Resumen Objetivo Elaborar y validar el contenido de un prototipo de aplicación móvil sobre la prevención de úlcera por presión (UP) para cuidadores de personas mayores. Métodos Estudio metodológico de producción tecnológica de prototipo en aplicación móvil. El desarrollo de la aplicación fue guiado por el modelo de diseño educativo contextualizado (DEC). La etapa de validación de contenido fue realizada por siete enfermeros docentes de un curso técnico para cuidadores de personas mayores de una institución educativa nacional, mediante la aplicación del instrumento Suitability Assessement of Materials (SAM). Los datos se analizaron con estadística descriptiva. Resultados El prototipo, que fue llamado LPPrev, contiene información sobre el concepto, estadificación, causas de la UP, principales lugares de acometimiento, además de recordatorios para reposicionar a la persona mayor en la cama. También tiene la posibilidad de registrar información nutricional, hidratación oral, higiene corporal e íntima y dispone de instrucciones sobre cuidados preventivos. La evaluación de contenido obtuvo un 96,6 % de concordancia entre los docentes, por lo que es considerado un material de calidad superior. Conclusión El LPPrev es un prototipo de aplicación bien estructurado según las categorías evaluadas por el SAM, con información relevante para los cuidadores de personas mayores encamadas y dependientes. Contribuye para el conocimiento teórico y los cuidados fundamentales para la prevención de úlcera por presión y está preparado para avanzar hacia las siguientes etapas del modelo de DEC. UP (UP DEC . (DEC) nacional SAM. SAM (SAM) descriptiva concepto estadificación acometimiento cama nutricional oral preventivos 966 96 6 96, superior dependientes (DEC (SAM 9

Resumo Objetivo Desenvolver e validar o conteúdo de um protótipo de aplicativo móvel sobre Prevenção de Lesão por Pressão (LP) para cuidadores de idosos. Métodos Estudo metodológico de produção tecnológica do tipo protótipo em aplicativo móvel. O desenvolvimento do aplicativo foi guiado pelo modelo de Design Instrucional Contextualizado (DIC). A etapa de validação de conteúdo foi realizada com sete enfermeiros docentes de um curso técnico para cuidador de idosos em uma instituição federal de ensino com a aplicação do instrumento Suitability Assessement of Materials (SAM). Os dados foram analisados usando a estatística descritiva. Resultados O protótipo, que foi nomeado LPPrev, contém informações sobre conceito, estadiamento, causas das LP, principais locais de acometimento, além de lembretes para reposicionar o idoso no leito; há também possibilidade de registro de informações nutricionais, hidratação oral, higiene corporal e íntima e disponibilização de orientações sobre cuidados preventivos. A avaliação de conteúdo obteve 96,6% de concordância entre os docentes, sendo considerado um material de qualidade superior. Conclusão O LPPrev é um protótipo de aplicativo adequadamente estruturado segundo as categorias avaliadas pelo SAM, com informações relevantes aos cuidadores de idosos acamados e dependentes, contribuindo para o conhecimento teórico e cuidados fundamentais na prevenção de lesão por pressão, estando preparado para avançar para as demais etapas do modelo de DIC. LP (LP DIC . (DIC) SAM. SAM (SAM) descritiva conceito estadiamento acometimento leito nutricionais oral preventivos 966 96 6 96,6 superior dependentes pressão (DIC (SAM 9 96,

Abstract Objective To develop and validate the content of a mobile application prototype on Pressure Injury (PI) Prevention for elderly caregivers. Methods Methodological study of prototype-type technological production in mobile application. The application development was guided by the Contextualized Instructional Design (CID) model. The content validation stage was carried out by seven teaching nurses of a technical course for elderly caregivers in a federal educational institution with the application of the Suitability Assessment of Materials (SAM) instrument. Data were analyzed using descriptive statistics. Results The prototype, which was named LPPrev, contains information about the concept, staging, causes of LP, and main affecting sites, in addition to reminders to reposition the elderly in bed; registration of nutritional information, oral hydration, body and intimate hygiene, and guidance on preventive care is also possible. The content evaluation obtained 96.6% of agreement between professors, being considered a material of superior quality. Conclusion LPPrev is an application prototype properly structured according to the categories evaluated by the SAM, with relevant information for caregivers of bedridden and dependent elderly, contributing to theoretical knowledge and fundamental care in the prevention of injury by pressure, being prepared to move on to the other stages of the DIC model. PI (PI prototypetype type CID (CID model SAM (SAM instrument statistics concept staging LP sites bed hydration hygiene possible 966 96 6 96.6 professors quality pressure 9 96.

