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ABSTRACT Objective: To assess dentists' knowledge from Minas Gerais, Brazil, about dentoalveolar trauma (DT) and their experiences during the COVID-19 pandemic. Material and Methods: An online questionnaire with 34 questions was applied to collect personal data, professional training, self-assessment of experience/knowledge about DT, experience in care provided during the social distancing, and knowledge/conduct. The specific responses were evaluated based on the guidelines of the International Association of Dental Traumatology (IADT). Descriptive analysis and Pearson's chi-square test were performed. The level of significance was set at p≤0.05. Results: Most professionals (97.7%) had received information on DT, and only 4.6% of the participants considered their knowledge poor or very poor. However, 92.7% felt the need for more information on the subject. Regarding experiences during the pandemic, 55.7% provided trauma care during that period. Forty percent of the consultations were performed in person, and 33.3% of the professionals noted an increase in cases during the pandemic; 56.6% reported that the frequency did not change. The overall mean number of correct answers about DT was 5.29±2.11, indicating an acceptable level of knowledge. The mean percentage of hits for the specific questions was 44.1%. Conclusion: Although the level of knowledge of the dentists evaluated was acceptable, some aspects were deficient, with the need for more information about the IADT guidelines. Objective Gerais Brazil (DT COVID19 COVID 19 COVID-1 pandemic Methods 3 data training selfassessment self assessment experienceknowledge distancing knowledgeconduct conduct knowledge/conduct IADT. . (IADT) Pearsons Pearson s chisquare chi square p005 p 0 05 p≤0.05 Results 97.7% 977 97 7 (97.7% 46 4 6 4.6 However 927 92 92.7 subject 557 55 55.7 period person 333 33 33.3 566 56 56.6 change 529211 5 29 2 11 5.29±2.11 441 44 1 44.1% Conclusion deficient COVID1 COVID- (IADT p00 p≤0.0 97.7 9 (97.7 4. 92. 55. 33. 56. 52921 5.29±2.1 44.1 p0 p≤0. 97. (97. 5292 5.29±2. 44. p≤0 (97 529 5.29±2 p≤ (9 52 5.29± ( 5.29 5.2 5.

https://doi.org/10.1590/pboci.2024.013

Phytotoxicity of mixtures of phytosanitary products recommended for use in maize
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Silva, Gabriela de Souza da

; Oliveira Junior, Francisco Freire de

; Carneiro, Rúbia de Moura

; Souza, Fernando Ramos de

; Ferreira, Luana Jessica da Silva

; Simões, Jonathan Almeida Santos

; Machado, Aroldo Ferreira Lopes

; Pinho, Camila Ferreira de

Revista Ciência Agronômica

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2024, Volume 55 elocation e20238715

Abstract: En | Text: En | PDF: En

ABSTRACT The use of tank mixtures has long been a practice in the phytosanitary management of agricultural crops. However, when different molecules are mixed in a tank, interactions may occur that reduce the efficiency of the products and cause a loss of selectivity in the crops. The aim of this study was to evaluate selectivity in maize, with a tank mixture of different phytosanitary products recommended for use with the crop. The following products were used: herbicides - Sanson®, Soberan®, Callisto®, Zapp Pro®; fungicides - Priori Xtra®, Nativo®, Tebufort®, Aproach Prima®; insecticides - Connect®, Lorsban® 480 BR, Karate Zeon®; and nutrition - Kellus Manganese®, Kellus Blindex®. The experimental units consisted of 5-litre pots, containing two plants per pot, with the products applied at phenological stage V6. Assessments were made of phytotoxicity, transient chlorophyll a fluorescence, chlorophyll content and shoot dry weight. The data obtained in the experiment were submitted to ANOVA (p ≤ 0.05), and when significant, to the Scott-Knott test (p ≤ 0.05). The maize crop suffered phytotoxicity of up to 30%, with the plants recovering from 28 DAA. The phytotoxicity was caused by mixing the different products in the spraying solution, mainly due to the synergism caused by the mixture of the herbicides nicosulfuron and tembotrione with the insecticide chlorpyrifos and the fertiliser Kellus Manganese®, which aggravated the incompatibility of some treatments. The results of this study defined which phytosanitary products recommended for use with maize should not be mixed in the same spraying solution due to the possibility of damaging the crop. crops However used Sanson Sanson® Soberan Soberan® Callisto Callisto® Pro® Pro Xtra Xtra® Nativo Nativo® Tebufort Tebufort® Prima® Prima Connect Connect® Lorsban 48 BR Zeon® Zeon Manganese Manganese® Blindex Blindex® 5litre litre 5 pots pot V6 V fluorescence weight p 0.05, 005 0.05 , 0 05 0.05) significant ScottKnott Scott Knott 0.05. . 30 30% 2 DAA treatments 4 00 0.0 3 0.

https://doi.org/10.5935/1806-6690.20240045

Brazilian consensus recommendations on the diagnosis and treatment of autoimmune encephalitis in the adult and pediatric populations
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Dutra, Lívia Almeida

; Silva, Pedro Victor de Castro

; Ferreira, João Henrique Fregadolli

; Marques, Alexandre Coelho

; Toso, Fabio Fieni

; Vasconcelos, Claudia Cristina Ferreira

; Brum, Doralina Guimarães

; Pereira, Samira Luisa dos Apóstolos

; Adoni, Tarso

; Rocha, Leticia Januzi de Almeida

; Sampaio, Leticia Pereira de Brito

; Sousa, Nise Alessandra de Carvalho

; Paolilo, Renata Barbosa

; Pizzol, Angélica Dal

; Costa, Bruna Klein da

; Disserol, Caio César Diniz

; Pupe, Camila

; Valle, Daniel Almeida do

; Diniz, Denise Sisterolli

; Abrantes, Fabiano Ferreira de

; Schmidt, Felipe da Rocha

; Cendes, Fernando

; Oliveira, Francisco Tomaz Meneses de

; Martins, Gabriela Joca

; Silva, Guilherme Diogo

; Lin, Katia

; Pinto, Lécio Figueira

; Santos, Mara Lúcia Schimtz Ferreira

; Gonçalves, Marcus Vinícius Magno

; Krueger, Mariana Braatz

; Haziot, Michel Elyas Jung

; Barsottini, Orlando Graziani Povoas

; Nascimento, Osvaldo José Moreira do

; Nóbrega, Paulo Ribeiro

; Proveti, Priscilla Mara

; Castilhos, Raphael Machado do

; Daccach, Vanessa

; Glehn, Felipe von

Arquivos de Neuro-Psiquiatria

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2024, Volume 82 N. 7 elocation s00441788586

