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1.
Angle-closure glaucoma associated with vitreous prolapse after neodymium-doped yttrium-aluminum-garnet laser posterior capsulotomy Angleclosure Angle closure neodymiumdoped neodymium doped yttriumaluminumgarnet yttrium aluminum garnet
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Matos, Alexis Galeno
; Barbosa Neto, José de Paula
; Cavalcante, Carlos Philliph Pinheiro
; Andrade, Lucas Parente de
; Paula, Jayter Silva
.
ABSTRACT Capsulotomy with neodymium-doped yttrium--aluminum-garnet (Nd:YAG) laser is an effective treatment for posterior capsule opacification following cataract surgery. A wide opening of the posterior capsule associated with the ruptured anterior hyaloid can cause anterior chamber vitreous prolapse. Two patients who developed angle-closure glaucoma associated with vitreous prolapse following Nd:YAG laser posterior capsulotomy were successfully treated with antiglaucoma medication and peripheral iridotomies. Patient identification for potential risk factors and a careful postoperative follow-up are essential to avoid these serious complications. neodymiumdoped neodymium doped yttriumaluminumgarnet yttrium aluminum garnet NdYAG Nd YAG (Nd:YAG surgery angleclosure angle closure iridotomies followup follow up complications
2.
Angle-closure glaucoma associated with vitreous prolapse after neodymium-doped yttrium-aluminumgarnet laser posterior capsulotomy Angleclosure Angle closure neodymiumdoped neodymium doped yttriumaluminumgarnet yttrium aluminumgarnet
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Matos, Alexis Galeno
; Barbosa Neto, José de Paula
; Cavalcante, Carlos Philliph Pinheiro
; Andrade, Lucas Parente de
; Paula, Jayter Silva
.
ABSTRACT Capsulotomy with neodymium-doped yttriumaluminum-garnet (Nd:YAG) laser is an effective treatment for posterior capsule opacification following cataract surgery. A wide opening of the posterior capsule associated with the ruptured anterior hyaloid can cause anterior chamber vitreous prolapse. Two patients who developed angle-closure glaucoma associated with vitreous prolapse following Nd:YAG laser posterior capsulotomy were successfully treated with antiglaucoma medication and peripheral iridotomies. Patient identification for potential risk factors and a careful postoperative follow-up are essential to avoid these serious complications. neodymiumdoped neodymium doped yttriumaluminumgarnet yttriumaluminum garnet NdYAG Nd YAG (Nd:YAG surgery angleclosure angle closure iridotomies followup follow up complications
3.
Vaccination coverage, delay and loss to follow-up of the triple viral vaccine, in live births between 2017 and 2018 in Brazilian cities coverage followup follow up vaccine 201 20 2
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D’Agostini, Tatiana Lang
; Zambom, Fernanda Florencia Fregnan
; Moraes, José Cássio de
; França, Ana Paula
; Camargo, Jéssica Pires de
; Ribeiro, Manoel Carlos Sampaio de Almeida
; Barata, Rita Barradas
; Silva, Adriana Ilha da
; Ramos Jr., Alberto Novaes
; França, Ana Paula
; Oliveira, Andrea de Nazaré Marvão
; Boing, Antonio Fernando
; Domingues, Carla Magda Allan Santos
; Oliveira, Consuelo Silva de
; Maciel, Ethel Leonor Noia
; Guibu, Ione Aquemi
; Mirabal, Isabelle Ribeiro Barbosa
; Barbosa, Jaqueline Caracas
; Lima, Jaqueline Costa
; Moraes, José Cássio de
; Luhm, Karin Regina
; Caetano, Karlla Antonieta Amorim
; Lima, Luisa Helena de Oliveira
; Antunes, Maria Bernadete de Cerqueira
; Teixeira, Maria da Gloria
; Teixeira, Maria Denise de Castro
; Borges, Maria Fernanda de Sousa Oliveira
; Queiroz, Rejane Christine de Sousa
; Gurgel, Ricardo Queiroz
; Barata, Rita Barradas
; Azevedo, Roberta Nogueira Calandrini de
; Oliveira, Sandra Maria do Valle Leone de
; Teles, Sheila Araújo
; Gama, Silvana Granado Nogueira da
; Mengue, Sotero Serrate
; Simões, Taynãna César
; Nascimento, Valdir
; Araújo, Wildo Navegantes de
.
RESUMO Objetivo Estimar cobertura vacinal, atraso e perda de seguimento da vacina tríplice viral, em crianças até 24 meses residentes em cidades brasileiras. Método Inquérito domiciliar baseado em uma coorte retrospectiva de nascidos vivos em 2017-2018, que analisou cobertura e dados sociodemográficos das crianças e famílias, a partir dos registros da caderneta de vacinação e entrevista. Resultados A cobertura válida da primeira dose foi de 90,0% (IC95% 88,9;91,0), e da segunda, e 81,1% (IC95% 79,8;82,4). O atraso para ambas as doses foi de 23,2% (IC95% 21,9;24,5) e a perda de seguimento de 10,8% (IC95% 9,9;11,8). O estrato socioeconômico A apresentou menor cobertura e, à medida que a ordem de nascimento aumentava, menor era a cobertura para as duas doses. Crianças de mães com 13 a 15 anos de escolaridade apresentaram maior cobertura. Conclusão As coberturas não alcançaram a meta preconizada. Estratégias diferenciadas para dirimir dificuldade de acesso, desinformação e hesitação poderão melhorar a cobertura. vacinal viral 2 brasileiras 20172018, 20172018 2017 2018, 2018 2017-2018 famílias entrevista 900 90 0 90,0 IC95% IC95 IC (IC95 88,991,0, 889910 88,9 91,0 , 88 9 91 88,9;91,0) segunda 811 81 1 81,1 79,882,4. 798824 79,8 82,4 . 79 8 82 4 79,8;82,4) 232 23 23,2 21,924,5 219245 21,9 24,5 21 5 21,9;24,5 108 10 10,8 9,911,8. 99118 9,9 11,8 11 9,9;11,8) aumentava preconizada acesso 2017201 201 2017-201 90, IC9 (IC9 991 88,991,0 88991 889 88, 910 91, 88,9;91,0 81, 882 79,882,4 79882 798 79, 824 82, 7 79,8;82,4 23, 924 21,924, 21924 219 21, 245 24, 21,9;24, 10, 911 9,911,8 9911 99 9, 118 11, 9,9;11,8 201720 20 2017-20 (IC 88,991, 8899 88,9;91, 79,882, 7988 79,8;82, 92 21,924 2192 21,9;24 9,911, 9,9;11, 20172 2017-2 88,991 88,9;91 79,882 79,8;82 21,92 21,9;2 9,911 9,9;11 2017- 88,99 88,9;9 79,88 79,8;8 21,9; 9,91 9,9;1 88,9; 79,8; 9,9;
ABSTRACT Objective To estimate measles-mumps-rubella vaccination coverage, delay and loss to follow-up in children up to 24 months old living in Brazilian cities. Methods Surveys and questionnaires with a retrospective cohort of live births in 2017-2018, analyzing vaccination coverage and sociodemographic data of children and families, based on vaccination card records and interviews. Results Valid coverage of first dose was 90.0% (95%CI 88.9;91.0) and 81.1% for the second dose (95%CI 79.8;82.4). Delay for both doses was 23.2% (95%CI 21.9;24.5) and loss to follow-up was 10.8% (95%CI 9.9;11.8). Socioeconomic stratum A had the lowest vaccination coverage and the higher the child’s birth order, the lower the vaccination coverage for the second dose. Children whose mothers had 13 to 15 years of education had higher vaccination coverage. Conclusion Coverage did not meet the recommended target. Differentiated strategies to resolve difficulties in access, misinformation, and vaccination hesitancy will help improve vaccination coverage. measlesmumpsrubella measles mumps rubella followup follow 2 cities 20172018, 20172018 2017 2018, 2018 2017-2018 families interviews 900 90 0 90.0 95%CI 95CI CI 95 88.991.0 889910 88.9 91.0 88 9 91 88.9;91.0 811 81 1 81.1 79.882.4. 798824 79.8 82.4 . 79 8 82 4 79.8;82.4) 232 23 23.2 21.924.5 219245 21.9 24.5 21 5 21.9;24.5 108 10 10.8 9.911.8. 99118 9.9 11.8 11 9.9;11.8) childs child s order target access misinformation 2017201 201 2017-201 90. 991 88.991. 88991 889 88. 910 91. 88.9;91. 81. 882 79.882.4 79882 798 79. 824 82. 7 79.8;82.4 23. 924 21.924. 21924 219 21. 245 24. 21.9;24. 10. 911 9.911.8 9911 99 9. 118 11. 9.9;11.8 201720 20 2017-20 88.991 8899 88.9;91 79.882. 7988 79.8;82. 92 21.924 2192 21.9;24 9.911. 9.9;11. 20172 2017-2 88.99 88.9;9 79.882 79.8;82 21.92 21.9;2 9.911 9.9;11 2017- 88.9; 79.88 79.8;8 21.9; 9.91 9.9;1 79.8; 9.9;
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4.
Position paper of diagnosis and treatment of post-extubation laryngitis in children: a multidisciplinary expert-based opinion postextubation post extubation children expertbased expert based
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Pazinatto, Débora Bressan
; Maunsell, Rebecca
; Avelino, Melissa Ameloti Gomes
; Lubianca Neto, Jose Faibes
; Schweiger, Cláudia
; Caldas, Jamil Pedro de Siqueira
; Brandão, Marcelo Barciela
; Souza, Paula Pires de
; Peixoto, Fernanda Aparecida de Oliveira
; Ricachinevsky, Claudia Pires
; Silveira, Rita C.
