; Matushita, Cristina Sebastião

; Lopes, Rafael Willain

; Coutinho, Artur Martins Novaes

; Pianta, Diego Bromfman

; Santos, Alair Augusto Sarmet Moreira Damas dos

; Naves, Bruno de Lima

; Vieira, Marcelo Luiz Campos

; Rochitte, Carlos Eduardo

Arquivos Brasileiros de Cardiologia

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apr 2022, Volume 118 N. 4 Pages 797 - 857

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

https://doi.org/10.36660/abc.20220213

Hepatocellular carcinoma (HCC) in patients with Non-Alcoholic Fatty Liver Disease (NAFLD): screening, treatment and survival analysis in a Brazilian series
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Alencar, Regiane Saraiva de Souza Melo

; Oliveira, Claudia P.

; Chagas, Aline Lopes

; Fonseca, Leonardo Gomes da

; Maccali, Claudia

; Saud, Lisa Rodrigues da Cunha

; Xerfan, Mariana Pinheiro

; Stefano, Jose Tadeu

; Herman, Paulo

; D'Albuquerque, Luiz Augusto Carneiro

; Alves, Venâncio Avancini Ferreira

; Carrilho, Flair Jose

Clinics

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2022, Volume 77 elocation 100097

Abstract: En | Text: En | PDF: En

Abstract Objective: The aim of the present study was to evaluate the clinical features, Hepatocellular Carcinoma (HCC) screening, treatment modalities, and Overall Survival (OS) in a series of Non-Alcoholic Fatty Liver Disease-Related Hepatocellular Carcinoma (NAFLD-HCC) Brazilian patients. Methods: This was a cross-sectional study at the Instituto do Cancer do Estado de São Paulo, at the Faculdade de Medicina da Universidade de São Paulo with the approval of the local research ethics committee. NAFLD patients with HCC diagnosed, from May 2010 to May 2019, were included. Results: A total of 131 patients were included. Risk factors for NAFLD were present in 94.7% of the patients. Only 29% of patients were in the HCC screening program before diagnosis. HCC treatment was performed in 84.7% of patients. Cumulative survival at the end of the first year was 72%, second-year 52%, and fifth-year 32%. HCC screening before diagnosis was not significantly associated with higher cumulative survival. The independent factors associated with shorter general survival were BCLC C-D, p < 0.001, and the size of the largest nodule > 42 mm, p = 0.039. Conclusions: Although the efficacy of screening in our population regarding overall survival was hampered due to the sample size (29% had screening), BCLC stages C‒D and the size of the largest nodule larger than 42 mm were identified as independent factors of worse prognosis.

https://doi.org/10.1016/j.clinsp.2022.100097

10.

Solar drying of 'Prata' bananas
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SILVA, Álvaro Gustavo Ferreira da

; CRUZ, Renata Ranielly Pedroza

; MOREIRA, Wennia Gomes

; PEREIRA, Maria Angelica Freitas

; SILVA, Adriano Sant'Ana

; COSTA, Franciscleudo Bezerra da

; NASCIMENTO, Ana Marinho do

; SOUZA, Pahlevi Augusto de

; TIMOTEO, André Luiz dos Santos

; RIBEIRO, Wellington Souto

Food Science and Technology

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2022, Volume 42 elocation e75021

Abstract: En | Text: En | PDF: En

Abstract The banana is one of the most consumed fruits in the world, but it has little shelf life due to its high water activity. Drying is able to increase shelf life and pre-treatments can optimize the process. The objective was to study the solar drying kinetics and evaluate the effect of pre-treatments on the drying kinetics and physico-chemical quality of 'Prata' bananas. The drying was carried out in a solar dryer and the pre-treatments consisted of immersing the samples in solutions of water, citric acid (1%) and lemon juice (10%). Water loss, drying kinetics, mathematical models and physical-chemical and colorimetric characteristics of fresh and dried bananas were evaluated. The drying rate was higher at the beginning and stabilized after 20 hours. The mathematical model of Midilli and Kucuk was the one that best fit the experimental data. The water content, ascorbic acid and the parameters L *, b *, C * and h ° reduced after drying. Reducing sugars and a * coordinate increased and the acidity was not changed with drying. The solar drying of 'Prata' bananas is a sustainable and economical way to make a product available with a longer shelf life.

https://doi.org/10.1590/fst.75021

11.

