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Abstract Background Patients with immune-mediated rheumatic diseases (IMRDs) have been prioritized for COVID-19 vaccination to mitigate the infection severity risks. Patients with rheumatoid arthritis (RA) are at a high risk of severe COVID-19 outcomes, especially those under immunosuppression or with associated comorbidities. However, few studies have assessed the safety of the COVID-19 vaccine in patients with RA. Objective To evaluate the safety of vaccines against SARS-CoV-2 in patients with RA. Methods This data are from the study “Safety and Efficacy on COVID-19 Vaccine in Rheumatic Diseases,” a Brazilian multicentric prospective phase IV study to evaluate COVID-19 vaccine in IMRDs in Brazil. Adverse events (AEs) in patients with RA of all centers were assessed after two doses of ChAdOx1 (Oxford/AstraZeneca) or CoronaVac (Sinovac/Butantan). Stratification of postvaccination AEs was performed using a diary, filled out daily and returned at the end of 28 days for each dose. Results A total of 188 patients with RA were include, 90% female. CoronaVac was used in 109 patients and ChAdOx1 in 79. Only mild AEs were observed, mainly after the first dose. The most common AEs after the first dose were pain at the injection (46,7%), headache (39,4%), arthralgia (39,4%), myalgia (30,5%) and fatigue (26,6%), and ChAdOx1 had a higher frequency of pain at the injection (66% vs 32 %, p < 0.001) arthralgia (62% vs 22%, p < 0.001) and myalgia (45% vs 20%, p < 0.001) compared to CoronaVac. The more common AEs after the second dose were pain at the injection (37%), arthralgia (31%), myalgia (23%), headache (21%) and fatigue (18%). Arthralgia (41,4% vs 25%, p = 0.02) and pain at injection (51,4% vs 27%, p = 0.001) were more common with ChAdOx1. No serious AEs were related. With Regard to RA activity level, no significant difference was observed between the three time periods for both COVID-19 vaccines. Conclusion In the comparison between the two immunizers in patients with RA, local reactions and musculoskeletal symptoms were more frequent with ChAdOx1 than with CoronaVac, especially after the first dose. In summary, the AE occurred mainly after the first dose, and were mild, like previous data from others immunizing agents in patients with rheumatoid arthritis. Vaccination did not worsen the degree of disease activity. immunemediated immune mediated (IMRDs COVID19 COVID 19 COVID-1 risks (RA outcomes comorbidities However SARSCoV2 SARSCoV SARS CoV 2 SARS-CoV- Safety Diseases, Diseases Brazil (AEs ChAdOx Oxford/AstraZeneca OxfordAstraZeneca Oxford AstraZeneca (Oxford/AstraZeneca Sinovac/Butantan. SinovacButantan Sinovac/Butantan . Sinovac Butantan (Sinovac/Butantan) diary 18 include 90 female 10 79 46,7%, 467 46,7% , 46 7 (46,7%) 39,4%, 394 39,4% 39 4 (39,4%) 30,5% 305 30 5 (30,5% 26,6%, 266 26,6% 26 6 (26,6%) 66% 66 (66 3 % 0.001 0001 0 001 62% 62 (62 22 22% 45% 45 (45 20 20% 37%, 37 37% (37%) 31%, 31 31% (31%) 23%, 23 23% (23%) 21% 21 (21% 18%. 18% (18%) 41,4% 414 41 (41,4 25 25% 0.02 002 02 51,4% 514 51 (51,4 27 27% related level summary COVID1 1 COVID- SARS-CoV (Sinovac/Butantan 9 46,7 (46,7% 39,4 (39,4% 30,5 (30,5 26,6 (26,6% (6 0.00 000 00 (4 (37% (31% (23% (21 (18% 41,4 (41, 0.0 51,4 (51, 46, (46,7 39, (39,4 30, (30, 26, (26,6 ( (37 (31 (23 (2 (18 41, (41 0. 51, (51 (46, (39, (30 (26, (3 (1 (5 (46 (39 (26

https://doi.org/10.1186/s42358-024-00397-5

Ketogenic therapy in childhood and adolescence: recommendations of the Brazilian experts group adolescence
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de Brito Sampaio, Letícia Pereira

; Henriques-Souza, Adélia Maria de Miranda

; Lin, Katia

; Neri, Lenycia de Cassya Lopes

; Inuzuka, Luciana Midori

; Uchôa, Ludmila Inácio de Lima

; Gregório, Marcela Marques de Oliveira

; Guilhoto, Laura Maria

; Montenegro, Maria Augusta

; Lunardi, Mariana

; Veiga, Marielza

; de Lima, Patricia Azevedo

; Braatz, Vera

Arquivos de Neuro-Psiquiatria

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jun 2023, Volume 81 N. 6 Pages 597 - 606

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo As terapias dietéticas cetogênicas (TDC) são um tratamento seguro e eficaz para epilepsia farmacorresistente em crianças. Existem quatro tipos principais de TDCs: a dieta cetogênica (DC) clássica, a dieta de Atkins modificada (DAM), a dieta de triglicerídeos de cadeia média (DTCM) e a dieta de baixo índice glicêmico (DBIG). O Grupo Internacional de Estudos de Dietas Cetogênicas (International Ketogenic Diet Study Group) propõe recomendações para o manejo da DC em crianças com epilepsia. No entanto, faltam diretrizes que contemplem as necessidades específicas da população brasileira. Assim, a Associação Brasileira de Neurologia Infantil elaborou essas recomendações com o objetivo de estimular e expandir o uso da DC no Brasil. TDC (TDC TDCs (DC clássica DAM, DAM , (DAM) DTCM (DTCM DBIG. DBIG . (DBIG) International Group entanto brasileira Assim Brasil (DAM (DBIG

Abstract Ketogenic dietary therapies (KDTs) are a safe and effective treatment for pharmacoresistant epilepsy in children. There are four principal types of KDTs: the classic KD, the modified Atkins diet (MAD), the medium-chain triglyceride (MCT) diet, and the low glycemic index diet (LGID). The International Ketogenic Diet Study Group recommends managing KDTs in children with epilepsy. However, there are no guidelines that address the specific needs of the Brazilian population. Thus, the Brazilian Child Neurology Association elaborated on these recommendations with the goal of stimulating and expanding the use of the KD in Brazil. (KDTs MAD, MAD , (MAD) mediumchain medium chain MCT (MCT LGID. LGID . (LGID) However population Thus Brazil (MAD (LGID

https://doi.org/10.1055/s-0043-1768676

Correlation between symptoms of depression, attitude, and self-care in elderly with type 2 diabetes depression attitude selfcare self care
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Frazão, Maria Cristina Lins Oliveira

; Viana, Lia Raquel de Carvalho

; Ferreira, Gerlania Rodrigues Salviano

; Pimenta, Cláudia Jeane Lopes

; Silva, Cleane Rosa Ribeiro da

; Madruga, Kaisy Martins de Albuquerque

; Batista, Patrícia Serpa de Souza

; Costa, Kátia Neyla de Freitas Macedo

Revista Brasileira de Enfermagem

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2023, Volume 76 N. 3 elocation e20220741

