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Abstract Introduction: Osteoporosis (OP) is the most frequent metabolic bone disease, associated with fragility fractures and increased morbimortality. Despite population aging, there has been a downward trend in the implementation of anti-osteoporotic therapy. Objectives: To determine the therapeutic inertia in OP in postmenopausal women in primary health care. Verify whether age, T-score, the FRAX value, and anti-osteoporotic therapeutic inertia are associated. Methods: Cross-sectional observational study. Inclusion criteria: women aged between 55 and 85 coded with OP (ICPC-2 - L95) or fractures (ICPC-2 - L72-76) in the list of problems. A simple random sample was selected. Therapeutic inertia was defined based on the Portuguese Society of Rheumatology recommendations. Results: A sample of 217 patients was obtained. Therapeutic inertia was found in 17.5% of women, which increased to 48.6% in those who suffered fractures (p<0.001). There was a statistically significant difference between the ages of patients with and without therapeutic inertia (77.5 vs 73.0, p<0.010). The median FRAX for major osteoporotic fracture (16.5 vs 9.65, p<0.001) and hip fracture (7.6 vs 3.3, p<0.001) was higher in the group with therapeutic inertia. The difference between T-score values for the lumbar spine (2.45 vs 2.71) and the femoral neck (2.07 vs 2.02) did not reach statistical significance (p=0.299). Conclusion: This study highlights the application of the most recent national guidelines regarding osteoporosis treatment in the studied health care unit, but underlines the need for broader intervention in osteoporosis-related fractures and at older ages.

Resumo Introdução: A osteoporose (OP) é a doença óssea metabólica mais frequente, associando-se a fraturas de fragilidade e aumento de morbimortalidade. Apesar do envelhecimento populacional tem-se verificado uma tendência decrescente na implementação de terapêutica antiosteoporótica. Objetivos: Determinar a inércia terapêutica na OP em mulheres pós-menopáusicas ao nível dos cuidados de saúde primários. Verificar se existe associação entre a idade dos utentes, o T-score e o valor de FRAX e a inércia terapêutica antiosteoporótica. Métodos: Estudo observacional transversal. Critérios de inclusão: mulheres com idades entre os 55 e os 85 anos codificadas com OP (ICPC-2 - L95) ou fraturas (ICPC-2 - L72-76) na lista de problemas. Foi selecionada uma amostra aleatória simples. A inércia terapêutica foi definida com base nas recomendações da Sociedade Portuguesa de Reumatologia. Resultados: Obteve-se uma amostra de 217 utentes. Apurou-se inércia terapêutica em 17,5% das mulheres, valor que aumenta para 48,6% nas que sofreram fraturas (p<0,001). As idades diferem de forma estatisticamente significativa entre os utentes com e sem inércia terapêutica (77,5 vs 73,0, p<0,010). A mediana do FRAX para fratura osteoporótica major (16,5 vs 9,65, p<0,001) e fratura da anca (7,6 vs 3,3, p<0,001) foi superior no grupo com inércia terapêutica. Os valores de T-score da coluna lombar (2,45 vs 2,71) e do colo do fémur (2,07 vs 2,02) não diferiram de forma estatisticamente significativa (p=0,299). Conclusão: Este estudo realça a aplicação da evidência mais atual ao nível do tratamento da OP na unidade estudada, mas salienta a necessidade de maior intervenção na OP fraturária e em idades mais avançadas.

https://doi.org/10.32385/rpmgf.v40i5.13974

Causalidade entre a gravidade da disfagia e os seus fatores determinantes
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Escudeiro, Maria Francisca

; Carvalho, Isabel Maria da Silva

Revista Portuguesa Otorrinolaringologia e Cirurgia de Cabeça e Pescoço

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sep 2024, Volume 62 N. 3 Pages 211 - 222

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Objetivos: caracterizar, do ponto de vista sociodemográfico e clínico, os doentes submetidos a videoendoscopia da deglutição que, no decurso do seu internamento, apresentaram quadro de disfagia orofaríngea; encontrar estratégias para melhorar a qualidade da resposta aos doentes que necessitem de recorrer a videoendoscopia da deglutição. Desenho do Estudo: este estudo tem por base uma amostra recolhida no Centro Hospitalar Universitário Santo António, entre janeiro de 2019 e setembro de 2021, inclusive. Material e Métodos: foram analisados retrospetivamente os processos clínicos e estudos imagiológicos de 157 doentes. Após seleção cuidada, foram excluídos do estudo todos os casos que não cumpriram os critérios de inclusão. Assim, obtiveram-se para análise 143 doentes. Resultados e Conclusões: este estudo identifica fatores determinantes da variabilidade do nível FOIS, detetando doentes graves numa fase preliminar, pré-VED, diminuindo o tempo de espera em mais de 70%, e, consequentemente, melhorando a qualidade do serviço em todas as suas dimensões.

Abstract Objectives: characterize, in a sociodemographic and clinical perspective, pacients who underwent videoendoscopy of swallowing and had oropharyngeal dysphagia during their hospital stay. Furthermore, it is also intended to find strategies to improve the quality of the response to pacientes in need of videoendoscopy of swallowing. Case study: this study is based on a sample collected in Centro Hospitalar Universitário Santo António, between january 2019 and september 2021, including. Materials and Methods: the clinical data and image studies from 157 pacients were retrospectively analyzed. After careful selection, all cases that did not meet the inclusion criteria were excluded from the study. Thus, 143 patients were selected for analysis. Results and conclusions: this study identifies determining factors of FOIS level variability, detecting severe patients in a preliminary, pre-VED phase, reducing waiting time by over 70%, and consequently improving service quality in all its dimensions.

https://doi.org/10.34631/sporl.2097

Portuguese Results of the ETICC Study: Impact of the Pandemic COVID-19 in the Diagnosis and Management of Colorectal Cancer in 2020 in Portuguese Hospitals
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Rafael, Maria Ana

; Sequeira, Cristiana

; Barros, Sónia Isabel da Silva

; Abreu, Bárbara Silva

; Teixeira, Cristina

; Lahmek, Pierre

; Besnard, Marine

; Lesgourgues, Bruno

GE-Portuguese Journal of Gastroenterology

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aug 2024, Volume 31 N. 4 Pages 32 - 37

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Introdução: A pandemia provocada pelo coronovírus (COVID-19) condicionou a prática clínica de múltiplas formas, incluindo a restrição a exames endoscópicos não urgentes. Por este motivo, decidimos avaliar o im-pacto do primeiro ano de pandemia no diagnóstico e tratamento do cancro colorretal (CCR) em Portugal. Métodos: Este é um subestudo do estudo Francês retrospetivo multicêntrico ETICC (Etude de l’Impact de la pandémie COVID-19 sur le diagnostic et la prise en charge du Cancer Colorectal). Foram comparadas as características dos doentes, manifestações clínicas, estadiamento do CCR ao diagnóstico, intervalos entre primeiro contacto médico neste contexto, diagnóstico histológico e tratamentos, entre o primeiro ano de pandemia e o ano precedente. Resultados: Foram incluídos 766 doentes, 496 no grupo controlo e 270 no grupo COVID. Em França e em Portugal não se veriﬁcou um agravamento no estadiamento do CCR à data do diagnóstico no primeiro ano de pandemia, com 21% dos casos metastáticos à data de diagnóstico no grupo controlo e 22% no primeiro ano da pandemia (p = 0.770). Contudo, apenas em Portugal se constatou uma redução signiﬁcativa do número de CCR em doentes assintomáticos (25% para 8.4%; p < 0.001) ou após uma pesquisa de sangue oculto positiva (20.8% para 11.3%; p = 0.002) durante a pandemia. Apesar do aumento na taxa de complicações ao diagnóstico não ser signiﬁcativa, em Portugal a taxa de diagnósticos em contexto de oclusão intestinal aumentou signiﬁcativamente (12.1% para 18.1%; p = 0.033). Em Portugal, o tempo entre início dos sintomas e a primeira consulta médica aumentou signiﬁcativamente, de uma mediana de 50 para 64 dias durante o COVID (p < 0.001). Por outro lado, o tempo entre diagnóstico histológico e resseção tumoral reduziu signiﬁcativamente de 65 para 39 dias (p < 0.001). O tempo entre diagnóstico histológico e tratamento neoadjuvante (mediana de 64 para 67 dias; p = 0.590) ou quimioterapia paliativa (mediana de 50 para 51 dias; p = 1.000) não foi estatisticamente signiﬁcativo, tendo decrescido signiﬁcativamente o tempo entre resseção e adjuvância (mediana de 54 para 43 dias, p = 0.001). Discussão: Este estudo evidenciou um impacto signiﬁcativo no diagnóstico de CCR durante o primeiro ano de pandemia, mais pronunciado que em França. Este achado dever-se-á não só à limitação do acesso aos exames endoscópicos, mas também à diﬁculdade da população portuguesa em aceder aos Cuidados de Saúde Primários. Por outro lado, tanto em França como em Portugal, no primeiro ano de pandemia não se veriﬁcou um agravamento no estadiamento ou atraso no tratamento médico e cirúrgico do CCR.

