Abstract Introduction: Multicenter research initiatives in Brazilian dialysis centers are scarce. We described the recruitment and implementation phases of the SARC-HD study, aimed at investigating sarcopenia and its impact on adverse clinical outcomes. Methods: The SARC-HD is a cohort study being conducted with patients on hemodialysis in Brazil. The recruitment phase was defined as the period from the invitation to the center until the start of patient enrollment, whereas the implementation phase lasted from then until the completion of enrollment and baseline data collection. Upon implementation, a structured questionnaire was distributed to collect feedback from principal investigators. Results: 21 centers from three Brazilian regions consented to participate, with two dropping out. Ten principal investigators oversaw the 19 sites. Nine centers (47%) were funded entirely by health insurance companies. A total of 1525 patients were screened for eligibility and 1008 were enrolled, with a 66.1% recruitment rate. Recruitment and baseline data collection took 12 [interquartile range: 5–15] weeks. Qualitative content analysis identified barriers such as a lack of infrastructure and logistics for research. Facilitators included the management and organization of the steering committee. Data collection challenges were mainly reported with the subjective 7-point global assessment and the international physical activity questionnaire. The main challenge for the ongoing maintenance phase will be the lack of standardized information in electronic health records. Conclusions: The recruitment and implementation phases of the multicenter SARC-HD study were feasible. Barriers and facilitators identified by principal investigators may help future multicenter initiatives to integrate research-related tasks into clinical routine, facilitating successful experiences. Introduction scarce SARCHD SARC HD outcomes Methods Brazil Results 2 participate out 1 sites 47% 47 (47% companies 152 100 enrolled 661 66 66.1 rate interquartile range 5–15 515 5 15 weeks committee 7point point 7 records Conclusions feasible researchrelated related routine experiences 4 (47 10 6 66. 5–1 51 (4 5– (

Resumo Introdução: Pesquisa multicêntrica em centros de diálise brasileiros são escassas. Descrevemos as fases de recrutamento e implementação do estudo SARC-HD, visando investigar a sarcopenia e seu impacto em desfechos clínicos adversos. Métodos: O SARC-HD é um estudo de coorte realizado com pacientes em hemodiálise no Brasil. A fase de recrutamento foi considerada o período entre convite ao centro e início da inclusão de pacientes, enquanto a fase de implementação durou a partir de então até a conclusão do recrutamento e coleta de dados basais. Após a implementação, um questionário estruturado foi distribuído para coletar feedback dos principais pesquisadores. Resultados: 21 centros de três regiões brasileiras consentiram em participar, com duas desistências. Dez pesquisadores principais supervisionaram 19 locais. Nove centros (47%) eram totalmente financiados por planos de saúde. 1525 pacientes foram avaliados para elegibilidade e 1008 foram incluídos, com taxa de recrutamento de 66,1%. Recrutamento e coleta de dados basais levaram 12 semanas [intervalo interquartil: 5–15]. A análise qualitativa de conteúdo identificou barreiras como falta de infraestrutura e logística para pesquisa. Os facilitadores incluíram gestão e organização do comitê gestor. Os desafios da coleta de dados foram relatados principalmente quanto à avaliação global subjetiva de 7 pontos e o questionário internacional de atividade física. O principal desafio para a fase de manutenção será a falta de informações padronizadas nos prontuários eletrônicos. Conclusões: As fases de recrutamento e implementação do estudo multicêntrico SARC-HD foram viáveis. Barreiras e facilitadores identificados pelos pesquisadores principais podem auxiliar futuras iniciativas multicêntricas a integrar tarefas relacionadas à pesquisa na rotina clínica, facilitando experiências bem-sucedidas. Introdução escassas SARCHD, SARCHD SARC HD, HD adversos Métodos Brasil Resultados 2 participar desistências 1 locais 47% 47 (47% saúde 152 100 incluídos 661 66 66,1% intervalo interquartil 5–15. 515 5–15 . 5 15 5–15] gestor física eletrônicos Conclusões viáveis clínica bemsucedidas. bemsucedidas bem sucedidas. sucedidas bem-sucedidas 4 (47 10 6 66,1 51 5–1 (4 66, 5– (

EFFECT OF LIQUID SWINE WASTEWATER DOSES ON PHYSICAL, CHEMICAL AND ELECTROCHEMICAL ATTRIBUTES IN A CERRADO OXISOL. The addition of organic residues enhances soil and plant organic matter and nutrient content. To gauge the impact of varying liquid swine waste (LSW) levels on soil, we studied changes in a clayey Oxisol’s physical, chemical, and electrochemical traits from the Cerrado. LSW doses (0, 50, 150, 450, 600 m3 ha−1) were applied to the 0-0.20 m layer in a randomized design with three replicates. Post a 30-day incubation at 60% field capacity, the soil underwent mineralogical, physical (clay dispersed in water - CDW), chemical (sodium adsorption ratio - SAR, cation exchange capacity - CEC, base saturation - V%), and electrochemical (pH in H2O and KCl, ApH, point of zero charge - PZC, point of zero salt effect - PZSE, surface electric potential - iµo, and electrical conductivity - EC) analyses. The levels of exchangeable Ca, K, Mg, Na, and available P increased with increasing LSW doses. Increasing LSW doses in the soil led to an increase in EC, but soil salinization was not observed at the highest dose. With the application of LSW doses, there was a decrease in pH, ApH, PZSE, and an increase in CEC, PZC and ψo. Despite the increase in ψo, low clay dispersibility was observed. PHYSICAL OXISOL content (LSW Oxisols Oxisol s Cerrado 0, 0 (0 50 150 450 60 ha−1 ha1 ha 1 00.20 0020 0.20 20 0-0.2 replicates 30day day 30 mineralogical CDW, CDW , CDW) sodium SAR CEC V%, V V% V%) pH HO H O KCl ApH PZSE iµo EC analyses Ca K Mg Na dose ψo ( 5 15 45 6 ha− 00 00.2 002 020 0.2 2 0-0. 3 4 00. 02 0. 0-0 0-

