ABSTRACT Planting is considered one of the most essential steps in coffee growing. Lack of uniformity in planting may compromise future operations. Therefore, verifying planting operations quality is fundamental to optimizing production processes and reducing costs. This study aimed to investigate planting techniques through Statistical Process Control (SPC) and aerial images. Carried out in two areas, managed manually and semi-mechanized in the Bom Jardim Farm (MG - Brazil). Data were collected through Remotely Piloted Aircraft (RPA). Quality control charts and density maps were used to identify variations in distribution and spacing between plants and planting rows. It was found that the planting carried out manually was 4.7% wider than projected due to spacing reduction from 0.5 m to 0.48 m. The semi-mechanized system displayed a deficit of 7% compared to the projected planting system, using 0.55 m between plants. The density map showed the most significant planting alignment variations. Despite displaying lower results than the manual system, the semi-mechanized system improvements are valid for their minimal average variations. Thus, correcting points found outside the limits can increase the efficiency of semi-mechanized planting. growing Therefore costs SPC (SPC images areas semimechanized semi mechanized MG Brazil. Brazil . Brazil) RPA. RPA (RPA) rows 47 4 7 4.7 05 0 5 0. 048 48 0.4 055 55 Thus (RPA 4. 04

ABSTRACT The development of aquaculture through the cultivation of what are considered unconventional species is an option with the potential to solve the problem of food scarcity. The aim of the present study was to evaluate the zootechnical performance of juvenile Pomacea haustrum fed different commercial diets, and subjected to different levels of salinity. After seven P. haustrum spawn had hatched in the laboratory, the juveniles were randomly selected and transferred to the rearing containers. Two different commercial diets were offered: rabbit feed with a high proportion of ingredients rich in crude vegetable protein (VP), and dog food containing balanced levels of ingredients rich in crude vegetable and animal protein (MP). The selected juveniles were randomly stocked at different salinities (0, 2 and 4 parts per thousand - ppt). The experiment lasted 65 days. Twenty-one hours after the start of the experiment, 100% of the individuals reared at a salinity of 4 ppt had died. There was a significant difference (p ≤ 0.05) between the results for zootechnical performance (average final weight, weight gain, average final growth, specific growth rate, protein efficiency and apparent feed conversion) for animals reared in fresh water or at a salinity of 2 ppt, regardless of the type of diet. The origin of the protein in the diet had no significant effect on the zootechnical performance of the individuals; however, the salinity of the water impaired development of the animals in direct proportion to its concentration. scarcity P laboratory containers offered VP, VP , (VP) MP. MP . (MP) 0, 0 (0 ppt. ppt) 6 days Twentyone Twenty one 100 died p 0.05 005 05 gain rate conversion however concentration (VP (MP ( 10 0.0 00 1 0.

RESUMO: O ensino de anatomia vem se modificando ao longo dos anos, introduzindo métodos tecnológicos, principalmente após o período pandêmico. Questiona-se o uso exclusivo da tecnologia em comparação aos métodos tradicionais de dissecação e aulas teóricas presenciais no que diz respeito à aquisição de conhecimento. Este artigo analisou a percepção de conhecimento de alunos de diversos semestres do curso de Medicina Veterinária, comparando alunos que tiveram aulas apenas online com aqueles que tiveram aulas presenciais de Anatomia Descritiva dos Animais Domésticos. Para tanto, questões foram enviadas por meio de formulário, com preenchimento voluntário e anônimo, e posteriormente analisadas estatisticamente. Os resultados indicam que 11,5% dos alunos que cursaram a disciplina remotamente falharam na aplicação dos conhecimentos em outras disciplinas, enquanto nenhum aluno do ensino presencial relatou o mesmo. A maioria dos alunos, tanto dos grupos remotos quanto dos presenciais, lembram-se do assunto, mas revisam o conteúdo com frequência. Em relação ao conhecimento teórico, o grupo online (80,8%) compreendeu melhor à medida que o curso avançava, comparado a 59,6% do grupo presencial. A ligação entre Anatomia e outras disciplinas foi mais destacada pelo grupo presencial (30,8%) em comparação ao online (15,4%). Ambos os grupos concordam que o contacto físico com peças anatômicas é essencial, mas alguns consideram possível ter um primeiro contacto com imagens ou fotografias 3D. Baseado nesse estudo preliminar, conclui-se que as interações iniciais com a área de Anatomia devem incluir técnicas pedagógicas diversificadas com comunicação empática. A utilização de recursos tecnológicos modernos é um aliado do processo de ensino-aprendizagem, e após a abstração dos conteúdos é possível o uso singular da tecnologia na manutenção e atualização do conhecimento anatômico. RESUMO anos pandêmico Questionase Questiona Veterinária Domésticos formulário anônimo estatisticamente 115 11 5 11,5 mesmo lembramse lembram assunto frequência teórico 80,8% 808 80 8 (80,8% avançava 596 59 6 59,6 30,8% 308 30 (30,8% 15,4%. 154 15,4% . 15 4 (15,4%) essencial 3D D preliminar concluise conclui empática ensinoaprendizagem, ensinoaprendizagem aprendizagem, aprendizagem ensino-aprendizagem anatômico 1 11, 80,8 (80,8 59, 30,8 3 (30,8 15,4 (15,4% 80, (80, 30, (30, 15, (15,4 (80 (30 (15, (8 (3 (15 ( (1

