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1.
Serological evidence of Leptospiraspp. infection in livestock from indigenous villages in the Caatinga biome, Brazil Leptospiraspp biome
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Oliveira, Matheus Carvalho Freire de
; Santos, José Felipe Napoleão
; Medeiros, Avana Maria Lucena Alencar de
; Castro, Vanessa
; Bezerra, Camila de Sousa
; Alves, Clebert José
; Azevedo, Sérgio Santos de
; Santos, Carolina de Sousa Américo Batista
.
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ABSTRACT: Leptospirosis, a disease of significant economic impact on livestock and public health concern, may exhibit unique epidemiological characteristics in indigenous villages, particularly those located within semiarid climates such as the Caatinga biome in Brazil. This environment often presents conditions unfavorable for leptospire survival. This study conducted serological diagnoses of livestock in indigenous villages within the Caatinga biome, Northeastern Brazil. The survey was carried out in the Mãe Maria and Santa Helena indigenous villages, home to the Xukuru de Cimbres tribe, in the county of Pesqueira, Pernambuco State, Brazil, within the Caatinga biome. Blood samples were collected from cattle (n = 42), goats (n = 41), and sheep (n = 19). Out of the 102 samples tested, 73 (71.6%; 95% CI = 62.8% - 80.3%) were seroreactive (cut-off ≥ 100). The seropositivity rates for cattle, goats, and sheep were 54.8%, 80.5%, and 89.5%, respectively. A statistically significant difference was observed in the proportion of seropositive animals between cattle and goats and cattle and sheep (P < 0.05). Icterohaemorrhagiae was identified as the most probable serogroup across all animal species. The study revealed that livestock in indigenous villages within the Caatinga biome are frequently exposed to leptospires. This finding underscores the importance of a One Health approach, emphasizing the need for comprehensive studies in areas where large human and animal populations coexist. Such studies are crucial for investigating zoonotic infections and for planning and implementing control measures against livestock-associated leptospirosis. ABSTRACT Leptospirosis concern Brazil survival tribe Pesqueira State n 42, 42 , 42) 41, 41 41) 19. 19 . 19) 10 tested 7 71.6% 716 71 6 (71.6% 95 628 62 8 62.8 80.3% 803 80 3 cutoff cut off 100. 100 100) 548 54 54.8% 805 5 80.5% 895 89 89.5% respectively P 0.05. 005 0.05 0 05 0.05) species leptospires approach coexist livestockassociated associated leptospirosis 4 1 71.6 (71.6 9 62. 80.3 54.8 80.5 89.5 00 0.0 71. (71. 80. 54. 89. 0. (71 (7 (
RESUMO: A leptospirose causa perdas econômicas na pecuária e é um problema de saúde pública, sendo possível que existam peculiaridades na epidemiologia dessa doença em aldeias indígenas, principalmente naquelas de áreas de clima semiárido, como o bioma Caatinga no Nordeste do Brasil, onde o ambiente é frequentemente adverso à sobrevivência de leptospiras. Assim, o objetivo deste estudo foi realizar o diagnóstico sorológico em rebanhos de aldeias indígenas no bioma Caatinga. A pesquisa foi realizada nas aldeias indígenas Mãe Maria e Santa Helena, tribo Xukuru de Cimbres, município de Pesqueira, estado de Pernambuco, Brasil, dentro do bioma Caatinga. Amostras de sangue foram colhidas de bovinos (n = 42), caprinos (n = 41) e ovinos (n = 19). No geral, das 102 amostras testadas 73 (71,6%; IC 95% = 62,8% - 80,3%) foram sororreativas (ponto de corte ≥ 100). Para bovinos, caprinos e ovinos as taxas de soropositividade foram de 54,8%, 80,5% e 89,5%, respectivamente. Houve diferença estatística na proporção de animais soropositivos entre bovinos e caprinos e bovinos e ovinos (P < 0,05). Icterohaemorrhagiae foi o sorogrupo mais provável em todas as espécies animais. O estudo mostra que animais de produção de aldeias indígenas são comumente expostos a leptospiras no bioma Caatinga, o que constitui uma preocupação do ponto de vista de Saúde Única e demonstra a importância de estudos amplos em que coexistem grandes números de humanos e animais na investigação de infecções zoonóticas e no planejamento e implementação de medidas de controle da leptospirose associada a animais de produção. RESUMO pública semiárido Brasil Assim Helena Cimbres Pesqueira Pernambuco n 42, 42 , 42) 41 19. 19 . 19) geral 10 7 71,6% 716 71 6 (71,6% 95 628 62 8 62,8 80,3% 803 80 3 100. 100 100) 548 54 54,8% 805 5 80,5 895 89 89,5% respectivamente P 0,05. 005 0,05 0 05 0,05) 4 1 71,6 (71,6 9 62, 80,3 54,8 80, 89,5 00 0,0 71, (71, 54, 89, 0, (71 (7 (
2.
Criação e desenvolvimento de grupos de apoio para o autocuidado em hanseníase em um estado do Nordeste brasileiro
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Nascimento, Raphaela Delmondes do
; Sousa, Islândia Maria Carvalho de
; Melo, Camila Pimentel Lopes de
; Santos, Danielle Christine Moura dos
.
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Abstract Objective To understand the creation and development of support groups for leprosy in a state in the northeast of Brazil. Methods Qualitative study conducted with three groups in northeast Brazil, from February to December 2019. Data collection included interviews, participant observation, and document analysis. Data were analyzed using the content analysis technique, considering preestablished topics: implementation, organization, and continuity of the groups. Results The most common reasons presented by the groups for the implementation were the needs to expand care and optimize working time. The stigma and service organization issues were obstacles to implementation. The most relevant factor for the continuity of groups was the involvement of the coordinators in the activities. Support from external actors, such NGOs and universities, was relevant to implementation and continuity. Final considerations Similarities and differences among groups are related to participants, actions to foster the groups, health policy support, and interference from external actors. Support groups for leprosy self-care are spaces that strengthen the practice of care. This study contributed to implement or reorganize self-care support groups. Brazil 2019 interviews observation technique topics time activities actors universities participants selfcare self 201 20 2
Resumo Objetivo Compreender a criação e desenvolvimento de grupos de apoio para o autocuidado em hanseníase em um estado do Nordeste brasileiro. Métodos Estudo qualitativo realizado em três grupos no Nordeste do Brasil, entre fevereiro e dezembro de 2019. A coleta de dados englobou entrevistas, observação participante e análise documental. Os dados foram analisados segundo a técnica de análise de conteúdo a partir dos temas preestabelecidos: implantação, organização e continuidade dos grupos. Resultados A implantação dos grupos apresentou como motivos comuns a necessidade de ampliação dos cuidados, e de otimização do tempo de trabalho. O estigma e questões da organização dos serviços foram obstáculos para a implantação. O fator mais relevante para a continuidade dos grupos foi o envolvimento dos coordenadores nas atividades. O apoio de atores externos como ONG e universidades foram relevantes para a implantação e continuidade. Considerações finais As similaridades e diferenças dos grupos relacionam-se aos participantes, à indução e apoio da política de saúde e às interferências de atores externos. Grupos de apoio para o autocuidado em hanseníase são espaços que potencializam a prática de cuidado. O estudo contribui com a implantação ou reorganização de grupos de apoio ao autocuidado. brasileiro Brasil 2019 entrevistas documental preestabelecidos cuidados trabalho atividades relacionamse relacionam se participantes cuidado 201 20 2
3.
Dimensions of the COVID-19 pandemic: prevalence of common mental disorders in "invisible" health workers and their association with occupational stressors
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Maturino, Manuela Matos
; Sousa, Camila Carvalho de
; Moraes, Lusicleide Galindo da Silva
; Souza, Danyella Santana
; Freitas, Maria Yaná Guimarães Silva
; Araújo, Tânia Maria de
.
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ABSTRACT Objective: To evaluate the association between occupational stressors and common mental disorders (CMD) among "invisible" health workers in the context of the COVID-19 pandemic. Method: Cross-sectional study including a probabilistic sample of 1,014 health workers from three municipalities in Bahia. CMDs were assessed using the SRQ-20. The Effort-Reward Imbalance (ERI) scale and the Demand-Control Model assessed occupational stressors. Descriptive, bivariate, and multiple analysis to evaluate the association between the variables of interest. Results: The global prevalence of CMD was 39.9%; it was higher among CHA/EDCA (47.2%), followed by management and surveillance staff (38.6%), technicians (35.4%), and support/maintenance/cleaning staff (29.9%). The association between occupational stressors and CMD varied among occupations: 1. Excessive work commitment (EWC), effort-reward imbalance (ERI), and psychological demand were associated with CMD among support/maintenance/cleaning workers; 2. EWC and ERI were associated with CMD among CHA/EDCA; 3. EWC, ERI, and low control over work were associated with CMD among technicians; 4. Among management and surveillance workers, only ERI remained associated with CMD. Conclusions: Occupational stressors played a relevant role in mental illness, with variation between occupational strata, demanding attention, monitoring, and control.
RESUMO Objetivo: Avaliar associação entre estressores ocupacionais e transtornos mentais comuns (TMC) entre trabalhadores e trabalhadoras "invisíbilizados" da saúde, no contexto da pandemia de COVID-19. Métodos: Estudo transversal com amostra probabilística de 1.014 trabalhadores(as) da saúde de três municípios baianos. Os TMC foram avaliados pelo SRQ-20. A escala Desequilíbrio Esforço-Recompensa (DER) e o Modelo Demanda-Controle avaliaram os estressores ocupacionais. Análise descritiva, bivariada e múltipla avaliaram associação entre as variáveis de interesse. Resultados: A prevalência global de TMC foi de 39,9%, sendo mais elevada entre os Agentes Comunitários de Saúde/Agente de Combate às Endemias — ACS/ACE (47,2%), seguidos pelo pessoal da gestão e vigilância (38,6%), técnicos (35,4%) e pessoal de apoio/conservação/limpeza (29,9%). A associação entre estressores ocupacionais e TMC variou entre as ocupações: 1. Comprometimento excessivo com o trabalho (CET), DER e demandas psicológicas associaram-se aos TMC entre trabalhadores de apoio/conservação/limpeza; 2. CET e DER estavam associadas aos TMC entre ACS/ACE; 3. CET, DER e baixo controle sobre o trabalho associaram-se aos TMC entre os técnicos; 4. Entre trabalhadores de gestão e vigilância, apenas o DER estava associado aos TMC. Conclusões: Estressores ocupacionais tiveram papel relevante no adoecimento mental, com variação entre os estratos de ocupação, demandando atenção, acompanhamento e controle.
