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1.
Unraveling trait relationships for the selection of drought-tolerant wheat genotypes droughttolerant drought tolerant
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Ribeiro, João Paulo Oliveira
; Silva, Caique Machado e
; Sousa, João Marcos Amario de
; Freitas, Davi Soares de
; Mezzomo, Henrique Caletti
; Vasconcelos, Aline de Almeida
; Nardino, Maicon
.
RESUMO: O estudo das relações genotípicas entre índices de tolerância à seca e caracteres agronômicos de interesse no melhoramento de trigo é útil para traçar estratégias de seleção. Objetivou-se com este trabalho investigar as relações de causa e efeito entre características agronômicas e índices de tolerância à seca via análise de correlações canônicas. Dois ensaios (controle e estresse) foram conduzidos no inverno de 2020 em Viçosa, MG, Brasil. Foram avaliados os caracteres (dias para o espigamento, altura da planta, massa e número de grãos por espiga, massa de cem grãos e rendimento de grãos). Os dados de produtividade dos ensaios de controle e estresse foram utilizados para construir cinco índices de tolerância à seca. Os dados foram submetidos à análise de modelos mistos para estimação dos parâmetros genéticos e predição dos valores genotípicos (REML/BLUP), em seguida, os valores genotípicos foram utilizados para calcular os coeficientes de correlação entre os caracteres. Dois grupos de caracteres foram estabelecidos para o estudo das correlações canônicas, sendo o primeiro grupo constituído pelas variáveis agronômicas e o segundo pelos índices de tolerância à seca. Houve efeito significativo de genótipo para todas as características avaliadas. Os pares canônicos foram significativos, o que indicou a existência de dependência entre os grupos. O caráter dias para o espigamento pode ser utilizado na seleção indireta de genótipos de trigo para tolerância à seca. RESUMO Objetivouse Objetivou se canônicas 202 Viçosa MG Brasil planta espiga grãos. . grãos) REML/BLUP, REMLBLUP REML/BLUP , REML BLUP (REML/BLUP) seguida avaliadas significativos 20 (REML/BLUP 2
ABSTRACT: The study of genotypic relationships between drought tolerance indices and agronomic traits of interest in wheat breeding is useful for designing selection strategies. The objective of this research was to investigate the cause-and-effect relationships between agronomic traits and drought tolerance indices through the analysis of canonical correlations. Two trials (control and stress) were conducted in winter 2020 in Viçosa, MG, Brazil. The traits evaluated were: (days for heading, plant height, mass and number of grains per spike, mass of one hundred grains, and grain yield). Grain yield data from the control and stress conditions were used to construct five drought tolerance indices. The data were subjected to mixed model analysis for estimation of genetic parameters and prediction of genotypic values (REML/BLUP), and then the genotypic values were used to calculate the correlation coefficients between the traits. Two groups of traits were established for the study of canonical correlations, the first group consisting of agronomic traits and the second by drought tolerance indices. There was a significant genotype effect for all evaluated traits. The canonical pairs were significant, which indicated the existence of dependence between the groups. Days to heading trait can be used in the indirect selection of wheat genotypes for drought tolerance. ABSTRACT strategies causeandeffect cause correlations 202 Viçosa MG Brazil days height spike yield. . yield) REML/BLUP, REMLBLUP REML/BLUP , REML BLUP (REML/BLUP) 20 (REML/BLUP 2
2.
Suporte imediato de vida na pessoa em situação crítica: Contributos da intervenção do enfermeiro
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Miranda, José Paulo Passos de
; Silva, Márcio Daniel Dias de Almeida e
; Sousa, Clementina
; Magalhães, José
; Graça, Luís Carlos Carvalho
.
Resumo Enquadramento: As ambulâncias de suporte imediato de vida (SIV) possibilitam ao enfermeiro capacidade de intervenção em contexto pré-hospitalar, suportada pelo seu conhecimento técnico-científico, protocolos complexos de atuação e regulação médica por telemedicina. Objetivo: Analisar os contributos da intervenção dos enfermeiros SIV, na evolução do estado clínico da pessoa em situação crítica (PSC). Metodologia: Estudo quantitativo, descritivo-correlacional, retrospetivo, realizado em meios SIV, na região norte de Portugal. Analisados 574 registos clínicos eletrónicos, entre 01 de novembro e 31 de dezembro de 2019, que correspondem ao mesmo número de pessoas avaliadas. Utilizada a escala National Early Warning Score (NEWS) para avaliar a evolução clínica da PSC. Resultados: Observou-se uma evolução positiva do score NEWS da PSC, após a intervenção do enfermeiro SIV (M = 4,43 ± 3,901 vs 3,34 ± 3,329; sig < 0,001). Em sentido inverso, o risco clínico diminuiu significativamente após a intervenção do enfermeiro. Conclusão: Demonstrou-se a relevância da intervenção do enfermeiro SIV no contexto pré-hospitalar, enquanto garantia de segurança, qualidade e melhoria contínua dos cuidados à PSC.
Abstract Background: Immediate life support (ILS) ambulances allow nurses to intervene in pre-hospital settings, supported by their technical-scientific knowledge and complex protocols of action and regulation through telemedicine. Objective: To analyze the contributions of nursing interventions in the evolution of the clinical state of critical patients. Methodology: Quantitative, descriptive-correlational, retrospective, and observational study conducted in ILS settings in northern Portugal. A total of 574 electronic clinical records were analyzed between 1 November and 31 December 2019, corresponding to the same number of people evaluated. The National Early Warning Score (NEWS) was used to assess the clinical evolution of critical patients. Results: There was a positive evolution of the NEWS score of critical patients after the intervention of ILS nurses (M = 4.43 ± 3.901 vs. 3.34 ± 3.329; sig < 0.001). Similarly, the clinical risk of critical patients decreased after the nurse’s intervention. Conclusion: This study demonstrated the importance of nurses in prehospital care, as a guarantee of safety, quality, and continuous improvement of care for critical patients.
Resumen Marco contextual: Las ambulancias de soporte vital inmediato (SVI) permiten al personal de enfermería intervenir en un contexto prehospitalario, con el apoyo de sus conocimientos técnico-científicos y de complejos protocolos de actuación y regulación médica a través de la telemedicina. Objetivo: Analizar las aportaciones de la intervención del personal de enfermería del SVI en la evolución del estado clínico de la persona en situación crítica (PSC). Metodología: Estudio cuantitativo, descriptivo-correlacional, retrospectivo, realizado en centros de SVI del norte de Portugal. Se analizaron 574 historias clínicas electrónicas entre el 1 de noviembre y el 31 de diciembre de 2019, correspondientes al mismo número de personas evaluadas. Se utilizó la escala National Early Warning Score (NEWS) para evaluar la evolución clínica de la PSC. Resultados: Se observó una evolución positiva en el score NEWS de la PSC, tras la intervención del personal de enfermería del SVI (M = 4,43 ± 3,901 vs 3,34 ± 3,329; sig < 0,001). Por el contrario, el riesgo clínico disminuyó significativamente tras la intervención del personal de enfermería. Conclusión: Se demostró la relevancia de la intervención del personal de enfermería del SVI en el contexto prehospitalario, como garantía de seguridad, calidad y mejora continua en la atención a la PSC.
3.
Persistent and Intrusive Negative Thoughts Scale (PINTS): Adaptação e evidências psicométricas em universitários brasileiros
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Bezerra de Medeiros, Paloma Cavalcante
; Raiane de Araújo, Gleyde
; de Carvalho Sousa, Maria Carolina
; Nascimento da Silva, Paulo Gregório
; Lopes da Cunha, Laís Renata
; Silva e Araújo, Ramnsés
; Diógenes de Medeiros, Emerson
.
Abstract Introduction: Repetitive Negative Thinking (RNT) can be characterized as intrusive thoughts about worries (current, past, or future), negative experiences, and self-criticism, manifesting excessively and persistently. In a transdiagnostic process, it is identified that the RNT contributes to the onset and maintenance of multiple disorders. The present study aimed to adapt the Persistent and Intrusive Negative Thoughts Scale (PINTS) for the Brazilian context, investigating the psychometric qualities of the instrument. Method: Two studies were carried out with participants from different Brazilian states. In Study 1 (n = 258), the adaptation of PINTS and an exploratory factor analysis was performed. In Study 2 (n = 270), a confirmatory factor analysis was conducted, and evidence of convergent validity was gathered. Results: Firstly, in Study 1, a unifactorial structure of the measure was indicated. Through Study 2, the unifactorial structure was corroborated, demonstrating adequate internal consistency (precision), demonstrating that PINTS positively correlated with negative affectivity (stress, anxiety, and depression) and cognitive test anxiety. Conclusion: It is concluded that PINTS exhibited satisfactory metric qualities, being a brief and easy-to-administer measure, potentially serving as a useful tool for researchers investigating maladaptive repetitive negative thinking and its correlates.