ABSTRACT: Anatomy teaching has been changing over the years, introducing technological methods especially after the pandemic period. An ongoing debate revolves around whether exclusive reliance on technology for anatomy classes, as opposed to traditional methods and face-to-face instruction, enhances knowledge acquisition. This study analyzed the knowledge perception of students from various semesters throughout the Veterinary Medicine course, comparing students who only had online classes with those who had face-to-face classes in Gross Anatomy of Domestic Animals. For this purpose, a questionnaire was distributed for voluntary and anonymous completion, and the responses were subsequently analyzed statistically. The results indicated that 11.5% of the students who took Anatomy remotely failed to apply the knowledge in other subjects, while no face-to-face learning student reported the same. Most students, both remote and face-to-face groups, remember the subject but review the content frequently. Regarding theoretical knowledge, the online group (80.8%) understood better as the course progressed, compared to 59.6% of the face-to-face group. The connection between Anatomy and other subjects was more highlighted by the face-to-face group (30.8%) compared to the online group (15.4%). Both groups agree that physical contact with anatomical specimens is essential; however, some believe that initial exposure through 3D images or photographs is feasible. We concluded based on this preliminary study that the initial interactions with the Anatomy field should include diversified pedagogical techniques with empathetic communication. The use of modern technological resources are allies in the teaching-learning process. Furthermore, after abstracting the contents, technology alone can effectively maintain and update anatomical knowledge. ABSTRACT years period facetoface face instruction acquisition Animals purpose completion statistically 115 11 5 11.5 same frequently 80.8% 808 80 8 (80.8% progressed 596 59 6 59.6 30.8% 308 30 (30.8% 15.4%. 154 15.4% . 15 4 (15.4%) essential however D feasible communication teachinglearning process Furthermore contents 1 11. 80.8 (80.8 59. 30.8 3 (30.8 15.4 (15.4% 80. (80. 30. (30. 15. (15.4 (80 (30 (15. (8 (3 (15 ( (1

RESUMO A busca por novas tecnologias capazes de proporcionar benefícios para uma alimentação saudável tem sido meta mundial. A presença de alimentos ricos em carotenoides pode ser fundamental para prevenir sérios problemas de saúde. Aliar alimentos com altos teores de carotenoides e acessíveis para a maior parte da população é fundamental. A alface (Lactuca sativa L.) se apresenta como uma espécie adequada para investir em pesquisas com biofortificação a partir de melhoramento genético. Assim, o objetivo com este estudo foi selecionar híbridos de alface visando à obtenção de populações com potencial agronômico e biofortificadas para carotenoides. Dez linhagens de alface cadastradas no Software “BG α Biofort” foram utilizadas nas hibridações. Os cruzamentos para obtenção dos híbridos foram planejados envolvendo duas linhagens ricas em pelo menos um dos pigmentos (clorofila e carotenoides) sendo obtidos 24 híbridos experimentais. Foram avaliados 37 genótipos (linhagens, híbridos e cultivares comercias) em delineamento em blocos casualizados quanto as variáveis agronômicas e teores de clorofila e carotenoides. Foi verificado que os híbridos 12 (UFU-189#3#4#1 × UFU MC BIOFORT 2) e 25 (UFU66#4#2 × UFU-189#3#4#1) possuem potencial para obtenção de populações de duplo propósito (produtividade e biofortificada para carotenoide). O híbrido 27 (UFU66#4#2 × UFU MC BIOFORT1) foi o que apresentou maior equilíbrio para pigmentos. Sugere-se a obtenção de populações F2 dos híbridos 12, 25 e 27 visando a obtenção de novas cultivares de alfaces biofortificadas vermelhas e verdes, para os segmentos de alface crespa, americana, mini e romana. mundial saúde Lactuca L. L genético Assim BG Biofort hibridações 2 experimentais 3 linhagens, (linhagens comercias 1 UFU189#3#4#1 UFU189341 189#3#4#1 189 4 (UFU-189#3#4# UFU66#4#2 UFU6642 UFU66 (UFU66#4# UFU-189#3#4#1 produtividade carotenoide. carotenoide . carotenoide) BIOFORT1 Sugerese Sugere F verdes crespa americana romana UFU189 UFU189#3#4# UFU18934 189341 189#3#4# 18 (UFU-189#3#4 UFU66#4# UFU664 UFU6 (UFU66#4 UFU-189#3#4# UFU18 UFU189#3#4 UFU1893 18934 189#3#4 (UFU-189#3# UFU66#4 (UFU66# UFU-189#3#4 UFU1 UFU189#3# 1893 189#3# (UFU-189#3 UFU66# (UFU66 UFU-189#3# UFU189#3 189#3 (UFU-189# (UFU6 UFU-189#3 UFU189# 189# (UFU-189 (UFU UFU-189# (UFU-18 UFU-189 (UFU-1 UFU-18 (UFU- UFU-1 UFU-

ABSTRACT The search for new technologies capable of providing benefits to healthy eating is a global goal. The consumption of foods rich in carotenoids can prevent serious health problems. Thus, the availability of foods high in carotenoids that are accessible to the majority of the population is essential. Lettuce (Lactuca sativa L.) is a suitable species for biofortification research based on genetic improvements. In this study, we aimed to select and obtain hybrid lettuce populations with high agronomic potential and biofortified carotenoid content. Ten lettuce lines registered in the “BG α Biofort” software were selected for hybridization. The crosses used to obtain the hybrids involved two strains rich in at least one of the pigments (chlorophyll and carotenoids), and 24 experimental hybrids were obtained. A total of 37 genotypes (strains, hybrids, and commercial cultivars) were evaluated using a randomized block design for agronomic variables and chlorophyll and carotenoid content. Hybrids 12 (UFU-189#3#4#1 × UFU MC BIOFORT 2) and 25 (UFU66#4#2 × UFU-189#3#4#1) had the potential to produce dual-purpose populations (yield and carotenoid biofortification). Hybrid 27 (UFU66#4#2 × UFU MC BIOFORT1) exhibited the best pigment balance. Thus, F2 hybrids 12, 25, and 27 should be obtained to produce new cultivars of biofortified red and green lettuce for curly, american, mini, and romaine lettuce segments. goal problems Thus essential Lactuca L. L improvements study content BG Biofort hybridization carotenoids, , carotenoids) 2 3 strains, (strains 1 UFU189#3#4#1 UFU189341 189#3#4#1 189 4 (UFU-189#3#4# UFU66#4#2 UFU6642 UFU66 (UFU66#4# UFU-189#3#4#1 dualpurpose dual purpose yield biofortification. . biofortification) BIOFORT1 balance F curly american mini segments UFU189 UFU189#3#4# UFU18934 189341 189#3#4# 18 (UFU-189#3#4 UFU66#4# UFU664 UFU6 (UFU66#4 UFU-189#3#4# UFU18 UFU189#3#4 UFU1893 18934 189#3#4 (UFU-189#3# UFU66#4 (UFU66# UFU-189#3#4 UFU1 UFU189#3# 1893 189#3# (UFU-189#3 UFU66# (UFU66 UFU-189#3# UFU189#3 189#3 (UFU-189# (UFU6 UFU-189#3 UFU189# 189# (UFU-189 (UFU UFU-189# (UFU-18 UFU-189 (UFU-1 UFU-18 (UFU- UFU-1 UFU-