ABSTRACT Objective: To measure the costs of preventive and therapeutic protocols of Photobiomodulation (PBM) for oral mucositis (OM) and their budgetary impact on Brazil’s Ministry of Health (BMH). Material and Methods: A partial economic analysis was performed to estimate the costs using a bottom-up approach from a social perspective. Monetary values were assigned in Brazilian reais (BRL). The costs of the preventive protocol were calculated for five, 30, and 33 consecutive PBM sessions, depending on the antineoplastic treatment instituted. The costs of the therapeutic protocol were calculated for 5 or 10 sessions. The annual financial and budgetary impact was calculated considering the groups of oncologic patients with a higher risk of development of OM, such as those with head and neck and hematological cancer and pediatric patients. Results: The cost of a PBM session was estimated at BRL 23.75. The financial impact of providing one preventive protocol per year for all oncologic patients would be BRL 14,282,680.00, 0.030% of the estimated budget for hospital and outpatient care of the BMH in 2022. The financial and budgetary impacts of providing one treatment for OM for all patients in one year would be BRL 2,225,630.31 (0.005%, most optimistic scenario) and BRL 4,451,355.63 (0.009%, most pessimistic scenario). Conclusion: The budgetary impact of implementing PBM protocols in the Brazilian Healthcare System is small, even in a pessimistic scenario. Objective (PBM (OM Brazils Brazil s BMH. . (BMH) Methods bottomup bottom up perspective BRL. (BRL) five 30 3 sessions instituted 1 Results 2375 23 75 23.75 1428268000 14 282 680 00 14,282,680.00 0030 0 030 0.030 2022 222563031 2 225 630 31 2,225,630.3 0.005%, 0005 005 (0.005% scenario 445135563 4 451 355 63 4,451,355.6 0.009%, 0009 009 (0.009% Conclusion small (BMH (BRL 237 7 23.7 142826800 28 68 14,282,680.0 003 03 0.03 202 22256303 22 2,225,630. 0.005% 000 (0.005 44513556 45 35 6 4,451,355. 0.009% (0.009 23. 14282680 14,282,680. 0.0 20 2225630 2,225,630 0.005 (0.00 4451355 4,451,355 0.009 1428268 14,282,680 0. 222563 2,225,63 0.00 (0.0 445135 4,451,35 142826 14,282,68 22256 2,225,6 (0. 44513 4,451,3 14282 14,282,6 2225 2,225, (0 4451 4,451, 1428 14,282, 222 2,225 ( 445 4,451 142 14,282 2,22 44 4,45 14,28 2,2 4,4 14,2 2, 4, 14,

Resumo Introdução: As doenças respiratórias agudas apresentam difícil mensuração e contribuem para o grande número de causas de óbito mal definidas, o que afeta a confiabilidade das informações de mortalidade. Objetivo: Verificar a acurácia da definição da causa básica de óbito para doenças respiratórias agudas dos óbitos registrados no Sistema de Informações sobre Mortalidade do Distrito Federal em 2018. Método: Foi realizado um estudo de acurácia, com amostra mínima de 331 declarações de óbito com as causas de óbito do capítulo 10 (doenças do aparelho respiratório — J00-J99 — conforme subcategorias) da Classificação Internacional de Doenças na versão 10, considerando a definição de causa básica de óbito pela equipe de investigação como o padrão-ouro. Foram calculadas a sensibilidade, especificidade, valores preditivos positivo e negativo e as razões de verossimilhanças positivas e negativas com os respectivos intervalos de confiança a 95%. Resultados: Total de 396 declarações de óbito foram incluídas. Foi constatada alta sensibilidade para identificar doenças pulmonares agudas nas causas básicas de óbito (82,8%. IC95% 78,6–86,5) e alta especificidade (93,1%. IC95% 77,2–99,2). A probabilidade de a declaração apresentar resultado falso negativo foi baixa (0,2. IC95% 0,1–0,2). Conclusão: As declarações de óbito por doenças respiratórias agudas apresentaram bons resultados para acurácia e incitam a realização de estudos semelhantes para outras condições. Introdução definidas mortalidade Objetivo 2018 Método 33 1 J00J99 JJ J00 J99 J J00-J9 subcategorias padrãoouro. padrãoouro padrão ouro. ouro padrão-ouro 95 95% Resultados 39 incluídas 82,8%. 828 82 8 (82,8% IC95 IC 78,6–86,5 786865 78 6 86 5 93,1%. 931 93 (93,1% 77,2–99,2. 772992 77,2–99,2 . 77 2 99 77,2–99,2) 0,2. 02 0 (0,2 0,1–0,2. 0102 0,1–0,2 0,1–0,2) Conclusão condições 201 3 J00J9 J0 J9 J00-J 9 82,8% (82,8 IC9 78,6–86, 78686 7 93,1% (93,1 77299 77,2–99, 0,2 (0, 010 0,1–0, 20 J00J 82,8 (82, 78,6–86 7868 93,1 (93, 7729 77,2–99 0, (0 01 0,1–0 82, (82 78,6–8 786 93, (93 772 77,2–9 ( 0,1– (8 78,6– (9 77,2– 0,1 78,6 77,2 78, 77,