Abstract Introduction: The outbreak of coronavirus disease 2019 (COVID-19) had affected clinical practice in several ways, including the restriction of nonessential endoscopic procedures. Therefore, our aim was to evaluate how colorectal cancer (CRC) diagnosis and management was affected during the ﬁrst year of pandemics in Portugal. Methods: This is a Portuguese substudy of the French retrospective multicentric study ETICC (Etude de l’Impact de la pandémie COVID-19 sur le diagnostic et la prise en charge du Cancer Colorectal). We compared patients’ characteristics, clinical manifestations, CRC staging at diagnosis, delay to ﬁrst medical appointment, histological diagnosis, surgical and medical treatments between the year previous to the pandemics (control) and the ﬁrst year of pandemics. Results: We included 766 patients: 496 in the control group and 270 in the COVID group. There was no signiﬁcant difference in CRC staging at diagnosis between both groups, with 21% being diagnosed as metastatic in the control group and 22% in the ﬁrst year of pandemics (p = 0.770). Contrary to what happened in France, there was a signiﬁcant decrease in CRC diagnosis in asymptomatic patients (25-8.4%; p < 0.001) and after a positive fecal immunochemical test (20.8-11.3%; p = 0.002) during the pandemics. Although the increase in the overall complication rate at diagnosis was nonsigniﬁcant, in Portugal, there was a signiﬁcant increase in diagnosis of abdominal occlusion (12.1-18.1%; p = 0.033). In Portugal, time between the beginning of symptoms and the ﬁrst medical appointment signiﬁcantly increased from a median of 50 days to 64 days during COVID (p < 0.001). On the contrary, time between histological diagnosis and tumor resection had signiﬁcantly decreased from a median of 65 to 39 days (p < 0.001). Time between histological diagnosis and neo-adjuvant treatment was not statistically different (median of 64-67 days; p = 0.590), as was time between histological diagnosis and palliative chemotherapy (median of 50-51 days; p = 1.000). Time from CRC resection and adjuvant treatment has signiﬁcantly decreased from a median of 54 to 43 days (p = 0.001). Discussion: We found a signiﬁcant impact in CRC diagnosis in the ﬁrst year of pandemics, more pronounced than what was found in France. These are likely related not only with the closing of endoscopy units but also with the difﬁculties patients had in ﬁnding an appointment with their general practitioners. On the other hand, both in France and Portugal, the ﬁrst year of pandemics did not worsen CRC staging at diagnosis and did not signiﬁcantly affect medical and surgical treatments once the diagnosis was made.

https://doi.org/10.1159/000531234

Causalidade e Gravidade das Reações Adversas e Alterações Laboratoriais ao Tratamento com Benznidazol em Pacientes com Doença de Chagas Crônica
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Belmino, Alanna Carla da Costa

; Sousa, Emanuela Kelly Silva

; Silva Filho, José Damião da

; Rocha, Eduardo Arrais

; Nunes, Francisca Mylena Melgaço

; Sampaio, Tiago Lima

; Evangelista, Leones Fernandes

; Duque, Bruna Ribeiro

; Araújo, Isabel Cristina da Silva

; Jacó, José Igor de Oliveira

; Oliveira, Maria de Fátima

Arquivos Brasileiros de Cardiologia

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aug 2024, Volume 121 N. 8 elocation e20230787

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Fundamento A Doença de Chagas (DC) representa um grave problema de saúde pública na América Latina. O Benznidazol (BNZ) é utilizado para o tratamento DC e, apesar do seu amplo uso, poucas informações estão disponíveis sobre sua toxicidade e mecanismos das Reações Adversas ao Medicamento (RAM). Objetivos Identificar e classificar as reações adversas clínicas e laboratoriais ocasionadas pelo uso do BNZ quanto à sua causalidade e gravidade. Métodos Estudo de coorte prospectivo realizado no período de janeiro de 2018 a dezembro de 2021. O acompanhamento do tratamento incluiu consultas e análises laboratoriais antes, 30 e 60 dias após o início do tratamento. As RAM foram classificadas quanto à causalidade e gravidade. Na análise estatística o nível de significância adotado foi p<0,05. Resultados Participaram do estudo 40 pacientes com DC crônica, observou-se alta prevalência de RAM com um total de 161 em 30 (90%) pacientes. Destas, 104 (64,6%) foram classificadas como possíveis e 57 (35,4%) como prováveis. As reações foram classificadas em moderadas e leves. Dos 40 pacientes, nove (22,5%) suspenderam o tratamento. As RAM associadas à interrupção e intervenções foram as que afetaram o sistema dermatológico, sistema nervoso central e periférico ou que culminaram em ageusia. Após 30 dias de tratamento, alterações hematológicas e bioquímicas leves foram observadas como linfopenia. Conclusão Apesar do elevado percentual de RAM, muitos pacientes foram capazes de completar o tratamento, o que se atribui ao êxito da estratégia de acompanhamento com intervenções de tratamento sintomático juntamente ao aconselhamento, levando à compreensão da sintomatologia e manutenção do tratamento. (DC Latina (BNZ RAM. . (RAM) gravidade 201 2021 antes 3 6 p005 p 0 05 p<0,05 4 crônica observouse observou 16 90% 90 (90% Destas 10 64,6% 646 64 (64,6% 5 35,4% 354 35 (35,4% prováveis 22,5% 225 22 (22,5% dermatológico ageusia linfopenia aconselhamento (RAM 20 202 p00 p<0,0 1 9 (90 64,6 (64,6 35,4 (35,4 22,5 2 (22,5 p0 p<0, (9 64, (64, 35, (35, 22, (22, p<0 ( (64 (35 (22 p< (6 (3 (2

