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RESUMO Objetivo: Avaliar a dependência do smartphone e a alteração postural da região cervical em adolescentes. Métodos: Estudo transversal, com 281 adolescentes (15 a 19 anos), que frequentavam da 1ᵃ à 3ᵃ série do ensino médio, realizado entre setembro e outubro de 2019 na cidade de Fortaleza, Ceará, Brasil. A coleta dos dados ocorreu em duas etapas. Na primeira, eles responderam a quatro questionários autoaplicáveis: questionário sociodemográfico, condições de saúde e uso do smartphon e, Questionário Nórdico de Sintomas Musculoesqueléticos (NMQ), Self-Report Questi onnaire (SRQ-20) e o Smartphone A ddiction Inventory (SPAI-BR). Na segunda etapa, foram submetidos a fotogrametria pelo Software de Avaliação Postural (SAPO) e avaliação antropométrica (peso e altura). Para a análise dos dados, foi utilizado o SPSS Statistics versão 23.0. Resultados: Do total, 63,3% (n=178) dos adolescentes apresentaram dependência do smartphone, com o uso de 5,8 horas (±3,5) durante a semana e 8,7 (±4,0) no fim de semana. Ao analisar o alinhamento postural na visão anterior, observou-se redução significativa da inclinação lateral de cabeça ao digitar no smartphon e (p=0,002) comparado à posição anatômica (baseline). Na visão lateral foi constatado aumento da anteriorização de cabeça durante o uso do smartphon e (p<0,05). Houve associação da dependência do smartphone com a anteriorização de cabeça (p<0,05). Conclusões: O uso do smartphone na posição de digitação causa alteração postural na região cervical, destacadamente naqueles que apresentam dependência do dispositivo. Dessa forma, são necessárias medidas de promoção de saúde que alertem os adolescentes sobre os efeitos adversos causados pelo uso prolongado do smartphone. Objetivo Métodos transversal 28 15 (1 1 anos, anos , anos) ᵃ médio 201 Fortaleza Ceará Brasil etapas primeira autoaplicáveis sociodemográfico NMQ, NMQ (NMQ) SelfReport Self Report SRQ20 SRQ 20 (SRQ-20 SPAIBR. SPAIBR SPAI BR . (SPAI-BR) etapa SAPO (SAPO peso altura. altura altura) 230 23 0 23.0 Resultados total 633 63 3 63,3 n=178 n178 n 178 (n=178 58 5 8 5, ±3,5 35 (±3,5 87 7 8, ±4,0 40 4 (±4,0 anterior observouse observou se p=0,002 p0002 p 002 (p=0,002 baseline. baseline (baseline) p<0,05. p005 p<0,05 05 (p<0,05) Conclusões dispositivo forma 2 ( (NMQ SRQ2 (SRQ-2 (SPAI-BR 23. 6 63, n=17 n17 17 (n=17 ±3, (±3, ±4, (±4, p=0,00 p000 00 (p=0,00 (baseline p00 p<0,0 (p<0,05 (SRQ- n=1 n1 (n=1 ±3 (±3 ±4 (±4 p=0,0 (p=0,0 p0 p<0, (p<0,0 (SRQ n= (n= ± (± p=0, (p=0, p<0 (p<0, (n p=0 (p=0 p< (p<0 p= (p= (p< (p

ABSTRACT Objective: To evaluate smartphone addiction and postural alterations in the cervical region in adolescents. Methods: A cross-sectional study with 281 adolescents (15 to 19 years old), attending the 1st to the 3rd grades of High School, carried out between September and October 2019 in the city of Fortaleza, Ceará, Brazil. Data collection took place in two stages. In the first, they answered four self-administered questionnaires: sociodemographic questionnaire, health conditions and smartphone use, Nordic Musculoskeletal Symptom Questionnaire (NMQ), Self-Report Questionnaire (SRQ-20) and the Smartphone Addiction Inventory (SPAI-BR). In the second stage, they were submitted to photogrammetry using the Postural Assessment Software (SAPO) and anthropometric assessment (weight and height). The software SPSS Statistics version 23.0 was used for data analysis. Results: Of the total number of adolescents, 63.3% (n=178) showed smartphone addiction, using it for 5.8 hours (±3.5) during the week and 8.7 (±4.0) hours on the weekend. When analyzing postural alignment in the anterior view, a significant reduction in the lateral head tilt was observed when typing on the smartphone (p=0.002) compared to the anatomical position (baseline). In the lateral view, an increase in head anteriorization was observed during smartphone use (p<0.05). There was an association between smartphone addiction and head anteriorization (p<0.05). Conclusions: The use of the smartphone in the typing position causes postural alterations in the cervical region, especially in adolescents with smartphone addiction. Therefore, health promotion measures that alert adolescents to the adverse effects caused by prolonged smartphone use are necessary. Objective Methods crosssectional cross sectional 28 15 (1 1 old, old , old) st rd School 201 Fortaleza Ceará Brazil stages first selfadministered self administered questionnaires questionnaire NMQ, NMQ (NMQ) SelfReport Self Report SRQ20 SRQ 20 (SRQ-20 SPAIBR. SPAIBR SPAI BR . (SPAI-BR) stage SAPO (SAPO weight height. height height) 230 23 0 23. analysis Results 633 63 3 63.3 n=178 n178 n 178 (n=178 58 5 8 5. ±3.5 35 (±3.5 87 7 8. ±4.0 40 4 (±4.0 weekend view p=0.002 p0002 p 002 (p=0.002 baseline. baseline (baseline) p<0.05. p005 p<0.05 05 (p<0.05) Conclusions Therefore necessary 2 ( (NMQ SRQ2 (SRQ-2 (SPAI-BR 6 63. n=17 n17 17 (n=17 ±3. (±3. ±4. (±4. p=0.00 p000 00 (p=0.00 (baseline p00 p<0.0 (p<0.05 (SRQ- n=1 n1 (n=1 ±3 (±3 ±4 (±4 p=0.0 (p=0.0 p0 p<0. (p<0.0 (SRQ n= (n= ± (± p=0. (p=0. p<0 (p<0. (n p=0 (p=0 p< (p<0 p= (p= (p< (p

https://doi.org/10.1590/1984-0462/2024/42/2023051

Long-term outcomes of intraoperative triamcinolone injection versus postoperative oral prednisolone in congenital cataract surgery Longterm Long term
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Ventura, Bruna Vieira

; Ribeiro, Mariana Zaira

; Caldas, Nayara Rayanne Bezerra

; Ventura, Larissa

; Marinho, Polyana

; Lira, Rodrigo Pessoa Cavalcanti

; Rocha, Camilla Silva da

; Ventura, Marcelo Carvalho

Arquivos Brasileiros de Oftalmologia

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2024, Volume 87 N. 3 elocation e2021-0514