Abstract Background: Acute respiratory diseases are difficult to measure and contribute to a large number of ill-defined causes of death, which affects the reliability of mortality information. Objective: To verify the accuracy of the definition of the underlying cause of death for acute respiratory diseases registered in the Mortality Information System of the Federal District in 2018. Method: An accuracy study was conducted, with a minimum sample of 331 death certificates with the causes of death according to Chapter 10 (diseases of the respiratory system — J00-J99 — according to subcategories) of the International Classification of Diseases, version 10, considering the definition of the underlying cause of death by the research team as the gold standard. Sensitivity, specificity, positive and negative predictive values, and positive and negative likelihood ratios were calculated with their respective 95% confidence intervals (CIs). Results: Overall, 396 death certificates were included. High sensitivity was identified to determine acute lung diseases in the underlying cause of death (82.8%, 95%CI 78.6–86.5) and high specificity (93.1%, 95%CI 77.2–99.2). The probability of the declaration shows that negative false value was low (0.2, 95%CI 0.1–0.2). Conclusion: Death certificates due to acute respiratory diseases showed good results for accuracy and this study encourages similar studies for other conditions. Background illdefined ill defined information Objective 2018 Method conducted 33 1 J00J99 JJ J00 J99 J J00-J9 subcategories Diseases standard Sensitivity values 95 CIs. CIs . (CIs) Results Overall 39 included 82.8%, 828 82 8 (82.8% 95CI CI 78.6–86.5 786865 78 6 86 5 93.1%, 931 93 (93.1% 77.2–99.2. 772992 77.2–99.2 77 2 99 77.2–99.2) 0.2, 02 0 (0.2 0.1–0.2. 0102 0.1–0.2 0.1–0.2) Conclusion conditions 201 3 J00J9 J0 J9 J00-J 9 (CIs 82.8% (82.8 78.6–86. 78686 7 93.1% (93.1 77299 77.2–99. 0.2 (0. 010 0.1–0. 20 J00J 82.8 (82. 78.6–86 7868 93.1 (93. 7729 77.2–99 0. (0 01 0.1–0 82. (82 78.6–8 786 93. (93 772 77.2–9 ( 0.1– (8 78.6– (9 77.2– 0.1 78.6 77.2 78. 77.

RESUMO Objetivos: avaliar a contribuição de cuidadores informais para o autocuidado de pessoas com insuficiência cardíaca. Métodos: estudo transversal, realizado com 87 cuidadores, de março a outubro de 2022, na cidade João Pessoa/PB. A contribuição do cuidador foi avaliada por meio do instrumento Caregiver Contribution to Self-Care of Heart Failure Index. Escores ≥ 70 pontos indicam contribuição adequada. Os dados foram analisados por meio de estatística descritiva e correlação de Spearman. Resultados: eram do sexo feminino 81,6% da amostra. A mediana dos escores obtidos para as escalas de contribuição para o autocuidado foram: 63,3 para manutenção; 55,5 para manejo; e 66,6 para confiança. Os cuidadores nunca ou raramente recomendavam o monitoramento do peso corporal, a prática regular de exercícios físicos, o uso extra de diuréticos e a restrição de líquidos. Conclusões: os cuidadores informais apresentaram contribuição inadequada nos quesitos manutenção, manejo e confiança do autocuidado de pessoas com insuficiência cardíaca. Objetivos cardíaca Métodos transversal 8 2022 PessoaPB Pessoa PB Pessoa/PB SelfCare Self Care Index 7 adequada Spearman Resultados 816 81 6 81,6 amostra 633 63 3 63, manutenção 555 55 5 55, 666 66 66, corporal físicos líquidos Conclusões 202 81, 20 2

ABSTRACT Objectives: to evaluate the contribution of informal caregivers to the self-care of individuals with heart failure. Methods: a cross-sectional study was conducted with 87 caregivers from March to October 2022 in the city of João Pessoa/PB. The caregivers’ contribution was assessed using the Caregiver Contribution to Self-Care of Heart Failure Index instrument. Scores ≥ 70 points indicate adequate contribution. Data were analyzed using descriptive statistics and Spearman’s correlation. Results: the sample consisted of 81.6% female caregivers. Median scores obtained for the self-care contribution scales were: 63.3 for maintenance; 55.5 for management; and 66.6 for confidence. Caregivers never or rarely recommended monitoring body weight, regular physical exercise, extra use of diuretics, and fluid restriction. Conclusions: informal caregivers showed inadequate contribution in the areas of maintenance, management, and confidence in self-care of individuals with heart failure. Objectives selfcare self care failure Methods crosssectional cross sectional 8 202 PessoaPB Pessoa PB Pessoa/PB SelfCare Self Care instrument 7 Spearmans Spearman s correlation Results 816 81 6 81.6 633 63 3 63. maintenance 555 55 5 55. management 666 66 66. weight exercise diuretics restriction Conclusions 20 81. 2