Faced with the global challenge of water treatment, the investigation of the removal of endocrine disruptor compounds (EDCs) in aquatic environments is essential to protect human and animals health. In this study, a novel nanocomposite was prepared from biochar from agricultural waste (corn cob) and maghemite (γ-Fe2O3) nanoparticles, named PCCN, to remove four EDCs (triclosan, 17α-ethinylestradiol, methylparaben, and bisphenol A) from aqueous solutions by adsorption. For the characterization of PCCN, the advanced techniques Fourier transform infrared spectroscopy (FTIR), Brunauer-Emmett-Teller analysis (BET), pH of point of zero charge (pHpzc), scanning electron microscopy (SEM), transmission electron microscopy (TEM), X-ray diffraction (XRD) and thermogravimetry (TGA) were employed. Competitive adsorption equilibrium studies of EDCs were performed with PCCN and compared to unmodified biochar (PCC). The pH effect showed that optimal adsorption of EDCs was at pH 8.0 for PCC and pH 6.0 for PCCN. The salt concentration did not influence EDCs in the adsorption. In the adsorption isotherm, the results fitted the Freundlich isotherm model (R2 > 0.903) and the adsorption kinetics were well described by the pseudo-second-order model (R2 > 0.985). Furthermore, the desorption studies indicated that the PCCN can be reused. Thus, the investigation suggests PCCN has promising potential in the removal of EDCs from wastewater. treatment (EDCs health study corn cob γFe2O3 γFeO γ Fe2O3 Fe O (γ-Fe2O3 nanoparticles triclosan, triclosan (triclosan 17αethinylestradiol, 17αethinylestradiol αethinylestradiol 17α ethinylestradiol, ethinylestradiol α 17α-ethinylestradiol methylparaben A FTIR, FTIR , (FTIR) BrunauerEmmettTeller Brunauer Emmett Teller BET, BET (BET) pHpzc, pHpzc (pHpzc) SEM, SEM (SEM) TEM, TEM (TEM) Xray X ray XRD (XRD TGA (TGA employed PCC. . (PCC) 80 8 0 8. 60 6 6. R2 R (R 0.903 0903 903 pseudosecondorder pseudo second order 0.985. 0985 0.985 985 0.985) Furthermore reused Thus wastewater γFe γFe2O FeO Fe2O (γ-Fe2O (FTIR (BET (pHpzc (SEM (TEM (PCC 0.90 090 90 098 0.98 98 0.9 09 9 0.

RESUMO: Com o avanço da cafeicultura, múltiplas características devem ser consideradas na seleção de plantas, que devem apresentar um conjunto de atributos favoráveis. O rendimento, definido como a relação de massas entre os frutos maduros e os grãos processados, é um importante componente da produtividade. Este estudo tem como objetivo caracterizar o rendimento ao longo de duas colheitas de 57 clones comercializados em domínio público e 10 cultivares registradas. A análise considera efeitos de genótipos, medições e estimativas de ganhos com a seleção. De acordo com o ciclo de maturação de cada clone, amostras de café cereja foram colhidas considerando um delineamento fatorial inteiramente ao acaso para a caracterização dos efeitos de genótipos, anos e interação genótipo × anos (GA). A secagem, o descascamento e o rendimento foram avaliados individualmente. Apesar dos efeitos significativos da interação GA, os genótipos apresentaram pequenas mudanças no ordenamento de uma medição para a outra. Clones com maior rendimento, entre eles, LB30, BRS1216, LB12, N7, LB10, LB20, BRS3220 e AS5 apresentaram rendimento médio de 25,51% associado a estimativas de ganho de 12,17%. Por outro lado, clones de menor rendimento, como BG180, GJ30, GJ20, AS7, AS10, P42, N1 e P60 tiveram uma média de 19,15% associada a uma redução de 14,02%. A partir da distribuição dos valores, 19,4, 62,7 e 17,9% dos genótipos apresentaram rendimento classificados como alto, médio e baixo, subsidiando o melhor cultivo dos genótipos avaliados. RESUMO cafeicultura plantas favoráveis processados produtividade 5 1 registradas clone GA. GA . (GA) secagem individualmente outra eles LB30 LB BRS1216 BRS LB12 N7 N LB10 LB20 BRS322 AS 2551 25 51 25,51 1217 12 17 12,17% lado BG180 BG GJ30 GJ GJ20 AS7 AS10 P42 P P6 1915 19 15 19,15 1402 14 02 14,02% valores 194 4 19,4 627 62 7 62, 179 9 17,9 alto baixo (GA LB3 BRS121 LB1 LB2 BRS32 255 2 25,5 121 12,17 BG18 GJ3 GJ2 AS1 P4 191 19,1 140 0 14,02 19, 6 17, BRS12 BRS3 25, 12,1 BG1 14,0 BRS1 12, 14,

ABSTRACT: With advancements in coffee cultivation, several traits may be considered in selection of plants, which must exhibit a set of favorable characteristics. The outturn index, defined as the relationship between the mass of mature fruit and processed beans, emerges as a key factor influencing productivity. This study characterized the outturn over two harvests of 57 clones marketed in the public domain and 10 registered cultivars. The analysis considers the effects of genotypes, measurements, and genetic progress achieved through plant selection. According to the maturation cycle of each clone, washed samples of cherry coffee were collected considering a completely randomized factorial design for characterization of the effects of genotypes, years, and the genotype × years (GY) interaction. The drying, peeling, and the outturn index were individually assessed. Despite the significant effects of the GY interaction, genotypes demonstrated minimal alterations in their ranking across measurements. Clones with higher outturn, including LB30, BRS1216, LB12, N7, LB10, LB20, BRS3220, and AS5, exhibited an average outturn of 25.51%, reflecting a gain of 12.17%. Conversely, clones with lower outturn, such as BG180, GJ30, GJ20, AS7, AS10, P42, N1, and P60, had an average of 19.15%, indicating a reduction of 14.02% compared to the general mean. Analyzing the distribution of the outturn values, 19.4%, 62.7%, and 17.9% of genotypes were classified as high, medium, and low outturn, respectively, providing valuable insights for optimal cultivation strategies. ABSTRACT plants characteristics beans productivity 5 1 cultivars measurements clone (GY interaction drying peeling assessed LB30 LB BRS1216 BRS LB12 N7 N LB10 LB20 BRS3220 AS5 AS 2551 25 51 25.51% 1217 12 17 12.17% Conversely BG180 BG GJ30 GJ GJ20 AS7 AS10 P42 P N1 P60 1915 19 15 19.15% 1402 14 02 14.02 mean values 194 4 19.4% 627 62 7 62.7% 179 9 17.9 high medium respectively strategies LB3 BRS121 LB1 LB2 BRS322 255 2 25.51 121 12.17 BG18 GJ3 GJ2 AS1 P4 P6 191 19.15 140 0 14.0 19.4 6 62.7 17. BRS12 BRS32 25.5 12.1 BG1 19.1 14. 19. 62. BRS1 BRS3 25. 12.

Alfred Schaeffer (1879-1957) was a German chemist who arrived in Minas Gerais in 1911 hired by the state government to organize the state health service in its newly established capital. He directed the Laboratory of Chemical Analysis of the State, and his analytical methods in dairy and mineral waters became a reference in Brazil. He also became professor of Chemistry at the new Faculty of Medicine of Belo Horizonte and founded the Chemistry Institute of the Engineering School in that city, influencing several students who became important names in Brazilian science. In addition, he was responsible for the assembly and technical coordination of pioneering industries in the dairy and wood distillation sector in the city of Santos Dumont. Later he assumed the post of technical director of Merck, also in Minas Gerais. Moving to Rio de Janeiro, he assumed a chair at the Technical School, working in teaching and research, and remained active even after retiring, publishing in important scientific journals. 18791957 1879 1957 (1879-1957 191 capital State Brazil science addition Dumont Merck Janeiro research retiring journals 1879195 187 195 (1879-195 19 187919 18 (1879-19 1 18791 (1879-1 (1879- (1879 (187 (18 (1 (