; Andreolio, Cinara
; Miura, Carolina Sponchiado
; Volpe, Daniele da Silva Jordan
; Ferri, Walusa Assad Gonçalves
; Gavazzoni, Fabiano Bleggi
; João, Paulo Ramos David
; Possas, Silmara Aparecida
; Chone, Carlos Takahiro
.
Abstract Objectives To make recommendations on the diagnosis and treatment of post-extubation laryngitis (PEL) in children with or without other comorbidities. Methods A three-iterative modified Delphi method was applied. Specialists were recruited representing pediatric otolaryngologists, pediatric and neonatal intensivists. Questions and statements approached topics encompassing definition, diagnosis, endoscopic airway evaluation, risk factors, comorbidities, management, and follow-up. A consensus was defined as a supermajority >70%. Results Stridor was considered the most frequent symptom and airway endoscopy was recommended for definitive diagnosis. Gastroesophageal reflux and previous history of intubation were considered risk factors. Specific length of intubation did not achieve a consensus as a risk factor. Systemic corticosteroids should be part of the medical treatment and dexamethasone was the drug of choice. No consensus was achieved regarding dosage of corticosteroids, although endoscopic findings help defining dosage and length of treatment. Non-invasive ventilation, laryngeal rest, and use of comfort sedation scales were recommended. Indications for microlaryngoscopy and bronchoscopy under anesthesia were symptoms progression or failure to improve after the first 72-h of medical treatment post-extubation, after two failed extubations, and/or suspicion of severe lesions on flexible fiberoptic laryngoscopy. Conclusions Management of post-extubation laryngitis is challenging and can be facilitated by a multidisciplinary approach. Airway endoscopy is mandatory and impacts decision-making, although there is no consensus regarding dosage and length of treatment. postextubation post extubation PEL (PEL comorbidities threeiterative three iterative applied otolaryngologists intensivists definition evaluation factors management followup. followup follow up. up follow-up 70 >70% factor choice Noninvasive Non invasive ventilation rest 72h h 72 postextubation, extubation, extubations andor laryngoscopy approach decisionmaking, decisionmaking decision making, making decision-making 7 >70 >7 >
5.
The impact of a breast cancer diagnosis on marital outcomes and factors associated with divorce and separation
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Werutsky, Gustavo
; Lopes, Mahira
; Jesus, Rafaela Gomes de
; Gazola, Antonia Angeli
; Pellegrini, Rodrigo Azevedo
; Rebelatto, Taiane Francieli
; Freitas, Laura von Wallwitz
; Heck, Ana Paula
; Silva, Arthur Ferreira da
; Rodrigues, Matheus Füehr
; Gössling, Gustavo
; Giacomazzi, Juliana
; Rocha, Matheus Soares
; Rosa, Daniela Dornelles
; Barrios, Carlos Henrique
; Cronemberger, Eduardo Henrique
; Queiroz, Geraldo Silva
; Bines, José
; Simon, Sérgio Daniel
; Fay, Andre Poisl
.
Abstract Objective To analyze marital outcomes, divorce or separation, and its association with demographic, socioeconomic, and clinicopathological factors among breast cancer (BC) survivors after 2-years of diagnosis. Methods We performed a retrospective analysis of marital status at baseline and at years 1 and 2 of follow-up of women aged ≥ 18 years diagnosed with invasive BC participating in the AMAZONA III (GBECAM0115) study. The BC diagnosis occurred between January 2016 and March 2018 at 23 institutions in Brazil. Results Of the 2974 women enrolled in AMAZONA III, 599 were married or living under common law at baseline. Divorce or separation occurred in 35 (5.8%) patients at 2 years of follow-up. In the multivariate analysis, public health insurance coverage was associated with a higher risk of marital status change (8.25% vs. 2.79%, RR 3.09, 95% CI 1.39 - 7.03, p = 0.007). Women who underwent mastectomy, adenomastectomy or skin-sparing mastectomy were associated with a higher risk of divorce or separation (8.1% vs. 4.49%, RR 1.97, 95 CI 1.04 – 3.72, p = 0.0366) than those who underwent breast-conserving surgery. Conclusion Women covered by the public health system and those who underwent mastectomy, adenomastectomy or skin-sparing mastectomy were associated with a higher risk of divorce or separation. This evidence further supports the idea that long-term marital stability is associated with a complex interplay between socioeconomic conditions and stressors, such as BC diagnosis and treatment. ClinicalTrials Registration: NCT02663973. outcomes demographic (BC 2years followup follow up GBECAM0115 GBECAM (GBECAM0115 study 201 Brazil 297 59 3 5.8% 58 5 8 (5.8% followup. up. 8.25% 825 25 (8.25 vs 279 79 2.79% 309 09 3.09 139 39 1.3 703 7 03 7.03 0.007. 0007 0.007 . 0 007 0.007) skinsparing skin sparing 8.1% 81 (8.1 449 4 49 4.49% 197 97 1.97 9 104 04 1.0 372 72 3.72 0.0366 00366 0366 breastconserving conserving surgery longterm long term stressors treatment Registration NCT02663973 NCT GBECAM011 (GBECAM011 20 29 5.8 (5.8 8.25 82 (8.2 27 2.79 30 3.0 13 1. 70 7.0 000 0.00 00 8.1 (8. 44 4.49 19 1.9 10 37 3.7 0.036 0036 036 NCT0266397 GBECAM01 (GBECAM01 5. (5. 8.2 2.7 3. 7. 0.0 8. (8 4.4 0.03 003 NCT026639 GBECAM0 (GBECAM0 (5 2. 0. ( 4. NCT02663 (GBECAM NCT0266 NCT026 NCT02 NCT0
6.
ENAM gene polymorphisms associated with dental anomalies in individuals with cleft lip and palate
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Oliveira, Fernanda Veronese de
; Santos, Carlos Ferreira dos
; Dionísio, Thiago José
; Neves, Lucimara Teixeira das
; Dalben, Gisele da Silva
; Ambrosio, Eloá Cristina Passucci
; Jorge, Paula Karine
; Machado, Maria Aparecida Andrade Moreira
; Oliveira, Thais Marchini
.
Aim This study aimed to investigate the occurrence of enamelin gene (ENAM) single nucleotide polymorphisms (SNP) and ENAM polymorphism association with dental anomalies (DA) in individuals with unilateral or bilateral cleft lip and palate (CLP). Methods Saliva samples were collected from 147 individuals aged between 6 and 15 years-old, both genders, and divided into 4 groups: Group 1 (G1) - CLP and DA; Group 2 (G2) - CLP without DA; Group 3 (G3) - without CLP with DA; Group 4 (G4) - without CLP and DA. The genomic DNA was extracted from saliva samples and the following ENAM SNPs markers were genotyped: rs3796703, rs3796704, rs3796705, rs7671281, rs2609428, and rs35951442. Fisher exact and Pearson’s Chi-square tests statistically analyzed the results (α=5%). Results Individuals without CLP with DA (Group 3 - 19.2%) showed statistically higher prevalence of SNP rs2609428 heterozygotes (p=0.006) than individuals with CLP and DA (Group 1 - 0%). Individuals without CLP (10%) exhibited statistically higher prevalence of mutated heterozygotes/homozygous (p=0.028) than in individuals with CLP (1.3%). Conclusion SNP rs2609428 marker of ENAM gene may be associated with dental anomalies in individuals without cleft lip and palate. (ENAM (SNP (DA CLP. . (CLP) 14 yearsold, yearsold years old, old years-old genders groups G1 G (G1 G2 (G2 G3 (G3 G4 (G4 genotyped rs3796703 rs rs3796704 rs3796705 rs7671281 rs35951442 Pearsons Pearson s Chisquare Chi square α=5%. α5 α α=5% 5 (α=5%) 19.2% 192 19 rs260942 p=0.006 p0006 p 0 006 (p=0.006 0%. 0% 0%) 10% 10 (10% heterozygoteshomozygous homozygous p=0.028 p0028 028 (p=0.028 1.3%. 13 1.3% (1.3%) (CLP (G rs379670 rs767128 rs3595144 α=5 (α=5% 19.2 rs26094 p=0.00 p000 00 (p=0.00 (10 p=0.02 p002 02 (p=0.02 1.3 (1.3% rs37967 rs76712 rs359514 α= (α=5 19. rs2609 p=0.0 p00 (p=0.0 (1 1. (1.3 rs3796 rs7671 rs35951 (α= rs260 p=0. p0 (p=0. ( (1. rs379 rs767 rs3595 (α rs26 p=0 (p=0 rs37 rs76 rs359 rs2 p= (p= rs3 rs7 rs35 (p
7.
VATICAN (Ventilator-Associated Tracheobronchitis Initiative to Conduct Antibiotic Evaluation): protocol for a multicenter randomized open-label trial of watchful waiting versus antimicrobial therapy for ventilator-associated tracheobronchitis VentilatorAssociated Ventilator Associated Evaluation Evaluation) openlabel open label ventilatorassociated ventilator associated
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Tomazini, Bruno Martins
; Besen, Bruno Adler Maccagnan Pinheiro
; Dietrich, Camila
; Gandara, Ana Paula Rossi
; Silva, Debora Patrícia
; Pinheiro, Carla Cristina Gomes
; Luz, Mariane Nascimento
; Mattos, Renata Rodrigues de
; Reis, Luiz Fernando Lima
; Roepke, Roberta Muriel Longo
; Duarte, Carlos Sérgio Luna Gomes
; Nassar Júnior, Antônio Paulo
; Veiga, Viviane Cordeiro
; Arns, Beatriz
; Nascimento, Giovanna Marssola
; Pereira, Adriano José
; Cavalcanti, Alexandre Biasi
; Machado, Flávia Ribeiro
; Azevedo, Luciano Cesar Pontes
.