Resumo Introdução: o pensamento repetitivo negativo (PRN) pode ser caracterizado como pensamentos intrusivos sobre preocupações (atuais, passadas ou futuras), experiências negativas e autocríticas, manifestando-se de forma excessiva e persistente. Em um processo transdiagnóstico, identifica-se que o PRN contribui para o aparecimento e manutenção de transtornos múltiplos. O presente estudo objetivou adaptar a Persistent and Intrusive Negative Thoughts Scale (PINTS) para o contexto brasileiro, averiguando as qualidades psicométricas do instrumento. Método: procedeu-se a dois estudos com participantes de diferentes estados brasileiros. No estudo 1 (n = 258), foi realizada a adaptação da PINTS e uma análise fatorial exploratória. No estudo 2, (n = 270), foi realizada uma análise fatorial confirmatória além de reunidas evidências de validade convergente. Resultados: primeiramente, o estudo 1 apontou uma estrutura unifatorial da medida. A partir do estudo 2, foram corroboradas a estrutura unifatorial e a adequada consistência interna (precisão), o que demonstrou que a PINTS se relacionou positivamente com a afetividade negativa (estresse, ansiedade e depressão) e com a ansiedade cognitiva de provas. Conclusão: conclui-se que a PINTS apresentou qualidades métricas satisfatórias, sendo uma medida curta e de fácil aplicação, podendo ser uma ferramenta útil para pesquisadores que buscam investigar o PRN desadaptativo e os seus correlatos.
4.
Evaluation of the efficacy and safety of cannabidiol-rich cannabis extract in children with autism spectrum disorder: randomized, double-blind, and placebo-controlled clinical trial cannabidiolrich cannabidiol rich disorder randomized doubleblind, doubleblind double blind, blind double-blind placebocontrolled placebo controlled
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Silva Junior, Estácio Amaro da
; Medeiros, Wandersonia Moreira Brito
; Santos, João Paulo Mendes dos
; Sousa, João Marçal Medeiros de
; Costa, Filipe Barbosa da
; Pontes, Katiúscia Moreira
; Borges, Thaís Cavalcanti
; Neto Segundo, Carlos Espínola
; Andrade e Silva, Ana Hermínia
; Nunes, Eliane Lima Guerra
; Alves, Nelson Torro
; Rosa, Marine Diniz da
; Albuquerque, Katy Lísias Gondim Dias de
.
Abstract Objective Autism spectrum disorder (ASD) is characterized by persistent deficits in social communication and social interaction and by restricted and repetitive patterns of behavior. Some studies have shown that substances derived from Cannabis sativa improve the quality of life of children with ASD without causing serious adverse effects, thus providing an alternative therapeutic option. The objective of this study was to evaluate the efficacy and safety of a cannabis extract rich in cannabidiol (CBD) in children with ASD. Methods In this randomized, double-blind, placebo-controlled clinical trial, 60 children, aged from 5 to 11 years, were selected and divided into two groups: the treatment group, which received the CBD-rich cannabis extract, and the control group, which received the placebo. They both used their respective products for a period of 12 weeks. Statistical analysis was done by two-factor mixed analysis of variance (two-way ANOVA). Results Significant results were found for social interaction (F1,116 = 14.13, p = 0.0002), anxiety (F1,116 = 5.99, p = 0.016), psychomotor agitation (F1,116 = 9.22, p = 0.003), number of meals a day (F1,116 = 4.11, p = 0.04), and concentration (F1,48 = 6.75, p = 0.01), the last of which was only significant in mild ASD cases. Regarding safety, it was found that only three children in the treatment group (9.7%) had adverse effects, namely dizziness, insomnia, colic, and weight gain. Conclusion CBD-rich cannabis extract was found to improve one of the diagnostic criteria for ASD (social interaction), as well as features that often co-exist with ASD, and to have few serious adverse effects. (ASD behavior effects option CBD (CBD randomized doubleblind, doubleblind double blind, blind double-blind placebocontrolled placebo controlled trial 6 1 years groups CBDrich weeks twofactor factor twoway way ANOVA. ANOVA . ANOVA) F1,116 F1116 F F1 116 (F1,11 1413 14 13 14.13 0.0002, 00002 0.0002 , 0 0002 0.0002) 599 99 5.99 0.016, 0016 0.016 016 0.016) 922 9 22 9.22 0.003, 0003 0.003 003 0.003) 411 4 4.11 0.04, 004 0.04 04 0.04) F1,48 F148 48 (F1,4 675 75 6.75 0.01, 001 0.01 01 0.01) cases 9.7% 97 7 (9.7% dizziness insomnia colic gain interaction, interaction) coexist co exist F1,11 F111 (F1,1 141 14.1 0000 0.000 000 59 5.9 92 2 9.2 0.00 00 41 4.1 0.0 F1,4 F14 (F1, 67 6.7 9.7 (9.7 F1,1 F11 14. 5. 9. 4. 0. F1, (F1 6. (9. (F (9 (
5.
Therapeutic Adherence According to the Morisky Scale in Patients with Hypertension
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Lanza, Vinícius Encenha
; Silva, Gabriel Oliveira
; Quiroga, Celi Cristina Calamita
; Cavalcante, Margaret Assad
; Barroso, Weimar Kunz Sebba
; Brandão, Andréa Araujo
; Barbosa, Eduardo Costa Duarte
; Malachias, Marcus Vinicius Bolivar
; Gomes, Marco Mota
; Amodeo, Celso
; Povoa, Rui Manoel dos Santos
; Précoma, Dalton Bertolim
; Sousa, Antônio Carlos Sobral
; Dantas, João Miguel Malta
; Cesarino, Evandro José
; Barros e Silva, Pedro G. M. de
; Veiga Jardim, Paulo Cesar B.
; Lopes, Renato D.
.
International Journal of Cardiovascular Sciences
- Journal Metrics
Abstract Background In view of the high prevalence of hypertension and the importance of adequate drug therapy in the prevention of complications, it is necessary to know the adherence to drug treatment in this population. Objective To verify adherence to antihypertensive drug treatment in Brazilian patients with hypertension using the Morisky-Green Test (MGT), relating it with demographic data. Methods Prospective, observational, multicenter, national registry study, with 2,578 hypertensive patients participating in study I, the Brazilian Cardiovascular Registry of Arterial Hypertension (I-RBH), recruited in the five regions of Brazil. The analyses carried out on the data were descriptive statistics, qui-square tests, ANOVA, and logistic regression, adopting 5% as the significance level for the tests. Results The research shows that 56.13% of patients in the sample were female; 56.71% were elderly (≥ 65 years); 55.86% were White; 52.37% were from the Southeast Region; and 59.74% were non-adherent. Logistic regression showed an independent relationship between patients’ age, ethnicity, and region with medication adherence. Conclusion Adherence to treatment is the key to reducing high rates of cardiovascular complications. The study brings a successful outcome in the relationship between the factors ethnicity, age, and region of patients with hypertension and medication adherence. To this end, it is necessary to understand these factors, considering systematic evaluation in the care of patients with hypertension and other chronic non-communicable diseases. This study is a significant contribution to multidisciplinary teams, as it highlights which risk factors interfere with medication adherence, incorporating better strategies in health education. complications population MoriskyGreen Morisky Green MGT, MGT , (MGT) Prospective observational multicenter 2578 2 578 2,57 I IRBH, IRBH RBH (I-RBH) Brazil statistics quisquare qui square tests ANOVA 5 5613 56 13 56.13 female 5671 71 56.71 ≥ ( 6 years years) 5586 55 86 55.86 White 5237 52 37 52.37 Region 5974 59 74 59.74 nonadherent. nonadherent non adherent. adherent non-adherent age ethnicity end noncommunicable communicable diseases teams education (MGT 257 57 2,5 (I-RBH 561 1 56.1 567 7 56.7 558 8 55.8 523 3 52.3 597 59.7 25 2, 56. 55. 52. 59.
6.
Characterisation of an area of coexistent visceral and cutaneous leishmaniasis transmission in the State of Piauí, Brazil Piauí
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Vasconcelos, Silvia Alcântara
; de Sousa, Raimundo Leoberto Torres
; Costa Junior, Enéas
; Diniz e Souza, João Paulo
; Cavalcante, Diane
; da Silva, Antônio Carlos Lima
; de Mendonça, Ivete Lopes
; Mallet, Jacenir
; Teixeira, Clarissa Romero
; Werneck, Guilherme Loureiro
; Araújo-Pereira, Thais
; Pita-Pereira, Daniela
; Britto, Constança
; Vilela, Maurício Luiz
; Gomes, Regis
.
