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Objective: To report on suicide plans and attempts among Brazilian physicians and to investigate the associated risk factors. Methods: From January 2018 to January 2019, a nationwide online survey was conducted among Brazilian physicians using the Tool for Assessment of Suicide Risk and the Satisfaction with Life Scale. Multivariate exploratory associations of demographic, psychological, and work-related factors were performed on reports of suicide plans and attempts. Results: Of the 4,148 participants, 1,946 (53.5%) were male, 2,527 (60.9%) were 30 to 60 years old, 2,675 (64.5%) had two to four jobs, and 1,725 (41.6%) worked 40 to 60 hours a week. The overall prevalence of suicide plans was 8.8% (n=364), and suicide attempts were reported by 3.2% (n=133) of participants. Daily emotional exhaustion (ORadj = 7.857; 95%CI 2.282-27.051, p = 0.002), weekly emotional exhaustion (ORadj = 7.953; 95%CI 2.403-26.324, p = 0.001), daily frustration at work (ORadj = 3.093; 95%CI 1.711-5.588, p < 0.001), and bisexuality (ORadj = 5.083; 95%CI 2.544-10.158, p < 0.001) were significantly associated with higher odds of suicide. Extremely dissatisfied physicians reported suicide plans and attempts in 38.3% of cases, whereas extremely satisfied physicians reported suicide plans and attempts in only 2.8% of cases (p < 0.001). Conclusion: Brazilian physicians with a history of suicide plans and attempts express emotional exhaustion and frustration at work. There is an urgent need for actions to promote professional safeguards and resilience. Objective Methods 201 2019 Scale demographic psychological workrelated related Results 4148 4 148 4,14 participants 1946 1 946 1,94 53.5% 535 53 5 (53.5% male 2527 2 527 2,52 60.9% 609 9 (60.9% 3 6 old 2675 675 2,67 64.5% 645 64 (64.5% jobs 1725 725 1,72 41.6% 416 41 (41.6% week 88 8 8.8 n=364, n364 n n=364 , 364 (n=364) 32 3.2 n=133 n133 133 (n=133 ORadj 7.857 7857 7 857 95CI CI 95 2.28227.051, 228227051 2.282 27.051, 282 27 051 2.282-27.051 0.002, 0002 0.002 0 002 0.002) 7.953 7953 953 2.40326.324, 240326324 2.403 26.324, 403 26 324 2.403-26.324 0.001, 0001 0.001 001 3.093 3093 093 1.7115.588, 17115588 1.711 5.588, 711 588 1.711-5.588 5.083 5083 083 2.54410.158, 254410158 2.544 10.158, 544 10 158 2.544-10.158 383 38 38.3 28 2.8 0.001. . Conclusion resilience 20 414 14 4,1 194 94 1,9 53.5 (53.5 252 52 2,5 60.9 (60.9 267 67 2,6 64.5 (64.5 172 72 1,7 41.6 (41.6 8. n36 n=36 36 (n=364 3. n=13 n13 13 (n=13 7.85 785 85 28227 2.28227.051 22822705 2282 2.28 27051 27.051 05 2.282-27.05 000 0.00 00 7.95 795 40326 2.40326.324 24032632 2403 2.40 26324 26.324 2.403-26.32 3.09 309 09 7115 1.7115.588 1711558 1711 1.71 5588 5.588 71 58 1.711-5.58 5.08 508 08 54410 2.54410.158 25441015 2544 2.54 10158 10.158 54 15 2.544-10.15 38. 2. 4, 19 1, 53. (53. 25 2, 60. (60. 64. (64. 17 41. (41. n3 n=3 (n=36 n=1 n1 (n=1 7.8 78 2822 2.28227.05 2282270 228 2.2 2705 27.05 2.282-27.0 0.0 7.9 79 4032 2.40326.32 2403263 240 2.4 2632 26.32 2.403-26.3 3.0 1.7115.58 171155 171 1.7 558 5.58 1.711-5.5 5.0 50 5441 2.54410.15 2544101 254 2.5 1015 10.15 2.544-10.1 (53 (60 (64 (41 n= (n=3 (n= 7. 2.28227.0 228227 22 270 27.0 2.282-27. 0. 2.40326.3 240326 24 263 26.3 2.403-26. 1.7115.5 17115 1. 55 5.5 1.711-5. 5. 2.54410.1 254410 101 10.1 2.544-10. (5 (6 (4 (n 2.28227. 22822 27. 2.282-27 2.40326. 24032 26. 2.403-26 1.7115. 1.711-5 2.54410. 25441 10. 2.544-10 ( 2.28227 2.282-2 2.40326 2.403-2 1.7115 1.711- 2.54410 2.544-1 2.2822 2.282- 2.4032 2.403- 2.5441 2.544-

https://doi.org/10.47626/1516-4446-2023-3393

Validity of the TBApp mobile application for self-care management for people with tuberculosis selfcare self care
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Assis, Lara Bezerra de Oliveira de

; Silva, Denise Maria Guerreiro Vieira da

; Silva Junior, Jucimar Maia da

; Santos, Edinilza Ribeiro dos

; Pinheiro, Jair dos Santos

; Sacramento, Daniel Souza

; Oliveira, Hermann Jacques Hernani de

; Sicsú, Amélia Nunes

Revista Brasileira de Enfermagem

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2024, Volume 77 N. 2 elocation e20230195