RESUMO Contexto A traqueobronquite associada ao ventilador é uma condição comum entre pacientes ventilados invasivamente em unidades de terapia intensiva, para a qual se desconhece atualmente a melhor estratégia de tratamento. Desenhamos o estudo VATICAN (Ventilator-Associated Tracheobronchitis Initiative to Conduct Antibiotic Evaluation) para avaliar se uma estratégia de tratamento antibiótico de espera vigilante não é inferior ao tratamento antibiótico de rotina para traqueobronquite associada ao ventilador em relação aos dias sem ventilador mecânico. Métodos O VATICAN é um estudo randomizado, controlado, aberto e multicêntrico de não inferioridade. Os pacientes com suspeita de traqueobronquite associada ao ventilador sem evidência de pneumonia associada ao ventilador ou instabilidade hemodinâmica devido a uma provável infecção serão designados para uma estratégia de espera vigilante, sem administração profilática de antimicrobianos contra traqueobronquite associada ao ventilador e prescrição de antimicrobianos somente em casos de pneumonia associada ao ventilador, sepse ou choque séptico, ou outro diagnóstico infeccioso, ou para uma estratégia de tratamento antimicrobiano de rotina por 7 dias. O desfecho primário será o número de dias sem ventilador mecânico em 28 dias, e um desfecho secundário importante será a sobrevida sem pneumonia associada ao ventilador. Por meio de uma estrutura de intenção de tratar com análise de sensibilidade por protocolo, a análise do desfecho primário abordará a não inferioridade com margem de 20%, o que se traduz em uma diferença de 1,5 dia sem ventilador. Outras análises seguirão uma estrutura de análise de superioridade. Conclusão O VATICAN seguirá todos os padrões éticos nacionais e internacionais. O objetivo é publicar o estudo em um periódico geral de alta visibilidade e apresentá-lo em conferências de cuidados intensivos e doenças infecciosas para divulgação. Estes resultados provavelmente serão imediatamente aplicáveis à beira do leito após a conclusão do estudo e fornecerão informações com baixo risco de viés para o desenvolvimento de diretrizes. intensiva VentilatorAssociated Ventilator Associated Evaluation randomizado controlado séptico infeccioso 2 protocolo 20 20% 15 1 5 1, superioridade internacionais apresentálo apresentá lo divulgação diretrizes
ABSTRACT Background Ventilator-associated tracheobronchitis is a common condition among invasively ventilated patients in intensive care units, for which the best treatment strategy is currently unknown. We designed the VATICAN (Ventilator-Associated Tracheobronchitis Initiative to Conduct Antibiotic Evaluation) trial to assess whether a watchful waiting antibiotic treatment strategy is noninferior to routine antibiotic treatment for ventilator-associated tracheobronchitis regarding days free of mechanical ventilation. Methods VATICAN is a randomized, controlled, open-label, multicenter noninferiority trial. Patients with suspected ventilator-associated tracheobronchitis without evidence of ventilator-associated pneumonia or hemodynamic instability due to probable infection will be assigned to either a watchful waiting strategy, without antimicrobial administration for ventilator-associated tracheobronchitis and prescription of antimicrobials only in cases of ventilator-associated pneumonia, sepsis or septic shock, or another infectious diagnosis, or to a routine antimicrobial treatment strategy for seven days. The primary outcome will be mechanical ventilation-free days at 28 days, and a key secondary outcome will be ventilator-associated pneumonia-free survival. Through an intention-to-treat framework with a per-protocol sensitivity analysis, the primary outcome analysis will address noninferiority with a 20% margin, which translates to a 1.5 difference in ventilator-free days. Other analyses will follow a superiority analysis framework. Conclusion The VATICAN trial will follow all national and international ethical standards. We aim to publish the trial in a high-visibility general journal and present it at critical care and infectious disease conferences for dissemination. These results will likely be immediately applicable to the bedside upon trial completion and will provide information with a low risk of bias for guideline development. Ventilatorassociated Ventilator associated units unknown VentilatorAssociated Associated Evaluation ventilatorassociated ventilator ventilation randomized controlled openlabel, openlabel open label, label open-label shock diagnosis ventilationfree 2 pneumoniafree survival intentiontotreat intention treat perprotocol per protocol 20 margin 15 1 5 1. ventilatorfree standards highvisibility high visibility dissemination development
8.
Catálogo Taxonômico da Fauna do Brasil: Setting the baseline knowledge on the animal diversity in Brazil Brasil
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Boeger, Walter A.
; Valim, Michel P.
; Zaher, Hussam
; Rafael, José A.
; Forzza, Rafaela C.
; Percequillo, Alexandre R.
; Serejo, Cristiana S.
; Garraffoni, André R.S.
; Santos, Adalberto J.
; Slipinski, Adam
; Linzmeier, Adelita M.
; Calor, Adolfo R.
; Garda, Adrian A.
; Kury, Adriano B.
; Fernandes, Agatha C.S.
; Agudo-Padrón, Aisur I.
; Akama, Alberto
; Silva Neto, Alberto M. da
; Burbano, Alejandro L.
; Menezes, Aleksandra
; Pereira-Colavite, Alessandre
; Anichtchenko, Alexander
; Lees, Alexander C.
; Bezerra, Alexandra M.R.
; Domahovski, Alexandre C.
; Pimenta, Alexandre D.
; Aleixo, Alexandre L.P.
; Marceniuk, Alexandre P.
; Paula, Alexandre S. de
; Somavilla, Alexandre
; Specht, Alexandre
; Camargo, Alexssandro
; Newton, Alfred F.
; Silva, Aline A.S. da
; Santos, Aline B. dos
; Tassi, Aline D.
; Aragão, Allan C.
; Santos, Allan P.M.
; Migotto, Alvaro E.
; Mendes, Amanda C.
; Cunha, Amanda
; Chagas Júnior, Amazonas
; Sousa, Ana A.T. de
; Pavan, Ana C.
; Almeida, Ana C.S.
; Peronti, Ana L.B.G.
; Henriques-Oliveira, Ana L.
; Prudente, Ana L.
; Tourinho, Ana L.
; Pes, Ana M.O.
; Carmignotto, Ana P.
; Wengrat, Ana P.G. da Silva
; Dornellas, Ana P.S.
; Molin, Anamaria Dal
; Puker, Anderson
; Morandini, André C.
; Ferreira, André da S.
; Martins, André L.
; Esteves, André M.
; Fernandes, André S.
; Roza, André S.
; Köhler, Andreas
; Paladini, Andressa
; Andrade, Andrey J. de
; Pinto, Ângelo P.
; Salles, Anna C. de A.
; Gondim, Anne I.
; Amaral, Antonia C.Z.
; Rondón, Antonio A.A.
; Brescovit, Antonio
; Lofego, Antônio C.
; Marques, Antonio C.
; Macedo, Antonio
; Andriolo, Artur
; Henriques, Augusto L.
; Ferreira Júnior, Augusto L.
; Lima, Aurino F. de
; Barros, Ávyla R. de A.
; Brito, Ayrton do R.
; Romera, Bárbara L.V.
; Vasconcelos, Beatriz M.C. de
; Frable, Benjamin W.
; Santos, Bernardo F.
; Ferraz, Bernardo R.
; Rosa, Brunno B.
; Sampaio, Brunno H.L.
; Bellini, Bruno C.
; Clarkson, Bruno
; Oliveira, Bruno G. de
; Corrêa, Caio C.D.
; Martins, Caleb C.
; Castro-Guedes, Camila F. de
; Souto, Camilla
; Bicho, Carla de L.
; Cunha, Carlo M.
; Barboza, Carlos A. de M.
; Lucena, Carlos A.S. de
; Barreto, Carlos
; Santana, Carlos D.C.M. de
; Agne, Carlos E.Q.
; Mielke, Carlos G.C.
; Caetano, Carlos H.S.
; Flechtmann, Carlos H.W.
; Lamas, Carlos J.E.
; Rocha, Carlos
; Mascarenhas, Carolina S.
; Margaría, Cecilia B.
; Waichert, Cecilia
; Digiani, Celina
; Haddad, Célio F.B.
; Azevedo, Celso O.
; Benetti, Cesar J.
; Santos, Charles M.D. dos
; Bartlett, Charles R.
; Bonvicino, Cibele
; Ribeiro-Costa, Cibele S.
; Santos, Cinthya S.G.
; Justino, Cíntia E.L.
; Canedo, Clarissa
; Bonecker, Claudia C.
; Santos, Cláudia P.
; Carvalho, Claudio J.B. de
; Gonçalves, Clayton C.
; Galvão, Cleber
; Costa, Cleide
; Oliveira, Cléo D.C. de
; Schwertner, Cristiano F.
; Andrade, Cristiano L.
; Pereira, Cristiano M.
; Sampaio, Cristiano
; Dias, Cristina de O.
; Lucena, Daercio A. de A.
; Manfio, Daiara
; Amorim, Dalton de S.
; Queiroz, Dalva L. de
; Queiroz, Dalva L. de
; Colpani, Daniara
; Abbate, Daniel
; Aquino, Daniel A.
; Burckhardt, Daniel
; Cavallari, Daniel C.
; Prado, Daniel de C. Schelesky
; Praciano, Daniel L.
; Basílio, Daniel S.
; Bená, Daniela de C.
; Toledo, Daniela G.P. de
; Takiya, Daniela M.
; Fernandes, Daniell R.R.