RESUMO Objetivo: Examinar a associação entre o tempo de tela autorreportado e os sintomas de estresse, ansiedade e depressão em adolescentes. Métodos: Foi realizado estudo com delineamento transversal com 982 adolescentes entre 12-15 anos, matriculados na rede pública de ensino da cidade de Jacarezinho (PR). Para mensurar o tempo de tela, os adolescentes responderam à pergunta: “Considerando um dia típico, quanto tempo você passa assistindo TV, jogando videogame, usando computador ou smartphone?”. O questionário DASS-21 (versão curta) foi utilizado para avaliar os sintomas de depressão, ansiedade e estresse. Análises brutas e ajustadas (idade, sexo e nível de escolaridade materna) entre tempo de tela e indicadores de saúde mental foram realizadas por meio do modelo de regressão linear generalizado, com distribuição de Poisson, adotando a significância de p<0,05. Resultados: Maiores sintomas depressivos foram observados em adolescentes com tempo de tela de 4–6 horas/dia (RP 1,35, IC95% 1,13–1,61) e ≥6 horas/dia (RP 1,88, IC95% 1,62–2,19) quando comparados com seus pares com ≤2 horas/dia. O mesmo foi observado para os sintomas de ansiedade com tempo de tela de 4–6 horas/dia (RP 1,23, IC95% 1,04–1,46) e ≥6 horas/dia (RP 1,50, IC95% 1,28–1,77); e estresse, com 4–6 horas/dia (RP 1,25, IC95% 1,08–1,44) e ≥6 horas/dia (RP 1,49, IC95% 1,30–1,71), também comparados com seus pares com ≤2 horas/dia. Conclusões: O tempo de tela foi associado positivamente com os sintomas de depressão, ansiedade e estresse em adolescentes. Atenção especial deve ser dada àqueles que passam mais de quatro horas por dia em frente a uma tela. Objetivo Métodos 98 1215 12 15 12-1 anos PR. PR . (PR) pergunta Considerando típico TV videogame smartphone. smartphone smartphone?” DASS21 DASS 21 DASS-2 versão curta idade, idade (idade materna generalizado Poisson p005 p 0 05 p<0,05 Resultados 46 4 6 4– horasdia RP 135 1 35 1,35 IC95 IC 1,13–1,61 113161 13 61 ≥ 188 88 1,88 1,62–2,19 162219 62 2 19 ≤ 123 23 1,23 1,04–1,46 104146 04 150 50 1,50 1,28–1,77 128177 28 77 1,28–1,77) 125 25 1,25 1,08–1,44 108144 08 44 149 49 1,49 1,30–1,71, 130171 1,30–1,71 , 30 71 1,30–1,71) Conclusões 9 121 12- (PR smartphone? DASS2 DASS- p00 p<0,0 3 1,3 IC9 1,13–1,6 11316 18 8 1,8 1,62–2,1 16221 1,2 1,04–1,4 10414 5 1,5 1,28–1,7 12817 7 1,08–1,4 10814 14 1,4 13017 1,30–1,7 p0 p<0, 1, 1,13–1, 1131 1,62–2, 1622 1,04–1, 1041 1,28–1, 1281 1,08–1, 1081 1301 1,30–1, p<0 1,13–1 113 1,62–2 162 1,04–1 104 1,28–1 128 1,08–1 108 130 1,30–1 p< 1,13– 11 1,62– 16 1,04– 10 1,28– 1,08– 1,30– 1,13 1,62 1,04 1,28 1,08 1,30 1,1 1,6 1,0

ABSTRACT Objective: To examine the associations between self-reported screen time and symptoms of stress, anxiety, and depression in adolescents. Methods: A cross-sectional study was conducted with 982 adolescents aged between 12 and 15 years, enrolled in public schools in Jacarezinho (PR), Brazil. Screen time was assessed by the question “Considering a typical day, how much time do you spend watching TV, playing videogame, using computer or smartphone?” The DASS-21 questionnaire (short form) was used to assess symptoms of depression, anxiety, and stress. Crude and adjusted analyses (age, sex, and maternal level of education) between screen time and mental disorders symptoms were performed using general linear regression models, with Poisson distribution, with significance level at p<0.05. Results: Higher depressive symptoms were observed in adolescents who reported screen time of 4–6 hours/day (PR 1.35, 95%CI 1.13–1.61) and ≥6 hours/day (PR 1.88, 95%CI 1.62–2.19), compared with their pairs with <2 hours/day. The same was observed for anxiety symptoms with screen time of 4–6 hours/day (PR 1.23, 95%CI 1.04–1.46) and ≥6 hours/day (PR 1.50, 95%CI 1.28–1.77); and stress, with 4–6 hours/day (PR 1.25, 95%CI 1.08–1.44) and ≥6 hours/day (PR 1.49, 95%CI 1.30–1.71), also compared with their pairs with <2 hours/day. Conclusions: Screen time was positively associated with depressive, anxiety, and stress symptoms in adolescents. Special attention should be given to those who spend more than four hours a day in front of a screen. Objective selfreported self Methods crosssectional cross sectional 98 1 years PR, PR , (PR) Brazil Considering TV videogame smartphone smartphone? DASS21 DASS 21 DASS-2 short form age, age (age sex education models distribution p005 p 0 05 p<0.05 Results 46 4 6 4– hoursday 135 35 1.35 95CI CI 95 1.13–1.61 113161 13 61 ≥ 188 88 1.88 1.62–2.19, 162219 1.62–2.19 62 2 19 1.62–2.19) < 123 23 1.23 1.04–1.46 104146 04 150 50 1.50 1.28–1.77 128177 28 77 1.28–1.77) 125 25 1.25 1.08–1.44 108144 08 44 149 49 1.49 1.30–1.71, 130171 1.30–1.71 30 71 1.30–1.71) Conclusions 9 DASS2 DASS- p00 p<0.0 3 1.3 1.13–1.6 11316 18 8 1.8 16221 1.62–2.1 1.2 1.04–1.4 10414 5 1.5 1.28–1.7 12817 7 1.08–1.4 10814 14 1.4 13017 1.30–1.7 p0 p<0. 1. 1.13–1. 1131 1622 1.62–2. 1.04–1. 1041 1.28–1. 1281 1.08–1. 1081 1301 1.30–1. p<0 1.13–1 113 162 1.62–2 1.04–1 104 1.28–1 128 1.08–1 108 130 1.30–1 p< 1.13– 11 16 1.62– 1.04– 10 1.28– 1.08– 1.30– 1.13 1.62 1.04 1.28 1.08 1.30 1.1 1.6 1.0