Abstract: Pt En Es | Text: Pt En Es | PDF: Pt | PDF: En | PDF: Es

RESUMO Objetivos: descrever o processo de validação do aplicativo móvel TBApp para a gestão do autocuidado de pessoas com tuberculose vinculadas à Atenção Primária à Saúde. Métodos: pesquisa metodológica, desenvolvida com dez juízes especialistas, realizada por meio virtual. O aplicativo foi avaliado em relação a conteúdo e qualidade da tecnologia, em sete domínios (objetividade; estrutura e aparência; relevância; funcionalidade; confiabilidade; usabilidade; e eficiência), por meio de instrumento com escala tipo Likert. Resultados: o TBApp foi considerado válido, relevante, funcional, confiável e eficaz pelos juízes especialistas. Os domínios de objetivos, estrutura e apresentação e relevância apresentaram Índice de Validade de Conteúdo global de 0,93, e os domínios de funcionalidade, confiabilidade, usabilidade e eficiência apresentaram valores de características e subcaracterísticas maiores que 0,80. Conclusões: o TBApp é uma ferramenta criativa e inovadora, podendo ser utilizado por pessoas com TB e divulgado no meio científico. Objetivos Saúde Métodos metodológica especialistas virtual tecnologia objetividade (objetividade aparência funcionalidade confiabilidade eficiência, , eficiência) Likert Resultados válido relevante funcional objetivos 093 0 93 0,93 080 80 0,80 Conclusões inovadora científico 09 9 0,9 08 8 0,8 0,

ABSTRACT Objectives: to describe the validity process of the TBApp mobile application for self-care management for people with tuberculosis linked to Primary Health Care. Methods: methodological research developed with ten expert judges, carried out virtually. The application was assessed in relation to content and technology quality in seven domains (objectivity; structure and appearance; relevance; functionality; reliability; usability; and efficiency), using an instrument with a Likert scale. Results: TBApp was considered valid, relevant, functional, reliable and effective by expert judges. The objectives, structure and presentation and relevance domains presented an overall Content Validity Index of 0.93, and the functionality, reliability, usability and efficiency domains presented characteristics and sub-characteristics values greater than 0.80. Conclusions: TBApp is a creative and innovative tool that can be used by people with TB and disseminated in the scientific community. Objectives selfcare self care Care Methods judges virtually objectivity (objectivity appearance functionality reliability efficiency, , efficiency) scale Results valid relevant functional objectives 093 0 93 0.93 subcharacteristics sub 080 80 0.80 Conclusions community 09 9 0.9 08 8 0.8 0.

RESUMEN Objetivos: describir el proceso de validación de la aplicación móvil TBApp para la gestión del autocuidado de personas con tuberculosis, vinculada a la atención primaria de salud. Métodos: investigación metodológica desarrollada con diez jueces expertos, realizada de forma virtual. La aplicación fue evaluada en relación con la calidad del contenido y la tecnología en siete dominios (objetividad; estructura y apariencia; relevancia; funcionalidad; fiabilidad; usabilidad; y eficiencia), mediante un instrumento con escala Likert. Resultados: la TBApp fue considerada válida, relevante, funcional, confiable y eficaz por los jueces expertos. Los dominios de objetivos, estructura y presentación y relevancia presentaron un Índice de Validez de Contenido general de 0,93, y los dominios de funcionalidad, confiabilidad, usabilidad y eficiencia presentaron características y subcaracterísticas valores superiores a 0,80. Conclusiones: la TBApp es una herramienta creativa e innovadora que puede ser utilizada por personas con TB y difundida en la comunidad científica. Objetivos tuberculosis salud Métodos expertos virtual objetividad (objetividad apariencia funcionalidad fiabilidad eficiencia, , eficiencia) Likert Resultados válida relevante funcional objetivos 093 0 93 0,93 confiabilidad 080 80 0,80 Conclusiones científica 09 9 0,9 08 8 0,8 0,

https://doi.org/10.1590/0034-7167-2023-0195

Decreasing inconsistent alarms notifications: a pragmatic clinical trial in a post-anesthesia care unit notifications postanesthesia post anesthesia
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Silveira, Saullo Queiroz

; Nersessian, Rafael Sousa Fava

; Abib, Arthur de Campos Vieira

; Santos, Leonardo Barbosa

; Bellicieri, Fernando Nardy

; Botelho, Karen Kato

; Lima, Helidea de Oliveira

; Queiroz, Renata Mazzoni de

; Anjos, Gabriel Silva dos

; Fernandes, Hermann dos Santos

; Mizubuti, Glenio B.

; Vieira, Joaquim Edson

; Silva, Leopoldo Muniz da

Brazilian Journal of Anesthesiology

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2024, Volume 74 N. 3 elocation 744456

Abstract: En | Text: En | PDF: En

Abstract Background: Alarms alert healthcare professionals of deviations from normal/physiologic status. However, alarm fatigue may occur when their high pitch and diversity overwhelm clinicians, possibly leading to alarms being disabled, paused, and/or ignored. We aimed to determine whether a staff educational program on customizing alarm settings of bedside monitors may decrease inconsistent alarms in the Post-Anesthesia Care Unit (PACU). Methods: This is a prospective, analytic, quantitative, pragmatic, open-label, single-arm study. The outcome was evaluated on PACU admission before (P1) and after (P2) the implementation of the educational program. The heart rate, blood pressure, and oxygen saturation alarms were selected for clinical consistency. Results: A total of 260 patients were included and 344 clinical alarms collected, with 270 (78.4%) before (P1), and 74 (21.6%) after (P2) the intervention. Among the 270 alarms in P1, 45.2% were inconsistent (i.e., false alarms), compared to 9.4% of the 74 in P2. Patients with consistent alarms occurred in 30% in the P1 and 27% in the P2 (p = 0.08). Patients with inconsistent alarms occurred in 25.4% in the P1 and in 3.8% in the P2. Ignored consistent alarms were reduced from 21.5% to 2.6% (p = 0.004) in the P2 group. The educational program was a protective factor for the inconsistent clinical alarm (OR = 0.11 [95% CI 0.04-0.3]; p < 0.001) after adjustments for age, gender, and ASA physical status. Conclusion: Customizing alarm settings on PACU admission proved to be a protective factor against inconsistent alarm notifications of multiparametric monitors. Background normalphysiologic normal physiologic status However clinicians disabled paused andor or ignored PostAnesthesia Post Anesthesia PACU. . (PACU) Methods prospective analytic quantitative pragmatic openlabel, openlabel open label, label open-label singlearm single arm study P (P1 (P2 rate pressure consistency Results 26 34 collected 27 78.4% 784 78 4 (78.4% , 7 21.6% 216 21 6 (21.6% intervention 452 45 2 45.2 i.e., ie i e (i.e. alarms, alarms) 94 9 9.4 30 0.08. 008 0.08 0 08 0.08) 254 25 25.4 38 3 8 3.8 215 5 21.5 2.6 0.004 0004 004 group OR 011 11 0.1 95% 95 [95 0.040.3 00403 0.04 0.3 04 0.04-0.3] 0.001 0001 001 age gender Conclusion (PACU (P 78.4 (78.4 21.6 (21.6 45. i.e. (i.e 9. 00 0.0 25. 3. 21. 2. 0.00 000 01 1 0. [9 040 0.040. 0040 03 0.04-0.3 78. (78. (21. i.e [ 0.040 0.04-0. (78 (21 0.04-0 (7 (2 0.04- (