; Ament, Danilo C.
; Cordeiro, Danilo P.
; Silva, Darliane E.
; Pollock, Darren A.
; Muniz, David B.
; Gibson, David I.
; Nogueira, David S.
; Marques, Dayse W.A.
; Lucatelli, Débora
; Garcia, Deivys M.A.
; Baêta, Délio
; Ferreira, Denise N.M.
; Rueda-Ramírez, Diana
; Fachin, Diego A.
; Souza, Diego de S.
; Rodrigues, Diego F.
; Pádua, Diego G. de
; Barbosa, Diego N.
; Dolibaina, Diego R.
; Amaral, Diogo C.
; Chandler, Donald S.
; Maccagnan, Douglas H.B.
; Caron, Edilson
; Carvalho, Edrielly
; Adriano, Edson A.
; Abreu Júnior, Edson F. de
; Pereira, Edson H.L.
; Viegas, Eduarda F.G.
; Carneiro, Eduardo
; Colley, Eduardo
; Eizirik, Eduardo
; Santos, Eduardo F. dos
; Shimbori, Eduardo M.
; Suárez-Morales, Eduardo
; Arruda, Eliane P. de
; Chiquito, Elisandra A.
; Lima, Élison F.B.
; Castro, Elizeu B. de
; Orlandin, Elton
; Nascimento, Elynton A. do
; Razzolini, Emanuel
; Gama, Emanuel R.R.
; Araujo, Enilma M. de
; Nishiyama, Eric Y.
; Spiessberger, Erich L.
; Santos, Érika C.L. dos
; Contreras, Eugenia F.
; Galati, Eunice A.B.
; Oliveira Junior, Evaldo C. de
; Gallardo, Fabiana
; Hernandes, Fabio A.
; Lansac-Tôha, Fábio A.
; Pitombo, Fabio B.
; Dario, Fabio Di
; Santos, Fábio L. dos
; Mauro, Fabio
; Nascimento, Fabio O. do
; Olmos, Fabio
; Amaral, Fabio R.
; Schunck, Fabio
; Godoi, Fábio S. P. de
; Machado, Fabrizio M.
; Barbo, Fausto E.
; Agrain, Federico A.
; Ribeiro, Felipe B.
; Moreira, Felipe F.F.
; Barbosa, Felipe F.
; Silva, Fenanda S.
; Cavalcanti, Fernanda F.
; Straube, Fernando C.
; Carbayo, Fernando
; Carvalho Filho, Fernando
; Zanella, Fernando C.V.
; Jacinavicius, Fernando de C.
; Farache, Fernando H.A.
; Leivas, Fernando
; Dias, Fernando M.S.
; Mantellato, Fernando
; Vaz-de-Mello, Fernando Z.
; Gudin, Filipe M.
; Albuquerque, Flávio
; Molina, Flavio B.
; Passos, Flávio D.
; Shockley, Floyd W.
; Pinheiro, Francielly F.
; Mello, Francisco de A.G. de
; Nascimento, Francisco E. de L.
; Franco, Francisco L.
; Oliveira, Francisco L. de
; Melo, Francisco T. de V.
; Quijano, Freddy R.B.
; Salles, Frederico F.
; Biffi, Gabriel
; Queiroz, Gabriel C.
; Bizarro, Gabriel L.
; Hrycyna, Gabriela
; Leviski, Gabriela
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; Brown, George
; Mattox, George M.T.
; Zimbrão, Geraldo
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; Miranda, Gil F.G.
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; Lourido, Gilcélia M.
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; Moreira, Gilson R.P.
; Montingelli, Giovanna G.
; Maurício, Giovanni N.
; Marconato, Gláucia
; Lopez, Guilherme E.L.
; Silva, Guilherme L. da
; Muricy, Guilherme
; Brito, Guilherme R.R.
; Garbino, Guilherme S.T.
; Flores, Gustavo E.
; Graciolli, Gustavo
; Libardi, Gustavo S.
; Proctor, Heather C.
; Gil-Santana, Helcio R.
; Varella, Henrique R.
; Escalona, Hermes E.
; Schmitz, Hermes J.
; Rodrigues, Higor D.D.
; Galvão Filho, Hilton de C.
; Quintino, Hingrid Y.S.
; Pinto, Hudson A.
; Rainho, Hugo L.
; Miyahira, Igor C.
; Gonçalves, Igor de S.
; Martins, Inês X.
; Cardoso, Irene A.
; Oliveira, Ismael B. de
; Franz, Ismael
; Fernandes, Itanna O.
; Golfetti, Ivan F.
; S. Campos-Filho, Ivanklin
; Oliveira, Ivo de S.
; Delabie, Jacques H.C.
; Oliveira, Jader de
; Prando, Jadila S.
; Patton, James L.
; Bitencourt, Jamille de A.
; Silva, Janaina M.
; Santos, Jandir C.
; Arruda, Janine O.
; Valderrama, Jefferson S.
; Dalapicolla, Jeronymo
; Oliveira, Jéssica P.
; Hájek, Jiri
; Morselli, João P.
; Narita, João P.
; Martin, João P.I.
; Grazia, Jocélia
; McHugh, Joe
; Cherem, Jorge J.
; Farias Júnior, José A.S.
; Fernandes, Jose A.M.
; Pacheco, José F.
; Birindelli, José L.O.
; Rezende, José M.
; Avendaño, Jose M.
; Duarte, José M. Barbanti
; Ribeiro, José R. Inácio
; Mermudes, José R.M.
; Pujol-Luz, José R.
; Santos, Josenilson R. dos
; Câmara, Josenir T.
; Teixeira, Joyce A.
; Prado, Joyce R. do
; Botero, Juan P.
; Almeida, Julia C.
; Kohler, Julia
; Gonçalves, Julia P.
; Beneti, Julia S.
; Donahue, Julian P.
; Alvim, Juliana
; Almeida, Juliana C.
; Segadilha, Juliana L.
; Wingert, Juliana M.
; Barbosa, Julianna F.
; Ferrer, Juliano
; Santos, Juliano F. dos
; Kuabara, Kamila M.D.
; Nascimento, Karine B.
; Schoeninger, Karine
; Campião, Karla M.
; Soares, Karla
; Zilch, Kássia
; Barão, Kim R.
; Teixeira, Larissa
; Sousa, Laura D. do N.M. de
; Dumas, Leandro L.
; Vieira, Leandro M.
; Azevedo, Leonardo H.G.
; Carvalho, Leonardo S.
; Souza, Leonardo S. de
; Rocha, Leonardo S.G.
; Bernardi, Leopoldo F.O.
; Vieira, Letícia M.
; Johann, Liana
; Salvatierra, Lidianne
; Oliveira, Livia de M.
; Loureiro, Lourdes M.A. El-moor
; Barreto, Luana B.
; Barros, Luana M.
; Lecci, Lucas
; Camargos, Lucas M. de
; Lima, Lucas R.C.
; Almeida, Lucia M.
; Martins, Luciana R.
; Marinoni, Luciane
; Moura, Luciano de A.
; Lima, Luciano
; Naka, Luciano N.
; Miranda, Lucília S.
; Salik, Lucy M.
; Bezerra, Luis E.A.
; Silveira, Luis F.
; Campos, Luiz A.
; Castro, Luiz A.S. de
; Pinho, Luiz C.
; Silveira, Luiz F.L.
; Iniesta, Luiz F.M.
; Tencatt, Luiz F.C.
; Simone, Luiz R.L.
; Malabarba, Luiz R.
; Cruz, Luiza S. da
; Sekerka, Lukas
; Barros, Lurdiana D.
; Santos, Luziany Q.
; Skoracki, Maciej
; Correia, Maira A.
; Uchoa, Manoel A.
; Andrade, Manuella F.G.
; Hermes, Marcel G.
; Miranda, Marcel S.
; Araújo, Marcel S. de
; Monné, Marcela L.
; Labruna, Marcelo B.
; Santis, Marcelo D. de
; Duarte, Marcelo
; Knoff, Marcelo
; Nogueira, Marcelo
; Britto, Marcelo R. de
; Melo, Marcelo R.S. de
; Carvalho, Marcelo R. de
; Tavares, Marcelo T.
; Kitahara, Marcelo V.
; Justo, Marcia C.N.
; Botelho, Marcia J.C.
; Couri, Márcia S.
; Borges-Martins, Márcio
; Felix, Márcio
; Oliveira, Marcio L. de
; Bologna, Marco A.
; Gottschalk, Marco S.
; Tavares, Marcos D.S.
; Lhano, Marcos G.
; Bevilaqua, Marcus
; Santos, Marcus T.T.
; Domingues, Marcus V.
; Sallum, Maria A.M.
; Digiani, María C.
; Santarém, Maria C.A.
; Nascimento, Maria C. do
; Becerril, María de los A.M.
; Santos, Maria E.A. dos
; Passos, Maria I. da S. dos
; Felippe-Bauer, Maria L.
; Cherman, Mariana A.
; Terossi, Mariana
; Bartz, Marie L.C.
; Barbosa, Marina F. de C.
; Loeb, Marina V.
; Cohn-Haft, Mario
; Cupello, Mario
; Martins, Marlúcia B.
; Christofersen, Martin L.
; Bento, Matheus
; Rocha, Matheus dos S.
; Martins, Maurício L.
; Segura, Melissa O.
; Cardenas, Melissa Q.
; Duarte, Mércia E.
; Ivie, Michael A.
; Mincarone, Michael M.
; Borges, Michela
; Monné, Miguel A.
; Casagrande, Mirna M.
; Fernandez, Monica A.
; Piovesan, Mônica
; Menezes, Naércio A.