BACKGROUND In Brazil, transmission of visceral and cutaneous leishmaniasis has expanded geographically over the last decades, with both clinical forms occurring simultaneously in the same area. OBJECTIVES This study characterised the clinical, spatial, and temporal distribution, and performed entomological surveillance and natural infection analysis of a leishmaniasis-endemic area. METHODS In order to characterise the risk of leishmaniasis transmission in Altos, Piauí, we described the clinical and socio-demographic variables and the spatial and temporal distribution of cases of American visceral leishmaniasis (AVL) and American cutaneous leishmaniasis (ACL) cases and identified potential phlebotomine vectors. FINDINGS The urban area concentrated almost 54% of ACL and 86.8% of AVL cases. The temporal and spatial distribution of AVL and ACL cases in Altos show a reduction in the number of risk areas, but the presence of permanent disease transmission foci is observed especially in the urban area. 3,808 phlebotomine specimens were captured, with Lutzomyia longipalpis as the most frequent species (98.45%). Of the 35 females assessed for natural infection, one specimen of Lu. longipalpis tested positive for the presence of Leishmania infantum and Leishmania braziliensis DNA. MAIN CONCLUSION Our results indicate the presence of risk areas for ACL and AVL in the municipality of Altos and highlight the importance of entomological surveillance to further understand a possible role of Lu. longipalpis in ACL transmission. Brazil decades leishmaniasisendemic endemic Piauí sociodemographic socio demographic (AVL (ACL vectors 54 868 86 8 86.8 3808 3 808 3,80 captured 98.45%. 9845 98.45% . 98 45 (98.45%) Lu DNA 5 86. 380 80 3,8 984 98.45 9 4 (98.45% 38 3, 98.4 (98.45 98. (98.4 (98. (98 (9 (
7.
Lung cancer screening in Brazil: recommendations from the Brazilian Society of Thoracic Surgery, Brazilian Thoracic Association, and Brazilian College of Radiology and Diagnostic Imaging Brazil Surgery Association
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Pereira, Luiz Fernando Ferreira
; Santos, Ricardo Sales dos
; Bonomi, Daniel Oliveira
; Franceschini, Juliana
; Santoro, Ilka Lopes
; Miotto, André
; Sousa, Thiago Lins Fagundes de
; Chate, Rodrigo Caruso
; Hochhegger, Bruno
; Gomes Neto, Artur
; Schneider, Airton
; Araújo Neto, César Augusto de
; Escuissato, Dante Luiz
; Prado, Gustavo Faibischew
; Costa-Silva, Luciana
; Zamboni, Mauro Musa
; Ghefter, Mario Claudio
; Corrêa, Paulo César Rodrigues Pinto
; Torres, Pedro Paulo Teixeira e Silva
; Mussi, Ricardo Kalaf
; Muglia, Valdair Francisco
; Godoy, Irma de
; Bernardo, Wanderley Marques
.
RESUMO O câncer de pulmão (CP) é uma das neoplasias mais comuns e letais no Brasil, e apenas 15% dos pacientes são diagnosticados nos estágios iniciais. O tabagismo persiste como o responsável por mais de 85% de todos os casos. O rastreamento do CP (RCP) por meio da TC de baixa dosagem de radiação (TCBD) reduz a mortalidade do CP em 20%, e, quando combinado com a cessação do tabagismo, essa redução chega a 38%. Na última década, diversos países adotaram o RCP como recomendação de saúde populacional. No Brasil, embora ainda incipiente, a discussão sobre o tema é cada vez mais ampla e necessária. Com o intuito de aumentar o conhecimento e estimular o debate sobre o RCP, a Sociedade Brasileira de Cirurgia Torácica, a Sociedade Brasileira de Pneumologia e Tisiologia e o Colégio Brasileiro de Radiologia e Diagnóstico por Imagem constituíram um painel de especialistas para elaborar as recomendações para o RCP. As recomendações aqui apresentadas foram baseadas em revisão narrativa da literatura, com ênfase em grandes estudos populacionais, em revisões sistemáticas e em recomendações de diretrizes internacionais, sendo construídas após ampla discussão pelo grupo de especialistas. Os temas revisados foram os seguintes: porque rastrear, considerações gerais sobre tabagismo, epidemiologia do CP, critérios de elegibilidade, achados incidentais, lesões granulomatosas, modelos probabilísticos, requisitos mínimos da TCBD, aquisições volumétricas, riscos do rastreamento, estrutura mínima e papel da equipe multidisciplinar, conduta segundo o Lung CT Screening Reporting and Data System (Lung-RADS), custos vs. benefícios e perspectivas do rastreamento. (CP Brasil 15 iniciais 85 casos (RCP TCBD (TCBD 20 20% 38 38% década populacional incipiente necessária Torácica literatura populacionais internacionais seguintes rastrear elegibilidade incidentais granulomatosas probabilísticos volumétricas multidisciplinar LungRADS, LungRADS RADS , (Lung-RADS) vs 1 8 2 3 (Lung-RADS
ABSTRACT Although lung cancer (LC) is one of the most common and lethal tumors, only 15% of patients are diagnosed at an early stage. Smoking is still responsible for more than 85% of cases. Lung cancer screening (LCS) with low-dose CT (LDCT) reduces LC-related mortality by 20%, and that reduction reaches 38% when LCS by LDCT is combined with smoking cessation. In the last decade, a number of countries have adopted population-based LCS as a public health recommendation. Albeit still incipient, discussion on this topic in Brazil is becoming increasingly broad and necessary. With the aim of increasing knowledge and stimulating debate on LCS, the Brazilian Society of Thoracic Surgery, the Brazilian Thoracic Association, and the Brazilian College of Radiology and Diagnostic Imaging convened a panel of experts to prepare recommendations for LCS in Brazil. The recommendations presented here were based on a narrative review of the literature, with an emphasis on large population-based studies, systematic reviews, and the recommendations of international guidelines, and were developed after extensive discussion by the panel of experts. The following topics were reviewed: reasons for screening; general considerations about smoking; epidemiology of LC; eligibility criteria; incidental findings; granulomatous lesions; probabilistic models; minimum requirements for LDCT; volumetric acquisition; risks of screening; minimum structure and role of the multidisciplinary team; practice according to the Lung CT Screening Reporting and Data System; costs versus benefits of screening; and future perspectives for LCS. LC (LC tumors 15 stage 85 cases (LCS lowdose low dose (LDCT LCrelated related 20 20% 38 cessation decade populationbased population recommendation incipient necessary Surgery Association literature studies reviews guidelines reviewed criteria findings lesions models acquisition team System 1 8 2 3
8.
Influence of genetic polymorphisms on oral health-related quality of life after root canal treatment healthrelated health related
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Queiroz, Graciane E. R.
; Castilho, Thuanny
; Guimarães, Ludmila Silva
; Moraes, Vania Gomes
; Silva, Erlange Andrade Borges da
; Küchler, Erika Calvano
; Silva-Sousa, Alice Corrêa
; Sousa-Neto, Manoel Damião
; Antunes, Lívia Azeredo Alves
; Antunes, Leonardo Santos
.
