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ABSTRACT BACKGROUND: A bibliometric analysis covering only the production of original studies or considering world production until 2022 has yet to be conducted. The creation and advancement of vaccines have also influenced research priorities, demonstrating the need for a new approach to this subject. OBJECTIVES: To analyze worldwide scientific production related to coronavirus disease 2019 (COVID-19) and the aged and to describe what has already been produced. DESIGN AND SETTING: Bibliometric analysis with a quantitative approach. METHOD: The search terms “COVID-19,” “SARS-CoV-2,” “Aged,” and “Elderly” were used to retrieve articles from the Web of Science database. A total of 684 articles were included in the analysis. Data were imported into RStudio Desktop Software and linked to R Software. The Bibliometrix R package and VOSviewer software were used for analysis. RESULTS: Most articles were published in 2020. These were produced by 4,937 authors and published in 379 journals. The keyword most used by the authors was “COVID-19.” Publications from 77 countries were obtained. China had the highest article production ranking, and Spain collaborated the most. The articles addressed the implications of the pandemic on the aged, the relationship between vaccination in the aged, and the implications for the disease itself. CONCLUSION: Further research should be conducted, mainly concerning vaccines and vaccination of the aged, owing to the need for and importance of immunization in this risk group, including assessing the long-term effects of vaccines. BACKGROUND 202 conducted priorities subject OBJECTIVES 201 COVID19 COVID 19 (COVID-19 SETTING METHOD COVID19, 19, “COVID-19, SARSCoV2, SARSCoV2 SARSCoV SARS CoV 2, 2 “SARS-CoV-2, Aged, Aged “Aged, Elderly “Elderly database 68 RESULTS 2020 4937 4 937 4,93 37 journals COVID19. 19. “COVID-19. 7 obtained ranking itself CONCLUSION group longterm long term 20 COVID1 1 (COVID-1 “COVID-19 “SARS-CoV-2 “Aged 6 493 93 4,9 3 (COVID- “COVID-1 “SARS-CoV- 49 9 4, (COVID “COVID- “SARS-CoV “COVID

https://doi.org/10.1590/1516-3180.2022.0662.r1.190523

Clinical outcomes in newborns of pregnant women with COVID-19: integrative review COVID19 COVID 19 COVID-19 COVID1 1 COVID-1 COVID-
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Ximenes, Iara Bezerra da Silva

; Leal, Cassiano Richel Ferreira

; Batista, Odinéia Maria Amorim

; Moura, Maria Eliete Batista

; Madeira, Maria Zélia de Araújo

; Valle, Andreia Rodrigues Moura da Costa

; Prates, Pedro Emílio Gomes

; Sousa, Álvaro Francisco Lopes de

; Andrade, Denise de

Revista Brasileira de Enfermagem

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2024, Volume 77 Suppl. 1 elocation e20230400

Abstract: Pt En Es | Text: Pt En Es | PDF: Pt | PDF: En | PDF: Es

RESUMO Objetivos: analisar desfechos clínicos em recém-nascidos de mulheres grávidas com COVID-19. Métodos: revisão integrativa realizada no PubMed, Web of Knowledge, SCOPUS, CINHAL; foram obtidos 2.111 estudos, e 8 artigos compuseram a amostra final. Resultados: os desfechos clínicos em neonatos de mulheres grávidas positivas para COVID-19 foram classificados de acordo com as seguintes categorias: a) contaminação por COVID-19, relatada em 62,5% dos estudos; b) alta hospitalar devido à melhora, mencionada em 37,5% dos artigos; c) óbito, representando casos raros em 25% da amostra. A complicação gestacional mais prevalente foi prematuridade, mencionada em 75% dos estudos. Essa complicação foi observada devido a casos de ruptura prematura de membranas e descolamento de placenta. Conclusões: apesar do conhecimento do comportamento assintomático e levemente sintomático em neonatos, é importante continuar a busca por novos dados clínicos, pois esse público apresenta reações incertas à infecção por SARS-CoV-2. Objetivos recémnascidos recém nascidos COVID19. COVID19 COVID 19. 19 Métodos PubMed Knowledge SCOPUS CINHAL 2111 2 111 2.11 estudos final Resultados COVID-1 categorias COVID19, 19, 625 62 5 62,5 b melhora 375 37 37,5 c óbito 25 prematuridade 75 placenta Conclusões SARSCoV2. SARSCoV2 SARSCoV SARS CoV 2. SARS-CoV-2 COVID1 1 211 11 2.1 COVID- 6 62, 3 37, 7 SARS-CoV- 21 SARS-CoV

ABSTRACT Objectives: to analyze clinical outcomes in newborns of pregnant women with COVID-19. Methods: integrative review conducted in PubMed, Web of Knowledge, SCOPUS, CINHAL; 2,111 studies were obtained, and 8 articles comprised the final sample. Results: clinical outcomes in neonates of pregnant women positive for COVID-19 were classified according to the following categories: a) contamination by COVID-19, reported in 62.5% of the studies; b) hospital discharge due to improvement, mentioned in 37.5% of the articles; c) death, representing rare cases in 25% of the sample. The most prevalent gestational complication was prematurity, mentioned in 75% of the studies. This complication has been observed due to cases of premature rupture of membranes and placental abruption. Conclusions: despite the knowledge of asymptomatic and mildly symptomatic behavior in neonates, it is important to continue the search for new clinical data, as this public has uncertain reactions to SARS-CoV-2 infection. Objectives COVID19. COVID19 COVID 19. 19 Methods PubMed Knowledge SCOPUS CINHAL 2111 2 111 2,11 obtained sample Results COVID-1 categories a COVID19, 19, 625 62 5 62.5 b improvement 375 37 37.5 c death 25 prematurity 75 abruption Conclusions data SARSCoV2 SARSCoV SARS CoV SARS-CoV- infection COVID1 1 211 11 2,1 COVID- 6 62. 3 37. 7 SARS-CoV 21 2,