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Antecedentes Encefalites autoimunes (EAIs) são um grupo de doenças inflamatórias caracterizadas pela presença de anticorpos contra antígenos neuronais e gliais, que ocasionam sintomas psiquiátricos subagudos, queixas de memória e distúrbios anormais do movimento. A maioria dos pacientes é jovem, e o atraso no tratamento está associado a pior prognóstico. Objetivo Com o apoio da Academia Brasileira de Neurologia (ABN) e da Sociedade Brasileira de Neurologia Infantil (SBNI), desenvolvemos um consenso sobre o diagnóstico e o tratamento da EAIs no Brasil utilizando a metodologia Delphi. Métodos Um total de 25 especialistas, incluindo neurologistas e neurologistas infantis, foram convidados a participar. Resultados Os especialistas concordaram que os pacientes com critérios de possíveis EAIs devem ser submetidos ao rastreio de anticorpos antineuronais no soro e no líquido cefalorraquidiano (LCR) por meio das técnicas de ensaio baseado em tecidos (tissue-based assay, TBA, em inglês) e ensaio baseado em células (cell-based assay, CBA, em inglês). As crianças também devem ser submetidas ao rastreio de de anticorpo contra a glicoproteína da mielina de oligodendrócitos (anti-myelin oligodendrocyte glycoprotein, anti-MOG, em inglês). O tratamento deve ser iniciado dentro das primeiras 4 semanas dos sintomas, sendo as opções de primeira linha metilprednisolona combinada com imunoglobulina intravenosa (IGIV) ou plasmaférese. O tratamento de segunda linha inclui rituximabe e ciclofosfamida. Bortezomib e tocilizumab são opções de tratamento de terceira linha. A maioria das crises epilépticas nas EAIs são sintomáticas, e os fármacos anticrise podem ser desmamadas após a fase aguda. Em relação à encefalite antirreceptor de N-metil-D-aspartato (anti-N-methyl-D-aspartate receptor, anti-NMDAR, em inglês), os especialistas concordaram que agentes imunossupressores orais não devem ser usados. Os pacientes devem ser avaliados na fase aguda e pós-aguda mediante escalas funcionais e cognitivas, como Mini-Mental State Examination (MMSE), Montreal Cognitive Assessment (MoCA), Modified Rankin Scale (mRS), e Clinical Assessment Scale in Autoimmune Encephalitis (CASE). Conclusão Esta pesquisa oferece evidências tangíveis do manejo efetivo de pacientes com EAIs no sistema de saúde Brasileiro. (EAIs gliais subagudos movimento jovem prognóstico ABN (ABN SBNI, SBNI , (SBNI) Delphi 2 infantis participar LCR (LCR tissuebased tissue based assay TBA inglês cellbased cell CBA inglês. . antimyelin anti myelin glycoprotein antiMOG, antiMOG MOG, MOG anti-MOG IGIV (IGIV plasmaférese ciclofosfamida sintomáticas NmetilDaspartato N metil D aspartato antiNmethylDaspartate methyl aspartate receptor antiNMDAR, antiNMDAR NMDAR, NMDAR anti-NMDAR inglês, usados pósaguda pós cognitivas MiniMental Mini Mental MMSE, MMSE (MMSE) MoCA, MoCA (MoCA) mRS, mRS (mRS) CASE. CASE (CASE) Brasileiro (SBNI (MMSE (MoCA (mRS (CASE

Abstract Background Autoimmune encephalitis (AIE) is a group of inflammatory diseases characterized by the presence of antibodies against neuronal and glial antigens, leading to subacute psychiatric symptoms, memory complaints, and movement disorders. The patients are predominantly young, and delays in treatment are associated with worse prognosis. Objective With the support of the Brazilian Academy of Neurology (Academia Brasileira de Neurologia, ABN) and the Brazilian Society of Child Neurology (Sociedade Brasileira de Neurologia Infantil, SBNI), a consensus on the diagnosis and treatment of AIE in Brazil was developed using the Delphi method. Methods A total of 25 panelists, including adult and child neurologists, participated in the study. Results The panelists agreed that patients fulfilling criteria for possible AIE should be screened for antineuronal antibodies in the serum and cerebrospinal fluid (CSF) using the tissue-based assay (TBA) and cell-based assay (CBA) techniques. Children should also be screened for anti-myelin oligodendrocyte glucoprotein antibodies (anti-MOG). Treatment should be started within the first 4 weeks of symptoms. The first-line option is methylprednisolone plus intravenous immunoglobulin (IVIG) or plasmapheresis, the second-line includes rituximab and/or cyclophosphamide, while third-line treatment options are bortezomib and tocilizumab. Most seizures in AIE are symptomatic, and antiseizure medications may be weaned after the acute stage. In anti-N-methyl-D-aspartate receptor (anti-NMDAR) encephalitis, the panelists have agreed that oral immunosuppressant agents should not be used. Patients should be evaluated at the acute and postacute stages using functional and cognitive scales, such as the Mini-Mental State Examination (MMSE), the Montreal Cognitive Assessment (MoCA), the Modified Rankin Scale (mRS), and the Clinical Assessment Scale in Autoimmune Encephalitis (CASE). Conclusion The present study provides tangible evidence for the effective management of AIE patients within the Brazilian healthcare system. (AIE antigens symptoms complaints disorders young prognosis Academia ABN Sociedade Infantil SBNI, SBNI , SBNI) method 2 neurologists CSF (CSF tissuebased tissue based TBA (TBA cellbased cell CBA (CBA techniques antimyelin anti myelin antiMOG. antiMOG MOG . (anti-MOG) firstline line IVIG (IVIG plasmapheresis secondline second andor cyclophosphamide thirdline third tocilizumab symptomatic stage antiNmethylDaspartate N methyl D aspartate antiNMDAR NMDAR (anti-NMDAR used scales MiniMental Mini Mental MMSE, MMSE (MMSE) MoCA, MoCA (MoCA) mRS, mRS (mRS) CASE. CASE (CASE) system (anti-MOG (MMSE (MoCA (mRS (CASE

https://doi.org/10.1055/s-0044-1788586

Detection and quantification of Dioctophyme renale eggs in dog urine after nephrectomy
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Perera, Soliane Carra

; da Silva, Maria Antonieta Machado Pereira

; Capella, Gabriela de Almeida

; Pinheiro, Natália Berne

; Berne, Maria Elisabeth Aires

; Rappeti, Josaine Cristina da Silva

; Braga, Fabrício de Vargas Arigony

; Cleff, Marlete Brum

Revista Brasileira de Parasitologia Veterinária

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2024, Volume 33 N. 4 elocation e016224