Abstract Background Chagas disease (CD) is a serious public health problem in Latin America. Benznidazole (BNZ) is used for the treatment of CD and, despite its wide use, little information is available about its toxicity and mechanisms of adverse drug reactions (ADR). Objectives To identify and classify clinical and laboratory adverse reactions caused by BNZ in terms of causality and severity. Methods Prospective cohort study from January 2018 to December 2021. Treatment follow-up included visits and biochemical tests (complete blood count, liver and kidney function tests) before, during and after treatment. ADR were classified according to causality and severity. In the statistical analysis, the significance level was set at p<0.05. Results Forty patients with chronic CD were included. A high prevalence of ADR was observed 161 ADR in 30 patients [90%]; of these, 104 (64.6%) were classified as possible and 57 (35.4%) as probable. The ADR were classified as moderate and mild. Of the 40 patients, nine (22.5%) discontinued treatment. ADR associated with treatment discontinuation and interventions were those that affected the dermatological system, central and peripheral nervous system and sense organs such as ageusia. Mild hematological and biochemical changes such as lymphopenia were observed after 30 days of treatment. Conclusion Many patients were able to complete the treatment even with ADR, which can be attributed to the successful follow-up strategy with symptomatic treatment and counseling, leading to patient’s awareness of symptoms and treatment adherence. (CD America (BNZ use ADR. . (ADR) severity 201 2021 followup follow up count before analysis p005 p 0 05 p<0.05 16 3 90% 90 [90%] these 10 64.6% 646 64 6 (64.6% 5 35.4% 354 35 4 (35.4% probable mild 22.5% 225 22 (22.5% ageusia counseling patient s adherence (ADR 20 202 p00 p<0.0 1 9 [90% 64.6 (64.6 35.4 (35.4 22.5 2 (22.5 p0 p<0. [90 64. (64. 35. (35. 22. (22. p<0 [9 (64 (35 (22 p< [ (6 (3 (2 (

https://doi.org/10.36660/abc.20230787

Geography and public health: analysis of the epidemiological dynamics of meningitis in Brazil, between 2010 and 2019
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Silva, Luis Roberto da

; Arruda, Laís Eduarda Silva de

; Barreto, Isabel de Jesus Brandão

; Aragão, João Victor Rodrigues de

; Silva, Maria Luiza Ferreira Imburana da

; Lira, Guilherme

; Teixeira, Camila Maria Barros

; Oliveira, Emília Carolle Azevedo de

Revista Brasileira de Epidemiologia

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2024, Volume 27 elocation e240031

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

https://doi.org/10.1590/1980-549720240031

Distribuição de óbitos devido ao câncer do colo do útero nos municípios de extrema pobreza, Brasil, 2000 a 2018 pobreza Brasil 200 201 20 2
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Nascimento, Maria Isabel do

; Silva, Esther Rohem Costa

; Flauzino, Regina Fernandes

Cadernos Saúde Coletiva

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2024, Volume 32 N. 1 elocation e32010444

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Introdução: O câncer do colo uterino (CCU) permanece uma importante causa de morte nas regiões mais pobres do mundo. Objetivo: Analisar tendências da distribuição relativa de óbitos por CCU ocorridos nos municípios de extrema pobreza (EP) do Brasil, de 2000 a 2018. Método: A distribuição relativa de óbitos por CCU nos municípios de EP foi avaliada em relação ao total de óbitos observados em cada Unidade Federativa (UF). Uma modelagem autorregressiva foi usada para avaliar as tendências temporais da distribuição relativa de óbitos de 2000 a 2018. Resultados: De 2000 a 2018, houve 94.065 óbitos por CCU no Brasil, e 10,7% deles ocorreram nos municípios de EP. Seis estados (Amazonas, Roraima, Pará, Amapá, Tocantins e Mato Grosso do Sul) tiveram 100% dos seus municípios de EP reportando a ocorrência desses óbitos. As tendências na distribuição de óbitos nos municípios de EP em relação ao total de óbitos de cada UF seguiram em elevação em onze estados brasileiros. Conclusões: O CCU é doença prioritária das políticas públicas do Brasil, e as tendências desses óbitos observadas nos municípios mais pobres apontam que mais atenção deve ser dada a estas unidades de análise, a fim de melhorar a saúde das pessoas mais pobres. Introdução (CCU mundo Objetivo (EP Brasil 200 2018 Método UF. . (UF) Resultados 94065 94 065 94.06 107 10 7 10,7 Amazonas, Amazonas (Amazonas Roraima Pará Amapá Sul 100 brasileiros Conclusões análise 20 201 (UF 9406 9 06 94.0 1 10, 2 940 0 94.

Abstract Background: Cervical cancer (CC) remains a major cause of death in the poorest regions of the world. Objective: To analyze trends in relative distribution of CC deaths occurred in extreme poverty municipalities, Brazil, from 2000 to 2018. Method: The relative distribution of CC deaths occurred in extreme poverty municipalities was evaluated in relation to total number of CC deaths observed in each Federative Unit (FU). An autoregressive modeling was used to assess the temporal trends in the death distribution, 2000-2018. Results: From 2000 to 2018, there were 94,065 CC deaths, and 10.7% of them were recorded in extreme poverty municipalities. There were six states (Amazonas, Roraima, Pará, Amapá, Tocantins, and Mato Grosso do Sul) with 100.0% of extreme poverty municipalities reporting the occurrence of these deaths. The trends of death distribution in extreme poverty municipalities in relation to the total of deaths in each FU followed in increasing trends in eleven Brazilian FU. Conclusions: CC is a disease prioritized by public policies in Brazil, and the trends of these deaths observed in the poorest municipalities point out that more attention should be given to these units of analysis, in order to improve the health of the poorest people. Background (CC world Objective Brazil 200 2018 Method . (FU) 20002018. 20002018 2000-2018 Results 94065 94 065 94,06 107 10 7 10.7 Amazonas, Amazonas (Amazonas Roraima Pará Amapá Tocantins Sul 1000 100 0 100.0 Conclusions analysis people 20 201 (FU 2000201 2000-201 9406 9 06 94,0 1 10. 100. 2 200020 2000-20 940 94, 20002 2000-2 2000-

https://doi.org/10.1590/1414-462x202432010444

Diretrizes Brasileiras de Medidas da Pressão Arterial Dentro e Fora do Consultório – 2023 202 20 2
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Feitosa, Audes Diogenes de Magalhães

; Barroso, Weimar Kunz Sebba

; Mion Junior, Decio

; Nobre, Fernando

; Mota-Gomes, Marco Antonio

; Jardim, Paulo Cesar Brandão Veiga

; Amodeo, Celso

; Oliveira, Adriana Camargo

; Alessi, Alexandre

; Sousa, Ana Luiza Lima

; Brandão, Andréa Araujo

; Pio-Abreu, Andrea

; Sposito, Andrei C.

; Pierin, Angela Maria Geraldo

; Paiva, Annelise Machado Gomes de

; Spinelli, Antonio Carlos de Souza

; Machado, Carlos Alberto

; Poli-de-Figueiredo, Carlos Eduardo

; Rodrigues, Cibele Isaac Saad

; Forjaz, Claudia Lucia de Moraes

; Sampaio, Diogo Pereira Santos

; Barbosa, Eduardo Costa Duarte

; Freitas, Elizabete Viana de

; Cestario, Elizabeth do Espirito Santo

; Muxfeldt, Elizabeth Silaid

; Lima Júnior, Emilton

; Campana, Erika Maria Gonçalves

; Feitosa, Fabiana Gomes Aragão Magalhães

; Consolim-Colombo, Fernanda Marciano

; Almeida, Fernando Antônio de

; Silva, Giovanio Vieira da

; Moreno Júnior, Heitor

; Finimundi, Helius Carlos

; Guimarães, Isabel Cristina Britto

; Gemelli, João Roberto

; Barreto-Filho, José Augusto Soares

; Vilela-Martin, José Fernando

; Ribeiro, José Marcio

; Yugar-Toledo, Juan Carlos

; Magalhães, Lucélia Batista Neves Cunha

; Drager, Luciano F.

; Bortolotto, Luiz Aparecido

; Alves, Marco Antonio de Melo

; Malachias, Marcus Vinícius Bolívar

; Neves, Mario Fritsch Toros

; Santos, Mayara Cedrim

; Dinamarco, Nelson

; Moreira Filho, Osni

; Passarelli Júnior, Oswaldo

; Vitorino, Priscila Valverde de Oliveira

; Miranda, Roberto Dischinger

; Bezerra, Rodrigo

; Pedrosa, Rodrigo Pinto

; Paula, Rogerio Baumgratz de

; Okawa, Rogério Toshiro Passos

; Póvoa, Rui Manuel dos Santos

; Fuchs, Sandra C.