APPLICATION OF MASS SPECTROMETRY WITH PAPER SPRAY IONIZATION AND THE OPLS-DA CHEMOMETRIC METHOD FOR THE DIAGNOSIS OF PROSTATE CANCER BY ANALYSIS OF URINE SAMPLES. In this study, paper spray ionization mass spectrometry (PSI-MS) allied to orthogonal projections on the latent structure-discrimination analysis (OPLS-DA) was employed to differentiate urine samples from patients with prostate cancer and control individuals (without prostate cancer). The parameters of sensitivity, specificity, efficiency and Matthew’s correlation coefficient determined to analyze the efficiency and quality of the OPLS-DA model obtained a value equal to 1, which means, respectively, that the model has a good performance to correctly classify true positive samples and true negatives. These results showed 100% correct classification of the samples from the training and test set, demonstrating a high efficiency of the OPLS-DA model when classifying all samples considered as belonging to the class of interest (urine from control patient) into class 1 and all samples considered as belonging to the non-interest class (urine from patients with prostate cancer) in class 0. This efficiency resulting from the application of this model suggests that the PSI-MS combined to OPLS-DA is a promisor approach for a rapid diagnosis of prostate cancer, via chemical fingerprints of urine samples. OPLSDA OPLS DA SAMPLES study PSIMS PSI MS (PSI-MS structurediscrimination structure discrimination (OPLS-DA without cancer. . sensitivity specificity Matthews Matthew s means respectively negatives 100 set patient noninterest non 0 10

RESUMO Objetivo: Descrever as características epidemiológicas de pacientes pediátricos com doença falciforme (DF) e avaliar o uso de plantas medicinais concomitantemente ao tratamento medicamentoso. Métodos: Realizou-se revisão de prontuários de pacientes pediátricos de uma instituição pública com nível de atendimento terciário; o critério de seleção foi ser criança ou adolescente com DF em acompanhamento pediátrico neste ambulatório. Nos prontuários dos pacientes selecionados foi procurado o registro do uso de plantas com finalidades medicinais. Resultados: Foram revisados 154 prontuários (100% dos pacientes ativos desse ambulatório): 99 crianças e 55 adolescentes. O genótipo predominante foi SS (58,4%), seguido do SC (29,2%). O uso de ao menos uma medicação para a DF foi relatada em 95,5% dos prontuários. Em 70,1% dos prontuários havia o relato do uso de plantas medicinais, em 276 citações, sendo 64 plantas citadas ao todo; destas, seis espécies foram citadas para o tratamento da doença de base (DF), sendo “ora-pro-nobis” (Pereskia aculeata) a principal. Das 276 citações de plantas medicinais nos prontuários, 60,5% incluíram o uso de plantas medicinais em sintomas gripais e/ou COVID-19 (tanto prevenção quanto tratamento), sendo relatadas 35 para este uso, exclusivamente ou não. Essa foi a principal finalidade de uso encontrada nos prontuários dos pacientes, seguida do uso para sintomas de dor (14,2% das citações). Conclusões: Notou-se que a maioria dos pacientes avaliados faz uso da medicina convencional, aliada à tradicional/ complementar/ alternativa, o que leva à necessidade de mais estudos nessas áreas, especialmente na pediatria, visando principalmente à segurança do paciente. Objetivo (DF medicamentoso Métodos Realizouse Realizou se terciário ambulatório Resultados 15 100% 100 (100 ambulatório) 9 5 adolescentes 58,4%, 584 58,4% , 58 4 (58,4%) 29,2%. 292 29,2% . 29 2 (29,2%) 955 95 95,5 701 70 1 70,1 27 6 todo destas DF, orapronobis ora pro nobis “ora-pro-nobis Pereskia aculeata 605 60 60,5 eou COVID19 COVID 19 COVID-1 tanto tratamento, tratamento) 3 não 14,2% 142 14 (14,2 citações. citações) Conclusões Notouse Notou convencional tradicional complementar alternativa áreas pediatria paciente 10 (10 58,4 (58,4% 29,2 (29,2% 95, 7 70, 60, COVID1 COVID- 14,2 (14, (1 58, (58,4 29, (29,2 14, (14 ( (58, (29, (58 (29 (5 (2