RESUMEN Objetivos: evaluar la contribución de cuidadores informales para el autocuidado de personas con insuficiencia cardíaca. Métodos: estudio transversal, realizado con 87 cuidadores, de marzo a octubre de 2022, en la ciudad João Pessoa/PB. La contribución del cuidador fue evaluada mediante el instrumento Caregiver Contribution to Self-Care of Heart Failure Index. Escores ≥ 70 puntos indican contribución adecuada. Los datos fueron analizados mediante estadística descriptiva y correlación de Spearman. Resultados: son del sexo femenino 81,6% de la muestra. La mediana de los escores obtenidos para las escalas de contribución para el autocuidado fueron: 63,3 para manutención; 55,5 para manejo; y 66,6 para confianza. Los cuidadores nunca o raramente recomendaban el monitoreo del peso corporal, la práctica regular de ejercicios físicos, el uso extra de diuréticos y la restricción de líquidos. Conclusiones: los cuidadores informales presentaron contribución inadecuada en los quesitos manutención, manejo y confianza del autocuidado de personas con insuficiencia cardíaca. Objetivos cardíaca Métodos transversal 8 2022 PessoaPB Pessoa PB Pessoa/PB SelfCare Self Care Index 7 adecuada Spearman Resultados 816 81 6 81,6 muestra 633 63 3 63, manutención 555 55 5 55, 666 66 66, corporal físicos líquidos Conclusiones 202 81, 20 2

Resumo: Um dos impactos ambientais mais comuns que tem causado efeitos irreversíveis nos ecossistemas é a introdução de espécies exóticas. Além dos desastres ecológicos que podem ser provocados, como o declínio e a extinção de espécies nativas, este fenómeno pode gerar perdas económicas significativas e a possibilidade de propagação de parasitas que são transmitidos por estas espécies exóticas. Esses processos podem ser acentuados pelas mudanças climáticas, que ao longo do tempo alteram o padrão de distribuição global das espécies afetadas, gerando casos de sobreposição de nicho com espécies que compartilham nichos semelhantes. Nesse sentido, o conhecimento sobre as áreas com possível ocorrência dessas espécies pode direcionar as medidas de monitoramento e controle. Neste estudo, desenvolvemos modelos de previsão atuais e futuros para identificar áreas de adequabilidade na região Neotropical para Melanoides tuberculata (Müller, 1774) e nove espécies de moluscos nativos do continente americano, utilizando a ferramenta de modelagem de nicho ecológico. Além disso, avaliamos a sobreposição de nicho ecológico entre a espécie invasora e as espécies nativas de moluscos de água doce para verificar se os efeitos das mudanças climáticas alterariam a distribuição desses organismos. Para a elaboração dos modelos de predição, foram adotados os seguintes procedimentos metodológicos: registros de ocorrência dos moluscos em diferentes bases de dados e busca de dados ambientais para condições climáticas em cenários atuais e futuros no WorldClim 2.0 (SSP2-4.5 e SSP2-8.5). Além disso, foram realizados procedimentos de modelagem utilizando sete pacotes do software R, avaliação dos modelos utilizando a métrica True Skill Statistic (TSS), construção de mapas e quantificação e sobreposição de nicho ecológico das espécies incluídas na análise. Os resultados indicaram que várias áreas da região Neotropical são adequadas para a ocorrência de M. tuberculata nos cenários atuais. Além disso, as áreas adequadas para a sua ocorrência serão provavelmente alargadas em ambos os cenários futuros. Para as espécies nativas, houve diferenças significativas em relação às áreas de aptidão, com uma redução para algumas espécies. Testes de similaridade de nicho indicaram sobreposição significativa apenas entre M. tuberculata e o planorbídeo Biomphalaria straminea (Dunker, 1848). Verificamos que a expansão de M. tuberculata pode ter consequências negativas, incluindo a redução de espécies nativas de gastrópodes e a disseminação de trematódeos de importância médica e veterinária que este molusco pode transmitir. Resumo exóticas provocados afetadas semelhantes sentido controle estudo Müller, Müller (Müller 1774 americano disso organismos predição metodológicos 20 2 0 2. SSP24.5 SSP245 SSP SSP2 4.5 4 5 (SSP2-4. SSP28.5. SSP285 8.5 . 8 SSP2-8.5) R TSS, TSS , (TSS) análise M aptidão Dunker, Dunker (Dunker 1848. 1848 1848) negativas transmitir 177 SSP24 SSP24. 45 4. (SSP2-4 SSP28 SSP28.5 85 8. SSP2-8.5 (TSS 184 17 (SSP2- SSP28. SSP2-8. 18 1 (SSP2 SSP2-8 (SSP SSP2-