Resumo Avaliar o impacto de polimorfismos genéticos em interleucinas (IL1A rs17561, rs1304037; IL10 rs1800871; IL1RN rs9005), óxido nítrico (NOS2 rs2779249, rs2897518) e supressor da sinalização de citocinas (SOCS1 rs243327, rs33977706) na qualidade de vida relacionada à saúde bucal (QVRSB) de pacientes submetidos a tratamento endodôntico (TE). Métodos: A amostra foi composta por 108 participantes, que apresentavam dentes unirradiculares com lesão periapical assintomática. O impacto da QVRSB foi registrado usando o Oral Health Impact Profile (OHIP-14) antes, sete e 30 dias após o TE. Amostras de saliva foram coletadas como fonte de DNA genômico. Os polimorfismos genéticos foram genotipados por PCR em tempo real usando o método Taqman. Análises univariadas e multivariadas foram utilizadas (p<0,05). Resultados: Observou-se diferença significativa para o polimorfismo rs2297518 no gene NOS2 na limitação funcional nos modelos codominante (p=0,037) e recessivo (p=0,001); na dor física (p<0,001 em ambos os modelos); no desconforto psicológico (p<0,001 em ambos os modelos); na deficiência física (p<0,001 em ambos os modelos) e na deficiência psicológica (p<0,001 em ambos os modelos). Polimorfismos no gene SOCS1, no modelo recessivo, rs33977706 (p=0,045) e rs243327 (p=0,019), influenciaram a QVRSB no domínio desconforto psicológico. Conclusões: Polimorfismos nos genes NOS2 e SOCS1 influenciaram a QVRSB de pacientes submetidos a TE. IL1A ILA IL rs17561 rs rs1304037 IL1 rs1800871 ILRN RN rs9005, rs9005 , rs9005) NOS (NOS rs2779249 rs2897518 SOCS (SOCS (QVRSB TE . (TE) Métodos 10 participantes assintomática OHIP14 OHIP 14 (OHIP-14 antes 3 genômico Taqman p<0,05. p005 p p<0,05 0 05 (p<0,05) Resultados Observouse Observou se rs229751 p=0,037 p0037 037 (p=0,037 p=0,001 p0001 001 (p=0,001) p<0,001 (p<0,00 modelos. rs3397770 p=0,045 p0045 045 (p=0,045 rs24332 p=0,019, p0019 p=0,019 019 (p=0,019) Conclusões rs1756 rs130403 rs180087 rs900 rs277924 rs289751 (TE 1 OHIP1 (OHIP-1 p00 p<0,0 (p<0,05 rs22975 p=0,03 p003 03 (p=0,03 p=0,00 p000 00 (p=0,001 p<0,00 (p<0,0 rs339777 p=0,04 p004 04 (p=0,04 rs2433 p001 p=0,01 01 (p=0,019 rs175 rs13040 rs18008 rs90 rs27792 rs28975 (OHIP- p0 p<0, rs2297 p=0,0 (p=0,0 (p=0,00 (p<0, rs33977 rs243 (p=0,01 rs17 rs1304 rs1800 rs9 rs2779 rs2897 (OHIP p<0 rs229 p=0, (p=0, (p<0 rs3397 rs24 rs1 rs130 rs180 rs277 rs289 p< rs22 p=0 (p=0 (p< rs339 rs2 rs13 rs18 rs27 rs28 p= (p= (p rs33 rs3
Abstract To evaluate the impact of genetic polymorphisms in interleukins (IL1A rs17561, rs1304037; IL10 rs1800871; IL1RN rs9005), nitric oxide (NOS2 rs2779249, rs2897518) and suppressor of cytokine signaling (SOCS1 rs243327, rs33977706) on oral health-related quality of life (OHRQoL) of patients under-going root canal treatment (RCT). Methods: The sample consisted of 108 participants, presenting single-rooted teeth with asymptomatic periapical periodontitis. The impact of the OHRQoL was recorded using the Oral Health Impact Profile (OHIP-14) before, seven, and 30 days after RCT. Saliva samples were collected as a source of genomic DNA. Genetic polymorphisms were genotyped by Real-Time PCR using the Taqman method. Univariate and Multivariate analyses were used (p<0.05). Results: A significant difference was observed for the polymorphism rs2297518 in the NOS2 gene in functional limitation in the codominant (p=0.037) and recessive (p=0.001) models; in the physical pain (p<0.001 in both models); in psychological discomfort (p<0.001 in both models); in physical disability (p<0.001 in both models) and in psychological disability (p<0.001 in both models). Polymorphisms in the SOCS1 gene, in the recessive model, rs33977706 (p=0.045) and rs243327 (p=0.019), influenced the OHRQoL in the psychological discomfort domain. Conclusions: Polymorphisms in NOS2 and SOCS1 genes influenced the OHRQoL of patients undergoing RCT. IL1A ILA IL rs17561 rs rs1304037 IL1 rs1800871 ILRN RN rs9005, rs9005 , rs9005) NOS (NOS rs2779249 rs2897518 SOCS (SOCS healthrelated health related (OHRQoL under going RCT . (RCT) Methods 10 participants singlerooted single rooted periodontitis OHIP14 OHIP 14 (OHIP-14 before seven 3 DNA RealTime Real Time method p<0.05. p005 p p<0.05 0 05 (p<0.05) Results rs229751 p=0.037 p0037 037 (p=0.037 p=0.001 p0001 001 (p=0.001 models p<0.001 (p<0.00 models. model rs3397770 p=0.045 p0045 045 (p=0.045 rs24332 p=0.019, p0019 p=0.019 019 (p=0.019) domain Conclusions rs1756 rs130403 rs180087 rs900 rs277924 rs289751 (RCT 1 OHIP1 (OHIP-1 p00 p<0.0 (p<0.05 rs22975 p=0.03 p003 03 (p=0.03 p=0.00 p000 00 (p=0.00 p<0.00 (p<0.0 rs339777 p=0.04 p004 04 (p=0.04 rs2433 p001 p=0.01 01 (p=0.019 rs175 rs13040 rs18008 rs90 rs27792 rs28975 (OHIP- p0 p<0. rs2297 p=0.0 (p=0.0 (p<0. rs33977 rs243 (p=0.01 rs17 rs1304 rs1800 rs9 rs2779 rs2897 (OHIP p<0 rs229 p=0. (p=0. (p<0 rs3397 rs24 rs1 rs130 rs180 rs277 rs289 p< rs22 p=0 (p=0 (p< rs339 rs2 rs13 rs18 rs27 rs28 p= (p= (p rs33 rs3
9.
Coleoptera of Brazil: what we knew then and what we know now. Insights from the Catálogo Taxonômico da Fauna do Brasil Brazil now
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Caron, Edilson
; Monné, Marcela L.
; Ferreira, Vinicius S.
; Costa, Cleide
; Cupello, Mario
; Aloquio, Sergio
; Linzmeier, Adelita M.
; Vaz-de-Mello, Fernando Z.
; Leivas, Fernando W.T.
; Souza-Gonçalves, Igor
; Mermudes, José R.M.
; Almeida, Lúcia M.
; Moura, Luciano de A.
; Ferreira Júnior, Nelson
; Grossi, Paschoal C.
; Vanin, Sergio A.
; Ślipiński, Adam
; Anichtchenko, Alexander
; Newton, Alfred F.
; Sampaio, Aline
; Carelli, Allan
; Puker, Anderson
; Ferreira, André da S.
; Fernandes, André S.
; Roza, André S.
; Cline, Andrew
; Sampaio, Brunno H.L.
; Clarkson, Bruno
; Castro, Camila F. de
; Bicho, Carla de L.
; Benetti, César J.
; Ribeiro-Costa, Cibele S.
; Lopes-Andrade, Cristiano
; Manfio, Daiara
; Colpani, Daniara
; Basílio, Daniel S.
; Bená, Daniela de C.
; Pollock, Darren A.
; Souza, Diego de S.
; Rodrigues, Diego F.
; Chandler, Donald S.
; Nascimento, Elynton A. do
; Spiessberger, Erich L.
; Agrain, Federico A.
; Barbosa, Felipe F.
; Shockley, Floyd
; Nascimento, Francisco E. de L.
; Biffi, Gabriel
; Powell, Gareth S.
; Morse, Geoffrey E.
; Flores, Gustavo E.
; Escalona, Hermes
; Quintino, Hingrid Y.S.
; Rainho, Hugo L.
; Maddalena, Italo S.C.P.
; Hájek, Jiří
; McHugh, Joseph V.
; Botero, Juan P.
; Fuhrmann, Juares
; Churata-Salcedo, Julissa M.
; Vieira, Letícia M.
; Silveira, Luiz F.L. da
; Cruz, Luiza S. da
; Sekerka, Lukás
; Bologna, Marco A.
; Bevilaqua, Marcus V.O.
; Passos, Maria I.
; Chamorro, Maria L.
; Cherman, Mariana A.
; Bento, Matheus
; Gimmel, Matthew
; Segura, Melissa O.
; Ivie, Michael A.
; Thomas, Michael C.
; Monné, Miguel A.
; Lord, Nathan
; Hamada, Neusa
; Degallier, Nicolas
; Santos, Paula B. dos
; Duarte, Paulo R.M.
; Gnaspini, Pedro
; Bulirsch, Petr
; Regalin, Renato
; Leschen, Richard A.B.
; Constantin, Robert
; Corrêa, Rodrigo C.
; Gerstmeier, Roland
; Rosa, Simone P.
; Campos, Stéphanie V.N.
; Peck, Stewart B.
; Pacheco, Thaynara L.
; Polizei, Thiago T.S.
; McElrath, Thomas C.
; Grzymala, Traci L.
; Smith, Trevor R.