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Objetivo: Comparar os achados oculares em longo prazo de crianças que se submeteram à cirurgia de catarata congênita antes dos dois anos de idade e receberam uma injeção intracameral de triancinolona no intraoperatório ou usaram prednisolona oral no pós-operatório para modular a inflamação ocular. Métodos: Neste estudo prospectivo de coorte, todos os pacientes que participaram de um ensaio clínico anterior, que analisou os resultados cirúrgicos de 1 ano da cirurgia de catarata congênita usando triancinolona intracameral (Grupo de Estudo) ou prednisolona oral (Grupo Controle), eram elegíveis para participar. Os prontuários médicos dos pacientes foram revisados e as crianças foram submetidas a um exame oftalmológico completo no acompanhamento final. As principais medidas de desfecho foram: achados biomicroscópicos, pressão intraocular, espessura central da córnea, a necessidade de intervenções cirúrgicas adicionais e achados compatíveis com glaucoma. Resultados: Vinte e seis olhos (26 pacientes) foram incluídos (Grupo de Estudo = 11 olhos; Grupo de Controle = 15 olhos). O seguimento médio foi de 8,2 ± 1,2 anos e 8,1 ± 1,7 anos nos Grupos de Estudo e Controle, respectivamente (p=0,82). Todos os olhos apresentavam lente intraocular centrada. Não houve diferença estatisticamente significativa entre os grupos com relação à presença de sinéquia posterior (p=0,56), pressão intraocular (p=0,49) ou espessura central da córnea (p=0,21). Nenhum dos olhos preencheu os critérios diagnósticos para glaucoma, apresentou opacificação secundária do eixo visual ou foi reoperado. Conclusão: Os achados oculares em longo prazo de crianças que se submeteram à cirurgia de catarata congênita e receberam uma injeção intracameral de triancinolona no intraoperatório foram semelhantes aos que usaram prednisolona oral no pós-operatório para modular a inflamação ocular, sugerindo que a triancinolona intracameral pode substituir a prednisolona oral na cirurgia de catarata congênita, facilitando o tratamento pós-operatório e a adesão ao mesmo. Objetivo pósoperatório pós operatório ocular Métodos coorte anterior , Controle) participar final biomicroscópicos glaucoma Resultados 26 (2 olhos. . olhos) 82 8 2 8, 12 1, 81 17 7 p=0,82. p082 p p=0,82 0 (p=0,82) centrada p=0,56, p056 p=0,56 56 (p=0,56) p=0,49 p049 49 (p=0,49 p=0,21. p021 p=0,21 21 (p=0,21) reoperado Conclusão mesmo ( p08 p=0,8 (p=0,82 p05 p=0,5 5 (p=0,56 p=0,4 p04 4 (p=0,4 p02 p=0,2 (p=0,21 p0 p=0, (p=0,8 (p=0,5 (p=0, (p=0,2 p=0 (p=0 p= (p= (p

ABSTRACT Purpose: To compare the long-term ocular findings of children that were operated of congenital cataract before the age of two and that received an intraoperative intracameral triamcinolone injection or used postoperative oral prednisolone to modulate ocular inflammation. Methods: All patients who had previously participated in a clinical trial that analyzed the 1-year surgical outcomes of congenital cataract surgery utilizing intracameral triamcinolone (study group) or oral prednisolone (control group) were eligible to participate in this prospective cohort research. Patients’ medical records were reviewed, and the children underwent a complete ophthalmologic exam on final follow-up. Biomicroscopic findings, intraocular pressure, central corneal thickness, the need for additional surgical interventions, and findings compatible with glaucoma were the primary end measures. Results: Twenty-six eyes (26 patients) were included (study group = 11 eyes; control group = 15 eyes). The mean follow--up was 8.2 ± 1.2 years and 8.1 ± 1.7 years in the study and control groups, respectively (p=0.82). All eyes presented a centered intraocular lens. There was no statistically significant difference between the groups with regards to the presence of posterior synechia (p=0.56), intraocular pressure (p=0.49), or central corneal thickness (p=0.21). None of the eyes fulfilled the glaucoma diagnostic criteria, presented secondary visual axis obscuration, or were reoperated. Conclusion: The long--term ocular findings of children that underwent congenital cataract surgery and received an intraoperative intracameral triamcinolone injection were similar to those that used postoperative oral prednisolone to modulate ocular inflammation. This suggests that intracameral triamcinolone may substitute oral prednisolone in congenital cataract surgery, facilitating the postoperative treatment regimen and compliance. Purpose longterm long term inflammation Methods 1year year 1 research Patients reviewed followup. followup follow up. up follow-up interventions measures Results Twentysix Twenty six 26 (2 eyes. . eyes) 82 8 2 8. 12 1. 81 17 7 p=0.82. p082 p p=0.82 0 (p=0.82) lens p=0.56, p056 p=0.56 , 56 (p=0.56) p=0.49, p049 p=0.49 49 (p=0.49) p=0.21. p021 p=0.21 21 (p=0.21) criteria obscuration reoperated Conclusion compliance ( p08 p=0.8 (p=0.82 p05 p=0.5 5 (p=0.56 p04 p=0.4 4 (p=0.49 p02 p=0.2 (p=0.21 p0 p=0. (p=0.8 (p=0.5 (p=0.4 (p=0.2 p=0 (p=0. p= (p=0 (p= (p

https://doi.org/10.5935/0004-2749.2021-0514

Decay of pathogens (indicators of Escherichia coli and Salmonella spp.) in soil due to the application of reuse water indicators spp. spp
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Handam, Natasha Berendonk

; Silva, Rodrigo Bezerra da

; Carvajal, Elvira

; Sotero-Martins, Adriana

Revista Ambiente & Água

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2024, Volume 19 elocation e2950

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo A água de reúso é definida como a reutilização de águas provenientes de efluentes tratados, e requer segurança sanitária para evitar danos à saúde ambiental. O objetivo foi avaliar o decaimento de bactérias (Escherichia coli e Salmonella spp.) em solo irrigado com água de reúso, visando o reúso agrícola sem causar danos à saúde pública e ambiental.O decaimento de Escherichia coli foi verificado utilizando o método de Membrana Filtrante, e o de Salmonella spp. foi utilizado o meio de cultura SS AGAR. As curvas de decaimento ao longo do tempo foram feitas pelo programa Sigmaplot. Cada grupo experimental tinha 4 vasos (grupo irrigado com água de reúso e outro com água potável) sendo dois vasos contendo cobertura vegetal e dois contendo apenas solo. Nos cultivos irrigados com água de reúso, o tempo de sobrevivência de Salmonella spp. foi o dobro em comparação aos demais, e a sobrevivência da Escherichia coli não variou entre os grupos. Os vasos com solo nu irrigados com água de reúso sem contaminação mostraram um decaimento da Salmonella spp. mais rápido. Para o reúso agrícola a rega deve ser por gotejamento e com a utilização de equipamentos de proteção individual. É fundamental a criação de legislação nacional, prevenindo danos à saúde pública e ambiental. tratados ambiental spp ambientalO Filtrante AGAR Sigmaplot potável demais grupos rápido individual nacional

Abstract Reuse water is defined as the reuse of water from treated effluents, it requires careful monitoring to avoid damage to environmental health. This study evaluates the decay of Escherichia coli and Salmonella spp. bacteria in soil irrigated with reused water for agricultural reuse, without damaging public or environmental health. The decay of Escherichia coli and of Salmonella spp. was verified using the Filter Membrane method SS AGAR culture medium was used. The decay curves over time were made using the Sigmaplot program. Each experimental group had 4 pots (one group irrigated with recycled water and the other with drinking water), two pots containing vegetation cover and two containing only soil. In crops irrigated with reused water, the survival time of Salmonella spp. was double compared to the others, and E. coli survival did not vary between groups. Pots with bare soil irrigated with uncontaminated reused water showed a faster decline in Salmonella spp. For agricultural reuse, irrigation must be done by drip and with the use of personal protective equipment. It is essential to create national legislation to protect public and environmental health. effluents health spp used program one , water) others E groups equipment

https://doi.org/10.4136/ambi-agua.2950

Estratégias educativas em saúde para pessoas vivendo com HIV: revisão de escopo HIV
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Duarte, Fernando Hiago da Silva