4.
Dimensions of the COVID-19 pandemic: prevalence of common mental disorders in "invisible" health workers and their association with occupational stressors COVID19 COVID 19 COVID-1 pandemic invisible "invisible COVID1 1 COVID-
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Maturino, Manuela Matos
; Sousa, Camila Carvalho de
; Moraes, Lusicleide Galindo da Silva
; Souza, Danyella Santana
; Freitas, Maria Yaná Guimarães Silva
; Araújo, Tânia Maria de
.
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RESUMO Objetivo: Avaliar associação entre estressores ocupacionais e transtornos mentais comuns (TMC) entre trabalhadores e trabalhadoras "invisíbilizados" da saúde, no contexto da pandemia de COVID-19. Métodos: Estudo transversal com amostra probabilística de 1.014 trabalhadores(as) da saúde de três municípios baianos. Os TMC foram avaliados pelo SRQ-20. A escala Desequilíbrio Esforço-Recompensa (DER) e o Modelo Demanda-Controle avaliaram os estressores ocupacionais. Análise descritiva, bivariada e múltipla avaliaram associação entre as variáveis de interesse. Resultados: A prevalência global de TMC foi de 39,9%, sendo mais elevada entre os Agentes Comunitários de Saúde/Agente de Combate às Endemias — ACS/ACE (47,2%), seguidos pelo pessoal da gestão e vigilância (38,6%), técnicos (35,4%) e pessoal de apoio/conservação/limpeza (29,9%). A associação entre estressores ocupacionais e TMC variou entre as ocupações: 1. Comprometimento excessivo com o trabalho (CET), DER e demandas psicológicas associaram-se aos TMC entre trabalhadores de apoio/conservação/limpeza; 2. CET e DER estavam associadas aos TMC entre ACS/ACE; 3. CET, DER e baixo controle sobre o trabalho associaram-se aos TMC entre os técnicos; 4. Entre trabalhadores de gestão e vigilância, apenas o DER estava associado aos TMC. Conclusões: Estressores ocupacionais tiveram papel relevante no adoecimento mental, com variação entre os estratos de ocupação, demandando atenção, acompanhamento e controle. Objetivo (TMC invisíbilizados "invisíbilizados COVID19. COVID19 COVID 19. 19 COVID-19 Métodos 1014 1 014 1.01 trabalhadoresas trabalhadores(as baianos SRQ20. SRQ20 SRQ 20. 20 SRQ-20 EsforçoRecompensa Esforço Recompensa (DER DemandaControle Demanda Controle descritiva interesse Resultados 399 39 9 39,9% SaúdeAgente Saúde Agente ACSACE ACS ACE 47,2%, 472 47,2% , 47 2 (47,2%) 38,6%, 386 38,6% 38 6 (38,6%) 35,4% 354 35 4 (35,4% apoioconservaçãolimpeza apoio conservação limpeza 29,9%. 299 29,9% . 29 (29,9%) ocupações (CET) associaramse associaram se 3 Conclusões mental ocupação atenção COVID1 COVID-1 101 01 1.0 SRQ2 SRQ-2 39,9 47,2 (47,2% 38,6 (38,6% 35,4 (35,4 29,9 (29,9% (CET COVID- 10 0 SRQ- 39, 47, (47,2 38, (38,6 35, (35, 29, (29,9 (47, (38, (35 (29, (47 (38 (3 (29 (4 ( (2
ABSTRACT Objective: To evaluate the association between occupational stressors and common mental disorders (CMD) among "invisible" health workers in the context of the COVID-19 pandemic. Method: Cross-sectional study including a probabilistic sample of 1,014 health workers from three municipalities in Bahia. CMDs were assessed using the SRQ-20. The Effort-Reward Imbalance (ERI) scale and the Demand-Control Model assessed occupational stressors. Descriptive, bivariate, and multiple analysis to evaluate the association between the variables of interest. Results: The global prevalence of CMD was 39.9%; it was higher among CHA/EDCA (47.2%), followed by management and surveillance staff (38.6%), technicians (35.4%), and support/maintenance/cleaning staff (29.9%). The association between occupational stressors and CMD varied among occupations: 1. Excessive work commitment (EWC), effort-reward imbalance (ERI), and psychological demand were associated with CMD among support/maintenance/cleaning workers; 2. EWC and ERI were associated with CMD among CHA/EDCA; 3. EWC, ERI, and low control over work were associated with CMD among technicians; 4. Among management and surveillance workers, only ERI remained associated with CMD. Conclusions: Occupational stressors played a relevant role in mental illness, with variation between occupational strata, demanding attention, monitoring, and control. Objective (CMD invisible "invisible COVID19 COVID 19 COVID-1 pandemic Method Crosssectional Cross sectional 1014 1 014 1,01 Bahia SRQ20. SRQ20 SRQ 20. 20 SRQ-20 EffortReward Effort Reward (ERI DemandControl Demand Control Descriptive bivariate interest Results 39.9% 399 39 9 CHAEDCA CHA EDCA 47.2%, 472 47.2% , 47 2 (47.2%) 38.6%, 386 38.6% 38 6 (38.6%) 35.4%, 354 35.4% 35 4 (35.4%) supportmaintenancecleaning support maintenance cleaning 29.9%. 299 29.9% . 29 (29.9%) occupations (EWC) effortreward effort reward 3 Conclusions illness strata attention monitoring COVID1 COVID- 101 01 1,0 SRQ2 SRQ-2 39.9 47.2 (47.2% 38.6 (38.6% 35.4 (35.4% 29.9 (29.9% (EWC 10 0 1, SRQ- 39. 47. (47.2 38. (38.6 35. (35.4 29. (29.9 (47. (38. (35. (29. (47 (38 (35 (29 (4 (3 (2 (
5.
Efeitos combinados de gênero, raça e estressores ocupacionais na saúde mental gênero
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Abstract Objective: analyze the isolated and combined effects of gender, race, and occupational stressors on the mental health of healthcare workers. Methods: cross-sectional study with a random sample of health workers in Bahia, Brazil. The primary exposure variables were gender, race, and occupational stressors, assessed using the Effort-Reward Imbalance (ERI) scale. The Self-Reporting Questionnaire (SRQ-20) measured common mental disorders (CMD), the outcome variable. The interaction measures were verified based on the additivity criterion by calculating the excess prevalence, excess prevalence ratio, and relative difference. Results: 3,343 workers participated, 77.9% were female. CMD prevalence was 21.7% higher among women, Black people, and those exposed to work stressors. Among Black women in a situation of ERI, the prevalence of CMD was three times higher compared with white men in a situation of balance (reference group). Discussion: black women workers accumulate social disadvantages and are more susceptible to occupations that require more significant effort and less reward. CMD prevalence was higher at the intersection of exposures. Combined effect of the factors exceeded the sum of the isolated effects, demonstrating an interaction between gender, race, and occupational stressors. Objective gender race Methods crosssectional cross sectional Bahia Brazil EffortReward Effort Reward ERI (ERI scale SelfReporting Self Reporting SRQ20 SRQ 20 (SRQ-20 CMD, , (CMD) variable ratio difference Results 3343 3 343 3,34 participated 779 77 9 77.9 female 217 21 7 21.7 people reference group. group . group) Discussion reward exposures SRQ2 2 (SRQ-2 (CMD 334 34 3,3 77. 21. (SRQ- 33 3, (SRQ
Resumo Objetivo: analisar os efeitos isolados e combinados do gênero, da raça e dos estressores ocupacionais sobre a saúde mental de trabalhadores e trabalhadoras da saúde. Métodos: estudo transversal com amostra aleatória de trabalhadores(as) da saúde da Bahia, Brasil. As variáveis de exposição principais foram: gênero, raça e estressores ocupacionais, avaliados por meio da escala de Desequilíbrio Esforço-Recompensa (DER). O Self-Reporting Questionnaire (SRQ-20) mensurou os transtornos mentais comuns (TMC), variável desfecho. As medidas de interação foram verificadas com base no critério da aditividade, pelo cálculo do excesso de prevalência, excesso de razão de prevalência e diferença relativa. Resultados: participaram 3.343 trabalhadores, 77,9% do sexo feminino. A prevalência de TMC foi 21,7% maior entre mulheres, negros e pessoas em situações de exposição aos estressores laborais. Entre as mulheres negras em situação de DER, a prevalência de TMC foi três vezes maior em relação aos homens brancos em situação de equilíbrio (grupo de referência). Discussão: trabalhadoras negras acumulam desvantagens sociais e estão mais suscetíveis a ocupações de maior esforço e menor recompensa. A prevalência de TMC foi superior na intersecção das exposições. O efeito combinado dos fatores excedeu a soma dos efeitos isolados, demonstrando interação entre gênero, raça e estressores ocupacionais. Objetivo gênero Métodos trabalhadoresas trabalhadores(as Bahia Brasil EsforçoRecompensa Esforço Recompensa DER. DER . (DER) SelfReporting Self Reporting SRQ20 SRQ 20 (SRQ-20 TMC, , (TMC) desfecho aditividade relativa Resultados 3343 3 343 3.34 779 77 9 77,9 feminino 217 21 7 21,7 laborais grupo referência. referência referência) Discussão recompensa exposições (DER SRQ2 2 (SRQ-2 (TMC 334 34 3.3 77, 21, (SRQ- 33 3. (SRQ
6.
Criação e desenvolvimento de grupos de apoio para o autocuidado em hanseníase em um estado do Nordeste brasileiro
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Nascimento, Raphaela Delmondes do
; Sousa, Islândia Maria Carvalho de
; Melo, Camila Pimentel Lopes de
; Santos, Danielle Christine Moura dos
.
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Resumo Objetivo Compreender a criação e desenvolvimento de grupos de apoio para o autocuidado em hanseníase em um estado do Nordeste brasileiro. Métodos Estudo qualitativo realizado em três grupos no Nordeste do Brasil, entre fevereiro e dezembro de 2019. A coleta de dados englobou entrevistas, observação participante e análise documental. Os dados foram analisados segundo a técnica de análise de conteúdo a partir dos temas preestabelecidos: implantação, organização e continuidade dos grupos. Resultados A implantação dos grupos apresentou como motivos comuns a necessidade de ampliação dos cuidados, e de otimização do tempo de trabalho. O estigma e questões da organização dos serviços foram obstáculos para a implantação. O fator mais relevante para a continuidade dos grupos foi o envolvimento dos coordenadores nas atividades. O apoio de atores externos como ONG e universidades foram relevantes para a implantação e continuidade. Considerações finais As similaridades e diferenças dos grupos relacionam-se aos participantes, à indução e apoio da política de saúde e às interferências de atores externos. Grupos de apoio para o autocuidado em hanseníase são espaços que potencializam a prática de cuidado. O estudo contribui com a implantação ou reorganização de grupos de apoio ao autocuidado.
