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1.
Conidiobolomycosis with neurological commitment in sheep in Pará, Brazil Pará
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Barbosa, Camila Cordeiro
; Filho, Carlos Eduardo da Silva Ferreira
; Silveira, Natália da Silva e Silva
; Oliveira, Carlos Magno Chaves
; Ferreira, Tatiane Teles Albernaz
; Silveira, José Alcides Sarmento da
; Duarte, Marcos Dutra
; Costa, Paulo Sérgio Chagas da
; Pereira, Gabriela Oliveira
; Brito, Marilene de Farias
; Barbosa, José Diomedes
.
RESUMO: O estudo foi realizado em um ovino, fêmea, de três anos de idade, da raça santa inês, procedente de uma propriedade localizada do município de Santo Antônio de Tauá, oeste do Pará. O animal acometido tinha histórico de exoftalmia no olho esquerdo, secreção nasal e dificuldade respiratória há mais de três meses. Ao exame físico o animal apresentava baixo escore corporal, apatia, assimetria facial unilateral, moderada exoftalmia unilateral esquerda, dispneia mista e exsudação nasal serossanguinolenta profusa unilateral. À necropsia, foi observada grande massa nasal, predominantemente branco-amarelada com áreas vermelho enegrecidas, de superfície irregular, finamente granular, úmida e friável. A massa invadia desde a junção mucocutânea do nariz esquerdo até as coanas, se infiltrava pelos seios nasais frontais, placa cribiforme e alcançava as meninges e a porção frontal do cérebro. À microscopia da superfície do epitélio nasal notou-se severa destruição dos cornetos e dos epitélios, evidenciada por extensas áreas de necrose com muitos debris celulares, ulceração e infecção bacteriana secundária. No sistema nervoso central (SNC) havia meningite piogranulomatosa com acentuada congestão de vasos, focos de necrose e inflamação granulomatosa. O diagnóstico de rinite granulomatosa de origem micótica associada ao fungo Conidiobolus lamprauges foi baseado nos achados da imuno-histoquímica. RESUMO ovino fêmea idade inês Tauá Pará meses corporal apatia esquerda necropsia brancoamarelada branco amarelada enegrecidas irregular granular friável coanas frontais cérebro notouse notou epitélios celulares secundária SNC (SNC vasos imunohistoquímica. imunohistoquímica imuno histoquímica. histoquímica imuno-histoquímica
ABSTRACT: The study was conducted on a 3-year-old female Santa Inês sheep from a property located in the municipality of Santo Antônio de Tauá, west of Pará. The affected animal had a history of exophthalmos in the left eye, nasal discharge, and breathing difficulty for more than three months. On physical examination, the animal had a low body score, apathy, unilateral facial asymmetry, moderate unilateral left exophthalmos, mixed dyspnea and unilateral profuse serosanguinous nasal discharge. At necropsy, a large nasal mass was observed, predominantly yellowish-white with blackish-red areas, with an irregular, finely granular, moist, and friable surface. The mass invaded from the mucocutaneous junction of the left nostril to the choanae, infiltrated the frontal sinuses, the cribiform plate, and reached the meninges and the frontal portion of the brain. Microscopy of the surface of the nasal epithelium showed severe destruction of the turbinates and epithelia, evidenced by extensive areas of necrosis with a large amount of cellular debris, ulceration, and secondary bacterial infection. In the central nervous system there was pyogranulomatous meningitis with marked vessel congestion, as well as foci of necrosis and granulomatous inflammation. Immunohistochemistry showed intense staining of numerous intralesional hyphae for antibodies against Conidiobolus lamprauges. The diagnosis of granulomatous rhinitis of mycotic origin associated with the Conidiobolus lamprauges was based on epidemiological, clinical-pathological, and immunohistochemical data. ABSTRACT 3yearold yearold 3 year old Tauá Pará eye discharge months examination score apathy asymmetry necropsy observed yellowishwhite yellowish white blackishred blackish red irregular granular moist choanae sinuses plate brain epithelia debris ulceration infection congestion inflammation epidemiological clinicalpathological, clinicalpathological clinical pathological, pathological clinical-pathological data
2.
Herbicide selectivity for conventional maize hybrid
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Rosa, Victória C. S.
; Braz, Guilherme B. P.
; Souza, Matheus de F.
; Procópio, Sergio de O.
; Ferreira, Camila J. B.
; Silva, Alessandro G. da
; Carmo, Eduardo L. do
.
RESUMO O cultivo do milho convencional em áreas de refúgio é importante para preservação da tecnologia Bt e para atender mercados específicos com maior valor agregado aos grãos. Portanto, as pesquisas voltadas ao controle químico de plantas daninhas também devem continuar direcionadas aos híbridos convencionais de milho. O objetivo foi avaliar a seletividade de herbicidas aplicados em pré e pós-emergência de um híbrido convencional de milho cultivado no bioma Cerrado do Brasil. Foram instalados dois experimentos de campo, um na safra verão e outro segunda safra. Os tratamentos foram onze herbicidas, cujas doses são apresentadas em g ha-1 de ingrediente ativo: S-metolachlor (1.680), mesotrione + atrazine (115,2 + 2.000), mesotrione + atrazine (192 + 2.000), tembotrione + atrazine (75,6 + 2.000), tembotrione + atrazine (100,8 + 2.000), nicosulfuron + atrazine (16 + 2.000), nicosulfuron + atrazine (24 + 2.000), [mesotrione + atrazine] ([120 + 1.,200]), aplicação sequencial de [mesotrione + atrazine] ([60 + 600]), atrazine (2.000), mais testemunha capinada. Independentemente do experimento, todos os herbicidas aplicados pré e pós-emergência do milho proporcionaram baixos percentuais de fitointoxicação. Em ambos os experimentos nenhum dos tratamentos causou redução no estande, confirmando a ausência de mortalidade das plantas pela aplicação de herbicidas. O tombamento/acamamento das plantas foi observado no experimento realizado de verão e não observou efeito entre tratamentos. Massa de 100 grãos e produtividade do milho não alteraram em função da aplicação de herbicidas na pré e pósemergência da cultura. Todos os tratamentos herbicidas avaliados apresentaram seletividade ao híbrido de milho convencional. Portanto pós emergência Brasil campo ha1 ha 1 ha- ativo Smetolachlor S metolachlor 1.680, 1680 1.680 , 680 (1.680) 115,2 1152 115 2 (115, 2.000, 2000 2.000 000 2.000) 192 (19 75,6 756 75 6 (75, 100,8 1008 8 (100, 16 (1 24 (2 120 ([12 1.,200, 1200 1.,200 200 1.,200]) 60 ([6 600, 600 600]) (2.000) capinada fitointoxicação estande tombamentoacamamento tombamento acamamento 10 cultura 168 1.68 68 (1.680 115, 11 (115 2.00 00 19 75, 7 (75 100, (100 ( 12 ([1 1.,20 20 1.,200] ([ 600] (2.000 1.6 (1.68 (11 2.0 0 (7 (10 1.,2 (2.00 1. (1.6 2. 1., (2.0 (1. (2.