; Silva, Silmara de Oliveira

; Oliveira, Eloysa dos Santos

; Silva, Bruna Vilar Soares da

; Melo, Evelin Beatriz Bezerra de

; Cabral, Maria Amélia Lopes

; Dantas, Rodrigo Assis Neves

; Dantas, Daniele Vieira

Acta Paulista de Enfermagem

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2024, Volume 37 elocation eAPE02572

Abstract: Pt En Es | Text: Pt En Es | PDF: Pt | PDF: En | PDF: Es

Resumo Objetivo Mapear a produção científica sobre as estratégias educativas e os conteúdos abordados na educação de pessoas vivendo com HIV. Métodos Esta é uma revisão de escopo em que a seleção dos artigos foi realizada em abril de 2021 e atualizada em outubro de 2022 em dez fontes de dados; a revisão seguiu os pressupostos estabelecidos pelo Joanna Briggs Institute e o checklist dos Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for Scoping Reviews. Os resultados foram analisados descritivamente e sintetizados em um quadro. Resultados Foram selecionados 17 estudos com publicação predominante em 2017; Estados Unidos da América e Brasil foram os países com a maior quantidade de produções. A maioria dos estudos buscou avaliar o impacto e a eficácia das estratégias e desenvolver ou validar instrumentos de educação em saúde e atividades de prevenção. Em relação ao conteúdo abordado pelas estratégias, foram formadas cinco categorias: orientação inicial sobre HIV/AIDS, cuidados gerais, vida saudável, saúde sexual e suporte emocional. As estratégias educativas que se destacaram em relação à maior adesão dos pacientes ao tratamento estão relacionadas com o desenvolvimento de sistemas, programas e multimídia. As cartilhas promoveram empoderamento e autonomia de pessoas vivendo com HIV. Conclusão Foram mapeadas as principais estratégias educativas, com destaque para cartilhas, material impresso, recursos multimídia, sistemas, formulários e oficinas/workshops, abordando orientação inicial sobre HIV/AIDS, tratamento farmacológico, cuidados gerais, vida saudável, saúde sexual e suportes social e emocional. HIV 202 dados MetaAnalyses Meta Analyses Reviews quadro 1 2017 produções prevenção categorias HIVAIDS AIDS HIV/AIDS gerais saudável emocional sistemas multimídia impresso oficinasworkshops oficinas workshops oficinas/workshops farmacológico 20 201 2

Abstract Objective To map the scientific production on educational strategies and the content covered in the education of people living with HIV. Methods This is a scoping review in which the selection of articles was carried out in April 2021 and updated in October 2022 in ten data sources; the review followed the assumptions established by the Joanna Briggs Institute and the checklist of Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for Scoping Reviews. The results were descriptively analyzed and summarized in a chart. Results A total of 17 studies were selected, predominantly published in 2017; The USA and Brazil were the countries with the largest number of productions. Most studies sought to evaluate the impact and effectiveness of strategies and develop or validate health education instruments and prevention activities. Concerning the content covered by the strategies, five categories were formed: initial guidance on HIV/AIDS, general care, healthy living, sexual health, and emotional support. The educational strategies that stood out concerning greater patient adherence to treatment are related to the development of systems, programs, and multimedia. The booklets promoted empowerment and autonomy for people living with HIV. Conclusion The main educational strategies were mapped, with emphasis on booklets, printed material, multimedia resources, systems, forms, and workshops, covering initial guidance on HIV/AIDS, pharmacological treatment, general care, healthy living, sexual health, and social and emotional support. Open Science Framework (OSF): https://osf.io/754uk/?view_only=6491865a3d12424d81af2c4099c112c3 HIV 202 sources MetaAnalyses Meta Analyses Reviews chart 1 selected 2017 productions activities formed HIVAIDS AIDS HIV/AIDS care support systems programs mapped material resources forms workshops OSF (OSF) https//osf.io/754uk/view_only=6491865a3d12424d81af2c4099c112c3 httpsosfio754ukviewonly6491865a3d12424d81af2c4099c112c3 httpsosfioukviewonlyaddafccc https //osf.io/754uk/ view_only=6491865a3d12424d81af2c4099c112c3 osf io 754uk view only 6491865a3d12424d81af2c4099c112c3 uk d af c https://osf.io/754uk/?view_only=6491865a3d12424d81af2c4099c112c 20 201 (OSF https//osf.io/754uk/view_only=6491865a3d12424d81af2c4099c112c httpsosfio ukviewonly httpsosfio754ukviewonly6491865a3d12424d81af2c4099c112c osfio754uk osfiouk //osf.io/754uk viewonly6491865a3d12424d81af2c4099c112c3 viewonlyaddafccc view_only=6491865a3d12424d81af2c4099c112c addafccc 6491865a3d12424d81af2c4099c112c 2 osfio viewonly viewonly6491865a3d12424d81af2c4099c112c

Resumen Objetivo Mapear la producción científica sobre las estrategias educativas y los contenidos abordados en la educación de personas que viven con el VIH. Métodos Esta es una revisión de alcance, cuya selección de artículos se realizó en abril de 2021 y se actualizó en octubre de 2022 en diez fuentes de datos. La revisión siguió las premisas establecidas por el Joanna Briggs Institute y la checklist de los Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for Scoping Reviews. Los resultados fueron analizados descriptivamente y sintetizados en un cuadro. Resultados Se seleccionaron 17 estudios con publicación predominante en 2017. Estados Unidos de América y Brasil fueron los países con mayor cantidad de producciones. La mayoría de los estudios buscó evaluar el impacto y la eficacia de las estrategias y elaborar o validar instrumentos de educación para la salud y actividades de prevención. Con relación al contenido abordado por las estrategias, se formaron cinco categorías: instrucciones iniciales sobre VIH/SIDA, cuidados generales, vida saludable, salud sexual y apoyo emocional. Las estrategias educativas que se destacaron con relación a una mayor adhesión de los pacientes al tratamiento están relacionadas con el desarrollo de sistemas, programas y multimedia. Las cartillas promovieron empoderamiento y autonomía de personas que viven con el VIH. Conclusión Se mapearon las principales estrategias educativas, con énfasis en cartillas, material impreso, recursos multimedia, sistemas, formularios y talleres/workshops, que abordaron instrucciones iniciales sobre VIH/SIDA, tratamiento farmacológico, cuidados generales, vida saludable, salud sexual y apoyo social y emocional. Open Science Framework (OSF): https://osf.io/754uk/?view_only=6491865a3d12424d81af2c4099c112c3 VIH alcance 202 datos MetaAnalyses Meta Analyses Reviews cuadro 1 2017 producciones prevención categorías VIHSIDA SIDA VIH/SIDA generales saludable emocional sistemas multimedia impreso talleresworkshops talleres workshops talleres/workshops farmacológico OSF (OSF) https//osf.io/754uk/view_only=6491865a3d12424d81af2c4099c112c3 httpsosfio754ukviewonly6491865a3d12424d81af2c4099c112c3 httpsosfioukviewonlyaddafccc https //osf.io/754uk/ view_only=6491865a3d12424d81af2c4099c112c3 osf io 754uk view only 6491865a3d12424d81af2c4099c112c3 uk d af c https://osf.io/754uk/?view_only=6491865a3d12424d81af2c4099c112c 20 201 (OSF https//osf.io/754uk/view_only=6491865a3d12424d81af2c4099c112c httpsosfio ukviewonly httpsosfio754ukviewonly6491865a3d12424d81af2c4099c112c osfio754uk osfiouk //osf.io/754uk viewonly6491865a3d12424d81af2c4099c112c3 viewonlyaddafccc view_only=6491865a3d12424d81af2c4099c112c addafccc 6491865a3d12424d81af2c4099c112c 2 osfio viewonly viewonly6491865a3d12424d81af2c4099c112c