Abstract Objective To understand the creation and development of support groups for leprosy in a state in the northeast of Brazil. Methods Qualitative study conducted with three groups in northeast Brazil, from February to December 2019. Data collection included interviews, participant observation, and document analysis. Data were analyzed using the content analysis technique, considering preestablished topics: implementation, organization, and continuity of the groups. Results The most common reasons presented by the groups for the implementation were the needs to expand care and optimize working time. The stigma and service organization issues were obstacles to implementation. The most relevant factor for the continuity of groups was the involvement of the coordinators in the activities. Support from external actors, such NGOs and universities, was relevant to implementation and continuity. Final considerations Similarities and differences among groups are related to participants, actions to foster the groups, health policy support, and interference from external actors. Support groups for leprosy self-care are spaces that strengthen the practice of care. This study contributed to implement or reorganize self-care support groups.
7.
Brazilian consensus recommendations on the diagnosis and treatment of autoimmune encephalitis in the adult and pediatric populations
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Dutra, Lívia Almeida
; Silva, Pedro Victor de Castro
; Ferreira, João Henrique Fregadolli
; Marques, Alexandre Coelho
; Toso, Fabio Fieni
; Vasconcelos, Claudia Cristina Ferreira
; Brum, Doralina Guimarães
; Pereira, Samira Luisa dos Apóstolos
; Adoni, Tarso
; Rocha, Leticia Januzi de Almeida
; Sampaio, Leticia Pereira de Brito
; Sousa, Nise Alessandra de Carvalho
; Paolilo, Renata Barbosa
; Pizzol, Angélica Dal
; Costa, Bruna Klein da
; Disserol, Caio César Diniz
; Pupe, Camila
; Valle, Daniel Almeida do
; Diniz, Denise Sisterolli
; Abrantes, Fabiano Ferreira de
; Schmidt, Felipe da Rocha
; Cendes, Fernando
; Oliveira, Francisco Tomaz Meneses de
; Martins, Gabriela Joca
; Silva, Guilherme Diogo
; Lin, Katia
; Pinto, Lécio Figueira
; Santos, Mara Lúcia Schimtz Ferreira
; Gonçalves, Marcus Vinícius Magno
; Krueger, Mariana Braatz
; Haziot, Michel Elyas Jung
; Barsottini, Orlando Graziani Povoas
; Nascimento, Osvaldo José Moreira do
; Nóbrega, Paulo Ribeiro
; Proveti, Priscilla Mara
; Castilhos, Raphael Machado do
; Daccach, Vanessa
; Glehn, Felipe von
.
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Abstract Background Autoimmune encephalitis (AIE) is a group of inflammatory diseases characterized by the presence of antibodies against neuronal and glial antigens, leading to subacute psychiatric symptoms, memory complaints, and movement disorders. The patients are predominantly young, and delays in treatment are associated with worse prognosis. Objective With the support of the Brazilian Academy of Neurology (Academia Brasileira de Neurologia, ABN) and the Brazilian Society of Child Neurology (Sociedade Brasileira de Neurologia Infantil, SBNI), a consensus on the diagnosis and treatment of AIE in Brazil was developed using the Delphi method. Methods A total of 25 panelists, including adult and child neurologists, participated in the study. Results The panelists agreed that patients fulfilling criteria for possible AIE should be screened for antineuronal antibodies in the serum and cerebrospinal fluid (CSF) using the tissue-based assay (TBA) and cell-based assay (CBA) techniques. Children should also be screened for anti-myelin oligodendrocyte glucoprotein antibodies (anti-MOG). Treatment should be started within the first 4 weeks of symptoms. The first-line option is methylprednisolone plus intravenous immunoglobulin (IVIG) or plasmapheresis, the second-line includes rituximab and/or cyclophosphamide, while third-line treatment options are bortezomib and tocilizumab. Most seizures in AIE are symptomatic, and antiseizure medications may be weaned after the acute stage. In anti-N-methyl-D-aspartate receptor (anti-NMDAR) encephalitis, the panelists have agreed that oral immunosuppressant agents should not be used. Patients should be evaluated at the acute and postacute stages using functional and cognitive scales, such as the Mini-Mental State Examination (MMSE), the Montreal Cognitive Assessment (MoCA), the Modified Rankin Scale (mRS), and the Clinical Assessment Scale in Autoimmune Encephalitis (CASE). Conclusion The present study provides tangible evidence for the effective management of AIE patients within the Brazilian healthcare system. (AIE antigens symptoms complaints disorders young prognosis Academia ABN Sociedade Infantil SBNI, SBNI , SBNI) method 2 neurologists CSF (CSF tissuebased tissue based TBA (TBA cellbased cell CBA (CBA techniques antimyelin anti myelin antiMOG. antiMOG MOG . (anti-MOG) firstline line IVIG (IVIG plasmapheresis secondline second andor cyclophosphamide thirdline third tocilizumab symptomatic stage antiNmethylDaspartate N methyl D aspartate antiNMDAR NMDAR (anti-NMDAR used scales MiniMental Mini Mental MMSE, MMSE (MMSE) MoCA, MoCA (MoCA) mRS, mRS (mRS) CASE. CASE (CASE) system (anti-MOG (MMSE (MoCA (mRS (CASE
Resumo Antecedentes Encefalites autoimunes (EAIs) são um grupo de doenças inflamatórias caracterizadas pela presença de anticorpos contra antígenos neuronais e gliais, que ocasionam sintomas psiquiátricos subagudos, queixas de memória e distúrbios anormais do movimento. A maioria dos pacientes é jovem, e o atraso no tratamento está associado a pior prognóstico. Objetivo Com o apoio da Academia Brasileira de Neurologia (ABN) e da Sociedade Brasileira de Neurologia Infantil (SBNI), desenvolvemos um consenso sobre o diagnóstico e o tratamento da EAIs no Brasil utilizando a metodologia Delphi. Métodos Um total de 25 especialistas, incluindo neurologistas e neurologistas infantis, foram convidados a participar. Resultados Os especialistas concordaram que os pacientes com critérios de possíveis EAIs devem ser submetidos ao rastreio de anticorpos antineuronais no soro e no líquido cefalorraquidiano (LCR) por meio das técnicas de ensaio baseado em tecidos (tissue-based assay, TBA, em inglês) e ensaio baseado em células (cell-based assay, CBA, em inglês). As crianças também devem ser submetidas ao rastreio de de anticorpo contra a glicoproteína da mielina de oligodendrócitos (anti-myelin oligodendrocyte glycoprotein, anti-MOG, em inglês). O tratamento deve ser iniciado dentro das primeiras 4 semanas dos sintomas, sendo as opções de primeira linha metilprednisolona combinada com imunoglobulina intravenosa (IGIV) ou plasmaférese. O tratamento de segunda linha inclui rituximabe e ciclofosfamida. Bortezomib e tocilizumab são opções de tratamento de terceira linha. A maioria das crises epilépticas nas EAIs são sintomáticas, e os fármacos anticrise podem ser desmamadas após a fase aguda. Em relação à encefalite antirreceptor de N-metil-D-aspartato (anti-N-methyl-D-aspartate receptor, anti-NMDAR, em inglês), os especialistas concordaram que agentes imunossupressores orais não devem ser usados. Os pacientes devem ser avaliados na fase aguda e pós-aguda mediante escalas funcionais e cognitivas, como Mini-Mental State Examination (MMSE), Montreal Cognitive Assessment (MoCA), Modified Rankin Scale (mRS), e Clinical Assessment Scale in Autoimmune Encephalitis (CASE). Conclusão Esta pesquisa oferece evidências tangíveis do manejo efetivo de pacientes com EAIs no sistema de saúde Brasileiro. (EAIs gliais subagudos movimento jovem prognóstico ABN (ABN SBNI, SBNI , (SBNI) Delphi 2 infantis participar LCR (LCR tissuebased tissue based assay TBA inglês cellbased cell CBA inglês. . antimyelin anti myelin glycoprotein antiMOG, antiMOG MOG, MOG anti-MOG IGIV (IGIV plasmaférese ciclofosfamida sintomáticas NmetilDaspartato N metil D aspartato antiNmethylDaspartate methyl aspartate receptor antiNMDAR, antiNMDAR NMDAR, NMDAR anti-NMDAR inglês, usados pósaguda pós cognitivas MiniMental Mini Mental MMSE, MMSE (MMSE) MoCA, MoCA (MoCA) mRS, mRS (mRS) CASE. CASE (CASE) Brasileiro (SBNI (MMSE (MoCA (mRS (CASE
8.
Catálogo Taxonômico da Fauna do Brasil: Setting the baseline knowledge on the animal diversity in Brazil Brasil
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Boeger, Walter A.
; Valim, Michel P.
; Zaher, Hussam
; Rafael, José A.
; Forzza, Rafaela C.
; Percequillo, Alexandre R.
; Serejo, Cristiana S.
; Garraffoni, André R.S.
; Santos, Adalberto J.
; Slipinski, Adam
; Linzmeier, Adelita M.
; Calor, Adolfo R.
; Garda, Adrian A.
; Kury, Adriano B.
; Fernandes, Agatha C.S.
; Agudo-Padrón, Aisur I.
; Akama, Alberto
; Silva Neto, Alberto M. da
; Burbano, Alejandro L.
; Menezes, Aleksandra
; Pereira-Colavite, Alessandre
; Anichtchenko, Alexander
; Lees, Alexander C.
; Bezerra, Alexandra M.R.
; Domahovski, Alexandre C.
; Pimenta, Alexandre D.
; Aleixo, Alexandre L.P.
; Marceniuk, Alexandre P.
; Paula, Alexandre S. de
; Somavilla, Alexandre
; Specht, Alexandre
; Camargo, Alexssandro
; Newton, Alfred F.
; Silva, Aline A.S. da
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; Aragão, Allan C.
; Santos, Allan P.M.
; Migotto, Alvaro E.
; Mendes, Amanda C.
; Cunha, Amanda
; Chagas Júnior, Amazonas
; Sousa, Ana A.T. de
; Pavan, Ana C.