ABSTRACT The cultivation of conventional maize in refuge areas is important for preserving Bt technology and serving specific markets with greater added value to the grains. Therefore, research aimed at chemical weed control must also continue to be directed to conventional maize hybrids. The objective was to evaluate the selectivity of herbicides applied in preand post-emergence of a conventional maize hybrid cultivated in the Cerrado biome of Brazil. Two field experiments were set up, one in summer and the other in second season. The treatments were composed of eleven herbicide treatments, whose doses are presented in g ha-1 of active ingredient: S-metolachlor (1,440), S-metolachlor (1,680), mesotrione + atrazine (115.2 + 2,000), mesotrione + atrazine (192 + 2,000), tembotrione + atrazine (75.6 + 2,000), tembotrione + atrazine (100.8 + 2,000), nicosulfuron + atrazine (16 + 2,000), nicosulfuron + atrazine (24 + 2,000), [mesotrione + atrazine] ([120 + 1,200]), sequential application of [mesotrione + atrazine] ([60 + 600]), atrazine (2,000), plus a weeded control. Regardless of the experiment, all herbicides applied preand post-emergence of maize led to low percentages of phytointoxication. In both experiments, none of the treatments caused reductions in crop stand, confirming the absence of plant mortality due to the application of herbicides. Plant tipping/lodging was seen in summer maize, with no treatment effect. Maize 100grain mass and yield did not change as a result of the application of herbicides in preand post-emergence of the crop. All herbicide treatments evaluated showed selectivity for the conventional maize hybrid. grains Therefore hybrids postemergence post emergence Brazil up season ha1 ha 1 ha- ingredient Smetolachlor S metolachlor 1,440, 1440 1,440 , 440 (1,440) 1,680, 1680 1,680 680 (1,680) 115.2 1152 115 2 (115. 2,000, 2000 2,000 000 2,000) 192 (19 75.6 756 75 6 (75. 100.8 1008 100 8 (100. 16 (1 24 (2 120 ([12 1,200, 1200 1,200 200 1,200]) 60 ([6 600, 600 600]) (2,000) experiment phytointoxication stand tippinglodging tipping lodging effect grain 144 1,44 44 (1,440 168 1,68 68 (1,680 115. 11 (115 2,00 00 19 75. 7 (75 100. 10 (100 ( 12 ([1 1,20 20 1,200] ([ 600] (2,000 14 1,4 4 (1,44 1,6 (1,68 (11 2,0 0 (7 (10 1,2 (2,00 1, (1,4 (1,6 2, (2,0 (1, (2,
3.
Response to Cetuximab in Squamous Cell Carcinoma of the Anal Canal After Multiple Lines of Chemotherapy and Immunotherapy
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Segovia, Javier Mauricio
; Osorio, Sergio
; Cantor, Erick Andrés
; Pino, Luis Eduardo
; Vargas, Henry Alexánder
; Murillo-Silva, John Alejandro
; Triana, Iván Camilo
; Navas-Cardona, Valentina
.
Abstract Primary anal cancer accounts for 1% to 3% of gastrointestinal cancers. The most common histology is squamous cell carcinoma, with an incidence of 0.5 to 2 per 100,000 people. The main risk factor is infection with the human papillomavirus, particularly subtypes 16 and 18, which represent 85% to 93% of cases. Treatment and prognosis depend on the stage of the tumor. Localized tumors can be treated with curative surgery, but locally advanced stages require a combination of chemotherapy and radiation. Advanced-stage tumors (IIIC and IV) have a poor prognosis even with chemotherapy. In recent years, immunotherapy and targeted therapies have shown promise in improving survival for patients with advanced, recurrent, or difficult-to-treat disease. We present the case of a 69-year-old woman with moderately differentiated squamous cell carcinoma (T2N1M0, stage IIIA) of the anal canal who, after treatment with chemoradiotherapy and checkpoint inhibitors and subsequent disease progression, received targeted therapy (cetuximab) and achieved complete remission with a sustained response for over 18 months. This case highlights the challenges of treating advanced anal cancer and the potential benefits of targeted therapy, particularly cetuximab, in achieving long-term responses. Further research and large-scale studies are needed to determine the role of targeted therapy and immunotherapy in the treatment of anal canal cancer.
Resumen El cáncer anal primario representa del 1% al 3% de los cánceres gastrointestinales. La histología más común es el carcinoma escamocelular, con una incidencia de 0,5 a 2 por cada 100.000 personas. El principal factor de riesgo es la infección por el virus del papiloma humano, especialmente los subtipos 16 y 18, que representan del 85% al 93% de los casos. El tratamiento y el pronóstico dependen del estadio del tumor. Los tumores localizados se pueden tratar con cirugía curativa, pero las etapas localmente avanzadas requieren una combinación de quimioterapia y radiación. Los tumores en estadio avanzado (IIIC y IV) tienen un mal pronóstico incluso con quimioterapia. En los últimos años, la inmunoterapia y las terapias dirigidas son prometedoras para mejorar la supervivencia de los pacientes con enfermedad avanzada, recurrente o difícil de tratar. Se presenta el caso de una mujer de 69 años con carcinoma escamocelular moderadamente diferenciado (T2N1M0, estadio IIIA) del canal anal que, después del tratamiento con quimiorradioterapia e inhibidores de punto de chequeo y luego de la progresión de la enfermedad, recibió tratamiento con terapia blanco (cetuximab) y logró la remisión completa de la enfermedad y una respuesta mantenida por más de 18 meses. Este caso destaca los desafíos del tratamiento del cáncer anal avanzado y los beneficios potenciales de la terapia dirigida, especialmente cetuximab, para lograr respuestas a largo plazo. Se necesitan más investigaciones y estudios a gran escala para determinar el papel de la terapia blanco y la inmunoterapia en el tratamiento del cáncer del canal anal.
4.
Hospital cohort study on survival predictors for intubated coronavirus disease 2019 patients 201 20 2
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Deschamps, Fabiola Jahn
; Deschamps, Paulo Sergio da Silva
; Silva, Laura Correa da
; Blos, Ellen Karkow
; Savoldi, Eduardo Schmidt
; Garcia, Maria Julia Coelho
; Staub, Guilherme Jönck
; Rocha, Franciani Rodrigues da
; Laporta, Gabriel Zorello
.
SUMMARY OBJECTIVE: The objective of this study was to assess the predictors of survival among patients with coronavirus disease 2019 who underwent tracheal intubation, as part of a hospital cohort study. METHODS: This retrospective cohort study in the Rio do Sul County Hospital, Santa Catarina, Brazil, from April 2020 to May 2021, focused on patients aged 18 years or older intubated for coronavirus disease 2019. We assessed the 90-day survival of intubated patients by estimating the hazard ratio using a Cox proportional hazards regression model. RESULTS: The study included 132 participants, with an average age of approximately 60 years. Tracheal intubation was successfully accomplished in 97% of cases within two attempts. The overall mortality rate was 62.9%. Notably, mortality rates were significantly higher in patients aged over 60 years (hazard ratio=2.57; 95%CI 1.54–4.29; p<0.001), those with blood oxygen saturation below 85% (hazard ratio=1.92; 95%CI 1.03–3.57; p=0.04), instances where tracheal intubation was carried out using a conventional laryngoscope (hazard ratio=2.59; 95%CI 1.22–5.48; p=0.013), and when performed by emergency physicians (hazard ratio=3.96; 95%CI 1.51–10.4; p=0.005). CONCLUSION: Our analysis unveiled that the risk of death in intubated coronavirus disease 2019 patients is four times higher when an emergency physician, as opposed to an anesthesiologist, leads the tracheal intubation team. OBJECTIVE 201 METHODS Hospital Catarina Brazil 202 2021 1 90day day 90 model RESULTS 13 participants 6 97 attempts 629 62 9 62.9% Notably ratio=2.57 ratio257 2 57 95CI CI 95 1.54–4.29 154429 54 4 29 p<0.001, p0001 p p<0.001 , 0 001 p<0.001) 85 ratio=1.92 ratio192 92 1.03–3.57 103357 03 3 p=0.04, p004 p=0.04 04 p=0.04) ratio=2.59 ratio259 59 1.22–5.48 122548 22 5 48 p=0.013, p0013 p=0.013 013 p=0.013) ratio=3.96 ratio396 96 1.51–10.4 151104 51 10 p=0.005. p0005 p=0.005 . 005 p=0.005) CONCLUSION physician anesthesiologist team 20 62.9 ratio=2.5 ratio25 1.54–4.2 15442 p000 p<0.00 00 8 ratio=1.9 ratio19 1.03–3.5 10335 p00 p=0.0 1.22–5.4 12254 p001 p=0.01 01 ratio=3.9 ratio39 1.51–10. 15110 p=0.00 62. ratio=2. ratio2 1.54–4. 1544 p<0.0 ratio=1. ratio1 1.03–3. 1033 p0 p=0. 1.22–5. 1225 ratio=3. ratio3 1.51–10 1511 ratio=2 1.54–4 154 p<0. ratio=1 1.03–3 103 p=0 1.22–5 122 ratio=3 1.51–1 151 ratio= 1.54– 15 p<0 1.03– p= 1.22– 12 1.51– 1.54 p< 1.03 1.22 1.51 1.5 1.0 1.2 1.
5.
The path to elimination: FEBRASGO 2023's targeted strategies against cervical cancer in Brazil elimination 2023s s 2023 202 20 2
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da Silva Filho, Agnaldo Lopes
; Roteli-Martins, Cecilia Maria
; de Góis Speck, Neila Maria
; de Carvalho, Newton Sérgio
; Cândido, Eduardo Batista
; Teixeira, Júlio César
.