https://doi.org/10.37689/acta-ape/2024ar002572

Detached epithelial cell plugs from the upper respiratory tract favour distal lung injury in Golden Syrian hamsters (Mesocricetus auratus) when experimentally infected with the A.2 Brazilian SARS-CoV-2 strain Mesocricetus auratus A2 A 2 A. SARSCoV2 SARSCoV SARS CoV SARS-CoV- SARS-CoV
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Pelajo-Machado, Marcelo

; da Silva, Alexandre dos Santos

; Rodrigues, Daniela del Rosario Flores

; Paiva, Milla Bezerra

; Muller, Rodrigo

; da Costa, Luciana Jesus

; Manso, Pedro Paulo Abreu

; dos Santos, João Paulo Rodrigues

; da Silva, Emanuelle de Souza Ramalho Ferreira

; Alves, Arthur Daniel Rocha

; Oliveira, Jaqueline Mendes

; Pinto, Marcelo Alves

Memórias do Instituto Oswaldo Cruz

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2024, Volume 119 elocation e240100

Abstract: En | Text: En | PDF: En

BACKGROUND The Golden Syrian hamster (Mesocricetus auratus), Ferrets (Mustela putorius furo), and macaques have been described as useful laboratory animals naturally susceptible to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. OBJECTIVES To study the mechanism of lung injury, we describe the histopathological features of SARS-CoV-2 infection in Golden Syrian hamsters inoculated intranasally with the A.2 Brazilian strain. METHODS Hamsters were intranasally inoculated with the A.2 variant and euthanised at 3-, 5-, 10- and 15-days post-inoculation. The physical examination and body weight were recorded daily. Neutralising antibodies and viral RNA load of the respiratory tract were assessed during necropsies. FINDINGS The coronavirus disease 2019 (COVID-19) model presented body weight loss, high levels of respiratory viral RNA load, severe segmentary pneumonitis, and bronchial fistula besides lymphatic trapping and infiltration, like the human SARS-COV-2 pathogenesis. The presence of subepithelial lymphoeosinophilic infiltrate was highlighted in our results; it contributed to the detachment of SARS-CoV-2 nucleocapsid-positive epithelial cells resulting in the infectious cell plugs. MAIN CONCLUSIONS The SARS-CoV-2 caused segmentary pneumonia and vascular damage. In our comprehension, the infectious cell plugs, as being aspirated from the upper respiratory tract into the terminal bronchial lumen, work as a “Trojan horse”, thus contributing to the dissemination of the SARS-CoV-2 infection into specific regions of the deep lung parenchyma. Mesocricetus auratus, auratus , auratus) Mustela furo, furo furo) SARSCoV2 SARSCoV SARS CoV (SARS-CoV-2 injury SARS-CoV- A2 A A. strain 3, 3 3- 5, 5 5- 10 15days days 15 postinoculation. postinoculation post inoculation. inoculation post-inoculation daily necropsies 201 COVID19 COVID 19 (COVID-19 loss pneumonitis infiltration SARSCOV2 SARSCOV COV SARS-COV- pathogenesis results nucleocapsidpositive nucleocapsid positive plugs damage comprehension lumen Trojan horse, horse horse” parenchyma (SARS-CoV- SARS-CoV 1 20 COVID1 (COVID-1 SARS-COV (SARS-CoV (COVID- (COVID

https://doi.org/10.1590/0074-02760240100

Exhaled air profile in the early diagnosis of ventilator-associated pneumonia ventilatorassociated ventilator associated
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Figueiredo, Rodrigo Cruvinel

; Silva, Jackelyne Lopes

; Bianchini, Igor

; Rocha, Luana Bezerra Gonçalves

; Goncalves, Renata Casagrande

; Ritter, Cristiane

; Dal-Pizzol, Felipe

Critical Care Science

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2024, Volume 36 elocation e20240194en

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Objetivo Demonstrar a predição do ar exalado dos pacientes submetidos à ventilação mecânica no diagnóstico à beira leito da pneumonia associada à ventilação mecânica. Métodos Foram coletadas amostras de ar através do ramo expiratório do circuito de ventilação mecânica ao longo da internação de pacientes na unidade de terapia intensiva do Hospital São José, em Criciúma (SC). O trabalho analisou 83 participantes subdivididos em dois grupos, com e sem pneumonia associada à ventilação mecânica. Resultados Por meio da análise de três padrões de ar identificados, conseguiu-se um valor preditivo para diagnóstico de pneumonia associada à ventilação mecânica. As análises das amostras das primeiras 12 horas de ventilação mecânica invasiva foram capazes de predizer a pneumonia associada à ventilação mecânica (p = 0,018). Entretanto, nenhuma das outras amostras de ar coletadas ao longo da internação dos pacientes foi capaz de caracterizar gravidade ou predizer, em precoce ou tardia, a pneumonia associada à ventilação mecânica. Conclusão A utilização de um aparelho analisador de gases pode ser útil na identificação precoce dos pacientes que desenvolverão pneumonia associada à ventilação mecânica internados em terapia intensiva. José SC. SC . (SC) 8 grupos identificados conseguiuse conseguiu se 1 p 0,018. 0018 0,018 0 018 0,018) Entretanto tardia (SC 001 0,01 01 00 0,0 0,

ABSTRACT Objective To predict exhaled air in patients undergoing mechanical ventilation during bedside diagnosis of ventilator-associated pneumonia. Methods Air samples were collected through the expiratory branch of the mechanical ventilation circuit during the hospitalization of patients at the intensive care unit of Hospital São José in Criciúma (SC), Brazil. In this study, 83 participants were divided into two groups, namely, the group with and the group without ventilator-associated pneumonia. Results The analysis of three air patterns revealed a predictive value for the diagnosis of ventilator-associated pneumonia. The analyses of samples from the first 12 hours of invasive mechanical ventilation were able to predict ventilator-associated pneumonia (p = 0.018). However, none of the other air samples collected during hospitalization were useful in identifying the severity or predicting early or late ventilator-associated pneumonia. Conclusion The use of a gas analyzer may be helpful for the early identification of patients admitted to intensive care who will develop ventilator-associated pneumonia. ventilatorassociated ventilator associated SC, SC , (SC) Brazil study 8 groups namely 1 p 0.018. 0018 0.018 . 0 018 0.018) However (SC 001 0.01 01 00 0.0 0.

https://doi.org/10.62675/2965-2774.20240194-en

Contribuições dos jogos eletrônicos na formação de professores de educação física
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Nunes, Rodrigo Tavares

; Costa, Alan Queiroz da

; Silva, Ana Paula da

; Silva, Pedro Henrique Bezerra da

; Tavares, Marcelo Soares

Revista Brasileira de Ciências do Esporte

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2024, Volume 46 elocation e20230091