https://doi.org/10.1016/j.bjane.2023.07.013

Brazilian Scarabaeoidea (Insecta: Coleoptera) in the Taxonomic Catalogue of the Brazilian Fauna, with a key for families and subfamilies Insecta (Insecta Coleoptera Fauna
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Costa-Silva, Vinícius da

; Ferreira, André da Silva

; Bordin, Bruna R.

; Basílio, Daniel S.

; Rodrigues, Diego F.

; Gama, Emanuel R.R.

; Fuhrmann, Juares

; Mariano, Júlia

; Bevilaqua, Marcus

; Cherman, Mariana A.

; Duarte, Paulo R.M.

; Grossi, Paschoal C.

; Vaz-de-Mello, Fernando Z.

Zoologia (Curitiba)

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2024, Volume 41 elocation e23075

Abstract: En | Text: En | PDF: En

ABSTRACT A comprehensive overview of Scarabaeoidea in Brazil is provided based on the Taxonomic Catalogue of the Brazilian Fauna (CTFB). Data in CTFB include 2,532 valid species within 345 genera, belonging to 21 subfamilies and 10 families. Those have been described by 272 authors from 1758 to 2023. Among these authors, Carl Hermann Conrad Burmeister (1807-1892), George Frey (1902-1976), Friedrich Ohaus (1864-1946), Julius Moser (1863-1929), and Edgar von Harold (1830-1886) stand out as the most prolific, collectively accounting for approximately 43% of all known Brazilian species of Scarabaeoidea. For taxa occurring in Brazil, we also provide a dichotomous key for use identifying Scarabaeoidea families and subfamilies, along with diagnosis, remarks, and comments on their natural history. CTFB. . (CTFB) 2532 2 532 2,53 34 genera 1 27 175 2023 18071892, 18071892 1807 1892 , (1807-1892) 19021976, 19021976 1902 1976 (1902-1976) 18641946, 18641946 1864 1946 (1864-1946) 18631929, 18631929 1863 1929 (1863-1929) 18301886 1830 1886 (1830-1886 prolific 43 diagnosis remarks history (CTFB 253 53 2,5 3 17 202 1807189 180 189 (1807-1892 1902197 190 197 (1902-1976 1864194 186 194 (1864-1946 1863192 192 (1863-1929 1830188 183 188 (1830-188 4 25 5 2, 20 180718 18 (1807-189 190219 19 (1902-197 186419 (1864-194 186319 (1863-192 183018 (1830-18 18071 (1807-18 19021 (1902-19 18641 (1864-19 18631 (1863-19 18301 (1830-1 (1807-1 (1902-1 (1864-1 (1863-1 (1830- (1807- (1902- (1864- (1863- (1830 (1807 (1902 (1864 (1863 (183 (180 (190 (186 (18 (19 (1 (

https://doi.org/10.1590/s1984-4689.v41.e23075

Caracterización de DELUX: Dispositivo de esterilización por luz ultravioleta para máscaras PFF2/N95 contra COVID-19
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Lombello, Christiane Bertachini

; Daghastanli, Nasser Ali

; Neto, Hermann Windisch

; Affonso Fonseca, Fernando Luiz

; Ambrosio, Felipe Nogueira

; Arbex, Raquel

; Fernando, Isabella Kobb

; da Silva, Victor Allisson

; dos Santos, Luisa Pataquini

; da Ana, Patricia Aparecida

Ingenius. Revista de Ciencia y Tecnología

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jun 2022, N. 27 Pages 23 - 31

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

Abstract The World Health Organization (WHO) has declared a public health pandemic state due to the transmission of the new coronavirus on March 11th, 2020. COVID-19, that is caused by SARS-CoV-2, has a very broad clinical spectrum, with predominantly respiratory symptoms developments. The role of the health professionals in fighting the pandemic requires the use of Personal Protective Equipment (PPE). PFF2 / N95 masks are suitable PPEs for this purpose. Due to the high demand for PFF2 / N95 masks to fight the pandemic, there was a shortage of this PPE worldwide. This work aims to present a characterization of the device called DELUX, utilized for UVC (ultraviolet C light spectra) sterilization of PFF2 / N95 masks, and allowing to extend the time of safe use of this PPE in emergency conditions. The photometric validation of the device resulted in the verification of the emission spectrum of the lamps used in the device, and the measurement of the optical power, demonstrating the adequacy of irradiation with UVC light, with a 15-minute cycle, and safely. Biological validation showed that DELUX is capable of inactivating SARS-CoV-2 present on the surface of PFF2 / N95 masks, thus being efficient for their sterilization. The safety offered by the sterilization cycle allows to extend the safe use of those masks.