ABSTRACT Arbuscular mycorrhizal fungi increase water and nutrient absorption from the soil by plants. However, its benefits to plants vary depending on the inoculated species. This study aimed to determine the influence of different species of mycorrhizal fungi on the development and productivity of grain sorghum cultivars. The experiment was conducted in a greenhouse in a completely randomized design in a 2 x 5 factorial scheme, consisting of two sorghum cultivars (BRS 310 and BRS 330) and five treatments (control without inoculation and four species of arbuscular mycorrhizal fungi: Gigaspora margarita, Glomus formosanum, Acaulospora scrobiculata, and Scutellospora pellucida), with four replications. Plant height, stem diameter, leaf area, length, volume, specific surface area, root diameter, shoot dry mass, root dry mass, thousand-grain weight, grain productivity, colonization, dependence, and mycorrhizal efficiency were evaluated. The results showed that inoculation with the species S. pellucida induced higher root and shoot development of plants of the cultivar BRS 310, as well as higher productivity of sorghum grains. The cultivar BRS 330 showed higher root development when inoculated with the species G. formosanum and a higher shoot development when inoculated with the species A. scrobiculata. Mycorrhizal dependence for grain productivity was low and varied with the inoculated species of mycorrhizal fungi. The mycorrhizal efficiency for shoot dry mass was higher with the inoculation of A. scrobiculata and S. pellucida in the cultivar BRS 310 and A. scrobiculata and G. margarita in the cultivar BRS 330. However scheme 31 control pellucida, , pellucida) replications height diameter area length volume thousandgrain thousand weight colonization evaluated S grains 33 G A 3

RESUMO: A osteologia desempenha um papel indispensável para o conhecimento dos padrões de normalidade das diversas espécies, sendo a base para o entendimento zoológico. Mazama nana é bastante conhecido no Brasil, porém descrições morfológicas básicas acerca da espécie são escassas, enquanto Subulo gouazoubira, revalidação atual de Mazama gouazoubira, também é incidente no Brasil e, atualmente, tem sido alvo de diversos estudos filogenéticos. Nesse escopo, no presente estudo, foram preparadas, osteologicamente, 19 cabeças de cervídeos (16 Subulo gouazoubira e três Mazama nana) e, em seguida, tomografias computadorizadas (TCs) foram realizadas a fim de aprimorar as formas de avaliação de acidentes ósseos, além de estruturas internas e forames mediante técnicas de reconstrução em três dimensões (3D) devido a difícil visibilidade em peças intactas. Posteriormente, realizou-se um comparativo entre as reconstruções, fotografias digitais e secções tomográficas transversais do crânio, o qual possibilitou a visualização de peculiaridades e exclusividades anatômicas, como a presença da fenestra nasolacrimomaxilar, detalhamento dos seios paranasais e arquitetura de ossos finos, além do formato exclusivo dos ossos cranianos, em comparação a outras espécies, que apresentam um fenótipo único e genuíno. RESUMO espécies zoológico escassas atualmente filogenéticos escopo estudo preparadas osteologicamente 1 16 (1 seguida TCs (TCs ósseos 3D D (3D intactas Posteriormente realizouse realizou se reconstruções crânio anatômicas nasolacrimomaxilar finos cranianos genuíno (

ABSTRACT: Osteology plays an indispensable role in understanding the normal patterns of different species, serving as the foundation for zoological understanding. Mazama nana is well-known in Brazil; however, basic morphological descriptions of the species are scarce, while Subulo gouazoubira, currently revalidated as Mazama gouazoubira, is also prevalent in Brazil and has recently been the subject of various phylogenetic studies. In this respect, in the present study, 19 cervid heads (16 Subulo gouazoubira and three Mazama nana) were osteologically prepared. Next, computed tomographies (CTs) were performed to enhance the assessment of bone accidents, as well as internal structures and foramina through three-dimensional (3D) reconstruction techniques due to the difficult visibility in intact specimens. A comparison was then made between the reconstructions, digital photographs, and CT cross-sections of the skull, which enabled the visualization of anatomical peculiarities and exclusivities, such as nasolacrimal-maxillary fenestra, paranasal sinuses, and thin bone architecture, as well as the unique shape of cranial bones, compared to other species that exhibit a unique and genuine phenotype. ABSTRACT wellknown known however scarce studies respect study 1 16 (1 prepared Next CTs (CTs accidents threedimensional dimensional 3D D (3D specimens reconstructions photographs crosssections cross sections skull exclusivities nasolacrimalmaxillary nasolacrimal maxillary fenestra sinuses architecture bones phenotype (

RESUMO: A mastite bovina é a doença mais impactante na indústria de laticínios e é caracterizada por uma complexidade de agentes causais, os quais têm revelado uma variação geográfica entre regiões e países. Os patógenos relacionados à mastite têm sido tradicionalmente classificados como contagiosos ou ambientais, com base na fonte de infecção ou origem e nas vias de transmissão. Além disso, a gravidade das infecções mamárias tem sido associada à virulência dos patógenos, e ao estado imunológico e nutricional dos animais. Considerando esse cenário, investigamos os agentes etiológicos, os escores de gravidade clínica e os dados de dias em lactação (DEL) em 4.273 casos clínicos de mastite bovina em dez fazendas de grande porte, quatro localizadas no sudoeste do estado de São Paulo e seis no sul do Estado de Minas Gerais, Brasil. Streptococcus dysgalactiae (283/4.273 = 6,6%), Escherichia coli (190/4.273 = 4,4%), Prototheca spp. (112/4.273 = 2,6%) e Streptococcus uberis (95/4.273 = 2,2%) foram os patógenos predominantes isolados. Entre os 4.273 casos clínicos, a pontuação de gravidade clínica estava disponível em 43,8% (1.871/4.273) dos animais. Desses, 69,8% (1.306/1.871), 27,3% (510/1.871) e 2,9% (55/1.871) foram classificados como leves, moderados e graves, respectivamente. Os patógenos foram observados principalmente em amostras obtidas durante os primeiros 100 dias em lactação, e a gravidade clínica foi principalmente classificada como leve. Nossos resultados contribuem para a identificação etiológica, a pontuação de gravidade clínica e os aspectos de ordenha de vacas com mastite em fazendas leiteiras com histórico de infecções mamárias clínicas. RESUMO causais países ambientais transmissão disso animais cenário etiológicos DEL (DEL 4273 4 273 4.27 porte Gerais Brasil 283/4.273 2834273 283 (283/4.27 6,6%, 66 6,6% , 6 6,6%) 190/4.273 1904273 190 (190/4.27 4,4%, 44 4,4% 4,4%) spp 112/4.273 1124273 112 (112/4.27 2,6% 26 2 95/4.273 954273 95 (95/4.27 2,2% 22 isolados 438 43 8 43,8 1.871/4.273 18714273 1 871 (1.871/4.273 Desses 698 69 69,8 1.306/1.871, 13061871 1.306/1.871 306 (1.306/1.871) 27 3 27,3 510/1.871 5101871 510 (510/1.871 29 9 2,9 55/1.871 551871 55 (55/1.871 leves graves respectivamente 10 leve etiológica clínicas 427 4.2 283/4.27 283427 28 (283/4.2 6,6 190/4.27 190427 19 (190/4.2 4,4 112/4.27 112427 11 (112/4.2 2,6 95/4.27 95427 (95/4.2 2,2 43, 1.871/4.27 1871427 87 (1.871/4.27 69, 1306187 1.306/1.87 30 (1.306/1.871 27, 510/1.87 510187 51 (510/1.87 2, 55/1.87 55187 5 (55/1.87 42 4. 283/4.2 28342 (283/4. 6, 190/4.2 19042 (190/4. 4, 112/4.2 11242 (112/4. 95/4.2 9542 (95/4. 1.871/4.2 187142 (1.871/4.2 130618 1.306/1.8 (1.306/1.87 510/1.8 51018 (510/1.8 55/1.8 5518 (55/1.8 283/4. 2834 (283/4 190/4. 1904 (190/4 112/4. 1124 (112/4 95/4. 954 (95/4 1.871/4. 18714 (1.871/4. 13061 1.306/1. (1.306/1.8 510/1. 5101 (510/1. 55/1. 551 (55/1. 283/4 (283/ 190/4 (190/ 112/4 (112/ 95/4 (95/ 1.871/4 1871 (1.871/4 1306 1.306/1 (1.306/1. 510/1 (510/1 55/1 (55/1 283/ (283 190/ (190 112/ (112 95/ (95 1.871/ 187 (1.871/ 130 1.306/ (1.306/1 510/ (510/ 55/ (55/ (28 (19 (11 (9 1.871 18 (1.871 13 1.306 (1.306/ (510 (55 (2 (1 ( 1.87 (1.87 1.30 (1.306 (51 (5 1.8 (1.8 1.3 (1.30 1. (1. (1.3