; Costa-Silva, Vinicius da
; Sandoval-Gómez, Vivian E.
; Sousa, Wesley O. de
; Tomaszewska, Wioletta
.
ABSTRACT In 2000, Cleide Costa published a paper presenting the state of knowledge of the Neotropical Coleopte ra, with a focus on the Brazilian fauna. Twenty-four years later, thanks to the development of the Coleoptera section of the Taxonomic Catalog of the Brazilian Fauna (CTFB - Catálogo Taxonômico da Fauna do Brasil) through the collaboration of 100 coleopterists from all over the globe, we can build on Costa’s work and present an updated overview of the state of knowledge of the beetles from Brazil. There are currently 35,699 species in 4,958 genera and 116 families known to occur in the country, including representatives of all extant suborders and superfamilies. Our data show that the Brazilian beetle fauna is the richest on the planet, concentrating 9% of the world species diversity, with some estimates accounting to up to 15% of the global total. The most diverse family in numbers of genera is Cerambycidae (1,056 genera), while in number of species it is Chrysomelidae (6,079 species). Conotrachelus Dejean, 1835 (Curculionidae) is the most species-rich genus, with 570 species. The French entomologist Maurice Pic is the author who has contributed the most to the naming of species recorded from Brazil, with 1,794 valid names in 36 families, whereas the Brazilians Ubirajara R. Martins and Maria Helena M. Galileo are the only ones among the top-ten authors to have named species in the 21st century. Currently, approximately 144 new species of Brazilian beetles are described each year, and this average is projected to increase in the next decade to 180 species per year, or about one new Brazilian beetle every two days. 2000 ra Twentyfour Twenty four later CTFB Brasil 10 globe Costas s Brazil 35699 35 699 35,69 4958 4 958 4,95 11 country superfamilies planet 9 diversity 15 total 1,056 1056 1 056 (1,05 genera, , genera) 6,079 6079 6 079 (6,07 . species) Dejean 183 Curculionidae (Curculionidae speciesrich rich genus 57 1794 794 1,79 3 R M topten top ten st century Currently 14 year 18 days 200 3569 69 35,6 495 95 4,9 1,05 105 05 (1,0 6,07 607 07 (6,0 5 179 79 1,7 20 356 35, 49 4, 1,0 0 (1, 6,0 60 (6, 17 7 1, 2 (1 6, (6 (
10.
Catálogo Taxonômico da Fauna do Brasil: Setting the baseline knowledge on the animal diversity in Brazil Brasil
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Boeger, Walter A.
; Valim, Michel P.
; Zaher, Hussam
; Rafael, José A.
; Forzza, Rafaela C.
; Percequillo, Alexandre R.
; Serejo, Cristiana S.
; Garraffoni, André R.S.
; Santos, Adalberto J.
; Slipinski, Adam
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; Kury, Adriano B.
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; Paula, Alexandre S. de
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; Specht, Alexandre
; Camargo, Alexssandro
; Newton, Alfred F.
; Silva, Aline A.S. da
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; Wengrat, Ana P.G. da Silva
; Dornellas, Ana P.S.
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; Puker, Anderson
; Morandini, André C.
; Ferreira, André da S.
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; Brito, Ayrton do R.
; Romera, Bárbara L.V.
; Vasconcelos, Beatriz M.C. de
; Frable, Benjamin W.
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; Souto, Camilla
; Bicho, Carla de L.
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; Bonecker, Claudia C.
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; Oliveira, Cléo D.C. de
; Schwertner, Cristiano F.
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; Ferreira, Denise N.M.
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; Barbosa, Diego N.
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; Razzolini, Emanuel
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; Gallardo, Fabiana
; Hernandes, Fabio A.
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; Amaral, Fabio R.
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; Molina, Flavio B.
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; Salvatierra, Lidianne
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; Bezerra, Luis E.A.
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; Simone, Luiz R.L.
; Malabarba, Luiz R.
; Cruz, Luiza S. da
; Sekerka, Lukas
; Barros, Lurdiana D.
; Santos, Luziany Q.
; Skoracki, Maciej
; Correia, Maira A.
; Uchoa, Manoel A.
; Andrade, Manuella F.G.
; Hermes, Marcel G.
; Miranda, Marcel S.
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; Monné, Marcela L.
; Labruna, Marcelo B.
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; Nogueira, Marcelo
; Britto, Marcelo R. de
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; Loeb, Marina V.
; Cohn-Haft, Mario
; Cupello, Mario
; Martins, Marlúcia B.
; Christofersen, Martin L.
; Bento, Matheus
; Rocha, Matheus dos S.
; Martins, Maurício L.
; Segura, Melissa O.
; Cardenas, Melissa Q.
; Duarte, Mércia E.
; Ivie, Michael A.
; Mincarone, Michael M.
; Borges, Michela
; Monné, Miguel A.
; Casagrande, Mirna M.
; Fernandez, Monica A.
; Piovesan, Mônica
; Menezes, Naércio A.
; Benaim, Natalia P.
; Reategui, Natália S.
; Pedro, Natan C.
; Pecly, Nathalia H.
; Ferreira Júnior, Nelson
; Silva Júnior, Nelson J. da
; Perioto, Nelson W.
; Hamada, Neusa
; Degallier, Nicolas
; Chao, Ning L.
; Ferla, Noeli J.
; Mielke, Olaf H.H.
; Evangelista, Olivia
; Shibatta, Oscar A.
; Oliveira, Otto M.P.
; Albornoz, Pablo C.L.
; Dellapé, Pablo M.
; Gonçalves, Pablo R.
; Shimabukuro, Paloma H.F.
; Grossi, Paschoal
; Rodrigues, Patrícia E. da S.
; Lima, Patricia O.V.
; Velazco, Paul
; Santos, Paula B. dos
; Araújo, Paula B.
; Silva, Paula K.R.
; Riccardi, Paula R.
; Garcia, Paulo C. de A.
; Passos, Paulo G.H.
; Corgosinho, Paulo H.C.
; Lucinda, Paulo
; Costa, Paulo M.S.
; Alves, Paulo P.
; Roth, Paulo R. de O.
; Coelho, Paulo R.S.
; Duarte, Paulo R.M.
; Carvalho, Pedro F. de
; Gnaspini, Pedro
; Souza-Dias, Pedro G.B.
; Linardi, Pedro M.
; Bartholomay, Pedro R.
; Demite, Peterson R.
; Bulirsch, Petr
; Boll, Piter K.
; Pereira, Rachel M.M.
; Silva, Rafael A.P.F.
; Moura, Rafael B. de
; Boldrini, Rafael
; Silva, Rafaela A. da
; Falaschi, Rafaela L.
; Cordeiro, Ralf T.S.
; Mello, Ramon J.C.L.
; Singer, Randal A.
; Querino, Ranyse B.
; Heleodoro, Raphael A.
; Castilho, Raphael de C.
; Constantino, Reginaldo
; Guedes, Reinaldo C.
; Carrenho, Renan
; Gomes, Renata S.
; Gregorin, Renato
; Machado, Renato J.P.
; Bérnils, Renato S.
; Capellari, Renato S.
; Silva, Ricardo B.
; Kawada, Ricardo
; Dias, Ricardo M.
; Siewert, Ricardo
; Brugnera, Ricaro
; Leschen, Richard A.B.
; Constantin, Robert
; Robbins, Robert
; Pinto, Roberta R.
; Reis, Roberto E. dos
; Ramos, Robson T. da C.
; Cavichioli, Rodney R.
; Barros, Rodolfo C. de
; Caires, Rodrigo A.
; Salvador, Rodrigo B.
; Marques, Rodrigo C.
; Araújo, Rodrigo C.
; Araujo, Rodrigo de O.
; Dios, Rodrigo de V.P.
; Johnsson, Rodrigo
; Feitosa, Rodrigo M.
; Hutchings, Roger W.
; Lara, Rogéria I.R.
; Rossi, Rogério V.
; Gerstmeier, Roland
; Ochoa, Ronald
; Hutchings, Rosa S.G.
; Ale-Rocha, Rosaly
; Rocha, Rosana M. da
; Tidon, Rosana
; Brito, Rosangela
; Pellens, Roseli
; Santos, Sabrina R. dos
; Santos, Sandra D. dos
; Paiva, Sandra V.
; Santos, Sandro
; Oliveira, Sarah S. de
; Costa, Sávio C.
; Gardner, Scott L.
; Leal, Sebastián A. Muñoz
; Aloquio, Sergio
; Bonecker, Sergio L.C.
; Bueno, Sergio L. de S.
; Almeida, Sérgio M. de
; Stampar, Sérgio N.