ABSTRACT Objective: The aim of this study was to describe the epidemiological characteristics of pediatric patients with sickle cell disease (SCD) and evaluate the use of medicinal plants in these patients concomitantly with their drug treatment. Methods: This is a review of the medical records of pediatric patients at a public institution with tertiary care. The selection criterion was to be a child or adolescent with SCD undergoing pediatric follow-up at this outpatient clinic. In the medical records of the patients selected, records of the use of plants for medicinal purposes were sought. Results: In total, 154 records (100% of total active patients followed in this clinic) were reviewed: 99 children and 55 adolescents. The predominant genotype was SS (58.4%), followed by SC (29.2%). The use of at least one medication for SCD was reported in 95.5% of the medical records. The use of medicinal plants was reported by 70.1% of patients, with 276 citations in the medical records referring to 64 different types of plants. Six plants were used for the treatment of SCD, the main one being Lemonvine/Ora-pro-nóbis (Pereskia aculeata). The use of medicinal plants was reported for flu-like symptoms and/or COVID-19 (both for prevention and treatment) by 60.5% of the citations, with 35 different plants reported for this use, exclusively or not. This use was followed by pain symptoms (14.2% of citations). Conclusions: The majority of patients in this study use both conventional and traditional/complementary/alternative medicine, highlighting the need for more studies in the area, with a special focus on patient safety. Objective (SCD Methods care followup follow up clinic selected sought Results 15 100% 100 (100 reviewed 9 5 adolescents 58.4%, 584 58.4% , 58 4 (58.4%) 29.2%. 292 29.2% . 29 2 (29.2%) 955 95 95.5 701 70 1 70.1 27 6 Lemonvine/Orapronóbis LemonvineOrapronóbis Lemonvine/Ora pro nóbis Lemonvine Ora Pereskia aculeata. aculeata aculeata) flulike flu like andor COVID19 COVID 19 COVID-1 605 60 60.5 3 not 14.2% 142 14 (14.2 citations. citations) Conclusions traditionalcomplementaryalternative traditional complementary alternative medicine area safety 10 (10 58.4 (58.4% 29.2 (29.2% 95. 7 70. Orapronóbis LemonvineOra COVID1 COVID- 60. 14.2 (14. (1 58. (58.4 29. (29.2 14. (14 ( (58. (29. (58 (29 (5 (2

Resumo Introdução: A deficiência de crescimento na doença renal crônica está relacionada à elevada morbidade e mortalidade. O retardo do crescimento nessa doença é multifatorial. É fundamental conhecer os fatores modificáveis e estabelecer estratégias para melhorar o atendimento às crianças afetadas. Objetivos: Descrever padrões de crescimento em crianças com DRC e fatores de risco associados à baixa estatura. Métodos: Analisamos retrospectivamente dados antropométricos e epidemiológicos, peso ao nascer, prematuridade e níveis de bicarbonato, hemoglobina, cálcio, fosfato, fosfatase alcalina e paratormônio de crianças com DRC estágios 3–5, não submetidas a diálise, acompanhadas por pelo menos um ano. Resultados: Incluímos 43 crianças, a maioria meninos (65%). O escore z médio de altura/comprimento/idade das crianças no início e no acompanhamento foi de –1,89 ± 1,84 e –2,4 ± 1,67, respectivamente (p = 0,011). Cinquenta e um por cento das crianças apresentaram baixa estatura, e essas crianças eram mais jovens que aquelas com estatura adequada (p = 0,027). Níveis de PTH no início do acompanhamento correlacionados com escore z de altura/comprimento/idade. Uma subanálise com crianças menores de cinco anos (n = 17) mostrou que 10 (58,8%) delas apresentaram déficit de desenvolvimento e escore z de peso/idade mais baixo (0,031) e escore z de IMC/idade mais baixo (p = 0,047). Conclusão: Crianças, especialmente mais jovens, com DRC, que não estavam em diálise, apresentaram elevada prevalência de baixa estatura. Níveis de PTH foram correlacionados com escore z de altura, e deficiência de crescimento foi associada a pior estado nutricional. Portanto, é essencial monitorar o crescimento dessas crianças, controlar o hiperparatireoidismo e fornecer suporte nutricional. Introdução mortalidade multifatorial afetadas Objetivos Métodos epidemiológicos nascer bicarbonato hemoglobina cálcio fosfato 35 3 5 3–5 diálise ano Resultados 4 65%. 65 65% . (65%) alturacomprimentoidade altura comprimento idade 189 1 89 –1,8 184 84 1,8 24 2 –2, 167 67 1,67 p 0,011. 0011 0,011 0 011 0,011) 0,027. 0027 0,027 027 0,027) n 17 58,8% 588 58 8 (58,8% pesoidade 0,031 0031 031 (0,031 IMCidade IMC 0,047. 0047 0,047 047 0,047) Conclusão Crianças nutricional Portanto 3– 6 (65% 18 –1, 1, –2 16 1,6 001 0,01 01 002 0,02 02 58,8 (58,8 0,03 003 03 (0,03 004 0,04 04 (65 –1 – 00 0,0 58, (58, (0,0 (6 0, (58 (0, ( (5 (0

Abstract Introduction: Growth failure in chronic kidney disease is related to high morbidity and mortality. Growth retardation in this disease is multifactorial. Knowing the modifiable factors and establishing strategies to improve care for affected children is paramount. Objectives: To describe growth patterns in children with chronic kidney disease and the risk factors associated with short stature. Methods: We retrospectively analyzed anthropometric and epidemiological data, birth weight, prematurity, and bicarbonate, hemoglobin, calcium, phosphate, alkaline phosphatase, and parathormone levels of children with stages 3–5 CKD not on dialysis, followed for at least one year. Results: We included 43 children, the majority of which were boys (65%). The mean height/length /age z-score of the children at the beginning and follow-up was –1.89 ± 1.84 and –2.4 ± 1.67, respectively (p = 0.011). Fifty-one percent of the children had short stature, and these children were younger than those with adequate stature (p = 0.027). PTH levels at the beginning of the follow-up correlated with height/length/age z-score. A sub-analysis with children under five (n = 17) showed that 10 (58.8%) of them failed to thrive and had a lower weight/age z-score (0.031) and lower BMI/age z-score (p = 0.047). Conclusion: Children, particularly younger ones, with chronic kidney disease who were not on dialysis had a high prevalence of short stature. PTH levels were correlated with height z-score, and growth failure was associated with worse nutritional status. Therefore, it is essential to monitor the growth of these children, control hyperparathyroidism, and provide nutritional support. Introduction mortality multifactorial paramount Objectives Methods data weight prematurity bicarbonate hemoglobin calcium phosphate phosphatase 35 3 5 3– year Results 4 65%. 65 65% . (65%) heightlength length age zscore z score followup follow up 189 1 89 –1.8 184 84 1.8 24 2 –2. 167 67 1.67 p 0.011. 0011 0.011 0 011 0.011) Fiftyone Fifty 0.027. 0027 0.027 027 0.027) heightlengthage zscore. score. subanalysis sub analysis n 17 58.8% 588 58 8 (58.8% weightage 0.031 0031 031 (0.031 BMIage BMI 0.047. 0047 0.047 047 0.047) Conclusion Children ones zscore, score, status Therefore hyperparathyroidism support 6 (65% 18 –1. 1. –2 16 1.6 001 0.01 01 002 0.02 02 58.8 (58.8 0.03 003 03 (0.03 004 0.04 04 (65 –1 – 00 0.0 58. (58. (0.0 (6 0. (58 (0. ( (5 (0

