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Urinary symptoms, falls and fear of falling in older people with cognitive impairment symptoms
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Bernardes, Raquel Santana

; Barros, Regina de Sousa

; Silva, Felipe Sousa da

; Pequeno, Serise Amaral

; Alves, Aline Teixeira

; Garcia, Patrícia Azevedo

Fisioterapia em Movimento

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2024, Volume 37 elocation e37116

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Introdução: Entre as síndromes geriátricas, destacam-se o comprometimento cognitivo, a incontinência urinária, a noctúria e as quedas. Idosos com incontinência urinária são mais propensos a cair e apresentar medo de cair. Objetivo: Investigar a frequência de incontinência urinária e noctúria e avaliar a associação dessas variáveis com a ocorrência de quedas e com o medo de cair em idosos com comprometimento cognitivo. Métodos: Estudo transversal com idosos encaminhados das Unidades Básicas de Saúde com comprometimento cognitivo avaliados entre os anos de 2019 e 2021. Foram coletadas informações sobre incontinência urinária, noctúria, histórico de quedas e medo de cair, fornecidas pelos idosos e seus acompanhantes. Os dados foram analisados por meio dos testes quiquadrado e regressões logísticas univariadas. Resultados: Foram analisados dados de 89 idosos, dos quais 58,4% apresentavam incontinência urinária, 28,1% apresentavam noctúria, 67,4% tinham medo de cair e 41,6% relataram quedas nos últimos seis meses. O grupo com incontinência urinária [2(1) = 5,147; p = 0,023] e o grupo com noctúria [χ2(1) = 4,353; p = 0,037] apresentaram frequências significativamente maiores de medo de cair. Não foram observadas diferenças das frequências de histórico de quedas entre os indivíduos com e sem incontinência ou noctúria (p > 0,05). O medo de cair mostrouse associado à incontinência (OR = 2,833; IC95% 1,137 – 7,062) e à noctúria (OR = 3,365; IC 95% 1,033 – 10,966). Conclusão: Idosos com comprometimento cognitivo apresentam alta frequência de incontinência urinária, noctúria, quedas e medo de cair. Ademais, há associação da incontinência urinária e da noctúria com o medo de cair nessa população. Introdução geriátricas destacamse destacam se Objetivo Métodos 201 2021 acompanhantes univariadas Resultados 8 584 58 4 58,4 281 28 1 28,1 674 67 67,4 416 41 6 41,6 meses 21 2 [2(1 5,147 5147 5 147 0,023 0023 0 023 χ21 χ χ2 [χ2(1 4,353 4353 353 0,037 0037 037 0,05. 005 0,05 . 05 0,05) OR 2,833 2833 833 IC95 1137 137 1,13 7,062 7062 7 062 3,365 3365 3 365 95 1033 033 1,03 10,966. 10966 10,966 10 966 10,966) Conclusão Ademais população 20 202 58, 28, 67, 41, [2( 5,14 514 14 0,02 002 02 [χ2( 4,35 435 35 0,03 003 03 00 0,0 2,83 283 83 IC9 113 13 1,1 7,06 706 06 3,36 336 36 9 103 1,0 1096 10,96 96 [2 5,1 51 [χ2 4,3 43 0, 2,8 11 1, 7,0 70 3,3 33 109 10,9 [ 5, [χ 4, 2, 7, 3, 10,