Abstract: Es En Pt | Text: Es En Pt | PDF: Es | PDF: En | PDF: Pt

RESUMEN Objetivos: correlacionar síntomas depresivos, actitud y autocuidado de personas ancianas con diabetes tipo 2. Métodos: estudio desarrollado con 144 ancianos con diabetes; realizado en Unidades de Salud de la Familia. Utilizados instrumento semiestructurado para obtener los datos referentes al perfil sociodemográfico, Escala de Depresión Geriátrica (15 ítems), Encuesta de Actitudes Psicológicas del Diabetes y de Actividades de Autocuidado con el Diabetes. Resultados: identificado que 24,3% de los participantes presentaron sintomatología depresiva; y 93,8%, actitudes negativas de enfrentamiento. Observado una mayor adhesión a las actividades de autocuidado relacionadas a la práctica medicamentosa. En la correlación entre las escalas, fue percibida una correspondencia negativa e inversamente proporcional entre sintomatología depresiva y actividad física (p=0,010) y cuidado con los pies (p=0,006), igualmente entre actitud y cuidado con los pies (p=0,009). Conclusiones: el autocuidado en personas ancianas con diabetes mellitus sufre influencia de los síntomas depresivos y de la actitud negativa en el enfrentamiento. Objetivos 2 Métodos 14 Familia sociodemográfico 15 (1 ítems, ítems , ítems) Resultados 243 24 3 24,3 938 93 8 93,8% enfrentamiento medicamentosa escalas p=0,010 p0010 p 0 010 (p=0,010 p=0,006, p0006 p=0,006 006 (p=0,006) p=0,009. p0009 p=0,009 . 009 (p=0,009) Conclusiones 1 ( 24, 9 93,8 p=0,01 p001 01 (p=0,01 p000 p=0,00 00 (p=0,006 (p=0,009 93, p=0,0 p00 (p=0,0 (p=0,00 p=0, p0 (p=0, p=0 (p=0 p= (p= (p

ABSTRACT Objectives: to correlate depressive symptoms, attitude, and self-care of elderly people with type 2 diabetes. Methods: study developed with 144 elderly people with diabetes; carried out in Family Health Units. A semi-structured instrument was used to obtain data on the sociodemographic profile; the Geriatric Depression Scale (15 items), the Questionário de Atitudes Psicológicas do Diabetes [Psychological Attitudes of Diabetes Questionnaire], and the Diabetes Self-Care Activities Questionnaire (DSCA) were also used. Results: it was identified that 24.3% of the participants presented depressive symptoms, and 93.8% presented negative attitudes of coping. A greater adherence to self-care activities related to the practice of medication was observed. In the correlation between the scales, a negative and inversely proportional correspondence was noted between depressive symptomatology and physical activity (p=0.010) and foot care (p=0.006), likewise between attitude and foot care (p=0.009). Conclusions: self-care in elderly people with diabetes mellitus is influenced by depressive symptoms and negative coping attitudes. Objectives selfcare self Methods 14 Units semistructured semi structured profile 15 (1 items, items , items) Psychological Questionnaire, Questionnaire] SelfCare Self Care DSCA (DSCA Results 243 24 3 24.3 938 93 8 93.8 observed scales p=0.010 p0010 p 0 010 (p=0.010 p=0.006, p0006 p=0.006 006 (p=0.006) p=0.009. p0009 p=0.009 . 009 (p=0.009) Conclusions 1 ( 24. 9 93. p=0.01 p001 01 (p=0.01 p000 p=0.00 00 (p=0.006 (p=0.009 p=0.0 p00 (p=0.0 (p=0.00 p=0. p0 (p=0. p=0 (p=0 p= (p= (p

RESUMO Objetivos: correlacionar sintomas depressivos, atitude e autocuidado de pessoas idosas com diabetes tipo 2. Métodos: estudo desenvolvido com 144 pessoas idosas com diabetes; realizado em Unidades de Saúde da Família. Utilizaram-se instrumento semiestruturado para obter os dados referentes ao perfil sociodemográfico, a Escala de Depressão Geriátrica (15 itens), o Questionário de Atitudes Psicológicas do Diabetes e o de Atividades de Autocuidado com o Diabetes. Resultados: identificou-se que 24,3% dos participantes apresentaram sintomatologia depressiva; e 93,8%, atitudes negativas de enfrentamento. Observou-se uma maior adesão às atividades de autocuidado relacionadas à prática medicamentosa. Na correlação entre as escalas, foi percebida uma correspondência negativa e inversamente proporcional entre sintomatologia depressiva e atividade física (p=0,010) e cuidado com os pés (p=0,006), do mesmo modo entre atitude e cuidado com os pés (p=0,009). Conclusões: o autocuidado em pessoas idosas com diabetes mellitus sofre influência dos sintomas depressivos e da atitude negativa no enfrentamento. Objetivos 2 Métodos 14 Família Utilizaramse Utilizaram se sociodemográfico 15 (1 itens, itens , itens) Resultados identificouse identificou 243 24 3 24,3 938 93 8 93,8% enfrentamento Observouse Observou medicamentosa escalas p=0,010 p0010 p 0 010 (p=0,010 p=0,006, p0006 p=0,006 006 (p=0,006) p=0,009. p0009 p=0,009 . 009 (p=0,009) Conclusões 1 ( 24, 9 93,8 p=0,01 p001 01 (p=0,01 p000 p=0,00 00 (p=0,006 (p=0,009 93, p=0,0 p00 (p=0,0 (p=0,00 p=0, p0 (p=0, p=0 (p=0 p= (p= (p

https://doi.org/10.1590/0034-7167-2022-0741

Prevalence of subclinical systolic dysfunction in Takayasu's arteritis and its association with disease activity: a cross-sectional study Takayasus Takayasu s activity crosssectional cross sectional
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Figueiroa, Maria de Lourdes Castro de Oliveira

; Costa, Maria Carolina Moura

; Costa, Maria Clara Moura

; Lobo, Paulo Rocha

; Sanches, Leonardo Vinicius

; Martins, Katia Maria Alves

; Sousa, Anna Paula Mota Duque

; Pedreira, Ana Luisa Souza

; Santiago, Mittermayer Barreto

Advances in Rheumatology

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2023, Volume 63 elocation 41