RESUMEN Objetivos: analizar los desenlaces clínicos en recién nacidos de mujeres embarazadas con COVID-19. Métodos: revisión integradora realizada en PubMed, Web of Knowledge, SCOPUS, CINHAL; se obtuvieron 2.111 estudios y 8 artículos conformaron la muestra final. Resultados: los desenlaces clínicos en neonatos de mujeres embarazadas positivas para COVID-19 se clasificaron según las siguientes categorías: a) contaminación por COVID-19, reportada en el 62,5% de los estudios; b) alta hospitalaria debido a mejoría, mencionada en el 37,5% de los artículos; c) fallecimiento, representando casos raros en el 25% de la muestra. La complicación gestacional más prevalente fue la prematuridad, mencionada en el 75% de los estudios. Esta complicación se observó debido a casos de rotura prematura de membranas y desprendimiento de placenta. Conclusiones: a pesar del conocimiento del comportamiento asintomático y levemente sintomático en los recién nacidos, es importante continuar la búsqueda de nuevos datos clínicos, ya que este público presenta reacciones inciertas a la infección por el SARS-CoV-2. Objetivos COVID19. COVID19 COVID 19. 19 Métodos PubMed Knowledge SCOPUS CINHAL 2111 2 111 2.11 final Resultados COVID-1 categorías COVID19, 19, 625 62 5 62,5 b mejoría 375 37 37,5 c fallecimiento 25 prematuridad 75 placenta Conclusiones SARSCoV2. SARSCoV2 SARSCoV SARS CoV 2. SARS-CoV-2 COVID1 1 211 11 2.1 COVID- 6 62, 3 37, 7 SARS-CoV- 21 SARS-CoV

https://doi.org/10.1590/0034-7167-2023-0400

Estratégias de enfrentamento na Atenção Primária à Saúde na pandemia de Covid-19 em Minas Gerais, Brasil
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Quites, Humberto Ferreira de Oliveira

; Silva, Tamires Carolina

; Viegas, Selma Maria da Fonseca

; Gontijo, Tarcisio Laerte

; Oliveira, Valéria Conceição de

; Guimarães, Eliete Albano de Azevedo

Saúde em Debate

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dec 2023, Volume 47 N. 139 Pages 818 - 829

Abstract: En Pt | Text: En Pt | PDF: En | PDF: Pt

ABSTRACT The aim was to analyze Primary Health Care (PHC) actions in response to the COVID-19 pandemic in municipalities in Minas Gerais. This is a quantitative, observational, and cross-sectional study. Data collection was carried out through the application of an online questionnaire, in which 278 municipal health secretaries from the state of Minas Gerais and/or coordinators of PHC took part. The health structure proved to be capable of providing the development of management functions based on data and information throughout the COVID-19 pandemic. Among the actions to face the population are the use of protocols, masks, use of physical barriers, penalty for crowding, and telephony resources to clarify doubts about COVID-19. As for the difficulties in controlling this disease by employees in the PHC, low professional remuneration, poor work organization, delay in test results, underreporting, lack of equipment and technological resources were mentioned. It is concluded that the numerous measures and tools adopted to control the COVID-19 pandemic were used by municipal authorities. However, despite technological resources, such as the e-SUS, providing epidemiological data on COVID-19, capable of assisting in the planning of health actions, these tools need to be improved.

RESUMO Objetivou-se analisar as ações da Atenção Primária à Saúde (APS) em resposta à pandemia de Covid-19 em municípios de Minas Gerais. Trata-se de um estudo quantitativo, observacional e transversal. A coleta de dados foi realizada mediante a aplicação de um questionário on-line, no qual participaram 278 secretários municipais de saúde do estado de Minas Gerais e/ou coordenadores da APS. A estrutura em saúde se demonstrou capaz de proporcionar o desenvolvimento de funções gerenciais com base em dados e informações ao longo da pandemia. Entre as ações de enfrentamento na população, estão o uso de protocolos, de máscaras, utilização de barreiras físicas, penalidade por aglomeração e recursos de telefonia para o esclarecimento de dúvidas sobre a Covid-19. Quanto às dificuldades de controle dessa doença pelos colaboradores na APS, foram citadas baixa remuneração profissional, precária organização do trabalho, demora dos resultados nos exames, subnotificação, falta de equipamentos e recursos tecnológicos. Conclui-se que inúmeras medidas e ferramentas adotadas para o controle da pandemia foram utilizadas pelas autoridades municipais. No entanto, apesar de os recursos tecnológicos, como o e-SUS, disponibilizarem dados epidemiológicos sobre a Covid-19, capazes de auxiliar no planejamento de ações em saúde, essas ferramentas necessitam de aperfeiçoamentos.

https://doi.org/10.1590/0103-1104202313907

Estratégias de enfrentamento na Atenção Primária à Saúde na pandemia de Covid-19 em Minas Gerais, Brasil Covid19 Covid 19 Covid-1 Gerais Covid1 1 Covid-
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Quites, Humberto Ferreira de Oliveira

; Silva, Tamires Carolina

; Viegas, Selma Maria da Fonseca

; Gontijo, Tarcisio Laerte

; Oliveira, Valéria Conceição de

; Guimarães, Eliete Albano de Azevedo

Saúde em Debate

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oct 2023, Volume 47 N. 139 Pages 818 - 829

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

https://doi.org/10.1590/0103-1104202313907

TNF-alpha and IL-17 cytokine levels in Brazilian patients with ankylosing spondylitis after anti-TNF therapy TNFalpha TNF alpha IL17 IL 17 IL-1 antiTNF anti IL1 1 IL-
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Lara-Armi, Fernanda Formaggi

; Visentainer, Jeane Eliete Laguila

; Braga, Matheus

; Zacarias, Joana Maira Valentini

; Rocha-Loures, Marco Antônio

; Neves, Janisleya Silva Ferreira

; Moliterno, Ricardo Alberto

; Sell, Ana Maria

Brazilian Journal of Pharmaceutical Sciences

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2023, Volume 59 elocation e22746