Resumen La Organización Mundial de la Salud (OMS) declaró un estado pandémico de salud pública debido a la transmisión del nuevo coronavirus el 11 de marzo de 2020. La COVID-19, causada por el SARS-CoV-2, tiene un espectro clínico muy amplio, con predominio de desarrollos sintomáticos respiratorios. El papel de los profesionales de salud en la lucha contra la pandemia requiere un equipo de protección personal (EPP). Las máscaras PFF2 / N95 son EPP adecuados para este propósito. Debido a la gran demanda de máscaras PFF2 / N95 para combatir la pandemia, hubo escasez en el mercado. Este trabajo tiene como objetivo caracterizar un dispositivo denominado DELUX para la esterilización por UVC (espectros de luz ultravioleta C) de mascarillas PFF2 / N95, ampliando su tiempo de uso seguro en condiciones de emergencia. La validación fotométrica del dispositivo permitió la verificación del espectro de emisión de las lámparas empleadas en el dispositivo y la medición de la potencia óptica, demostrando la idoneidad de la irradiación con luz UVC, en ciclos de 15 minutos, de forma segura. La validación biológica mostró que DELUX es capaz de desactivar el SARS-CoV-2 presente en la superficie de las mascarillas PFF2 / N95, siendo así eficiente para su esterilización extendiendo el tiempo de utilización de estas mascarillas.

https://doi.org/10.17163/ings.n27.2022.03 25 downloads

Managing intrathecal administration of nusinersen in adolescents and adults with 5q-spinal muscular atrophy and previous spinal surgery
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Mendonça, Rodrigo de Holanda

; Fernandes, Hermann dos Santos

; Pinto, Rafael Barbéro Schimmelpfeng

; Matsui Júnior, Ciro

; Polido, Graziela Jorge

; Silva, André Macedo Serafim da

; Grossklauss, Luis Fernando

; Reed, Umbertina Conti

; Zanoteli, Edmar

Arquivos de Neuro-Psiquiatria

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feb 2021, Volume 79 N. 2 Pages 127 - 132

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Introdução: A atrofia muscular espinal (AME) é uma desordem neurodegenerativa dos motoneurônios inferiores frequentemente associada à ocorrência de deformidade da coluna vertebral. Nusinersena é um oligonucleotídeo antisense que aumenta os níveis da proteína SMN, sendo administrado através de injeções lombares intratecais frequentes. Assim, deformidades da coluna vertebral e abordagem cirúrgica prévia são desafios importantes para a administração de medicamentos na AME. Objetivo: descrever os métodos de imagens utilizados para administração do Nusinersena nos pacientes com AME. Métodos: Os procedimentos de administração de nusinersena em pacientes com AME dos tipos 2 e 3 submetidos à cirurgia prévia da coluna foram analisados retrospectivamente para descrever os métodos de imagem e punção, e a ocorrência de complicações. Resultados: Nove pacientes com AME (14 a 50 anos) foram submetidos a 57 punções lombares para administração de nusinersena. Seis pacientes tinham enxerto ósseo ou nenhum espaço interlaminar disponível; em cinco deles foi utilizada uma abordagem transforaminal, e outra paciente foi submetida à abertura cirúrgica de janela óssea para as injeções. A punção transforaminal foi realizada usando tomografia computadorizada (TC) em três casos e fluoroscopia nos outros dois, com taxa de sucesso semelhante. Um paciente no grupo de abordagem transforaminal apresentou radiculite pós-procedimento e outro apresentou reação vagal (hipotensão). Em três casos, com espaço interlaminar preservado, foram realizadas técnica de punção interlaminar posterior e apenas um evento adverso foi relatado (cefaleia pós-punção). Conclusão: Em pacientes com AME e cirurgia prévia, o uso de intervenção guiada por imagem é necessário para a administração de nusinersena. A técnica transforaminal é indicada nos casos onde o espaço interlaminar não está disponível, devendo ser guiada por TC ou técnicas de imagem fluoroscópica.

ABSTRACT Background: Spinal muscular atrophy (SMA) is a neurodegenerative disease of lower motor neurons associated with frequent occurrence of spinal deformity. Nusinersen is an antisense oligonucleotide that increases SMN protein level and is administrated by frequent intrathecal lumbar injections. Thus, spinal deformities and previous spinal surgery are important challenges for drug delivery in SMA. Objective: To report imaging methods used for Nusinersen injection in SMA patients. Methods: Nusinersen injection procedures in SMA types 2 and 3 patients who had previous spinal surgery were analyzed retrospectively to describe the imaging and puncture procedures, as well as the occurrence of complications. Results: Nine SMA patients (14 to 50 years old) underwent 57 lumbar punctures for nusinersen injection. Six patients had no interlaminar space available; in five of them, a transforaminal approach was used, and another one underwent a surgery to open a posterior bone window for the injections. Transforaminal puncture was performed using CT scan in three cases and fluoroscopy in the other two, with a similar success rate. One patient in the transforaminal group had post-procedure radiculitis, and another one had vagal reaction (hypotension). In three cases, with preserved interlaminar space, injections were performed by posterior interlaminar puncture, and only one adverse event was reported (post-puncture headache). Conclusion: In SMA patients with previous spinal surgery, the use of imaging-guided intervention is necessary for administering intrathecal nusinersen. Transforaminal technique is indicated in patients for whom the interlaminar space is not available, and injections should always be guided by either CT or fluoroscopy.

https://doi.org/10.1590/0004-282x-anp-2020-0200 949 downloads

Molecular characterization and phylogenetic assessment of agricultural-related noctuids (Lepidoptera: Noctuidae) of South America
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Blas, German San

; Baudino, Estela Maris

; Dias, Fernando Maia Silva

; Dolibaina, Diego Rodrigo

; Specht, Alexandre

; Casagrande, Mirna Martins

; Cornejo, Paula

; Giraudo, Walter Guillot

; Mielke, Olaf Hermann Hendrik

Revista Brasileira de Entomologia

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2021, Volume 65 N. 4 elocation e20210104

Abstract: En | Text: En | PDF: En

ABSTRACT Accurate identification of species is fundamental to every biological research. While morphological identification is a time-consuming and skilled technique, straightforward molecular techniques require the availability of a database of previously sequenced and identified specimens. For most countries of South America, species of noctuids with available sequences are scarce, mostly restricted to species of economic importance, making molecular identification untenable. Here we sequenced the mitochondrial DNA ‘barcode’ region of the cytochrome c oxidase subunit I gene of 34 specimens pertaining to 26 species of South American noctuids, 20 of these for the first time. For all species, genetic distances were higher for interspecific than for intraspecific relations, supporting the utility of DNA ‘barcodes’ to identify species. Larger intraspecific divergences occurred in species of Agrotis and Anicla, and interspecific divergences lower than 2% occurred in about one fifth of the species, all in species of Agrotis, Feltia, and Anicla. These results will allow identifying these species using DNA ‘barcodes’, either for pest management or general biological studies. Furthermore, we carried out phylogenetic analyses with those sequences and 158 other sequences of 85 species of noctuids mined from GenBank. These analyses, in every case, grouped species of the same genus suggesting that the DNA ‘barcodes’ region alone can be useful for lower level phylogeny in this group, recovering as monophyletic groups such as Copitarsia, Agrotis and Austrandesiita. Conversely, groups such as Mythimna (Mythimna) and the subgenera of Feltia were not recovered as monophyletic, suggesting the need for further taxonomic studies in these groups.