Abstract: Pt En Es | Text: Pt En Es | PDF: Pt | PDF: En | PDF: Es

RESUMO O objetivo desta pesquisa foi analisar as contribuições teórico-metodológicas dos jogos eletrônicos na formação de professores em um curso de Licenciatura em Educação Física. Optamos por uma abordagem qualitativa e pela Hermenêutica-Dialética como método, cujo princípio central é a comunicação, abordada nesta pesquisa por meio de uma entrevista semiestruturada com os professores na formação inicial em Educação Física em uma universidade pública. Concluímos que os jogos eletrônicos trazem contribuições teórico-metodológicas para a formação de professores de Educação Física. Eles estão presentes na vida dos estudantes como também nos cursos de formação inicial. Revelamos, nesta pesquisa, possibilidades de trabalho com esses jogos na prática pedagógica dos professores. teóricometodológicas teórico metodológicas HermenêuticaDialética Hermenêutica Dialética método comunicação pública Revelamos

ABSTRACT The purpose of this research was to analyze the theoretical-methodological contributions of video games to teachers training in a Physical Education degree program. We opted for a qualitative approach and employed Hermeneutic-Dialectical methodology, whose central principle is communication, explored in this research through semi-structured interviews with teachers in Physical Education training at a public university. We concluded that video games provide theoretical-methodological contributions to the training of Physical Education teachers. They are present in the students' lives and also in degree programs. We revealed in this research possibilities for working with these games in the teaching practice. theoreticalmethodological theoretical methodological program HermeneuticDialectical Hermeneutic Dialectical methodology communication semistructured semi structured university students programs practice

RESUMEN El objetivo de esta investigación fue analizar los aportes teórico-metodológicas de los videojuegos en la formación de docentes en un curso de licenciatura en Educación Física. Optamos por un enfoque cualitativo y por la Hermenéutica-Dialéctica como método, cuyo principio central es la comunicación, abordada en esta investigación a través de una entrevista con los profesores del curso de Educación Física de una universidad pública. Concluimos que los videojuegos aportan contribuciones teórico-metodológicas a la formación de profesores de Educación Física. Están presentes en la vida de los estudiantes y también en los cursos de Educación Física. En esta investigación, revelamos posibilidades de trabajo con estos juegos en la práctica pedagógica de los profesores. teóricometodológicas teórico metodológicas HermenéuticaDialéctica Hermenéutica Dialéctica método comunicación pública

https://doi.org/10.1590/rbce.46.e20230091

Effects of water immersion on cardiac responses in people living with HIV at rest and during exercise
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Masi, Fabrízio Di

; Silva, Gabriel Costa e

; Silveira, Anderson Luiz Bezerra da

; Conceição, Rodrigo Rodrigues da

; Ribeiro, Luiz Claudio Pereira

; Ferry, Fernando Raphael de Almeida

Motricidade

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sep 2023, Volume 19 N. 3 Pages 289 - 296

Abstract: En | Text: En | PDF: En

ABSTRACT The present research aimed to compare the HRV of people living with HIV (PLWH) with non-infected individuals in aquatic and dryland environments. Twenty participants were divided into two groups. PLWH composed the experimental group (EG), and seronegative participants composed the control group (CG). In dryland, HRV was measured in time and frequency domains, as follows: 10 minutes in rest (RES), 20 minutes of moderate and intense aerobic exercise (EXE), and 30 minutes post-exercise recovery (REC). After 72 hours, the same procedures were repeated in the aquatic environment. HRV analysis demonstrated significant differences in Mean r-r (Δ%= 3.5%, p< 0.01) and rMSSD (Δ%= −19.4%, p< 0.05) when compared dryland vs aquatic environment in RES. We observed similar results in rMSSD (Δ%= 49.2%, p< 0.01), pNN50(%) (Δ%= 79.1%, p< 0.01), and SD1 (Δ%= 49.3%, p< 0.01), during REC. Significant differences (p< 0.01) were also demonstrated for the HF during RES (Δ%= −43.4%) and REC (Δ%= −28.8%). However, the EG intra-group analysis showed no significant differences. The inter-group analysis at RES in dryland demonstrated significant differences in rMSSD (Δ%= −36.5%, p< 0.05), pNN50(%) (Δ%= −54.8%, p< 0.05), and SD1 (Δ%= 46.5%, p< 0.05). We also observed significant differences in mean R-R intervals (Δ%= −17.8%, p< 0.01), SDNN (Δ%= −41.2%, p< 0.01), rMSSD (Δ%= −50.5%, p< 0.01), pNN50 (Δ%= −73.6%, p< 0.001), and SD1 (Δ%= −50.4%, p< 0.001) during water immersion as well as the HF (Δ%= −67.6%, p< 0.01). The mean R-R interval (Δ%= −16.3%, p< 0.01), SDNN (Δ%= −46.4%, p< 0.001), rMSSD (Δ%= −57.0%, p< 0.001), pNN50 (Δ%= −73.1, p< 0.001), and SD1 (Δ%= −57.1, p< 0.001) also showed significant differences during REC. Water immersion increases the CG vagal modulation as expected. However, without any influence in EG. The results indicate a decreased vagal modulation in PLHIV in ART, indicating a possible autonomic dysfunction over the heart for this group.

https://doi.org/10.6063/motricidade.31530

Papel da imagem na indicação da eletroporação irreversível no manejo terapêutico do adenocarcinoma de pâncreas
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Silva, Thiago Pereira Fernandes da

; Moreno, Raquel Andrade

; Polizio, Rodrigo Pamplona

; Melo, Rayssa Araruna Bezerra de

; Macedo, Antônio Luiz de Vasconcelos

; Brito, Luiz Tenório Siqueira de

Radiologia Brasileira

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feb 2023, Volume 56 N. 1 Pages 42 - 49

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo O adenocarcinoma ductal de pâncreas é uma das neoplasias malignas mais agressivas, com taxas de sobrevivência anuais inferiores a 20%. Os métodos axiais (tomografia computadorizada e ressonância magnética) têm papel fundamental no diagnóstico e estadiamento da doença, por fornecerem adequada resolução anatômica na avaliação de estruturas-chave, principalmente vasculares. O adenocarcinoma ductal de pâncreas é frequentemente descoberto em estágios avançados e sem viabilidade de ressecção cirúrgica, e nesse cenário o desenvolvimento de alternativas terapêuticas minimamente invasivas tem sido ainda mais importante para a mudança de sua história natural. A eletroporação irreversível, procedimento intervencionista que minimiza efeitos deletérios nos tecidos adjacentes, vem se destacando no tratamento de lesões tradicionalmente consideradas irressecáveis. Essa técnica, apesar de ganhar cada vez mais espaço no manejo terapêutico do adenocarcinoma ductal de pâncreas, ainda é pouco familiar aos radiologistas. Neste estudo, buscamos expor, de forma sucinta e didática, os fundamentos da técnica, as principais características de imagem e os critérios de elegibilidade que devem ser considerados para indicação da eletroporação irreversível nessa doença. agressivas 20 20% tomografia magnética doença estruturaschave, estruturaschave estruturas chave, chave estruturas-chave vasculares cirúrgica natural adjacentes irressecáveis técnica radiologistas estudo expor didática 2