; Almeida, Ana C.S.
; Peronti, Ana L.B.G.
; Henriques-Oliveira, Ana L.
; Prudente, Ana L.
; Tourinho, Ana L.
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; Dornellas, Ana P.S.
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; Lima, Aurino F. de
; Barros, Ávyla R. de A.
; Brito, Ayrton do R.
; Romera, Bárbara L.V.
; Vasconcelos, Beatriz M.C. de
; Frable, Benjamin W.
; Santos, Bernardo F.
; Ferraz, Bernardo R.
; Rosa, Brunno B.
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; Bellini, Bruno C.
; Clarkson, Bruno
; Oliveira, Bruno G. de
; Corrêa, Caio C.D.
; Martins, Caleb C.
; Castro-Guedes, Camila F. de
; Souto, Camilla
; Bicho, Carla de L.
; Cunha, Carlo M.
; Barboza, Carlos A. de M.
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; Barreto, Carlos
; Santana, Carlos D.C.M. de
; Agne, Carlos E.Q.
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; Flechtmann, Carlos H.W.
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; Margaría, Cecilia B.
; Waichert, Cecilia
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; Haddad, Célio F.B.
; Azevedo, Celso O.
; Benetti, Cesar J.
; Santos, Charles M.D. dos
; Bartlett, Charles R.
; Bonvicino, Cibele
; Ribeiro-Costa, Cibele S.
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; Justino, Cíntia E.L.
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; Carvalho, Claudio J.B. de
; Gonçalves, Clayton C.
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; Schwertner, Cristiano F.
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; Queiroz, Dalva L. de
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; Garcia, Deivys M.A.
; Baêta, Délio
; Ferreira, Denise N.M.
; Rueda-Ramírez, Diana
; Fachin, Diego A.
; Souza, Diego de S.
; Rodrigues, Diego F.
; Pádua, Diego G. de
; Barbosa, Diego N.
; Dolibaina, Diego R.
; Amaral, Diogo C.
; Chandler, Donald S.
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; Caron, Edilson
; Carvalho, Edrielly
; Adriano, Edson A.
; Abreu Júnior, Edson F. de
; Pereira, Edson H.L.
; Viegas, Eduarda F.G.
; Carneiro, Eduardo
; Colley, Eduardo
; Eizirik, Eduardo
; Santos, Eduardo F. dos
; Shimbori, Eduardo M.
; Suárez-Morales, Eduardo
; Arruda, Eliane P. de
; Chiquito, Elisandra A.
; Lima, Élison F.B.
; Castro, Elizeu B. de
; Orlandin, Elton
; Nascimento, Elynton A. do
; Razzolini, Emanuel
; Gama, Emanuel R.R.
; Araujo, Enilma M. de
; Nishiyama, Eric Y.
; Spiessberger, Erich L.
; Santos, Érika C.L. dos
; Contreras, Eugenia F.
; Galati, Eunice A.B.
; Oliveira Junior, Evaldo C. de
; Gallardo, Fabiana
; Hernandes, Fabio A.
; Lansac-Tôha, Fábio A.
; Pitombo, Fabio B.
; Dario, Fabio Di
; Santos, Fábio L. dos
; Mauro, Fabio
; Nascimento, Fabio O. do
; Olmos, Fabio
; Amaral, Fabio R.
; Schunck, Fabio
; Godoi, Fábio S. P. de
; Machado, Fabrizio M.
; Barbo, Fausto E.
; Agrain, Federico A.
; Ribeiro, Felipe B.
; Moreira, Felipe F.F.
; Barbosa, Felipe F.
; Silva, Fenanda S.
; Cavalcanti, Fernanda F.
; Straube, Fernando C.
; Carbayo, Fernando
; Carvalho Filho, Fernando
; Zanella, Fernando C.V.
; Jacinavicius, Fernando de C.
; Farache, Fernando H.A.
; Leivas, Fernando
; Dias, Fernando M.S.
; Mantellato, Fernando
; Vaz-de-Mello, Fernando Z.
; Gudin, Filipe M.
; Albuquerque, Flávio
; Molina, Flavio B.
; Passos, Flávio D.
; Shockley, Floyd W.
; Pinheiro, Francielly F.
; Mello, Francisco de A.G. de
; Nascimento, Francisco E. de L.
; Franco, Francisco L.
; Oliveira, Francisco L. de
; Melo, Francisco T. de V.
; Quijano, Freddy R.B.
; Salles, Frederico F.
; Biffi, Gabriel
; Queiroz, Gabriel C.
; Bizarro, Gabriel L.
; Hrycyna, Gabriela
; Leviski, Gabriela
; Powell, Gareth S.
; Santos, Geane B. dos
; Morse, Geoffrey E.
; Brown, George
; Mattox, George M.T.
; Zimbrão, Geraldo
; Carvalho, Gervásio S.
; Miranda, Gil F.G.
; Moraes, Gilberto J. de
; Lourido, Gilcélia M.
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; Montingelli, Giovanna G.
; Maurício, Giovanni N.
; Marconato, Gláucia
; Lopez, Guilherme E.L.
; Silva, Guilherme L. da
; Muricy, Guilherme
; Brito, Guilherme R.R.
; Garbino, Guilherme S.T.
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; Proctor, Heather C.
; Gil-Santana, Helcio R.
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; Gonçalves, Igor de S.
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; Oliveira, Ismael B. de
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; Fernandes, Itanna O.
; Golfetti, Ivan F.
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; Oliveira, Ivo de S.
; Delabie, Jacques H.C.
; Oliveira, Jader de
; Prando, Jadila S.
; Patton, James L.
; Bitencourt, Jamille de A.
; Silva, Janaina M.
; Santos, Jandir C.
; Arruda, Janine O.
; Valderrama, Jefferson S.
; Dalapicolla, Jeronymo
; Oliveira, Jéssica P.
; Hájek, Jiri
; Morselli, João P.
; Narita, João P.
; Martin, João P.I.
; Grazia, Jocélia
; McHugh, Joe
; Cherem, Jorge J.
; Farias Júnior, José A.S.
; Fernandes, Jose A.M.
; Pacheco, José F.
; Birindelli, José L.O.
; Rezende, José M.
; Avendaño, Jose M.
; Duarte, José M. Barbanti
; Ribeiro, José R. Inácio
; Mermudes, José R.M.
; Pujol-Luz, José R.
; Santos, Josenilson R. dos
; Câmara, Josenir T.
; Teixeira, Joyce A.
; Prado, Joyce R. do
; Botero, Juan P.
; Almeida, Julia C.
; Kohler, Julia
; Gonçalves, Julia P.
; Beneti, Julia S.
; Donahue, Julian P.
; Alvim, Juliana
; Almeida, Juliana C.
; Segadilha, Juliana L.
; Wingert, Juliana M.
; Barbosa, Julianna F.
; Ferrer, Juliano
; Santos, Juliano F. dos
; Kuabara, Kamila M.D.
; Nascimento, Karine B.
; Schoeninger, Karine
; Campião, Karla M.
; Soares, Karla
; Zilch, Kássia
; Barão, Kim R.
; Teixeira, Larissa
; Sousa, Laura D. do N.M. de
; Dumas, Leandro L.
; Vieira, Leandro M.
; Azevedo, Leonardo H.G.
; Carvalho, Leonardo S.
; Souza, Leonardo S. de
; Rocha, Leonardo S.G.
; Bernardi, Leopoldo F.O.
; Vieira, Letícia M.
; Johann, Liana
; Salvatierra, Lidianne
; Oliveira, Livia de M.
; Loureiro, Lourdes M.A. El-moor
; Barreto, Luana B.
; Barros, Luana M.
; Lecci, Lucas
; Camargos, Lucas M. de
; Lima, Lucas R.C.
; Almeida, Lucia M.
; Martins, Luciana R.
; Marinoni, Luciane
; Moura, Luciano de A.
; Lima, Luciano
; Naka, Luciano N.
; Miranda, Lucília S.
; Salik, Lucy M.
; Bezerra, Luis E.A.
; Silveira, Luis F.
; Campos, Luiz A.
; Castro, Luiz A.S. de
; Pinho, Luiz C.
; Silveira, Luiz F.L.
; Iniesta, Luiz F.M.
; Tencatt, Luiz F.C.
; Simone, Luiz R.L.
; Malabarba, Luiz R.
; Cruz, Luiza S. da
; Sekerka, Lukas
; Barros, Lurdiana D.
; Santos, Luziany Q.
; Skoracki, Maciej
; Correia, Maira A.
; Uchoa, Manoel A.
; Andrade, Manuella F.G.
; Hermes, Marcel G.
; Miranda, Marcel S.
; Araújo, Marcel S. de
; Monné, Marcela L.
; Labruna, Marcelo B.
; Santis, Marcelo D. de
; Duarte, Marcelo
; Knoff, Marcelo
; Nogueira, Marcelo
; Britto, Marcelo R. de
; Melo, Marcelo R.S. de
; Carvalho, Marcelo R. de
; Tavares, Marcelo T.
; Kitahara, Marcelo V.
; Justo, Marcia C.N.
; Botelho, Marcia J.C.
; Couri, Márcia S.
; Borges-Martins, Márcio
; Felix, Márcio
; Oliveira, Marcio L. de
; Bologna, Marco A.
; Gottschalk, Marco S.
; Tavares, Marcos D.S.
; Lhano, Marcos G.
; Bevilaqua, Marcus
; Santos, Marcus T.T.
; Domingues, Marcus V.
; Sallum, Maria A.M.
; Digiani, María C.
; Santarém, Maria C.A.
; Nascimento, Maria C. do
; Becerril, María de los A.M.
; Santos, Maria E.A. dos
; Passos, Maria I. da S. dos
; Felippe-Bauer, Maria L.
; Cherman, Mariana A.
; Terossi, Mariana
; Bartz, Marie L.C.
; Barbosa, Marina F. de C.
; Loeb, Marina V.
; Cohn-Haft, Mario
; Cupello, Mario
; Martins, Marlúcia B.
; Christofersen, Martin L.
; Bento, Matheus
; Rocha, Matheus dos S.
; Martins, Maurício L.
; Segura, Melissa O.
; Cardenas, Melissa Q.
; Duarte, Mércia E.
; Ivie, Michael A.
; Mincarone, Michael M.
; Borges, Michela
; Monné, Miguel A.
; Casagrande, Mirna M.
; Fernandez, Monica A.