Abstract: En | Text: En | PDF: En

Abstract Background Takayasu's arteritis (TA) is a vasculitis that affects the aorta and its branches and causes stenosis, occlusion, and aneurysms. Up to 60% of TA patients are associated with cardiac involvement which confers a poor prognosis. Global longitudinal strain (GLS) analysis is an echocardiographic technique that can detect the presence of subclinical systolic dysfunction. Hence, this study aimed to describe the prevalence of subclinical systolic dysfunction in patients with TA using the GLS method and to correlate this finding with disease activity using the ITAS-2010 (Indian Takayasu Activity Score). Methods Thirty patients over 18 years of age who met the American College of Rheumatology (ACR) 1990 criteria for TA were included. The sample was submitted for medical record review, clinical and echocardiographic evaluation, and application of ITAS-2010. The cutoff for systolic dysfunction was GLS > - 20%. Results Of the 30 patients analyzed, 25 (83.3%) were female, and the mean age was 42.6 years (± 13.2). The median time since diagnosis was 7.5 years [range, 3-16.6 years], and the type V angiographic classification was the most prevalent (56.7%). Regarding echocardiographic findings, the median ejection fraction (EF) was 66% [61-71%] and the GLS was - 19.5% [-21.3 to -15.8%]. Although half of the participants had reduced GLS, only two had reduced EF. Eleven patients (33.%) met the criteria for activity. An association was found between disease activity and reduced GLS in eight patients (P = 0.02) using the chi-square test. Conclusion GLS seems to be an instrument capable of the early detection of systolic dysfunction in TA. The association between GLS and disease activity in this study should be confirmed in a study with a larger sample size. Takayasus s (TA stenosis occlusion aneurysms 60 prognosis (GLS Hence ITAS2010 ITAS 2010 ITAS-201 Indian Score. Score . Score) 1 ACR (ACR 199 included review evaluation ITAS2010. 2010. 20 20% 3 analyzed 2 83.3% 833 83 (83.3% female 426 42 6 42. ± ( 13.2. 132 13.2 13 13.2) 75 7 5 7. range, range [range 316.6 3166 16.6 16 3-16. years, , years] 56.7%. 567 56.7% 56 (56.7%) findings EF (EF 66 6171% 6171 61 71% 71 [61-71% 195 19 19.5 21.3 213 21 [-21. 15.8%. 158 15.8% 15 8 -15.8%] 33.% 33 (33.% P 0.02 002 0 02 chisquare chi square test size ITAS201 201 ITAS-20 83.3 (83.3 4 13. 316 316. 166 16. 3-16 56.7 (56.7% 617 [61-71 19. 21. [-21 15.8 -15.8% 33. (33. 0.0 00 ITAS20 ITAS-2 83. (83. 31 3-1 56. (56.7 [61-7 [-2 15. -15.8 (33 0. ITAS2 ITAS- (83 3- (56. [61- [- -15. (3 (8 (56 [61 [ -15 (5 [6 -1

https://doi.org/10.1186/s42358-023-00322-2

Does religiosity impact binge drinking among early adolescents? A cross-sectional study in a city in Southeastern Brazil
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Guimarães, Mariana Oliveira

; Guimarães, Gilberto de Lima

; Silva, Jessica Walewska Rodrigues da

; Souza, Kátia Kely Bragança de

; Vieira-Andrade, Raquel Gonçalves

; Ferreira, Raquel Conceição

; Zarzar, Patrícia Maria Pereira de Araújo

Ciência & Saúde Coletiva

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sep 2022, Volume 27 N. 9 Pages 3669 - 3678

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo O objetivo do estudo foi avaliar a associação entre religiosidade e binge drinking no início da adolescência. Um estudo transversal realizado com adolescentes de 10 a 13 anos de Belo Horizonte, Brasil. Foi realizada uma amostragem aleatória estratificada considerando distrito administrativo e ano escolar. Os adolescentes preencheram um formulário com o AUDIT C, perguntas sobre religiosidade e perguntas sobre binge drinking pelos pais e melhor amigo. Um formulário sobre questões socioeconômicas foi respondido pelos responsáveis. Foi realizada análise descritiva, regressão logística univariada e multivariada. Participaram do estudo 650 adolescentes. A frequência de binge drinking foi de 13,7%. No modelo ajustado, a religiosidade não esteve associada ao binge drinking. As covariáveis associadas foram idade de 12-13 anos (OR: 1,94 IC95%: 1,06-3,56; p=0,030), binge drinking pela mãe (OR: 3,12; IC95%: 1,76-5,52; p<0,001) binge drinking pelo melhor amigo (OR: 6,01; IC95%: 3,40-10,62; p<0,001) e família não nuclear (OR: 1,80; IC95%: 1,01-3,23; p=0,045). Os achados revelaram que apesar dos adolescentes afirmarem serem religiosos, para o binge drinking, os principais fatores que influenciaram essa decisão foi o binge drinking pelo melhor amigo, mãe e família não nuclear.

Abstract This study evaluated the association between religiosity and binge drinking in early adolescence. A cross-sectional study was conducted with adolescents aged 10-13 from Belo Horizonte, Brazil. Stratified random sampling was performed considering the administrative district and school year. Adolescents filled an AUDIT-C form, containing questions about religiosity and binge drinking by parents and their best friends. Adolescents’ caregivers answered a form regarding socioeconomic issues. Descriptive analysis, univariate, and multivariate logistic regression were performed. A total of 650 adolescents participated in the study. The frequency of binge drinking was 13.7%. In the adjusted model, religiosity was not associated with binge drinking. The covariates associated were the age of 12-13 years (OR: 1.94; CI95%: 1.06-3.56; p=0.030), maternal binge drinking (OR: 3.12; CI95%: 1.76-5.52; p<0.001) best friend binge drinking (OR: 6.01; CI95%: 3.40-10.62; p<0.001) and nonnuclear family (OR: 1.80; CI95%: 1.01-3.23; p=0.045). The findings revealed that, for binge drinking, the main factors that influenced this decision were the best friend and maternal binge drinking and family structure, although the adolescents claimed to be religious.

https://doi.org/10.1590/1413-81232022279.03162022

Does religiosity impact binge drinking among early adolescents? A cross-sectional study in a city in Southeastern Brazil
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Guimarães, Mariana Oliveira

; Guimarães, Gilberto de Lima

; Silva, Jessica Walewska Rodrigues da

; Souza, Kátia Kely Bragança de

; Vieira-Andrade, Raquel Gonçalves

; Ferreira, Raquel Conceição

; Zarzar, Patrícia Maria Pereira de Araújo

Ciência & Saúde Coletiva

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sep 2022, Volume 27 N. 9 Pages 3669 - 3678

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

https://doi.org/10.1590/1413-81232022279.03162022

Acute micro-outbreak of Chagas disease in the southeastern Amazon: a report of five cases
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Brito, Andreza Karoline Souza Barros de

; Sousa, Débora Raysa Teixeira de

; Silva Junior, Edson Fidelis da

; Ruiz, Helton Jardys da Silva

; Arcanjo, Ana Ruth Lima

; Ortiz, Jessica Vanina

; Brito, Sabrina Silva de

; Jesus, Denison Vital

; Lima, Jorge Rubens Coelho de

; Couceiro, Kátia do Nascimento

; Silva, Mônica Regina Hosannah da Silva e

; Ferreira, João Marcos Bemfica Barbosa

; Guerra, Jorge Augusto Oliveira

; Guerra, Maria das Graças Vale Barbosa

Revista da Sociedade Brasileira de Medicina Tropical

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2022, Volume 55 elocation e0687-2021