ABSTRACT Introduction: The ureteral access sheath (UAS) is a medical device that enables repeated entrance into the ureter and collecting system during retrograde intrarenal surgery (RIRS). Its impact on stone-free rates, ureteral injuries, operative time, and postoperative complications remains controversial. Therefore, we performed a systematic review and meta-analysis comparing RIRS with versus without UAS for urolithiasis management. Purpose: To compare outcomes from retrograde intrarenal surgery (RIRS) for stone extraction with or without ureteral access sheath (UAS); evaluating stone-free rate (SFR), ureteral injuries, operative time, and postoperative complications. Materials and Methods: We systematically searched PubMed, Embase, and Cochrane Library in June 2024 for randomized controlled trials (RCTs) evaluating the efficacy and safety outcomes of UAS use in RIRS for urolithiasis treatment. Articles published between 2014 and 2024 were included. Pooled risk ratios (RRs) and mean differences (MDs) were calculated for binary and continuous outcomes, respectively. Results: Five RCTs comprising 466 procedures were included. Of these, 246 (52.7%) utilized UAS. The follow-up ranged from 1 week to 1 month. UAS reduced the incidence of postoperative fever (RR 0.49; 95% confidence interval [CI] 0.29–0.84; p=0.009), and postoperative infection (RR 0.50; 95% CI 0.30–0.83; p=0.008). There were no significant differences between groups in terms of SFR (RR 1.05; 95% CI 0.99–1.11; p=0.10), ureteral injuries (RR 1.29; 95% CI 0.95–1.75; p=0.11), operative time (MD 3.56 minutes; 95% CI −4.15 to 11.27 minutes; p=0.36), or length of stay (MD 0.32 days; 95% CI −0.42 to 1.07 days; p=0.40). Conclusion: UAS leads to a lower rate of post-operative fever and infection. However, UAS did not significantly reduce or increase the SFR or the rate of ureteral injuries during RIRS for patients with urolithiasis. The use of UAS should be considered to decrease the risk of infectious complications, particularly in those who may be at higher risk for such complications. Introduction (UAS RIRS. . stonefree free rates controversial Therefore metaanalysis meta analysis management Purpose (RIRS SFR, , (SFR) Methods PubMed Embase 202 (RCTs treatment 201 included RRs (RRs MDs (MDs respectively Results 46 these 24 52.7% 527 52 7 (52.7% followup follow up month RR 0.49 049 0 49 95 [CI 0.29–0.84 029084 29 84 p=0.009, p0009 p p=0.009 009 p=0.009) 0.50 050 50 0.30–0.83 030083 30 83 p=0.008. p0008 p=0.008 008 p=0.008) 1.05 105 05 0.99–1.11 099111 99 11 p=0.10, p010 p=0.10 10 p=0.10) 1.29 129 0.95–1.75 095175 75 p=0.11, p011 p=0.11 p=0.11) MD 356 3 56 3.5 minutes 415 4 15 −4.1 1127 27 11.2 p=0.36, p036 p=0.36 36 p=0.36) 032 32 0.3 days 042 42 −0.4 107 07 1.0 p=0.40. p040 p=0.40 40 p=0.40) Conclusion post However (SFR 20 2 52.7 5 (52.7 0.4 04 9 0.29–0.8 02908 8 p000 p=0.00 00 0.5 0.30–0.8 03008 0.99–1.1 09911 p01 p=0.1 1.2 12 0.95–1.7 09517 35 3. 41 −4. 112 11. p03 p=0.3 03 0. −0. 1. p04 p=0.4 52. (52. 0.29–0. 0290 p00 p=0.0 0.30–0. 0300 0.99–1. 0991 p0 p=0. 0.95–1. 0951 −4 −0 (52 0.29–0 029 0.30–0 030 0.99–1 099 p=0 0.95–1 095 − (5 0.29– 02 0.30– 0.99– 09 p= 0.95– ( 0.29 0.30 0.99 0.95 0.2 0.9