; Lima, Sandro Gonçalves de

; Inuzuka, Sayuri

; Ferreira-Filho, Sebastião Rodrigues

; Fillho, Silvio Hock de Paffer

; Jardim, Thiago de Souza Veiga

; Guimarães Neto, Vanildo da Silva

; Koch, Vera Hermina Kalika

; Gusmão, Waléria Dantas Pereira

; Oigman, Wille

; Nadruz Junior, Wilson

Arquivos Brasileiros de Cardiologia

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2024, Volume 121 N. 4 elocation e20240113

Abstract: Pt | Text: Pt | PDF: Pt

https://doi.org/10.36660/abc.20240113

Geography and public health: analysis of the epidemiological dynamics of meningitis in Brazil, between 2010 and 2019 health Brazil 201 20 2
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Silva, Luis Roberto da

; Arruda, Laís Eduarda Silva de

; Barreto, Isabel de Jesus Brandão

; Aragão, João Victor Rodrigues de

; Silva, Maria Luiza Ferreira Imburana da

; Lira, Guilherme

; Teixeira, Camila Maria Barros

; Oliveira, Emília Carolle Azevedo de

Revista Brasileira de Epidemiologia

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2024, Volume 27 elocation e240031

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Objetivo: Analisar a dinâmica epidemiológica espaçotemporal das meningites no Brasil, entre os anos de 2010 e 2019. Métodos: Estudo ecológico descritivo com os casos e óbitos por meningites no Brasil (2010–2019) no Sistema de Informações de Agravos de Notificação. Realizaram-se (I) análises de frequências dos casos e óbitos, taxas de prevalência, mortalidade, letalidade, testes de exato de Fisher e qui-quadrado; (II) regressão de Prais-Winsten; e (III) índice de Moran global, local e densidade de Kernel. Resultados: Notificaram-se 182.126 casos de meningites no Brasil, dos quais 16.866 (9,26%) evoluíram para óbito, com taxas de prevalência de 9,03/100.000/habitantes, mortalidade de 0,84/100.000/habitantes e letalidade de 9,26%. Destaca-se a tendência de decrescimento das taxas de prevalência (−9,5%, intervalo de confiança de 95% — IC95% −13,92; −4,96, p<0,01) e mortalidade (−11,74%, IC95% −13,92; −9,48, p<01,01), enquanto a letalidade se manteve estacionária (−2,08%, IC95% −4,9; 0,8; p<0,1941). A maioria dos casos foi de meningites virais (45,7%), entre 1 e 9 anos (32,2%), enquanto a maior parcela dos óbitos foi por meningites bacterianas (68%), entre 40 e 59 anos (26,3%). Nos mapas de Moran e Kernel das taxas de prevalência e mortalidade, destacaram-se com altas taxas os municípios do sul, sudeste e a capital de Pernambuco, no nordeste; já na letalidade, evidenciaram-se o norte, o nordeste e o litoral do sudeste. Conclusão: Encontrou-se decréscimo dos casos e óbitos por meningites neste estudo, entretanto a taxa de letalidade foi maior em áreas com menor prevalência, reforçando a necessidade do aprimoramento das ações de identificação, vigilância e assistência em saúde dos casos, bem como da ampliação da cobertura vacinal. Objetivo 201 2019 Métodos 2010–2019 20102019 (2010–2019 Notificação Realizaramse Realizaram I (I quiquadrado qui quadrado qui-quadrado II (II PraisWinsten Prais Winsten Prais-Winsten III (III global Resultados Notificaramse Notificaram 182126 182 126 182.12 16866 16 866 16.86 9,26% 926 26 (9,26% óbito 903100000habitantes habitantes 03 100 000 9,03/100.000/habitantes 084100000habitantes 0 84 Destacase Destaca −9,5%, 95 5 (−9,5% IC95 IC −13,92 1392 13 92 496 4 96 −4,96 p<0,01 p001 p 01 −11,74%, 1174 11 74 (−11,74% 948 48 −9,48 p<01,01, p0101 p<01,01 , p<01,01) −2,08%, 208 2 08 (−2,08% −4,9 49 0,8 8 p<0,1941. p01941 p<0,1941 . 1941 p<0,1941) 45,7%, 457 45,7% 45 7 (45,7%) 32,2%, 322 32,2% 32 (32,2%) 68%, 68 68% (68%) 26,3%. 263 26,3% 3 (26,3%) destacaramse destacaram sul Pernambuco evidenciaramse evidenciaram norte Conclusão Encontrouse Encontrou estudo identificação vacinal 20 2010–201 2010201 (2010–201 18212 18 12 182.1 1686 86 16.8 9,26 (9,26 10 00 −9,5% (−9,5 IC9 −13,9 139 p<0,0 p00 −11,74% 117 (−11,74 94 −9,4 p010 p<01,0 −2,08% (−2,08 −4, 0, p0194 p<0,194 194 45,7 (45,7% 32,2 (32,2% 6 (68% 26,3 (26,3% 2010–20 201020 (2010–20 1821 182. 168 16. 9,2 (9,2 −9,5 (−9, −13, p<0, p0 −11,74 (−11,7 −9, p01 p<01, −2,08 (−2,0 −4 p019 p<0,19 19 45, (45,7 32, (32,2 (68 26, (26,3 2010–2 20102 (2010–2 9, (9, (−9 −13 p<0 −11,7 (−11, −9 p<01 −2,0 (−2, − p<0,1 (45, (32, (6 (26, 2010– (2010– (9 (− −1 p< −11, (−11 −2, (−2 (45 (32 ( (26 (2010 −11 (−1 −2 (4 (3 (2 (201 (20

ABSTRACT Objective: To analyze the spatiotemporal epidemiological dynamics of meningitis in Brazil, between 2010 and 2019. Methods: Descriptive ecological study with cases and deaths due to meningitis in Brazil (2010-2019) in the National Notifiable Diseases Information System (Sistema de Informações de Agravos de Notificação – SINAN). The following analyses were performed: (I) frequency analyses of cases and deaths, prevalence rates, mortality, lethality, Fisher's exact test, and chi-square test; (II) Prais-Winstein regression; and (III) Global, Local Moran's index, and Kernel density. Results: 182,126 cases of meningitis were reported in Brazil, of which 16,866 (9.26%) resulted in death, with prevalence rates of 9.03/100,000 inhabitants, mortality of 0.84/100,000 inhabitants, and lethality of 9.26%. There was a noted trend of decreasing prevalence rates (−9.5%, 95% confidence interval — 95%CI −13.92; −4.96, p<0.01) and mortality (−11.74%, 95%CI −13.92; −9.48, p<0.01), while lethality remained stable (−2.08%, 95%CI −4.9; 0.8; p<0.1941). The majority of cases were viral meningitis (45.7%), among 1-9 years old (32.2%), while the highest proportion of deaths was due to bacterial meningitis (68%), among 40-59 years old (26.3%). In the Moran and Kernel maps of prevalence and mortality rates, municipalities in the South, Southeast, and the capital of Pernambuco in the Northeast stood out with high rates; as for lethality, the North, Northeast, and Southeast coastal areas were highlighted. Conclusion: A decrease in meningitis cases and deaths was found in this study; however, the lethality rate was higher in areas with lower prevalence, emphasizing the need to enhance actions for identifying, monitoring, and providing health care for cases, as well as expanding vaccination coverage. Objective 201 2019 Methods 20102019 (2010-2019 Sistema SINAN. SINAN . SINAN) performed I (I Fishers Fisher s test chisquare chi square II (II PraisWinstein Prais Winstein regression III (III Global Morans index density Results 182126 182 126 182,12 16866 16 866 16,86 9.26% 926 9 26 (9.26% death 903100000 03 100 000 9.03/100,00 inhabitants 084100000 0 84 0.84/100,00 −9.5%, 95 5 (−9.5% 95CI CI −13.92 1392 13 92 496 4 96 −4.96 p<0.01 p001 p 01 −11.74%, 1174 11 74 (−11.74% 948 48 −9.48 p<0.01, , −2.08%, 208 2 08 (−2.08% −4.9 49 0.8 8 p<0.1941. p01941 p<0.1941 1941 p<0.1941) 45.7%, 457 45.7% 45 7 (45.7%) 19 1 1- 32.2%, 322 32.2% 32 (32.2%) 68%, 68 68% (68%) 4059 40 59 40-5 26.3%. 263 26.3% 3 (26.3%) South North highlighted Conclusion however identifying monitoring coverage 20 2010201 (2010-201 18212 18 12 182,1 1686 86 16,8 9.26 (9.26 90310000 10 00 9.03/100,0 08410000 0.84/100,0 −9.5% (−9.5 −13.9 139 p<0.0 p00 −11.74% 117 (−11.74 94 −9.4 −2.08% (−2.08 −4. 0. p0194 p<0.194 194 45.7 (45.7% 32.2 (32.2% 6 (68% 405 40- 26.3 (26.3% 201020 (2010-20 1821 182, 168 16, 9.2 (9.2 9031000 9.03/100, 0841000 0.84/100, −9.5 (−9. −13. p<0. p0 −11.74 (−11.7 −9. −2.08 (−2.0 −4 p019 p<0.19 45. (45.7 32. (32.2 (68 26. (26.3 20102 (2010-2 9. (9. 903100 9.03/100 084100 0.84/100 (−9 −13 p<0 −11.7 (−11. −9 −2.0 (−2. − p01 p<0.1 (45. (32. (6 (26. (2010- (9 90310 9.03/10 08410 0.84/10 (− −1 p< −11. (−11 −2. (−2 (45 (32 ( (26 (2010 9031 9.03/1 0841 0.84/1 −11 (−1 −2 (4 (3 (2 (201 903 9.03/ 084 0.84/ (20 90 9.03 0.84 9.0