; Piovesan, Mônica
; Menezes, Naércio A.
; Benaim, Natalia P.
; Reategui, Natália S.
; Pedro, Natan C.
; Pecly, Nathalia H.
; Ferreira Júnior, Nelson
; Silva Júnior, Nelson J. da
; Perioto, Nelson W.
; Hamada, Neusa
; Degallier, Nicolas
; Chao, Ning L.
; Ferla, Noeli J.
; Mielke, Olaf H.H.
; Evangelista, Olivia
; Shibatta, Oscar A.
; Oliveira, Otto M.P.
; Albornoz, Pablo C.L.
; Dellapé, Pablo M.
; Gonçalves, Pablo R.
; Shimabukuro, Paloma H.F.
; Grossi, Paschoal
; Rodrigues, Patrícia E. da S.
; Lima, Patricia O.V.
; Velazco, Paul
; Santos, Paula B. dos
; Araújo, Paula B.
; Silva, Paula K.R.
; Riccardi, Paula R.
; Garcia, Paulo C. de A.
; Passos, Paulo G.H.
; Corgosinho, Paulo H.C.
; Lucinda, Paulo
; Costa, Paulo M.S.
; Alves, Paulo P.
; Roth, Paulo R. de O.
; Coelho, Paulo R.S.
; Duarte, Paulo R.M.
; Carvalho, Pedro F. de
; Gnaspini, Pedro
; Souza-Dias, Pedro G.B.
; Linardi, Pedro M.
; Bartholomay, Pedro R.
; Demite, Peterson R.
; Bulirsch, Petr
; Boll, Piter K.
; Pereira, Rachel M.M.
; Silva, Rafael A.P.F.
; Moura, Rafael B. de
; Boldrini, Rafael
; Silva, Rafaela A. da
; Falaschi, Rafaela L.
; Cordeiro, Ralf T.S.
; Mello, Ramon J.C.L.
; Singer, Randal A.
; Querino, Ranyse B.
; Heleodoro, Raphael A.
; Castilho, Raphael de C.
; Constantino, Reginaldo
; Guedes, Reinaldo C.
; Carrenho, Renan
; Gomes, Renata S.
; Gregorin, Renato
; Machado, Renato J.P.
; Bérnils, Renato S.
; Capellari, Renato S.
; Silva, Ricardo B.
; Kawada, Ricardo
; Dias, Ricardo M.
; Siewert, Ricardo
; Brugnera, Ricaro
; Leschen, Richard A.B.
; Constantin, Robert
; Robbins, Robert
; Pinto, Roberta R.
; Reis, Roberto E. dos
; Ramos, Robson T. da C.
; Cavichioli, Rodney R.
; Barros, Rodolfo C. de
; Caires, Rodrigo A.
; Salvador, Rodrigo B.
; Marques, Rodrigo C.
; Araújo, Rodrigo C.
; Araujo, Rodrigo de O.
; Dios, Rodrigo de V.P.
; Johnsson, Rodrigo
; Feitosa, Rodrigo M.
; Hutchings, Roger W.
; Lara, Rogéria I.R.
; Rossi, Rogério V.
; Gerstmeier, Roland
; Ochoa, Ronald
; Hutchings, Rosa S.G.
; Ale-Rocha, Rosaly
; Rocha, Rosana M. da
; Tidon, Rosana
; Brito, Rosangela
; Pellens, Roseli
; Santos, Sabrina R. dos
; Santos, Sandra D. dos
; Paiva, Sandra V.
; Santos, Sandro
; Oliveira, Sarah S. de
; Costa, Sávio C.
; Gardner, Scott L.
; Leal, Sebastián A. Muñoz
; Aloquio, Sergio
; Bonecker, Sergio L.C.
; Bueno, Sergio L. de S.
; Almeida, Sérgio M. de
; Stampar, Sérgio N.
; Andena, Sérgio R.
; Posso, Sergio R.
; Lima, Sheila P.
; Gadelha, Sian de S.
; Thiengo, Silvana C.
; Cohen, Simone C.
; Brandão, Simone N.
; Rosa, Simone P.
; Ribeiro, Síria L.B.
; Letana, Sócrates D.
; Santos, Sonia B. dos
; Andrade, Sonia C.S.
; Dávila, Stephane
; Vaz, Stéphanie
; Peck, Stewart B.
; Christo, Susete W.
; Cunha, Suzan B.Z.
; Gomes, Suzete R.
; Duarte, Tácio
; Madeira-Ott, Taís
; Marques, Taísa
; Roell, Talita
; Lima, Tarcilla C. de
; Sepulveda, Tatiana A.
; Maria, Tatiana F.
; Ruschel, Tatiana P.
; Rodrigues, Thaiana
; Marinho, Thais A.
; Almeida, Thaís M. de
; Miranda, Thaís P.
; Freitas, Thales R.O.
; Pereira, Thalles P.L.
; Zacca, Thamara
; Pacheco, Thaynara L.
; Martins, Thiago F.
; Alvarenga, Thiago M.
; Carvalho, Thiago R. de
; Polizei, Thiago T.S.
; McElrath, Thomas C.
; Henry, Thomas
; Pikart, Tiago G.
; Porto, Tiago J.
; Krolow, Tiago K.
; Carvalho, Tiago P.
; Lotufo, Tito M. da C.
; Caramaschi, Ulisses
; Pinheiro, Ulisses dos S.
; Pardiñas, Ulyses F.J.
; Maia, Valéria C.
; Tavares, Valeria
; Costa, Valmir A.
; Amaral, Vanessa S. do
; Silva, Vera C.
; Wolff, Vera R. dos S.
; Slobodian, Verônica
; Silva, Vinícius B. da
; Espíndola, Vinicius C.
; Costa-Silva, Vinicius da
; Bertaco, Vinicius de A.
; Padula, Vinícius
; Ferreira, Vinicius S.
; Silva, Vitor C.P. da
; Piacentini, Vítor de Q.
; Sandoval-Gómez, Vivian E.
; Trevine, Vivian
; Sousa, Viviane R.
; Sant’Anna, Vivianne B. de
; Mathis, Wayne N.
; Souza, Wesley de O.
; Colombo, Wesley D.
; Tomaszewska, Wioletta
; Wosiacki, Wolmar B.
; Ovando, Ximena M.C.
; Leite, Yuri L.R.
.
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ABSTRACT The limited temporal completeness and taxonomic accuracy of species lists, made available in a traditional manner in scientific publications, has always represented a problem. These lists are invariably limited to a few taxonomic groups and do not represent up-to-date knowledge of all species and classifications. In this context, the Brazilian megadiverse fauna is no exception, and the Catálogo Taxonômico da Fauna do Brasil (CTFB) (http://fauna.jbrj.gov.br/), made public in 2015, represents a database on biodiversity anchored on a list of valid and expertly recognized scientific names of animals in Brazil. The CTFB is updated in near real time by a team of more than 800 specialists. By January 1, 2024, the CTFB compiled 133,691 nominal species, with 125,138 that were considered valid. Most of the valid species were arthropods (82.3%, with more than 102,000 species) and chordates (7.69%, with over 11,000 species). These taxa were followed by a cluster composed of Mollusca (3,567 species), Platyhelminthes (2,292 species), Annelida (1,833 species), and Nematoda (1,447 species). All remaining groups had less than 1,000 species reported in Brazil, with Cnidaria (831 species), Porifera (628 species), Rotifera (606 species), and Bryozoa (520 species) representing those with more than 500 species. Analysis of the CTFB database can facilitate and direct efforts towards the discovery of new species in Brazil, but it is also fundamental in providing the best available list of valid nominal species to users, including those in science, health, conservation efforts, and any initiative involving animals. The importance of the CTFB is evidenced by the elevated number of citations in the scientific literature in diverse areas of biology, law, anthropology, education, forensic science, and veterinary science, among others. publications problem uptodate up date classifications context exception (CTFB http//fauna.jbrj.gov.br/, httpfaunajbrjgovbr http //fauna.jbrj.gov.br/ , jbrj gov br (http://fauna.jbrj.gov.br/) 2015 Brazil 80 specialists 1 2024 133691 133 691 133,69 125138 125 138 125,13 82.3%, 823 82 3 (82.3% 102000 102 000 102,00 7.69%, 769 7 69 (7.69% 11000 11 11,00 . 3,567 3567 567 (3,56 2,292 2292 2 292 (2,29 1,833 1833 833 (1,83 1,447 1447 447 (1,44 1000 1,00 831 (83 628 (62 606 (60 520 (52 50 users science health biology law anthropology education others http//fauna.jbrj.gov.br/ faunajbrjgovbr //fauna.jbrj.gov.br (http://fauna.jbrj.gov.br/ 201 8 202 13369 13 133,6 12513 12 125,1 82.3% (82.3 10200 10 00 102,0 7.69% 76 6 (7.69 1100 11,0 3,56 356 56 (3,5 2,29 229 29 (2,2 1,83 183 83 (1,8 1,44 144 44 (1,4 100 1,0 (8 62 (6 60 52 (5 5 http//fauna.jbrj.gov.br (http://fauna.jbrj.gov.br 20 1336 133, 1251 125, 82.3 (82. 1020 0 102, 7.69 (7.6 110 11, 3,5 35 (3, 2,2 22 (2, 1,8 18 (1, 1,4 14 4 ( 82. (82 7.6 (7. 3, (3 2, (2 (1 7. (7
9.
Characterization of Brazilian Buriti oil biomaterial: the influence on the physical, chemical properties and behaviour of Goat Wharton’s jelly mesenchymal stem cells biomaterial physical Whartons Wharton s
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Carvalho, Camila Ernanda Sousa de
; Reis, Fernando da Silva
; Silva, Elis Rosélia Dutra de Freitas Siqueira
; Bezerra, Dayseanny de Oliveira
; Pacheco, Isnayra Kerolaynne Carneiro
; Fialho, Ana Cristina Vasconcelos
; Matos, José Milton Elias de
; Melo, Wanderson Gabriel Gomes de
; Leite, Yulla Klinger Pereira de Carvalho
; Argôlo Neto, Napoleão Martins
; Carvalho, Maria Acelina Martins de
.