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Dioctophyme renale é um nematódeo zoonótico que parasita principalmente o rim direito de caninos domésticos e silvestres, podendo parasitar também humanos, sendo seus ovos eliminados pela urina. É desconhecido o período de disseminação de ovos após o tratamento cirúrgico, assim o objetivo desse trabalho foi verificar, quantificar e acompanhar o tempo de eliminação de ovos de D. renale na urina de cães, após a remoção cirúrgica dos nematódeos. O estudo envolveu 15 cães com parasitismo renal por fêmeas de D. renale. Coletou-se amostras de urina antes da cirurgia e durante 10 dias após a nefrectomia, preconizando-se a primeira urina da manhã. Para a quantificação dos ovos, analisou-se 40 µL do sedimento urinário em triplicata. Nas análises laboratoriais, detectou-se entre 900 e > 6.000 ovos/amostra de urina em 86,7% dos cães antes da cirurgia, e em 40% dos cães no primeiro dia após o procedimento. Catorze cães (93,3%) eliminaram ovos de D. renale entre o primeiro e o décimo dia após a nefrectomia, sendo o maior pico de eliminação no primeiro dia. A partir desses resultados, observou-se que os cães podem eliminar ovos de D. renale, mesmo após a remoção dos helmintos do rim parasitado, destacando-se o ineditismo e a importância desses achados para a Saúde Única. silvestres humanos cirúrgico verificar D nematódeos 1 Coletouse Coletou se nefrectomia preconizandose preconizando manhã analisouse analisou 4 triplicata laboratoriais detectouse detectou 90 6000 6 000 6.00 ovosamostra amostra 867 86 7 86,7 procedimento 93,3% 933 93 3 (93,3% resultados observouse observou parasitado destacandose destacando Única 9 600 00 6.0 8 86, 93,3 (93,3 60 0 6. 93, (93, (93 (9 (

Abstract Dioctophyme renale is a zoonotic nematode that parasitizes mainly right kidney of domestic and wild canines, and can affect humans, and its eggs are eliminated in urine. The duration of egg dissemination after surgical treatment is unknown. Therefore, the objective of this study was to identify, quantify, and verify the duration of the elimination of D. renale eggs in dog urine after the surgical removal of nematodes. The study involved 15 dogs in which female specimens of D. renale were detected in kidneys. Urine samples, preferably first-morning urine samples, were collected before and for the first ten days after nephrectomy. For egg quantification, 40 µL samples of urinary sediment were analyzed in triplicate. In laboratory analyses, between 900 and > 6,000 eggs/urine sample were detected in 86.7% of the dogs prior to surgery, and in 40% of the dogs on postoperative day 1. Of the 15 dogs evaluated, 14 (93.3%) eliminated D. renale eggs on each of the first ten postoperative days. Egg elimination peaked on postoperative day 1. Our results indicate that dogs can continue to be sources of D. renale infection even after the helminths have been removed from a parasitized kidney, underscoring the novelty of these findings and their importance for the One Health approach. canines humans unknown Therefore identify quantify D nematodes 1 kidneys firstmorning morning nephrectomy quantification 4 triplicate analyses 90 6000 6 000 6,00 eggsurine 867 86 7 86.7 surgery evaluated 93.3% 933 93 3 (93.3% approach 9 600 00 6,0 8 86. 93.3 (93.3 60 0 6, 93. (93. (93 (9 (

https://doi.org/10.1590/s1984-29612024067

Delineamento e Racional do Estudo Rosa dos Ventos: Estudo Multicêntrico do Tipo Coorte de Pacientes com Insuficiência Cardíaca com Fração de Ejeção Reduzida ou Moderadamente Reduzida no Brasil Ventos
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Freitas, Dhayn Cassi de Almeida

; da Costa, Larissa Maria de Paula Rebouças

; Nadruz Jr., Wilson

; Marcondes-Braga, Fabiana G.

; Vieira, Jefferson Luis

; Bernardez-Pereira, Sabrina

; Barbosa Neto, Wilson Rodrigues

; Alves, Silvia Marinho Martins

; Wanderley, Gabriela Arcoverde

; Lira, Camila Nogueira Leandro

; Terui, Lucas Yugi de Souza

; Silva, Ana Luísa Guedes de França e

; Castro, Alana de Oliveira

; Freitas Jr., Aguinaldo F.

; de Figueiredo Neto, José Albuquerque

; Lopes, Renato D.

; Fernandes-Silva, Miguel Morita

; Silvestre, Odilson Marcos

Arquivos Brasileiros de Cardiologia

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2024, Volume 121 N. 10 elocation e20240120

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Fundamento: O Brasil é um país com diferentes biomas e desigualdades sociais. Existem poucos dados disponíveis sobre as diferenças regionais e o prognóstico da insuficiência cardíaca (IC) no país. Objetivo: O estudo Rosa dos Ventos tem como objetivo investigar as diferenças regionais e o prognóstico atual de pacientes com IC com fração de ejeção reduzida ou moderadamente reduzida no Brasil. Métodos: Este é um estudo prospectivo, multicêntrico, observacional, do tipo coorte que incluirá pacientes ambulatoriais com idade superior a 18 anos com IC e fração de ejeção < 50% em 30 centros privados distribuídos nas regiões brasileiras. Um total de 2500 pacientes serão incluídos entre junho de 2021 e outubro de 2023, com um período de 12 meses de seguimento. Coletaremos dados sobre status clínico e socioeconômico, prescrição médica e resultados de exames cardiológicos. Serão realizados telefonemas para o seguimento dos pacientes seis e 12 meses após a inclusão para coleta de informações sobre visitas ao departamento de emergência, internações e mortalidade. Conclusão: O estudo Rosa dos Ventos permitirá uma caracterização mais precisa da IC crônica no Brasil. Essa iniciativa proverá informações relevantes para o desenvolvimento de estratégias de manejo efetivas para mitigar o impacto dessa condição sobre os pacientes e o sistema de saúde. Fundamento sociais (IC Objetivo Métodos prospectivo multicêntrico observacional 1 50 3 brasileiras 250 202 2023 socioeconômico cardiológicos emergência mortalidade Conclusão saúde 5 25 20 2