Abstract: En | Text: En | PDF: En

ABSTRACT Background: Chagas disease is gaining importance in the Brazilian Amazon region as a differential diagnosis of febrile syndrome. The most recent microoutbreak occurred in Ipixuna, in Amazonas state. Methods: An epidemiological survey was conducted using parasitological and serological tests, and electrocardiographic analysis. Results: The patients belonged to one family and had ingested açaí acquired from Ipixuna. All patients reported fever and initially a thick blood smear test was done to identify Trypanosoma cruzi. Benznidazole treatment was administered to all patients. Conclusions: Knowledge of the epidemiological dynamics of Chagas disease allows us to improve control and management measures for this disease.

https://doi.org/10.1590/0037-8682-0687-2021

Práticas de ressuscitação volêmica em unidades de terapia intensiva brasileiras: uma análise secundária do estudo Fluid-TRIPS
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Freitas, Flavio Geraldo Rezende de

; Hammond, Naomi

; Li, Yang

; Azevedo, Luciano Cesar Pontes de

; Cavalcanti, Alexandre Biasi

; Taniguchi, Leandro

; Gobatto, André

; Japiassú, André Miguel

; Bafi, Antonio Tonete

; Mazza, Bruno Franco

; Noritomi, Danilo Teixeira

; Dal-Pizzol, Felipe

; Bozza, Fernando

; Salluh, Jorge Ibrahin Figueira

; Westphal, Glauco Adrieno

; Soares, Márcio

; Assunção, Murillo Santucci César de

; Lisboa, Thiago

; Lobo, Suzana Margarete Ajeje

; Barbosa, Achilles Rohlfs

; Ventura, Adriana Fonseca

; Souza, Ailson Faria de

; Silva, Alexandre Francisco

; Toledo, Alexandre

; Reis, Aline

; Cembranel, Allan

; Rea Neto, Alvaro

; Gut, Ana Lúcia

; Justo, Ana Patricia Pierre

; Santos, Ana Paula

; Albuquerque, André Campos D. de

; Scazufka, André

; Rodrigues, Antonio Babo

; Fernandino, Bruno Bonaccorsi

; Silva, Bruno Goncalves

; Vidal, Bruno Sarno

; Pinheiro, Bruno Valle

; Pinto, Bruno Vilela Costa

; Feijo, Carlos Augusto Ramos

; Abreu Filho, Carlos de

; Bosso, Carlos Eduardo da Costa Nunes

; Moreira, Carlos Eduardo Nassif

; Ramos, Carlos Henrique Ferreira

; Tavares, Carmen

; Arantes, Cidamaiá

; Grion, Cintia

; Mendes, Ciro Leite

; Kmohan, Claudio

; Piras, Claudio

; Castro, Cristine Pilati Pileggi

; Lins, Cyntia

; Beraldo, Daniel

; Fontes, Daniel

; Boni, Daniela

; Castiglioni, Débora

; Paisani, Denise de Moraes

; Pedroso, Durval Ferreira Fonseca

; Mattos, Ederson Roberto

; Brito Sobrinho, Edgar de

; Troncoso, Edgar M. V.

; Rodrigues Filho, Edison Moraes

; Nogueira, Eduardo Enrico Ferrari

; Ferreira, Eduardo Leme

; Pacheco, Eduardo Souza

; Jodar, Euzebio

; Ferreira, Evandro L. A.

; Araujo, Fabiana Fernandes de

; Trevisol, Fabiana Schuelter

; Amorim, Fábio Ferreira

; Giannini, Fabio Poianas

; Santos, Fabrício Primitivo Matos

; Buarque, Fátima

; Lima, Felipe Gallego

; Costa, Fernando Antonio Alvares da

; Sad, Fernando Cesar dos Anjos

; Aranha, Fernando G.

; Ganem, Fernando

; Callil, Flavio

; Costa Filho, Francisco Flávio

; Dall´Arto, Frederico Toledo Campo

; Moreno, Geovani

; Friedman, Gilberto

; Moralez, Giulliana Martines

; Silva, Guilherme Abdalla da

; Costa, Guilherme

; Cavalcanti, Guilherme Silva

; Betônico, Gustavo Navarro

; Reis, Hélder

; Araujo, Helia Beatriz N.

; Hortiz Júnior, Helio Anjos

; Guimaraes, Helio Penna

; Urbano, Hugo

; Maia, Israel

; Santiago Filho, Ivan Lopes

; Farhat Júnior, Jamil

; Alvarez, Janu Rangel

; Passos, Joel Tavares

; Paranhos, Jorge Eduardo da Rocha

; Marques, José Aurelio

; Moreira Filho, José Gonçalves

; Andrade, Jose Neto

; Sobrinho, José Onofre de C

; Bezerra, Jose Terceiro de Paiva

; Alves, Juliana Apolônio

; Ferreira, Juliana

; Gomes, Jussara

; Sato, Karina Midori

; Gerent, Karine

; Teixeira, Kathia Margarida Costa

; Conde, Katia Aparecida Pessoa

; Martins, Laércia Ferreira

; Figueirêdo, Lanese

; Rezegue, Leila

; Tcherniacovsk, Leonardo

; Ferraz, Leone Oliveira

; Cavalcante, Liane

; Rabelo, Ligia

; Miilher, Lilian

; Garcia, Lisiane

; Tannous, Luana

; Hajjar, Ludhmila Abrahão

; Paciência, Luís Eduardo Miranda

; Cruz Neto, Luiz Monteiro da

; Bley, Macia Valeria

; Sousa, Marcelo Ferreira

; Puga, Marcelo Lourencini

; Romano, Marcelo Luz Pereira

; Nobrega, Marciano

; Arbex, Marcio

; Rodrigues, Márcio Leite

; Guerreiro, Márcio Osório

; Rocha, Marcone

; Alves, Maria Angela Pangoni

; Rosa, Maria Doroti

; Dias, Mariza D’Agostino

; Martins, Miquéias

; Oliveira, Mirella de

; Moretti, Miriane Melo Silveira

; Matsui, Mirna

; Messender, Octavio

; Santarém, Orlando Luís de Andrade

; Silveira, Patricio Júnior Henrique da

; Vassallo, Paula Frizera

; Antoniazzi, Paulo

; Gottardo, Paulo César

; Correia, Paulo

; Ferreira, Paulo

; Torres, Paulo

; Silva, Pedro Gabrile M. de Barros e

; Foernges, Rafael

; Gomes, Rafael

; Moraes, Rafael

; Nonato filho, Raimundo

; Borba, Renato Luis

; Gomes, Renato V

; Cordioli, Ricardo

; Lima, Ricardo

; López, Ricardo Pérez

; Gargioni, Ricardo Rath de Oliveira

; Rosenblat, Richard

; Souza, Roberta Machado de

; Almeida, Roberto

; Narciso, Roberto Camargo

; Marco, Roberto

; waltrick, Roberto

; Biondi, Rodrigo

; Figueiredo, Rodrigo

; Dutra, Rodrigo Santana

; Batista, Roseane

; Felipe, Rouge

; Franco, Rubens Sergio da Silva

; Houly, Sandra

; Faria, Sara Socorro

; Pinto, Sergio Felix

; Luzzi, Sergio

; Sant’ana, Sergio

; Fernandes, Sergio Sonego

; Yamada, Sérgio

; Zajac, Sérgio

; Vaz, Sidiner Mesquita

; Bezerra, Silvia Aparecida Bezerra

; Farhat, Tatiana Bueno Tardivo

; Santos, Thiago Martins

; Smith, Tiago

; Silva, Ulysses V. A.