ABSTRACT: Bovine mastitis is the most impacting disease of dairy industry, and it is characterized by a complexity of causal agents, which have revealed a geographical variation among regions and countries. The mastitis-related pathogens have been traditionally classified as contagious or environmental, based on habits of the microorganisms and transmission routes. Besides, the severity of mammary infections has been associated with the virulence of the pathogens, and immune and nutritional status of the hosts. Considering this scenario, we investigated the etiological pattern, clinical severity scores, and days in milk (DIM) data in 4,273 clinical cases of bovine mastitis among ten large-dairy farms located in Brazil. Streptococcus dysgalactiae (283/4,273 = 6.6%), Escherichia coli (190/4,273 = 4.4%), Prototheca spp. (112/4,273 = 2.6%), and Streptococcus uberis (95/4,273 = 2.2%) were the predominant pathogens isolated. Among 4,273 clinical cases, clinical severity score was available in 43.8% (1,871/4,273) animals. From these, 69.8% (1,306/1,871), 27.3% (510/1,871), and 2.9% (55/1,871) were scored as mild, moderate, and severe, respectively. Pathogens were observed mainly in samples obtained during the first 100 days in milk, and clinical severity scored mainly as mild. Our results contributed to the etiological identification, clinical severity scoring, and milking aspects of mastitic cows in dairy farms with a history of clinical mammary infections. ABSTRACT industry agents countries mastitisrelated related environmental routes Besides hosts scenario pattern scores DIM (DIM 4273 4 273 4,27 largedairy large Brazil 283/4,273 2834273 283 (283/4,27 6.6%, 66 6.6% , 6 6.6%) 190/4,273 1904273 190 (190/4,27 4.4%, 44 4.4% 4.4%) spp 112/4,273 1124273 112 (112/4,27 2.6%, 26 2.6% 2 2.6%) 95/4,273 954273 95 (95/4,27 2.2% 22 isolated 438 43 8 43.8 1,871/4,273 18714273 1 871 (1,871/4,273 animals these 698 69 69.8 1,306/1,871, 13061871 1,306/1,871 306 (1,306/1,871) 27 3 27.3 510/1,871, 5101871 510/1,871 510 (510/1,871) 29 9 2.9 55/1,871 551871 55 (55/1,871 mild moderate severe respectively 10 identification scoring 427 4,2 283/4,27 283427 28 (283/4,2 6.6 190/4,27 190427 19 (190/4,2 4.4 112/4,27 112427 11 (112/4,2 2.6 95/4,27 95427 (95/4,2 2.2 43. 1,871/4,27 1871427 87 (1,871/4,27 69. 1306187 1,306/1,87 30 (1,306/1,871 27. 510187 510/1,87 51 (510/1,871 2. 55/1,87 55187 5 (55/1,87 42 4, 283/4,2 28342 (283/4, 6. 190/4,2 19042 (190/4, 4. 112/4,2 11242 (112/4, 95/4,2 9542 (95/4, 1,871/4,2 187142 (1,871/4,2 130618 1,306/1,8 (1,306/1,87 51018 510/1,8 (510/1,87 55/1,8 5518 (55/1,8 283/4, 2834 (283/4 190/4, 1904 (190/4 112/4, 1124 (112/4 95/4, 954 (95/4 1,871/4, 18714 (1,871/4, 13061 1,306/1, (1,306/1,8 5101 510/1, (510/1,8 55/1, 551 (55/1, 283/4 (283/ 190/4 (190/ 112/4 (112/ 95/4 (95/ 1,871/4 1871 (1,871/4 1306 1,306/1 (1,306/1, 510/1 (510/1, 55/1 (55/1 283/ (283 190/ (190 112/ (112 95/ (95 1,871/ 187 (1,871/ 130 1,306/ (1,306/1 510/ (510/1 55/ (55/ (28 (19 (11 (9 1,871 18 (1,871 13 1,306 (1,306/ (510/ (55 (2 (1 ( 1,87 (1,87 1,30 (1,306 (510 (5 1,8 (1,8 1,3 (1,30 (51 1, (1, (1,3

RESUMO O objetivo do trabalho foi caracterizar o índice de rendimento, o índice de rendimento de campo, a uniformidade e o ciclo de maturação de quinze genótipos de Coffea canephora cultivados em diferentes ambientes da Amazônia Ocidental. A pesquisa foi conduzida no Amazonas, em Itacoatiara e Manaus, e em Rondônia, em Porto Velho, Brasil. A interação entre genótipos x ambientes foi significativa, indicando que os clones apresentaram desempenho diferenciado entre os ambientes. A superioridade dos coeficientes genotípicos sobre aqueles de natureza ambiental sugere predominância dos efeitos genéticos na expressão dos índices de rendimento e da uniformidade de maturação. O índice de rendimento médio foi de 24,68% e o rendimento de campo de 22,57%, sendo o ambiente Itacoatiara com as maiores médias. A uniformidade de maturação de frutos teve uma média geral de 63,02%, com Porto Velho apresentando a maior uniformidade média (71,78%). A cultivar BRS1216 apresentou o melhor desempenho para os índices de rendimento e proporcionou maior ganho de seleção na média dos ambientes, apresentando adaptabilidade ampla para o índice de rendimento usual e adaptabilidade para ambientes favoráveis ao rendimento de campo. BRS3210 e BRS3220 se destacaram com mais 82% de uniformidade de maturação na média das localidades, porém a primeira com adaptabilidade para ambientes favoráveis e a segunda para ambiente desfavorável. BRS3220 também se destacou pela superioridade média para o rendimento de campo, exibindo ampla adaptabilidade e alta estabilidade fenotípica. Os clones avaliados apresentaram ciclos de maturação conforme o esperado. Ocidental Amazonas Manaus Rondônia Brasil significativa 2468 24 68 24,68 2257 22 57 22,57% médias 6302 63 02 63,02% 71,78%. 7178 71,78% . 71 78 (71,78%) BRS BRS121 BRS321 BRS322 82 localidades desfavorável fenotípica esperado 246 2 6 24,6 225 5 22,57 630 0 63,02 717 71,78 7 (71,78% BRS12 BRS32 8 24, 22,5 63,0 71,7 (71,78 BRS1 BRS3 22, 63, 71, (71,7 (71, (71 (7 (