; Benaim, Natalia P.
; Reategui, Natália S.
; Pedro, Natan C.
; Pecly, Nathalia H.
; Ferreira Júnior, Nelson
; Silva Júnior, Nelson J. da
; Perioto, Nelson W.
; Hamada, Neusa
; Degallier, Nicolas
; Chao, Ning L.
; Ferla, Noeli J.
; Mielke, Olaf H.H.
; Evangelista, Olivia
; Shibatta, Oscar A.
; Oliveira, Otto M.P.
; Albornoz, Pablo C.L.
; Dellapé, Pablo M.
; Gonçalves, Pablo R.
; Shimabukuro, Paloma H.F.
; Grossi, Paschoal
; Rodrigues, Patrícia E. da S.
; Lima, Patricia O.V.
; Velazco, Paul
; Santos, Paula B. dos
; Araújo, Paula B.
; Silva, Paula K.R.
; Riccardi, Paula R.
; Garcia, Paulo C. de A.
; Passos, Paulo G.H.
; Corgosinho, Paulo H.C.
; Lucinda, Paulo
; Costa, Paulo M.S.
; Alves, Paulo P.
; Roth, Paulo R. de O.
; Coelho, Paulo R.S.
; Duarte, Paulo R.M.
; Carvalho, Pedro F. de
; Gnaspini, Pedro
; Souza-Dias, Pedro G.B.
; Linardi, Pedro M.
; Bartholomay, Pedro R.
; Demite, Peterson R.
; Bulirsch, Petr
; Boll, Piter K.
; Pereira, Rachel M.M.
; Silva, Rafael A.P.F.
; Moura, Rafael B. de
; Boldrini, Rafael
; Silva, Rafaela A. da
; Falaschi, Rafaela L.
; Cordeiro, Ralf T.S.
; Mello, Ramon J.C.L.
; Singer, Randal A.
; Querino, Ranyse B.
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; Constantino, Reginaldo
; Guedes, Reinaldo C.
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; Gomes, Renata S.
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; Kawada, Ricardo
; Dias, Ricardo M.
; Siewert, Ricardo
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; Leschen, Richard A.B.
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; Robbins, Robert
; Pinto, Roberta R.
; Reis, Roberto E. dos
; Ramos, Robson T. da C.
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; Caires, Rodrigo A.
; Salvador, Rodrigo B.
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; Araujo, Rodrigo de O.
; Dios, Rodrigo de V.P.
; Johnsson, Rodrigo
; Feitosa, Rodrigo M.
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; Lara, Rogéria I.R.
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; Hutchings, Rosa S.G.
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; Brito, Rosangela
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; Christo, Susete W.
; Cunha, Suzan B.Z.
; Gomes, Suzete R.
; Duarte, Tácio
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; Marques, Taísa
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; Sepulveda, Tatiana A.
; Maria, Tatiana F.
; Ruschel, Tatiana P.
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; Almeida, Thaís M. de
; Miranda, Thaís P.
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; Pacheco, Thaynara L.
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; Pikart, Tiago G.
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; Sousa, Viviane R.
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ABSTRACT The limited temporal completeness and taxonomic accuracy of species lists, made available in a traditional manner in scientific publications, has always represented a problem. These lists are invariably limited to a few taxonomic groups and do not represent up-to-date knowledge of all species and classifications. In this context, the Brazilian megadiverse fauna is no exception, and the Catálogo Taxonômico da Fauna do Brasil (CTFB) (http://fauna.jbrj.gov.br/), made public in 2015, represents a database on biodiversity anchored on a list of valid and expertly recognized scientific names of animals in Brazil. The CTFB is updated in near real time by a team of more than 800 specialists. By January 1, 2024, the CTFB compiled 133,691 nominal species, with 125,138 that were considered valid. Most of the valid species were arthropods (82.3%, with more than 102,000 species) and chordates (7.69%, with over 11,000 species). These taxa were followed by a cluster composed of Mollusca (3,567 species), Platyhelminthes (2,292 species), Annelida (1,833 species), and Nematoda (1,447 species). All remaining groups had less than 1,000 species reported in Brazil, with Cnidaria (831 species), Porifera (628 species), Rotifera (606 species), and Bryozoa (520 species) representing those with more than 500 species. Analysis of the CTFB database can facilitate and direct efforts towards the discovery of new species in Brazil, but it is also fundamental in providing the best available list of valid nominal species to users, including those in science, health, conservation efforts, and any initiative involving animals. The importance of the CTFB is evidenced by the elevated number of citations in the scientific literature in diverse areas of biology, law, anthropology, education, forensic science, and veterinary science, among others. publications problem uptodate up date classifications context exception (CTFB http//fauna.jbrj.gov.br/, httpfaunajbrjgovbr http //fauna.jbrj.gov.br/ , jbrj gov br (http://fauna.jbrj.gov.br/) 2015 Brazil 80 specialists 1 2024 133691 133 691 133,69 125138 125 138 125,13 82.3%, 823 82 3 (82.3% 102000 102 000 102,00 7.69%, 769 7 69 (7.69% 11000 11 11,00 . 3,567 3567 567 (3,56 2,292 2292 2 292 (2,29 1,833 1833 833 (1,83 1,447 1447 447 (1,44 1000 1,00 831 (83 628 (62 606 (60 520 (52 50 users science health biology law anthropology education others http//fauna.jbrj.gov.br/ faunajbrjgovbr //fauna.jbrj.gov.br (http://fauna.jbrj.gov.br/ 201 8 202 13369 13 133,6 12513 12 125,1 82.3% (82.3 10200 10 00 102,0 7.69% 76 6 (7.69 1100 11,0 3,56 356 56 (3,5 2,29 229 29 (2,2 1,83 183 83 (1,8 1,44 144 44 (1,4 100 1,0 (8 62 (6 60 52 (5 5 http//fauna.jbrj.gov.br (http://fauna.jbrj.gov.br 20 1336 133, 1251 125, 82.3 (82. 1020 0 102, 7.69 (7.6 110 11, 3,5 35 (3, 2,2 22 (2, 1,8 18 (1, 1,4 14 4 ( 82. (82 7.6 (7. 3, (3 2, (2 (1 7. (7
9.
Effect of Fiberglass Post Technique Removal on the Root Dentin Loss, the Root Canal Alignment and the Root Perforation Occurrence Loss
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Gomes, Marcio Alex Barros
; Moura, Camilla Christian Gomes
; Capeletti, Lucas Raineri
; Chaves, Gustavo Silva
; Decurcio, Daniel de Almeida
; Rodrigues, Monise de Paula
; Soares, Carlos José
.
Resumo O retratamento do canal radicular e a fratura de pinos de fibra de vidro (FGP) podem exigir a remoção de FGPs. O objetivo deste estudo foi avaliar a influência das técnicas de remoção de FGP no tempo de remoção de FGP (min), no volume de dentina radicular removida (mm3), na alteração do ângulo do alinhamento do canal radicular (o) e na ocorrência de perfuração radicular usando análise de tomografia computadorizada de feixe cônico (CBCT). Trinta molares superiores extraídos foram divididos aleatoriamente em 3 grupos: Mic-Ult, FGP removido usando insertos ultrassônicos sob ampliação microscópica; Mic-DiB, FGP removido usando pontas de diamante sob ampliação microscópica, e Endo-G, FGP removido usando guia prototipado. Os CBCTs foram feitos após a abertura do acesso e após a remoção do FGP. O volume de dentina radicular, o alinhamento do canal radicular e a perfuração radicular foram realizados com os softwares InVesalius e Mimics. A alteração do ângulo do canal radicular após a remoção do FGP foi realizada usando o software ImageJ. O tempo para remoção do FGP foi calculado em min. Os dados foram analisados por análise de variância unidirecional seguida pelo teste Tukey HSD (α = 0,05). Endo-G resultou em significativamente menor remoção de dentina radicular (p< 0,001) e significativamente menor tempo para o procedimento do que Mic-Ult e Mic-DiB (p< 0,001). Mic-DiB resultou em 1 e Mic-Ult em 2 perfurações de dentina radicular. A remoção do pino FGP usando Mic-Ult e Mic-DiB exibiu alteração significativamente maior no alinhamento do canal radicular do que usando Endo-G (p<0,001). A remoção de FGP usando Endo-G resultou em maior preservação do alinhamento do canal original, preservou a estrutura da dentina radicular e exigiu menor tempo em comparação com a remoção de FGP usando Mic-DiB ou Mic-Ult sob ampliação microscópica. (FGP FGPs min, min , (min) mm3, mm3 mm (mm3) (o CBCT. CBCT . (CBCT) grupos MicUlt, MicUlt Mic Ult, Ult microscópica MicDiB, MicDiB DiB, DiB EndoG, EndoG Endo G, G prototipado Mimics ImageJ α 0,05. 005 0,05 0 05 0,05) p< p (p 0,001 0001 001 0,001. p<0,001. p0001 p<0,001 (p<0,001) original (min (mm3 (CBCT 00 0,0 0,00 000 p000 p<0,00 (p<0,001 (mm 0, p00 p<0,0 (p<0,00 p0 p<0, (p<0,0 p<0 (p<0, (p<0
Abstract Root canal retreatment and fracture of fiberglass posts (FGP) can require the FGP removal. The aim of this study was to evaluate the effect of the FGP removal protocol on the time for FGP removal (min), the root dentin removed (mm3), the angle alteration of the root canal alignment (o), and the root perforation occurrence using cone-beam computed tomography (CBCT) analysis. Thirty extracted maxillary molars were randomly assigned to 3 groups (n = 10): Mic-Ult, FGP removed using ultrasonic inserts under microscopic magnification; Mic-DiB, FGP removed using diamond burs under microscopic magnification, and Endo-G, FGP removed using Endo-G. CBCTs were made after access opening and after FGP removal. The volume of root dentin, the root canal alignment and root perforation were performed using InVesalius and Mimics softwares. Root canal angle alteration after FGP removal was performed using ImageJ software. The time for FGP removal was calculated in min. Data were analysed by one-way analysis of variance was followed by Tukey HSD test (α = 0.05). Endo-G resulted in significantly lower root dentin removal (p< .001), and significantly less time than Mic-Ult and Mic-DiB (p< .001). Mic-DiB had 1 and Mic-Ult had 2 root dentin perforations. FGP post removal using Mic-Ult and Mic-DiB exhibited significantly greater alteration in the root canal alignment than that using Endo-G (p< .001). FGP removal using Endo-G exhibited better preservation of the original canal alignment, saved root dentin structure, and also required less time compared to FGP post removal using Mic-DiB or Mic-Ult under microscopic magnification. (FGP min, min , (min) mm3, mm3 mm (mm3) o, o (o) conebeam cone beam CBCT (CBCT n 10 10) MicUlt, MicUlt Mic Ult, Ult magnification MicDiB, MicDiB DiB, DiB EndoG, EndoG Endo G, G EndoG. G. softwares software oneway one way α 0.05. 005 0.05 . 0 05 0.05) p< p (p .001, 001 .001 .001) .001. perforations structure (min (mm3 (o 00 0.0 .00 (mm 0. .0
10.