National Brazilian survey on the outcomes of hepatitis c retreatment in patients non-responders to direct antiviral agents
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Ferraz, Maria Lúcia Gomes

; Piccoli, Leonora de Zorzi

; Rezende, Rosamar

; Borba, Luiz Augusto

; Pissaia Junior, Alcindo

; Cheinquer, Hugo

; Silva, Giovanni Faria

; Ferreira, Paulo Roberto Abrão

; Villela-Nogueira, Cristiane Alves

; Mazo, Daniel Ferraz

; Souza, Fernanda Fernandes

; Codes, Liana

; Ivantes, Claudia Alexandra Pontes

; Gomide, Geisa Perez Medina

; Pereira, Gustavo Henrique Santos

; Pessôa, Mário Guimarães

; França, Alex Vianey Callado

; Pinto, Arlene dos Santos

; Teixeira, Rosângela

; Bittencourt, Paulo Lisboa

Brazilian Journal of Infectious Diseases

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2022, Volume 26 N. 4 elocation 102388

Abstract: En | Text: En | PDF: En

ABSTRACT Background and aims: Treatment of hepatitis C with direct antiviral agents (DAA) is associated with almost 95% of sustained virological response. However, some patients need retreatment. In Brazil, it should be done according to the Ministry of Health guidelines, frequently updated to include newly available drugs. This study aimed to conduct a national survey about the characteristics and outcomes of retreatment of hepatitis C in previously non-responders to DAAs. Patients and methods: Institutions from all over the country were invited to participate in a national registry for retreatment, including information about clinical and epidemiological characteristics of the patients, type and outcomes of retreatment regimens. Only patients previously treated with interferon-free regimens were included. Results: As previous treatments the distribution was: SOF/DCV (56%), SOF/SIM (22%), 3D (11%), SOF/LED (6%) and SOF/RBV (5%). For retreatment the most frequently used drugs were SOF/GP (46%), SOF/DCV (23%) and SOF/VEL (11%). From 159 patients retreated, 132/159 (83%) had complete information in the registry and among them only seven patients were non-responders (SVR of 94.6%). All retreatments were well tolerated, without any serious adverse events or interruptions. Conclusion: The retreatment of patients previously non-responders to DAAs was associated with high rate of SVR in this sample of Brazilian patients. This finding allows us to conclude that the retreatment options available in the public health system in Brazil are effective and safe and are an important component of the strategy of elimination of hepatitis C in our country.

https://doi.org/10.1016/j.bjid.2022.102388

12.

Diretrizes da Sociedade Brasileira de Cardiologia sobre Angina Instável e Infarto Agudo do Miocárdio sem Supradesnível do Segmento ST – 2021
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Nicolau, José Carlos

; Feitosa Filho, Gilson Soares

; Petriz, João Luiz

; Furtado, Remo Holanda de Mendonça

; Précoma, Dalton Bertolim

; Lemke, Walmor

; Lopes, Renato Delascio

; Timerman, Ari

; Marin Neto, José A.