Abstract Introduction: Among geriatric syndromes, cognitive impairment, urinary incontinence, nocturia, and falls stand out. Older adults with urinary incontinence are more prone to falls and exhibit fear of falling. Objective: To investigate the frequency of urinary incontinence and nocturia and evaluate the association of these variables with falls and fear of falling in older individuals with cognitive impairment. Methods: Cross-sectional study with older adults referred from Basic Health Units with cognitive impairment evaluated between 2019 and 2021. Information on urinary incontinence, nocturia, history of falls, and fear of falling provided by the participants and their caregivers was collected. Data were analyzed using Chi-square tests and univariate logistic regressions. Results: Data from 89 older adults were analyzed, of whom 58.4% had urinary incontinence, 28.1% had nocturia, 67.4% reported fear of falling, and 41.6% reported falls in the last six months. The group with urinary incontinence [χ2(1) = 5.147; p = 0.023] and the group with nocturia [χ2(1) = 4.353; p = 0.037] had significantly higher frequencies of fear of falling. No differences in the frequencies of history of falls were observed between individuals with and without urinary incontinence or nocturia (p > 0.05). Fear of falling was associated with urinary incontinence (OR = 2.833; 95% CI 1.137 – 7.062) and nocturia (OR = 3.365; 95% CI 1.033 – 10.966). Conclusion: Older adults with cognitive impairment have a high frequency of urinary incontinence, nocturia, falls, and fear of falling. Furthermore, there is an association between urinary incontinence, nocturia and fear of falling in this population. Introduction syndromes out Objective Methods Crosssectional Cross sectional 201 2021 collected Chisquare Chi square regressions Results 8 584 58 4 58.4 281 28 1 28.1 674 67 67.4 416 41 6 41.6 months χ21 χ χ2 [χ2(1 5.147 5147 5 147 0.023 0023 0 023 4.353 4353 353 0.037 0037 037 0.05. 005 0.05 . 05 0.05) OR 2.833 2833 2 833 95 1137 137 1.13 7.062 7062 7 062 3.365 3365 3 365 1033 033 1.03 10.966. 10966 10.966 10 966 10.966) Conclusion Furthermore population 20 202 58. 28. 67. 41. [χ2( 5.14 514 14 0.02 002 02 4.35 435 35 0.03 003 03 00 0.0 2.83 283 83 9 113 13 1.1 7.06 706 06 3.36 336 36 103 1.0 1096 10.96 96 [χ2 5.1 51 4.3 43 0. 2.8 11 1. 7.0 70 3.3 33 109 10.9 [χ 5. 4. 2. 7. 3. 10.

https://doi.org/10.1590/fm.2024.37116

Safety of CoronaVac and ChAdOx1 vaccines against SARS-CoV-2 in patients with rheumatoid arthritis: data from the Brazilian multicentric study safer ChAdOx SARSCoV2 SARSCoV SARS CoV 2 SARS-CoV- arthritis SARS-CoV
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Cruz, Vitor Alves