; Damasceno, Valnei Bento

; Nobre, Vandack

; Dantas, Vicente Cés de Souza

; Irineu, Vivian Menezes

; Bogado, Viviane

; Nedel, Wagner

; Campos Filho, Walther

; Dantas, Weidson

; Viana, William

; Oliveira Filho, Wilson de

; Delgadinho, Wilson Martins

; Finfer, Simon

; Machado, Flavia Ribeiro

Revista Brasileira de Terapia Intensiva

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apr 2021, Volume 33 N. 2 Pages 206 - 218

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Objetivo: Descrever as práticas de ressuscitação volêmica em unidades de terapia intensiva brasileiras e compará-las com as de outros países participantes do estudo Fluid-TRIPS. Métodos: Este foi um estudo observacional transversal, prospectivo e internacional, de uma amostra de conveniência de unidades de terapia intensiva de 27 países (inclusive o Brasil), com utilização da base de dados Fluid-TRIPS compilada em 2014. Descrevemos os padrões de ressuscitação volêmica utilizados no Brasil em comparação com os de outros países e identificamos os fatores associados com a escolha dos fluidos. Resultados: No dia do estudo, foram incluídos 3.214 pacientes do Brasil e 3.493 pacientes de outros países, dos quais, respectivamente, 16,1% e 26,8% (p < 0,001) receberam fluidos. A principal indicação para ressuscitação volêmica foi comprometimento da perfusão e/ou baixo débito cardíaco (Brasil 71,7% versus outros países 56,4%; p < 0,001). No Brasil, a percentagem de pacientes que receberam soluções cristaloides foi mais elevada (97,7% versus 76,8%; p < 0,001), e solução de cloreto de sódio a 0,9% foi o cristaloide mais comumente utilizado (62,5% versus 27,1%; p < 0,001). A análise multivariada sugeriu que os níveis de albumina se associaram com o uso tanto de cristaloides quanto de coloides, enquanto o tipo de prescritor dos fluidos se associou apenas com o uso de cristaloides. Conclusão: Nossos resultados sugerem que cristaloides são usados mais frequentemente do que coloides para ressuscitação no Brasil, e essa discrepância, em termos de frequências, é mais elevada do que em outros países. A solução de cloreto de sódio 0,9% foi o cristaloide mais frequentemente prescrito. Os níveis de albumina sérica e o tipo de prescritor de fluidos foram os fatores associados com a escolha de cristaloides ou coloides para a prescrição de fluidos.

Abstract Objective: To describe fluid resuscitation practices in Brazilian intensive care units and to compare them with those of other countries participating in the Fluid-TRIPS. Methods: This was a prospective, international, cross-sectional, observational study in a convenience sample of intensive care units in 27 countries (including Brazil) using the Fluid-TRIPS database compiled in 2014. We described the patterns of fluid resuscitation use in Brazil compared with those in other countries and identified the factors associated with fluid choice. Results: On the study day, 3,214 patients in Brazil and 3,493 patients in other countries were included, of whom 16.1% and 26.8% (p < 0.001) received fluids, respectively. The main indication for fluid resuscitation was impaired perfusion and/or low cardiac output (Brazil: 71.7% versus other countries: 56.4%, p < 0.001). In Brazil, the percentage of patients receiving crystalloid solutions was higher (97.7% versus 76.8%, p < 0.001), and 0.9% sodium chloride was the most commonly used crystalloid (62.5% versus 27.1%, p < 0.001). The multivariable analysis suggested that the albumin levels were associated with the use of both crystalloids and colloids, whereas the type of fluid prescriber was associated with crystalloid use only. Conclusion: Our results suggest that crystalloids are more frequently used than colloids for fluid resuscitation in Brazil, and this discrepancy in frequencies is higher than that in other countries. Sodium chloride (0.9%) was the crystalloid most commonly prescribed. Serum albumin levels and the type of fluid prescriber were the factors associated with the choice of crystalloids or colloids for fluid resuscitation.

https://doi.org/10.5935/0103-507x.20210028 273 downloads

Determinant factors for immediate care seeking after traumatic dental injury among Brazilian children
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BRAGANÇA-SOUZA, Kátia Kely

; LISBOA, Jonathan Lopes de

; GUIMARÃES, Mariana Oliveira

; VIEIRA-ANDRADE, Raquel Gonçalves

; FREIRE-MAIA, Fernanda Bartolomeo

; MARTINS-JÚNIOR, Paulo Antônio

; AMARAL, Tânia Mara Pimenta

; Zarzar, Patrícia Maria

Brazilian Oral Research

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2021, Volume 35 elocation e112

Abstract: En | Text: En | PDF: En

Abstract The present study aimed to evaluate the frequency of immediate care seeking after traumatic dental injury (TDI) in primary dentition and its association with the children’s characteristics, socioeconomic status, and TDI characteristics. This was a cross-sectional study with dental records of children aged 9 months to 6 years who attended a reference center in TDI in primary dentition between 2007 and 2018. Immediate care seeking after TDI, child’s characteristics, sociodemographic conditions and TDI characteristics were collected. Descriptive statistics and Poisson regression analysis with robust variance were performed (p < 0.05; 95%CI). Among the 493 dental records, 61.1% (n = 301) were of males and 50.5% (n = 249) were from children aged 2 years or less. More than one third of the sample (36.9%; n = 182) sought immediate care after TDI. Among the types of TDI, the prevalence of soft tissue injuries was 59.0% (n = 291), while 51.7% (n = 255) were hard tissue injuries and 54.0% (n = 266) were supporting tissue injuries. Immediate care seeking after TDI was higher in children who needed suture (PR: 1.39; 95%CI: 1.01–1.92. p = 0.039), had luxation (lateral, intrusion, or extrusion) (PR: 2.36; 95%CI: 1.36–4.08. p = 0.002) or avulsion (PR: 2.18; 95%CI: 1.28–3.70. p = 0.004). The need for suture, luxation (lateral, intrusion and extrusion), and avulsion were determinant factors for the immediate care seeking after TDI, regardless of the child’s characteristics and socioeconomic status.

https://doi.org/10.1590/1807-3107bor-2021.vol35.0112 1 downloads

10.