https://doi.org/10.1590/1980-549720240031

Immunogenicity of COVID-19 adsorbed inactivated vaccine (CoronaVac) and additional doses of mRNA BNT162b2 vaccine in immunocompromised adults compared with immunocompetent persons COVID19 COVID 19 COVID-1 CoronaVac (CoronaVac BNTb BNT b BNT162b COVID1 1 COVID-
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Ibrahim, Karim Yaqub

; Moreira, Raquel Megale

; Santos, Carolina Ferreira dos

; Strabelli, Tânia Mara Varejão

; Belizário, Juliana de Cássia

; Pinto, Maria Isabel de Moraes

; Marinho, Ana Karolina Barreto Berselli

; Pereira, Juliana Marquezi

; Mello, Liliane Saraiva de

; Ando, Mauricio Cesar

; Silva, Vitor Gabriel Lopes da

; Sato, Paula Keiko

; Lima, Marcos Alves de

; França, João Italo Dias

; Loch, Ana Paula

; Miyaji, Karina Takesaki

; Infante, Vanessa

; Precioso, Alexander Roberto

; Sartori, Ana Marli Christovam

Revista do Instituto de Medicina Tropical de São Paulo

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2024, Volume 66 elocation e24

Abstract: En | Text: En | PDF: En

ABSTRACT Inactivated COVID-19 vaccines data in immunocompromised individuals are scarce. This trial assessed the immunogenicity of two CoronaVac doses and additional BNT162b2 mRNA vaccine doses in immunocompromised (IC) and immunocompetent (H) individuals. Adults with solid organ transplant (SOT), hematopoietic stem cell transplant, cancer, inborn immunity errors or rheumatic diseases were included in the IC group. Immunocompetent adults were used as control group for comparison. Participants received two CoronaVac doses within a 28-day interval. IC received two additional BNT162b2 doses and H received a third BNT162b2 dose (booster). Blood samples were collected at baseline, 28 days after each dose, pre-booster and at the trial end. We used three serological tests to detect antibodies to SARS-CoV-2 nucleocapsid (N), trimeric spike (S), and receptor binding domain (RBD). Outcomes included seroconversion rates (SCR), geometric mean titers (GMT) and GMT ratio (GMTR). A total of 241 IC and 100 H adults participated in the study. After two CoronaVac doses, IC had lower SCR than H: anti-N, 33.3% vs 79%; anti-S, 33.8% vs 86%, and anti-RBD, 48.5% vs 85%, respectively. IC also showed lower GMT than H: anti-N, 2.3 vs 15.1; anti-S, 58.8 vs 213.2 BAU/mL; and anti-RBD, 22.4 vs 168.0 U/mL, respectively. After the 3rd and 4th BNT162b2 doses, IC had significant anti-S and anti-RBD seroconversion, but still lower than H after the 3rd dose. After boosting, GMT increased in IC, but remained lower than in the H group. CoronaVac two-dose schedule immunogenicity was lower in IC than in H. BNT162b2 heterologous booster enhanced immune response in both groups. COVID19 COVID 19 COVID-1 scarce BNTb BNT b BNT162b (IC (H SOT, SOT , (SOT) cancer comparison 28day day interval booster. . (booster) baseline 2 prebooster pre end SARSCoV2 SARSCoV SARS CoV SARS-CoV- N, N (N) S, S (S) RBD. RBD (RBD) SCR, (SCR) (GMT GMTR. GMTR (GMTR) 24 10 study antiN, antiN anti anti-N 333 33 3 33.3 79% 79 antiS, antiS 338 8 33.8 86 86% antiRBD, antiRBD RBD, 485 48 5 48.5 85 85% respectively 23 2. 15.1 151 15 1 588 58 58. 2132 213 213. BAU/mL BAUmL BAU mL 224 22 4 22. 1680 168 0 168. UmL U U/mL rd th boosting twodose groups COVID1 COVID- (SOT (booster SARS-CoV (N (S (RBD (SCR (GMTR 33. 7 48. 15. 21 16

https://doi.org/10.1590/s1678-9946202466024

10.

Hair and meanings of ethnic-racial belonging in girls' conversations ethnicracial ethnic racial girls
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Silva, Marcella de Holanda Padilha Dantas da

; Pedrosa, Maria Isabel

Estudos de Psicologia (Campinas)

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2024, Volume 41 elocation e210060

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Objective O racismo estrutural é um fenômeno sistêmico, presente na sociedade brasileira, no qual condições de subalternidade e de privilégio se distribuem entre grupos raciais, mantendo o grupo branco no poder. Sua expressão individual revela-se nas interações cotidianas. Crianças, imersas no tecido social, constituem-se na cultura e vão construindo seu pertencimento a um grupo étnico-racial. O objetivo deste estudo é identificar estereótipos sociais racializados sobre cabelos em conversas de meninas de 9-11 anos. Method Em uma escola pública foram organizados dois grupos, cada um com duas meninas negras e duas brancas. Elas participaram de sete sessões de brincadeiras, videogravadas, de 30 minutos em média. Entre os brinquedos havia: bonecas negra, loira, oriental e uma branca de cabelos castanhos. Results A análise microgenética focou segmentos de conversas sobre pertencimento étnico-racial. Conclusão Evidenciou crenças e valores racistas subjacentes aos significados sobre cabelos. sistêmico brasileira raciais poder revelase revela cotidianas Crianças social constituemse constituem étnicoracial. étnicoracial étnico racial. racial étnico-racial 911 9 11 9-1 anos brancas brincadeiras videogravadas 3 média havia negra loira castanhos 91 1 9-

Abstract Objective Structural racism is a systemic phenomenon in Brazilian society that distributes conditions of subordination and privilege among racial groups, reinforcing the dominance of the White group. Its individual expression can be seen throughout daily interactions. Children, through immersion in the social fabric, construct their cultural identity and gradually develop a sense of belonging to an ethno-racial group. The aim of this study is to identify racialized social stereotypes about hair in conversations among girls aged 9 to 11 years old. Method Two groups were organized in a public school, each consisting of two Black and two White girls. They participated in seven video-recorded play sessions, averaging 30 minutes each. Among the toys were a Black, blonde, Oriental, and a brown-haired White doll. Results Microgenetic analysis was performed, focusing on conversation segments about ethnic-racial belonging. Conclusion It revealed racist beliefs and values underlying the meanings attributed to hair. group interactions Children fabric ethnoracial ethno 1 old school videorecorded video recorded sessions 3 blonde Oriental brownhaired brown haired doll performed ethnicracial ethnic

https://doi.org/10.1590/1982-0275202441e210060

11.