Abstract: En | Text: En | PDF: En

Abstract The aim of this study was to evaluate tumor necrosis factor alpha (TNF-α), interleukin (IL)- 17A/F levels in the serum of ankylosing spondylitis (AS) patients after anti-TNF therapy, in order to understand how these cytokines are involved in this therapeutic response. Forty-four AS patients were included in the study: thirty using anti-TNF therapy were classified according to their therapy response as responders (15) and non-responders (15) and 14 without anti-TNF therapy were classified as AS control. Fifteen healthy individuals formed the control group. Serum levels of TNF-α were determined using Luminex technology and for IL-17A and IL-17F using ELISA. The non-responder patients presented higher serum levels of TNF-α than the responders and AS control; the same results were found when HLA-B*27 positive or negative patients were separately analyzed. IL-17A and IL17F serum levels were similar for all groups. According to the clinical disease activity, AS patients with BASDAI ≥4 had higher serum levels of TNF-α than AS patients with BASDAI <4. Positive correlation was found between TNF-α levels and BASDAI. In AS patients, TNF-α serum levels were associated with anti-TNF therapy and disease activity independently of HLA-B*27, and IL-17A and IL-17F were not related to anti-TNF treatment. TNFα, TNFα TNF α , (TNF-α) IL (IL) 17AF AF 17A F A (AS antiTNF anti Fortyfour Forty four 15 (15 nonresponders non 1 group IL17A ILA ILF 17F ELISA nonresponder responder HLAB*27 HLAB27 HLAB HLA B*27 B 27 HLA-B*2 analyzed groups 4 ≥ <4 HLAB*27, B*27, treatment (TNF-α (IL (1 HLAB*2 HLAB2 B27 B*2 2 HLA-B* < ( HLAB* B2 B* HLA-B

https://doi.org/10.1590/s2175-97902023e22746

Rede de Atenção Psicossocial: desenvolvimento e validação de um instrumento multidimensional para avaliação da implantação (IMAI-RAPS) Psicossocial IMAIRAPS IMAI RAPS (IMAI-RAPS
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Coelho, Vivian Andrade Araujo

; Pauferro, Ana Luiza Moreira

; Silva, Mariana Arantes e

; Guimarães, Denise Alves

; Gama, Carlos Alberto Pegolo da

; Modena, Celina Maria

; Guimarães, Eliete Albano de Azevedo

Physis: Revista de Saúde Coletiva

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2023, Volume 33 elocation e33004

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Trata-se de um estudo metodológico para desenvolvimento e validação do Instrumento Multidimensional para Avaliação da Implantação da RAPS (IMAI-RAPS) em Minas Gerais (MG)/Brasil. O estudo foi executado em três etapas: estudo de avaliabilidade, desenvolvimento do IMAI-RAPS, aplicação da Técnica Delphi para validação de conteúdo e aparência das questões. Foram realizados a análise de documentos oficiais, revisão da literatura e um engajamento estruturado com membros do programa para esclarecer sua operacionalização e focalizar os aspectos centrais a serem avaliados. Um modelo teórico-lógico da RAPS foi construído de acordo com a tríade donabediana: estrutura, processo e resultado e organizado em: Unidades Mínimas (Assistência à Saúde Mental e Reabilitação Psicossocial), Conectividade (Articulação da Rede), Integração (Governança e Gestão do Cuidado), Normatividade (Política de Saúde Mental e Participação e Controle Social), Subjetividade e Estrutura (Serviços, Sistema Logístico e Educação em Saúde). Desse modelo derivou-se o IMAI-RAPS que foi validado por 44 experts da área indicando a abordagem de questões relevantes, úteis e viáveis para avaliação da estrutura e processo de implantação do programa em MG. A utilização da Técnica Delphi possibilitou que os produtos desenvolvidos fossem balizados por estudiosos ou profissionais da RAPS de diversas regiões do país aumentando o poder analítico da ferramenta. Tratase Trata se IMAIRAPS IMAI (IMAI-RAPS MG/Brasil. MGBrasil MG /Brasil. Brasil (MG)/Brasil etapas avaliabilidade IMAIRAPS, RAPS, oficiais avaliados teóricológico teórico lógico donabediana Assistência Psicossocial, Psicossocial , Psicossocial) Articulação Rede, Rede Rede) Governança Cuidado, Cuidado Cuidado) Política Social, Social Social) Serviços, Serviços (Serviços Saúde. . Saúde) derivouse derivou 4 relevantes ferramenta MG/Brasil /Brasil

Abstract This is a methodological study for the development and validation of the Multidimensional Instrument for Evaluating of the Implementation of Psychosocial Care Network (IMAI-RAPS) in Minas Gerais (MG)/Brazil. The study was carried out in three stages: evaluability study, development of the IMAIRAPS, application of the Delphi Technique for content and appearance validation of the questions. The analysis of official documents, literature review and a structured engagement with program members were carried out to clarify its operationalization and focus on the central aspects to be evaluated. A theoreticallogical model of RAPS was built according to the Donabedian triad: structure, process and result and organized into: Minimum Units (Mental Health Care and Psychosocial Rehabilitation), Connectivity (Network Articulation), Integration (Governance and Management of the Care), Normativity (Mental Health Policy and Participation and Social Control), Subjectivity and Structure (Services, Logistics System and Health Education). The IMAI-RAPS was derived from this model, which was validated by 44 experts in the field, indicating the approach of relevant, useful and viable questions for evaluating the structure and process of implementing the program in MG. The use of the Delphi Technique made it possible for the developed products to be marked out by Psychosocial Care Network scholars or professionals from different regions of the country, increasing the analytical power of the tool. IMAIRAPS IMAI (IMAI-RAPS MG/Brazil. MGBrazil MG /Brazil. Brazil (MG)/Brazil stages documents evaluated triad into Mental Rehabilitation, Rehabilitation , Rehabilitation) Articulation, Articulation Articulation) Governance Care, Care) Control, Control Control) Services, Services (Services Education. Education . Education) 4 field relevant country tool MG/Brazil /Brazil

https://doi.org/10.1590/s0103-7331202333004

Ghrelin and glucagon-like peptide-1 according to body adiposity and glucose homeostasis glucagonlike glucagon like peptide1 peptide 1 peptide-
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Lopes, Karynne Grutter

; Silva Junior, Vicente Lopes da

; Lopes, Fernanda de Azevedo Marques

; Bouskela, Eliete

; Souza, Maria das Graças Coelho de

; Kraemer-Aguiar, Luiz Guilherme

Archives of Endocrinology and Metabolism

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2023, Volume 67 N. 4 elocation e000611