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Abstract The Brazilian Buriti oil presents low extraction costs and relevant antioxidant properties. Thus, this work aimed to analyze Buriti oil biomaterial (BB), within its physicochemical properties, biocompatibility and cellular integration, with the purpose to the use as a growth matrix for Goat Wharton’s jelly mesenchymal stem cells. Biomaterials were produced from Buriti oil polymer (Mauritia flexuosa), for it’s characterization were performed Infrared Region Spectroscopy (FTIR) and Thermogravimetric Analysis (TG and DTG). The biointegration was analyzed by Scanning Electron Microscopy (SEM) and histological techniques. In order to investigate biocompatibility, MTT (3-(4,5-dimetil-2-tiazolil)-2,5-difenil-2H-tetrazólio) test and hemolytic activity tests were performed. The activation capacity of immune system cellswas measured by phagocytic capacity assay and nitric oxide synthesis . The BB presented an amorphous composition, with high thermal stability and high water expansion capacity, a surface with micro and macropores, and good adhesion of Wharton’s jelly mesenchymal stem cells (MSCWJ). We verified the absence of cytotoxicity and hemolytic activity, in addition, BB did not stimulate the activation of macrophages. Proving to be a safe material for direct cultivation and also for manufacturing of compounds used for in vivo applications. properties Thus BB, , (BB) integration Whartons Wharton s Mauritia flexuosa, flexuosa flexuosa) it FTIR (FTIR TG DTG. DTG DTG) SEM (SEM techniques 34,5dimetil2tiazolil2,5difenil2Htetrazólio 345dimetil2tiazolil25difenil2Htetrazólio dimetiltiazolildifenilHtetrazólio 3 4,5 dimetil 2 tiazolil 2,5 difenil 2H tetrazólio 4 5 H (3-(4,5-dimetil-2-tiazolil)-2,5-difenil-2H-tetrazólio composition macropores MSCWJ. MSCWJ (MSCWJ) addition macrophages applications (BB 34 5dimetil2tiazolil2 5difenil2Htetrazólio Htetrazólio 45 4, 25 2, (MSCWJ dimetiltiazolil 5dimetil2tiazolil difenilHtetrazólio
10.
Concepções sobre tratamento e diagnóstico da tuberculose pulmonar para quem a vivencia
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Teixeira, Lucas Miléo
; Palmeira, Iaci Proença
; Matos, Widson Davi Vaz de
; Sousa, Rosimere de Freitas de
; Monteiro, Yasmin Cristino
; Vale, Camila Carvalho do
; Oliveira, Leticia Lima
.
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Resumo Objetivos analisar as concepções de pessoas que vivenciam o tratamento e o diagnóstico da tuberculose pulmonar. Método trata-se de uma pesquisa descritiva e exploratória, com abordagem qualitativa, desenvolvida em um Centro de Saúde Escola de Belém (Pará) com 30 pacientes. Os dados foram coletados durante o período de setembro de 2019 a janeiro de 2020 por meio de entrevista semiestruturada com o auxílio de um roteiro contendo seis perguntas, assim como a observação das informações contidas no prontuário e no livro de controle de registro da tuberculose. Para a análise dos resultados, foi utilizada a técnica de Análise de Conteúdo segundo a perspectiva de Bardin. Resultado identificou-se que o reduzido conhecimento sobre a doença e a presença de concepções negativas influenciam, de forma significativa, a busca por cuidados ou a adesão ao tratamento, interferindo nas atividades diárias e laborais. Conclusão conclui-se que persiste a necessidade de os doentes (res)significarem a tuberculose durante o tratamento, sendo fundamental que a equipe de saúde conheça tais concepções, a fim de subsidiar cuidados que contemplem aspectos físicos e biopsicossociais ante o Programa de Controle da Tuberculose da unidade.
Abstract Objectives to analyze the conceptions of people experiencing treatment and diagnosis of pulmonary tuberculosis. Method this is a descriptive and exploratory research with a qualitative approach, developed in a School Health Center of Belém (Pará) with 30 patients. Data was collected during the period from September 2019 to January 2020 through a semi-structured interview with the aid of a script containing six questions, as well as the observation of the information contained in the medical record and in the tuberculosis record control book. For the analysis of the results, the Content Analysis technique was used according to Bardin's perspective. Result it was identified that the reduced knowledge about the disease and the presence of negative conceptions influence, in a significant way, the search for care or the adherence to treatment, interfering in daily and work activities. Conclusion it is concluded that the need for patients to (re)mean tuberculosis during treatment persists, and it is essential that the health team knows such conceptions in order to provide care that contemplates physical and bio-psychosocial aspects before the Tuberculosis Control Program of the unit.
Resumen Objetivos analizar las concepciones de las personas que viven el tratamiento y diagnóstico de la tuberculosis pulmonar. Método se trata de una investigación descriptiva y exploratoria con abordaje cualitativo, desarrollada en un Centro de Salud Escolar de Belém (Pará), con 30 pacientes. Los datos fueron recogidos durante el período de septiembre de 2019 a enero de 2020 a través de una entrevista semiestructurada con la ayuda de un guion con seis preguntas, así como la observación de las informaciones contenidas en el prontuario y en el libro de control de registro de la tuberculosis. Para analizar los resultados se utilizó una técnica de análisis de contenido según la perspectiva de Bardin. Resultado se identificó que el escaso conocimiento sobre la enfermedad y la presencia de concepciones negativas influyen, de forma significativa, en la búsqueda de cuidados o la adhesión al tratamiento, interfiriendo en las actividades diarias y laborales. Conclusión se concluye que persiste la necesidad de los pacientes de (re)significar la tuberculosis durante el tratamiento, y del equipo tratante, de conocer tales concepciones, para subsidiar cuidados que contemplen aspectos físicos y biopsicosociales ante el Programa de Control de la Tuberculosis de la unidad.
11.
IMPACTO-MR: um estudo brasileiro de plataforma nacional para avaliar infecções e multirresistência em unidades de terapia intensiva IMPACTOMR IMPACTO MR IMPACTO-MR
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Tomazini, Bruno M
; Nassar Jr, Antonio Paulo
; Lisboa, Thiago Costa
; Azevedo, Luciano César Pontes de
; Veiga, Viviane Cordeiro
; Catarino, Daniela Ghidetti Mangas
; Fogazzi, Debora Vacaro
; Arns, Beatriz
; Piastrelli, Filipe Teixeira
; Dietrich, Camila
; Negrelli, Karina Leal
; Jesuíno, Isabella de Andrade
; Reis, Luiz Fernando Lima
; Mattos, Renata Rodrigues de
; Pinheiro, Carla Cristina Gomes
; Luz, Mariane Nascimento
; Spadoni, Clayse Carla da Silva
; Moro, Elisângela Emilene
; Bueno, Flávia Regina
; Sampaio, Camila Santana Justo Cintra
; Silva, Débora Patrício
; Baldassare, Franca Pellison
; Silva, Ana Cecilia Alcantara
; Veiga, Thabata
; Barbante, Leticia
; Lambauer, Marianne
; Campos, Viviane Bezerra
; Santos, Elton
; Santos, Renato Hideo Nakawaga
; Laranjeiras, Ligia Nasi
; Valeis, Nanci
; Santucci, Eliana
; Miranda, Tamiris Abait
; Patrocínio, Ana Cristina Lagoeiro do
; Carvalho, Andréa de
; Sousa, Eduvirgens Maria Couto de
; Sousa, Ancelmo Honorato Ferraz de
; Malheiro, Daniel Tavares
; Bezerra, Isabella Lott
; Rodrigues, Mirian Batista
; Malicia, Julliana Chicuta
; Silva, Sabrina Souza da
; Gimenes, Bruna dos Passos
; Sesin, Guilhermo Prates
; Zavascki, Alexandre Prehn
; Sganzerla, Daniel
; Medeiros, Gregory Saraiva
; Santos, Rosa da Rosa Minho dos
; Silva, Fernanda Kelly Romeiro
; Cheno, Maysa Yukari
; Abrahão, Carolinne Ferreira
; Oliveira Junior, Haliton Alves de
; Rocha, Leonardo Lima
; Nunes Neto, Pedro Aniceto
; Pereira, Valéria Chagas
; Paciência, Luis Eduardo Miranda
; Bueno, Elaine Silva
; Caser, Eliana Bernadete
; Ribeiro, Larissa Zuqui
; Fernandes, Caio Cesar Ferreira
; Garcia, Juliana Mazzei
; Silva, Vanildes de Fátima Fernandes
; Santos, Alisson Junior dos
; Machado, Flávia Ribeiro
; Souza, Maria Aparecida de
; Ferronato, Bianca Ramos
; Urbano, Hugo Corrêa de Andrade
; Moreira, Danielle Conceição Aparecida
; Souza-Dantas, Vicente Cés de
; Duarte, Diego Meireles
; Coelho, Juliana
; Figueiredo, Rodrigo Cruvinel
; Foreque, Fernanda
; Romano, Thiago Gomes
; Cubos, Daniel
; Spirale, Vladimir Miguel
; Nogueira, Roberta Schiavon
; Maia, Israel Silva
; Zandonai, Cassio Luis
; Lovato, Wilson José
; Cerantola, Rodrigo Barbosa
; Toledo, Tatiana Gozzi Pancev
; Tomba, Pablo Oscar
; Almeida, Joyce Ramos de
; Sanches, Luciana Coelho
; Pierini, Leticia
; Cunha, Mariana
; Sousa, Michelle Tereza
; Azevedo, Bruna
; Dal-Pizzol, Felipe
; Damasio, Danusa de Castro
; Bainy, Marina Peres
; Beduhn, Dagoberta Alves Vieira
; Jatobá, Joana D’Arc Vila Nova
; Moura, Maria Tereza Farias de
; Rego, Leila Rezegue de Moraes
; Silva, Adria Vanessa da
; Oliveira, Luana Pontes
; Sodré Filho, Eliene Sá
; Santos, Silvana Soares dos
; Neves, Itallo de Lima
; Leão, Vanessa Cristina de Aquino
; Paes, João Lucidio Lobato
; Silva, Marielle Cristina Mendes
; Oliveira, Cláudio Dornas de
; Santiago, Raquel Caldeira Brant
; Paranhos, Jorge Luiz da Rocha
; Wiermann, Iany Grinezia da Silva
; Pedroso, Durval Ferreira Fonseca
; Sawada, Priscilla Yoshiko
; Prestes, Rejane Martins
; Nascimento, Glícia Cardoso
; Grion, Cintia Magalhães Carvalho
; Carrilho, Claudia Maria Dantas de Maio
; Dantas, Roberta Lacerda Almeida de Miranda
; Silva, Eliane Pereira
; Silva, Antônio Carlos da
; Oliveira, Sheila Mara Bezerra de
; Golin, Nicole Alberti
; Tregnago, Rogerio
; Lima, Valéria Paes
; Silva, Kamilla Grasielle Nunes da
; Boschi, Emerson
; Buffon, Viviane
; Machado, André Sant’Ana
; Capeletti, Leticia
; Foernges, Rafael Botelho
; Carvalho, Andréia Schubert de
; Oliveira Junior, Lúcio Couto de
; Oliveira, Daniela Cunha de
; Silva, Everton Macêdo
; Ribeiro, Julival
; Pereira, Francielle Constantino
; Salgado, Fernanda Borges
; Deutschendorf, Caroline
; Silva, Cristofer Farias da
; Gobatto, Andre Luiz Nunes