https://doi.org/10.1590/1806-9665-rbent-2021-0104

Insect (Hexapoda) diversity in the oceanic archipelago of Fernando de Noronha, Brazil: updated taxonomic checklist and new records
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Rafael, José Albertino

; Limeira-de-Oliveira, Francisco

; Hutchings, Roger William

; Miranda, Gil Felipe Gonçalves

; Silva Neto, Alberto Moreira da

; Somavilla, Alexandre

; Camargo, Alexssandro

; Asenjo, Angélico

; Pinto, Ângelo Parise

; Bello, Ayr de Moura

; Dalmorra, Camila

; Mello-Patiu, Cátia Antunes de

; Carvalho, Claudio José Barros de

; Takiya, Daniela Maeda

; Parizotto, Daniele Regina

; Marques, Dayse Willkenia Almeida

; Cavalheiro, Denis de Oliveira

; Mendes, Diego Matheus de Mello

; Zeppelini, Douglas

; Carneiro, Eduardo

; Lima, Élison Fabrício Bezerra

; Lima, Estevam Cipriano Araújo de

; Godoi, Fabio Siqueira Pitaluga de

; Pessoa, Felipe Arley Costa

; Vaz-de-Mello, Fernando Zagury

; Sosa-Duque, Francisco José

; Flores, Heloísa Fernandes

; Fernandes, Itanna Oliveira

; Silva-Júnior, José Osvaldo

; Gomes, Lucas Roberto Pereira

; Monné, Marcela Laura

; Castro, Marcelo Cutrim Moreira de

; Silva, Marcelo Peixoto Gomes da

; Couri, Márcia Souto

; Gottschalk, Marco Silva

; Soares, Matheus Mickael Mota

; Monné, Miguel Angel

; Rafael, Miriam Silva

; Casagrande, Mirna Martins

; Mielke, Olaf Hermann Hendrik

; Grossi, Paschoal Coelho

; Pinto, Paula Jéssica Costa

; Bartholomay, Pedro Reck

; Sobral, Rafael

; Heleodoro, Raphael Aquino

; Machado, Renato José Pires

; Corrêa, Robson Crepes

; Hutchings, Rosa Sá Gomes

; Ale-Rocha, Rosaly

; Santos, Sandra Duque dos

; Lima, Sheila Pereira de

; Mahlmann, Thiago

; Silva, Vera Cristina

; Fernandes, Daniell Rodrigo Rodrigues

Revista Brasileira de Entomologia

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2020, Volume 64 N. 3 elocation e20200052

Abstract: En | Text: En | PDF: En

ABSTRACT Hexapods, commonly known as insects, are a neglected taxonomic group in the Fernando de Noronha archipelago, with unanswered questions about their species richness and the ecological processes in which they are involved (e.g., colonization, introduction, establishment, and extinction). Herein, we provide an updated Hexapod checklist with current nomenclatural combinations. The entomofauna of the Fernando de Noronha archipelago is currently composed of 453 species in 21 orders. The orders, and their respective number of species, are: Blattaria (9), Coleoptera (118), Collembola (29), Dermaptera (3), Diplura (1), Diptera (134), Embioptera (1), Hemiptera (29), Hymenoptera (59), Isoptera (2), Lepidoptera (25), Mantodea (1), Neuroptera (3), Odonata (5), Orthoptera (11), Phasmatodea (1), Phthiraptera (6), Psocoptera (3), Siphonaptera (1), Thysanoptera (10), and Zygentoma (2). The archipelago has 263 new taxon records (family + genera + species). Thirty-eight species (3.39%) were described from local specimens and most of them are likely endemic species. This study more than doubles our knowledge (from the previous 190 records) of the entomofauna in this large Brazilian archipelago. This study also provides a baseline for studies on its conservation status and for implementing future environmental management programs.

https://doi.org/10.1590/1806-9665-rbent-2020-0052 2462 downloads

Probiotic Administration Increases Mandibular Bone Mineral Density on Rats Exposed to Cigarette Smoke Inhalation
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Levi, Yara Loyanne de Almeida Silva

; Picchi, Raquel Narciso

; Silva, Evelyn Kellyn Trindade

; Bremer Neto, Hermann

; Prado, Rosana Leal do

; Neves, Adrieli de Paula

; Messora, Michel Reis

; Maia, Luciana Prado

Brazilian Dental Journal

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nov 2019, Volume 30 N. 6 Pages 634 - 640

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo O tabagismo é um dos principais fatores de risco para a doença periodontal, aumentando sua prevalência e gravidade. Os probióticos surgiram como uma alternativa para a prevenção e tratamento de muitas doenças, uma vez que podem modular a resposta imune do hospedeiro e promover a modificação do microbioma. Dessa forma, o objetivo do presente estudo foi avaliar os efeitos da administração de probiótico sobre os tecidos periodontais em ratos expostos à inalação de fumaça de cigarro (CSI). Quarenta ratos foram divididos nos seguintes grupos (n=10): grupo C (controle, sem CSI e probiótico); grupo PROB (controle+probiótico); grupo CSI (CSI) e grupo CSI+PROB (CSI+probiótico). Os grupos PROB e CSI+PROB receberam 2g de uma associação de microrganismos probióticos incorporados à ração durante 6 meses. Os grupos CSI e CSI + PROB foram expostos à CSI por 60 minutos diários. Após seis meses, todos os animais foram eutanasiados e as hemi mandíbulas coletadas e processadas para análises de microtomografia computadorizada. Em relação ao peso corporal dos animais, o consumo de ração foi semelhante entre os grupos, porém, após o segundo mês os grupos C e PROB apresentaram maior ganho de peso quando comparados aos grupos CSI e CSI+PROB (p <0,05). O grupo CSI apresentou redução na densidade mineral óssea (DMO), enquanto que o grupo PROB apresentou os maiores valores (p=0,01). Pode-se concluir que a administração de probióticos promoveu aumento da DMO e, consequentemente, efeito protetor sobre as estruturas ósseas mandibulares em ratos expostos à inalação de fumaça de cigarro.