Abstract Background: Brazil is a country with different biomes and social disparities. There are limited data available on regional differences and prognosis of heart failure (HF) in the country. Objective: The Rosa dos Ventos study aims to investigate regional differences and the current prognosis of HF outpatients with reduced or mildly reduced ejection fraction in Brazil. Methods: This is a prospective, multicenter, observational cohort study that will include outpatients older than 18 years with HF and an ejection fraction < 50% in 30 public and private centers distributed in all Brazilian regions. A total of 2,500 patients will be enrolled from June 2021 and October 2023, with a 12-month follow-up period. We will collect data on socioeconomic and clinical status, medical prescription and results of cardiology tests. Follow-up phone calls will be made at 6 and 12 months after inclusion to collect information regarding emergency room visits, hospitalization and mortality. Conclusion: The Rosa dos Ventos study will allow a more accurate characterization of chronic HF in Brazil. This initiative will provide relevant information for the development of effective management strategies to mitigate the impact of this condition on patients and the healthcare system. Background disparities (HF Objective Methods prospective multicenter 1 50 3 regions 2500 2 500 2,50 202 2023 12month month followup follow up period status tests Followup Follow visits mortality Conclusion system 5 250 2,5 20 25 2,

https://doi.org/10.36660/abc.20240120

Clinical Presentation and Risk Factors for Molar-Incisor and Second Primary Molar Hypomineralization: A Cross-Sectional Study MolarIncisor Incisor Hypomineralization CrossSectional Cross Sectional
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Rosa, Thamirys da Costa

; Silva, Fernanda Mafei Felix da

; Vieira, Fernanda Gabriela de Fátima

; Vieira, Alexandre Rezende

; Gonçalves, Andrea Fonseca

; Costa, Marcelo de Castro

; Neves, Aline de Almeida

Pesquisa Brasileira em Odontopediatria e Clínica Integrada

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2024, Volume 24 elocation e230066

Abstract: En | Text: En | PDF: En

ABSTRACT Objective: To identify the clinical presentation of molar incisor hypomineralization (MIH) and hypomineralization of second primary molars (HSPM), including the distribution patterns of presence and severity of lesions, and to investigate the association of risk factors during the pre-and postnatal period with the presence of lesions. Material and Methods: This cross-sectional study was conducted with 160 individuals (72 with MIH/HSPM and 88 without lesions). The symmetry analysis regarding the presence and severity of MIH/HSPM was evaluated in pairs of homologous and opposite teeth. Sociodemographic and medical information was obtained using a detailed questionnaire. Data were analyzed by means of chi-square tests, Student’s t-test, and logistic regression (p<0.05). Results: Symmetry of presence and severity of hypomineralization lesions were present in homologous permanent teeth in 53.8% and 70.5% of cases, respectively, with statistically significant results only for the symmetrical pattern of severity of MIH lesions in the maxillary first molars (p=0.016) and mandibular first molars (p=0.02). Otherwise, a non-symmetric presence was statistically significant in homologous second primary molars (p=0.002) and opposite primary and permanent teeth (p≤0.001). An association between MIH/HSPM and systemic diseases during pregnancy and children medication was found (p<0.05); however, no evidence was found between these and MIH/HSPM severity. Conclusion: The symmetric pattern of severity of MIH lesions was statistically significant in permanent homologous teeth. Risk factors during pre and postnatal periods may be related to MIH/HSPM; however, these do not seem to interact with severity. Objective (MIH HSPM, HSPM , (HSPM) preand Methods crosssectional cross sectional 16 72 (7 MIHHSPM 8 . lesions) questionnaire chisquare chi square tests Students Student s ttest, ttest t test, test t-test p<0.05. p005 p p<0.05 0 05 (p<0.05) Results 538 53 53.8 705 70 5 70.5 cases respectively p=0.016 p0016 016 (p=0.016 p=0.02. p002 p=0.02 02 (p=0.02) Otherwise nonsymmetric non p=0.002 p0002 002 (p=0.002 p≤0.001. p0001 p≤0.001 001 (p≤0.001) however Conclusion (HSPM 1 7 ( p00 p<0.0 (p<0.05 53. 70. p=0.01 p001 01 (p=0.01 p=0.0 (p=0.02 p=0.00 p000 00 (p=0.00 p≤0.00 (p≤0.001 p0 p<0. (p<0.0 (p=0.0 p=0. p≤0.0 (p≤0.00 p<0 (p<0. (p=0. p=0 p≤0. (p≤0.0 p< (p<0 (p=0 p= p≤0 (p≤0. (p< (p= p≤ (p≤0 (p (p≤

https://doi.org/10.1590/pboci.2024.072

Posicionamento do Departamento de Imagem Cardiovascular da Sociedade Brasileira de Cardiologia sobre o Uso do Strain Miocárdico na Rotina do Cardiologista – 2023 202 20 2
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Almeida, André Luiz Cerqueira

; Melo, Marcelo Dantas Tavares de

; Bihan, David Costa de Souza Le

; Vieira, Marcelo Luiz Campos

; Pena, José Luiz Barros

; Del Castillo, José Maria

; Abensur, Henry

; Hortegal, Renato de Aguiar

; Otto, Maria Estefania Bosco

; Piveta, Rafael Bonafim

; Dantas, Maria Rosa

; Assef, Jorge Eduardo

; Beck, Adenalva Lima de Souza

; Santo, Thais Harada Campos Espirito

; Silva, Tonnison de Oliveira

; Salemi, Vera Maria Cury

; Rocon, Camila

; Lima, Márcio Silva Miguel

; Barberato, Silvio Henrique

; Rodrigues, Ana Clara

; Rabschkowisky, Arnaldo

; Frota, Daniela do Carmo Rassi

; Gripp, Eliza de Almeida

; Barretto, Rodrigo Bellio de Mattos

; Silva, Sandra Marques e

; Cauduro, Sanderson Antonio

; Pinheiro, Aurélio Carvalho

; Araujo, Salustiano Pereira de

; Tressino, Cintia Galhardo

; Silva, Carlos Eduardo Suaide

; Monaco, Claudia Gianini

; Paiva, Marcelo Goulart

; Fisher, Cláudio Henrique

; Alves, Marco Stephan Lofrano

; Grau, Cláudia R. Pinheiro de Castro

; Santos, Maria Veronica Camara dos

; Guimarães, Isabel Cristina Britto

; Morhy, Samira Saady

; Leal, Gabriela Nunes

; Soares, Andressa Mussi

; Cruz, Cecilia Beatriz Bittencourt Viana

; Guimarães Filho, Fabio Villaça

; Assunção, Bruna Morhy Borges Leal

; Fernandes, Rafael Modesto

; Saraiva, Roberto Magalhães

; Tsutsui, Jeane Mike

; Soares, Fábio Luis de Jesus

; Falcão, Sandra Nívea dos Reis Saraiva

; Hotta, Viviane Tiemi

; Armstrong, Anderson da Costa

; Hygidio, Daniel de Andrade

; Miglioranza, Marcelo Haertel

; Camarozano, Ana Cristina

; Lopes, Marly Maria Uellendahl

; Cerci, Rodrigo Julio

; Siqueira, Maria Eduarda Menezes de

; Torreão, Jorge Andion

; Rochitte, Carlos Eduardo

; Felix, Alex

Arquivos Brasileiros de Cardiologia

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dec 2023, Volume 120 N. 12 elocation e20230646