RESUMO O armazenamento é uma etapa crucial durante a produção de grãos. Este trabalho foi realizado com o objetivo de avaliar o uso de silo bolsa como alternativa no armazenamento de grãos crioulos de feijão-caupi. Para o estudo utilizou-se amostras de feijão-caupi, das variedades Arigozinho, Manteiguinha e Quarentão, procedentes do município de Cruzeiro do Sul - Acre, safra 2021. As amostras de 500 g foram armazenadas em silos bolsa e sacos de ráfia, durante 30, 60, 90, 120 dias. O experimento foi inteiramente casualizado, com parcelas subdivididas no tempo (2 × 5), com quatro repetições. As parcelas foram as condições de armazenamento: silo bolsa e sacos de ráfia, e as subparcelas, os períodos de armazenamento: 0, 30, 60, 90 e 120 dias para cada variedade crioula de feijão-caupi. Zabrotes subfasciatus foi identificado em todas as variedades, com infestações de 49 a 98% em sacos de ráfia e inferiores a 10% em silo bolsa ao longo de 120 dias. Foi observado a depreciação na qualidade dos grãos durante o período de armazenamento em sacos de ráfia. Houve aumento na condutividade elétrica, flutuações no teor de água, redução da massa específica aparente e na germinação, devido ao maior grau de infestação em todas as variedades investigadas. Os grãos em silo bolsa apresentaram mínimas variações e mantiveram a qualidade inicial durante 120 dias. O armazenamento em silo bolsa é eficaz no controle de Z. subfasciatus e na manutenção da qualidade dos grãos das variedades Arigozinho, Manteiguinha e Quarentão por até 120 dias. feijãocaupi. feijãocaupi feijão caupi. caupi feijão-caupi utilizouse utilizou se feijãocaupi, caupi, Arigozinho Acre 2021 50 30 60 12 casualizado 2 ( 5, 5 , 5) repetições subparcelas 0 9 4 98 10 elétrica água germinação investigadas Z 202 3 6 1 20

ABSTRACT Storage is one of the main stages during grain production. The present study was conducted to evaluate the use of silo bags as an alternative for storing landrace cowpea grains. The experiment used samples of the Arigozinho, Manteiguinha, and Quarentão cowpea varieties from Cruzeiro do Sul - Acre, harvested in the 2021 crop season. The samples (500 g) were stored in raffia and silo bags for 30, 60, 90, and 120 days. The experimental design was completely randomized, arranged in a split-plot-in-time scheme (2 × 5) with four replicates. Storage conditions represented the plots: silo bags and raffia bags. The subplots comprised five storage conditions: 0, 30, 60, 90, and 120 days for each landrace cowpea variety. The insect species identified in all varieties was Zabrotes subfasciatus, with infestation ranging from 49% to 98% in raffia bags and less than 10% in silo bags over 120 days. A depreciation in grain quality was observed during storage in raffia bags. There was increase in electrical conductivity, fluctuations in water content, and reductions in bulk density and germination due to the higher degree of infestation in all the investigated varieties. The grains stored in silo bags showed minimal variations over the 120 days, maintaining their initial quality throughout the storage period. The bag silo storage system is an effective alternative for controlling Z. subfasciatus and maintaining the grain quality of the varieties Arigozinho, Manteiguinha, and Quarentão for a period of up to 120 days. production Arigozinho Manteiguinha Acre 202 season 500 (50 g 30 60 90 12 randomized splitplotintime split plot time 2 ( 5 replicates plots 0 variety 49 98 10 conductivity content Z 20 50 (5 3 6 9 1 4

Abstract Objective This study aimed to review literature from the past five years, focusing on the use of educational videos as a guidance tool for parents and guardians of children with lip and palate clefts. Source of data Conducted between April and July 2022, this integrative literature review was framed around the question: 'What is the evidence regarding the use of videos in health education for parents/guardians of children with cleft lip and palate? PICO strategy was used to develop the research. A literature search was undertaken across PubMed, Web of Science, Scopus, and the Virtual Health Library databases. Of the eight articles included in this review, four were sourced from the PubMed database, with three published in 2021. Summary of the findings The findings indicated that YouTube videos were moderately satisfactory and met the needs of parents or legal guardians to a partial extent. The majority of the videos analyzed in this review were characterized by a moderate level of informational content. One study particularly underscored that the content of these videos only partially satisfies the requirements of the parents or legal guardians of the children. Conclusions Nevertheless, such videos are considered viable alternatives for health education, offering numerous benefits yet facing challenges, primarily due to the scarcity of information on orofacial malformations. years clefts 2022 question What parentsguardians research Science Scopus databases database 2021 extent Nevertheless challenges malformations 202 20 2

Objetivos: Investigar os fatores associados à disposição para conhecer o estado sorológico para a sífilis entre estudantes do ensino superior. Métodos: Estudo transversal e analítico realizado com estudantes do ensino superior de Portugal. A coleta de dados ocorreu por meio de questionário on- line. Os dados foram analisados pela regressão logística de Poisson com variância robusta, utilizando o SPSS-24. Resultados: Incluídos 413 estudantes, maioria do sexo feminino, idade média de 20,5 anos e matriculada em cursos de saúde. Observou -se vulnerabilidades comportamentais como não uso do preservativo e uso de álcool/outras drogas; baixa percepção de risco e conhecimento ruim sobre sífilis. Menos da metade dos estudantes se dispuseram a realizar o teste para sífilis. Conclusões: A adesão ao rastreio para sífilis foi baixa e associada a fatores incomuns como menor conhecimento, baixa percepção de risco, menor idade e número de parcerias sexuais e frequentar cursos de áreas diferentes da saúde.

Objectives: To investigate the factors associated with the willingness to know the serological status for syphilis among higher education students. Methods: A cross-sectional and analytical study was conducted with higher education students in Portugal. Data collection was carried out through an online questionnaire. The data were analyzed using Poisson logistic regression with robust variance, utilizing SPSS-24. Results: A total of 413 students were included, the majority of whom were female, with an average age of 20.5 years, and enrolled in health-related courses. Behavioral vulnerabilities such as not using condoms and using alcohol/other drugs were observed; there was also a low-risk perception and poor knowledge about syphilis. Less than half of the students were willing to undergo the syphilis test. Conclusions: Adherence to syphilis screening was low and associated with uncommon factors such as lower knowledge, low risk perception, younger age, fewer sexual partnerships, and enrollment in courses outside the health field.