Mycotoxin concentration in salt-treated wet brewers’ grains and effects of their substitution for soybean meal and corn silage salttreated salt treated brewers
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Silva, Anderson Moura da

; Hentz, Fernanda

; Dornelles, Renata da Rosa

; Martini, Maria Isabel

; Silva, Larissa Henrique da

; Ribeiro-Filho, Henrique Mendonça Nunes

Revista Brasileira de Zootecnia

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2024, Volume 53 elocation e20240013

Abstract: En | Text: En | PDF: En

ABSTRACT This study investigated the occurrence of mycotoxins in wet brewers’ grains (WBG) treated with salt (sodium chloride) and the intake, nutrient digestibility, and nitrogen use efficiency in lamb diets. Two experiments were conducted: first, WBG was distributed in plastic boxes and treated with no additive (control), sodium formate (3 g/kg of WBG), or three levels of salt—25, 30, and 35 g/kg of WBG. The WBG were stored at room temperature (17.7±4.6 ℃) for 27 days. In the second experiment, eight six-month-old male lambs were allotted to one of four total mixed ration (TMR) diets in a 4 × 4 double Latin square: 0, 10, 20, and 30% of WBG replacing corn silage and soybean meal. In the first experiment, the concentration of mycotoxins throughout the experiment was lower than the tolerance levels accepted by the European Community and Food and Drug Administration for animal feedstuffs. However, the control and sodium formate groups showed visual fungal development on the WBG surface from the sixth day and presented an unpleasant smell from day 12. In the salt treatments, fungal growth was observed on top of the WBG from day 12 and an unpleasant smell from day 15. Salt-treated WBG showed a lower pH than the control and sodium formate groups and decreased dry matter deterioration. In the second experiment, including up to 30% WBG in the TMR did not affect dry matter, organic matter, neutral detergent fiber, and acid detergent fiber intake or digestibility in lambs. However, the N digestibility and N use efficiency increased with WBG inclusion. These results suggest that salt can be used to increase the storage time of WBG up to 15 days and the inclusion of up to 30% WBG in TMR for lambs can improve N use efficiency without negatively affecting nutrient intake and digestibility. brewers (WBG chloride conducted control, , (control) 3 ( gkg g kg WBG, WBG) salt25, salt25 25, 25 salt—25 30 17.7±4.6 17746 17 7 6 (17.7±4. ℃ 2 sixmonthold six month old (TMR square 0 10 20 meal feedstuffs However treatments 1 Salttreated Salt deterioration (control salt2 salt—2 17.7±4. 1774 (17.7±4 salt— 17.7±4 177 (17.7± 17.7± (17.7 17.7 (17. 17. (17 (1

https://doi.org/10.37496/rbz5320240013

12.

Social support and suicidality during the COVID-2019 pandemic among Brazilian health care workers: longitudinal assessment of a repeated cross-sectional online survey COVID2019 COVID 2019 COVID-201 workers crosssectional cross sectional COVID201 201 COVID-20 COVID20 20 COVID-2 COVID2 2 COVID-
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Diaz, Alexandre Paim

; Pinto, Andre Braule

; Araújo, Maria Isabel Chaves

; Joaquim, Rui Mateus

; Costa, Danielle de Souza

; Serpa, Alexandre Luiz de Oliveira

; Pisani, Anthony R.

; Conwell, Yeates

; Miranda, Debora M.

; Malloy-Diniz, Leandro F.

; da Silva, Antonio G.

Brazilian Journal of Psychiatry

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2024, Volume 46 elocation e20233466

Abstract: En | Text: En | PDF: En

Objective: The risk of suicide is higher among health care workers than other workers. This study investigated the association between social support and suicidal ideation and behavior during the COVID-19 pandemic among Brazilian health care workers. Methods: This study used data from 10,885 respondents to the first (time point 1 – between May and June of 2020) and second (time point 2 – between December 2020 and February 2021) cross-sectional online surveys about mental health and quality of life among Brazilian health care workers during the COVID-19 pandemic. The relationship between social support as the independent variable (time point 1) and suicidal ideation and behavior as the outcomes (time point 2) was investigated through logistic regression analysis. Results: Greater social support was associated with a significantly lower risk of reporting suicidal ideation and behavior in the month prior to follow-up assessment (adjusted OR: 0.71, 95%CI 0.66-0.76 and adjusted OR 0.61, 95%CI 0.54-0.68, respectively). These associations were independent of sex, age, feelings of loneliness, and self-reported psychiatric disorders. Conclusion: Social support is associated with a lower risk of suicidality among health care workers, and its protective role appears more closely related to suicidal behavior. Objective COVID19 COVID 19 COVID-1 Methods 10885 10 885 10,88 time 202 2021 crosssectional cross sectional analysis Results followup follow up 071 0 71 0.71 95CI CI 95 0.660.76 066076 0.66 0.76 66 76 0.66-0.7 061 61 0.61 0.540.68, 054068 0.54 0.68, 54 68 0.54-0.68 respectively. respectively . respectively) sex age loneliness selfreported self reported disorders Conclusion COVID1 COVID- 1088 88 10,8 20 07 7 0.7 9 660 0.660.7 06607 066 0.6 076 6 0.66-0. 06 540 0.540.68 05406 054 0.5 068 0.68 5 0.54-0.6 108 8 10, 0. 0.660. 0660 0.66-0 0.540.6 0540 05 0.54-0. 0.660 0.66- 0.540. 0.54-0 0.540 0.54-

https://doi.org/10.47626/1516-4446-2023-3466

13.

Comprehensive diagnosis of advanced-stage breast cancer: exploring detection methods, molecular subtypes, and demographic influences - A cross-sectional study advancedstage advanced stage cancer methods subtypes crosssectional cross sectional
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Rivas, Fernando Wladimir Silva

; Gonçalves, Rodrigo

; Mota, Bruna Salani

; Sorpreso, Isabel Cristina Esposito

; Toporcov, Tatiana Natasha

; Filassi, José Roberto

; Lopes, Edia di Tullio

; Schio, Laura Raíssa

; Comtesse, Yann-Luc Patrick

; Baracat, Edmund Chada

; Soares Júnior, José Maria

Clinics

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2024, Volume 79 elocation 100510