; Guimarães, Camila

; Rêgo, Jozelia

; Machado, Ketty Lysie Libardi Lira

; Miyamoto, Samira Tatiyama

; Burian, Ana Paula Neves

; Dias, Laiza Hombre

; Pretti, Flavia Zon

; Batista, Danielle Cristina Filgueira Alves

; Mill, José Geraldo

; Oliveira, Yasmin Gurtler Pinheiro de

; Gadelha, Carolina Strauss Estevez

; Gouveia, Maria da Penha Gomes

; Moulin, Anna Carolina Simões

; Souza, Bárbara Oliveira

; Aguiar, Laura Gonçalves Rodrigues

; Vieira, Gabriel Smith Sobral

; Grillo, Luiza Lorenzoni

; Lima, Marina Deorce de

; Pasti, Laís Pizzol

; Surlo, Heitor Filipe

; Faé, Filipe

; Moulaz, Isac Ribeiro

; Macabú, Mariana de Oliveira

; Ribeiro, Priscila Dias Cardoso

; Magalhães, Vanessa de Oliveira

; Aguiar, Mariana Freitas de

; Biegelmeyer, Erika

; Peixoto;, Flávia Maria Matos Melo Campos

; Kayser, Cristiane

; Souza, Alexandre Wagner Silva de

; Castro, Charlles Heldan de Moura

; Ribeiro, Sandra Lúcia Euzébio

; Telles, Camila Maria Paiva França

; Bühring, Juliana

; Lima, Raquel Lima de

; Santos, Sérgio Henrique Oliveira Dos

; Dias, Samuel Elias Basualto

; Melo, Natália Seixas de

; Sanches, Rosely Holanda da Silva

; Boechat, Antonio Luiz

; Sartori, Natália Sarzi

; Hax, Vanessa

; Dória, Lucas Denardi

; Rezende, Rodrigo Poubel Vieira de

; Baptista, Katia Lino

; Fortes, Natália Rodrigues Querido

; Melo, Ana Karla Guedes de

; Melo, Tâmara Santos

; Vieira, Rejane Maria Rodrigues de Abreu

; Vieira, Adah Sophia Rodrigues

; Kakehasi, Adriana Maria

; Tavares, Anna Carolina Faria Moreira Gomes

; Landa, Aline Teixeira de

; Costa, Pollyana Vitoria Thomaz da

; Azevedo, Valderilio Feijó

; Martins-Filho, Olindo Assis

; Peruhype-Magalhães, Vanessa

; Pinheiro, Marcelo de Medeiros

; Monticielo, Odirlei André

; Reis-neto, Edgard Torres Dos

; Ferreira, Gilda Aparecida

; Souza, Viviane Angelina de

; Teixeira-Carvalho, Andréa

; Xavier, Ricardo Machado

; Sato, Emilia Inoue

; Valim, Valeria

; Pileggi, Gecilmara Salviato

; Silva, Nilzio Antonio da

Advances in Rheumatology

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2024, Volume 64 elocation 58

Abstract: En | Text: En | PDF: En

Abstract Background Patients with immune-mediated rheumatic diseases (IMRDs) have been prioritized for COVID-19 vaccination to mitigate the infection severity risks. Patients with rheumatoid arthritis (RA) are at a high risk of severe COVID-19 outcomes, especially those under immunosuppression or with associated comorbidities. However, few studies have assessed the safety of the COVID-19 vaccine in patients with RA. Objective To evaluate the safety of vaccines against SARS-CoV-2 in patients with RA. Methods This data are from the study “Safety and Efficacy on COVID-19 Vaccine in Rheumatic Diseases,” a Brazilian multicentric prospective phase IV study to evaluate COVID-19 vaccine in IMRDs in Brazil. Adverse events (AEs) in patients with RA of all centers were assessed after two doses of ChAdOx1 (Oxford/AstraZeneca) or CoronaVac (Sinovac/Butantan). Stratification of postvaccination AEs was performed using a diary, filled out daily and returned at the end of 28 days for each dose. Results A total of 188 patients with RA were include, 90% female. CoronaVac was used in 109 patients and ChAdOx1 in 79. Only mild AEs were observed, mainly after the first dose. The most common AEs after the first dose were pain at the injection (46,7%), headache (39,4%), arthralgia (39,4%), myalgia (30,5%) and fatigue (26,6%), and ChAdOx1 had a higher frequency of pain at the injection (66% vs 32 %, p < 0.001) arthralgia (62% vs 22%, p < 0.001) and myalgia (45% vs 20%, p < 0.001) compared to CoronaVac. The more common AEs after the second dose were pain at the injection (37%), arthralgia (31%), myalgia (23%), headache (21%) and fatigue (18%). Arthralgia (41,4% vs 25%, p = 0.02) and pain at injection (51,4% vs 27%, p = 0.001) were more common with ChAdOx1. No serious AEs were related. With Regard to RA activity level, no significant difference was observed between the three time periods for both COVID-19 vaccines. Conclusion In the comparison between the two immunizers in patients with RA, local reactions and musculoskeletal symptoms were more frequent with ChAdOx1 than with CoronaVac, especially after the first dose. In summary, the AE occurred mainly after the first dose, and were mild, like previous data from others immunizing agents in patients with rheumatoid arthritis. Vaccination did not worsen the degree of disease activity. immunemediated immune mediated (IMRDs COVID19 COVID 19 COVID-1 risks (RA outcomes comorbidities However SARSCoV2 SARSCoV SARS CoV 2 SARS-CoV- Safety Diseases, Diseases Brazil (AEs ChAdOx Oxford/AstraZeneca OxfordAstraZeneca Oxford AstraZeneca (Oxford/AstraZeneca Sinovac/Butantan. SinovacButantan Sinovac/Butantan . Sinovac Butantan (Sinovac/Butantan) diary 18 include 90 female 10 79 46,7%, 467 46,7% , 46 7 (46,7%) 39,4%, 394 39,4% 39 4 (39,4%) 30,5% 305 30 5 (30,5% 26,6%, 266 26,6% 26 6 (26,6%) 66% 66 (66 3 % 0.001 0001 0 001 62% 62 (62 22 22% 45% 45 (45 20 20% 37%, 37 37% (37%) 31%, 31 31% (31%) 23%, 23 23% (23%) 21% 21 (21% 18%. 18% (18%) 41,4% 414 41 (41,4 25 25% 0.02 002 02 51,4% 514 51 (51,4 27 27% related level summary COVID1 1 COVID- SARS-CoV (Sinovac/Butantan 9 46,7 (46,7% 39,4 (39,4% 30,5 (30,5 26,6 (26,6% (6 0.00 000 00 (4 (37% (31% (23% (21 (18% 41,4 (41, 0.0 51,4 (51, 46, (46,7 39, (39,4 30, (30, 26, (26,6 ( (37 (31 (23 (2 (18 41, (41 0. 51, (51 (46, (39, (30 (26, (3 (1 (5 (46 (39 (26