; Bezerra Neto, Luiz

; Gomes, Bruno Ferraz de Oliveira

; Santos, Eduardo Cavalcanti Lapa

; Piegas, Leopoldo Soares

; Soeiro, Alexandre de Matos

; Negri, Alexandre Jorge de Andrade

; Franci, Andre

; Markman Filho, Brivaldo

; Baccaro, Bruno Mendonça

; Montenegro, Carlos Eduardo Lucena

; Rochitte, Carlos Eduardo

; Barbosa, Carlos José Dornas Gonçalves

; Virgens, Cláudio Marcelo Bittencourt das

; Stefanini, Edson

; Manenti, Euler Roberto Fernandes

; Lima, Felipe Gallego

; Monteiro Júnior, Francisco das Chagas

; Correa Filho, Harry

; Pena, Henrique Patrus Mundim

; Pinto, Ibraim Masciarelli Francisco

; Falcão, João Luiz de Alencar Araripe

; Sena, Joberto Pinheiro

; Peixoto, José Maria

; Souza, Juliana Ascenção de

; Silva, Leonardo Sara da

; Maia, Lilia Nigro

; Ohe, Louis Nakayama

; Baracioli, Luciano Moreira

; Dallan, Luís Alberto de Oliveira

; Dallan, Luis Augusto Palma

; Mattos, Luiz Alberto Piva e

; Bodanese, Luiz Carlos

; Ritt, Luiz Eduardo Fonteles

; Canesin, Manoel Fernandes

; Rivas, Marcelo Bueno da Silva

; Franken, Marcelo

; Magalhães, Marcos José Gomes

; Oliveira Júnior, Múcio Tavares de

; Filgueiras Filho, Nivaldo Menezes

; Dutra, Oscar Pereira

; Coelho, Otávio Rizzi

; Leães, Paulo Ernesto

; Rossi, Paulo Roberto Ferreira

; Soares, Paulo Rogério

; Lemos Neto, Pedro Alves

; Farsky, Pedro Silvio

; Cavalcanti, Rafael Rebêlo C.

; Alves, Renato Jorge

; Kalil, Renato Abdala Karam

; Esporcatte, Roberto

; Marino, Roberto Luiz

; Giraldez, Roberto Rocha Corrêa Veiga

; Meneghelo, Romeu Sérgio

; Lima, Ronaldo de Souza Leão

; Ramos, Rui Fernando

; Falcão, Sandra Nivea dos Reis Saraiva

; Dalçóquio, Talia Falcão

; Lemke, Viviana de Mello Guzzo

; Chalela, William Azem

; Mathias Júnior, Wilson

Arquivos Brasileiros de Cardiologia

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jul 2021, Volume 117 N. 1 Pages 181 - 264

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

https://doi.org/10.36660/abc.20210180 3052 downloads

13.

Diretrizes Brasileiras de Hipertensão Arterial – 2020
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Barroso, Weimar Kunz Sebba