Abstract Pancreatic ductal adenocarcinoma is one of the most aggressive malignant neoplasms, with a one-year survival rate below 20%. Axial methods (computed tomography and magnetic resonance imaging) play a fundamental role in the diagnosis and staging of the disease, because they provide adequate anatomical resolution in the assessment of key structures, mainly vascular structures. Pancreatic ductal adenocarcinoma is most often discovered in advanced stages, when surgical resection is no longer feasible. In that scenario, minimally invasive treatment alternatives have been developed in attempts to change the natural history of the disease. Irreversible electroporation, an interventional procedure that minimizes deleterious effects on adjacent tissues, has proven useful for the treatment of tumors traditionally considered unresectable. Despite the growing acknowledgment of this technique as a tool for the management of pancreatic ductal adenocarcinoma, it is still relatively unknown among radiologists. In this study, we sought to provide an overview of the main characteristics and eligibility criteria that must be considered for the indication of irreversible electroporation in cases of pancreatic ductal adenocarcinoma. neoplasms oneyear year 20 20% computed imaging disease structures stages feasible scenario tissues unresectable radiologists study 2

https://doi.org/10.1590/0100-3984.2022.0032

10.

Blood parasite load by qPCR as therapeutic monitoring in visceral leishmaniasis patients in Brazil: a case series study Brazil
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Aquino, Samuel Ricarte de

; Diniz, Lucyo Flávio Bezerra

; Nunes, Sávio Luiz Pereira

; Silva, Roberta Lane de Oliveira

; Gouveia, Gisele Veneroni

; Gouveia, João José Simoni

; Sales, Kamila Gaudêncio da Silva

; Dantas-Torres, Filipe

; Carmo, Rodrigo Feliciano do

Revista da Sociedade Brasileira de Medicina Tropical

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2023, Volume 56 elocation e0456-2022

Abstract: En | Text: En | PDF: En

ABSTRACT Background: This study aimed to describe the kinetics of Leishmania parasite load determined using kinetoplast DNA (kDNA)-based quantitative polymerase chain reaction (qPCR) in visceral leishmaniasis (VL) patients. Methods: Parasite load in blood was assessed by qPCR at five time points, up to 12 months post-diagnosis. Sixteen patients were followed up. Results: A significant reduction in the parasite load was observed after treatment (P < 0.0001). One patient had an increased parasite load 3 months post-treatment and relapsed clinically at month six. Conclusions: We have described the use of kDNA-based qPCR in the post-treatment follow-up of VL cases. Background kDNAbased kDNA based (qPCR (VL Methods points 1 postdiagnosis. postdiagnosis post diagnosis. diagnosis post-diagnosis Results P 0.0001. 00001 0.0001 . 0 0001 0.0001) posttreatment six Conclusions followup follow cases 0000 0.000 000 0.00 00 0.0 0.

https://doi.org/10.1590/0037-8682-0456-2022

11.

Impact of land use on the chemical attributes of the soil, Cruzeiro do Sul, in the Brazilian Amazon soil Sul
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Camara, Rodrigo

; Silva, Luciélio Manoel

; Frade Junior, Elizio Ferreira

; Mattar, Eduardo Pacca Luna

; Silva, Sandra Bezerra da

; Silva Neto, Eduardo Carvalho da

; Pereira, Marcos Gervasio

Revista Ciência Agronômica

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2023, Volume 54 elocation e20228450

Abstract: En | Text: En | PDF: En

ABSTRACT Vast areas of the Brazilian Amazon have been deforested for the expansion of livestock and the agricultural frontier, which has resulted in soil exhaustion. It is therefore urgent to reduce deforestation and encourage sustainable land use to promote social and economic development in the region. The aim of this study was to evaluate the impact of different land use systems (an agroforestry system, cassava cultivation, non-degraded pasture, native forest) on the chemical properties of the soil (0-40 cm) in the mesoregion of the Juruá Valley, in the state of Acre, Brazil. Principal component analysis showed the soil in the forested area (reference) has greater values for P, Ca2+, Mg2+, K+, Na+, sum of bases, and cation exchange capacity; while hierarchical cluster analysis suggested little dissimilarity to the soil in the agroforestry system, and high dissimilarity to the soil in the areas of cassava cultivation and pasture. The results therefore support agroforestry as the most sustainable land use system, compared to cassava cultivation or pasture. frontier exhaustion region an system nondegraded non degraded pasture forest 040 0 40 (0-4 cm Valley Acre Brazil reference (reference P Ca2 Ca Ca2+ Mg2 Mg Mg2+ K K+ Na Na+ bases capacity 04 4 (0- (0 (

https://doi.org/10.5935/1806-6690.20230058

12.

Epidemiological study of penile cancer in a northeastern state - Brazil
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Silva, Thais Cristina Loyola da

; Ximenes, Érika Gabrielle Pinheiro

; Santos, Ythalo Hugo da Silva

; Araújo, Rodrigo Jerônimo

; Macedo, Eurides Araújo Bezerra de

; Medeiros, Kleyton Santos de

; Araújo-Filho, Irami

Revista do Colégio Brasileiro de Cirurgiões

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2023, Volume 50 elocation e20233586

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Objetivo: traçar o perfil clínico e epidemiológico do câncer de pênis no Rio Grande do Norte/Brazil e relacioná-los com dados publicados na literatura. Métodos: realizou-se estudo transversal de 94 pacientes diagnosticados com câncer de pênis no período de 2011-2018, tratados na Liga Norte Riograndense Contra o Câncer. Resultados: todos os pacientes foram diagnosticados com carcinoma espinocelular, principalmente com idade acima dos 50 anos, provenientes do interior do estado, pardos, analfabetos ou com ensino fundamental incompleto. Ao diagnóstico, 68% dos pacientes foram classificados com tumores =T2 e 30% possuiam envolvimento linfonodal. Metástases à distância foram detectadas em 2,1% dos pacientes ao diagnóstico. A maioria dos pacientes recebeu o diagnóstico na fase inicial da doença, mas 20,2% foram diagnosticados em estádio IV. Penectomia parcial foi a cirurgia mais realizada e 10% dos pacientes recidivaram, principalmente para linfonodos (87,5%). A média de seguimento dos pacientes foi de 18 meses, apresentando estimativa de sobrevida global em 5 anos de 59,1%. No entanto, 25% dos pacientes foram acompanhados por até 3 meses, perdendo o seguimento. Conclusão: o Estado do Rio Grande do Norte apresenta elevada incidência de câncer de pênis com alta frequência de tumores localmente avançados ao diagnóstico, assim como em pacientes mais jovens, menores que 50 anos de idade. Outrossim, o fator socioeconômico interfere no diagnóstico precoce e dificulta o acesso a serviços especializados. . Objetivo NorteBrazil Brazil relacionálos relacioná los literatura Métodos realizouse realizou se 9 20112018, 20112018 2011 2018, 2018 2011-2018 Câncer Resultados espinocelular estado pardos incompleto 68 T2 T =T 30 linfonodal 21 2 1 2,1 doença 202 20 20,2 IV 10 recidivaram 87,5%. 875 87,5% 87 (87,5%) meses 591 59 59,1% entanto 25 Conclusão jovens Outrossim especializados 2011201 201 2011-201 6 2, 20, 87,5 8 (87,5% 59,1 201120 2011-20 87, (87,5 59, 20112 2011-2 (87, 2011- (87 (8 (