Abstract: En | Text: En | PDF: En

ABSTRACT Objective: We investigated the biological behavior of ghrelin and glucagon-like peptide-1 (GLP-1) after a standard liquid meal according to body adiposity and glucose homeostasis. Subjects and methods: This cross-sectional study included 41 individuals (92.7% women; aged 38.3 ± 7.8 years; BMI 32.2 ± 5.5 kg/m²) allocated into three groups according to body adiposity and glucose homeostasis, as follows: normoglycemic eutrophic controls (CON, n = 11), normoglycemic with obesity (NOB, n = 15), and dysglycemic with obesity (DOB, n = 15). They were tested at fasting and 30 and 60 min after the ingestion of a standard liquid meal in which we measured active ghrelin, active GLP-1, insulin, and plasma glucose levels. Results: As expected, DOB exhibited the worst metabolic status (glucose, insulin, HOMA-IR, HbA1c) and an inflammatory status (TNF-α) at fasting, besides a more significant increase in glucose than postprandial NOB (p ≤ 0.05). At fasting, no differences between groups were detected in lipid profile, ghrelin, and GLP-1 (p ≥ 0.06). After the standard meal, all groups exhibited a reduction in ghrelin levels between fasting vs. 60 min (p ≤ 0.02). Additionally, we noticed that GLP-1 and insulin increased equally in all groups after the standard meal (fasting vs. 30 and 60 min). Although glucose levels increased in all groups after meal intake, these changes were significantly more significant in DOB vs. CON and NOB at 30 and 60 min post-meal (p ≤ 0.05). Conclusions: Time course of ghrelin and GLP-1 levels during the postprandial period was not influenced by body adiposity or glucose homeostasis. Similar behaviors occurred in controls and patients with obesity, independently of glucose homeostasis. Objective glucagonlike glucagon like peptide1 peptide 1 peptide- GLP1 GLP (GLP-1 homeostasis methods crosssectional cross sectional 4 92.7% 927 92 7 (92.7 women 383 38 3 38. 78 8 7. years 322 32 2 32. 55 5 5. kg/m² kgm² kgm kg m² m follows CON, (CON 11, 11 , 11) NOB, (NOB 15, 15 15) DOB, (DOB 15. . 6 GLP1, 1, Results expected glucose, (glucose HOMAIR, HOMAIR HOMA IR, IR HOMA-IR HbA1c HbAc HbA c TNFα TNF α (TNF-α p 0.05. 005 0.05 0 05 0.05) profile GLP- 0.06. 006 0.06 06 0.06) vs 0.02. 002 0.02 02 0.02) Additionally min. min) intake postmeal post Conclusions (GLP- 92.7 9 (92. kg/m 00 0.0 (GLP 92. (92 0. (9 (

https://doi.org/10.20945/2359-3997000000611

Rede de Atenção Psicossocial: desenvolvimento e validação de um instrumento multidimensional para avaliação da implantação (IMAI-RAPS)
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Coelho, Vivian Andrade Araujo

; Pauferro, Ana Luiza Moreira

; Silva, Mariana Arantes e

; Guimarães, Denise Alves

; Gama, Carlos Alberto Pegolo da

; Modena, Celina Maria

; Guimarães, Eliete Albano de Azevedo

Physis: Revista de Saúde Coletiva

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2023, Volume 33 elocation e33004

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

https://doi.org/10.1590/s0103-7331202333004

Prevalence and underreporting of immunization errors in childhood vaccination: results of a household survey vaccination
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Oliveira, Stênio Henrique

; Silva, Brener Santos

; Carvalho, Lívia Maria Rezende

; Gontijo, Tarcísio Laerte

; Pinto, Ione Carvalho

; Guimarães, Eliete Albano de Azevedo

; Oliveira, Valéria Conceição de

Revista da Escola de Enfermagem da USP

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2023, Volume 57 elocation e20230253

Abstract: Pt En Es | Text: Pt En Es | PDF: Pt | PDF: En | PDF: Es

RESUMO Objetivo: Investigar a subnotificação de erros de imunização a partir dos registros de vacinação da caderneta de crianças menores de cinco anos. Método: Estudo epidemiológico, transversal analítico, realizado por inquérito domiciliar com 453 crianças de 6 meses a 4 anos em três municípios de Minas Gerais em 2021. Realizaram-se a análise descritiva e o cálculo da prevalência do erro por 100 mil doses aplicadas entre 2016 e 2021. Estimou-se a magnitude da associação entre as variáveis pela prevalência e Intervalos de Confiança 95% (IC95%). Para a análise da subnotificação, utilizaram-se os registros de notificação do Estado. Resultados: Encontrou-se uma prevalência de erros de imunização de 41,9/100.000 doses aplicadas (IC95%:32,2 – 51,6). A maior prevalência ocorreu entre 2020 (50,0/100.000 doses aplicadas) e 2021 (78,6/100.000 doses aplicadas). O erro mais frequente foi intervalo inadequado entre vacinas (47,2%) associado à administração da vacina adsorvida difteria, tétano e pertussis (DTP) (13,7/100.000). O atraso vacinal relacionou-se ao erro de imunização (7,55 IC95%:2,30 – 24,80), e os erros encontrados foram subnotificados. Conclusão: A alta prevalência de erros subnotificados aponta para um cenário preocupante, ressaltando a importância de medidas preventivas. Objetivo Método epidemiológico analítico 45 Realizaramse Realizaram se 10 201 Estimouse Estimou 95 IC95%. IC95 IC IC95% . (IC95%) utilizaramse utilizaram Estado Resultados Encontrouse Encontrou 419100000 41 9 000 41,9/100.00 IC95%32,2 IC95322 32,2 32 2 (IC95%:32, 51,6. 516 51,6 51 51,6) 202 50,0/100.000 500100000 50 0 (50,0/100.00 78,6/100.000 786100000 78 (78,6/100.00 aplicadas. 47,2% 472 47 (47,2% difteria DTP (DTP 13,7/100.000. 137100000 13,7/100.000 13 7 (13,7/100.000) relacionouse relacionou 7,55 755 55 (7,5 IC95%2,30 IC95230 2,30 30 IC95%:2,3 24,80, 2480 24,80 , 24 80 24,80) Conclusão preocupante preventivas 1 20 IC9 (IC95% 41910000 00 41,9/100.0 IC95%32, IC9532 322 32, 3 (IC95%:32 51, 5 50,0/100.00 50010000 (50,0/100.0 78,6/100.00 78610000 (78,6/100.0 47,2 (47,2 13710000 13,7/100.00 (13,7/100.000 7,5 75 (7, IC95%2,3 IC9523 230 2,3 IC95%:2, 248 24,8 8 (IC95 4191000 41,9/100. IC95%32 IC953 (IC95%:3 50,0/100.0 5001000 (50,0/100. 78,6/100.0 7861000 (78,6/100. 47, (47, 1371000 13,7/100.0 (13,7/100.00 7, (7 IC95%2, IC952 23 2, IC95%:2 24, (IC9 419100 41,9/100 IC95%3 (IC95%: 50,0/100. 500100 (50,0/100 78,6/100. 786100 (78,6/100 (47 137100 13,7/100. (13,7/100.0 ( IC95%2 IC95%: (IC 41910 41,9/10 50,0/100 50010 (50,0/10 78,6/100 78610 (78,6/10 (4 13710 13,7/100 (13,7/100. 4191 41,9/1 50,0/10 5001 (50,0/1 78,6/10 7861 (78,6/1 1371 13,7/10 (13,7/100 419 41,9/ 50,0/1 500 (50,0/ 78,6/1 786 (78,6/ 137 13,7/1 (13,7/10 41,9 50,0/ (50,0 78,6/ (78,6 13,7/ (13,7/1 41, 50,0 (50, 78,6 (78, 13,7 (13,7/ 50, (50 78, (78 13, (13,7 (5 (13, (13 (1