ABSTRACT This study aimed to characterize the outturn index, field outturn index, uniformity of maturity, and maturation cycle of fifteen Coffea canephora genotypes grown in different environments of the Western Amazon. Conducted in Amazonas (Itacoatiara and Manaus) and Rondônia (Porto Velho), the research evaluated the performance of ten cultivars and five promising genotypes from Embrapa. The genotype × environment interaction was significant, indicating different performance of clones across environments. Genotypic coefficients surpassed environmental ones, indicating a genetic influence on outturn indices and uniformity of maturity. The mean outturn index was 24.68%, and the field outturn index was 22.57%, with Itacoatiara having the highest mean values. The overall mean fruit uniformity of maturity was 63.02%, with Porto Velho achieving the highest mean uniformity value (71.78%). The cultivar BRS1216 exhibited the best performance for outturn indices and provided the highest gain from selection across environments, showing wide adaptability for the outturn index and adaptability to environments favorable for field outturn. Cultivars BRS3210 and BRS3220 achieved more than 82% uniformity of maturity across locations, with BRS3210 adapting to favorable environments and BRS3220 adapting to unfavorable ones. Additionally, BRS3220 had a high mean field outturn index, indicating wide adaptability and high phenotypic stability. The evaluated Amazon Robusta clones and cultivars displayed the expected maturation cycles. Manaus Velho, , Velho) Embrapa significant ones 2468 24 68 24.68% 2257 22 57 22.57% values 6302 63 02 63.02% 71.78%. 7178 71.78% . 71 78 (71.78%) BRS BRS121 BRS321 BRS322 82 locations Additionally stability cycles 246 2 6 24.68 225 5 22.57 630 0 63.02 717 71.78 7 (71.78% BRS12 BRS32 8 24.6 22.5 63.0 71.7 (71.78 BRS1 BRS3 24. 22. 63. 71. (71.7 (71. (71 (7 (

Resumo Atécnica de vergamento da madeira por vaporização se apresenta como opção viável para projetos de estruturas curvilíneas, como as gridshells. Madeiras coníferas são comumente adotadas em estruturas de cobertura, pois além da desejada relação entre resistência mecânica e densidade, permitem o completo tratamento da seção transversal da peça. Entretanto, características como a predominância de alburno ou de cerne e a presença de defeitos são variáveis que afetam o desempenho estrutural. O objetivo deste estudo foi avaliar o limite de vergamento de lamelas de Acrocarpus flaxinifloius (cedro indiano) com raio de curvatura de 21 cm em diferentes espessuras. Também se investigou o impacto da predominância de alburno ou cerne e da presença de defeitos na força de vergamento. A literatura indica que a flexibilização plástica por vapor ocorre a 100°C, com 2,4 minutos para cada milímetro de espessura da lamela, parâmetros estes considerados neste estudo. A análise estatística indicou o limite de 8 mm de espessura para o vergamento das lamelas e a maior presença de alburno ou de cerne, bem como os defeitos da madeira, não afetou significativamente a força de vergamento. curvilíneas gridshells cobertura densidade peça Entretanto estrutural cedro indiano 2 espessuras 100C C 100 100°C 24 4 2, lamela 10 1

Abstract The technique of bending wood by vaporization presents itself as a viable option for curvilinear structural projects, such as gridshells. Coniferous woods are often used in roof structures because, in addition to the desired relationship between mechanical strength and density, they allow the complete treatment of the cross-section of the piece. However, characteristics such as the predominance of sapwood or heartwood and the presence of defects are variables that affect structural performance. The aim of this study was to evaluate the bending limit of Acrocarpus laxinifloius (Indian cedar) veneers with a bending radius of 21 cm at different thicknesses. The impact of the predominance of sapwood or heartwood and the presence of defects on the bending strength was also investigated. The literature indicates that plastic flexibilization by steam occurs at 100°C, with 2.4 minutes for each millimeter of lamella thickness, which were the parameters considered in this study. The statistical analysis indicated a thickness limit of 8 mm for the lamellae to bend and the greater presence of sapwood or heartwood, as well as wood defects, did not significantly affect the bending force. projects gridshells because density crosssection cross section piece However performance Indian cedar 2 thicknesses investigated 100C C 100 100°C 24 4 2. force 10 1

Resumo Introdução: Este estudo investigou variáveis associadas à mortalidade em receptores de transplante renal (RTR) diagnosticados com doença linfoproliferativa pós-transplante (PTLD, do inglês post-transplant lymphoproliferative disease) e viremia simultânea pelo vírus Epstein-Barr (EBV). Métodos: Estudo de coorte retrospectivo incluindo RTR diagnosticados com PTLD entre 2018 e 2020. Desfecho: óbito em até dois anos após diagnóstico. Resultados: Entre 1.625 RTR que realizaram coleta de viremia para EBV (por PCR, 2018–2020) por qualquer motivo, 238 (14,6%) apresentaram carga viral positiva e 41 (17,2%) PTLD simultânea. Esses 41 pacientes tinham em média 40,1 anos ao diagnóstico e 8,6 anos após o transplante; 26,8% foram induzidos com rATG e 92,7% foram mantidos com tacrolimus e azatioprina (TAC/AZA) como regime imunossupressor. Linfonodos (75,6%) foram o local mais comum de PTLD, seguidos pelo trato gastrointestinal (48,8%), com 61,0% no estágio IV de Lugano e 80,5% PTLD monomórfica. A carga viral média do EBV foi 12.198 UI/mL. A sobrevida dos pacientes em um e dois anos após o diagnóstico foi 60,4% e 46,8%, respectivamente. Na análise de regressão de Cox, a idade ao diagnóstico de PTLD (HR para cada ano = 1,039; p < 0,001) e a carga viral do EBV (HR para cada log = 1,695; p = 0,026) foram associadas ao risco de óbito. Conclusão: Este estudo sugere que, em pacientes predominantemente em uso de TAC/AZA, a PTLD com carga viral simultânea positiva para EBV é um evento tardio, e a pior sobrevida está associada à idade mais avançada e à carga viral de EBV no momento do diagnóstico. Introdução (RTR póstransplante pós (PTLD posttransplant post transplant disease EpsteinBarr Epstein Barr EBV. . (EBV) Métodos 201 2020 Desfecho Resultados 1625 1 625 1.62 PCR 2018–2020 20182020 motivo 23 14,6% 146 14 6 (14,6% 4 17,2% 172 17 2 (17,2% 401 40 40, 86 8 8, 268 26 26,8 927 92 7 92,7 TAC/AZA TACAZA TAC AZA (TAC/AZA imunossupressor 75,6% 756 75 (75,6% 48,8%, 488 48,8% , 48 (48,8%) 610 61 0 61,0 805 80 5 80,5 monomórfica 12198 12 198 12.19 UImL UI mL UI/mL 604 60 60,4 468 46 46,8% respectivamente Cox HR 1,039 1039 039 0,001 0001 001 1,695 1695 695 0,026 0026 026 Conclusão tardio (EBV 20 202 162 62 1.6 2018–202 2018202 14,6 (14,6 17,2 (17,2 26, 9 92, 75,6 (75,6 48,8 (48,8% 61, 80, 1219 19 12.1 60, 46,8 1,03 103 03 0,00 000 00 1,69 169 69 0,02 002 02 16 1. 2018–20 201820 14, (14, 17, (17, 75, (75, 48, (48,8 121 12. 46, 1,0 10 0,0 1,6 2018–2 20182 (14 (17 (75 (48, 1, 0, 2018– (1 (7 (48 ( (4