Revista Brasileira de Ginecologia e Obstetrícia
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6.
Longitudinal bond strength of a universal adhesive and chemical dentin characterization under different acid etching protocols
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GONÇALVES, Lucélia Lemes
; PRAKKI, Anuradha
; SILVA, Tânia Mara da
; BAFAIL, Arwa
; BORTOLATTO, Janaína
; STAVROULLAKIS, Alexander Terry
; GONÇALVES, Sérgio Eduardo de Paiva
.
Abstract Objective This study aimed to analyze the longitudinal bond strength of a universal adhesive and chemically characterize the dentin substrate under different acid etching protocols. Methodology Dentin samples were etched with polyacrylic acid 25% (PAA) for 10 seconds (n=3) and phosphoric acid 32% (PA) for 15 seconds (n=3) and analyzed by Fourier transform infrared spectroscopy – attenuated total reflectance (FTIR-ATR) before and after treatment. For collagen degradation, samples (n=12) were divided into 3 groups: PAA, PA, and Deionized water (control), and analyzed by the quantity of solubilized type I collagen C-terminal cross-linked telopeptides and solubilized C-terminal peptide in relation to total protein concentration (ICTPtp and CTXtp) and by their ultimate tensile strength (UTS). For the adhesive interface analysis, dentin samples (n=72) were divided into 3 groups: PAA, PA, and Self-etch (SE), and subdivided into 2 groups: 24 h (baseline) and 1 year. The following tests were performed: microtensile bond strength (μTBS) (n=48), scanning electron microscopy (SEM) (n=12), and nanoleakage (n=12). Results The FTIR of PAA showed lower reduction of the peaks in the phosphate group when compared to PA. For ICTPtp, PA showed a significantly higher value. For CTXtp, PA and PAA groups failed to statically differ from each other. UTS was significantly lower for PA. For μTBS, storage time significantly affected bond strength. The results were unaffected by the etching protocol. For SEM, after 1 year, PA had little evidence of degradation in the upper third of the adhesive interface in comparison to the other groups. Nanoleakage showed no considerable silver impregnation after 1 year in the SE group. Conclusion The use of PAA prior to a universal adhesive (when compared to PA) represents a less aggressive type of etching to dentin. However, self-etching still seems to be the best option for universal adhesive systems that have functional monomers in their composition. protocols 25 (PAA n=3 n3 n (n=3 32 (PA FTIRATR ATR (FTIR-ATR treatment n=12 n12 12 (n=12 control, control , (control) Cterminal C terminal crosslinked cross linked ICTPtp CTXtp UTS. . (UTS) analysis n=72 n72 72 (n=72 Selfetch Self etch SE, (SE) baseline (baseline performed μTBS (μTBS n=48, n48 n=48 48 (n=48) SEM (SEM n=12, n=12. value protocol However selfetching self composition n= (n= n=1 n1 (n=1 (control (UTS n=7 n7 7 (n=7 (SE n4 n=4 4 (n=48 (n (n=4
7.
Combining silicon, organic matter, and Trichoderma harzianum to mitigate salt stress in forage sorghum silicon matter
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Silva, José Orlando Nunes da
; Silva, Luiz Filipe dos Santos
; Abrantes, Edson Moreira de
; Silva, Leonardo Raimundo da
; Alencar, Eurico Lustosa do Nascimento
; Souza, Eduardo Soares de
; Ferreira-Silva, Sérgio Luiz
; Pessoa, Luiz Guilherme Medeiros
.
ABSTRACT. Salt stress is a major abiotic factor limiting plant growth worldwide, particularly in arid and semiarid regions where excessive groundwater use in irrigation leads to high salt concentrations. To address this issue, this study investigated the efficacy of silicon, either alone or in combination with Trichoderma harzianum and organic matter, in mitigating salt stress in forage sorghum. The experiment took place in a saline Fluvisol in Parnamirim, a semiarid region of Pernambuco, Brazil, and followed a randomized block design with five treatments and four replicates: sorghum (control); sorghum + Si; sorghum + Si + OM (organic matter); sorghum + Si + T (T. harzianum); and sorghum + Si + T + OM. Sorghum plants were assessed over three cycles (initial cut and two regrowths) from June 2021 to April 2022. The combined treatments of Si + OM, Si + T, and Si + T + OM increased plant growth by 42.17, 35.49, and 27.51%, respectively, compared to the control. Similarly, these treatments led to biomass accumulation gains of 39.42, 40.44, and 31.77% in sorghum plants relative to the control. Silicon alone did not yield significant growth or biomass accumulation improvements. The application of silicon in conjunction with T. harzianum and/or organic matter shows promise in enhancing forage sorghum growth under saline stress conditions in semiarid regions. ABSTRACT worldwide concentrations issue Parnamirim Pernambuco Brazil replicates control (control) matter) (T harzianum) initial regrowths 202 2022 4217 42 17 42.17 3549 35 49 35.49 2751 27 51 27.51% respectively Similarly 3942 39 39.42 4044 40 44 40.44 3177 31 77 31.77 improvements andor (control 20 421 4 1 42.1 354 3 35.4 275 2 5 27.51 394 39.4 404 40.4 317 7 31.7 42. 35. 27.5 39. 40. 31. 27.
8.
The Brazilian association of hematology, hemotherapy, and cell therapy (ABHH) and its absolute commitment to ethics and absence of conflicts of interest hematology hemotherapy ABHH (ABHH
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Souza, Carmino Antonio de
; Rego, Eduardo Magalhães
; Ribeiro, Glaciano Nogueira
; Magalhães, Silvia Maria Meira
; Silva, Celso Arrais Rodrigues da
; Passos, Leny Nascimento da Motta
; Covas, Dimas Tadeu
; Tavares, Renato Sampaio
; Hungria, Vania T.de Moraes
; Crusoé, Edvan de Queiroz
; Marques Jr, José Francisco Comenalli
; Chiattone, Carlos Sérgio
; Langhi Junior, Dante
; Pinto Neto, Jorge Vaz
; Laforga, Violete Petitto
; Maiolino, Angelo
.
9.
Prognostic value of programmed cell death ligand 1 (PD-L1) expression in patients with stage III non-small cell lung cancer under different treatment types: a retrospective study PDL1 PDL PD L1 L (PD-L1 nonsmall non small types (PD-L
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Castro, Nicoly Marques de
; Moura, Fernando
; Hada, Aline Lury
; Garcia, Diogo
; Victor, Elivane da Silva
; Schvartsman, Gustavo
; Carvalho, Leonardo
; Fernandes, Milena Lourenço Coleta
; Martins, Rodrigo de Souza
; Silva, Elaine Ferreira da
; Santos, Sarah Silva Mello Batista dos
; Taniwaki, Letícia
; Taranto, Patrícia
; Pontes, Janaina
; Beal, Juliana Rodrigues
; Dutra, Ana Carolina Pereira
; Oliveira Filho, João Bosco de
; Araujo, Sérgio Eduardo Alonso
; Usón Junior, Pedro Luiz Serrano
.
ABSTRACT Objective Currently programmed cell death protein 1 (PD-1) inhibitors in combination with other therapies are being evaluated to determine their efficacy in cancer treatment. However, the effect of PD-ligand (L) 1 expression on disease outcomes in stage III (EC III) non-small cell lung cancer is not completely understood. Therefore, this study aimed to assess the influence of PD-L1 expression on the outcomes of EC III non-small cell lung cancer. Methods This study was conducted on patients diagnosed with EC III non-small cell lung cancer who underwent treatment at a tertiary care hospital. PD-L1 expression was determined using immunohistochemical staining, all patients expressed PD-L1. Survival was estimated using the Kaplan-Meier method. Relationships between variables were assessed using Cox proportional regression models. Results A total of 49 patients (median age=69 years) with EC III non-small cell lung cancer and PD-L1 expression were evaluated. More than half of the patients were men, and most were regular smokers. The patients were treated with neoadjuvant chemotherapy, surgery, or sequential or combined chemotherapy and radiotherapy. The median progression-free survival of the entire cohort was 14.2 months, and the median overall survival was 20 months. There was no significant association between PD-L1 expression and disease progression, clinical characteristics, or overall survival. Conclusions PD-L1 expression was not correlated with EC III non-small cell lung cancer outcomes. Whether these findings differ from the association with immune checkpoint inhibitors remains to be addressed in future studies. PD1 PD (PD-1 However PDligand ligand L (L nonsmall non small understood Therefore PDL1 PDL L1 PD-L hospital staining PDL1. L1. KaplanMeier Kaplan Meier method models 4 age69 age 69 age=6 years men smokers surgery radiotherapy progressionfree progression free 142 14 2 14. months characteristics studies (PD- age6 6 age= (PD
10.