Abstract Smoking is one of the main risk factor for periodontal disease, increasing its prevalence and severity. Probiotics emerged as an alternative for the prevention and treatment of many diseases, since it can modulate the host immune response and modify the modify the microbiome. Therefore, the aim of the present study is to evaluate the effects of probiotic administration on the periodontal tissues in rats exposed to cigarette smoke inhalation (CSI). Forty rats were allocated into the following groups (n=10): group C (control, without CSI and probiotic); group PROB (control+probiotic); group CSI (CSI) and group CSI+PROB (CSI+probiotic). Groups PROB and CSI+PROB received 2g of an association of probiotic microorganisms incorporated into the feed during 6 months. Groups CSI and CSI+PROB were exposed to CSI for 60 min daily. After six months all the animals were euthanized and the hemi-mandibles were collected and processed for microcomputed tomography analyses. Regarding the body weight of the animals, feed consumption was similar among the groups, however, after the second month groups C and PROB showed higher body weight gain when compared to groups CSI and CSI+PROB (p<0.05). Group CSI presented reduced bone mineral density (BMD), whereas group PROB showed the highest values (p=0.01). It can be concluded that administration of probiotics promoted an increase in BMD and, consequently, a protective effect on the mandibular bone structures in rats exposed to inhalation of cigarette smoke.

https://doi.org/10.1590/0103-6440201802862 1208 downloads

10.

Mineral composition, histomorphometry, and bone biomechanical properties are improved with probiotic, prebiotic, and symbiotic supplementation in rats chronically exposed to passive smoking: a randomized pre-clinical study
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Tribst, Marcelo Fernandes

; Magalhães, Leticia Rocha

; Silva, Ricardo Augusto

; Caetano, Heliard Rodrigues dos Santos

; Oliveira, Weber Gutemberg Alves de

; Rufino, Marcos Natal

; Keller, Rogéria

; Sanches, Osimar de Carvalho

; Louzada, Mario Jefferson Quirino

; Bremer-Neto, Hermann

Ciência Rural

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2019, Volume 49 N. 5 elocation e20180695

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO: A fumaça de cigarro em grandes centros é uma das causas mais importantes de doenças inflamatórias crônicas em saúde pública e esta associada à diminuição de massa óssea, processo de consolidação e remodelação óssea. Os alimentos funcionais suplementados na dieta, devido sua capacidade de melhorar a absorção intestinal e competir com microrganismos patógenos, podem contribuir para a melhora da qualidade óssea. Portanto, o objetivo desse estudo foi avaliar os efeitos da suplementação de alimentos funcionais, probiótico, prebiótico ou simbiótico, na composição mineral, histomorfometria e nas propriedades biomecânicas ósseas de ratos em fase de crescimento expostos cronicamente a fumaça do cigarro (T). Sessenta e quatro ratos machos jovens foram randomicamente distribuídos em oito grupos (n=8): controle (C) [dieta basal (DB)]; probiótico (Pro) [DB + probiótico (Lactobacillus acidophilus, Enterecoccusfaecium, Bifidobacterium thermophilumandBifidobacterium longum (2-5 109 UFC cada)]; prebiótico (Pre) [DB + prebiótico (mananoligossacarídeo)]; simbiótico (Sym) (DB + probiótico + prebiótico); controle fumante (CS) [(DB + protocolo de exposição ao tabagismo passivo(PT)]; probiótico fumante (ProS) (DB + probiótico + PT); prebiótico fumante (PreS) (DB + prebiótico + PT); e simbiótico fumante (SymS) (DB + prebiótico + probiótico + PT). Os animais foram mortos após 189 dias de período experimental.Os resultados revelaram que a suplementação com probióticos, prebióticos e simbióticos melhoraram significativamente (P<0,05) os parâmetros: P, Ca, Mg, DMO, CMO, resistência, resiliência e tamanho da área das diáfises dos fêmures dos animais expostos, cronicamente ou não, a fumaça do cigarro. Os resultados permitem concluir que a suplementação dos alimentos funcionais melhorou a saúde óssea de ratos expostos cronicamente ou não a fumaça do cigarro.

ABSTRACT: Cigarette smoke in large centers is one of the most important causes of chronic inflammatory diseases in public health and is associated with a decrease in bone mass, consolidation process, and bone remodeling. Due to their ability to improve intestinal absorption and compete with pathogenic microorganisms, dietary supplementation with functional foods may contribute to improvement in bone quality. Therefore, the objective of this study was to evaluate the effects of functional, probiotic, prebiotic, or symbiotic food supplementation on mineral composition, histomorphometry, and bone biomechanical properties of rats in the growth phase, chronically exposed to cigarette smoke (T).Sixty-four young male rats were randomly assigned to eight groups (n=8): control (C) [standard diet (SD)]; probiotic (Pro) [SD + probiotic (Lactobacillus acidophilus, Enterococcus faecium, Bifidobacterium thermophilum and Bifidobacterium longum) (2-5 109 UFC each)]; prebiotic (Pre) [SD+ prebiotic (mannan oligosaccharide)]; symbiotic (Sym) (SD + probiotic + prebiotic); control smoking (SC) [(SD + exposure protocol to passive smoking (PS)]; probiotic smoking (ProS) (SD + probiotic + PS); prebiotic smoking (PreS) (SD + prebiotic + PS), and symbiotic smoking (SymS)(SD + prebiotic + probiotic + PS). The animals were euthanized after 189 days of the experimental protocol. Results showed that supplementation with probiotics, prebiotics, and symbiotics significantly improved (P<0.05) the parameters: P, Ca, Mg, BMD, BMC, strength, resilience, and size of area of the femoral diaphysis of the animals chronically exposed or not cigarette smoke. We concluded that functional food supplementation improved the bone health of rats chronically exposed or not to cigarette smoke.

https://doi.org/10.1590/0103-8478cr20180695 1533 downloads

11.