Abstract: Pt | Text: Pt | PDF: Pt

https://doi.org/10.36660/abc.20230646

Impact of Telemedicine use on clinical care indicators of pediatric intensive care units: protocol for a cluster randomized clinical trial units
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Silva, Mariana Motta Dias da

; Klever, Emanuele König

; Rocha, Jacqueline Castro da

; Silva, Gabriela de Oliveira Laguna

; Amorim, Jerusa da Rocha de

; Dode, Andressa Dutra

; Simionato, Bárbara Marina

; Cunha, Luciane Gomes da

; Zaupa, Ana Paula Berni

; Krauzer, João Ronaldo Mafalda

; Pires, Aristóteles de Almeida

; Cabral, Felipe Cezar

; Moreira, Tais de Campos

; Constant, Hilda Maria Rodrigues Moleda

Critical Care Science

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sep 2023, Volume 35 N. 3 Pages 266 - 272

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO O objetivo deste estudo será apresentar o protocolo de um ensaio clínico randomizado em cluster a ser realizado por meio do projeto TeleUTI - Qualificação da Assistência em Terapia Intensiva por Telemedicina. O estudo consistirá em um ensaio clínico randomizado por cluster, open label, em unidades de terapia intensiva pediátricas, com proporção de alocação de 1:1, com o intuito de comparar o grupo de intervenção (apoio da telemedicina para os pacientes internados na unidade de terapia intensiva pediátrica) com um grupo controle (cuidados habituais da unidade de terapia intensiva pediátrica). O estudo se propõe a selecionar 16 unidades de terapia intensiva pediátricas, incluindo 100 participantes por local, com o total de 1.600 participantes. O grupo intervenção receberá telerounds de segunda-feira a sexta-feira e terá à disposição especialistas e atividades de educação continuada. O desfecho primário a ser avaliado será o tempo de permanência nas unidades de terapia intensiva pediátricas, definido pela diferença entre a data de alta do participante com a data de admissão na unidade de terapia intensiva. Os desfechos secundários serão: taxa de mortalidade; dias livres de ventilação mecânica, dias de uso de antibióticos, dias de uso de drogas vasoativas e dias de uso de sedoanalgesia. Este estudo será conduzido em conformidade com a resolução 466/12 do Conselho Nacional de Saúde, com aprovação pelo Comitê de Ética em Pesquisa das instituições hospitalares envolvidas. O trabalho tem o potencial de reproduzir estudos sobre Telemedicina em cuidados intensivos, podendo trazer contribuições importantes ao atendimento em unidades de terapia intensiva no Brasil e em outras realidades. Se a Telemedicina mostrar resultados clínicos assistenciais positivos em relação ao tratamento convencional, mais pacientes pediátricos poderão ser beneficiados. Registro ClinicalTrials.gov: NCT05260710 label pediátricas 11, 11 1 1, 1:1 apoio pediátrica pediátrica. . 10 local 1600 600 1.60 segundafeira segunda feira sextafeira sexta continuada serão mortalidade mecânica antibióticos sedoanalgesia 46612 466 12 466/1 Saúde envolvidas intensivos realidades convencional beneficiados ClinicalTrials.gov ClinicalTrialsgov ClinicalTrials gov NCT NCT0526071 1: 160 60 1.6 4661 46 466/ NCT052607 6 1. 4 NCT05260 NCT0526 NCT052 NCT05 NCT0

ABSTRACT The objective of this study is to present the protocol of a cluster randomized clinical trial to be conducted through the TeleICU project - Qualification of Intensive Care by Telemedicine. The study will consist of a cluster randomized clinical trial, open label, in pediatric intensive care units, with an allocation ratio of 1:1, to compare the intervention group (support of Telemedicine for patients admitted to the pediatric intensive care unit) with a control group (pediatric intensive care unit usual care). The study proposed to select 16 pediatric intensive care units, including 100 participants per site, with a total of 1,600 participants. The intervention group will receive telerounds from Monday to Friday and will have specialists and continuing education activities available. The primary outcome measure will be the length of stay in the pediatric intensive care unit, defined as the difference between the date of discharge of the participant and the date of admission to the intensive care unit. The secondary outcomes will be mortality rate, invasive mechanical ventilation-free days, days using antibiotics, days using vasoactive drugs and days using sedoanalgesia. This study will be conducted in accordance with Resolution 466/12 of the National Health Council, with approval by the Research Ethics Committee of the institutions involved. The present study has the potential to reproduce studies on Telemedicine in intensive care and may make important contributions to care in intensive care units in Brazil and other settings. If Telemedicine shows positive clinical care results compared to conventional treatment, more pediatric patients may benefit. ClinicalTrials.gov registry: NCT05260710 label 11, 11 1 1, 1:1 support care. . care) 10 site 1600 600 1,60 available rate ventilationfree ventilation free antibiotics sedoanalgesia 46612 466 12 466/1 Council involved settings treatment benefit ClinicalTrialsgov ClinicalTrials gov registry NCT NCT0526071 1: 160 60 1,6 4661 46 466/ NCT052607 6 4 NCT05260 NCT0526 NCT052 NCT05 NCT0

https://doi.org/10.5935/2965-2774.20230223-en

Evaluation of the effect of physical exercise interventions in Primary Health Care in Brazil on cardiometabolic risk factors: a systematic review factors
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Brunheroti, Karina de Almeida

; Brito, Bruna Thais Gomes de

; Silva, Ana Flávia Andalécio Couto da

; Castro, Gabriela Lima de

; Viana, Rebeca Baptista Fonseca

; Barbosa, Luis Fabiano

; Puga, Guilherme Morais

; Andaki, Alynne Christian Ribeiro

; Papini, Camila Bosquiero

Revista Brasileira de Cineantropometria & Desempenho Humano

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2023, Volume 25 elocation e86876