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; Alvaia, Natália Oliveira Santos
; Souza, Roberta Machado de
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; Melo, Rodrigo Morel Vieira de
; Passos, Luiz Carlos Santana
; Vidal, Claudia Fernanda de Lacerda
; Rodrigues, Fernanda Lopes de Albuquerque
; Kurtz, Pedro
; Shinotsuka, Cássia Righy
; Tavares, Maria Brandão
; Santana, Igor das Virgens
; Gavinho, Luciana Macedo da Silva
; Nascimento, Alaís Brito
; Pereira, Adriano J
; Cavalcanti, Alexandre Biasi
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ABSTRACT Objective: To describe the IMPACTO-MR, a Brazilian nationwide intensive care unit platform study focused on the impact of health care-associated infections due to multidrug-resistant bacteria. Methods: We described the IMPACTO-MR platform, its development, criteria for intensive care unit selection, characterization of core data collection, objectives, and future research projects to be held within the platform. Results: The core data were collected using the Epimed Monitor System® and consisted of demographic data, comorbidity data, functional status, clinical scores, admission diagnosis and secondary diagnoses, laboratory, clinical, and microbiological data, and organ support during intensive care unit stay, among others. From October 2019 to December 2020, 33,983 patients from 51 intensive care units were included in the core database. Conclusion: The IMPACTO-MR platform is a nationwide Brazilian intensive care unit clinical database focused on researching the impact of health care-associated infections due to multidrug-resistant bacteria. This platform provides data for individual intensive care unit development and research and multicenter observational and prospective trials. Objective IMPACTOMR, IMPACTOMR IMPACTO MR, MR careassociated associated multidrugresistant multidrug resistant bacteria Methods selection collection objectives Results System status scores diagnoses laboratory stay others 201 2020 33983 33 983 33,98 5 Conclusion trials 20 202 3398 3 98 33,9 2 339 9 33,
RESUMO Objetivo: Descrever o IMPACTO-MR, um estudo brasileiro de plataforma nacional em unidades de terapia intensiva focado no impacto das infecções por bactérias multirresistentes relacionadas à assistência à saúde. Métodos: Descrevemos a plataforma IMPACTO-MR, seu desenvolvimento, critérios para seleção das unidades de terapia intensiva, caracterização da coleta de dados, objetivos e projetos de pesquisa futuros a serem realizados na plataforma. Resultados: Os dados principais foram coletados por meio do Epimed Monitor System® e consistiram em dados demográficos, dados de comorbidades, estado funcional, escores clínicos, diagnóstico de internação e diagnósticos secundários, dados laboratoriais, clínicos e microbiológicos e suporte de órgãos durante a internação na unidade de terapia intensiva, entre outros. De outubro de 2019 a dezembro de 2020, 33.983 pacientes de 51 unidades de terapia intensiva foram incluídos no banco de dados principal. Conclusão: A plataforma IMPACTO-MR é um banco de dados clínico brasileiro de unidades de terapia intensiva focado na pesquisa do impacto das infecções por bactérias multirresistentes relacionadas à assistência à saúde. Essa plataforma fornece dados para o desenvolvimento e pesquisa de unidades de terapia intensiva individuais e ensaios clínicos observacionais e prospectivos multicêntricos. Objetivo IMPACTOMR, IMPACTOMR IMPACTO MR, MR saúde Métodos Resultados System demográficos comorbidades funcional secundários laboratoriais outros 201 2020 33983 33 983 33.98 5 principal Conclusão multicêntricos 20 202 3398 3 98 33.9 2 339 9 33.
12.
Diferenças Raciais no Controle da Pressão Arterial em Usuários de Anti-Hipertensivos em Monoterapia: Resultados do Estudo ELSA-Brasil
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Sousa, Camila Tavares
; Ribeiro, Antonio
; Barreto, Sandhi Maria
; Giatti, Luana
; Brant, Luisa
; Lotufo, Paulo
; Chor, Dora
; Lopes, Antônio Alberto
; Mengue, Sotero Serrate
; Baldoni, André Oliveira
; Figueiredo, Roberta Carvalho
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Resumo Fundamento Aparentemente, a pior resposta a algumas classes de anti-hipertensivos, especialmente inibidores da enzima conversora da angiotensina e bloqueadores de receptor de angiotensina, pela população negra, explicaria, pelo menos parcialmente, o pior controle da hipertensão entre esses indivíduos. Entretanto, a maioria das evidências vêm de estudos norte-americanos. Objetivos Este estudo tem o objetivo de investigar a associação entre raça/cor da pele autorrelatadas e controle de PA em participantes do Estudo Longitudinal de Saúde do Adulto (ELSA-Brasil) utilizando várias classes de anti-hipertensivos em monoterapia. Métodos O estudo envolveu uma análise transversal, realizada com participantes da linha de base do ELSA-Brasil. O controle de pressão arterial foi a variável de resposta, participantes com valores de PA ≥140/90 mmHg foram considerados descontrolados em relação aos níveis de pressão arterial. A raça/cor da pele foi autorrelatada (branco, pardo, negro). Todos os participantes tiveram que responder perguntas sobre uso contínuo de medicamentos. A associação entre o controle de PA e raça/cor da pele foi estimada por regressão logística. O nível de significância adotado nesse estudo foi de 5%. Resultados Do total de 1.795 usuários de anti-hipertensivos em monoterapia na linha de base, 55,5% se declararam brancos, 27,9%, pardos e 16,7%, negros. Mesmo depois de padronizar em relação a variáveis de confusão, negros em uso de inibidores da enzima conversora de angiotensina (IECA), bloqueadores de receptor de angiotensina (BRA), diuréticos tiazídicos (DIU tiazídicos) e betabloqueadores (BB) in monoterapia tinham controle de pressão arterial pior em comparação a brancos. Conclusões Os resultados deste estudo sugerem que, nesta amostra de brasileiros adultos utilizando anti-hipertensivos em monoterapia, as diferenças de controle de pressão arterial entre os vários grupos raciais não são explicadas pela possível eficácia mais baixa dos IECA e BRA em indivíduos negros.
Abstract Background It seems that the worst response to some classes of antihypertensive drugs, especially angiotensin-converting enzyme inhibitors and angiotensin receptor blockers, on the part of the Black population, would at least partially explain the worse control of hypertension among these individuals. However, most of the evidence comes from American studies. Objectives This study aims to investigate the association between self-reported race/skin color and BP control in participants of the Longitudinal Study of Adult Health (ELSA-Brasil), using different classes of antihypertensive drugs in monotherapy. Methods The study involved a cross-sectional analysis, carried out with participants from the baseline of ELSA-Brasil. Blood pressure control was the response variable, participants with BP values ≥140/90 mmHg were considered out of control in relation to blood pressure levels. Race/skin color was self-reported (White, Brown, Black). All participants were asked about the continuous use of medication. Association between BP control and race/skin color was estimated through logistic regression. The level of significance adopted in this study was of 5%. Results Of the total of 1,795 users of antihypertensive drugs in monotherapy at baseline, 55.5% declared themselves White, 27.9% Brown, and 16.7% Black. Even after adjusting for confounding variables, Blacks using angiotensin converting enzyme inhibitors (ACEI), angiotensin receptor blocker (ARB), thiazide diuretics (thiazide DIU), and beta-blockers (BB) in monotherapy had worse blood pressure control compared to Whites. Conclusions Our results suggest that in this sample of Brazilian adults using antihypertensive drugs in monotherapy, the differences in blood pressure control between different racial groups are not explained by the possible lower effectiveness of ACEIs and ARBs in Black individuals.
13.
[SciELO Preprints] - Prevalence of exposure to violence among adults – Brazil, 2019
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Mascarenhas, Márcio Dênis Medeiros
Melo, Ariel de Sousa
Rodrigues, Malvina Thais Pacheco
Bahia, Camila Alves
Lima, Cheila Marina
Corassa, Rafael Bello
Andrade, Fabiana Martins Dias de
Malta, Deborah Carvalho
Objective: To estimate the prevalence of exposure to violence, characterizing its magnitude, types and occurrence in the adult population in Brazil. Methods: Cross-sectional study with data from the National Health Survey conducted in 2019. The prevalence of violence in the last 12 months and respective 95% confidence intervals (95%CI) were estimated according to sociodemographic variables. Crude prevalence ratios (cPR) were estimated by Poisson regression. Results: The prevalence of exposure to violence among adults in Brazil was 18.3% (95%CI 17.8;18.8) , with a significantly higher frequency among women (19.4%; 95%CI 18.7;20.0), in the 18-29 age group (27.0%; 95%CI 25.7;28.4), in self-declared black people (20.6%; 95%CI 19.3;221.9) and mixed race (19.3%; 95%CI 18.6;20.1) and among inhabitants of the Northeast region (18.7%; 95%CI 18.0;19.5). Among the victims of violence, 15.6% (95%CI 14.2;17.0) sought health care, of which (91.2%; 95%CI 88.1;93.6) were attended. The most reported types of violence were: psychological (17.4%; 95%CI 16.9;17.9), physical (4.1%; 95%CI 3.9;4.4) and sexual (0.8%; 95%CI 0.7;0.9). Men were more exposed to violence with the use of firearms or sharp targets, while women were the predominant victims for all other types and mechanisms of violence. The aggressor most cited was the intimate partner, the most frequent place of occurrence of violence being the residence and public streets/places. Conclusion: In Brazil, violence affected one in five adults. Women, young people and people with black skin were the population segments most exposed to violence, which should be a priority in prevention actions.