Knowledge management for the sustainable development of the semi-arid region in Northeastern Brazil
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Brito, Lydia Maria Pinto

; Silva, Naeldson Expedito Alves da

; Castro, Ahiram Brunni Cartaxo de

; Nodari, Cristine Hermann

; Silva, Arthur William Pereira da

Ciência Rural

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2019, Volume 49 N. 4 elocation e20180762

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO: O objetivo deste estudo foi analisar a percepção da gestão do conhecimento em gestores de uma universidade pública na Região Semiárida do Nordeste brasileiro, especialmente seus processos táticos e estratégicos para produzir conhecimento sobre esta Região. A análise foi conduzida segundo a perspectiva de administradores nesta universidade tendo em vista o desenvolvimento sustentável da região. Este foi um estudo qualitativo. Todos os dados foram coletados por meio de entrevistas estruturadas, usando um questionário baseado no Diagnóstico de Gestão do Conhecimento como modelo estruturante. Os resultados mostraram que a Gestão do Conhecimento é uma prática que está amadurecendo. Entretanto, a gestão do conhecimento está viabilizando mudanças institucionais e gerando capacidade da organização para implementar soluções e promover o desenvolvimento sustentável da região semiárida no Nordeste do Brasil.

ABSTRACT: The objective of this study was to analyze the knowledge management perception in managers of a public university in the Brazilian Northeastern Semiarid Region, especially their tactical and strategic processes to produce knowledge about this region. The analysis was conducted according to the perspective of administrators at this university with a view to the sustainable development of the region. This was a qualitative descriptive study. All data were collected through structured interviews, using a questionnaire based on the Knowledge Management Diagnosis as a structuring model. Results showed that Knowledge Management is still a maturing practice. However, knowledge management is making institutional changes feasible and generating organization capacity to implement solutions and promote the sustainable development of the semi-arid region in the Northeastern Brazil.

https://doi.org/10.1590/0103-8478cr20180762 1391 downloads

12.

Falsa percepção de gratuidade: a prática do zero-rating e o Marco Civil da Internet
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GARCIA E SILVA, Hermann Bergmann

; MARQUES, Rodrigo Moreno

Transinformação

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2019, Volume 31 elocation e180021

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Diante das recentes iniciativas para eliminação, nos Estados Unidos, das regras de tratamento não discriminatório do fluxo de informações e conteúdos na Web, surgem novos desafios para a governança da Internet, notadamente no que se refere à regulação de práticas que restringem o acesso informacional dos usuários. No contexto brasileiro, o Marco Civil da Internet estabeleceu a neutralidade de rede como um princípio norteador para o uso da Internet no país, ou seja, instituiu a obrigação de tratamento isonômico dos pacotes de dados que carregam o conteúdo que circula na Internet. Nesse cenário, a presente investigação tem como objetivo confrontar a oferta de gratuidade no tráfego de dados associados a determinadas aplicações ou conteúdos, prática denominada de zero-rating, com o princípio da neutralidade de rede. Para tanto, foi desenvolvida uma pesquisa descritiva de natureza qualitativa, fundamentada em análises bibliográfica e documental. Os resultados apontam que o zero-rating não é compatível com as disposições normativas estabelecidas no marco regulatório para a Internet no Brasil. Em síntese, a pesquisa problematiza e questiona as práticas que limitam a circulação de conteúdos e inibem a liberdade de escolha dos usuários na rede mundial, confrontando-as com a governança da Internet no Brasil.

Abstract In the face of recent initiatives to eliminate, in the United States, the non-discriminatory rules for the flow of information and contents through the web, new regulatory challenges arise for the governance of Internet, especially in regard to the regulation of practices that restrict the informational access of Internet users. In the Brazilian context, the Civil Rights Framework for the Internet established net neutrality as a guiding principle for Internet use in the country, that is, it instituted the obligation of isonomic treatment of data packets that carry content through the Internet. In this scenario, the present paper aims to confront the offering of Internet bundles that are free of charge for certain applications or contents, practice known as zero-rating, with the net neutrality principle. Therefore, a descriptive research of qualitative nature was developed, based on bibliographic and documentary analyses. The results indicate that zero-rating is not compatible with the normative provisions established in the regulatory framework for the Internet in Brazil. In summary, the research problematizes and questions the practices that limit the flow of web content and prevent users` freedom of choice on the world wide web and confronts them with the Internet governance in Brazil.

https://doi.org/10.1590/2318-0889201931e180021 2232 downloads

13.

Muscle Strength Training is Better than the Use of Growth Hormone (GH) in Bone Health of Wistar Rats
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Caetano, Heliard Rodrigues dos Santos

; Castoldi, Robson Chacon

; Zanuto, Éverton Alex Carvalho

; Ozaki, Guilherme Akio Tamura

; Garcia, Thiago Alves

; Pereira, João Domingos Augusto dos Santos

; Constantino, Carlos José Leopoldo

; Bremer-Neto, Hermann

; Giometti, Ines Cristina

; Camargo, Regina Celi Trindade

; Camargo-Filho, José Carlos Silva

; Belangero, William Dias

International Journal of Morphology

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2019, Volume 37 N. 1 Pages 104 - 110

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

SUMMARY: The objective of this study was to evaluate the effects of growth hormone (GH) and muscle strength training (ST) on the composition of bone tissue of Wistar rats through Raman spectroscopy. In total, 40 male rats were randomly distributed into four groups: (N = 10) control (C), control with the application of GH (GHC), strength training (T), and strength training with the application of GH (GHT). The training consisted of four series of 10 water jumps, performed three times a week, with an overload corresponding to 50 % of body weight and duration of four weeks. GH was applied at a dose of 0.2 IU / kg in each animal three times a week and every other day. After four weeks, the animals were euthanized and the right femurs collected for analysis of the bone structure. Raman spectroscopy (ER) was used to observe the following compounds from their respective bands: Calcium Carbonate-Triglycerides (fatty acids) 1073 cm-1, Collagen type I 509 cm-1, Bone-DNA Phosphate (Protein) 589 cm-1, Phosphate Phospholipids 1078 cm-1. For the statistical analysis, the Shapiro-Wilk and ANOVA One-Way variance analysis normality tests were performed, followed by the Tukey post-test. The results showed an increase in the concentrations of calcium carbonate-triglycerides (fatty acids), type I collagen, bone phosphate-DNA (protein), and phosphate phospholipids in all experimental groups, with or without ST and/or GH , But only the isolated training group differed significantly from the control group (P <0.05). It was concluded that all treatments could promote bone tissue gain, however, only the T group demonstrated a significant difference in the mineral compounds analyzed.