In vitro effect of TiF4/NaF solution on the development of radiation-induced dentin caries TiF4NaF TiFNaF TiF4 NaF TiF radiationinduced radiation induced
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SOUZA, Beatriz Martines de
; FRANCISCO, Eduardo Lista
; BRAGA, Aline Silva
; SANTOS, Paulo Sergio da Silva
; BUZALAF, Marilia Afonso Rabelo
; MAGALHÃES, Ana Carolina
.
Abstract Objective To evaluate the protective effect of an experimental solution containing TiF4/NaF on the development of radiation-induced dentin caries lesions. Methodology bovine root samples were irradiated (70Gy) and distributed as following (n=12/group): Commercial Saliva (BioXtra), NaF (500 ppm F-), TiF4 (500 ppm F), TiF4/NaF (TiF4: 300 ppm F-, NaF: 190 ppm F-), and Phosphate buffer solution (PBS, negative control). Biofilm was produced using biofilm from irradiated patients and McBain saliva (0.2% of sucrose, at 37oC and 5% CO2) for five days. The treatments were applied 1x/day. Colony-forming units (CFU) were counted and demineralization was quantified by transversal microradiography. The ANOVA/Tukey test was applied for all parameters. Results All treatments reduced CFU for total microorganisms. TiF4 reduced Lactobacillus sp. (7.04±0.26 log10 CFU/mL) and mutans streptococci (7.18±0.28) CFU the most, when compared to PBS (7.58±0.21 and 7.75±0.17) and followed by NaF (7.12±0.31 and 7.34±0.22) and TiF4/NaF (7.16±0.35 and 7.29± 0.29). TiF4 and Commercial saliva showed the lowest integrated mineral loss (ΔZ-vol%.mm) (1977±150 and 2062±243, respectively) when compared to PBS (4540±335), followed by NaF (2403±235) and TiF4/NaF (2340±200). Commercial saliva was the only to significantly reduce mineral loss (LD-µm) (111±25) compared to PBS (153±24).Mean mineral loss (R-vol%) decreased by 35.2% for TiF4 (18.2±3.3) when compared to PBS (28.1±2.9) Conclusion: TiF4/NaF has a comparable anti-cariogenic effect to TiF4 and Commercial saliva under the model in this study. TiF4NaF TiFNaF TiF radiationinduced radiation induced lesions 70Gy Gy (70Gy n=12/group n12group ngroup n 12 group (n=12/group) BioXtra, BioXtra , (BioXtra) 500 (50 F, F F-) F) (TiF4 30 F- 19 PBS, (PBS control. control . control) 0.2% 02 0 2 (0.2 sucrose oC 5 CO2 CO days 1xday xday 1x day x 1x/day Colonyforming Colony forming (CFU microradiography ANOVATukey ANOVA Tukey parameters microorganisms sp 7.04±0.26 704026 7 04 26 (7.04±0.2 log log1 CFU/mL CFUmL mL 7.18±0.28 718028 18 28 (7.18±0.28 most 7.58±0.21 758021 58 21 (7.58±0.2 7.75±0.17 775017 75 17 7.12±0.31 712031 31 (7.12±0.3 7.34±0.22 734022 34 22 7.16±0.35 716035 16 35 (7.16±0.3 729 29 7.29 0.29. 029 0.29 0.29) ΔZvol%.mm ΔZvolmm ΔZ vol%.mm vol mm (ΔZ-vol%.mm 1977±150 1977150 1977 150 (1977±15 2062243 2062 243 2062±243 respectively 4540±335, 4540335 4540±335 4540 335 (4540±335) 2403±235 2403235 2403 235 (2403±235 2340±200. 2340200 2340±200 2340 200 (2340±200) LDµm LD µm (LD-µm 111±25 11125 111 25 (111±25 153±24.Mean 15324Mean Mean 153±24 .Mean 153 24 Rvol% Rvol R vol% (R-vol% 352 35.2 18.2±3.3 18233 3 (18.2±3.3 28.1±2.9 28129 1 9 (28.1±2.9 Conclusion anticariogenic anti cariogenic study (n=12/group (BioXtra 50 (5 (TiF 0.2 (0. 7.04±0.2 70402 (7.04±0. 7.18±0.2 71802 (7.18±0.2 7.58±0.2 75802 (7.58±0. 7.75±0.1 77501 7.12±0.3 71203 (7.12±0. 7.34±0.2 73402 7.16±0.3 71603 (7.16±0. 72 7.2 ΔZvol volmm 1977±15 197715 197 15 (1977±1 206224 206 2062±24 454033 4540±33 454 33 (4540±335 2403±23 240323 240 23 (2403±23 234020 2340±20 234 20 (2340±200 111±2 1112 11 (111±2 15324 153±2 (R-vol 35. 18.2±3. 1823 (18.2±3. 28.1±2. 2812 (28.1±2. ( 0. (0 7.04±0. 7040 (7.04±0 7.18±0. 7180 (7.18±0. 7.58±0. 7580 (7.58±0 7.75±0. 7750 7.12±0. 7120 (7.12±0 7.34±0. 7340 7.16±0. 7160 (7.16±0 7. 1977±1 19771 (1977± 20622 2062±2 45403 4540±3 45 (4540±33 2403±2 24032 (2403±2 23402 2340±2 (2340±20 111± (111± 1532 153± 18.2±3 182 (18.2±3 28.1±2 281 (28.1±2 7.04±0 704 (7.04± 7.18±0 718 (7.18±0 7.58±0 758 (7.58± 7.75±0 775 7.12±0 712 (7.12± 7.34±0 734 7.16±0 716 (7.16± 1977± (1977 2062± 4540± 4 (4540±3 2403± (2403± 2340± (2340±2 (111 18.2± (18.2± 28.1± (28.1± 7.04± 70 (7.04 7.18± 71 (7.18± 7.58± (7.58 7.75± 77 7.12± (7.12 7.34± 73 7.16± (7.16 (197 (4540± (2403 (2340± (11 18.2 (18.2 28.1 (28.1 7.04 (7.0 7.18 (7.18 7.58 (7.5 7.75 7.12 (7.1 7.34 7.16 (19 (4540 (240 (2340 (1 18. (18. 28. (28. 7.0 (7. 7.1 7.5 7.7 7.3 (454 (24 (234 (18 (28 (7 (45 (2 (23 (4
11.
Diretriz Brasileira de Ergometria em População Adulta – 2024 202 20 2
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Carvalho, Tales de
; Freitas, Odilon Gariglio Alvarenga de
; Chalela, William Azem
; Hossri, Carlos Alberto Cordeiro
; Milani, Mauricio
; Buglia, Susimeire
; Precoma, Dalton Bertolim
; Falcão, Andréa Maria Gomes Marinho
; Mastrocola, Luiz Eduardo
; Castro, Iran
; Albuquerque, Pedro Ferreira de
; Coutinho, Ricardo Quental
; Brito, Fabio Sandoli de
; Alves, Josmar de Castro
; Serra, Salvador Manoel
; Santos, Mauro Augusto dos
; Colombo, Clea Simone Sabino de Souza
; Stein, Ricardo
; Herdy, Artur Haddad
; Silveira, Anderson Donelli da
; Castro, Claudia Lucia Barros de
; Silva, Miguel Morita Fernandes da
; Meneghello, Romeu Sergio
; Ritt, Luiz Eduardo Fonteles
; Malafaia, Felipe Lopes
; Marinucci, Leonardo Filipe Benedeti
; Pena, José Luiz Barros
; Almeida, Antônio Eduardo Monteiro de
; Vieira, Marcelo Luiz Campos
; Stier Júnior, Arnaldo Laffitte
.
12.