Giardiasis in urban and rural Amazonas, Brazil is driven by zoonotic and cosmopolitan A and B assemblages
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dos Reis, Lisiane Lappe

; da Silva, Túllio Romão Ribeiro

; Braga, Francisco Carlos de Oliveira

; do Nascimento, Naara Macedo

; de Menezes, Katia Maria Lima

; Nava, Alessandra Ferreira Dales

; Lima, Natália Aparecida de Souza

; Vicente, Ana Carolina Paulo

Memórias do Instituto Oswaldo Cruz

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2021, Volume 116 elocation e210280

Abstract: En | Text: En | PDF: En

BACKGROUND Giardia duodenalis is a protozoan parasite that infects humans and other mammals and causes giardiasis worldwide. Giardia is genotyped into eight assemblages (A-H), with assemblages A and B considered zoonotic. OBJECTIVES The aim of this study was to determine the assemblages of G. duodenalis from individuals living in rural and urban areas of the Amazonas State. METHODS 103 human faecal specimens microscopically positive for the presence of Giardia obtained from four municipalities in Amazonas and four animal faecal specimens were genotyped based on the sequences of two genes, triosephosphate isomerase (TPI) and β-giardin (BG). FINDINGS In humans, assemblage A was the most represented with the identification of sub-assemblages AI, AII and AIII based on BG and sub-assemblages AI and AII based on TPI. Similarly, there is a diversity of sub-assemblage B considering BG (B and BIII) and TPI (B, BIII and BIV). In addition, we characterised homogeneous and heterogeneous genotypes comprising assemblages/sub-assemblages A and B in individuals from urban and rural areas. Here, for the first time, it was genotyped Giardia that infects animals from the Brazilian Amazon region. We identified sub-assemblage AI in one Ateles paniscus and two Felis catus and sub-assemblage BIV in one Lagothrix cana. MAIN CONCLUSIONS Therefore, humans and animals from the urban and rural Amazon share Giardia genotypes belonging to assemblages A and B, which are found in cosmopolitan regions around the world.

https://doi.org/10.1590/0074-02760210280

11.

Differences in children and adolescents with SARS-CoV-2 infection: a cohort study in a Brazilian tertiary referral hospital
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Marques, Heloisa Helena de Sousa

; Pereira, Maria Fernanda Badue

; Santos, Angélica Carreira dos

; Fink, Thais Toledo

; Paula, Camila Sanson Yoshino de

; Litvinov, Nadia

; Schvartsman, Claudio

; Delgado, Artur Figueiredo

; Gibelli, Maria Augusta Bento Cicaroni

; Carvalho, Werther Brunow de

; Odone Filho, Vicente

; Tannuri, Uenis

; Carneiro-Sampaio, Magda

; Grisi, Sandra

; Duarte, Alberto José da Silva

; Antonangelo, Leila

; Francisco, Rossana Pucineli Vieira

; Okay, Thelma Suely

; Batisttella, Linamara Rizzo

; Carvalho, Carlos Roberto Ribeiro de

; Brentani, Alexandra Valéria Maria

; Silva, Clovis Artur

; Eisencraft, Adriana Pasmanik

; Rossi Junior, Alfio

; Fante, Alice Lima

; Cora, Aline Pivetta

; Reis, Amelia Gorete A. de Costa

; Ferrer, Ana Paula Scoleze

; Andrade, Anarella Penha Meirelles de

; Watanabe, Andreia

; Gonçalves, Angelina Maria Freire

; Waetge, Aurora Rosaria Pagliara

; Silva, Camila Altenfelder

; Ceneviva, Carina

; Lazari, Carolina dos Santos

; Abellan, Deipara Monteiro

; Santos, Emilly Henrique dos

; Sabino, Ester Cerdeira

; Bianchini, Fabíola Roberta Marim

; Alcantara, Flávio Ferraz de Paes

; Ramos, Gabriel Frizzo

; Leal, Gabriela Nunes

; Rodriguez, Isadora Souza

; Pinho, João Renato Rebello

; Carneiro, Jorge David Avaizoglou

; Paz, Jose Albino

; Ferreira, Juliana Carvalho

; Ferranti, Juliana Ferreira

; Ferreira, Juliana de Oliveira Achili

; Framil, Juliana Valéria de Souza

; Silva, Katia Regina da

; Kanunfre, Kelly Aparecida

; Bastos, Karina Lucio de Medeiros

; Galleti, Karine Vusberg

; Cristofani, Lilian Maria

; Suzuki, Lisa

; Campos, Lucia Maria Arruda

; Perondi, Maria Beatriz de Moliterno

; Diniz, Maria de Fatima Rodrigues

; Fonseca, Maria Fernanda Mota

; Cordon, Mariana Nutti de Almeida

; Pissolato, Mariana

; Peres, Marina Silva

; Garanito, Marlene Pereira

; Imamura, Marta

; Dorna, Mayra de Barros

; Luglio, Michele

; Rocha, Mussya Cisotto

; Aikawa, Nadia Emi

; Degaspare, Natalia Viu

; Sakita, Neusa Keico

; Udsen, Nicole Lee

; Scudeller, Paula Gobi

; Gaiolla, Paula Vieira de Vincenzi

; Severini, Rafael da Silva Giannasi

; Rodrigues, Regina Maria

; Toma, Ricardo Katsuya

; Paula, Ricardo Iunis Citrangulo de

; Palmeira, Patricia

; Forsait, Silvana

; Farhat, Sylvia Costa Lima

; Sakano, Tânia Miyuki Shimoda

; Koch, Vera Hermina Kalika

; Cobello Junior, Vilson

Clinics

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2021, Volume 76 elocation e3488