; Andena, Sérgio R.
; Posso, Sergio R.
; Lima, Sheila P.
; Gadelha, Sian de S.
; Thiengo, Silvana C.
; Cohen, Simone C.
; Brandão, Simone N.
; Rosa, Simone P.
; Ribeiro, Síria L.B.
; Letana, Sócrates D.
; Santos, Sonia B. dos
; Andrade, Sonia C.S.
; Dávila, Stephane
; Vaz, Stéphanie
; Peck, Stewart B.
; Christo, Susete W.
; Cunha, Suzan B.Z.
; Gomes, Suzete R.
; Duarte, Tácio
; Madeira-Ott, Taís
; Marques, Taísa
; Roell, Talita
; Lima, Tarcilla C. de
; Sepulveda, Tatiana A.
; Maria, Tatiana F.
; Ruschel, Tatiana P.
; Rodrigues, Thaiana
; Marinho, Thais A.
; Almeida, Thaís M. de
; Miranda, Thaís P.
; Freitas, Thales R.O.
; Pereira, Thalles P.L.
; Zacca, Thamara
; Pacheco, Thaynara L.
; Martins, Thiago F.
; Alvarenga, Thiago M.
; Carvalho, Thiago R. de
; Polizei, Thiago T.S.
; McElrath, Thomas C.
; Henry, Thomas
; Pikart, Tiago G.
; Porto, Tiago J.
; Krolow, Tiago K.
; Carvalho, Tiago P.
; Lotufo, Tito M. da C.
; Caramaschi, Ulisses
; Pinheiro, Ulisses dos S.
; Pardiñas, Ulyses F.J.
; Maia, Valéria C.
; Tavares, Valeria
; Costa, Valmir A.
; Amaral, Vanessa S. do
; Silva, Vera C.
; Wolff, Vera R. dos S.
; Slobodian, Verônica
; Silva, Vinícius B. da
; Espíndola, Vinicius C.
; Costa-Silva, Vinicius da
; Bertaco, Vinicius de A.
; Padula, Vinícius
; Ferreira, Vinicius S.
; Silva, Vitor C.P. da
; Piacentini, Vítor de Q.
; Sandoval-Gómez, Vivian E.
; Trevine, Vivian
; Sousa, Viviane R.
; Sant’Anna, Vivianne B. de
; Mathis, Wayne N.
; Souza, Wesley de O.
; Colombo, Wesley D.
; Tomaszewska, Wioletta
; Wosiacki, Wolmar B.
; Ovando, Ximena M.C.
; Leite, Yuri L.R.
.
ABSTRACT The limited temporal completeness and taxonomic accuracy of species lists, made available in a traditional manner in scientific publications, has always represented a problem. These lists are invariably limited to a few taxonomic groups and do not represent up-to-date knowledge of all species and classifications. In this context, the Brazilian megadiverse fauna is no exception, and the Catálogo Taxonômico da Fauna do Brasil (CTFB) (http://fauna.jbrj.gov.br/), made public in 2015, represents a database on biodiversity anchored on a list of valid and expertly recognized scientific names of animals in Brazil. The CTFB is updated in near real time by a team of more than 800 specialists. By January 1, 2024, the CTFB compiled 133,691 nominal species, with 125,138 that were considered valid. Most of the valid species were arthropods (82.3%, with more than 102,000 species) and chordates (7.69%, with over 11,000 species). These taxa were followed by a cluster composed of Mollusca (3,567 species), Platyhelminthes (2,292 species), Annelida (1,833 species), and Nematoda (1,447 species). All remaining groups had less than 1,000 species reported in Brazil, with Cnidaria (831 species), Porifera (628 species), Rotifera (606 species), and Bryozoa (520 species) representing those with more than 500 species. Analysis of the CTFB database can facilitate and direct efforts towards the discovery of new species in Brazil, but it is also fundamental in providing the best available list of valid nominal species to users, including those in science, health, conservation efforts, and any initiative involving animals. The importance of the CTFB is evidenced by the elevated number of citations in the scientific literature in diverse areas of biology, law, anthropology, education, forensic science, and veterinary science, among others. publications problem uptodate up date classifications context exception (CTFB http//fauna.jbrj.gov.br/, httpfaunajbrjgovbr http //fauna.jbrj.gov.br/ , jbrj gov br (http://fauna.jbrj.gov.br/) 2015 Brazil 80 specialists 1 2024 133691 133 691 133,69 125138 125 138 125,13 82.3%, 823 82 3 (82.3% 102000 102 000 102,00 7.69%, 769 7 69 (7.69% 11000 11 11,00 . 3,567 3567 567 (3,56 2,292 2292 2 292 (2,29 1,833 1833 833 (1,83 1,447 1447 447 (1,44 1000 1,00 831 (83 628 (62 606 (60 520 (52 50 users science health biology law anthropology education others http//fauna.jbrj.gov.br/ faunajbrjgovbr //fauna.jbrj.gov.br (http://fauna.jbrj.gov.br/ 201 8 202 13369 13 133,6 12513 12 125,1 82.3% (82.3 10200 10 00 102,0 7.69% 76 6 (7.69 1100 11,0 3,56 356 56 (3,5 2,29 229 29 (2,2 1,83 183 83 (1,8 1,44 144 44 (1,4 100 1,0 (8 62 (6 60 52 (5 5 http//fauna.jbrj.gov.br (http://fauna.jbrj.gov.br 20 1336 133, 1251 125, 82.3 (82. 1020 0 102, 7.69 (7.6 110 11, 3,5 35 (3, 2,2 22 (2, 1,8 18 (1, 1,4 14 4 ( 82. (82 7.6 (7. 3, (3 2, (2 (1 7. (7
11.
EVALUATION OF CLIMATE CHANGE IMPACTS ON SUGARCANE AND CITRUS CROPS IN BRAZIL
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Sousa, A.S.
; Xavier, F.
; Galvani, E.
; Silva, R.F.
; Mostaço, G.M.
; Saraiva, A.M.
; Cugnasca, C.E.
; Ross, J.LS.
.
Resumo A produção agrícola está diretamente relacionada às condições ambientais. Condições favoráveis podem levar a maior produtividade e qualidade do produto. No entanto, as alterações climáticas podem representar uma ameaça para a produção agrícola em todo o mundo, uma vez que um aumento da temperatura pode causar uma diminuição na extensão de áreas adequadas para o cultivo de certas culturas. Utilizando análises espaciais e dados de cenários futuros de mudanças climáticas desenvolvidos pelo Painel Intergovernamental sobre Mudanças Climáticas, este estudo teve como objetivo avaliar o impacto das mudanças climáticas nas plantações de cana-de-açúcar e citros no estado de São Paulo por meio do mapeamento do zoneamento agroclimático. Os resultados deste estudo demonstram que ambas as culturas podem sofrer grandes reduções nas áreas aptas ao cultivo caso haja mudanças severas no regime climático. Essas descobertas podem auxiliar gestores e pesquisadores a mitigar esses potenciais impactos e esclarecer como as mudanças climáticas afetam a vida no planeta, com potencial redução na produção de alimentos e bioenergia. ambientais produto entanto mundo Climáticas canadeaçúcar cana açúcar agroclimático climático planeta bioenergia
Abstract Agricultural production is directly related to environmental conditions. Favorable conditions can lead to higher productivity and product quality. However, climate change may pose a threat to agricultural production worldwide, as an increase in temperature may cause a decrease in the extent of suitable areas for growing certain crops. Using spatial analysis and data from future climate change scenarios developed by the Intergovernmental Panel on Climate Change, this study aimed to evaluate the impact of climate change on sugarcane and citrus plantations in the state of São Paulo using agroclimatic zoning mapping. The results of this study demonstrate that both crops can suffer major reductions in areas suitable for cultivation if there are severe changes in the climate regime. These findings can assist managers and researchers to mitigate these potential impacts and clarify how climate change affects life on the planet, with a potential reduction in food and bioenergy production. quality However worldwide Change mapping regime planet
Resumen La producción agrícola está directamente relacionada con las condiciones ambientales. Las condiciones favorables pueden conducir a una mayor productividad y calidad del producto. Sin embargo, el cambio climático puede representar una amenaza para la producción agrícola en todo el mundo, ya que un aumento de la temperatura puede causar una disminución en la extensión de las áreas adecuadas para el cultivo de ciertos cultivos. Utilizando análisis espaciales y datos de escenarios futuros de cambio climático desarrollados por el Panel Intergubernamental sobre Cambio Climático, este estudio tuvo como objetivo evaluar el impacto del cambio climático en las plantaciones de caña de azúcar y cítricos en el estado de São Paulo mediante mapeo de zonificación agroclimática. Los resultados de este estudio demuestran que ambos cultivos pueden sufrir importantes reducciones en las superficies aptas para el cultivo si se producen cambios severos en el régimen climático. Estos hallazgos pueden ayudar a los administradores e investigadores a mitigar estos impactos potenciales y aclarar cómo el cambio climático afecta la vida en el planeta, con una reducción potencial en la producción de alimentos y bioenergía. ambientales producto embargo mundo Climático agroclimática planeta bioenergía
12.