Tendência Temporal no Implante Percutâneo de Bioprótese Aórtica: Análise de 10 Anos do Registro TAVIDOR Aórtica 1
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Esteves, Vinicius
; Andrade, Pedro Beraldo de
; Zukowski, Cleverson Neves
; Araujo, Edmur
; Bezerra, Cristiano Guedes
; Oliveira, Adriano Dourado
; Melo, Eduardo Pessoa de
; Gama, Gustavo
; Cantarelli, Rodrigo
; Mattos, Luiz Alberto Piva e
; Tedeschi, Angelo
; Loures, Vitor Alves
; Vahle, Vitor
; Silva, Guilherme Barreto Gameiro
; Rati, Miguel Antonio Neves
; Lopes, Augusto Celso
; Fé Filho, Nilson de Moura
; Alves, Gustavo
; Tavares Filho, Sérgio Costa
; Kreimer, Sergio
; Tebet, Marden
; Maia, Felipe
; Oliveira, Maurício Sales de
; Fonseca, Alberto
; Camiletti, Angelina
; Albuquerque, Denilson Campos de
; Souza, Olga Ferreira de
.
Resumo Fundamento O implante percutâneo de bioprótese valvar aórtica (TAVI) consolidou-se como opção terapêutica da estenose aórtica de grau importante. Dados sobre as características evolutivas dos procedimentos e dos resultados obtidos com a técnica ao longo da última década, em escala nacional, são desconhecidos. Objetivos Analisar a tendência temporal referente ao perfil demográfico, características dos procedimentos e desfechos hospitalares de pacientes submetidos a TAVI na Rede D’Or São Luiz. Métodos Registro observacional envolvendo 29 instituições nacionais. Comparou-se características dos procedimentos realizados de 2012 a 2017 (Grupo 1) e de 2018 a 2023 (Grupo 2). Foram considerados significantes os resultados com valor de p < 0,05. Resultados Foram analisados 661 casos, 95 pertencentes ao Grupo 1 e 566 ao Grupo 2. A média de idade foi 81,1 anos. Observou-se no Grupo 1 maior prevalência de pacientes em classe funcional III ou IV e escore de risco > 8%. Foi mais frequente o emprego de anestesia geral, monitorização ecocardiográfica transesofágica e via de acesso por dissecção. Maior taxa de sucesso do procedimento (95,4% versus 89,5%; p = 0,018) foi aferida em implantes efetivados a partir de 2018, assim como menor mortalidade (3,9% versus 11,6%; p = 0,004) e necessidade de marcapasso definitivo (8,5% versus 17,9%; p = 0,008). Conclusões A análise temporal de 10 anos do Registro TAVIDOR demonstra uma queda na complexidade clínica dos pacientes. Além disso, o avanço para técnicas de implante minimalistas, somadas à evolução tecnológica dos dispositivos, podem ter contribuído para desfechos favoráveis dentre aqueles cujo implante ocorreu no último quinquênio. (TAVI consolidouse consolidou se importante década nacional desconhecidos demográfico DOr D Or Luiz 2 nacionais Comparouse Comparou 201 202 . 2) 005 0 05 0,05 66 casos 9 56 811 81 81, Observouse Observou 8 8% geral dissecção 95,4% 954 4 (95,4 89,5% 895 89 5 0,018 0018 018 3,9% 39 3 (3,9 11,6% 116 11 6 0,004 0004 004 8,5% 85 (8,5 17,9% 179 17 0,008. 0008 0,008 008 0,008) disso minimalistas dispositivos quinquênio 20 00 0,0 95,4 (95, 89,5 0,01 001 01 3,9 (3, 11,6 0,00 000 8,5 (8, 17,9 0, 95, (95 89, 3, (3 11, 8, (8 17, (9 (
Abstract Background Transcatheter aortic valve implantation (TAVI) has established itself as the preferential strategy to approach severe aortic stenosis. Information on procedural improvements and nationwide results obtained with the technique throughout the past decade are unknown. Objectives To assess the temporal variation of the demographic profile, procedural characteristics, and in-hospital outcomes of patients undergoing TAVI procedures at the Rede D’Or São Luiz. Methods Observational registry comprising 29 national institutions, comparing the characteristics of the TAVI procedures performed from 2012 to 2017 (Group 1) to those performed from 2018 to 2023 (Group 2). The statistical significance level adopted was p < 0.05. Results This study assessed 661 patients, 95 in Group 1 and 566 in Group 2, with a mean age of 81.1 years. Group 1 patients had a higher prevalence of New York Heart Association functional class III or IV and STS risk score > 8%. In addition, they more often underwent general anesthesia, transesophageal echocardiographic monitoring, and access through femoral dissection. Group 2 patients had a higher success rate of the TAVI procedure (95.4% versus 89.5%; p = 0.018), lower mortality (3.9% versus 11.6%; p = 0.004), and less often needed permanent pacemaker implantation (8.5% versus 17.9%; p = 0.008). Conclusions The 10-year temporal trends analysis of the TAVIDOR Registry shows a reduction in patients’ clinical complexity over time. Furthermore, the advance to minimalistic implantation techniques, added to the technological evolution of the devices, may have contributed to the favorable outcomes observed among those whose implantation occurred in the last 5 years studied. (TAVI stenosis unknown profile inhospital hospital DOr D Or Luiz institutions 201 202 2. . 2) 005 0 05 0.05 66 9 56 811 81 81. 8 8% addition anesthesia monitoring dissection 95.4% 954 4 (95.4 89.5% 895 89 0.018, 0018 0.018 , 018 0.018) 3.9% 39 3 (3.9 11.6% 116 11 6 0.004, 0004 0.004 004 0.004) 8.5% 85 (8.5 17.9% 179 17 0.008. 0008 0.008 008 0.008) 10year year 10 time Furthermore techniques devices studied 20 00 0.0 95.4 (95. 89.5 001 0.01 01 3.9 (3. 11.6 000 0.00 8.5 (8. 17.9 0. 95. (95 89. 3. (3 11. 8. (8 17. (9 (
13.
The impact of a breast cancer diagnosis on marital outcomes and factors associated with divorce and separation
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Werutsky, Gustavo
; Lopes, Mahira
; Jesus, Rafaela Gomes de
; Gazola, Antonia Angeli
; Pellegrini, Rodrigo Azevedo
; Rebelatto, Taiane Francieli
; Freitas, Laura von Wallwitz
; Heck, Ana Paula
; Silva, Arthur Ferreira da
; Rodrigues, Matheus Füehr
; Gössling, Gustavo
; Giacomazzi, Juliana
; Rocha, Matheus Soares
; Rosa, Daniela Dornelles
; Barrios, Carlos Henrique
; Cronemberger, Eduardo Henrique
; Queiroz, Geraldo Silva
; Bines, José
; Simon, Sérgio Daniel
; Fay, Andre Poisl
.
Abstract Objective To analyze marital outcomes, divorce or separation, and its association with demographic, socioeconomic, and clinicopathological factors among breast cancer (BC) survivors after 2-years of diagnosis. Methods We performed a retrospective analysis of marital status at baseline and at years 1 and 2 of follow-up of women aged ≥ 18 years diagnosed with invasive BC participating in the AMAZONA III (GBECAM0115) study. The BC diagnosis occurred between January 2016 and March 2018 at 23 institutions in Brazil. Results Of the 2974 women enrolled in AMAZONA III, 599 were married or living under common law at baseline. Divorce or separation occurred in 35 (5.8%) patients at 2 years of follow-up. In the multivariate analysis, public health insurance coverage was associated with a higher risk of marital status change (8.25% vs. 2.79%, RR 3.09, 95% CI 1.39 - 7.03, p = 0.007). Women who underwent mastectomy, adenomastectomy or skin-sparing mastectomy were associated with a higher risk of divorce or separation (8.1% vs. 4.49%, RR 1.97, 95 CI 1.04 – 3.72, p = 0.0366) than those who underwent breast-conserving surgery. Conclusion Women covered by the public health system and those who underwent mastectomy, adenomastectomy or skin-sparing mastectomy were associated with a higher risk of divorce or separation. This evidence further supports the idea that long-term marital stability is associated with a complex interplay between socioeconomic conditions and stressors, such as BC diagnosis and treatment. ClinicalTrials Registration: NCT02663973. outcomes demographic (BC 2years followup follow up GBECAM0115 GBECAM (GBECAM0115 study 201 Brazil 297 59 3 5.8% 58 5 8 (5.8% followup. up. 8.25% 825 25 (8.25 vs 279 79 2.79% 309 09 3.09 139 39 1.3 703 7 03 7.03 0.007. 0007 0.007 . 0 007 0.007) skinsparing skin sparing 8.1% 81 (8.1 449 4 49 4.49% 197 97 1.97 9 104 04 1.0 372 72 3.72 0.0366 00366 0366 breastconserving conserving surgery longterm long term stressors treatment Registration NCT02663973 NCT GBECAM011 (GBECAM011 20 29 5.8 (5.8 8.25 82 (8.2 27 2.79 30 3.0 13 1. 70 7.0 000 0.00 00 8.1 (8. 44 4.49 19 1.9 10 37 3.7 0.036 0036 036 NCT0266397 GBECAM01 (GBECAM01 5. (5. 8.2 2.7 3. 7. 0.0 8. (8 4.4 0.03 003 NCT026639 GBECAM0 (GBECAM0 (5 2. 0. ( 4. NCT02663 (GBECAM NCT0266 NCT026 NCT02 NCT0
14.