ABSTRACT Objective: To investigate underreporting of immunization errors based on vaccination records from children under five years of age. Method: An epidemiological, cross-sectional analytical study, carried out through a household survey with 453 children aged 6 months to 4 years in three municipalities in Minas Gerais in 2021. A descriptive analysis was carried out, and the prevalence of the error was calculated per 100 thousand doses applied between 2016 and 2021. The magnitude was estimated of the association between variables by prevalence and 95% Confidence Intervals (95%CI). To analyze underreporting, State reporting records were used. Results: A prevalence of immunization errors was found to be 41.9/100,000 doses applied (95%CI:32.2 – 51.6). The highest prevalence occurred between 2020 (50.0/100,000 doses applied) and 2021 (78.6/100,000 doses applied). The most frequent error was an inadequate interval between vaccines (47.2%) associated with adsorbed diphtheria, tetanus and pertussis (DTP) vaccine (13.7/100,000) administration. Vaccination delay was related to immunization errors (7.55 95% CI:2.30 – 24.80), and the errors found were underreported. Conclusion: The high prevalence of underreported errors points to a worrying scenario, highlighting the importance of preventive measures. Objective age Method epidemiological crosssectional cross sectional study 45 10 201 95 95%CI. 95CI CI 95%CI . (95%CI) used Results 419100000 41 9 000 41.9/100,00 95%CI32.2 95CI322 32.2 32 2 (95%CI:32. 51.6. 516 51.6 51 51.6) 202 50.0/100,000 500100000 50 0 (50.0/100,00 78.6/100,000 786100000 78 (78.6/100,00 applied. 47.2% 472 47 (47.2% diphtheria DTP (DTP 13.7/100,000 137100000 13 7 (13.7/100,000 administration 7.55 755 55 (7.5 CI2.30 CI230 2.30 30 CI:2.3 24.80, 2480 24.80 , 24 80 24.80) Conclusion scenario measures 1 20 (95%CI 41910000 00 41.9/100,0 CI32 95%CI32. 95CI32 322 32. 3 (95%CI:32 51. 5 50.0/100,00 50010000 (50.0/100,0 78.6/100,00 78610000 (78.6/100,0 47.2 (47.2 13.7/100,00 13710000 (13.7/100,00 7.5 75 (7. CI2 CI2.3 CI23 230 2.3 CI:2. 248 24.8 8 4191000 41.9/100, CI3 95%CI32 95CI3 (95%CI:3 50.0/100,0 5001000 (50.0/100, 78.6/100,0 7861000 (78.6/100, 47. (47. 13.7/100,0 1371000 (13.7/100,0 7. (7 CI2. 23 2. CI:2 24. 419100 41.9/100 95%CI3 (95%CI: 50.0/100, 500100 (50.0/100 78.6/100, 786100 (78.6/100 (47 13.7/100, 137100 (13.7/100, ( CI: 41910 41.9/10 50.0/100 50010 (50.0/10 78.6/100 78610 (78.6/10 (4 13.7/100 13710 (13.7/100 4191 41.9/1 50.0/10 5001 (50.0/1 78.6/10 7861 (78.6/1 13.7/10 1371 (13.7/10 419 41.9/ 50.0/1 500 (50.0/ 78.6/1 786 (78.6/ 13.7/1 137 (13.7/1 41.9 50.0/ (50.0 78.6/ (78.6 13.7/ (13.7/ 41. 50.0 (50. 78.6 (78. 13.7 (13.7 50. (50 78. (78 13. (13. (5 (13 (1