https://doi.org/10.1186/s42358-024-00397-5

Systemic Inflammatory Patterns in Ovarian Cancer Patients: Analysis of Cytokines, Chemokines, and Microparticles Patients Cytokines Chemokines
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Santiago, Aline Evangelista

; Paula, Sálua Oliveira Calil de

; Carvalho, Andréa Teixeira de

; Cândido, Eduardo Batista

; Furtado, Rafaela de Souza

; Silva Filho, Agnaldo Lopes da

Revista Brasileira de Ginecologia e Obstetrícia

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dec 2023, Volume 45 N. 12 Pages 780 - 789

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Objetivo Comparar os padrões de resposta inflamatória sistêmica em mulheres com câncer epitelial de ovário (CEO) ou sem evidência de doença maligna, bem como avaliar o perfil de respostas inflamatórias sistêmicas em tumores dos tipos 1 e 2. Esta é uma forma não invasiva e indireta de avaliar tanto a atividade tumoral quanto o papel do padrão inflamatório durante as respostas pró- e antitumorais. Métodos Ao todo, 56 pacientes foram avaliados prospectivamente: 30 mulheres sem evidência de doença maligna e 26 mulheres com CEO. A quantificação plasmática de citocinas, quimiocinas e micropartículas (MPs) foi realizada por citometria de fluxo. Resultados Os níveis plasmáticos das citocinas pró-inflamatórias interleucina-12 (IL12), interleucina-6 (IL-6), fator de necrose tumoral alfa (tumor necrosis factor alpha, TNF-α, em inglês), interleucina-1 beta (IL-1β), e interleucina-10 (IL-10), e da quimiocina de motivo C-X-C 9 (CXCL-9) e da quimiocina de motivo C-X-C 10 (CXCL-10) foram significativamente maiores em pacientes com EOC do que nos controles. Os níveis plasmáticos da citocina interleucina-17A (IL17A) e MPs derivados de células endoteliais foram menores em pacientes com CEO do que no grupo de controle. A frequência de leucócitos e de MPs derivadas de células endoteliais foi maior nos tumores de tipo 2 do que naqueles sem malignidade. Observou-se um número expressivo de citocinas e quimiocinas inflamatórias/regulatórias nos casos de CEO, além de correlações negativas e positivas entre elas, o que leva a uma maior complexidade dessas redes. Conclusão Este estudo mostrou que, por meio da construção de redes compostas por citocinas, quimiocinas e MPs, há maior resposta inflamatória sistêmica em pacientes com CEO e correlação mais complexa desses biomarcadores em tumores de tipo 2. (CEO pró antitumorais todo 5 prospectivamente 3 (MPs fluxo próinflamatórias interleucina12 interleucina 12 IL12, IL12 IL , (IL12) interleucina6 6 interleucina- IL6, IL6 (IL-6) tumor alpha TNFα, TNFα TNF α, α TNF-α inglês, inglês inglês) interleucina1 IL1β, IL1β ILβ 1β β (IL-1β) interleucina10 IL10, IL10 (IL-10) CXC C X CXCL9 CXCL (CXCL-9 CXCL10 (CXCL-10 controles interleucina17A interleucinaA 17A IL17A ILA (IL17A controle malignidade Observouse Observou se inflamatóriasregulatórias regulatórias elas IL1 (IL12 (IL-6 (IL-1β (IL-10 (CXCL- CXCL1 (CXCL-1 (IL1 (IL- (IL-1 (CXCL (IL