Translation, transcultural adaptation into Brazilian Portuguese and concurrent validity of the rheumatoid arthritis assessment scale (RAKAS–13/Brazil) Translation RAKAS–13/Brazil RAKAS13Brazil RAKASBrazil RAKAS 13 Brazil (RAKAS–13/Brazil 1
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Mineiro, Lindomar
; Silva, Tamires Terezinha Gallo da
; Valderramas, Silvia Regina
; Kowalski, Sergio Candido
; Paiva, Eduardo dos Santos
; Gomes, Anna Raquel Silveira
.
Abstract Background Knowledge of patients about Rheumatoid Arthritis (RA) is a necessary aspect to better approach self-management support in a patient-centered manner. The research instrument known as the Rheumatoid Arthritis Knowledge Assessment Scale (RAKAS), consisting of 13 items, is simple, reliable and reproducible, and can be applied in both clinical practice and research protocols. Objectives This study aimed to translate and culturally adapt the RAKAS vocabulary into Brazilian Portuguese and to evaluate its concurrent validity. Methods The RAKAS was translated into Brazilian Portuguese and administered to 52 elderly women with RA recruited between May 2021 and May 2022. Concurrent validity was assessed using the Spearman's correlation coefficient between RAKAS and Patient Knowledge Questionnaire (PKQ). Results The participants considered RAKAS-13/BRAZIL easy to understand and did not report any doubts in answering the final version. Concurrent validity of the RAKAS–13/BRAZIL was low compared to the PKQ (ρ = 0.283, p = 0.038). Conclusion The Brazilian Portuguese version of the RAKAS (RAKAS–13/BRASIL) proved to be a questionnaire that was easy and quick to administer to assess patient knowledge about Rheumatoid Arthritis, despite its low correlation with the PKQ in the present study. (RA selfmanagement self management patientcentered centered manner RAKAS, , (RAKAS) 1 items simple reproducible protocols 5 202 2022 Spearmans Spearman s PKQ. . (PKQ) RAKAS13/BRAZIL RAKAS13BRAZIL RAKASBRAZIL 13/BRAZIL BRAZIL ρ 0283 0 283 0.283 0.038. 0038 0.038 038 0.038) RAKAS–13/BRASIL RAKAS13BRASIL RAKASBRASIL BRASIL (RAKAS–13/BRASIL (RAKAS 20 (PKQ RAKAS13 13BRAZIL 028 28 0.28 003 0.03 03 2 RAKAS1 02 0.2 00 0.0 0.
15.
Catálogo Taxonômico da Fauna do Brasil: Setting the baseline knowledge on the animal diversity in Brazil Brasil
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Boeger, Walter A.
; Valim, Michel P.
; Zaher, Hussam
; Rafael, José A.
; Forzza, Rafaela C.
; Percequillo, Alexandre R.
; Serejo, Cristiana S.
; Garraffoni, André R.S.
; Santos, Adalberto J.
; Slipinski, Adam
; Linzmeier, Adelita M.
; Calor, Adolfo R.
; Garda, Adrian A.
; Kury, Adriano B.
; Fernandes, Agatha C.S.
; Agudo-Padrón, Aisur I.
; Akama, Alberto
; Silva Neto, Alberto M. da
; Burbano, Alejandro L.
; Menezes, Aleksandra
; Pereira-Colavite, Alessandre
; Anichtchenko, Alexander
; Lees, Alexander C.
; Bezerra, Alexandra M.R.
; Domahovski, Alexandre C.
; Pimenta, Alexandre D.
; Aleixo, Alexandre L.P.
; Marceniuk, Alexandre P.
; Paula, Alexandre S. de
; Somavilla, Alexandre
; Specht, Alexandre
; Camargo, Alexssandro
; Newton, Alfred F.
; Silva, Aline A.S. da
; Santos, Aline B. dos
; Tassi, Aline D.
; Aragão, Allan C.
; Santos, Allan P.M.
; Migotto, Alvaro E.
; Mendes, Amanda C.
; Cunha, Amanda
; Chagas Júnior, Amazonas
; Sousa, Ana A.T. de
; Pavan, Ana C.
; Almeida, Ana C.S.
; Peronti, Ana L.B.G.
; Henriques-Oliveira, Ana L.
; Prudente, Ana L.
; Tourinho, Ana L.
; Pes, Ana M.O.
; Carmignotto, Ana P.
; Wengrat, Ana P.G. da Silva
; Dornellas, Ana P.S.
; Molin, Anamaria Dal
; Puker, Anderson
; Morandini, André C.
; Ferreira, André da S.
; Martins, André L.
; Esteves, André M.
; Fernandes, André S.
; Roza, André S.
; Köhler, Andreas
; Paladini, Andressa
; Andrade, Andrey J. de
; Pinto, Ângelo P.
; Salles, Anna C. de A.
; Gondim, Anne I.
; Amaral, Antonia C.Z.
; Rondón, Antonio A.A.
; Brescovit, Antonio
; Lofego, Antônio C.
; Marques, Antonio C.
; Macedo, Antonio
; Andriolo, Artur
; Henriques, Augusto L.
; Ferreira Júnior, Augusto L.
; Lima, Aurino F. de
; Barros, Ávyla R. de A.
; Brito, Ayrton do R.
; Romera, Bárbara L.V.
; Vasconcelos, Beatriz M.C. de
; Frable, Benjamin W.
; Santos, Bernardo F.
; Ferraz, Bernardo R.
; Rosa, Brunno B.
; Sampaio, Brunno H.L.
; Bellini, Bruno C.
; Clarkson, Bruno
; Oliveira, Bruno G. de
; Corrêa, Caio C.D.
; Martins, Caleb C.
; Castro-Guedes, Camila F. de
; Souto, Camilla
; Bicho, Carla de L.
; Cunha, Carlo M.
; Barboza, Carlos A. de M.
; Lucena, Carlos A.S. de
; Barreto, Carlos
; Santana, Carlos D.C.M. de
; Agne, Carlos E.Q.
; Mielke, Carlos G.C.
; Caetano, Carlos H.S.
; Flechtmann, Carlos H.W.
; Lamas, Carlos J.E.
; Rocha, Carlos
; Mascarenhas, Carolina S.
; Margaría, Cecilia B.
; Waichert, Cecilia
; Digiani, Celina
; Haddad, Célio F.B.
; Azevedo, Celso O.
; Benetti, Cesar J.
; Santos, Charles M.D. dos
; Bartlett, Charles R.
; Bonvicino, Cibele
; Ribeiro-Costa, Cibele S.
; Santos, Cinthya S.G.
; Justino, Cíntia E.L.
; Canedo, Clarissa
; Bonecker, Claudia C.
; Santos, Cláudia P.
; Carvalho, Claudio J.B. de
; Gonçalves, Clayton C.
; Galvão, Cleber
; Costa, Cleide
; Oliveira, Cléo D.C. de
; Schwertner, Cristiano F.
; Andrade, Cristiano L.
; Pereira, Cristiano M.
; Sampaio, Cristiano
; Dias, Cristina de O.
; Lucena, Daercio A. de A.
; Manfio, Daiara
; Amorim, Dalton de S.