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo O objetivo foi buscar sistematicamente e sintetizar as evidências disponíveis na literatura acerca do efeito de intervenções com exercício físico na Atenção Primária à Saúde (APS), realizadas no Brasil, sobre os fatores de risco cardiometabólicos. A busca sistemática foi realizada nas bases de dados PubMed, Biblioteca Virtual em Saúde e Web of Science. Foram incluídos estudos com intervenção de AF ou exercício na APS; realizadas no Brasil; com população >18 anos de idade; pelo menos um fator de risco cardiometabólico avaliado pré e pós intervenção. Utilizou-se o Descritores em Ciências da Saúde para definir os descritores de busca: “physical activity” OR “exercise” OR “motor activity” AND “primary health care” OR “health centers” OR “primary care” AND “Brazil”. As fases de seleção foram realizadas por pares e com cegamento e os conflitos decididos por um terceiro avaliador. Utilizou-se a escala de Jadad para avaliar a qualidade metodológica dos artigos incluídos. Foram encontrados 1.817 artigos e excluídas 26 duplicatas, restando 1.791 para leitura dos títulos. Foram lidos 105 resumos e 53 artigos na íntegra. Por fim, 06 artigos foram considerados elegíveis e incluídos na revisão. Os fatores de risco cardiometabólicos avaliados nos estudos incluídos foram índice de massa corporal (4 estudos), razão cintura quadril (1 estudo), percentual de gordura (1 estudo), pressão arterial (2 estudos), perfil lipídico (1 estudo), perfil inflamatório (1 estudo) e capacidade aeróbica (3 estudos). Conclui-se que não há evidências suficientes na literatura sobre o efeito das intervenções de exercícios na APS com foco nos fatores de risco cardiometabólicos. APS, , (APS) Brasil PubMed Science 18 >1 idade Utilizouse Utilizou se physical activity exercise “exercise motor primary care centers Brazil. Brazil . “Brazil” avaliador 1817 1 817 1.81 2 duplicatas 1791 791 1.79 títulos 10 5 íntegra fim 0 revisão 4 ( estudos, estudos) estudo, estudo 3 estudos. Concluise Conclui (APS > “Brazil 181 81 1.8 179 79 1.7 8 1. 17 7

Abstract The objective was to systematically search and synthesize the evidence available in the literature about the effect of physical exercise interventions Primary Health Care (PHC), carried out in Brazil, on cardiometabolic risk factors. The search was performed in the PubMed, Virtual Health Library and Web of Science databases. The inclusion criteria were: studies with physical activity (PA) interventions or exercise in PHC; carried out in Brazil; population aged >18 years; at least one cardiometabolic risk factor assessed pre and post-intervention. The “Health Sciences Descriptors” were used to define the search descriptors: “physical activity” OR “exercise” OR “motor activity” AND “primary health care” OR “health centers” OR “primary care” AND “Brazil”. The selection phases were performed by pairs of blinded researchers and the conflicts were decided by a third evaluator. Jadad scale was used to assess the methodological quality of the articles included. In total, 1,817 articles were found and 26 duplicates excluded, leaving 1,791 for reading of titles. The abstracts of 105 articles were read, and 53 articles were read in full. Finally, 06 articles were considered eligible and included in the review. The cardiometabolic risk factors evaluated in the included studies were body mass index (4 studies), waist-hip ratio (1 study), fat percentage (1 study), blood pressure (2 studies), lipid profile (1 study), inflammatory profile (1 study), and aerobic capacity (3 studies). It is concluded that there is insufficient evidence in the literature about the effect of exercise interventions in PHC with a focus on cardiometabolic risk factors. PHC, , (PHC) Brazil PubMed databases PA (PA 18 >1 years postintervention. postintervention post intervention. intervention post-intervention Descriptors descriptors “exercise motor primary care centers Brazil. . “Brazil” evaluator total 1817 1 817 1,81 2 excluded 1791 791 1,79 titles 10 5 full Finally 0 review 4 ( studies, studies) waisthip waist hip study, study study) 3 studies. (PHC > “Brazil 181 81 1,8 179 79 1,7 8 1, 17 7

https://doi.org/10.1590/1980-0037.2023v25e86876

10.

A Rede de Atenção às Urgências e Emergências no Brasil: revisão integrativa da literatura Brasil
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Tofani, Luís Fernando Nogueira

; Furtado, Lumena Almeida Castro

; Andreazza, Rosemarie

; Bigal, André Luiz

; Feliciano, Deize Graziele Conceição Ferreira

; Silva, Gabriela Rodrigues da

; Chioro, Arthur

Saúde e Sociedade

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2023, Volume 32 N. 1 elocation e220122pt

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo A Rede de Atenção às Urgências e Emergências (RUE) foi proposta enquanto política pública com a finalidade de articular e integrar os serviços assistenciais do Sistema Único de Saúde (SUS), ampliando e qualificando o acesso dos usuários em situação de urgência e emergência em saúde de forma ágil e oportuna. Este estudo tem como objetivo analisar a produção científica sobre a política da RUE no Brasil e elaborar sínteses demonstrando seus limites e desafios. Utilizou-se como método a revisão integrativa de literatura, a partir da busca de artigos nas bases de dados LILACS, SciELO e MEDLINE e de dissertações e teses na plataforma virtual da Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (Capes). A pesquisa possibilitou a análise de 34 estudos do campo da saúde coletiva, com enfoque nos diferentes serviços de urgência e a integração entre eles, incluindo possíveis transformações no processo de cuidado em saúde e distintas estratégias de avaliação, por meio de diferentes abordagens, principalmente qualitativas. São observadas fragilidades na articulação em rede, com manutenção da centralidade do componente hospitalar e o poder de seu capital simbólico, ficando a Atenção Básica relegada ao campo discursivo. (RUE SUS, SUS , (SUS) oportuna desafios Utilizouse Utilizou se literatura LILACS Capes. Capes . (Capes) 3 coletiva eles avaliação abordagens qualitativas rede simbólico discursivo (SUS (Capes

Abstract The Urgent and Emergency Care Network (RUE) was proposed in Brazil as a public policy to articulate and integrate the health services of the Brazilian National Health System (SUS), expanding and qualifying the access of users in e emergency health situations in an efficient and timely manner. This study analyzes the scientific production on the RUE in Brazil and elaborates summaries showing the limits and challenges of this health policy. An integrative literature review was used as a method, based on the search for articles in the LILACS, SciELO, and MEDLINE databases and for dissertations and theses on the virtual platform of the Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES). The investigation enabled the analysis of 34 studies in the field of collective health, focused on the different emergency services and the integration between them, including possible changes in the health care process and different evaluation strategies, by using different approaches, mainly qualitative. Weaknesses are observed in the network articulation, maintaining the centrality of hospital services and the power of its symbolic capital, with primary care being relegated to the discursive field. (RUE SUS, SUS , (SUS) manner method LILACS SciELO CAPES. CAPES . (CAPES) 3 them strategies approaches qualitative articulation capital (SUS (CAPES

https://doi.org/10.1590/s0104-12902023220122pt

11.