Abstract: One of the most common environmental impacts that has caused irreversible effects on ecosystems is the introduction of exotic species. In addition to the ecological disasters that can be caused, such as the decline and extinction of native species, this phenomenon can generate significant economic losses and the possibility of the spread of parasites that are transmitted by these exotic species. These processes can be accentuated by climate change, which over time alters the global distribution pattern of the affected species, generating cases of niche overlap with species that share similar niches. In this sense, the knowledge about the areas with possible occurrence these species can direct the monitoring and control measures. In this study, we developed current and future prediction models to identify areas of suitability in the Neotropics for Melanoides tuberculata (Müller, 1774) and nine species of mollusks native to the American continent using the ecological niche modeling tool. In addition, we evaluated the ecological niche overlap between the invasive species and the native species of freshwater mollusks to verify whether the effects of climate change would alter the distribution of these organisms. The following methodological procedures were adopted to prepare the forecasting models: records of occurrence of the mollusks in different databases and search of environmental data for climate conditions in current and future scenarios in WorldClim 2.0 (SSP2-4.5 and SSP2-8.5). Besides, modeling procedures using seven packages of R software, evaluation of the models using the true skill statistic (TSS) metric, construction of maps and quantification and overlapping of ecological niche of the species included in the analysis. The results indicated that several areas of the Neotropics are suitable for the occurrence of M. tuberculata in the current scenarios. Moreover, the suitable areas for its occurrence will probably be expanded in both future scenarios. For native species, there were significant differences in relation to the areas of suitability, with a reduction for some species. Niche similarity tests indicated significant overlap only between M. tuberculata and the planorbid Biomphalaria straminea (Dunker, 1848). We discuss that the expansion of M. tuberculata can have negative consequences, including the reduction of native gastropod species and the spread of trematodes of medical and veterinary importance that this mollusk can transmit. Abstract niches sense measures study Müller, Müller (Müller 1774 tool organisms 20 2 0 2. SSP24.5 SSP245 SSP SSP2 4.5 4 5 (SSP2-4. SSP28.5. SSP285 8.5 . 8 SSP2-8.5) Besides software TSS (TSS metric analysis M Moreover Dunker, Dunker (Dunker 1848. 1848 1848) consequences transmit 177 SSP24 SSP24. 45 4. (SSP2-4 SSP28 SSP28.5 85 8. SSP2-8.5 184 17 (SSP2- SSP28. SSP2-8. 18 1 (SSP2 SSP2-8 (SSP SSP2-

ABSTRACT Objective: To report nine cases of pediatric patients with Acute Lymphoid Leukemia (ALL) or Acute Myeloid Leukemia who developed severe oral mucositis (SOM) at the first week of chemotherapy. Material and Methods: The cases were selected from a sample of 105 children followed for 10 consecutive weeks. Hematological and personal data were obtained from the patient's medical records. The oral cavity was examined weekly using the modified Oral Assessment Guide. Results: More of the patients were male (55.6%), had black/brown skin (55.6%), with ALL (66.7%), and the mean age was 5.55. Two patients had values below normal for leukocytes, platelets, and creatinine over the follow-up. However, all patients showed changes in the normality of hematological data in most weeks. The most used chemotherapeutic agents were aracytin, etoposide, and methotrexate, known for their high stomatotoxic potential. Patients had 2 to 6 (mean of 4) episodes of SOM and 4 to 7 (mean of 5.5) episodes of OM. One patient at week 7, one patient at week 5, and one patient at weeks 2 and 10 did not have OM. Saliva (84 times) and lips (44 times) were the most affected items. Conclusion: The patients showed oscillations in the severity of oral mucositis and hematological parameters over the follow-up. All patients were exposed to stomatotoxic drugs during the initial phase of cancer treatment. Objective (ALL (SOM chemotherapy Methods 1 s records Guide Results 55.6%, 556 55.6% , 55 (55.6%) blackbrown black brown 66.7%, 667 66.7% 66 (66.7%) 555 5 5.55 leukocytes platelets followup. followup follow up. up follow-up However aracytin etoposide methotrexate potential 5.5 OM 84 (8 times 44 (4 items Conclusion treatment 55.6 (55.6% 66.7 (66.7% 5. 8 ( 55. (55.6 66. (66.7 (55. (66. (55 (66 (5 (6

Resumen: Objetivo: Identificar las prácticas de promoción de la lactancia materna en el contexto hospitalario brasileño. Método: Este estudio es una revisión bibliográfica integradora que utiliza las siguientes bases de datos: LILACS, BDENF, MEDLINE y PUBMED. Basado en los descriptores de Ciencias de la Salud: Breast Feeding; Hospital; Health Promotion, que se cruzarán utilizando el operador booleano AND. Resultados: En esta revisión integradora se seleccionaron 14 estudios que permitieron identificar las siguientes prácticas de promoción del parto materno en el contexto hospitalario: el contacto de la piel con la piel después del nacimiento, el tipo de parto, la asistencia enfermera y el manejo del dolor durante el proceso de amamantamiento. Conclusión: Se observó que este estudio identificó la práctica de promoción de la salud materna en el contexto hospitalario, descrita en los resultados de forma sistematizada. Esta práctica hace necesario realizar cambios dentro de los hospitales y se implantan de forma correcta.

Abstract: Objective: Identify breastfeeding promotion practices in the Brazilian hospital context. Method: This study is an integrative literature review in which the following databases were used: LILACS, BDENF, MEDLINE and PUBMED. Using the descriptors in Health Sciences: Breast Feeding; Hospital; Health Promotion, which are crossed using the Boolean operator AND. Results: Fourteen studies were selected in this integrative review, which allowed the identification of the following breastfeeding promotion practices in hospital settings: skin-to-skin contact after birth, type of delivery, nursing care, and pain management during the breastfeeding process. Conclusion: It was observed that this study identified the practice of breastfeeding promotion in the hospital context, described in the results in a systematized way. This practice needs to be changed in hospitals and be correctly implemented.