RESUMEN Objetivo: Investigar el subregistro de errores de vacunación a partir de los registros de vacunación de niños menores de cinco años. Método: Estudio epidemiológico, analítico transversal, realizado mediante encuesta de hogares con 453 niños de 6 meses a 4 años en tres municipios de Minas Gerais en 2021. Análisis descriptivo y cálculo de la prevalencia de error por 100 mil dosis aplicadas entre 2016 y 2021. La magnitud de la asociación entre las variables se estimó mediante prevalencia e intervalos de confianza del 95% (IC95%). Para analizar el subregistro se utilizaron los registros de notificaciones estatales. Resultados: Se encontró una prevalencia de errores de inmunización de 41,9/100.000 dosis aplicadas (IC95%: 32,2 – 51,6). La prevalencia más alta se produjo entre 2020 (50,0/100.000 dosis aplicadas) y 2021 (78,6/100.000 dosis aplicadas). El error más frecuente fue un intervalo inadecuado entre vacunas (47,2%) asociado a la administración de la vacuna adsorbida contra la difteria, el tétanos y la tos ferina (DTP) (13,7/100.000). El retraso en la vacunación estuvo relacionado con errores de vacunación (7,55 IC 95%: 2,30 – 24,80), y los errores encontrados fueron subreportados. Conclusión: La alta prevalencia de errores no reportados apunta a un escenario preocupante, destacando la importancia de las medidas preventivas. Objetivo Método epidemiológico transversal 45 10 201 95 IC95%. IC95 IC95% . (IC95%) estatales Resultados 419100000 41 9 000 41,9/100.00 (IC95% 322 32 2 32, 51,6. 516 51,6 51 51,6) 202 50,0/100.000 500100000 50 0 (50,0/100.00 78,6/100.000 786100000 78 (78,6/100.00 aplicadas. 47,2% 472 47 (47,2% difteria DTP (DTP 13,7/100.000. 137100000 13,7/100.000 13 7 (13,7/100.000) 7,55 755 55 (7,5 230 30 2,3 24,80, 2480 24,80 , 24 80 24,80) subreportados Conclusión preocupante preventivas 1 20 IC9 41910000 00 41,9/100.0 (IC95 3 51, 5 50,0/100.00 50010000 (50,0/100.0 78,6/100.00 78610000 (78,6/100.0 47,2 (47,2 13710000 13,7/100.00 (13,7/100.000 7,5 75 (7, 23 2, 248 24,8 8 4191000 41,9/100. (IC9 50,0/100.0 5001000 (50,0/100. 78,6/100.0 7861000 (78,6/100. 47, (47, 1371000 13,7/100.0 (13,7/100.00 7, (7 24, 419100 41,9/100 (IC 50,0/100. 500100 (50,0/100 78,6/100. 786100 (78,6/100 (47 137100 13,7/100. (13,7/100.0 ( 41910 41,9/10 50,0/100 50010 (50,0/10 78,6/100 78610 (78,6/10 (4 13710 13,7/100 (13,7/100. 4191 41,9/1 50,0/10 5001 (50,0/1 78,6/10 7861 (78,6/1 1371 13,7/10 (13,7/100 419 41,9/ 50,0/1 500 (50,0/ 78,6/1 786 (78,6/ 137 13,7/1 (13,7/10 41,9 50,0/ (50,0 78,6/ (78,6 13,7/ (13,7/1 41, 50,0 (50, 78,6 (78, 13,7 (13,7/ 50, (50 78, (78 13, (13,7 (5 (13, (13 (1

https://doi.org/10.1590/1980-220x-reeusp-2023-0253en

10.

Disparidade de Gênero na Autoria Principal e Sênior em Periódicos Brasileiros de Cardiologia
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Mesquita, Claudio Tinoco

; Lacerda, Aline Goneli de

; Urel, Isabella Carolina de Almeida Barros

; Frantz, Eliete Dalla Corte

; Alves, Vinícius de Pádua Vieira

; Amorim, Luana Evelyn de Oliveira

; Coutinho, Bruna de Almeida

; Dalben, Letícia Rodrigues

; Abrantes, Juliana Cadilho da Silva

; Veloso, Vanessa Dias

; Mello, Luíza Lucchesi Cabral de

; Oliveira, Gláucia Maria Moraes de

; Fernandes, Fernando de Amorim

Arquivos Brasileiros de Cardiologia

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dec 2022, Volume 119 N. 6 Pages 960 - 967

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Fundamento: Apesar da importância das mulheres na pesquisa clínica, não existe uma avaliação da fração de mulheres em posições de autoria nos periódicos de cardiologia da SBC. Objetivos: Avaliar a fração de mulheres autoras na International Journal of Cardiovascular Sciences (IJCS) e nos Arquivos Brasileiros de Cardiologia (ABC Cardiol) nas últimas décadas. Métodos: Realizamos busca dos artigos originais dos ABC Cardiol, entre 2000 e 2019, e da IJCS, entre 2010 e 2019. Foi feito levantamento do número de primeiras e últimas autoras e do total de artigos originais de 2010 a 2019. Calculamos as proporções totais de autorias femininas e comparamos o primeiro quinquênio com o segundo. Para avaliar a evolução temporal das duas décadas, analisamos apenas dados dos ABC Cardiol. Utilizamos o teste Qui-quadrado para analisar as diferenças dentro de cada revista e entre ambas. O software IBM® SPSS® foi utilizado nas análises. O nível de significância adotado foi de 5%. Resultados: De 2010 a 2019, foram publicados 1157 artigos originais nos ABC Cardiol e 398 na IJCS. Observamos que as mulheres têm maior predominância como primeiras autoras na IJCS em relação aos ABC Cardiol, mas os homens predominam como últimos autores em ambos. De 2010 a 2019, não houve modificação significativa na proporção de autorias femininas. Ao longo das décadas analisadas para os ABC Cardiol, houve projeção de crescimento linear de autorias femininas, sendo que a inclinação da reta é maior na projeção da primeira autoria que na autoria sênior. Conclusões: Há disparidade de gênero com menor representatividade feminina nas autorias dos artigos dos periódicos cardiológicos brasileiros analisados: Arquivos Brasileiros de Cardiologia e International Journal of Cardiovascular Sciences. Acreditamos que a partir destes resultados mais esforços devam ser implementados em busca de equidade de gênero na produção científica cardiológica veiculada por estes periódicos.

Abstract Background: Despite the importance of women in clinical research, no assessment has been made of the fraction of women in a leadership positions in the Cardiology journals of the SBC. Objectives: To assess the fraction of female authors in the International Journal of Cardiovascular Sciences (IJCS) and the Arquivos Brasileiros de Cardiologia (ABC Cardiol) over the last decades. Methods: We searched the original articles of the ABC Cardiol, from 2000 to 2019, and of the IJCS, from 2010 to 2019. We surveyed the number of first and senior female authors and the total number of original articles from 2010 to 2019. We calculated the total proportion of female authorship and compared the first quinquennium with the second. Only data from the ABC Cardiol were analyzed to assess the temporal evolution of the two decades. We used the chi-square test to assess the differences within each journal and between them. The IBM® SPSS® software was used in the analyses. The level of significance adopted was 5%. Results: From 2010 to 2019, 1,157 original articles were published in the ABC Cardiol and 398 in the IJCS. We observed that women are more prevalent as first authors in the IJCS compared to the ABC Cardiol, but men prevail as senior authors in both journals. From 2010 to 2019, there was no significant change in the proportion of female authorship. Throughout the decades analyzed for the ABC Cardiol, there was a projection of linear growth of female authorship, with the slope of the line being greater in the first authorship than in senior authorship. Conclusions: There is gender disparity, with lower female representativeness in authorship in the articles from the Brazilian Cardiology journals analyzed: Arquivos Brasileiros de Cardiologia and International Journal of Cardiovascular Sciences. We believe that based on these results, more efforts should be implemented in the search for gender equity in the cardiology scientific production published by these journals.

https://doi.org/10.36660/abc.20220058

11.