Effectiveness and Safety of Direct-Acting Antivirals in the Treatment of Chronic Hepatitis C: A Real-life Study in Northeastern Brazil DirectActing Direct Acting C Reallife Real life
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Hyppolito, Elodie Bomfim
; Ramos Jr, Alberto Novaes
; Teixeira, Larissa Peixoto
; Bezerra, Arthur Machado
; Mendes, Lucas Arruda
; Silva, Taynara Lais
; Lima, José Milton de Castro
; Arruda, Érico Antonio Gomes de
; Guerra, Eder Janes
; Tavares, Maria Macedo Saraiva
; Lima, Carlos Eduardo Pereira
; Esmeraldo, Ticiana Mota
; Pessoa, Francisco Sérgio Rangel de Paula
; Pierre, Alessandra Maria Montalverne
; Pereira, Karla Brandão
; Araújo Filho, Antônio Haroldo
; Linhares, Lívia Melo Carone
; Ferreira, Anderson Fuentes
; Pires Neto, Roberto da Justa
.
Revista da Sociedade Brasileira de Medicina Tropical
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ABSTRACT Background: This study aimed to evaluate the effectiveness and safety of direct-acting antivirals (DAAs) for hepatitis C treatment by measuring sustained virologic response (SVR) and serious adverse events to help design effective interventions for reducing disease prevalence. Methods: This was a retrospective, observational, real-life study of patients with chronic hepatitis C receiving DAA treatment in the state of Ceará, Brazil. Data were collected in REDCap and analyzed using R® software by the Student's t, chi-square, and Fisher’s exact tests, with a significance level of 5%. Results: In this study, 1075 patients who were diagnosed with hepatitis C infection between October 2015 and October 2023 were included. The mean age of the participants was 56.6 ± 11 years and 60.2% were men. The sample included 51 HIV-infected patients (6.6%), 166 (15,4%) liver transplant recipients, 34 (3,1%) kidney transplant recipients, and 446 patients with cirrhosis (41.4%). The overall SVR rate was 96.4%. The sofosbuvir/daclatasvir/ribavirin regimen used in 354 (32.9%) patients achieved an SVR of 96%. The cure rate was 96.5%, with a lower SVR in patients with cirrhosis (93.4%) than in those with less severe fibrosis (97.9%) (p=0.0015). Serious adverse events associated with ribavirin use occurred in 3.5% of patients. Conclusions: DAA treatment for hepatitis C achieved SVR in real life in all patient profiles, including transplant recipients, HIV carriers, and patients with cirrhosis. Although these drugs are safe, a few decompensated patients with cirrhosis died during treatment. Background directacting direct acting DAAs (DAAs (SVR prevalence Methods retrospective observational reallife Ceará Brazil R Students Student s t chisquare, chisquare chi square, square chi-square Fishers Fisher tests 5 5% Results 107 201 202 566 56 6 56. 1 602 60 2 60.2 men HIVinfected infected 6.6%, 66 6.6% , (6.6%) 16 15,4% 154 15 4 (15,4% recipients 3 3,1% 31 (3,1% 44 41.4%. 414 41.4% . 41 (41.4%) 964 96 96.4% sofosbuvirdaclatasvirribavirin sofosbuvir daclatasvir 35 32.9% 329 32 9 (32.9% 96% 965 96.5% 93.4% 934 93 (93.4% 97.9% 979 97 (97.9% p=0.0015. p00015 p p=0.0015 0 0015 (p=0.0015) 3.5 Conclusions profiles carriers safe 10 20 60. 6.6 (6.6% 15,4 (15,4 3,1 (3,1 41.4 (41.4% 96.4 32.9 (32.9 96.5 93.4 (93.4 97.9 (97.9 p0001 p=0.001 001 (p=0.0015 3. 6. (6.6 15, (15, 3, (3, 41. (41.4 96. 32. (32. 93. (93. 97. (97. p000 p=0.00 00 (p=0.001 (6. (15 (3 (41. (32 (93 (97 p00 p=0.0 (p=0.00 (6 (1 ( (41 (9 p0 p=0. (p=0.0 (4 p=0 (p=0. p= (p=0 (p= (p
11.
Analysis of polio vaccination status in a cohort of live births in 2017 and 2018 in Brazilian cities: a national vaccination coverage survey 201 cities 20 2
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Franco, Alessandra Lucchesi de Menezes Xavier
; França, Ana Paula
; Moraes, José Cássio de
; Ribeiro, Manoel Carlos Sampaio de Almeida
; Silva, Adriana Ilha da
; Ramos Jr., Alberto Novaes
; França, Ana Paula
; Oliveira, Andrea de Nazaré Marvão
; Boing, Antonio Fernando
; Domingues, Carla Magda Allan Santos
; Oliveira, Consuelo Silva de
; Maciel, Ethel Leonor Noia
; Guibu, Ione Aquemi
; Mirabal, Isabelle Ribeiro Barbosa
; Barbosa, Jaqueline Caracas
; Lima, Jaqueline Costa
; Moraes, José Cássio de
; Luhm, Karin Regina
; Caetano, Karlla Antonieta Amorim
; Lima, Luisa Helena de Oliveira
; Antunes, Maria Bernadete de Cerqueira
; Teixeira, Maria da Gloria
; Teixeira, Maria Denise de Castro
; Borges, Maria Fernanda de Sousa Oliveira
; Queiroz, Rejane Christine de Sousa
; Gurgel, Ricardo Queiroz
; Barata, Rita Barradas
; Azevedo, Roberta Nogueira Calandrini de
; Oliveira, Sandra Maria do Valle Leone de
; Teles, Sheila Araújo
; Gama, Silvana Granado Nogueira da
; Mengue, Sotero Serrate
; Simões, Taynãna César
; Nascimento, Valdir
; Araújo, Wildo Navegantes de
.
RESUMO Objetivo Descrever a situação vacinal contra poliomielite em 26 capitais, Distrito Federal e 12 municípios do Brasil, em crianças nascidas em 2017 e 2018. Métodos Inquérito domiciliar de base populacional realizado de 2020 a 2022, em que se avaliou a cobertura vacinal da poliomielite em crianças, considerando doses válidas, aplicadas e oportunas por municípios. Resultados Foram coletados dados de 37.801 crianças. A cobertura vacinal de esquema completo de doses válidas foi de 87,5% (IC95% 86,2;88,7), caindo para 79,6% (IC95% 78,1;81,0), considerando a dose de reforço. A taxa de abandono foi de 4,5% para esquema completo, e de 11,7% no primeiro reforço. Não houve correlação entre a realização de campanha e as elevadas coberturas. Conclusão A cobertura vacinal de esquema completo e no primeiro reforço não atingiu a meta de 95,0%. Diferenças regionais e a associação das coberturas vacinais com indicadores sociais devem ser consideradas nas estratégias de aumento da cobertura. 2 capitais 1 Brasil 201 2018 202 2022 37801 37 801 37.80 875 87 5 87,5 IC95% IC95 IC (IC95 86,288,7, 862887 86,2 88,7 , 86 88 7 86,2;88,7) 796 79 6 79,6 78,181,0, 781810 78,1 81,0 78 81 0 78,1;81,0) 45 4 4,5 117 11 11,7 950 95 95,0% 20 3780 3 80 37.8 8 87, IC9 (IC9 288 86,288,7 86288 862 86, 887 88, 86,2;88,7 79, 181 78,181,0 78181 781 78, 810 81, 78,1;81,0 4, 11, 9 95,0 378 37. (IC 28 86,288, 8628 86,2;88, 18 78,181, 7818 78,1;81, 95, 86,288 86,2;88 78,181 78,1;81 86,28 86,2;8 78,18 78,1;8 86,2; 78,1;
ABSTRACT Objective To describe the polio vaccination status in 26 state capitals, the Federal District, and 12 municipalities in Brazil, among children born between 2017 and 2018. Methods This was a population-based household survey conducted from 2020 to 2022, which assessed polio vaccination coverage in children, considering valid, administered, and timely doses by municipality. Results Data were collected from 37,801 children. Vaccination coverage for the complete valid dose schedule was 87.5% (95%CI 86.2;88.7), dropping to 79.6% (95%CI 78.1;81.0), when the booster dose was considered. The dropout rate was 4.5% for the complete schedule, and 11.7% for the first booster. There was no correlation between campaign implementation and high coverage. Conclusion Vaccination coverage for the complete valid dose schedule and the first booster did not meet the 95.0% target. Regional disparities and the association between vaccination coverage and social indicators should be taken into consideration in strategies to increase coverage. 2 capitals District 1 Brazil 201 2018 populationbased population based 202 2022 administered municipality 37801 37 801 37,80 875 87 5 87.5 95%CI 95CI CI 95 86.288.7, 862887 86.2 88.7 , 86 88 7 86.2;88.7) 796 79 6 79.6 78.181.0, 781810 78.1 81.0 78 81 0 78.1;81.0) considered 45 4 4.5 117 11 11.7 950 95.0 target 20 3780 3 80 37,8 8 87. 9 288 86.288.7 86288 862 86. 887 88. 86.2;88.7 79. 181 78.181.0 78181 781 78. 810 81. 78.1;81.0 4. 11. 95. 378 37, 28 86.288. 8628 86.2;88. 18 78.181. 7818 78.1;81. 86.288 86.2;88 78.181 78.1;81 86.28 86.2;8 78.18 78.1;8 86.2; 78.1;
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12.