Resumo: Objetivo: Identificar práticas de promoção ao aleitamento materno no contexto hospitalar brasileiro. Método: O presente estudo trata-se de uma revisão integrativa da literatura na qual foram utilizadas as bases de dados: LILACS, BDENF, MEDLINE e PUBMED. Também foi realizado a partir dos Descritores em Ciências da Saúde: Breast Feeding; Hospital; Health Promotion, os quais foram cruzados utilizando o operador booleano AND. Resultados: Foram selecionados nesta revisão integrativa 14 estudos que permitiram a identificação das seguintes práticas de promoção ao aleitamento materno no contexto hospitalar: o contato pele a pele após o nascimento, o tipo do parto, a assistência de enfermagem e o manejo da dor durante o processo da amamentação. Conclusão: Observou-se que este estudo identificou a prática de promoção ao aleitamento materno no contexto hospitalar, descrito nos resultados de forma sistematizada. Constatamos que há a necessidade de mudanças dessas práticas dentro dos hospitais e que sejam implantadas de maneira correta.

Abstract Objective: To describe the impact of the COVID-19 pandemic on dental care provided to pediatric cancer patients assisted in a referral hospital. Material and Methods: This is an observational, retrospective study based on secondary data extracted from worksheets of dental procedures for patients aged between 0 and 19 years assisted in the pediatric oncology sector of a hospital in João Pessoa, PB, Brazil. Dental procedures performed by the interdisciplinary team of researchers from August 2018 to February 2020 (19 months prior to the pandemic) and from April 2020 to October 2021 (19 months during the pandemic) were totaled and compared. A descriptive analysis of the data was performed. Results: There was a reduction of 80.2% in dental interventions implemented in the sector during the pandemic, with the number of procedures decreasing from 6,210 (the period before the pandemic) to 1,229 (during the pandemic). Most procedures in both periods were performed for patients assisted in beds, for whom there was a reduction of care provided for 81.2% from 5,275 to 994 procedures. Dental procedures in the outpatient clinic decreased by 74.9%, from 935 to 235. Conclusion: The COVID-19 pandemic negatively impacted dental care provided to pediatric oncology patients by restricting dental procedures to emergency demands, compromising performance prevention and health promotion actions.

Metabolomics, together with analytical methods and chemometric tools, point to new paths for selecting species that are resistant to pests and diseases. In this work, the forage palm species' metabolomic profile was investigated, and the relation between the chemical composition and resistance to Dactylopius opuntiae (carmine cochineal). The study was performed in cladodes of different non-susceptible cultivars (Nopalea cochenillifera (L.) Salm-Dyck, Opuntia stricta (Haw.), Nopalea cochenillifera and susceptible cultivar (Opuntia ficus-indica (L.) Mill.)). Metabolic profile showed 28 metabolites detected in the four species. From these total, 18 metabolites were annotated using UPLC-QTOF-MSE (ultra-performance liquid chromatography coupled with an electrospray ionization quadrupole time-of-flight mass spectrometry operating in MSE mode). By comparing the chemical profiles of non-susceptible and susceptible species through the application of chemometric tools, it was possible to obtain biomarkers (quercetin-3-O-2',6'-dirhamnosylglucoside, quercetin rhamnosyl dihexoside, and isorhamnetin-3-sophoroside-7-rhamnoside) that may be associated with resistance to carmine cochineal. Metabolomics based on UPLC-QTOF-MSE and chemometric allowed to establish the biomarkers knowledge of the resistance present in forage palm species. These results contribute to developing the initial understanding of flavonoids' role in the defense mechanisms of cactaceans and can be useful for application in breeding programs; it can increase the chances of success in creating new varieties of plants not susceptible to carmine cochineal.

RESUMO Objetivo: Apresentar as diretrizes de estimulação sensório-motora para recém-nascidos e lactentes em unidade de terapia intensiva., Métodos: Trata-se de um método de delineamento misto com revisão sistemática da literatura e recomendações com base na evidência científica e opiniões de fisioterapeutas especialistas em fisioterapia neonatal de estudos publicados entre 2010 e 2018 nas bases de dados MEDLINE® e Cochrane, que incluiu recém-nascidos (pré-termo e a termo) e lactentes (entre 28 dias e 6 meses de idade) admitidos à unidade de terapia intensiva e submetidos a métodos de estimulação sensório-motora. Os estudos encontrados foram classificados segundo o escore GRADE por cinco fisioterapeutas em diferentes regiões do país e apresentados em oito congressos científicos para discussão das diretrizes de práticas clínicas., Resultados: Foram incluídos 89 artigos para construir as diretrizes de práticas clínicas. Estimulação auditiva, gustatória e contato pele a pele se destacaram por melhorar os sinais vitais, e a massagem terapêutica, assim como a estimulação multimodal tátil-cinestésica por melhorar o peso ou a sucção., Conclusão: Embora todas a modalidades tenham boas avaliações para controle da dor ou do estresse, é recomendado que os procedimentos de estimulação sensório-motora sejam adaptados às necessidades específicas da criança, e as intervenções sejam realizadas por profissionais experientes.