Abstract: En | Text: En | PDF: En

Abstract Background Brazil faces notable Breast Cancer (BC) mortality despite lower incidence rates versus developed countries. Despite guidelines from medical societies, Brazilian public policy recommends biennial mammographic screening for women aged 50 to 69. This study investigates sociodemographic and clinical factors related to BC detection methods and clinical stage at diagnosis. Methods The authors conducted a cross-sectional study at a São Paulo tertiary hospital. Patients were divided into ‘symptomatic’ and ‘mammographic’ detection groups. Bivariate analyses by detection method and clinical stage compared groups' profiles in terms of sociodemographic and clinical characteristics. Poisson regression analyses assessed sociodemographic and molecular subtypes´ influence on “mammographic detection” prevalence and “advanced-stage BC”, reporting prevalence ratios and 95 % Confidence Intervals. Results The authors studied 1,536 BC patients admitted from January 2016 to December 2017. The “mammographic detection” group had a higher proportion of patients aged 50‒69 years (62.9 % vs. 44.1 %), white race (63.3 % vs. 51.6 %), Catholic religion (58.2 % vs. 51.1 %), and Luminal A subtype (25.2 % vs. 13.2 %) compared to the “symptomatic detection” group. Patients with early-stage disease were more likely to have higher education levels (8.1 % vs. 5.5 %) and be married (39.8 % vs. 46.6 %) compared to those with advanced-stage. Molecular subtypes were significantly associated with the detection method and stage. The prevalence of advanced-stage disease in "mammographic" (n=313) and "symptomatic" (n=1191) groups was 18.5 % and 55 %, respectively . Mammographic detection significantly reduced advanced-stage BC prevalence (PR = 0.40, 95 % CI 0.31‒0.51). Conclusion Mammographic detection reduces advanced-stage breast cancer prevalence in Brazil, emphasizing the importance of regular screenings, especially among at-risk sociodemographic groups. Enhancing mammographic screening accessibility, lowering the starting age to 40, and extending coverage to include annual mammograms can significantly lower breast cancer mortality in Brazil, benefiting public health and patient outcomes. (BC countries societies 5 69 diagnosis crosssectional cross sectional hospital ‘symptomatic symptomatic ‘mammographic characteristics advancedstage advanced BC, , BC” 9 Intervals 1536 1 536 1,53 201 2017 5069 50‒6 62.9 629 62 (62. vs 441 44 44. 63.3 633 63 3 (63. 516 51 6 51. 58.2 582 58 2 (58. 511 25.2 252 25 (25. 132 13 13. earlystage early 8.1 81 8 (8. 5. 39.8 398 39 (39. 466 46 46. advancedstage. "mammographic n=313 n313 n 313 (n=313 "symptomatic n=1191 n1191 1191 (n=1191 185 18 18. PR 040 0 40 0.40 0.31‒0.51. 031051 0.31‒0.51 31 0.31‒0.51) screenings atrisk risk accessibility outcomes 153 53 1,5 20 506 50‒ 62. (62 4 63. (63 58. (58 25. (25 8. (8 39. (39 n=31 n31 (n=31 n=119 n119 119 (n=119 04 0.4 03105 0.31‒0.5 15 1, (6 (5 (2 ( (3 n=3 n3 (n=3 n=11 n11 11 (n=11 0. 0310 0.31‒0. n= (n= n=1 n1 (n=1 031 0.31‒0 (n 03 0.31‒ 0.31 0.3

https://doi.org/10.1016/j.clinsp.2024.100510

14.

Predictors of excess fluid volume in hemodialysis patients: an observational study patients
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Fernandes, Maria Isabel da Conceição Dias

; Tinôco, Jéssica Dantas de Sá

; Fernandes, Renata Marinho

; Silva, Juliana Barbosa da

; Almeida, Anna Thays Dias

; Frazão, Cecília Maria Farias de Queiroz

; Lopes, Marcos Venícius de Oliveira

; Lira, Ana Luisa Brandão de Carvalho

Revista Brasileira de Enfermagem

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2024, Volume 77 N. 1 elocation e20220816

Abstract: Pt En Es | Text: Pt En Es | PDF: Pt | PDF: En | PDF: Es

RESUMO Objetivos: avaliar os fatores de risco para o excesso de volume de líquidos em pacientes em hemodiálise. Métodos: estudo retrospectivo caso-controle. Foram incluídos 392 pacientes (196 casos e 196 controles) de dois centros de hemodiálise. Dados sociodemográficos e 23 fatores de risco para excesso de volume de líquidos foram avaliados por meio de formulário de coleta de dados. Os dados foram analisados por meio de modelo de regressão logística multivariada. Resultados: os fatores de risco conhecimento insuficiente (OR=2,06), ingestão excessiva de líquidos (OR=2,33), retirada inadequada de líquidos durante hemodiálise (OR=2,62) e ingestão excessiva de sódio (OR=1,91) podem aumentar a chance de ocorrência de excesso de líquidos volume em pacientes em hemodiálise em aproximadamente duas vezes. Escolaridade (OR=0,95) e idade (OR=0,97) são fatores de proteção para volume excessivo de líquidos. Conclusões: conhecer esses fatores de risco pode auxiliar enfermeiros na inferência diagnóstica precisa e rápida do risco de volume excessivo de líquidos. Objetivos Métodos casocontrole. casocontrole caso controle. controle caso-controle 39 (19 19 controles 2 multivariada Resultados OR=2,06, OR206 OR OR=2,06 , 06 (OR=2,06) OR=2,33, OR233 OR=2,33 33 (OR=2,33) OR=2,62 OR262 62 (OR=2,62 OR=1,91 OR191 1 91 (OR=1,91 vezes OR=0,95 OR095 0 95 (OR=0,95 OR=0,97 OR097 97 (OR=0,97 Conclusões 3 (1 OR20 OR=2,0 (OR=2,06 OR23 OR=2,3 (OR=2,33 OR=2,6 OR26 6 (OR=2,6 OR=1,9 OR19 9 (OR=1,9 OR=0,9 OR09 (OR=0,9 ( OR2 OR=2, (OR=2,0 (OR=2,3 (OR=2, OR=1, OR1 (OR=1, OR=0, OR0 (OR=0, OR=2 (OR=2 OR=1 (OR=1 OR=0 (OR=0 OR= (OR= (OR

ABSTRACT Objectives: to assess risk factors for excess fluid volume in hemodialysis patients. Methods: a retrospective case-control study was conducted. A total of 392 patients (196 cases and 196 controls) from two hemodialysis centers were included. Sociodemographic data and 23 risk factors for excess fluid volume were assessed using a data collection form. Data were analyzed using a multivariate logistic regression model. Results: the insufficient knowledge (OR=2.06), excessive fluid intake (OR=2.33), inadequate fluid removal during hemodialysis (OR=2.62) and excessive sodium intake (OR=1.91) risk factors may increase the chance of occurrence of excess fluid volume in hemodialysis patients by approximately two times. Education level (OR=0.95) and age (OR=0.97) are protective factors for excessive fluid volume. Conclusions: knowing these risk factors may help nurses with accurate and rapid diagnostic inference of the risk of excessive fluid volume. Objectives Methods casecontrol case control conducted 39 (19 19 controls included 2 form model Results OR=2.06, OR206 OR OR=2.06 , 06 (OR=2.06) OR=2.33, OR233 OR=2.33 33 (OR=2.33) OR=2.62 OR262 62 (OR=2.62 OR=1.91 OR191 1 91 (OR=1.91 times OR=0.95 OR095 0 95 (OR=0.95 OR=0.97 OR097 97 (OR=0.97 Conclusions 3 (1 OR20 OR=2.0 (OR=2.06 OR23 OR=2.3 (OR=2.33 OR=2.6 OR26 6 (OR=2.6 OR=1.9 OR19 9 (OR=1.9 OR=0.9 OR09 (OR=0.9 ( OR2 OR=2. (OR=2.0 (OR=2.3 (OR=2. OR=1. OR1 (OR=1. OR=0. OR0 (OR=0. OR=2 (OR=2 OR=1 (OR=1 OR=0 (OR=0 OR= (OR= (OR