ABSTRACT Objective: to trace the clinical and epidemiological profile of penile cancer in Rio Grande do Norte/Brazil and relate them to data published in the literature. Methods: a cross-sectional study was conducted with 94 patients diagnosed with penile cancer in 2011-2018, treated at the Liga Norte Riograndense Contra o Cancer. Results: all patients were diagnosed with squamous cell carcinoma, mainly aged over 50 years, from the states interior, brown, illiterate, or with incomplete primary education. At diagnosis, 68% of patients were classified as having tumors =T2, and 30% had lymph node involvement. Distant metastases were detected in 2.1% of patients at diagnosis. Most patients received the diagnosis in the initial phase of the disease, but 20.2% were diagnosed in stage IV. Partial penectomy was the most performed surgery, and 10% of patients relapsed, mainly in the lymph nodes (87.5%). The mean follow-up of the patients was 18 months, with an estimated overall survival at five years of 59.1%. However, 25% of patients were followed up for up to 3 months, losing follow-up. Conclusion: the State of Rio Grande do Norte has a high incidence of penile cancer with a high frequency of locally advanced tumors at diagnosis and in younger patients younger than 50. Furthermore, socioeconomic factors interfere with early diagnosis and hinder access to specialized services. Objective NorteBrazil Brazil literature Methods crosssectional cross sectional 9 20112018, 20112018 2011 2018, 2018 2011-2018 Cancer Results carcinoma 5 interior brown illiterate education 68 T2 T =T2 30 involvement 21 2 1 2.1 disease 202 20 20.2 IV surgery 10 relapsed 87.5%. 875 87.5% . 87 (87.5%) followup follow months 591 59 59.1% However 25 followup. up. Conclusion Furthermore services 2011201 201 2011-201 6 =T 2. 20. 87.5 8 (87.5% 59.1 201120 2011-20 87. (87.5 59. 20112 2011-2 (87. 2011- (87 (8 (

https://doi.org/10.1590/0100-6991e-20233586-en

13.

Patient safety with covid-19 in hospital units: a scoping review covid19 covid 19 covid-1 units covid1 1 covid-
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Leite, Fernanda de Macedo Coelho

; Oliveira, Eloysa dos Santos

; Silva, Bruna Vilar Soares da

; Melo, Evelin Beatriz Bezerra de

; Dantas, Rodrigo Assis Neves

; Dantas, Daniele Vieira

Revista Brasileira de Enfermagem

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2023, Volume 76 Suppl. 1 elocation e20220557

Abstract: Es En Pt | Text: Es En Pt | PDF: Es | PDF: En | PDF: Pt

RESUMEN Objetivo: Mapear, en la literatura científica, las acciones adoptadas para promover la seguridad del paciente con covid-19 en el contexto hospitalario. Métodos: Se trata de una revisión de ámbito de acuerdo con el Instituto Joanna Briggs, utilizando el Checklist Preferred Reporting Items for Systematic Reviews and Meta-Analyses Extension for Scoping Reviews. En abril de 2022, fueron realizadas búsquedas en nueve fuentes de datos. Los resultados fueron sintetizados en un cuadro y analizados de manera descriptiva. Resultados: Fueron seleccionados 15 estudios para componer la muestra final. La mayoría de los artículos se refieren a estudios de cohorte, seguidos de ensayos clínicos. Cuanto las áreas de actuación, notado predominancia de los centros quirúrgicos, seguidos por Unidades de Cuidados Intensivos adulto y pediátrica. Conclusiones: Con esta revisión, fue posible mapear medidas como planes de contingencia y reorganización de lechos, cuartos y salas quirúrgicas, además del aislamiento y distanciamiento practicados por pacientes y profesionales. Objetivo Mapear científica covid19 covid 19 covid-1 hospitalario Métodos Briggs MetaAnalyses Meta Analyses 2022 datos descriptiva Resultados 1 final cohorte clínicos actuación quirúrgicos pediátrica Conclusiones lechos quirúrgicas profesionales covid1 covid- 202 20 2

ABSTRACT Objective: Map, in the scientific literature, the actions taken to promote the safety of patients with covid-19 in the hospital context. Methods: This is a scoping review according to the Joanna Briggs Institute, using the Checklist Preferred Reporting Items for Systematic Reviews and Meta-Analyses Extension for Scoping Reviews. In April 2022, searches were performed on nine data sources. The results were summarized in a table and analyzed descriptively. Results: Fifteen studies were selected to compose the final sample. Most articles refer to cohort studies, followed by clinical trials. As for the areas of activity, there was a predominance of surgical centers, followed by adult and pediatric Intensive Care Units. Conclusions: With this review, it was possible to map measures such as contingency plans and reorganization of beds, rooms, and operating rooms, in addition to the isolation and distancing practiced by patients and professionals. Objective Map literature covid19 covid 19 covid-1 context Methods Institute MetaAnalyses Meta Analyses 2022 sources descriptively Results sample trials activity centers Units Conclusions beds rooms professionals covid1 1 covid- 202 20 2

RESUMO Objetivo: Mapear, na literatura científica, as ações adotadas para promover a segurança do paciente com covid-19 no contexto hospitalar. Métodos: Trata-se de uma revisão de escopo de acordo com o Instituto Joanna Briggs, utilizando o Checklist Preferred Reporting Items for Systematic Reviews and Meta-Analyses Extension for Scoping Reviews. Em abril de 2022, foram realizadas buscas em nove fontes de dados. Os resultados foram sintetizados em um quadro e analisados de forma descritiva. Resultados: Foram selecionados 15 estudos para compor a amostra final. A maioria dos artigos se refere a estudos de coorte, seguidos de ensaios clínicos. Quanto às áreas de atuação, notou-se predominância dos centros cirúrgicos, seguidos por Unidades de Terapia Intensiva adulto e pediátrica. Conclusões: Com esta revisão, foi possível mapear medidas como planos de contingência e reorganização de leitos, quartos e salas de cirurgias, além do isolamento e distanciamento praticados pelos pacientes e profissionais. Objetivo Mapear científica covid19 covid 19 covid-1 hospitalar Métodos Tratase Trata Briggs MetaAnalyses Meta Analyses 2022 dados descritiva Resultados 1 final coorte clínicos atuação notouse notou cirúrgicos pediátrica Conclusões leitos cirurgias profissionais covid1 covid- 202 20 2

https://doi.org/10.1590/0034-7167-2022-0557

14.