; Queiroz, Dalva L. de
; Queiroz, Dalva L. de
; Colpani, Daniara
; Abbate, Daniel
; Aquino, Daniel A.
; Burckhardt, Daniel
; Cavallari, Daniel C.
; Prado, Daniel de C. Schelesky
; Praciano, Daniel L.
; Basílio, Daniel S.
; Bená, Daniela de C.
; Toledo, Daniela G.P. de
; Takiya, Daniela M.
; Fernandes, Daniell R.R.
; Ament, Danilo C.
; Cordeiro, Danilo P.
; Silva, Darliane E.
; Pollock, Darren A.
; Muniz, David B.
; Gibson, David I.
; Nogueira, David S.
; Marques, Dayse W.A.
; Lucatelli, Débora
; Garcia, Deivys M.A.
; Baêta, Délio
; Ferreira, Denise N.M.
; Rueda-Ramírez, Diana
; Fachin, Diego A.
; Souza, Diego de S.
; Rodrigues, Diego F.
; Pádua, Diego G. de
; Barbosa, Diego N.
; Dolibaina, Diego R.
; Amaral, Diogo C.
; Chandler, Donald S.
; Maccagnan, Douglas H.B.
; Caron, Edilson
; Carvalho, Edrielly
; Adriano, Edson A.
; Abreu Júnior, Edson F. de
; Pereira, Edson H.L.
; Viegas, Eduarda F.G.
; Carneiro, Eduardo
; Colley, Eduardo
; Eizirik, Eduardo
; Santos, Eduardo F. dos
; Shimbori, Eduardo M.
; Suárez-Morales, Eduardo
; Arruda, Eliane P. de
; Chiquito, Elisandra A.
; Lima, Élison F.B.
; Castro, Elizeu B. de
; Orlandin, Elton
; Nascimento, Elynton A. do
; Razzolini, Emanuel
; Gama, Emanuel R.R.
; Araujo, Enilma M. de
; Nishiyama, Eric Y.
; Spiessberger, Erich L.
; Santos, Érika C.L. dos
; Contreras, Eugenia F.
; Galati, Eunice A.B.
; Oliveira Junior, Evaldo C. de
; Gallardo, Fabiana
; Hernandes, Fabio A.
; Lansac-Tôha, Fábio A.
; Pitombo, Fabio B.
; Dario, Fabio Di
; Santos, Fábio L. dos
; Mauro, Fabio
; Nascimento, Fabio O. do
; Olmos, Fabio
; Amaral, Fabio R.
; Schunck, Fabio
; Godoi, Fábio S. P. de
; Machado, Fabrizio M.
; Barbo, Fausto E.
; Agrain, Federico A.
; Ribeiro, Felipe B.
; Moreira, Felipe F.F.
; Barbosa, Felipe F.
; Silva, Fenanda S.
; Cavalcanti, Fernanda F.
; Straube, Fernando C.
; Carbayo, Fernando
; Carvalho Filho, Fernando
; Zanella, Fernando C.V.
; Jacinavicius, Fernando de C.
; Farache, Fernando H.A.
; Leivas, Fernando
; Dias, Fernando M.S.
; Mantellato, Fernando
; Vaz-de-Mello, Fernando Z.
; Gudin, Filipe M.
; Albuquerque, Flávio
; Molina, Flavio B.
; Passos, Flávio D.
; Shockley, Floyd W.
; Pinheiro, Francielly F.
; Mello, Francisco de A.G. de
; Nascimento, Francisco E. de L.
; Franco, Francisco L.
; Oliveira, Francisco L. de
; Melo, Francisco T. de V.
; Quijano, Freddy R.B.
; Salles, Frederico F.
; Biffi, Gabriel
; Queiroz, Gabriel C.
; Bizarro, Gabriel L.
; Hrycyna, Gabriela
; Leviski, Gabriela
; Powell, Gareth S.
; Santos, Geane B. dos
; Morse, Geoffrey E.
; Brown, George
; Mattox, George M.T.
; Zimbrão, Geraldo
; Carvalho, Gervásio S.
; Miranda, Gil F.G.
; Moraes, Gilberto J. de
; Lourido, Gilcélia M.
; Neves, Gilmar P.
; Moreira, Gilson R.P.
; Montingelli, Giovanna G.
; Maurício, Giovanni N.
; Marconato, Gláucia
; Lopez, Guilherme E.L.
; Silva, Guilherme L. da
; Muricy, Guilherme
; Brito, Guilherme R.R.
; Garbino, Guilherme S.T.
; Flores, Gustavo E.
; Graciolli, Gustavo
; Libardi, Gustavo S.
; Proctor, Heather C.
; Gil-Santana, Helcio R.
; Varella, Henrique R.
; Escalona, Hermes E.
; Schmitz, Hermes J.
; Rodrigues, Higor D.D.
; Galvão Filho, Hilton de C.
; Quintino, Hingrid Y.S.
; Pinto, Hudson A.
; Rainho, Hugo L.
; Miyahira, Igor C.
; Gonçalves, Igor de S.
; Martins, Inês X.
; Cardoso, Irene A.
; Oliveira, Ismael B. de
; Franz, Ismael
; Fernandes, Itanna O.
; Golfetti, Ivan F.
; S. Campos-Filho, Ivanklin
; Oliveira, Ivo de S.
; Delabie, Jacques H.C.
; Oliveira, Jader de
; Prando, Jadila S.
; Patton, James L.
; Bitencourt, Jamille de A.
; Silva, Janaina M.
; Santos, Jandir C.
; Arruda, Janine O.
; Valderrama, Jefferson S.
; Dalapicolla, Jeronymo
; Oliveira, Jéssica P.
; Hájek, Jiri
; Morselli, João P.
; Narita, João P.
; Martin, João P.I.
; Grazia, Jocélia
; McHugh, Joe
; Cherem, Jorge J.
; Farias Júnior, José A.S.
; Fernandes, Jose A.M.
; Pacheco, José F.
; Birindelli, José L.O.
; Rezende, José M.
; Avendaño, Jose M.
; Duarte, José M. Barbanti
; Ribeiro, José R. Inácio
; Mermudes, José R.M.
; Pujol-Luz, José R.
; Santos, Josenilson R. dos
; Câmara, Josenir T.
; Teixeira, Joyce A.
; Prado, Joyce R. do
; Botero, Juan P.
; Almeida, Julia C.
; Kohler, Julia
; Gonçalves, Julia P.
; Beneti, Julia S.
; Donahue, Julian P.
; Alvim, Juliana
; Almeida, Juliana C.
; Segadilha, Juliana L.
; Wingert, Juliana M.
; Barbosa, Julianna F.
; Ferrer, Juliano
; Santos, Juliano F. dos
; Kuabara, Kamila M.D.
; Nascimento, Karine B.
; Schoeninger, Karine
; Campião, Karla M.
; Soares, Karla
; Zilch, Kássia
; Barão, Kim R.
; Teixeira, Larissa
; Sousa, Laura D. do N.M. de
; Dumas, Leandro L.
; Vieira, Leandro M.
; Azevedo, Leonardo H.G.
; Carvalho, Leonardo S.
; Souza, Leonardo S. de
; Rocha, Leonardo S.G.
; Bernardi, Leopoldo F.O.
; Vieira, Letícia M.
; Johann, Liana
; Salvatierra, Lidianne
; Oliveira, Livia de M.
; Loureiro, Lourdes M.A. El-moor
; Barreto, Luana B.
; Barros, Luana M.
; Lecci, Lucas
; Camargos, Lucas M. de
; Lima, Lucas R.C.
; Almeida, Lucia M.
; Martins, Luciana R.
; Marinoni, Luciane
; Moura, Luciano de A.
; Lima, Luciano
; Naka, Luciano N.
; Miranda, Lucília S.
; Salik, Lucy M.
; Bezerra, Luis E.A.
; Silveira, Luis F.
; Campos, Luiz A.
; Castro, Luiz A.S. de
; Pinho, Luiz C.
; Silveira, Luiz F.L.
; Iniesta, Luiz F.M.
; Tencatt, Luiz F.C.
; Simone, Luiz R.L.
; Malabarba, Luiz R.
; Cruz, Luiza S. da
; Sekerka, Lukas
; Barros, Lurdiana D.
; Santos, Luziany Q.
; Skoracki, Maciej
; Correia, Maira A.