RESUMEN: El objetivo del estudio fue avaluar el efecto de la aplicación de la hormona del crecimiento (GH) y entrenamiento de la fuerza muscular (EF) en la composición del tejido óseo de ratas Wistar a partir de la espectroscopía Raman. Fueron utilizadas 40 ratas machos distribuidas de forma aleatoria en cuatro grupos (n=10): control (C), control y aplicación de GH (GHC), entrenamiento de la fuerza muscular (EF) y entrenamiento de la fuerza muscular y aplicación del GH (GHE). El entrenamiento fue consistió en cuatro series de 10 saltos acuáticos, realizados tres veces en la semana, con sobrecarga correspondiente a 50 % de la masa corporal y durante cuatro semanas. El GH fue aplicado en la dosificación de 0,2 UI/kg en cada animal, tres veces en la semana y en días alternados. Después de cuatro semanas, los animales fueran eutanasiados y retirados los fémures derechos para un análisis de la estructura ósea. La espectroscopía Raman fue utilizada para observar los siguientes compuestos a partir de las respectivas bandas: Carbonato de Calcio-Triglicéridos (ácidos grasos) 1073 cm-1, Colágeno Tipo I 509 cm-1, Fosfato Óseo-DNA (Proteína) 589 cm1, Fosfato Fosfolípidos 1078 cm-1. Para el análisis estadístico, fueron realizadas las pruebas Shapiro-Wilk y el análisis de variancia ANOVA One-Way, seguida de test post hoc de Tukey. Los resultados revelaran aumento de la concentración de Carbonato de Calcio-Triglicéridos (ácidos grasos), Colágeno Tipo I, Fosfato Óseo- DNA (Proteína), Fosfato Fosfolípidos en todos los grupos experimentales, asociados o no a la realización del EF y/o aplicación del GH. Además, solamente el grupo EF mostró diferencia significativa del grupo C (p<0,05). Es posible concluir que todos los tratamientos mostraran aumentos en el tejido óseo, sin embargo, solamente el grupo T demostró una diferencia significativa en los compuestos minerales analizados.

670 downloads

14.

Immature stages of Temenis laothoe meridionalis Ebert (Lepidoptera, Nymphalidae, Biblidinae)
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Salik, Lucy Mila Garcia

; Dias, Fernando Maia Silva

; Carneiro, Eduardo

; Casagrande, Mirna Martins

; Mielke, Olaf Hermann Hendrik

Revista Brasileira de Entomologia

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jan 2017, Volume 61 N. 1 Pages 16 - 24

Abstract: En | Text: En | PDF: En

ABSTRACT The external morphology and life cycle of the immature stages of Temenis laothoe meridionalis Hübner, [1819] (Lepidoptera, Nymphalidae, Biblidinae), associated with Serjania laruotteana (Sapindaceae) in Curitiba, Paraná, Brazil, are described and illustrated with photographs and images from scanning electron microscopy. Special aspects of the external morphology are compared to the immature stages of other species of Biblidinae.

https://doi.org/10.1016/j.rbe.2016.10.002 1047 downloads

15.

Probiotic therapy reduces inflammation and improves intestinal morphology in rats with induced oral mucositis
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GERHARD, Dayana

; SOUSA, Frederico José da Silva Simão de

; ANDRAUS, Rodrigo Antonio Carvalho

; PARDO, Paulo Eduardo

; NAI, Gisele Alborguetti

; NETO, Hermann Bremer

; MESSORA, Michel Reis

; MAIA, Luciana Prado

Brazilian Oral Research

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2017, Volume 31 elocation e71

Abstract: En | Text: En | PDF: En

Abstract The aim of the present study was to evaluate the effect of systemic administration of probiotics (PROB) on the progression of experimentally induced oral and intestinal mucositis in rats immunosuppressed by chemotherapy (5-fluorouracil: 5-FU). Twenty-four rats were divided into the following groups (n=6): GC (control), GPROB, G5FU and G5-FU/PROB. Groups GPROB and G5-FU/PROB received 1 g of probiotic incorporated into each 100 g of feed (Bacillus subtilis, Bifidobacterium bifidum, Enterococcus faecium and Lactobacilllus acidophilus), beginning 30 days before oral mucositis induction. Groups G5FU and G5-FU/PROB received 60 mg/kg of 5-FU on days 0 and 2. The left oral mucosa of each animal was irritated by mechanical trauma (days 1 and 2). On days 3 and 7, three animals from each group were sacrificed, and their oral mucosa and small intestine were biopsied and processed for histopathological analysis. Groups G5-FU and G5-FU/PROB showed ulcerated oral lesions at day 3, with progression in group G5-FU and regression in group G5-FU/PROB at day 7. Histologically, less severe signs of inflammation in the oral mucosa were observed in group G5-FU/PROB than in group G5-FU. Regarding the intestine, villus-related defects of lesser magnitude were observed in group G5-FU/PROB, compared with group G5-FU. Group GPROB showed greater villus height than group GC. It can be concluded that probiotic supplementation reduced oral and intestinal inflammation in immunosuppressed rats with experimentally induced mucositis, and may protect the intestine from changes induced by chemotherapy, thus contributing to overall health.

https://doi.org/10.1590/1807-3107bor-2017.vol31.0071 2919 downloads

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