Abstract Introduction: This study investigated variables associated with mortality in kidney transplant recipients (KTRs) diagnosed with post-transplant lymphoproliferative disease (PTLD) and a simultaneous Epstein-Barr virus (EBV) viremia. Methods: This was a retrospective cohort study enrolling KTRs diagnosed with PTLD between 2018 and 2020. Outcome: death within two years after diagnosis. Results: Among 1,625 KTRs who collected EBV viremia (by PCR, 2018–2020) for any reason, 238 (14.6%) had a positive viral load and 41 (17.2%) simultaneous PTLD. These 41 patients were 40.1 years old at diagnosis and 8.6 years after transplantation; 26.8% were induced with rATG and 92.7% were maintained on tacrolimus and azathioprine (TAC/AZA) as immunosuppressive regimen. Lymph nodes (75.6%) was the most common site of PTLD, followed by the gastrointestinal tract (48.8%), with 61.0% at Lugano stage IV and 80.5% monomorphic PTLD. The mean EBV viral load was 12,198 IU/mL. One- and two-year patient survival post-diagnosis was 60.4% and 46.8%, respectively. In the Cox regression analysis, age at PTLD diagnosis (HR for each year = 1.039; p < 0.001) and EBV viral load (HR for each log = 1.695; p = 0.026) were associated with risk of death. Conclusion: This study suggests that in patients predominantly on TAC/AZA, PTLD with simultaneous EBV positive viral load is a late event, and worse survival is associated with older age and EBV viral load at diagnosis. Introduction (KTRs posttransplant post (PTLD EpsteinBarr Epstein Barr (EBV Methods 201 2020 Outcome Results 1625 1 625 1,62 PCR 2018–2020 20182020 reason 23 14.6% 146 14 6 (14.6% 4 17.2% 172 17 2 (17.2% 401 40 40. 86 8 8. transplantation 268 26 26.8 927 92 7 92.7 TAC/AZA TACAZA TAC AZA (TAC/AZA regimen 75.6% 756 75 (75.6% 48.8%, 488 48.8% , 48 (48.8%) 610 61 0 61.0 805 80 5 80.5 12198 12 198 12,19 IUmL IU mL IU/mL One twoyear postdiagnosis 604 60 60.4 468 46 46.8% respectively analysis HR 1.039 1039 039 0.001 0001 001 1.695 1695 695 0.026 0026 026 Conclusion event 20 202 162 62 1,6 2018–202 2018202 14.6 (14.6 17.2 (17.2 26. 9 92. 75.6 (75.6 48.8 (48.8% 61. 80. 1219 19 12,1 60. 46.8 1.03 103 03 0.00 000 00 1.69 169 69 0.02 002 02 16 1, 2018–20 201820 14. (14. 17. (17. 75. (75. 48. (48.8 121 12, 46. 1.0 10 0.0 1.6 2018–2 20182 (14 (17 (75 (48. 1. 0. 2018– (1 (7 (48 ( (4

Resumo Introdução: Pacientes com doença renal em estágio terminal (DRET) geralmente enfrentam uma rotina desafiadora de hemodiálise, restrições alimentares e diversos medicamentos, podendo afetar sua função hemodinâmica. Abordagens domiciliares, seguras e não farmacológicas, como a estimulação transcraniana por corrente contínua (ETCC), devem ser combinadas com tratamento convencional. Objetivo: Avaliar segurança e viabilidade da ETCC na pressão arterial e frequência cardíaca em pacientes com DRET em hemodiálise. Método: Estudo paralelo, randomizado, controlado por placebo. Foram incluídos pacientes em hemodiálise por mais de três meses. Os pacientes receberam dez sessões não consecutivas de ETCC de 2mA no córtex motor primário. Cada sessão durou 20 minutos. No início do estudo e após cada uma das dez sessões, a pressão arterial e frequência cardíaca dos pacientes foram medidas a cada hora durante quatro horas. Resultados: Trinta pacientes foram randomizados para grupo ativo ou sham. A diferença média entre grupos foi calculada como valor médio do grupo sham menos valor médio do grupo ativo. Apesar de não haver alterações estatísticas para todos os desfechos considerando as 10 sessões, encontramos diferenças entre os grupos para pressão arterial sistólica –10,93 (–29,1; 7,2), diastólica –3,63 (–12,4; 5,1) e média –6,0 (–16,3; 4,2) e frequência cardíaca 2,26 (–2,5; 7,1). Não encontramos eventos adversos graves. O grupo ativo apresentou valores maiores de pressão arterial em todos os pontos, enquanto a frequência cardíaca foi menor no grupo ativo. Conclusão: ETCC é segura e viável para pacientes com DRET submetidos à hemodiálise. Estudos futuros devem investigar se a ETCC pode potencialmente induzir um efeito hipotensor protetor durante a hemodiálise. Introdução (DRET medicamentos hemodinâmica domiciliares farmacológicas ETCC, , (ETCC) convencional Objetivo Método paralelo randomizado placebo meses mA primário 2 minutos horas Resultados 1 1093 93 –10,9 –29,1 291 29 (–29,1 7,2, 72 7,2 7 7,2) 363 3 63 –3,6 –12,4 124 12 4 (–12,4 5,1 51 5 60 6 0 –6, –16,3 163 16 (–16,3 4,2 42 226 26 2,2 –2,5 25 (–2,5 7,1. 71 7,1 . 7,1) graves pontos Conclusão (ETCC 109 9 –10, –29, (–29, 7, 36 –3, –12, (–12, 5, –6 –16, (–16, 4, 22 2, –2, (–2, –10 –29 (–29 –3 –12 (–12 – –16 (–16 –2 (–2 –1 (–1 (– (