Abstract Objective To compare the patterns of systemic inflammatory response in women with epithelial ovarian cancer (EOC) or no evidence of malignant disease, as well as to evaluate the profile of systemic inflammatory responses in type-1 and type-2 tumors. This is a non-invasive and indirect way to assess both tumor activity and the role of the inflammatory pattern during pro- and antitumor responses. Materials and Methods We performed a prospective evaluation of 56 patients: 30 women without evidence of malignant disease and 26 women with EOC. The plasma quantification of cytokines, chemokines, and microparticles (MPs) was performed using flow cytometry. Results Plasma levels of proinflammatory cytokines interleukin-12 (IL12), interleukin-6 (IL-6), tumor necrosis factor alpha (TNF-α) interleukin-1 beta (IL-1β), and interleukin-10 (IL-10), and C-X-C motif chemokine ligand 9 (CXCL-9) and C-X-C motif chemokine ligand 10 (CXCL-10) were significantly higher in patients with EOC than in those in the control group. Plasma levels of cytokine interleukin-17A (IL-17A) and MPs derived from endothelial cells were lower in patients with EOC than in the control group. The frequency of leukocytes and MPs derived from endothelial cells was higher in type-2 tumors than in those without malignancy. We observed an expressive number of inflammatory/regulatory cytokines and chemokines in the cases of EOC, as well as negative and positive correlations involving them, which leads to a higher complexity of these networks. Conclusion The present study showed that, through the development of networks consisting of cytokines, chemokines, and MPs, there is a greater systemic inflammatory response in patients with EOC and a more complex correlation of these biomarkers in type-2 tumors. (EOC type1 type 1 type- type2 2 noninvasive non invasive pro 5 3 (MPs cytometry interleukin12 interleukin 12 IL12, IL12 IL , (IL12) interleukin6 6 interleukin- IL6, IL6 (IL-6) TNFα TNF α (TNF-α interleukin1 IL1β, IL1β ILβ 1β β (IL-1β) interleukin10 IL10, IL10 (IL-10) CXC C X CXCL9 CXCL (CXCL-9 CXCL10 (CXCL-10 group interleukin17A interleukinA 17A A IL17A ILA (IL-17A malignancy inflammatoryregulatory regulatory them that IL1 (IL12 (IL-6 (IL-1β (IL-10 (CXCL- CXCL1 (CXCL-1 (IL1 (IL- (IL-1 (CXCL (IL

https://doi.org/10.1055/s-0043-1772590

COVID-Inconfidentes - SARS-CoV-2 seroprevalence in two Brazilian urban areas in the fourth quarter 2020: study protocol and initial results
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Meireles, Adriana Lúcia