Objetivos: Investigar los factores asociados con la disposición a conocer el estado serológico para sífilis entre estudiantes de educación superior. Métodos: Estudio transversal y analítico realizado con estudiantes de educación superior en Portugal. La recogida de datos se realizó a través de un cuestionario en línea. Los datos se analizaron mediante regresión logística de Poisson con varianza robusta, utilizando SPSS-24. Resultados: Se incluyeron 413 estudiantes, la mayoría del sexo femenino, la edad promedio fue de 20,5 años y matriculados en carreras de salud. Observar vulnerabilidades de comportamiento como no usar condones y consumir alcohol u otras drogas; baja percepción de riesgo y escaso conocimiento sobre la sífilis. Menos de la mitad de los estudiantes estaban dispuestos a realizar la prueba de sífilis. Conclusiones: La adherencia al tamizaje de sífilis fue baja y se asoció con factores obvios como menor conocimiento, baja percepción de riesgo, menor edad y número de parejas sexuales y asistencia a cursos en áreas distintas a la salud.

ABSTRACT Introduction Chemotherapy and radiation therapy are considered standard treatments for stage II seminoma patients; however, these therapies are associated with long-term toxicities. Recently, retroperitoneal lymph node dissection has emerged as an alternative strategy, and the first three phase II trials were published in 2023 with promising results. The present study conducted a systematic review and meta-analysis to evaluate this surgery as an alternative treatment for stage IIA/B seminoma patients. Purpose Seminomas are the most common testicular tumors, often affecting young adult males. Standard treatments for stage II seminomas include chemotherapy and radiation therapy, but these therapies are associated with long-term toxicities. Thus, identifying alternative strategies is paramount. Herein, we conducted a systematic review and meta-analysis to appraise the efficacy and safety of retroperitoneal lymph node dissection (RPLND) for treating this condition. Methods We systematically searched the PubMed, Embase, and Cochrane databases for studies evaluating RPLND as a primary treatment for stage II A/B seminomas. Using a random-effects model, single proportion and means and pooled 2-year recurrence-free survival rates with hazard rates and 95% CI were calculated. Results Seven studies were included, comprising 331 males with stage II seminomas. In the pooled analysis, the recurrence rate was 17.69% (95% CI 12.31–24.75), and the 2-year RFS rate was 81% (95% CI 0.77–0.86). The complication rate was 9.16% (95% CI 6.16–13.42), the Clavien–Dindo > 2 complication rate was 8.83% (95% CI 5.76–13.31), and the retrograde ejaculation rate was 7.01% (95% CI 3.54–13.40). The median operative time was 174.68 min (95% CI 122.17–249.76 min), median blood loss was 105.91 mL (95% CI 46.89–239.22 mL), and patients with no evidence of lymph node involvement ranged from 0–16%. Conclusions Primary RPLNDs for treating stage IIA/B seminomas have favorable RFS rates, with low complication and recurrence rates. These findings provide evidence that this surgery is a viable alternative therapy for these patients. however longterm long term toxicities Recently strategy 202 results metaanalysis meta analysis IIAB IIA B tumors Thus paramount Herein (RPLND condition PubMed Embase AB A randomeffects random effects model 2year year recurrencefree free 95 calculated included 33 1769 17 69 17.69 (95 12.31–24.75, 12312475 12.31–24.75 , 12 31 24 75 12.31–24.75) 81 0.77–0.86. 077086 0.77–0.86 . 0 77 86 0.77–0.86) 916 9 16 9.16 6.16–13.42, 6161342 6.16–13.42 6 13 42 6.16–13.42) ClavienDindo Clavien Dindo 883 8 83 8.83 5.76–13.31, 5761331 5.76–13.31 5 76 5.76–13.31) 701 7 01 7.01 3.54–13.40. 3541340 3.54–13.40 3 54 40 3.54–13.40) 17468 174 68 174.6 1221724976 122 249 122.17–249.7 min, min) 10591 105 91 105.9 468923922 46 89 239 22 46.89–239.2 mL, mL) 016 0–16% 20 176 1 17.6 (9 1231247 12.31–24.7 07708 0.77–0.8 9.1 616134 6.16–13.4 4 88 8.8 576133 5.76–13.3 70 7.0 354134 3.54–13.4 1746 174. 122172497 122.17–249. 1059 10 105. 46892392 23 46.89–239. 0–16 17. ( 123124 12.31–24. 0770 0.77–0. 9. 61613 6.16–13. 8. 57613 5.76–13. 7. 35413 3.54–13. 12217249 122.17–249 4689239 46.89–239 0–1 12312 12.31–24 077 0.77–0 6161 6.16–13 5761 5.76–13 3541 3.54–13 1221724 122.17–24 468923 46.89–23 0– 1231 12.31–2 07 0.77– 616 6.16–1 576 5.76–1 354 3.54–1 122172 122.17–2 46892 46.89–2 123 12.31– 0.77 61 6.16– 57 5.76– 35 3.54– 12217 122.17– 4689 46.89– 12.31 0.7 6.16 5.76 3.54 1221 122.17 468 46.89 12.3 0. 6.1 5.7 3.5 122.1 46.8 12. 6. 5. 3. 122. 46.

Resumo Este artigo busca analisar a atuação da Controladoria Geral da União (CGU) no governo Bolsonaro, no que se refere ao incentivo à accountability social, bem como identificar as perspectivas de construção de processos democráticos com a sociedade civil a partir da nova estrutura da CGU, que está sendo alterada desde o início do governo Lula. Diante disso, são estudadas três organizações da sociedade civil que têm atuado em parceria com a CGU: o Instituto de Fiscalização e Controle (IFC), o Observatório Social do Brasil (OSB) e os Amigos Associados de Ribeirão Bonito (Amarribo). Além disso, utiliza-se metodologia qualitativa baseada em análise documental, revisão bibliográfica e entrevistas semiestruturadas realizadas com burocratas da CGU e com representantes das organizações da sociedade civil. A governança pública tem sido uma preocupação compartilhada na relação entre Estado e sociedade, em especial com a CGU se destacando na promoção do controle social. Apesar dos avanços observados, há desafios gerados por problemas estruturais, dificuldades de financiamento e desarticulação das ações em rede, o que se agravou com a pandemia de Covid-19 e o desmonte de políticas gerado pelo governo anterior. Porém, a partir de 2023, a CGU, com uma nova estrutura institucional, tem atuado no sentido de se reaproximar da sociedade civil, procurando formas e estratégias para estimular a accountability social. (CGU Bolsonaro social Lula disso IFC, IFC , (IFC) OSB (OSB Amarribo. Amarribo . (Amarribo) utilizase utiliza documental observados estruturais rede Covid19 Covid 19 Covid-1 anterior Porém 2023 institucional (IFC (Amarribo Covid1 1 Covid- 202 20 2