Abstract Introduction: Patients with end-stage renal disease often face a challenging routine of hemodialysis, dietary restrictions, and multiple medications, which can affect their hemodynamic function. Home-based, safe, and nonpharmacological approaches such as transcranial direct current stimulation (tDCS) should be combined with conventional treatment. Objective: To assess the safety and feasibility of tDCS on blood pressure and heart rate in patients with end-stage renal disease undergoing hemodialysis. Method: This is a parallel, randomized, sham-controlled trial. Patients undergoing hemodialysis for more than three months were included. The patients received ten non-consecutive 2mA tDCS sessions on the primary motor cortex . Each session lasted 20 minutes. At baseline and after each of the ten sessions, blood pressure and heart rate of the patients were measured hourly for four hours. Results: Thirty patients were randomized to the active or sham group. The mean difference between the groups was calculated as the mean value of the sham group minus the mean value of the active group. Despite there were no statistical changes for all outcomes considering all 10 sessions, we found differences between groups for systolic –10.93 (–29.1;7.2), diastolic –3.63 (–12.4; 5.1), and mean blood pressure –6.0 (–16.3; 4.2) and hear rate 2.26 (–2.5; 7.1). No serious adverse events were found. The active group showed higher blood pressure values at all points, while heart rate was lower in the active group. Conclusion: tDCS is safe and feasible for patients with end-stage renal disease undergoing hemodialysis. Future studies should investigate whether tDCS could potentially induce a hypotensive protective effect during hemodialysis. Introduction endstage end stage restrictions medications function Homebased, Homebased Home based, based Home-based (tDCS treatment Objective Method parallel shamcontrolled controlled trial included nonconsecutive non consecutive mA 2 minutes hours Results 1 1093 93 –10.9 –29.17.2, 29172 –29.1 7.2 , 29 7 (–29.1;7.2) 363 3 63 –3.6 –12.4 124 12 4 (–12.4 5.1, 51 5.1 5 5.1) 60 6 0 –6. –16.3 163 16 (–16.3 4.2 42 226 26 2.2 –2.5 25 (–2.5 7.1. 71 7.1 7.1) points Conclusion 109 9 –10. 17 –29.17.2 2917 291 –29. 72 7. (–29.1;7.2 36 –3. –12. (–12. 5. –6 –16. (–16. 4. 22 2. –2. (–2. –10 –29.17. –29 (–29.1;7. –3 –12 (–12 – –16 (–16 –2 (–2 –1 –29.17 (–29.1;7 (–1 (– (–29.1; ( (–29.1 (–29. (–29

Abstract Objective Evaluate the level of information of pediatricians about the diagnosis and management of cryptorchidism. Method A cross-sectional observational study was conducted using a form via the "Google Forms" platform. The study population included pediatricians and pediatric residents associated with the Brazilian Society of Pediatrics. Seven hundred twenty-eight responses were recorded and analyzed using IBM SPSS v21. Results 728 valid responses were obtained. Of these answers, only 20.5 % answered that the physical examination was sufficient for the diagnosis, and 79.4 % responded that they requested ultrasound as the best test to aid in diagnosing cryptorchidism. When questioned about the ideal age for referring a patient with cryptorchidism, the survey recorded 56.3 % of the responses defending the correct age as six months old, 30.2 % shortly after birth, and 13.2 % at two years old. Other topics were addressed in the form, such as the frequency of evaluation of testicular position and investigation for DDS, among others. Still, the answers to these questions were compatible with current manuals and guidelines on cryptorchidism. Conclusion It is evident that the understanding of the professionals consulted about the diagnosis and management of cryptorchidism needs to be updated with the current practices adopted and that pediatricians, in general, must maintain periodic programs on this subject. Therefore, this topic should be part of a continuing education program with pediatric surgery. crosssectional cross sectional Google Forms platform Pediatrics twentyeight twenty eight v21 v 72 obtained 205 20 5 20. 794 79 4 79. 563 56 3 56. old 302 30 2 30. birth 132 13 13. DDS others Still general subject Therefore surgery v2 7 1

Resumen Este estudio tiene como objetivo presentar la interseccionalidad en el campo de la Bibliotecología de la mano de la intelectual afroamericana Patrícia Hill Collins. También busca reflexionar sobre cómo esta teoría social crítica y herramienta analítica puede dialogar con el ámbito bibliotecario, permitir que este campo desarrolle visiones más críticas en relación con el mundo social. Esta visión está en línea con lo que han señalado los teóricos en el campo, en diferentes contextos históricos, que señalaba la presencia de la ideología de la clase dominante en la constitución y mantenimiento de un conocimiento único, influir en el trabajo de los bibliotecarios, forjar un enfoque conservador y excluyente, principalmente en las bibliotecas, lo que incide e influye en las relaciones entre este espacio, este profesional y la sociedad. Como metodología es básica, de carácter exploratorio y tiene un enfoque cualitativo. De los resultados presentados, se desprende que el posicionamiento político de los autores destacados en este texto reforzó la necesidad de construir una agenda basada en los derechos humanos, la justicia social, racial, de género y epistémica, con el objetivo de minimizar los daños causados por las relaciones de poder y la lucha de clases, que aún es reproducida por la clase bibliotecaria en sus espacios de actividad. Por lo tanto, es necesario establecer una Bibliotecología brasileña interseccional (teoría y práctica), que actúe estrechamente alineada con las demandas sociales y políticas presentes en el contexto social, resaltando nuevos conocimientos y nuevos saberes, en busca de equidad y justicia social.

Resumo Este estudo tem como objetivo buscar apresentar ao campo da biblioteconomia a interseccionalidade a partir da intelectual afro-americana Patrícia Hill Collins. Busca também refletir como essa teoria social crítica e ferramenta analítica pode dialogar com o campo biblioteconômico, possibilitando que esse campo desenvolva olhares mais críticos em relação ao mundo social. Essa visão vai ao encontro do que foi apontada por teóricos da área, em diferentes contextos históricos, que sinalizaram a presença da ideologia da classe dominante na constituição e manutenção de um único saber, influenciando na atuação das pessoas bibliotecárias, forjando uma atuação conservadora e excludente, principalmente nas bibliotecas, o que afeta e influência nas relações entre esse espaço, esse profissional e a sociedade. Como metodologia, é de natureza básica, exploratória e de abordagem qualitativa. A partir dos resultados apresentados, percebe-se que o posicionamento político dos autores evidenciados nesse texto reforçou a necessidade de construir-se uma agenda pautada pelos direitos humanos, por justiça social, racial, de gênero e epistêmica, visando minimizar os danos causados pelas relações de poder e pela luta de classes e que é ainda reproduzido pela classe bibliotecária nos seus espaços de atuação. Assim, é necessário instituir uma biblioteconomia brasileira interseccional (teoria e prática), que atue alinhada estreitamente às demandas sociais e políticas presentes no contexto social, evidenciando novos saberes e novos conhecimentos, em busca da equidade e da justiça social.

Abstract This study seeks to present the intersectionality to the field of Library Science from the African-American intellectual Patrícia Hill Collins and reflect on how this critical social theory and analytical tool can dialogue with the library science field, enabling this field to develop more critical views in relation to the world social, since in different historical contexts, theorists in the area have pointed out the presence of the ideology of the dominant class in the constitution and maintenance of a single knowledge, influencing the actions of librarians, forging a conservative and exclusionary action, especially in libraries, which affects and influences in the relationships between this space, this professional and society. As a methodology, it is a basic, exploratory and a qualitative study. From the results presented, it is clear that the political positioning of the authors highlighted in this text reinforced the need to build an agenda based on human rights, social, racial, gender and epistemic justice, aiming to minimize the damage caused by power relations and class struggle and which is still reproduced by the librarian class in their spaces of activityit. It is necessary to establish an intersectional Brazilian Library Science (theory and practice), which acts closely aligned with the social and political demands present in the social context, highlighting new knowledge and knowledge, in search of equity and social justice.