Abstract Objective: To present guidelines on sensory motor stimulation for newborns and infants in the intensive care unit. Methods: We employed a mixed methods design with a systematic review of the literature and recommendations based on scientific evidence and the opinions of physiotherapists with neonatal expertise. The research included studies published between 2010 and 2018 in the MEDLINE® and Cochrane databases that included newborns (preterm and term) and infants (between 28 days and 6 months of age) hospitalized in the intensive care unit and submitted to sensory motor stimulation methods. The studies found were classified according to the GRADE score by five physiotherapists in different regions of Brazil and presented at eight Scientific Congresses held to discuss the clinical practice guidelines. Results: We included 89 articles to construct the clinical practice guidelines. Auditory, gustatory and skin-to-skin stimulation stand out for enhancing vital signs, and tactile-kinesthetic massage and multisensory stimulation stand out for improving weight or sucking. Conclusion: Although all modalities have good ratings for pain or stress control, it is recommended that sensory motor stimulation procedures be tailored to the infant’s specific needs and that interventions and be carried out by expert professionals.

ABSTRACT Objective: To evaluate the antibacterial effect and the solubility of experimental root canal filling pastes containing the phytoconstituents terpineol and cinnamaldehyde. Material and Methods: Minimum Inhibitory Concentration (MIC) of each phytoconstituent was determined against Enterococcus faecalis. Five groups of antibiotic pastes based on zinc oxide were obtained by mixing: only terpineol, only cinnamaldehyde, terpineol and cinnamaldehyde combined, chlorhexidine (antibiotic control), and CTZ paste (control paste). Antibacterial activity was analyzed through direct contact test within 24 and 72 hours. Solubility was evaluated by spectrophotometry within 48 and 144 hours. Antibacterial activity data were analyzed descriptively, and solubility data was analyzed using ANOVA and Tukey tests (p<0.05). Results: The MIC obtained for terpineol and cinnamaldehyde were, respectively, 2000 µg/mL and 500 µg/mL. After 24h, only the terpineol paste did not inhibit E. faecalis growth. After 72h, all groups inhibited E. faecalis growth. After 48h, the highest solubility was verified in the terpineol paste (p<0.05), and no differences were detected among other groups (p>0.05). After and 144h, highest solubility was observed in the terpineol paste (p<0.05), followed by the CTZ paste (p<0.05). No differences were detected for cinnamaldehyde, terpineol+cinnamaldehyde and chlorhexidine pastes (p>0.05). Conclusion: Pastes containing cinnamaldehyde or terpineol+cinnamaldehyde showed antibacterial activity against E. faecalis similar to CTZ paste, with lower solubility.

Abstract This study aimed to analyze the influence of socioeconomic factors on the frequency of diagnoses of oral mucosal changes and the number of hospitalized patients with oral and oropharyngeal cancer in Brazil. This cross-sectional study analyzed data from all Brazilian cities in the period 2011–2017. The frequency of diagnoses of oral mucosal changes and the number of hospitalized patients of oral and oropharyngeal cancer in Brazil were extracted from the Primary Care Information System (SIAB) and Brazilian National Cancer Institute (INCA) databases. The socioeconomic factors evaluated were the Gini coefficient of inequality, municipal Human Development Index (MHDI), inadequate basic sanitation rate, employment rate, illiteracy rate and expected years of schooling. Associated factors were examined using bivariate Spearman’s correlations and multivariate Poisson regressions, and statistically significant (p < 0.05) correlations between study variables and regression coefficients were obtained. A higher frequency of diagnoses of mucosal changes was observed in cities with a higher Gini coefficient (B = 11.614; p < 0.001), higher MHDI (B = 11.298; p < 0.001), and higher number of hospitalized patients with oral and oropharyngeal cancer (B = 0.001, p < 0.002). Cities with higher Gini coefficients (B = 8.159, p < 0.001), higher inadequate basic sanitation rates (B = 0.09, p = 0.001), lower expected years of schooling (B = -0.718, p < 0.001), and higher illiteracy rates (B = 0.191, p < 0.001) had a higher frequency of hospitalized patients with oral and oropharyngeal cancer. In conclusion, more developed cities showed a higher frequency of diagnoses of mucosal changes. Greater inequality and worse socioeconomic conditions are associated with a higher frequency of hospitalized patients with oral and oropharyngeal cancer in Brazil.

RESUMO Objetivos: construir e analisar a validade de conteúdo de um instrumento para avaliar a intenção comportamental de indivíduos com hipertensão de tomar comprimidos anti-hipertensivos. Métodos: estudo metodológico fundamentado na teoria do comportamento planejado, desenvolvido em três etapas: elaboração do instrumento, validação de conteúdo e pré-teste com o público-alvo. O conteúdo foi validado por seis especialistas. Aplicou-se o Índice de Validade de Conteúdo. Resultados: participaram cinco enfermeiros e um psicólogo, com experiências em hipertensão arterial sistêmica e/ou teoria do comportamento planejado. A primeira versão do instrumento continha 40 itens. Após análise, originou-se a segunda versão, com 36 itens. Obteve-se concordância de 100% para abrangência dos constructos. O pré-teste evidenciou clareza e compreensão dos itens pelo públicoalvo. Conclusões: o instrumento configura-se um produto tecnológico confiável e inovador para utilização em populações com hipertensão arterial sistêmica e crenças semelhantes às identificadas no grupo pesquisado.