; Rodrigues, Cibele Isaac Saad

; Bortolotto, Luiz Aparecido

; Mota-Gomes, Marco Antônio

; Brandão, Andréa Araujo

; Feitosa, Audes Diógenes de Magalhães

; Machado, Carlos Alberto

; Poli-de-Figueiredo, Carlos Eduardo

; Amodeo, Celso

; Mion Júnior, Décio

; Barbosa, Eduardo Costa Duarte

; Nobre, Fernando

; Guimarães, Isabel Cristina Britto

; Vilela-Martin, José Fernando

; Yugar-Toledo, Juan Carlos

; Magalhães, Maria Eliane Campos

; Neves, Mário Fritsch Toros

; Jardim, Paulo César Brandão Veiga

; Miranda, Roberto Dischinger

; Póvoa, Rui Manuel dos Santos

; Fuchs, Sandra C

; Alessi, Alexandre

; Lucena, Alexandre Jorge Gomes de

; Avezum, Alvaro

; Sousa, Ana Luiza Lima

; Pio-Abreu, Andrea

; Sposito, Andrei Carvalho

; Pierin, Angela Maria Geraldo

; Paiva, Annelise Machado Gomes de

; Spinelli, Antonio Carlos de Souza

; Nogueira, Armando da Rocha

; Dinamarco, Nelson

; Eibel, Bruna

; Forjaz, Cláudia Lúcia de Moraes

; Zanini, Claudia Regina de Oliveira

; Souza, Cristiane Bueno de

; Souza, Dilma do Socorro Moraes de

; Nilson, Eduardo Augusto Fernandes

; Costa, Elisa Franco de Assis

; Freitas, Elizabete Viana de

; Duarte, Elizabeth da Rosa

; Muxfeldt, Elizabeth Silaid

; Lima Júnior, Emilton

; Campana, Erika Maria Gonçalves

; Cesarino, Evandro José

; Marques, Fabiana

; Argenta, Fábio

; Consolim-Colombo, Fernanda Marciano

; Baptista, Fernanda Spadotto

; Almeida, Fernando Antonio de

; Borelli, Flávio Antonio de Oliveira

; Fuchs, Flávio Danni

; Plavnik, Frida Liane

; Salles, Gil Fernando

; Feitosa, Gilson Soares

; Silva, Giovanio Vieira da

; Guerra, Grazia Maria

; Moreno Júnior, Heitor

; Finimundi, Helius Carlos

; Back, Isabela de Carlos

; Oliveira Filho, João Bosco de

; Gemelli, João Roberto

; Mill, José Geraldo

; Ribeiro, José Marcio

; Lotaif, Leda A. Daud

; Costa, Lilian Soares da

; Magalhães, Lucélia Batista Neves Cunha

; Drager, Luciano Ferreira

; Martin, Luis Cuadrado

; Scala, Luiz César Nazário

; Almeida, Madson Q.

; Gowdak, Marcia Maria Godoy

; Klein, Marcia Regina Simas Torres

; Malachias, Marcus Vinícius Bolívar

; Kuschnir, Maria Cristina Caetano

; Pinheiro, Maria Eliete

; Borba, Mario Henrique Elesbão de

; Moreira Filho, Osni

; Passarelli Júnior, Oswaldo

; Coelho, Otavio Rizzi

; Vitorino, Priscila Valverde de Oliveira

; Ribeiro Junior, Renault Mattos

; Esporcatte, Roberto

; Franco, Roberto

; Pedrosa, Rodrigo

; Mulinari, Rogerio Andrade

; Paula, Rogério Baumgratz de

; Okawa, Rogério Toshiro Passos

; Rosa, Ronaldo Fernandes

; Amaral, Sandra Lia do

; Ferreira-Filho, Sebastião R.

; Kaiser, Sergio Emanuel

; Jardim, Thiago de Souza Veiga

; Guimarães, Vanildo

; Koch, Vera H.

; Oigman, Wille

; Nadruz, Wilson

Arquivos Brasileiros de Cardiologia

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mar 2021, Volume 116 N. 3 Pages 516 - 658

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

https://doi.org/10.36660/abc.20201238 10948 downloads

14.

Study of delays in constructions: a managerial point of view of private companies in Brasilia, Brazil
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Almeida, Eduardo Lavocat Galvão de

; Feitoza, Vitor Amadeu da Silva

; Carvalho, Michele Tereza Marques

; Piña, Ana Beatriz Souza

; Araújo, Lissa Gomes

; Aidar, Luiz Augusto Gimenez

Gestão & Produção

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2021, Volume 28 N. 3 elocation e5194

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Atrasos são um dos problemas mais recorrentes na indústria da construção, causas de consequências negativas em projetos de construção e, muitas vezes, motivo principal de fracassos de projetos. Ainda existe a necessidade de estudar as causas dos atrasos em obras de construção. O objetivo deste trabalho é determinar as causas mais influentes nos atrasos dos projetos de construção civil da indústria privada, colaborando com a lista acadêmica geral das causas dos atrasos na construção civil. Uma lista com 24 causas foi compilada e submetida como questionário para 47 profissionais em papéis administrativos em obras do setor privado da construção. Os resultados foram processados por meio do Índice de Importância Relativa (Relative Importance Index – RII). As causas mais importantes de atraso foram: retrabalho, baixa produtividade da mão-de-obra, falta de mão-de-obra qualificada, e mudanças de projeto. Os resultados indicam que existem diferenças significativas entre as opiniões dos profissionais de diferentes posições hierárquicas. As contribuições mais significativas desse estudo são que as causas dos atrasos na construção variam dependendo dos profissionais em cada nível hierárquico da obra, demonstrando a importância de entender o problema em prol de uma visão sistêmica e profunda do fenômeno.