The II Brazilian Guidelines for the pharmacological treatment of patients hospitalized with COVID-19 Joint Guidelines of the Associação Brasileira de Medicina de Emergência, Associação de Medicina Intensiva Brasileira, Associação Médica Brasileira, Sociedade Brasileira de Angiologia e Cirurgia Vascular, Sociedade Brasileira de Infectologia, Sociedade Brasileira de Pneumologia e Tisiologia and Sociedade Brasileira de Reumatologia COVID19 COVID 19 COVID-1 Emergência Vascular Infectologia COVID1 1 COVID-
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Falavigna, Maicon
; Araujo, Cintia Laura Pereira de
; Barbosa, Alexandre Naime
; Belli, Karlyse Claudino
; Colpani, Verônica
; Dal-Pizzol, Felipe
; Silva, Rosemeri Maurici da
; Azevedo, Luciano César Pontes de
; Dias, Maria Beatriz Souza
; Amaral, José Luiz Gomes do
; Dorneles, Gilson Pires
; Ferreira, Juliana Carvalho
; Freitas, Ana Paula da Rocha
; Gräf, Débora Dalmas
; Guimarães, Hélio Penna
; Lobo, Suzana Margareth Ajeje
; Machado, Flávia Ribeiro
; Nunes, Michelle Silva
; Oliveira, Maura Salaroli de
; Parahiba, Suena Medeiros
; Rosa, Regis Goulart
; Santos, Vania Cristina Canuto
; Sobreira, Marcone Lima
; Veiga, Viviane Cordeiro
; Xavier, Ricardo Machado
; Zavascki, Alexandre Prehn
; Stein, Cinara
; Carvalho, Carlos Roberto Ribeiro de
.
RESUMO Objetivo: Atualizar as recomendações para embasar as decisões para o tratamento farmacológico de pacientes hospitalizados com COVID-19 no Brasil. Métodos: A elaboração desta diretriz foi feita por especialistas, incluindo representantes do Ministério da Saúde e metodologistas. O método utilizado para o desenvolvimento rápido de diretrizes baseou-se na adoção e/ou adaptação de diretrizes internacionais existentes (GRADE ADOLOPMENT) e contou com o apoio da plataforma e-COVID-19 RecMap. A qualidade das evidências e a elaboração das recomendações seguiram o método GRADE. Resultados: Chegaram-se a 21 recomendações, incluindo recomendações fortes quanto ao uso de corticosteroides em pacientes em uso de oxigênio suplementar e recomendações condicionais para o uso de tocilizumabe e baricitinibe, em pacientes com oxigênio suplementar ou ventilação não invasiva, e de anticoagulantes, para prevenção de tromboembolismo. Devido à suspensão da autorização de uso, não foi possível fazer recomendações para o tratamento com casirivimabe + imdevimabe. Foram feitas recomendações fortes contra o uso de azitromicina em pacientes sem suspeita de infecção bacteriana, hidroxicloroquina, plasma convalescente, colchicina e lopinavir + ritonavir, além de recomendações condicionais contra o uso de ivermectina e rendesivir. Conclusão: Foram criadas novas recomendações para o tratamento de pacientes hospitalizados com COVID-19, como as recomendações de tocilizumabe e baricitinibe. Ainda são recomendados corticosteroides e profilaxia contra tromboembolismo, esta em caráter condicional. Vários medicamentos foram considerados ineficazes e não devem ser usados, no intuito de proporcionar o melhor tratamento segundo os princípios da medicina baseada em evidências e promover a economia de recursos. Objetivo COVID19 COVID 19 COVID-1 Brasil Métodos especialistas metodologistas baseouse baseou se eou GRADE ADOLOPMENT eCOVID19 eCOVID e-COVID-1 RecMap Resultados Chegaramse Chegaram 2 baricitinibe invasiva anticoagulantes tromboembolismo imdevimabe bacteriana hidroxicloroquina convalescente ritonavir rendesivir Conclusão COVID19, 19, condicional usados recursos COVID1 1 COVID- eCOVID1 e-COVID- e-COVID
ABSTRACT Objective: To update the recommendations to support decisions regarding the pharmacological treatment of patients hospitalized with COVID-19 in Brazil. Methods: Experts, including representatives of the Ministry of Health and methodologists, created this guideline. The method used for the rapid development of guidelines was based on the adoption and/or adaptation of existing international guidelines (GRADE ADOLOPMENT) and supported by the e-COVID-19 RecMap platform. The quality of the evidence and the preparation of the recommendations followed the GRADE method. Results: Twenty-one recommendations were generated, including strong recommendations for the use of corticosteroids in patients using supplemental oxygen and conditional recommendations for the use of tocilizumab and baricitinib for patients on supplemental oxygen or on noninvasive ventilation and anticoagulants to prevent thromboembolism. Due to suspension of use authorization, it was not possible to make recommendations regarding the use of casirivimab + imdevimab. Strong recommendations against the use of azithromycin in patients without suspected bacterial infection, hydroxychloroquine, convalescent plasma, colchicine, and lopinavir + ritonavir and conditional recommendations against the use of ivermectin and remdesivir were made. Conclusion: New recommendations for the treatment of hospitalized patients with COVID-19 were generated, such as those for tocilizumab and baricitinib. Corticosteroids and prophylaxis for thromboembolism are still recommended, the latter with conditional recommendation. Several drugs were considered ineffective and should not be used to provide the best treatment according to the principles of evidence-based medicine and to promote resource economy. Objective COVID19 COVID 19 COVID-1 Brazil Methods Experts methodologists guideline andor ADOLOPMENT eCOVID19 eCOVID e e-COVID-1 platform Results Twentyone Twenty one generated authorization imdevimab infection hydroxychloroquine plasma colchicine made Conclusion recommended recommendation evidencebased economy COVID1 1 COVID- eCOVID1 e-COVID- e-COVID
13.
HERBase: A collection of understorey herb vegetation plots from Amazonia HERBase
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ANDRÉ, Thiago
; MOULATLET, Gabriel Massaine
; ALMEIDA, Thaís Elias
; ALVERGA, Paula Palhares de Polari
; BOELTER, Carlos Renato
; DRUCKER, Debora Pignatari
; SILVA, Julia Gomes da
; LINARES-PALOMINO, Reynaldo
; LOPES, Maria Aparecida
; MAGALHÃES, José Leonardo Lima
; MANZATTO, Angelo Gilberto
; MEWS, Henrique Augusto
; MOLL, Iracema Elizabeth de Siuza
; MORTATI, Amanda Frederico
; PAIXÃO, Eliana Celestino da
; QUINTERO-VALLEJO, Estela
; ANDEL, Tinde van
; SILVEIRA, Marcos
; STORCK-TONON, Danielle
; TUOMISTO, Hanna
; ZUQUIM, Gabriela
; COSTA, Flávia Regina Cappelloto
.
RESUMO As ervas do sub-bosque formam um componente diversificado e pouco estudado em florestas tropicais. Embora vários estudos e grupos de pesquisa tenham se dedicado ao estudo desse componente conspícuo na Amazônia, nenhum esforço foi feito até o momento para unificar essas informações. Em contraste com árvores e outros grupos de plantas para os quais já existem grandes compilações de dados, uma base de dados unificada dedicada às ervas ainda não existe. Parte do problema está em definir o que é uma erva e como amostrar comunidados de ervas de forma eficiente. Neste artigo descrevemos a base de dados HERBase, uma compilação exaustiva de dados publicados e não publicados sobre inventários de ervas na Amazônia. Também descrevemos a estrutura, funcionamento e diretrizes para curadoria e integração de dados na HERBase. Conseguimos compilar informações de 1381 parcelas de todas as seis regiões geográficas amazônicas. Com base nesses dados, descrevemos e discutimos lacunas de amostragem e conhecimento, apontamos áreas prioritárias para novas coletas e recomendamos protocolos de amostragem para facilitar a integração de dados no futuro. Essa nova base de dados fornece dados únicos de biodiversidade sobre ervas do sub-bosque que permitirão novos estudos sobre ecologia e biogeografia de comunidades. subbosque sub bosque tropicais Amazônia existe eficiente HERBase estrutura 138 amazônicas conhecimento futuro comunidades 13 1
ABSTRACT Understorey herbs form a diverse and understudied plant assemblage in tropical forests. Although several studies and research teams have long been dedicated to the study of this conspicuous vegetation component in Amazonia, no effort to unify the data has been undertaken to date. In contrast to trees and other life forms for which major data compilations already exist, a unified database dedicated to herbs is still lacking. Part of the problem is in defining what is a herb and how to effectively sample herb assemblages. In this article, we describe the database HERBase, an exhaustive compilation of published and unpublished data on herb inventories in Amazonia. We also describe the structure, functioning, and guidelines for data curation and integration in HERBase. We were able to compile information from 1381 plots from all six Amazonian geographic regions. Based on this dataset, we describe and discuss sampling and knowledge gaps, priority areas for new collections, and recommend sampling protocols to facilitate data integration in the future. This novel database provides a unique biodiversity data repository on understorey herbs that will enable new studies on community ecology and biogeography. forests Amazonia date exist lacking assemblages article HERBase structure functioning 138 regions dataset gaps collections future biogeography 13 1
14.