Abstract This paper aims to analyze the performance of Brazil’s Office Comptroller General (CGU) in the Bolsonaro Government concerning encouraging social accountability, as well as identifying the prospects for building democratic processes with civil society based on the new structure of the CGU, which has been changed since the beginning of the new Lula Government. In this sense, we also study three civil society organizations that have been working in partnership with the CGU, such as the Instituto de Fiscalização e Controle (IFC), the Observatório Social do Brasil (OSB), and the Amigos Associados de Ribeirão Bonito (Amarribo). Furthermore, we use a qualitative methodology based on document analysis, literature review, and interviews with CGU bureaucrats and representatives of civil society organizations. Despite the progress, there are challenges generated by structural problems, funding difficulties, and the disarticulation of network actions, which has been aggravated by the Covid-19 pandemic and the dismantling of policies generated by the previous government. However, since 2023, CGU, with a new institutional structure, has been working to get closer to civil society, looking for ways and strategies to stimulate social accountability. Brazils Brazil s (CGU accountability sense IFC, IFC , (IFC) OSB, OSB (OSB) Amarribo. Amarribo . (Amarribo) Furthermore analysis review progress problems difficulties actions Covid19 Covid 19 Covid-1 government However 2023 (IFC (OSB (Amarribo Covid1 1 Covid- 202 20 2

Resumo O crescimento tecnológico nas últimas décadas transformou diversas áreas da sociedade e do Estado, incluindo a defesa, devido à sua natureza tecnológica. Isso levantou discussões sobre o «espaço cibernético», o «poder cibernético» e o «domínio cibernético». O ciberespaço influencia os domínios operacionais tradicionais, tornando crucial o conhecimento do espaço cibernético, tanto próprio quanto dos adversários, como vantagem competitiva em conflitos entre Estados. Isso é conhecido como «consciência situacional», concebida por Mica Endsley nos anos 1980, definida como a capacidade de perceber, compreender e prever atividades em um espaço e tempo específicos. Esse conceito se desdobra no âmbito cibernético, criando a consciência situacional cibernética, o conhecimento das ações no espaço cibernético. Este artigo explora o papel estratégico da consciência situacional cibernética, identificando teorias e modelos de consciência situacional e seus desdobramentos na estratégia militar.

Abstract The technological growth of the last decades has changed the way many sectors of society and the state carry out their respective activities. The defense sector is part of this framework due to its essentially technological nature. With these changes, discussions began about phenomena known as ‘cyberspace’, ‘cyber power’, and ‘cyber domain’. Because cyberspace permeates and can even influence the other operational domains (sea, land, air, and space), having the right knowledge of cyberspace - both one’s own and that of one’s adversaries - has become a competitive advantage in interstate conflicts. This knowledge is called situational awareness, a concept conceived in the 1980's by Mica Endsley, then Chief Scientist of the United States Air Force, and which can be defined as the ability to perceive and understand activities in a given time and space and to predict the future evolution of the situation. This concept can be unfolded in the cyber domain, giving rise to the so-called cyber situational awareness, which generally means the full knowledge of the actions occurring in the cyber space of interest. Thus, this article aims to elucidate the strategic role of cyber situational awareness, identifying the theories and models of its emerging concept and, subsequently, its developments in military strategy.

Resumo A produção de marula na África tem uma importância social, econômica e medicinal significativa. A região semiárida de Minas Gerais, Brasil, apresenta grande potencial para o cultivo de marula, pois as condições edafoclimáticas se assemelham às de seu habitat nativo. Portanto, estudos relacionados à propagação desta espécie no semiárido são essenciais para avanços em diversas áreas relacionadas à produção de marula. As sementes de marula apresentam uma dormência ainda indefinida e os métodos para superar esta dormência não estão bem estabelecidos. Além disso, não foi estabelecido um protocolo para propagação vegetativa. Consequentemente, existem obstáculos a serem superados e viabilizar a produção comercial de mudas de marula. Constatou-se que há poucas pesquisas sobre esta cultura no Brasil, apesar do potencial para estabelecer o cultivo de marula na região semiárida do país, proporcionando mais uma opção alimentar para a população brasileira. Além das suas propriedades medicinais e do potencial de criação de emprego e geração de rendimentos em zonas áridas, o cultivo desempenha um papel na redução da pobreza e no fortalecimento da agricultura na região semiárida.

Abstract The production of marula in Africa holds significant social, economic, and medicinal importance. The semi-arid region of Minas Gerais, Brazil, has great potential for marula cultivation, as the soil and climatic conditions resemble those of its native habitat. Therefore, studies related to the propagation of this species in the semi-arid conditions are essential for advancements in various areas related to marula production. Marula seeds exhibit an as yet undefined dormancy, and methods for overcoming this dormancy have not been well-established. Additionally, a protocol for vegetative propagation has not been established. Consequently, there are obstacles to overcome and enable the commercial production of marula seedlings. Furthermore, there is limited research on this crop in Brazil, despite the potential to establish marula cultivation in the semi-arid region of the country, providing another food option for the Brazilian population. In addition to its medicinal properties and the potential for job creation and income generation in dryland areas, the cultivation play a role in poverty reduction and strengthening agriculture in the semi-arid region.