Abstract Delay is one of the most recurrent problems in the construction industry. It is the cause of major negative consequences on construction projects and it can be the main reason for project failures. Still, there is a need for studies focusing on causes of these delays. The objective of this article is to determine the factors with greatest influence on the backlog of real estate developments, improving the collective list of causes of delays in construction projects. A list of 24 probable causes was assembled and submitted as a survey for 47 professionals in administrative rolls from the building construction sector, more precisely, from private companies. The results were processed utilizing the Relative Importance Index (RII) ranking approach. The outcome shows that the most important delay causes are: rework, poor labor productivity, lack of qualified labor, unqualified labor, and project changes. The results also indicate that there are significant differences of opinion between the professionals of distinct hierarchy positions. The results obtained indicate that there is a transition between the opinions of professionals in different roles regarding the importance of influential factors in the delay of works, according to the managerial level of each group.

https://doi.org/10.1590/1806-9649-2021v28e5194

15.

Use of biofermented plants adapted to the semi-arid region in piglet diets
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OLIVEIRA, Elton Roger Alves de

; MARTINS, Terezinha Domiciano

; THOMAZ, Maria Cristina

; PASCOAL, Leonardo Augusto Fonseca

; SILVA, José Humberto Vilar da

; SILVA, Taisa Rocha Gomes da

; BRITO, Mariany de Souza

; ALMEIDA, Jonathan Mádson dos Santos

; ALMEIDA, Jorge Luiz Santos de

Revista Brasileira de Saúde e Produção Animal

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2021, Volume 22 elocation e2122072021

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Foram realizados dois ensaios experimentais para avaliar a inclusão de biofermentado a base de plantas do semiárido na dieta de leitões na fase inicial. No ensaio I foi avaliado o valor nutricional e a digestibilidade dos nutrientes e os valores de energia digestível e metabolizável do biofermentado. Para tanto, foram utilizados oito leitões com peso médio inicial de 15,2 ± 2,7 kg, alojados em gaiolas de metabolismo, utilizou-se o método de coleta total de fezes e urina. O biofermentado apresentou 80,40% e 68,18% como coeficientes de digestibilidade para a matéria seca e fibra bruta, respectivamente; 10,08% de proteína bruta e 2.865 kcal/kg de energia metabolizável. No segundo ensaio foi avaliada a inclusão de 0; 3; 6 e 9% de biofermentado sobre o desempenho, incidência de diarreia, componentes plasmáticos, peso e comprimento de órgãos digestivos de leitões na fase inicial. Para tanto, foram utilizados 40 leitões com peso médio inicial de 12,6±3,5 kg, distribuídos em delineamento em blocos casualizados com quatro tratamentos, cinco repetições e dois animais por unidade experimental. A inclusão dos diferentes níveis de biofermentado não afetou (P>0,05) o desempenho, o peso e comprimento dos órgãos digestivos e parâmetros séricos. No entanto, a inclusão do biofermentado reduziu (P<0,01) a incidência de diarreia. Conclui-se que o biofermentado a base de plantas adaptadas ao semiárido apresenta potencial de ser utilizado em dietas para suínos na fase inicial.

ABSTRACT Two experimental tests were carried out to evaluate the inclusion of a biofermented semi-arid plant mix in diets of piglets in the initial weaning phase. In the first trial, the nutritional value and digestibility of nutrients and the digestible and metabolizable energy values of the bio-fermented plants mix were evaluated. To do so, eight piglets with an initial average weight of 15.2 ± 2.7 kg were used, housed in metabolic cages, and using the total collection of feces and urine. The bio-fermented plant mix diet presented 80.40% and 68.18% as digestibility coefficients for dry matter and crude fiber, respectively; 10.08% crude protein and 2,865 kcal/kg of metabolizable energy. In the second trial, the inclusion of 0, 3, 6 and 9% of bio-fermented plant mix was evaluated on performance, diarrhea incidence, plasma components, weight, and length of digestive organs of piglets in the initial weaning phase. To do so, 40 piglets with an initial average weight of 12.6 ± 3.5 kg were used, distributed in a randomized block design with four treatments, five replicates, and two animals per experimental unit. The inclusion of different levels of bio-fermented plant mix did not affect (P>0.05) the performance, weight, and length of digestive organs or serum parameters. However, the inclusion of bio-fermented plant reduced (P<0.01) the diarrhea incidence. It is concluded that bio-fermented plants adapted to the semi-arid region has the potential to be used in diets for pigs in the initial weaning phase.

https://doi.org/10.1590/s1519-99402122072021 218 downloads

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