A Rede de Atenção às Urgências e Emergências no Brasil: revisão integrativa da literatura
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Tofani, Luís Fernando Nogueira

; Furtado, Lumena Almeida Castro

; Andreazza, Rosemarie

; Bigal, André Luiz

; Feliciano, Deize Graziele Conceição Ferreira

; Silva, Gabriela Rodrigues da

; Chioro, Arthur

Saúde e Sociedade

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2023, Volume 32 N. 1 elocation e220122pt

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

https://doi.org/10.1590/s0104-12902023220122pt

12.

Manejo del síndrome antifosfolipídico trombótico: ¿Anticoagulantes directos orales o Warfarina?
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Buendía Palacios, Diana Cristina

; de Almeida Vasconcelos, Jéssica Gabriela

; Freitas Silva, João André

; Picón-Jaimes, Yelson Alejandro

; Mérola, Valentina

Revista Uruguaya de Medicina Interna

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2023, Volume 8 N. 2 Pages 69 - 71

Abstract: Es | Text: Es | PDF: Es

https://doi.org/10.26445/08.02.7

13.

Getting knowledge to provide care: prevalence and factors associated with Sexually Transmitted Infections in immigrants from Goiás care
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Silva, Carla de Almeida

; Silva, Grazielle Rosa da Costa

; Martins, Thaynara Lorrane Silva

; Moura, Winny Éveny Alves

; Gomes, Davi Oliveira

; Bandeira, Gabriela Nolasco

; Carneiro, Megmar Aparecida dos Santos

; Gonzalez, Roxana Isabel Cardozo

; Pacheco, Leonora Rezende

; Zanchetta, Margareth Santos

; Lima, Juliana de Oliveira Roque e

; Teles, Sheila Araujo

; Caetano, Karlla Antonieta Amorim

Revista da Escola de Enfermagem da USP

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2023, Volume 57 N. spe elocation e20230034

Abstract: Pt En Es | Text: Pt En Es | PDF: Pt | PDF: En | PDF: Es

RESUMO Objetivo: Estimar a prevalência de Infecções Sexualmente Transmissíveis (IST) em imigrantes e refugiados residentes na região metropolitana de Goiânia, Goiás. Método: Trata-se de um estudo transversal e analítico. A coleta de dados foi realizada no período de julho de 2019 a janeiro de 2020 e integraram a amostra 308 imigrantes e refugiados. Todos foram entrevistados face-a-face e testados para HIV, Sífilis e Hepatite B, por meio de testes rápidos. Resultados: A prevalência geral para alguma das IST investigadas foi de 8,8% (IC95% 6,0% – 12,3%), sendo 5,8% (IC95% 3,6% – 8,9%) para Hepatite B, 2,3% para Sífilis (IC95% 1,00% – 4,4%) e 0,7% para HIV (IC95% 0,1% – 2,1%). A análise múltipla, por regressão logística, mostrou que as variáveis sexo masculino (OR = 2,7) e tempo de moradia no Brasil (OR = 2,6) foram associadas significativamente às IST (p < 0,05). Conclusão: Os resultados deste estudo sugerem que as IST são um problema de saúde em imigrantes/refugiados, que parecem ser exacerbadas com o tempo de migração no país. Políticas públicas que garantam a assistência à saúde dessa população devem ser consideradas. Objetivo (IST Goiânia Goiás Método Tratase Trata se analítico 201 202 30 faceaface face B rápidos Resultados 88 8 8,8 IC95% IC95 IC (IC95 60 6 0 6,0 12,3%, 123 12,3% , 12 3 12,3%) 58 5 5,8 36 3,6 8,9% 89 9 23 2 2,3 100 1 00 1,00 4,4% 44 4 07 7 0,7 01 0,1 2,1%. 21 2,1% . 2,1%) múltipla logística OR 2,7 27 2,6 26 p 0,05. 005 0,05 05 0,05) Conclusão imigrantesrefugiados imigrantes/refugiados país consideradas 20 8, IC9 (IC9 6, 12,3 5, 3, 8,9 2, 10 1,0 4,4 0, 2,1 0,0 (IC 12, 1, 4,

ABSTRACT Objective: To estimate the prevalence of Sexually Transmitted Infections (STIs) in immigrants and refugees living in the metropolitan region of Goiânia, Goiás. Method: This is a cross-sectional and analytical study. Data collection was carried out from July 2019 to January 2020 and 308 immigrants and refugees were included in the sample. All were underwent face-to-face interviews and were tested for HIV, Syphilis, and Hepatitis B, using rapid tests. Results: The general prevalence for any of the STIs investigated was 8.8% (95%CI 6.0% – 12.3%), being 5.8% (95%CI 3.6% – 8.9%) for Hepatitis B, 2.3% for Syphilis (95%CI 1.00% – 4.4%) and 0.7% for HIV (95%CI 0.1% – 2.1%). Multiple analysis, using logistic regression, showed that the variables male gender (OR = 2.7) and length of time living in Brazil (OR = 2.6) were significantly associated with STIs (p < 0.05). Conclusion: The results of this study suggest that STIs are a health problem in immigrants/refugees, which appear to be enhanced with the length of migration in the country. Public policies that guarantee health care for this population shall be considered. Objective (STIs Goiânia Goiás Method crosssectional cross sectional 201 202 30 sample facetoface face B tests Results 88 8 8.8 95%CI 95CI CI 95 60 6 0 6.0 12.3%, 123 12.3% , 12 3 12.3%) 58 5 5.8 36 3.6 8.9% 89 9 23 2 2.3 100 1 00 1.00 4.4% 44 4 07 7 0.7 01 0.1 2.1%. 21 2.1% . 2.1%) analysis regression OR 2.7 27 2.6 26 p 0.05. 005 0.05 05 0.05) Conclusion immigrantsrefugees immigrants/refugees country considered 20 8. 6. 12.3 5. 3. 8.9 2. 10 1.0 4.4 0. 2.1 0.0 12. 1. 4.