RESUMEN Objetivos: evaluar los factores de riesgo del exceso de volumen de líquido en pacientes en hemodiálisis. Métodos: estudio retrospectivo de casos y controles. Se incluyeron 392 pacientes (196 casos y 196 controles) de dos centros de hemodiálisis. Se evaluaron datos sociodemográficos y 23 factores de riesgo de exceso de volumen de líquido mediante un formulario de recolección de datos. Los datos se analizaron mediante un modelo de regresión logística multivariado. Resultados: factores de riesgo conocimiento insuficiente (OR=2,06), ingesta excesiva de líquidos (OR=2,33), retirada inadecuada de líquidos durante la hemodiálisis (OR=2,62) e ingesta excesiva de sodio (OR=1,91) pueden aumentar aproximadamente dos veces la posibilidad de que se produzca un exceso de volumen de líquido en pacientes en hemodiálisis. La educación (OR=0,95) y la edad (OR=0,97) son factores protectores del volumen excesivo de líquido. Conclusiones: conocer estos factores de riesgo puede ayudar a las enfermeras a realizar una inferencia diagnóstica precisa y rápida del riesgo de volumen excesivo de líquidos. Objetivos Métodos controles 39 (19 19 2 multivariado Resultados OR=2,06, OR206 OR OR=2,06 , 06 (OR=2,06) OR=2,33, OR233 OR=2,33 33 (OR=2,33) OR=2,62 OR262 62 (OR=2,62 OR=1,91 OR191 1 91 (OR=1,91 OR=0,95 OR095 0 95 (OR=0,95 OR=0,97 OR097 97 (OR=0,97 Conclusiones 3 (1 OR20 OR=2,0 (OR=2,06 OR23 OR=2,3 (OR=2,33 OR=2,6 OR26 6 (OR=2,6 OR=1,9 OR19 9 (OR=1,9 OR=0,9 OR09 (OR=0,9 ( OR2 OR=2, (OR=2,0 (OR=2,3 (OR=2, OR=1, OR1 (OR=1, OR=0, OR0 (OR=0, OR=2 (OR=2 OR=1 (OR=1 OR=0 (OR=0 OR= (OR= (OR

https://doi.org/10.1590/0034-7167-2022-0816

15.

Cultural adaptation and validity evidence of the Student Nurse Stressor-15 (SNS-15) Scale for Brazil Stressor15 Stressor 15 Stressor-1 SNS15 SNS (SNS-15 Stressor1 1 Stressor- SNS1 (SNS-1 (SNS- (SNS
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Araújo, Agostinho Antônio Cruz

; Godoy, Simone de

; Maia, Natália Maria Freitas e Silva

; Trevelin, Maria Eduarda Bonissoni

; Vedana, Kelly Graziani Giacchero

; Neufeld, Carmem Beatriz

; Freire, Neyson Pinheiro

; Ventura, Carla Aparecida Arena

; McAleer, Patricia

; Mendes, Isabel Amélia Costa

Revista Brasileira de Enfermagem

Journal Metrics
- Sobre o periódico
- SciELO Analytics

2024, Volume 77 N. 1 elocation e20230356

Abstract: Pt En Es | Text: Pt En Es | PDF: Pt | PDF: En | PDF: Es

RESUMO Objetivos: realizar a adaptação cultural e a avaliação das evidências de validade da Student Nurse Stressor-15 (SNS-15) Scale para uso no Brasil. Métodos: estudo psicométrico, conduzido a partir das etapas de tradução, síntese, retrotradução, revisão por um comitê de sete especialistas, pré-teste e avaliação das propriedades de medida com 32 e 238 estudantes de enfermagem, respectivamente. Realizou-se estatística descritiva, Análise Fatorial Exploratória (AFE), Análise Fatorial Confirmatória (AFC). Estimou-se a confiabilidade do instrumento através do Ômega de McDonald’s (ω). Resultados: a AFE subsidiou a distribuição dos quinze itens da SNS-15 em quatro fatores. Mediante AFC, alcançou-se índices satisfatórios de ajuste (Comparative Fit Index = 0,94; Tucker-Lewis Index = 0,93; Root Mean Square Error of Approximation = 0,06; Standardized Root Mean Square Residual = 0,16) e ω = 0,86. Conclusões: a versão brasileira da SNS-15 apresenta evidências que confirmam sua validade e confiabilidade. Objetivos Stressor15 Stressor 15 Stressor-1 SNS15 SNS (SNS-15 Brasil Métodos psicométrico tradução síntese retrotradução especialistas préteste pré teste 3 23 enfermagem respectivamente Realizouse Realizou se descritiva AFE, , (AFE) AFC. AFC . (AFC) Estimouse Estimou McDonalds McDonald s ω. (ω) Resultados SNS-1 fatores alcançouse alcançou Comparative 0,94 094 0 94 TuckerLewis Tucker Lewis 0,93 093 93 0,06 006 06 0,16 016 16 086 86 0,86 Conclusões Stressor1 1 Stressor- SNS1 (SNS-1 2 (AFE (AFC (ω SNS- 0,9 09 9 0,0 00 0,1 01 08 8 0,8 (SNS- 0, (SNS

ABSTRACT Objectives: to carry out the cultural adaptation and evaluation of validity evidence of the Student Nurse Stressor-15 (SNS-15) Scale for use in Brazil. Methods: psychometric study, conducted from the stages of translation, synthesis, back-translation, review by a committee of seven experts, pre-test and evaluation of measurement properties with 32 and 238 nursing students, respectively. Descriptive statistics, Exploratory Factor Analysis (EFA), and Confirmatory Factor Analysis (CFA) were performed. The reliability of the instrument was estimated using McDonald’s Omega (ω). Results: EFA subsidized the distribution of the fifteen SNS-15 items into four factors. Using AFC, satisfactory fit indices were achieved (Comparative Fit Index = 0.94; Tucker-Lewis Index = 0.93; Root Mean Square Error of Approximation = 0.06; Standardized Root Mean Square Residual = 0.16) and ω = 0.86. Conclusions: the Brazilian version of the SNS-15 presents evidence that confirms its validity and reliability. Objectives Stressor15 Stressor 15 Stressor-1 SNS15 SNS (SNS-15 Brazil Methods study translation synthesis backtranslation, backtranslation back back-translation experts pretest pre test 3 23 students respectively statistics EFA, , (EFA) CFA (CFA performed McDonalds McDonald s ω. . (ω) Results SNS-1 factors AFC Comparative 0.94 094 0 94 TuckerLewis Tucker Lewis 0.93 093 93 0.06 006 06 0.16 016 16 086 86 0.86 Conclusions Stressor1 1 Stressor- SNS1 (SNS-1 2 (EFA (ω SNS- 0.9 09 9 0.0 00 0.1 01 08 8 0.8 (SNS- 0. (SNS

RESUMEN Objetivos: realizar adaptación cultural y evaluación de evidencia de validez de la Student Nurse Stressor-15 (SNS-15) Scale para su uso en Brasil. Métodos: estudio psicométrico, realizado desde las etapas de traducción, síntesis, retrotraducción, revisión por un comité de siete expertos, pretest y evaluación de propiedades de medición con 32 y 238 estudiantes de enfermería, respectivamente. Se realizó estadística descriptiva, Análisis Factorial Exploratorio (AFE), Análisis Factorial Confirmatorio (AFC). La confiabilidad del instrumento se estimó mediante el Omega de McDonald (ω). Resultados: AFE subvencionó la distribución de los quince ítems del SNS-15 en cuatro factores. A través de la AFC se lograron índices de ajuste satisfactorios (Comparative Fit Index = 0,94; Tucker-Lewis Index = 0,93; Root Mean Square Error of Approximation = 0,06; Standardized Root Mean Square Residual = 0,16) y ω = 0,86. Conclusiones: la versión brasileña del SNS-15 presenta evidencias que confirman su validez y confiabilidad. Objetivos Stressor15 Stressor 15 Stressor-1 SNS15 SNS (SNS-15 Brasil Métodos psicométrico traducción síntesis retrotraducción expertos 3 23 enfermería respectivamente descriptiva AFE, , (AFE) AFC. . (AFC) ω. (ω) Resultados SNS-1 factores Comparative 0,94 094 0 94 TuckerLewis Tucker Lewis 0,93 093 93 0,06 006 06 0,16 016 16 086 86 0,86 Conclusiones Stressor1 1 Stressor- SNS1 (SNS-1 2 (AFE (AFC (ω SNS- 0,9 09 9 0,0 00 0,1 01 08 8 0,8 (SNS- 0, (SNS

https://doi.org/10.1590/0034-7167-2023-0356

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