IMPACTO-MR: um estudo brasileiro de plataforma nacional para avaliar infecções e multirresistência em unidades de terapia intensiva IMPACTOMR IMPACTO MR IMPACTO-MR
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Tomazini, Bruno M

; Nassar Jr, Antonio Paulo

; Lisboa, Thiago Costa

; Azevedo, Luciano César Pontes de

; Veiga, Viviane Cordeiro

; Catarino, Daniela Ghidetti Mangas

; Fogazzi, Debora Vacaro

; Arns, Beatriz

; Piastrelli, Filipe Teixeira

; Dietrich, Camila

; Negrelli, Karina Leal

; Jesuíno, Isabella de Andrade

; Reis, Luiz Fernando Lima

; Mattos, Renata Rodrigues de

; Pinheiro, Carla Cristina Gomes

; Luz, Mariane Nascimento

; Spadoni, Clayse Carla da Silva

; Moro, Elisângela Emilene

; Bueno, Flávia Regina

; Sampaio, Camila Santana Justo Cintra

; Silva, Débora Patrício

; Baldassare, Franca Pellison

; Silva, Ana Cecilia Alcantara

; Veiga, Thabata

; Barbante, Leticia

; Lambauer, Marianne

; Campos, Viviane Bezerra

; Santos, Elton

; Santos, Renato Hideo Nakawaga

; Laranjeiras, Ligia Nasi

; Valeis, Nanci

; Santucci, Eliana

; Miranda, Tamiris Abait

; Patrocínio, Ana Cristina Lagoeiro do

; Carvalho, Andréa de

; Sousa, Eduvirgens Maria Couto de

; Sousa, Ancelmo Honorato Ferraz de

; Malheiro, Daniel Tavares

; Bezerra, Isabella Lott

; Rodrigues, Mirian Batista

; Malicia, Julliana Chicuta

; Silva, Sabrina Souza da

; Gimenes, Bruna dos Passos

; Sesin, Guilhermo Prates

; Zavascki, Alexandre Prehn

; Sganzerla, Daniel

; Medeiros, Gregory Saraiva

; Santos, Rosa da Rosa Minho dos

; Silva, Fernanda Kelly Romeiro

; Cheno, Maysa Yukari

; Abrahão, Carolinne Ferreira

; Oliveira Junior, Haliton Alves de

; Rocha, Leonardo Lima

; Nunes Neto, Pedro Aniceto

; Pereira, Valéria Chagas

; Paciência, Luis Eduardo Miranda

; Bueno, Elaine Silva

; Caser, Eliana Bernadete

; Ribeiro, Larissa Zuqui

; Fernandes, Caio Cesar Ferreira

; Garcia, Juliana Mazzei

; Silva, Vanildes de Fátima Fernandes

; Santos, Alisson Junior dos

; Machado, Flávia Ribeiro

; Souza, Maria Aparecida de

; Ferronato, Bianca Ramos

; Urbano, Hugo Corrêa de Andrade

; Moreira, Danielle Conceição Aparecida

; Souza-Dantas, Vicente Cés de

; Duarte, Diego Meireles

; Coelho, Juliana

; Figueiredo, Rodrigo Cruvinel

; Foreque, Fernanda

; Romano, Thiago Gomes

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Revista Brasileira de Terapia Intensiva

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dec 2022, Volume 34 N. 4 Pages 418 - 425

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Objetivo: Descrever o IMPACTO-MR, um estudo brasileiro de plataforma nacional em unidades de terapia intensiva focado no impacto das infecções por bactérias multirresistentes relacionadas à assistência à saúde. Métodos: Descrevemos a plataforma IMPACTO-MR, seu desenvolvimento, critérios para seleção das unidades de terapia intensiva, caracterização da coleta de dados, objetivos e projetos de pesquisa futuros a serem realizados na plataforma. Resultados: Os dados principais foram coletados por meio do Epimed Monitor System® e consistiram em dados demográficos, dados de comorbidades, estado funcional, escores clínicos, diagnóstico de internação e diagnósticos secundários, dados laboratoriais, clínicos e microbiológicos e suporte de órgãos durante a internação na unidade de terapia intensiva, entre outros. De outubro de 2019 a dezembro de 2020, 33.983 pacientes de 51 unidades de terapia intensiva foram incluídos no banco de dados principal. Conclusão: A plataforma IMPACTO-MR é um banco de dados clínico brasileiro de unidades de terapia intensiva focado na pesquisa do impacto das infecções por bactérias multirresistentes relacionadas à assistência à saúde. Essa plataforma fornece dados para o desenvolvimento e pesquisa de unidades de terapia intensiva individuais e ensaios clínicos observacionais e prospectivos multicêntricos. Objetivo IMPACTOMR, IMPACTOMR IMPACTO MR, MR saúde Métodos Resultados System demográficos comorbidades funcional secundários laboratoriais outros 201 2020 33983 33 983 33.98 5 principal Conclusão multicêntricos 20 202 3398 3 98 33.9 2 339 9 33.

ABSTRACT Objective: To describe the IMPACTO-MR, a Brazilian nationwide intensive care unit platform study focused on the impact of health care-associated infections due to multidrug-resistant bacteria. Methods: We described the IMPACTO-MR platform, its development, criteria for intensive care unit selection, characterization of core data collection, objectives, and future research projects to be held within the platform. Results: The core data were collected using the Epimed Monitor System® and consisted of demographic data, comorbidity data, functional status, clinical scores, admission diagnosis and secondary diagnoses, laboratory, clinical, and microbiological data, and organ support during intensive care unit stay, among others. From October 2019 to December 2020, 33,983 patients from 51 intensive care units were included in the core database. Conclusion: The IMPACTO-MR platform is a nationwide Brazilian intensive care unit clinical database focused on researching the impact of health care-associated infections due to multidrug-resistant bacteria. This platform provides data for individual intensive care unit development and research and multicenter observational and prospective trials. Objective IMPACTOMR, IMPACTOMR IMPACTO MR, MR careassociated associated multidrugresistant multidrug resistant bacteria Methods selection collection objectives Results System status scores diagnoses laboratory stay others 201 2020 33983 33 983 33,98 5 Conclusion trials 20 202 3398 3 98 33,9 2 339 9 33,

https://doi.org/10.5935/0103-507x.20220209-pt

15.

[SciELO Preprints] - Factors related to survival in Intensive Care Unit patients with Covid-19: a study from a single center in Brazil
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Sardenberg, Rodrigo A. S. Roberto, Gabriel Antonio Silva, Catarina Marchon da Galvão, Andrea Santos Pinho, Daniela Jesus Meireles Ribeiro Sachelli, Tabatta Zambotto Diniz, Gabriela Bezerra Freitas

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Publication date: 2022-07-21

Abstract: En

Introduction: Analysis of the outcome of 268 ICU patients in a single-center, as well the impact of viral infection on patients with preexisting medical conditions and how these factors affected survival and hospital stay. Methodology: Patients admitted to the ICU from March-August, 2020 were retrospectively analyzed under the same protocol at Hospital Alemão Oswaldo Cruz, São Paulo, Brazil. Several factors were considered and the results were presented using 95% confidence intervals. For statistical significance, p <0.05 was adopted. Results: Patient median age was 72 years, 64,2 years for discharged patients and 79.9 years for those deceased (p<0.001). The most common comorbidities were: systemic arterial hypertension, diabetes, thyroid disease, cardiovascular and kidney disease. Predictors of survival through univariate analysis: myalgia (p=0.001), cerebrovascular disease (p=0.002), COPD (p=0.003), dementia (p=0.000), mechanical ventilation (p=0.000), dialysis (0.000), vasopressor use (0.000), SAPS3 (0.000), lymphopenia (p=0.004), elevated D-dimer (P=0.011), time in ICU before tracheostomy (p=0.002), and performing a tracheostomy (p=0.000). The independent predictors of mortality were: advanced age (p=0.003) and tracheostomy performed in ICU (p=0.002). Discussion: COVID-19 affects usually older adults, where there already is a higher fatality rate. Acute respiratory distress syndrome is the primary cause of death and <5% of patients were reported as experiencing co-infection at admission. Conclusion: age, vasopressor use in patients with tracheostomy, and systemic coronary disease, heart failure, neoplasia, and COPD, were found to be significantly associated with COVID-19 severity.

https://doi.org/10.1590/SciELOPreprints.4453

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