RESUMEN Objetivo: Estimar la prevalencia de Enfermedades de Transmisión Sexual (ETS) en inmigrantes y refugiados residentes en la región metropolitana de Goiânia, Goiás. Método: Se trata de un estudio transversal y analítico. La recolección de datos se llevó a cabo desde julio de 2019 hasta enero de 2020 y se incluyeron en la muestra 308 inmigrantes y refugiados. Todos fueron entrevistados cara a cara y sometidos a pruebas de VIH, Sífilis y Hepatitis B, mediante pruebas rápidas.. Resultados: La prevalencia general para cualquiera de las ETS investigadas fue de 8,8% (IC95% 6,0% – 12,3%), siendo 5,8% (IC95% 3,6% – 8,9%) para Hepatitis B, 2,3% para Sífilis (IC95% 1,00% – 4,4%) y 0,7% para VIH (IC95% 0,1% – 2,1%). El análisis múltiple, mediante regresión logística, mostró que las variables género masculino (OR = 2,7) y tiempo de residencia en Brasil (OR = 2,6) se asociaron significativamente con las ETS (p < 0,05). Conclusión: Los resultados de este estudio sugieren que las ETS son un problema de salud en inmigrantes/refugiados, que parecen exacerbarse con la duración de la migración en el país. Se deben considerar políticas públicas que garanticen la atención de la salud de esta población. Objetivo (ETS Goiânia Goiás Método analítico 201 202 30 B rápidas rápidas. Resultados 88 8 8,8 IC95% IC95 IC (IC95 60 6 0 6,0 12,3%, 123 12,3% , 12 3 12,3%) 58 5 5,8 36 3,6 8,9% 89 9 23 2 2,3 100 1 00 1,00 4,4% 44 4 07 7 0,7 01 0,1 2,1%. 21 2,1% . 2,1%) múltiple logística OR 2,7 27 2,6 26 p 0,05. 005 0,05 05 0,05) Conclusión inmigrantesrefugiados inmigrantes/refugiados país población 20 8, IC9 (IC9 6, 12,3 5, 3, 8,9 2, 10 1,0 4,4 0, 2,1 0,0 (IC 12, 1, 4,

https://doi.org/10.1590/1980-220x-reeusp-2023-0034en

14.

Ciência da disseminação e implementação em países de língua portuguesa: por que considerar? portuguesa considerar
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Sala, Danila Cristina Paquier

; Okuno, Meiry Fernanda Pinto

; Buccini, Gabriela

; Hankins, Jane Silva

; Câmara, Alice Barros

; Vieira, Ana Claudia

; Horta, Ana Lucia de Moraes

; Varela, Andrea Liliana Vesga

; Trapé, Carla Andrea

; Treichel, Carlos Alberto dos Santos

; Luizaga, Carolina Terra de Moraes

; Oliveira, Cintia de Freitas

; Luquine Jr, Cézar D

; Bonfim, Daiana

; Melo, Daiane Sousa

; Fatori, Daniel

; Bernardo, Debora

; Silva, Flávio Dias

; Paiva Neto, Francisco Timbó de

; Sousa, Girliani Silva de

; Relvas, Gláubia Rocha Barbosa

; Eshriqui, Ilana

; Chavez, Leidy Janeth Erazo

; Almeida, Leticia Yamawaka de

; Godoi, Lídia Pereira da Silva

; Belotti, Lorrayne

; Corrêa, Lucas Hernandes

; Cordeiro, Luciana

; Hespanhol, Luiz

; Juskevicius, Luize Fábrega

; Padoveze, Maria Clara

; Bueno, Mariana

; Siqueira, Marina Martins

; Bortoli, Maritsa Carla de

; Louvison, Marília Cristina Prado

; Cardoso, Marília Mastrocolla de Almeida

; Becker, Natália

; Tanaka, Oswaldo Yoshimi

; Costa, Paula Cristina Pereira da

; Bomfim, Rafael Aiello

; Luz, Reginaldo Adalberto

; Gimbel, Sarah

; Dias, Sónia

; Castral, Thaíla Corrêa

; Domingos, Thiago da Silva

; Baumann, Ana A.

Acta Paulista de Enfermagem

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2023, Volume 36 Suppl. 1 elocation eEDT01

Abstract: Pt | Text: Pt | PDF: Pt

https://doi.org/10.37689/acta-ape/2023edtspe01

15.

Effect of the cranberry ( Vaccinium macrocarpon ) juice on reducing dentin erosion: an in vitro study
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KATO, Melissa Thiemi

; CARDOSO, Cristiane de Almeida Baldini

; JORDÃO, Maisa Camillo

; GALVÃO, Renato Palhano de Oliveira

; ISCUISSATI, Ana Gabriela Silva

; KINOSHITA, Angela Mitie Otta

; BUZALAF, Marília Afonso Rabelo

Brazilian Oral Research

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2022, Volume 36 elocation e076

Abstract: En | Text: En | PDF: En

Abstract Vaccinium macrocarpon (cranberry) is a fruit that has an inhibitory effect on matrix metalloproteinases (MMPs) present in dentin and saliva. The inhibition of MMPs has been shown to prevent dentin erosion. The aim of this study was to analyze the effect of cranberry juice on the reduction of dentin erosion in vitro. Specimens of bovine dentin (4×4×2 mm) were randomized and divided into 4 groups (n = 17/group): distilled water (C-control, pH 7.2); green tea extract solution containing 400 µm epigallo-catechin-gallate (EGCg, positive control, pH 4.5); 10% cranberry extract (CrE, pH 3.9), and cranberry juice (CrJ, Cranberry JuxxTM, pH 2.8). Specimens were submitted to erosive pH cycles for 5 days. Each day, four demineralizations were carried out with 0.1% citric acid (90 s). After the acid challenges, specimens were rinsed and kept in treatment solutions for 1 min; afterwards, they were rinsed and stored in artificial saliva for 1 h at 37°C (or overnight at the end of each day). After the experimental period of 5 days, dentin loss was evaluated by contact profilometry. Data were analyzed by ANOVA and Tukey’s test (p < 0.05). Dentin loss (µm ± SD) was significantly lower for all treatments (EGCg = 9.93 ± 2.90; CrE = 12.10 ± 5.44; CrJ = 11.04 ± 5.70) compared to control (21.23 ± 11.96), but it did not significantly differ from each other. These results indicate that the commercial cranberry juice, despite its low pH, is able to reduce dentin erosion, which might be due to the ability of cranberry components to inhibit MMPs.

https://doi.org/10.1590/1807-3107bor-2022.vol36.0076

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