Cerveja egípcia? Educação para as relações étnico-raciais (ERER) na formação docente em Química
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Silva, Eliete Lucia

; Camargo, Marysson Jonas Rodrigues

; Benite, Anna Maria Canavarro

Química Nova

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2022, Volume 45 N. 2 Pages 235 - 244

Abstract: Pt | Text: Pt | PDF: Pt

EGYPTIAN BEER? EDUCATION FOR ETHNIC-RACIAL RELATIONS (ERER) IN TEACHER FORMATION IN CHEMISTRY. This work was carried out in a Higher Education Institution (IES), in the State of Goiás, in the Chemistry Degree course, aiming at the implementation of Law 10639/03. The context discussed herein is the chemical knowledge of African and diasporic matrices from Ancient Egypt in the development and production of beer. In order to subsidize teachers in initial formation with strategies in the classroom for an anti-racist education, taking into account the contribution of African people in the constitution of the country. It is an action research and its development happened through a Pedagogical Intervention (IP) with the theme: Ancient Egypt, Beer and Chemistry. The results were collected through audio recording and analyzed using the Conversation Analysis technique. Our results have shown that it is possible to talk about African history and culture, in a chemistry class in the initial chemistry teacher training course, making an epistemic shift in the curriculum, taking previously silenced knowledge to school, such as the history and culture of African peoples.

https://doi.org/10.21577/0100-4042.20170833

12.

Diretrizes Brasileiras de Hipertensão Arterial – 2020
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Barroso, Weimar Kunz Sebba

; Rodrigues, Cibele Isaac Saad

; Bortolotto, Luiz Aparecido

; Mota-Gomes, Marco Antônio

; Brandão, Andréa Araujo

; Feitosa, Audes Diógenes de Magalhães

; Machado, Carlos Alberto

; Poli-de-Figueiredo, Carlos Eduardo

; Amodeo, Celso

; Mion Júnior, Décio

; Barbosa, Eduardo Costa Duarte

; Nobre, Fernando

; Guimarães, Isabel Cristina Britto

; Vilela-Martin, José Fernando

; Yugar-Toledo, Juan Carlos

; Magalhães, Maria Eliane Campos

; Neves, Mário Fritsch Toros

; Jardim, Paulo César Brandão Veiga

; Miranda, Roberto Dischinger

; Póvoa, Rui Manuel dos Santos

; Fuchs, Sandra C

; Alessi, Alexandre

; Lucena, Alexandre Jorge Gomes de

; Avezum, Alvaro

; Sousa, Ana Luiza Lima

; Pio-Abreu, Andrea

; Sposito, Andrei Carvalho

; Pierin, Angela Maria Geraldo

; Paiva, Annelise Machado Gomes de

; Spinelli, Antonio Carlos de Souza

; Nogueira, Armando da Rocha

; Dinamarco, Nelson

; Eibel, Bruna

; Forjaz, Cláudia Lúcia de Moraes

; Zanini, Claudia Regina de Oliveira

; Souza, Cristiane Bueno de

; Souza, Dilma do Socorro Moraes de

; Nilson, Eduardo Augusto Fernandes

; Costa, Elisa Franco de Assis

; Freitas, Elizabete Viana de

; Duarte, Elizabeth da Rosa

; Muxfeldt, Elizabeth Silaid

; Lima Júnior, Emilton

; Campana, Erika Maria Gonçalves

; Cesarino, Evandro José

; Marques, Fabiana

; Argenta, Fábio

; Consolim-Colombo, Fernanda Marciano

; Baptista, Fernanda Spadotto

; Almeida, Fernando Antonio de

; Borelli, Flávio Antonio de Oliveira

; Fuchs, Flávio Danni

; Plavnik, Frida Liane

; Salles, Gil Fernando

; Feitosa, Gilson Soares

; Silva, Giovanio Vieira da

; Guerra, Grazia Maria

; Moreno Júnior, Heitor

; Finimundi, Helius Carlos

; Back, Isabela de Carlos

; Oliveira Filho, João Bosco de

; Gemelli, João Roberto

; Mill, José Geraldo

; Ribeiro, José Marcio

; Lotaif, Leda A. Daud

; Costa, Lilian Soares da

; Magalhães, Lucélia Batista Neves Cunha

; Drager, Luciano Ferreira

; Martin, Luis Cuadrado

; Scala, Luiz César Nazário

; Almeida, Madson Q.

; Gowdak, Marcia Maria Godoy

; Klein, Marcia Regina Simas Torres

; Malachias, Marcus Vinícius Bolívar

; Kuschnir, Maria Cristina Caetano

; Pinheiro, Maria Eliete

; Borba, Mario Henrique Elesbão de

; Moreira Filho, Osni

; Passarelli Júnior, Oswaldo

; Coelho, Otavio Rizzi

; Vitorino, Priscila Valverde de Oliveira

; Ribeiro Junior, Renault Mattos

; Esporcatte, Roberto

; Franco, Roberto

; Pedrosa, Rodrigo

; Mulinari, Rogerio Andrade

; Paula, Rogério Baumgratz de

; Okawa, Rogério Toshiro Passos

; Rosa, Ronaldo Fernandes

; Amaral, Sandra Lia do

; Ferreira-Filho, Sebastião R.

; Kaiser, Sergio Emanuel

; Jardim, Thiago de Souza Veiga

; Guimarães, Vanildo

; Koch, Vera H.

; Oigman, Wille

; Nadruz, Wilson

Arquivos Brasileiros de Cardiologia

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mar 2021, Volume 116 N. 3 Pages 516 - 658

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

https://doi.org/10.36660/abc.20201238 10948 downloads

13.