ABSTRACT Objectives: to build and analyze the validity of an instrument to assess the behavioral intention of individuals with hypertension to take antihypertensive pills. Methods: methodological study based on the theory of planned behavior, developed in three stages: preparation of the instrument, validation of content and pre-test with the target audience. The content has been validated by six experts. The Content Validity Index was applied. Results: five nurses and one psychologist participated, with experiences in systemic arterial hypertension and/or planned behavior theory. The first version of the instrument contained 40 items. After analysis, the second version originated, with 36 items. 100% agreement was obtained for the scope of the constructions. The pre-test showed clarity and understanding of the items by the target audience. Conclusions: the instrument is a reliable and innovative technological product for use in populations with systemic arterial hypertension and beliefs similar to those identified in the surveyed group.

RESUMEN Objetivos: construir y analizar la validez de contenido de un instrumento para evaluar la intención del comportamiento de individuos hipertensos de tomar comprimidos antihipertensivos. Métodos: estudio metodológico fundamentado en la teoría del comportamiento planeado, desarrollado en tres etapas: elaboración del instrumento, validez de contenido y pretest con el público objetivo. El contenido ha validado por seis especialistas. Se aplicó el Índice de Validez de Contenido. Resultados: participaron cinco enfermeros y un psicólogo, con experiencias en hipertensión arterial sistémica y/o teoría del comportamiento planeado. La primera versión del instrumento contenía 40 ítems. Después del análisis, se originó la segunda, con 36 ítems. Se obtuvo concordancia de 100% para inclusión de los constructos. El pretest evidenció claridad y comprensión de los ítems por el público objetivo. Conclusiones: el instrumento se configura un producto tecnológico confiable e innovador para utilización en poblaciones con hipertensión arterial sistémica y creencias semejantes a las identificadas en el equipo investigado.

RESUMEN Objetivo: identificar los predictores psicosociales que influyen la intención comportamental de tomar los antihipertensivos orales. Materiales y métodos: estudio transversal, fundamentado en la teoría de la conducta planeada. Se aplicó un cuestionario construido y validado a 220 individuos con hipertensión arterial sistémica en seguimiento ambulatorio en un hospital público. Se emplearon las pruebas de Cui-cuadrado y exacto de Fisher, correlación de Spearman y regresión logística múltiple para analizar los datos. Resultados: los participantes presentaron alta intención de tomar los antihipertensivos. Las creencias comportamentales (ß = 0,0432; p = 0,0364), la norma subjetiva (ß = -1,5708; p < 0,01) y el control comportamental percibido (ß = 2,2809; p = 0,0028) explicaron la intención comportamental en el 33 %. Conclusiones: creencias comportamentales, norma subjetiva y control comportamental percibido son predictores psicosociales significativos de la tomada de los antihipertensivos y deben valorarse, de forma individual y conjunta, en las acciones de salud hacia esta población.

ABSTRACT Objective: To identify the psychosocial predictors that influence the behavioral intention to take oral antihypertensive drugs. Materials and methods: A cross-sectional study, based on the theory of planned behavior. A questionnaire constructed and validated was applied to 220 individuals with systemic arterial hypertension in outpatient follow-up at a public hospital. The chi-square and Fisher's exact tests, Spearman's correlation and multiple logistic regression were used for data analysis. Results: The participants presented a high intention of taking antihypertensive drugs. The behavioral beliefs (ß = 0.0432; p = 0.0364), subjective norm (ß = -1.5708; p < 0.01) and perceived behavioral control (ß = 2.2809; p = 0.0028) explained the behavioral intention in 33 %. Conclusions: The behavioral beliefs, the subjective norm, and the perceived behavioral control are significant psychosocial predictors of taking antihypertensive drugs and must be valued, individually and jointly, in the health actions targeted at this population.

RESUMO Objetivo: identificar os preditores psicossociais que influenciam a intenção comportamental de tomar os anti-hipertensivos orais. Materiais e métodos: estudo transversal, fundamentado na teoria do comportamento planejado. Aplicou-se um questionário construído e validado a 220 indivíduos com hipertensão arterial sistêmica em acompanhamento ambulatorial em um hospital público. Utilizaram-se os testes qui-quadrado e exato de Fisher, correlação de Spearman e regressão logística múltipla para as análises dos dados. Resultados: os participantes apresentaram alta intenção de tomar os anti-hipertensivos. As crenças comportamentais (ß = 0,0432; p = 0,0364), a norma subjetiva (ß = -1,5708; p < 0,01) e o controle comportamental percebido (ß = 2,2809; p = 0,0028) explicaram a intenção comportamental em 33 %. Conclusões: crenças comportamentais, norma subjetiva e controle comportamental percebido são preditores psicossociais significativos da tomada dos anti-hipertensivos e devem ser valorizados, de forma individual e conjunta, nas ações de saúde direcionadas a essa população.