Influence of minimally invasive cavities on color stability of dental crowns with different filling sealers
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Silva-Sousa, Alice Corrêa
; Sousa-Neto, Manoel Damião
; Camargo, Rafael Verardino
; Lima, Thamires Diogo
; Branco, Antônio Castelo
; Pires-De-Souza, Fernanda de Carvalho Panzeri
; Faria-E-Silva, André Luís
; Paula-Silva, Francisco Wanderley Garcia
; Roperto, Renato
; Souza-Gabriel, Aline Evangelista
; Mazzi-Chaves, Jardel Francisco
.
Abstract: The minimally invasive endodontic access is not directly associated with tooth discoloration in the presence of bioceramic or epoxy resin-based root canal sealers. This study aimed to evaluate the influence of minimally invasive access and endodontic sealer composition on the color stability of endodontically-treated teeth, the restorative material adaptation, and the presence of remaining filling material in the pulp chamber. Endodontic access surgery was performed in maxillary central incisors, either through conservative or minimally invasive approaches, and the root was filled with AH Plus or Bio-C Sealer. The crown color was measured with a spectrophotometer at baseline and after root obturation, restoration, and specimen storage for one year in an oven. The occurrence of voids in the restoration and the remaining filling material was analyzed using micro-CT scans. The Yellowness Index (YI) and color changes (∆E00) were calculated after each color measurement. Data of micro-CT were submitted to 2-way ANOVA, and YI and ∆E00 were analyzed with repeated-measures ANOVA. Pair-wise comparisons were performed with Tukey's test (α = 0.05). The experimental conditions had no effect on the presence of the remaining material. The minimally invasive access associated with Bio-C Sealer resulted in more voids between the restoration and the remaining filling material. Only the evaluation time affected YI and ∆E00 values. Specimens became more yellow after filling and storage in the oven (the highest ∆E00 values). The present study showed that sealer and minimally invasive cavities are not associated with crown color stability following endodontic treatment. Abstract resinbased resin based sealers endodonticallytreated endodontically treated teeth adaptation chamber incisors approaches BioC Bio C obturation microCT micro CT scans (YI E00 E (∆E00 measurement 2way way 2 ANOVA ∆E0 repeatedmeasures repeated measures Pairwise Pair wise Tukeys Tukey s α 0.05. 005 0.05 . 0 05 0.05) values values) treatment E0 (∆E0 ∆E 00 0.0 (∆E 0.
13.
Antifungal action of essential oils against Fusarium rot in melon
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Sousa, Aline E. D. de
; Melo, Rafaela P.
; Gagliardi, Paulo R.
; Nunes, Glauber H. de S
; Oster, Andreia H.
; Silva, Ebenézer de O.
.
RESUMO Objetivou-se com esse trabalho determinar a composição e avaliar, ‘in vitro’ e ‘in vivo’, o efeito dos óleos essenciais de alecrim-pimenta (Lippia sidoides Cham.), alfavacacravo (Ocimum gratissimum L.), capim-limão (Cymbopogon citratus Stapf.), elixir-paregórico (Ocimum selloi Benth.), laranja (Citrus sinensis L.), manjericão (Ocimum micranthum Willd.), Ocimum sp. e pimenta-de-macaco (Piper aduncum L.) no controle da podridão por Fusarium causada pelo fungo Fusarium pallidoroseum em frutos de melão. Os óleos essenciais foram obtidos por hidrodestilação e a composição química determinada por GC-MS e GC-FID. No ensaio ‘in vitro’, foi testado o efeito de cada óleo essencial (concentrações de 0, 500, 1500 e 3000µL/L) sobre o crescimento micelial do patógeno. Determinou-se a concentração efetiva que inibiu o crescimento micelial em 50% (EC50) pelo método de probit e o Índice de Crescimento Micelial (ICM). Os óleos essenciais com maior potencial inibidor no crescimento micelial do F. pallidoroseum foram avaliados quanto ao efeito inibitório na germinação de esporos do fungo no ensaio ‘in vitro’ e ‘in vivo’ com frutos de melão ‘Galia’. A análise da composição química possibilitou a identificação de quantidades variáveis de compostos químicos, com predominância dos compostos monoterpênicos. Os óleos essenciais de alecrimpimenta, alfavaca-cravo, capim-limão e manjericão, apresentaram melhores efeitos na inibição do crescimento micelial e germinação dos esporos do fungo, mostrando-se promissores como matériaprima para o desenvolvimento de fungicidas comerciais, em especial no controle de podridão causada por F. pallidoroseum, em póscolheita. Objetivouse Objetivou se avaliar in vitro vivo, vivo , alecrimpimenta alecrim pimenta Lippia Cham., Cham Cham. Cham.) L., L L. capimlimão capim limão Cymbopogon Stapf., Stapf Stapf. Stapf.) elixirparegórico elixir paregórico Benth., Benth Benth. Benth.) Citrus Willd., Willd Willd. Willd.) sp pimentademacaco macaco Piper GCMS GC MS GCFID. GCFID FID. FID GC-FID vitro, concentrações 0 500 150 3000µL/L 3000µLL µLL 3000µL µL patógeno Determinouse Determinou 50 EC50 EC (EC50 ICM. ICM . (ICM) F ‘Galia. Galia ‘Galia ‘Galia’ químicos monoterpênicos alfavacacravo, alfavaca cravo, cravo alfavaca-cravo mostrandose mostrando comerciais póscolheita 15 5 EC5 (EC5 (ICM 1 (EC
ABSTRACT The objective of this work was to determine the composition and evaluate in vitro and in vivo effects of essential oils (Lippia sidoides Cham., Ocimum gratissimum L., Cymbopogon citratus Stapf., Ocimum selloi Benth., Citrus sinensis L., Ocimum micranthum Willd., Ocimum sp., and Piper aduncum L.) on the control of Fusarium rot in melon fruits, caused by the fungus Fusarium pallidoroseum. The essential oils were obtained by hydrodistillation and their chemical composition was determined by GCMS and GC-FID. The effect of each essential oil (concentrations of 0, 500, 1500, and 3000µL L-1) on the fungal mycelial growth was evaluated in in vitro experiment. The effective concentration that inhibited 50% of mycelial growth (EC50) was determined through the probit method; mycelial growth index (MGI) was also calculated. The essential oils with higher potential for inhibiting mycelial growth of F. pallidoroseum were evaluated for their inhibitory effect on the fungus spore germination in in vitro and in vivo experiments using melon fruits (variety Galia). Chemical composition analysis of essential oils enabled the identification of varying amounts of chemical compounds, with predominance of monoterpenes. The essential oils of L. sidoides, O. gratissimum, C. citratus, and O. micranthum presented higher inhibiting effects on F. pallidoroseum mycelial growth and spore germination, therefore, they are promising raw materials for the development of commercial fungicides, mainly for controlling postharvest rot caused by F. pallidoroseum. Lippia Cham Cham. L Stapf Stapf. Benth Benth. Willd Willd. sp sp. GCFID. GCFID GC FID. FID GC-FID concentrations 0 500 1500 µL L1 1 L-1 experiment 50 EC50 EC (EC50 method MGI (MGI calculated F variety Galia. Galia . Galia) compounds monoterpenes O C therefore fungicides 150 L- 5 EC5 (EC5 15 (EC
14.
Scientists of Tomorrow/ Cientistas do Amanhã : a project to inspire, stimulate scientific thinking, and introduce scientific methodology for young students Tomorrow inspire thinking
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Rangel, Érika Bevilaqua
; Silva, André Luiz Teles e
; Vidal, Érica Kássia de Sousa
; Tomaz, Victória
; Watanabe, Caroline Mitiká
; Beyerstedt, Stephany
; Sales, Romário Oliveira de
; Santana Junior, Eliezer Francisco de
; Leão, Rômulo Gonçalves
; Cancello, Pedro
; Aloia, Thiago Pinheiro Arrais
; Silva, Jaciele Conceição da
; Almeida, Laudiceia
; Oliveira, Letícia Bernardes de
; Cintra, Luciana
; Hernandes, Camila
; Gamarra, Lionel Fernel
; Leão, Eliseth Ribeiro
; Klajner, Sidney
; Rizzo, Luiz Vicente
.