Abstract: En | Text: En | PDF: En

OBJECTIVES: To compare demographic/clinical/laboratory/treatments and outcomes among children and adolescents with laboratory-confirmed coronavirus disease 2019 (COVID-19). METHODS: This was a cross-sectional study that included patients diagnosed with pediatric COVID-19 (aged <18 years) between April 11, 2020 and April 22, 2021. During this period, 102/5,951 (1.7%) of all admissions occurred in neonates, children, and adolescents. Furthermore, 3,962 severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) detection samples were processed in patients aged <18 years, and laboratory-confirmed COVID-19 occurred in 155 (4%) inpatients and outpatients. Six/155 pediatric patients were excluded from the study. Therefore, the final group included 149 children and adolescents (n=97 inpatients and 52 outpatients) with positive SARS-CoV-2 results. RESULTS: The frequencies of sore throat, anosmia, dysgeusia, headache, myalgia, nausea, lymphopenia, pre-existing chronic conditions, immunosuppressive conditions, and autoimmune diseases were significantly reduced in children and adolescents (p<0.05). Likewise, the frequencies of enoxaparin use (p=0.037), current immunosuppressant use (p=0.008), vasoactive agents (p=0.045), arterial hypotension (p<0.001), and shock (p=0.024) were significantly lower in children than in adolescents. Logistic regression analysis showed that adolescents with laboratory-confirmed COVID-19 had increased odds ratios (ORs) for sore throat (OR 13.054; 95% confidence interval [CI] 2.750-61.977; p=0.001), nausea (OR 8.875; 95% CI 1.660-47.446; p=0.011), and lymphopenia (OR 3.575; 95% CI 1.355-9.430; p=0.010), but also had less hospitalizations (OR 0.355; 95% CI 0.138-0.916; p=0.032). The additional logistic regression analysis on patients with preexisting chronic conditions (n=108) showed that death as an outcome was significantly associated with pediatric severe acute respiratory syndrome (SARS) (OR 22.300; 95% CI 2.341-212.421; p=0.007) and multisystem inflammatory syndrome in children (MIS-C) (OR 11.261; 95% CI 1.189-106. 581; p=0.035). CONCLUSIONS: Half of the laboratory-confirmed COVID-19 cases occurred in adolescents. Individuals belonging to this age group had an acute systemic involvement of SARS-CoV-2 infection. Pediatric SARS and MIS-C were the most important factors associated with the mortality rate in pediatric chronic conditions with COVID-19.

https://doi.org/10.6061/clinics/2021/e3488

12.

Implantable cardioverter-defibrillator prevents sudden death in patients with Chagas cardiomyopathy in the Brazilian Amazon
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Couceiro, Katia do Nascimento

; Ortiz, Jessica Vanina

; Silva, Mônica Regina Hosannah da Silva e

; Sousa, Débora Raysa Teixeira de

; Souza, Kenny Rodrigues de

; Alencar, Gabriela Maciel

; Magalhães, Laylah Kelre Costa

; Guerra, Maria das Graças Vale Barbosa

; Ferreira, João Marcos Bemfica Barbosa

; Guerra, Jorge Augusto de Oliveira

Revista da Sociedade Brasileira de Medicina Tropical

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2021, Volume 54 elocation e0480-2020

Abstract: En | Text: En | PDF: En

Abstract Chagas disease (CD), with approximately 10,000 deaths annually, has become a worldwide health problem. Approximately 35% of cases may show cardiac manifestations such as arrhythmias and/or conduction disorders, heart failure, thromboembolic accidents, and sudden death. The Amazon region has long been considered a non-endemic area for CD; however, in the last decades, with an increase in the number of acute and chronic cases, disease evolution has received greater attention. Here, we report the successful implementation of a cardioverter-defibrillator for the prevention of sudden death in a patient with autochthonous Chagas cardiomyopathy in the Brazilian Amazon.

https://doi.org/10.1590/0037-8682-0480-2020 271 downloads

13.

Oficinas em saúde do trabalhador: ação educativa e produção dialógica de conhecimento sobre trabalho docente em universidade pública
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Souza, Kátia Reis de

; Rodrigues, Andréa Maria dos Santos

; Santos, Maria Blandina Marques dos

; Felix, Eliana Guimarães

; Barbosa, Regina Helena Simões

; Fernandez, Verônica Silva

; Barros, Walcyr de Oliveira

Revista Brasileira de Saúde Ocupacional

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2020, Volume 45 elocation e4

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Objetivo: analisar a abordagem metodológica “Oficinas em saúde do trabalhador” e seus resultados acerca das relações entre trabalho docente e saúde em universidade pública. Métodos: pesquisa social de caráter qualitativo e de natureza pedagógica e participativa. “Oficinas em saúde do trabalhador” são espaços onde trabalhadores e pesquisadores discutem temas de trabalho relacionados à saúde, pautados em investigação participativa e pedagogia freireana e em fundamentos do campo da Saúde do Trabalhador, principalmente o modelo operário de conhecimento e a teoria de Gramsci. Foram realizadas quatro reuniões com oito docentes pertencentes ao mesmo instituto de uma universidade federal localizada no estado do Rio de Janeiro. Resultados: no plano epistemológico, analisaram-se importantes temas acerca do trabalho e da saúde docentes, sendo eles: precarização da infraestrutura universitária e as condições de trabalho docente; relações coletivas e conflitos; sentidos e ambivalência do trabalho docente; queixas de saúde e intensificação do trabalho. Conclusão: este estudo possibilitou o desenvolvimento de abordagem metodológica de caráter dialógico e participativo. Embora o estudo esteja circunscrito a um pequeno grupo, o método propiciou identificar e analisar importantes aspectos do trabalho e da saúde docente que constatam transformações no trabalho em universidade, apontando para a necessidade de estudos de maior alcance.

Abstract Objective: to analyze the methodological approach “Workshops on workers’ health” and its results regarding the relationship between health and teaching in public universities. Methods: social study of qualitative, pedagogical and participatory approach. “Workshops on workers’ health” are spaces where workers and researchers discuss the work and health relation in accordance with participative research, Freire’s pedagogy and Workers’ Health concepts, especially the Workers’ Model of Knowledge and Gramsci’s theory. Four meetings were held with eight professors of the same institute in a federal university situated in the state of Rio de Janeiro, Brazil. Results: epistemologically, important subjects concerning the work and health of teachers were analyzed, namely: university infrastructure precarization and teaching work conditions; collective relations and conflicts; teacher work meanings and ambivalence; health complaints and work intensification. Conclusion: this study enabled the development of a dialogical and participatory methodological approach. Although this study was limited to a small group, the method enabled the identification and analysis of important aspects of work and health of teaching at the university, showing the transformations in university work and indicating the need for studies of larger scope.

https://doi.org/10.1590/2317-6369000015818 1576 downloads

14.

Evaluation of anemia after long-term treatment with imatinib in chronic myeloid leukemia patients in chronic phase
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Moura, Muriel Silva

; Benevides, Thais Celi Lopes

; Delamain, Marcia Torresan

; Duarte, Gislaine Oliveira

; Percout, Priscila Oliveira

; Dias, Maria Almeida

; Zulli, Roberto

; Souza, Carmino Antonio de

; Lorand-Metze, Irene

; Pagnano, Katia Borgia Barbosa

Hematology, Transfusion and Cell Therapy

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dec 2019, Volume 41 N. 4 Pages 329 - 334

Abstract: En | Text: En | PDF: En

ABSTRACT Introduction: The incidence of grade 3-4 anemia was reported to be 3% with imatinib therapy for newly diagnosed chronic myeloid leukemia (CML) in the chronic phase (CP). However, there are few data regarding the causes and the development of anemia after long-term treatment. This study aimed to evaluate the incidence of anemia after at least two years of imatinib treatment of CML patients in the CP and to identify other contributing causes of anemia in this population. Patients and methods: We performed a retrospective analysis of 97 CML patients in the CP treated with imatinib for at least two years. We analyzed the hemoglobin (Hb) levels of CML patients at diagnosis, upon initiation of treatment with imatinib and after two years of imatinib treatment, and investigated other causes of anemia in this population. Results: Most of the patients presented Hb levels below the normal range (80.4%) after the second year of treatment, 17.9% grade 2 and 1.3% grade 3. In 13 cases (16.7%), anemia was attributed to resistance and in 13 cases (16.7%) the following causes were identified: iron deficiency (n = 5), hypothyroidism (n = 2), vitamin B12 deficiency (n = 3), acquired immune deficiency syndrome (AIDS) (n = 1), pulmonary tuberculosis (n = 1) and renal toxicity (n = 1). In 52 patients (66.6%), there were no other factors contributing to anemia, except imatinib treatment. Conclusion: Regular follow-up is required to identify the causes of anemia not related to CML or imatinib toxicity. The importance of investigating secondary causes of anemia should be emphasized, especially in patients with good adherence to treatment and satisfactory therapeutic response.

https://doi.org/10.1016/j.htct.2019.03.006 458 downloads

15.