Analysis of scientific production on the new coronavirus (COVID-19): a bibliometric analysis
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Oliveira, Erika Morganna Neves de

; Carvalho, Ana Raquel Batista de

; Silva, Joyce Soares e

; Sousa Neto, Antônio Rosa de

; Moura, Maria Eliete Batista

; Freitas, Daniela Reis Joaquim de

Sao Paulo Medical Journal

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feb 2021, Volume 139 N. 1 Pages 3 - 9

Abstract: En | Text: En | PDF: En

ABSTRACT BACKGROUND: The pandemic of the new coronavirus has culminated in a scientific race to seek knowledge about this virus and its treatments, vaccines and preventive strategies, in order to reduce its impact on healthcare and economics worldwide. Hence, it is important to recognize the efforts of researchers who are at the forefront of investigations relating to the new coronavirus. OBJECTIVE: The present study was carried out with the aim of analyzing the world scientific production relating to COVID-19. DESIGN AND SETTING: Exploratory and descriptive bibliometric study conducted in the city of Teresina (PI), Brazil. METHOD: ISI Web of Knowledge/Web of Science (WOS) was chosen as the database. Data-gathering was carried out in May 2020. The data analysis was performed using the HistCiteTM software, version 9.8.24, and the VOSviewer bibliometric analysis software, version 1.6.8. RESULTS: 2,625 published papers that included descriptors within the scope of this investigation were identified. These articles were published in 859 different journals that are indexed in WOS, by 9,791 authors who were linked to 3,365 research institutions, located in 105 countries. CONCLUSION: Ascertaining scientific production through a bibliometric analysis is important in order to guide researchers on what has already been produced and what is being researched, so as to be able to address gaps in knowledge through future research.

https://doi.org/10.1590/1516-3180.2020.0449.r1.01102020 733 downloads

14.

Gender debate as a challenge in nursing training
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Nogueira, Isabela Cristina

; Santos, Debora de Souza

; Sanfelice, Clara Fróes de Oliveira

; Silva, Eliete Maria

; Assis, Ana Elisa Spaolonzi Queiroz

Revista Brasileira de Enfermagem

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2021, Volume 74 N. 5 elocation e20201001

Abstract: Pt En Es | Text: Pt En Es | PDF: Pt | PDF: En | PDF: Es

RESUMO Objetivos: compreender os desafios da inserção do debate de gênero no processo formativo de enfermeiras(os) na perspectiva de estudantes de graduação. Métodos: estudo qualitativo, exploratório-explicativo. Os dados foram coletados por entrevista semiestruturada aplicada a 12 graduandas(os) de enfermagem de universidade pública paulista. Para tratamento e análise dos dados, utilizou-se o método do Discurso do Sujeito Coletivo à luz do referencial teórico do paradigma de produção de conhecimento de Boaventura de Sousa Santos. Resultados: a formação em enfermagem continua centrada no modelo científico tradicional, negligenciando o gênero e fortalecendo estereótipos voltados à feminilização da profissão. Considerações Finais: a formação das(os) enfermeiras(os) tem o desafio de implementar ações que aprofundem o tema gênero. Para tanto, sugerem-se algumas estratégias, como o aperfeiçoamento da formação docente e apropriação de práticas pedagógicas emancipatórias; a revisão dos projetos políticos pedagógicos; a teorização e reestruturação curricular; a problematização das questões de gênero para liderança de enfermagem.

ABSTRACT Objectives: to understand the challenges of introducing gender debate in nursing training from undergraduate students’ perspective. Methods: a qualitative, exploratory-explanatory study. Data were collected through a semi-structured interview applied to 12 undergraduate nursing students at a public university in São Paulo. For data treatment and analysis, the Discourse of the Collective Subject was used in light of Boaventura de Sousa Santos’ knowledge production paradigm theoretical framework. Results: nursing education remains centered on the traditional scientific model, neglecting gender and strengthening stereotypes aimed at the feminization of the profession. Final Considerations: nursing training has a challenge of implementing actions that deepen the gender theme. Therefore, some strategies are suggested, such as improving professor training and appropriating emancipatory pedagogical practices; reviewing pedagogical political projects; curriculum theorization and restructuring; problematizing gender issues for nursing leadership.

RESUMEN Objetivos: comprender los desafíos de insertar el debate de género en el proceso de formación de enfermeras desde la perspectiva de los estudiantes de pregrado. Métodos: estudio cualitativo, exploratorio-explicativo. Los datos fueron recolectados mediante entrevistas semiestructuradas aplicadas a 12 estudiantes de enfermería de una universidad pública de São Paulo. Para el tratamiento y análisis de los datos se utilizó el método del Discurso Colectivo del Sujeto a la luz del marco teórico del paradigma de producción de conocimiento de Boaventura de Sousa Santos. Resultados: la formación en enfermería sigue centrada en el modelo científico tradicional, descuidando el género y fortaleciendo los estereotipos orientados a la feminización de la profesión. Consideraciones Finales: la formación de enfermeras tiene el desafío de implementar acciones que profundicen el tema de género. Para ello, se sugieren algunas estrategias, como mejorar la formación del profesorado y apropiarse de prácticas pedagógicas emancipadoras; la revisión de proyectos políticos pedagógicos; teorización y reestructuración curricular; la problematización de las cuestiones de género para el liderazgo de enfermería.

https://doi.org/10.1590/0034-7167-2020-1001 181 downloads

15.

COVID-19: The question of genetic diversity and therapeutic intervention approaches
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Figueiredo, David Livingstone Alves

; Ximenez, João Paulo Bianchi

; Seiva, Fábio Rodrigues Ferreira

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Genetics and Molecular Biology

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2021, Volume 44 N. 1 elocation e20200452

Abstract: En | Text: En | PDF: En

Abstract Coronavirus disease 2019 (COVID-19), caused by the Severe Acute Respiratory Syndrome Coronavirus type 2 (SARS-CoV-2), is the largest pandemic in modern history with very high infection rates and considerable mortality. The disease, which emerged in China’s Wuhan province, had its first reported case on December 29, 2019, and spread rapidly worldwide. On March 11, 2020, the World Health Organization (WHO) declared the COVID-19 outbreak a pandemic and global health emergency. Since the outbreak, efforts to develop COVID-19 vaccines, engineer new drugs, and evaluate existing ones for drug repurposing have been intensively undertaken to find ways to control this pandemic. COVID-19 therapeutic strategies aim to impair molecular pathways involved in the virus entrance and replication or interfere in the patients’ overreaction and immunopathology. Moreover, nanotechnology could be an approach to boost the activity of new drugs. Several COVID-19 vaccine candidates have received emergency-use or full authorization in one or more countries, and others are being developed and tested. This review assesses the different strategies currently proposed to control COVID-19 and the issues or limitations imposed on some approaches by the human and viral genetic variability.

https://doi.org/10.1590/1678-4685-gmb-2020-0452

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