The SISBIOTA-Diptera Brazilian Network: A long-term survey of Diptera from unexplored Brazilian Western Arc of Amazon, Cerrado, and Pantanal SISBIOTADiptera SISBIOTA Network longterm long term Amazon Cerrado
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Lamas, Carlos José Einicker
; Fachin, Diego Aguilar
; Falaschi, Rafaela Lopes
; Alcantara, Daniel Máximo Correa de
; Ale-Rocha, Rosaly
; Amorim, Dalton de Souza
; Araújo, Maíra Xavier
; Ascendino, Sharlene
; Baldassio, Letícia
; Bellodi, Carolina Ferraz
; Bravo, Freddy
; Calhau, Julia
; Capellari, Renato Soares
; Carmo-Neto, Antonio Marcelino do
; Cegolin, Bianca Melo
; Couri, Márcia Souto
; Carvalho, Claudio José Barros de
; Dios, Rodrigo de Vilhena Perez
; Falcon, Aida Vanessa Gomez
; Fusari, Livia Maria
; Garcia, Carolina de Almeida
; Gil-Azevedo, Leonardo Henrique
; Gomes, Marina Morim
; Graciolli, Gustavo
; Gudin, Filipe Macedo
; Henriques, Augusto Loureiro
; Krolow, Tiago Kütter
; Mendes, Luanna Layla
; Limeira-de-Oliveira, Francisco
; Maia, Valéria Cid
; Marinoni, Luciane
; Mello, Ramon Luciano
; Mello-Patiu, Cátia Antunes de
; Morales, Mírian Nunes
; Oliveira, Sarah Siqueira
; Patiu, Claudemir
; Proença, Barbara
; Pujol-Luz, Cristiane Vieira de Assis
; Pujol-Luz, José Roberto
; Rafael, José Albertino
; Riccardi, Paula Raile
; Rodrigues, João Paulo Vinicios
; Roque, Fabio de Oliveira
; Sallum, Maria Anice Mureb
; Santis, Marcelo Domingos de
; Santos, Charles Morphy Dias dos
; Santos, Josenilson Rodrigues dos
; Savaris, Marcoandre
; Shimabukuro, Paloma Helena Fernandes
; Silva, Vera Cristina
; Schelesky-Prado, Daniel de Castro
; Silva-Neto, Alberto Moreira da
; Camargo, Alexssandro
; Sousa, Viviane Rodrigues de
; Urso-Guimarães, Maria Virginia
; Wiedenbrug, Sofia
; Yamaguchi, Carolina
; Nihei, Silvio Shigueo
.
ABSTRACT The SISBIOTA-BRASIL was a three-year multimillion-dollar research program of the Brazilian government to document plants and animals in endangered/understudied areas and biomes in Brazil. Distributional patterns and the historical events that generated them are extensively unknown regarding Brazilian fauna and flora. This deficiency hinders the development of conservation policies and the understanding of evolutionary processes. Conservation decisions depend on precise knowledge of the taxonomy and geographic distribution of species. Given such a premise, we proposed to research the diversity of Diptera of the Brazilian western arc of Amazon, Cerrado, and Pantanal in the states of Mato Grosso, Mato Grosso do Sul, and Rondônia. Three important biomes of the South American continent characterize these Brazilian states: Amazon forest, Cerrado (Brazilian Savannah), and Pantanal. Besides their ecological relevance, these biomes historically lack intensive entomological surveys. Therefore, they are much underrepresented in the Brazilian natural history collections and in the scientific literature, which is further aggravated by the fact that these areas are being exponentially and rapidly converted to commercial lands. Our project involved over 90 collaborators from 24 different Brazilian institutions and one from Colombia among researchers, postdocs, graduate and undergraduate students, and technicians. We processed and analyzed nearly 300,000 specimens from ~60 families of Diptera collected with a large variety of methods in the sampled areas. Here, we provide a detailed overview of the genera and species diversity of 41 families treated. Our results point to a total of 2,130 species and 514 genera compiled and identified for the three states altogether, with an increase of 41% and 29% in the numbers of species and genera known for the three states combined, respectively. Overall, the 10 most species-rich families were Tachinidae, Cecidomyiidae, Tabanidae, Psychodidae, Sarcophagidae, Stratiomyidae, Bombyliidae, Syrphidae, Tephritidae, and Asilidae. The 10 most diverse in the number of genera were Tachinidae, Stratiomyidae, Asilidae, Mycetophilidae, Syrphidae, Tabanidae, Muscidae, Dolichopodidae, Sarcophagidae, and Chloropidae. So far, 111 scientific papers were published regarding taxonomic, phylogenetic, and biogeographical aspects of the studied families, with the description of 101 new species and three new genera. We expect that additional publications will result from this investigation because several specimens are now curated and being researched by specialists. SISBIOTABRASIL SISBIOTA BRASIL threeyear year multimilliondollar multimillion dollar endangeredunderstudied endangered understudied Brazil flora processes premise Sul Rondônia forest Savannah, Savannah , Savannah) relevance surveys Therefore literature lands 9 2 researchers postdocs students technicians 300000 300 000 300,00 60 ~6 Here 4 treated 2130 130 2,13 51 altogether 29 combined respectively Overall 1 speciesrich rich Tachinidae Cecidomyiidae Tabanidae Psychodidae Sarcophagidae Stratiomyidae Bombyliidae Syrphidae Tephritidae Asilidae Mycetophilidae Muscidae Dolichopodidae Chloropidae far 11 taxonomic phylogenetic specialists 30000 30 00 300,0 6 ~ 213 13 2,1 5 3000 3 0 300, 21 2,
15.
Deep sea ecosystem exploration and ‘health check’: sampling strategy and methods applied during the iAtlantic_BR10_Petrobras cruise in the Santos Basin, Southwest Atlantic health check check’ iAtlanticBR10Petrobras iAtlanticBRPetrobras iAtlantic BR10 Petrobras BR Basin iAtlanticBR BR1
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Perez, Jose Angel A.
; Barros Neto, Halésio M.C. de
; Arantes, Renata C.M.
; Gaurisas, Daniela Y.
; Silva, Camila F.
; Alves, Fernanda Maria M.
; Costa, Júlia A.
; Eloi, Paula D.C.
; Fonseca, Thayse S.
; Gavazzoni, Lucas
; Lonskis, Isabella da S.
; Nardi, Ricardo U.
; Nascimento, Pedro O.
; Rodrigues, João Vitor M.
; Santos, Ana Lara F. dos
; Santos, Edson C. dos
; Schroeder, Rafael
; Silva, Luis Carlos da
; Souza, Fernanda dos S.S. de
; Bernardino, Ângelo F.
; Cavalcanti, Guarani H.
; Lindner, Alberto
; Mahiques, Michel M. de
; Millo, Christian
; Reis, Priscila
; Sweetman, Andrew K.
; Roberts, J. Murray
.
Abstract The iAtlantic Project has established an international collaborative strategy to improve mapping and characterization of deep and open ocean ecosystems in understudied regions of the Atlantic and evaluate their health. In December 2022, the first iAtlantic expedition in the South Atlantic set off to map and explore seafloor ecosystems in the Santos Basin slope (200-1,000 m depths) in collaboration with the Petrobras ‘Santos Basin - Regional Characterization Project.’ The 17-day ‘iAtlantic_BR10-Petrobras’ cruise was conducted on board the research vessel NPqHOc Vital de Oliveira (Brazilian Navy) and performed (a) water column structure characterization, (b) seafloor morphology mapping, (c) description of benthic habitats and communities by seafloor imagery and biological/ geological sampling, and (d) ex-situ experiments to assess the functioning of sedimentary ecosystems and their responses to climate-related environmental changes. This study describes the rationale behind the iAtlantic_BR10-Petrobras cruise science plan, reports its sampling strategy and methods, and summarizes its collected data and preliminary results. health 2022 2001,000 2001000 200 1,000 1 000 (200-1,00 depths Project. 17day day 17 ‘iAtlantic_BR10Petrobras iAtlanticBR10Petrobras iAtlanticBRPetrobras ‘iAtlantic_BR10 BR10 BR ‘iAtlantic_BR10-Petrobras Brazilian Navy a (a b (b c (c biological d (d exsitu ex situ climaterelated climate related changes iAtlantic_BR10Petrobras iAtlantic_BR10 plan methods results 202 2001 2001,00 200100 20 1000 1,00 00 (200-1,0 BR10Petrobras iAtlanticBR iAtlanticBR10 ‘iAtlantic_BR1 BR1 iAtlantic_BR1 2001,0 20010 2 100 1,0 0 (200-1, BRPetrobras iAtlanticBR1 ‘iAtlantic_BR iAtlantic_BR 2001, 10 1, (200-1 (200- (200 (20 (2 (
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