The QualiRede intervention: improving the performance of care continuum in HIV, congenital syphilis, and hepatitis C in health regions
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Nemes, Maria Ines Battistella

; Castanheira, Elen Rose Lodeiro

; Alves, Ana Maroso

; Adania, Carolina Simone Souza

; Loch, Ana Paula

; Monroe, Aline Aparecida

; Souza, Rosa Alencar

; Gianna, Maria Clara

; Caminada, Sirlene

; Farias, Norma Suely de Oliveira

; Sousa, Paula de Oliveira e

; Domingues, Carmen Silva Bruniera

; Silva, Mariliza Henrique da

; Cervantes, Vilma

; Yamashiro, Juliana

; Caraciolo, Joselita Maria de Magalhães

; Silva, Fabiano Lima da

; Nemes Filho, Alexandre

; Jesus, Gabriel Lima de

; Helena, Ernani Tiaraju de Santa

; Albiero, José Francisco Gontan

; Lima, Marcela Soares Silveira

; Bellenzani, Renata

; Kehrig, Ruth Terezinha

; Vale, Felipe Campos do

; Nunes, Luceime Olivia

; Mendonça, Carolina Siqueira

; Zarili, Thais Fernanda Tortorelli

; Vilela, Mara Cristina

; Dantas, Jean Carlos de Oliveira

; Paula, Ivone de

; Tayra, Ângela

; Coelho, Débora Moraes

; Santos, Glauber Palha dos

; Quevedo, Dulce Castro

; Silva, Marcia Aparecida da

; Silva, Iraci Batista da

; Nasser, Mariana Arantes

; Andrade, Marta Campagnoni

; Santos, Maria Altenfelder

; Mercuri, Juliana

; Trindade, Katia Valeska

; Neves, Maria Aparecida Teixeira das

; Toledo, Renata Villanueva Alves de

; Almeida, Maria Cecília Rossi de

; Lima, Iraty Nunes

Revista Brasileira de Epidemiologia

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2019, Volume 22 Suppl. 1 elocation e190010

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Introdução: Modelos de cuidado contínuo baseiam recentes estratégias em HIV, infecções sexualmente transmissíveis e hepatite C (HCV). Métodos: Desenvolveram-se modelos de contínuo do cuidado em HIV, HCV e sífilis congênita incluindo todas as etapas da atenção, desde a promoção e a prevenção até o controle clínico/cura. O modelo baseou a intervenção QualiRede, desenvolvida em parceria entre universidade e Sistema Único de Saúde (SUS), direcionada a gestores e demais profissionais de 6 regiões de saúde prioritárias em São Paulo e Santa Catarina. Selecionaram-se indicadores para cada etapa do contínuo do cuidado, provenientes dos sistemas de informação do SUS e dos questionários de avaliação de processo Qualiaids e QualiAB. Os indicadores formaram a base técnica de duas oficinas com profissionais e gestores de cada região: a primeira para identificar problemas e formar um Grupo Técnico Regional; e a segunda para construir planos de ação e metas a fim de melhorar o desempenho regional. Resultados: Os indicadores estão disponíveis no website www.qualirede.org. As oficinas ocorreram em quatro regiões de São Paulo (Alto Tietê, Baixada Santista, Grande ABC e Registro) e uma região de Santa Catarina (Foz do Rio Itajaí), resultando em planos regionais em São Paulo, mas não em Santa Catarina. Observou-se domínio limitado dos novos protocolos para HIV e HCV e uso incipiente de indicadores na rotina dos serviços. Conclusão: Melhorar o desempenho do contínuo do cuidado exige apropriação dos indicadores de desempenho e coordenação integrada dos fluxos de atenção em todos os níveis de gestão.

ABSTRACT Introduction: Care continuum models have supported recent strategies against sexually transmitted diseases, such as HIV and Hepatitis C (HCV). Methods: HIV, HCV, and congenital syphilis care continuum models were developed, including all stages of care, from promotion/prevention to clinical control/cure. The models supported the intervention QualiRede, developed by a University-Brazilian National Health System (SUS) partnership focused on managers and other professionals from six priority health regions in São Paulo and Santa Catarina. Indicators were selected for each stage of the care continuum from the SUS information systems and from the Qualiaids and QualiAB facility’s process evaluation questionnaires. The indicators acted as the technical basis of two workshops with professionals and managers in each region: the first one to identify problems and to create a Regional Technical Group; and the second one to design action plans for improving regional performance. Results: The indicators are available at www.qualirede.org. The workshops took place in the regions of Alto Tietê, Baixada Santista, Grande ABC, and Registro (São Paulo) and of Foz do Rio Itajaí (Santa Catarina), which resulted in regional action plans in São Paulo, but not in Santa Catarina. A lack of awareness was observed regarding the new HIV and HCV protocols, as well as an incipient use of indicators in routine practices. Conclusion: Improving the performance of the care continuum requires appropriation of performance indicators and coordination of care flows at local, regional, and state levels of management.

https://doi.org/10.1590/1980-549720190010.supl.1 2475 downloads

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Glossary and search help

You can enrich your search in a very simple way. Use the search indexes combined with the connectors (AND or OR) and specify more your search.

For example, if you want to search for articles about
cases of dengue in Brasil in 2015, use:
ti:dengue and publication_year:2015 and aff_country:Brasil

See below the complete list of search indexes that can be used:

Index code	Element
ti	article title
au	author
kw	article keywords
subject	subject (title words, abstract and keywords)
ab	abstract
ta	journal short title (e.g. Cad. Saúde Pública)
journal_title	journal full title (e.g. Cadernos de Saúde Pública)
la	publication language code (e.g. pt - Portuguese, es - Spanish)
type	document type
pid	publication identifier
publication_year	publication year of publication
sponsor	sponsor
aff_country	country code of the author's affiliation
aff_institution	author affiliation institution
volume	article volume
issue	article issue
elocation	elocation
doi	DOI number
issn	journal ISSN
in	SciELO colection code (e.g. scl - Brasil, col - Colômbia)
use_license	article usage license code

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