; Uchoa, Manoel A.
; Andrade, Manuella F.G.
; Hermes, Marcel G.
; Miranda, Marcel S.
; Araújo, Marcel S. de
; Monné, Marcela L.
; Labruna, Marcelo B.
; Santis, Marcelo D. de
; Duarte, Marcelo
; Knoff, Marcelo
; Nogueira, Marcelo
; Britto, Marcelo R. de
; Melo, Marcelo R.S. de
; Carvalho, Marcelo R. de
; Tavares, Marcelo T.
; Kitahara, Marcelo V.
; Justo, Marcia C.N.
; Botelho, Marcia J.C.
; Couri, Márcia S.
; Borges-Martins, Márcio
; Felix, Márcio
; Oliveira, Marcio L. de
; Bologna, Marco A.
; Gottschalk, Marco S.
; Tavares, Marcos D.S.
; Lhano, Marcos G.
; Bevilaqua, Marcus
; Santos, Marcus T.T.
; Domingues, Marcus V.
; Sallum, Maria A.M.
; Digiani, María C.
; Santarém, Maria C.A.
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; Passos, Maria I. da S. dos
; Felippe-Bauer, Maria L.
; Cherman, Mariana A.
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; Bartz, Marie L.C.
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; Cohn-Haft, Mario
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; Demite, Peterson R.
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; Silva, Rafael A.P.F.
; Moura, Rafael B. de
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; Silva, Rafaela A. da
; Falaschi, Rafaela L.
; Cordeiro, Ralf T.S.
; Mello, Ramon J.C.L.
; Singer, Randal A.
; Querino, Ranyse B.
; Heleodoro, Raphael A.
; Castilho, Raphael de C.
; Constantino, Reginaldo
; Guedes, Reinaldo C.
; Carrenho, Renan
; Gomes, Renata S.
; Gregorin, Renato
; Machado, Renato J.P.
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; Silva, Ricardo B.
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; Brugnera, Ricaro
; Leschen, Richard A.B.
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; Dios, Rodrigo de V.P.
; Johnsson, Rodrigo
; Feitosa, Rodrigo M.
; Hutchings, Roger W.
; Lara, Rogéria I.R.
; Rossi, Rogério V.
; Gerstmeier, Roland
; Ochoa, Ronald
; Hutchings, Rosa S.G.
; Ale-Rocha, Rosaly
; Rocha, Rosana M. da
; Tidon, Rosana
; Brito, Rosangela
; Pellens, Roseli
; Santos, Sabrina R. dos
; Santos, Sandra D. dos
; Paiva, Sandra V.
; Santos, Sandro
; Oliveira, Sarah S. de
; Costa, Sávio C.
; Gardner, Scott L.
; Leal, Sebastián A. Muñoz
; Aloquio, Sergio
; Bonecker, Sergio L.C.
; Bueno, Sergio L. de S.
; Almeida, Sérgio M. de
; Stampar, Sérgio N.
; Andena, Sérgio R.
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; Lima, Sheila P.
; Gadelha, Sian de S.
; Thiengo, Silvana C.
; Cohen, Simone C.
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; Rosa, Simone P.
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; Letana, Sócrates D.
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; Andrade, Sonia C.S.
; Dávila, Stephane
; Vaz, Stéphanie
; Peck, Stewart B.
; Christo, Susete W.
; Cunha, Suzan B.Z.
; Gomes, Suzete R.
; Duarte, Tácio
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; Marques, Taísa
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; Lima, Tarcilla C. de
; Sepulveda, Tatiana A.
; Maria, Tatiana F.
; Ruschel, Tatiana P.
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; Marinho, Thais A.
; Almeida, Thaís M. de
; Miranda, Thaís P.
; Freitas, Thales R.O.
; Pereira, Thalles P.L.
; Zacca, Thamara
; Pacheco, Thaynara L.
; Martins, Thiago F.
; Alvarenga, Thiago M.
; Carvalho, Thiago R. de
; Polizei, Thiago T.S.
; McElrath, Thomas C.
; Henry, Thomas
; Pikart, Tiago G.
; Porto, Tiago J.
; Krolow, Tiago K.
; Carvalho, Tiago P.
; Lotufo, Tito M. da C.
; Caramaschi, Ulisses
; Pinheiro, Ulisses dos S.
; Pardiñas, Ulyses F.J.
; Maia, Valéria C.
; Tavares, Valeria
; Costa, Valmir A.
; Amaral, Vanessa S. do
; Silva, Vera C.
; Wolff, Vera R. dos S.
; Slobodian, Verônica
; Silva, Vinícius B. da
; Espíndola, Vinicius C.
; Costa-Silva, Vinicius da
; Bertaco, Vinicius de A.
; Padula, Vinícius
; Ferreira, Vinicius S.
; Silva, Vitor C.P. da
; Piacentini, Vítor de Q.
; Sandoval-Gómez, Vivian E.
; Trevine, Vivian
; Sousa, Viviane R.
; Sant’Anna, Vivianne B. de
; Mathis, Wayne N.
; Souza, Wesley de O.
; Colombo, Wesley D.
; Tomaszewska, Wioletta
; Wosiacki, Wolmar B.
; Ovando, Ximena M.C.
; Leite, Yuri L.R.
.
ABSTRACT The limited temporal completeness and taxonomic accuracy of species lists, made available in a traditional manner in scientific publications, has always represented a problem. These lists are invariably limited to a few taxonomic groups and do not represent up-to-date knowledge of all species and classifications. In this context, the Brazilian megadiverse fauna is no exception, and the Catálogo Taxonômico da Fauna do Brasil (CTFB) (http://fauna.jbrj.gov.br/), made public in 2015, represents a database on biodiversity anchored on a list of valid and expertly recognized scientific names of animals in Brazil. The CTFB is updated in near real time by a team of more than 800 specialists. By January 1, 2024, the CTFB compiled 133,691 nominal species, with 125,138 that were considered valid. Most of the valid species were arthropods (82.3%, with more than 102,000 species) and chordates (7.69%, with over 11,000 species). These taxa were followed by a cluster composed of Mollusca (3,567 species), Platyhelminthes (2,292 species), Annelida (1,833 species), and Nematoda (1,447 species). All remaining groups had less than 1,000 species reported in Brazil, with Cnidaria (831 species), Porifera (628 species), Rotifera (606 species), and Bryozoa (520 species) representing those with more than 500 species. Analysis of the CTFB database can facilitate and direct efforts towards the discovery of new species in Brazil, but it is also fundamental in providing the best available list of valid nominal species to users, including those in science, health, conservation efforts, and any initiative involving animals. The importance of the CTFB is evidenced by the elevated number of citations in the scientific literature in diverse areas of biology, law, anthropology, education, forensic science, and veterinary science, among others. publications problem uptodate up date classifications context exception (CTFB http//fauna.jbrj.gov.br/, httpfaunajbrjgovbr http //fauna.jbrj.gov.br/ , jbrj gov br (http://fauna.jbrj.gov.br/) 2015 Brazil 80 specialists 1 2024 133691 133 691 133,69 125138 125 138 125,13 82.3%, 823 82 3 (82.3% 102000 102 000 102,00 7.69%, 769 7 69 (7.69% 11000 11 11,00 . 3,567 3567 567 (3,56 2,292 2292 2 292 (2,29 1,833 1833 833 (1,83 1,447 1447 447 (1,44 1000 1,00 831 (83 628 (62 606 (60 520 (52 50 users science health biology law anthropology education others http//fauna.jbrj.gov.br/ faunajbrjgovbr //fauna.jbrj.gov.br (http://fauna.jbrj.gov.br/ 201 8 202 13369 13 133,6 12513 12 125,1 82.3% (82.3 10200 10 00 102,0 7.69% 76 6 (7.69 1100 11,0 3,56 356 56 (3,5 2,29 229 29 (2,2 1,83 183 83 (1,8 1,44 144 44 (1,4 100 1,0 (8 62 (6 60 52 (5 5 http//fauna.jbrj.gov.br (http://fauna.jbrj.gov.br 20 1336 133, 1251 125, 82.3 (82. 1020 0 102, 7.69 (7.6 110 11, 3,5 35 (3, 2,2 22 (2, 1,8 18 (1, 1,4 14 4 ( 82. (82 7.6 (7. 3, (3 2, (2 (1 7. (7
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