ABSTRACT The Scientists of Tomorrow/ Cientistas do Amanhã project is an immersive science training program developed by the Program of Post-Graduation in Health Sciences at Hospital Israelita Albert Einstein. This program was conducted in partnership with Volunteering and Escola Municipal de Ensino Fundamental Professor Paulo Freire in Paraisópolis, São Paulo, Brazil. The Scientists of Tomorrow Program comprised a short training period conducted in May 2022 involving 37 students, and a long training period from August to December 2022, which included 15 students. It aimed to popularize science through practical activities; transfer knowledge to young students; sensitize and guide them to pursue academic-scientific careers; reduce stereotypes about scientific work and scientists; and help students understand the social, political, and ethical roles of science within society. All activities were led by postgraduate students and professors from our postgraduate program, physicians, nurses, physiotherapists, biomedicals, and veterinarians from Hospital Israelita Albert Einstein, as well as medical students from Faculdade Israelita de Ciências da Saúde Albert Einstein . Activities in the short training included lectures on cinema and science, strategies to combat fake news, non-violent communication, innovation, design-thinking framework, and developing a scientific project. During the long training period, discussions were focused on nanotechnology, animal research, big data, bioinformatics, meditation, blood and bone marrow donation, telemedicine, sex and sexually-transmitted infections, rehabilitation, career opportunities, and scientific integrity. In addition, practical activities were further expanded using optical and confocal microscopy, cytometry, and basic concepts regarding the structure and function of living cells. The program also included the launching of the open-air outreach Education E-natureza activity, which turned students into ambassadors of nature. In conclusion, the Scientists of Tomorrow Program was innovative and enabled young students to learn that science is a collective activity that can enhance public health. PostGraduation Post Graduation Paraisópolis Brazil 202 3 1 academicscientific academic careers scientists social political society physicians nurses physiotherapists biomedicals news nonviolent non violent communication innovation designthinking design thinking framework nanotechnology research data bioinformatics meditation donation telemedicine sexuallytransmitted sexually transmitted infections rehabilitation opportunities integrity addition microscopy cytometry cells openair open air Enatureza E natureza nature conclusion health 20 2
15.
Emotional, hyperactivity and inattention problems in adolescents with immunocompromising chronic diseases during the COVID-19 pandemic Emotional COVID19 COVID 19 COVID-1 COVID1 1 COVID-
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Campos, Reinan T.
; Lindoso, Livia
; Sousa, Renan A. de
; Helito, Alberto C.
; Ihara, Bianca P.
; Strabelli, Claudia A.A.
; Paradelas, Levi M.V.
; Carneiro, Beatriz O.L.
; Cardoso, Maria Paula R.
; Souza, Jean Paulo V. de
; Freire, Marianna R. de M.
; Astley, Camilla
; Laurentino, Moisés F.
; Buscatti, Izabel M.
; Kozu, Katia
; Aikawa, Nadia E.
; Sallum, Adriana M.E.
; Ferreira, Juliana CO.
; Simon, Juliana R.
; Viana, Vivianne S.L.
; Queiroz, Ligia B.
; Gualano, Bruno
; Roschel, Hamilton
; Pereira, Rosa Maria R.
; Toma, Ricardo K.
; Watanabe, Andréia
; Grangeiro, Patricia M.
; Casella, Caio B.
; Farhat, Sylvia C.
; Polanczyk, Guilherme V.
; Campos, Lucia Maria A.
; Silva, Clovis A.
.
Abstract Objective: To assess factors associated with emotional changes and Hyperactivity/Inattention (HI) motivated by COVID-19 quarantine in adolescents with immunocompromising diseases. Methods: A cross-sectional study included 343 adolescents with immunocompromising diseases and 108 healthy adolescents. Online questionnaires were answered including socio-demographic data and self-rated healthcare routine during COVID-19 quarantine and validated surveys: Strengths and Difficulties Questionnaire (SDQ), Pittsburgh Sleep Quality Index (PSQI), Pediatric Quality of Life Inventory 4.0 (PedsQL4.0). Results: The frequencies of abnormal emotional SDQ scores from adolescents with chronic diseases were similar to those of healthy subjects (110/343 [32%] vs. 38/108 [35%], p = 0.548), as well as abnormal hyperactivity/inattention SDQ scores (79/343 [23%] vs. 29/108 [27%], p = 0.417). Logistic regression analysis of independent variables associated with abnormal emotional scores from adolescents with chronic diseases showed: female sex (Odds Ratio [OR = 3.76]; 95% Confidence Interval (95% CI) 2.00–7.05; p < 0.001), poor sleep quality (OR = 2.05; 95% CI 1.08–3.88; p = 0.028) and intrafamilial violence during pandemic (OR = 2.17; 95% CI 1.12–4.19; p = 0.021) as independently associated with abnormal emotional scores, whereas total PedsQL score was inversely associated with abnormal emotional scores (OR = 0.95; 95% CI 0.93–0.96; p < 0.0001). Logistic regression analysis associated with abnormal HI scores from patients evidenced that total PedsQL score (OR = 0.97; 95% CI 0.95–0.99; p = 0.010], changes in medical appointments during the pandemic (OR = 0.39; 95% CI 0.19–0.79; p = 0.021), and reliable COVID-19 information (OR = 0.35; 95% CI 0.16–0.77; p = 0.026) remained inversely associated with abnormal HI scores. Conclusion: The present study showed emotional and HI disturbances in adolescents with chronic immunosuppressive diseases during the COVID-19 pandemic. It reinforces the need to promptly implement a longitudinal program to protect the mental health of adolescents with and without chronic illnesses during future pandemics. Objective HyperactivityInattention Hyperactivity Inattention (HI COVID19 COVID 19 COVID-1 Methods crosssectional cross sectional 34 10 sociodemographic socio demographic selfrated self rated surveys SDQ, , (SDQ) PSQI, PSQI (PSQI) 40 4 0 4. PedsQL4.0. PedsQL40 PedsQL4.0 . PedsQL4 (PedsQL4.0) Results 110/343 110343 110 (110/34 32% 32 [32% vs 38108 38 38/10 35%, 35 35% [35%] 0.548, 0548 0.548 548 0.548) hyperactivityinattention hyperactivity inattention 79/343 79343 79 (79/34 23% 23 [23% 29108 29 29/10 27%, 27 27% [27%] 0.417. 0417 0.417 417 0.417) Odds OR 3.76 376 3 76 3.76] 95 (95 2.00–7.05 200705 2 00 7 05 0.001, 0001 0.001 001 0.001) 2.05 205 1.08–3.88 108388 1 08 88 0.028 0028 028 2.17 217 17 1.12–4.19 112419 12 0.021 0021 021 0.95 095 0.93–0.96 093096 93 96 0.0001. 00001 0.0001 0.0001) 0.97 097 97 0.95–0.99 095099 99 0.010, 0010 0.010 010 0.010] 0.39 039 39 0.19–0.79 019079 0.021, 0.35 035 0.16–0.77 016077 16 77 0.026 0026 026 Conclusion pandemics COVID1 COVID- (SDQ (PSQI PedsQL4. (PedsQL4.0 110/34 11034 11 (110/3 [32 3810 38/1 [35% 054 0.54 54 79/34 7934 (79/3 [23 2910 29/1 [27% 041 0.41 41 3.7 37 9 (9 2.00–7.0 20070 000 0.00 2.0 20 1.08–3.8 10838 8 0.02 002 02 2.1 21 1.12–4.1 11241 0.9 09 0.93–0.9 09309 0000 0.000 0.95–0.9 09509 0.01 01 0.3 03 0.19–0.7 01907 0.16–0.7 01607 (PedsQL4. 110/3 1103 (110/ [3 381 38/ [35 0.5 5 79/3 793 (79/ [2 291 29/ [27 04 0.4 3. ( 2.00–7. 2007 0.0 2. 1.08–3. 1083 1.12–4. 1124 0. 0.93–0. 0930 0.95–0. 0950 0.19–0. 0190 0.16–0. 0160 (PedsQL4 110/ (110 [ 79/ (79 2.00–7 200 1.08–3 1.12–4 112 0.93–0 093 0.95–0 0.19–0 019 0.16–0 016 (PedsQL (11 (7 2.00– 1.08– 1.12– 0.93– 0.95– 0.19– 0.16– (1 2.00 1.08 1.12 0.93 0.19 0.16 1.0 1.1 0.1 1.
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