Objetivo: Estimar a prevalência de exposição à violência, caracterizando sua magnitude, tipos e ocorrência na população adulta do Brasil. Métodos: Estudo transversal com dados da Pesquisa Nacional de Saúde realizada em 2019. Estimou-se a prevalência de violência nos últimos 12 meses e respectivos intervalos de confiança de 95% (IC95%) segundo variáveis sociodemográficas. Razões de prevalência bruta (RPb) foram estimadas por regressão de Poisson. Resultados: A prevalência de exposição à violência entre adultos no Brasil foi de 18,3% (IC95% 17,8;18,8), com frequência significativamente maior entre as mulheres (19,4%; IC95% 18,7;20,0), no grupo de 18 a 29 anos (27,0%; IC95% 25,7;28,4), nas pessoas autodeclaradas pretas (20,6%; IC95% 19,3;221,9) e pardas (19,3%; IC95% 18,6;20,1) e entre habitantes da região Nordeste (18,7%; IC95% 18,0;19,5). Dentre as vítimas de violência, 15,6% (IC95% 14,2-17,0) procuraram atendimento de saúde, das quais (91,2%; IC95% 88,1;93,6) foram atendidas. Os tipos de violência mais relatados foram: psicológica (17,4%; IC95% 16,9;17,9), física (4,1%; IC95% 3,9;4,4) e sexual (0,8%; IC95% 0,7;0,9). Os homens foram mais expostos à violência com uso de arma de fogo ou objetivos cortantes, enquanto as mulheres foram as vítimas predominantes para todos os demais tipos e mecanismos de violência. O agressor mais citado foi o(a) parceiro(a) íntimo(a), sendo o local mais frequente de ocorrência da violência a residência, vias e locais públicos. Conclusão: No Brasil, a violência afetou um a cada cinco adultos. Mulheres, jovens e pessoas de pele negra foram os segmentos populacionais mais expostos à violência, os quais devem ser prioritários nas ações de prevenção.
14.
Content analysis of clinical indicators for Impaired gas exchange
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Pascoal, Lívia Maia
; Lopes, Marcos Venícios de Oliveira
; Silva, Viviane Martins da
; Diniz, Camila Maciel
; Nunes, Marília Mendes
; Freire, Vanessa Emille Carvalho de Sousa
; Amorim, Beatriz Beltrão
.
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RESUMO Objetivo Analisar a relevância dos indicadores clínicos e a clareza e precisão das definições conceituais e operacionais do diagnóstico Troca de gases prejudicada. Métodos Análise de conteúdo, por 39 juízes enfermeiros, dividida nas fases de definição conceitual do fenômeno de interesse, construção da estrutura do fenômeno de interesse e análise dos juízes sobre a estrutura construída. Resultados Dos 22 indicadores, 21 foram considerados relevantes Troca de gases prejudicada. Os indicadores que obtiveram relevância absoluta foram Cianose, Hipercapnia, Hipoxemia e Taquicardia. O indicador Cefaleia ao acordar não apresentou relevância estatisticamente significante para o diagnóstico. Todas as definições conceituais e operacionais foram claras e precisas. Conclusão Os indicadores elencados para Troca de gases prejudicada foram relevantes ao fenômeno, exceto Cefaleia ao acordar pois não corresponde a uma manifestação segura para identificar o diagnóstico, conforme a análise dos juízes. Cada definição conceitual e operacional foi adequada para seu referido indicador.
ABSTRACT Objective To analyze the relevance of clinical indicators and the clarity and precision of conceptual and operational definitions of the diagnosis Impaired gas exchange. Methods Content analysis, by 39 nurse judges, divided into the phases of conceptual definition of the phenomenon of interest, construction of the structure of the phenomenon of interest and analysis of the judges on the built structure. Results From the 22 indicators, 21 were considered relevant Impaired gas exchange. The indicators that obtained absolute relevance were Cyanosis, Hypercapnia, Hypoxemia and Tachycardia. The indicator Headache upon waking did not show any statistically significant relevance for the diagnosis. All conceptual and operational definitions were clear and precise. Conclusion The indicators listed for Impaired gas exchange were relevant to the phenomenon, except Headache upon waking because it does not correspond to a safe manifestation to identify the diagnosis, according to the analysis of the judges. Each conceptual and operational definition was adequate for its indicator.
RESUMEN Objetivo Analizar la relevancia de los indicadores clínicos y la claridad y precisión de las definiciones conceptuales y operativas del diagnóstico Deterioro del intercambio gaseoso. Métodos Análisis de contenido, realizado por 39 jueces enfermeros, dividido en las fases de definición conceptual del fenómeno de interés, construcción de la estructura del fenómeno de interés y análisis de los jueces sobre la estructura construida. Resultados De los 22 indicadores, 21 fueron considerados relevantes Deterioro del intercambio gaseoso. Los indicadores que obtuvieron relevancia absoluta fueron Cianosis, Hipercapnia, Hipoxemia y Taquicardia. El indicador Cefalea al despertar no mostró relevancia estadísticamente significativa para el diagnóstico. Todas las definiciones conceptuales y operativas fueron claras y precisas. Conclusión Los indicadores enumerados para Deterioro del intercambio gaseoso fueron relevantes para el fenómeno, excepto Cefalea al despertar porque no corresponde a una manifestación segura para identificar el diagnóstico, según el análisis de los jueces. Cada definición conceptual y operativa fue adecuada para su indicador.
https://doi.org/10.1590/1983-1447.2021.20200099
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15.
Insatisfação com o trabalho, aspectos psicossociais, satisfação pessoal e saúde mental de trabalhadores e trabalhadoras da saúde
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Sousa, Camila Carvalho de
; Araújo, Tânia Maria de
; Lua, Iracema
; Gomes, Mariana Rabelo
; Freitas, Kátia Santana
.
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Resumo: O objetivo foi avaliar a relação da insatisfação no trabalho e ocorrência de transtornos mentais comuns (TMC), considerando os aspectos psicossociais do trabalho e a satisfação pessoal (SAP). Estudo transversal, em amostra de 3.084 trabalhadores/as de saúde de cinco municípios baianos. Empregou-se análise de modelagem de equações estruturais, estratificada por gênero. A insatisfação com o trabalho foi a variável de exposição principal. Os TMC, variável desfecho, foram avaliados pelo Self-Reporting Questionaire (SRQ-20). Satisfação pessoal, avaliada por questões do World Health Organization Quality of Life (WHOQOL), e os aspectos psicossociais estressores (AE) e protetores (AP), mensurados pelo Job Content Questionnaire (JCQ) e pela escala Effort-Reward Imbalance (ERI), foram tratadas como variáveis latentes. A insatisfação com o trabalho associou-se positivamente aos TMC, entre homens (0,160; IC95%: 0,024; 0,295) e mulheres (0,198; IC95%: 0,135; 0,260). Os AE associaram-se positivamente à insatisfação com o trabalho e aos TMC, enquanto os AP associaram-se negativamente a esses dois eventos, entre homens e mulheres. A insatisfação com o trabalho mediou o efeito dos aspectos psicossociais e da SAP na ocorrência de TMC. O modelo final apresentou bom ajuste nos grupos analisados. Elevada insatisfação, presença de aspectos psicossociais estressores, carência de aspectos protetores e insatisfação pessoal associaram-se aos TMC direta ou indiretamente. Os resultados reforçam a necessidade de ações voltadas à proteção da saúde mental no trabalho em saúde com o redesenho dos aspectos nocivos identificados e fortalecimento dos aspectos associados à menor ocorrência de TMC.
Abstract: The objective was to evaluate the relationship between job dissatisfaction and the occurrence of common mental disorders (CMD), considering the psychosocial aspects of work and personal satisfaction. Cross-sectional study, with a sample of 3,084 health workers from five municipalities in Bahia. Structural equation modeling analysis, stratified by gender, was used. Dissatisfaction with work was the main exposure variable. The CMD, the outcome variable, was assessed by the Self-Reporting Questionnaire (SRQ-20). Personal satisfaction (SAP), assessed by World Health Organization Quality of Life (WHOQOL) questions, and stressful (AE) and protective (AP) psychosocial aspects, measured by the Job Content Questionnaire (JCQ) and the Effort-Reward Imbalance scale (ERI), were treated as latent variables. Dissatisfaction with work was associated with higher CMD prevalence, among men (0.160; CI95%: 0.024; 0.295) and women (0.198; CI95%: 0.135; 0.260). AEs were associated with greater dissatisfaction and higher CMD prevalence, while APs were associated with lower dissatisfaction and lower CMD prevalence, among men and women. Dissatisfaction with work mediated the effect of psychosocial aspects and personal satisfaction on the occurrence of CMD. The final model showed good adjustment. High job dissatisfaction, stressful psychosocial aspects, lack of protective aspects, and personal dissatisfaction were associated directly or indirectly with CMD. The results reinforce the need for actions to protect mental health at work by redesigning the harmful aspects identified and strengthening the aspects associated with the lower occurrence of CMD.
Resumen: El objetivo fue evaluar la relación de la insatisfacción en el trabajo y la ocurrencia de trastornos mentales comunes (TMC), considerando aspectos psicosociales del trabajo, así como la satisfacción personal. Se trata de un estudio transversal, en una muestra de 3084 trabajadores/as de salud de cinco municipios bahianos. Se utilizó un análisis de modelado de ecuaciones estructurales, estratificado por género. La insatisfacción con el trabajo fue la variable de exposición principal. Los TMC, variable de desenlace, se evaluaron mediante el Self-Reporting Questionaire (SRQ-20). Satisfacción personal (SAP), evaluada por cuestiones del World Health Organization Quality of Life (WHOQOL), y los aspectos psicosociales estresores (AE) y protectores (AP), medidos por el Job Content Questionnaire (JCQ) y por la escala Effort-Reward Imbalance (ERI), fueron tratadas como variables latentes. La insatisfacción con el trabajo se asoció positivamente a los TMC, entre hombres (0,160; IC95%: 0,024; 0,295) y mujeres (0,198; IC95%: 0,135; 0,260). Los AE se asociaron positivamente a la insatisfacción con el trabajo y a los TMC, mientras que los AP se asociaron negativamente a esos dos eventos, entre hombres y mujeres. La insatisfacción con el trabajo medió el efecto de los aspectos psicosociales y de la satisfacción personal en la ocurrencia de TMC. El modelo final presentó un buen ajuste en los grupos analizados. Elevada insatisfacción, presencia de aspectos psicosociales estresores, carencia de aspectos protectores e insatisfacción personal se asociaron a los TMC directa o indirectamente. Los resultados refuerzan la necesidad de acciones dirigidas a la protección de la salud mental en el trabajo en salud, con el rediseño de los aspectos nocivos identificados, así como el fortalecimiento de los aspectos asociados a una menor ocurrencia de TMC.
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