; Garcia Lourenção, Luciano

; Alves de Menezes Júnior, Luiz Antônio

; Nascimento Coletro, Hillary

; Sousa Justiniano, Irene Carolina

; Silva de Moura, Samara

; Popolino Diniz, Amanda

; da Silva Sabião, Thaís

; Sampaio Rocha, Ana Maria

; Batista, Aline Priscila

; Nunes Lage, Nara

; dos Santos Simões, Bárbara

; Ali Santos, Carolina

; de Deus Mendonça, Raquel

; de Souza Andrade, Amanda Cristina

; Furbino Barbosa, Keila

; Zumerle Masioli, Cássio

; Cardoso Carraro, Júlia Cristina

; Carvalho de Menezes, Mariana

; Rezende Macedo Nascimento, Renata Cristina

; Roever, Leonardo

; Teixeira Caiaffa, Waleska

; Lins Machado Coelho, George Luiz

Población y Salud en Mesoamérica

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dec 2023, Volume 21 N. 1 Pages 15 - 37

Abstract: En Es | Text: En Es | PDF: En | PDF: Es

Abstract Objective: To describe study protocol and initial results of research project COVID-Inconfidentes. Method: This paper described the methodological procedures adopted and the prevalence of the SARS-CoV-2 infection in the population. A household survey was conducted between October and December 2020, in two historic cities of Brazil's mining region. Anti-SARS-CoV-2 antibody was detected using the Wondfo® rapid test. The face-to face interview consisted of administration of a questionnaire containing registration data, sociodemographic and economic variables, living habits, general health condition, mental health, sleep habits, and eating and nutrition. Results: We evaluated 1,762 residents, of which 764 (43.4 %) were in Mariana and 998 (56.6 %) in Ouro Preto. For both cities, 51.9 % of the interviewees were female, with a predominance of the age range 35 to 59 years old (47.2 %). The prevalence of the SARS-CoV-2 infection was 5.5 % in both cities, 6.2 % in Ouro Preto, and 4.7 % in Mariana (p-value > 0.05). Conclusion: The study was effective to estimate the seroprevalence of infection by the virus and its findings will enable further analyses of the health conditions of the population related to social isolation and the risk of infection with SARS-CoV-2.

Resumen Describir el protocolo de estudio y los resultados iniciales del proyecto de investigación COVID Inconfidentes. Método: Este artículo describe los procedimientos metodológicos adoptados y la prevalencia de la infección por SARS-CoV-2 en la población. Se realizó una encuesta domiciliaria entre octubre y diciembre de 2020, en dos ciudades históricas de la región minera de Brasil. El anticuerpo anti-SARS-CoV-2 se detectó mediante la prueba rápida Wondfo®. La entrevista cara a cara consistió en la administración de un cuestionario que contenía datos de registro, variables sociodemográficas y económicas, hábitos de vida, estado general de salud, salud mental, hábitos de sueño, alimentación y nutrición. Resultados: Se evaluaron 1.762 habitantes, de los cuales 764 (43,4 %) estaban en Mariana y 998 (56,6 %) en Ouro Preto. Para ambas ciudades, el 51,9 % de los entrevistados eran del sexo femenino, con predominio del rango de edad de 35 a 59 años (47,2 %). La prevalencia de la infección por SARS-CoV-2 fue del 5,5 % en ambos municipios, del 6,2 % en Ouro Preto y del 4,7 % en Mariana (p > 0,05). Conclusión: El estudio fue efectivo para estimar la seroprevalencia de infección por el virus y sus hallazgos permitirán analizar más las condiciones de salud de la población relacionadas con el aislamiento social y el riesgo de infección por SARS-CoV-2.

https://doi.org/10.15517/psm.v21i1.53127

Affordances in the home environment of children at risk of developmental delay
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Santos, Janaína Araujo Teixeira

; Lima, Amanda Larissa Oliveira

; Silva, Letícia Dias dos Santos

; Braga, Fernanda da Costa

; Alécio, Marcelo Machado

; Chagas, Paula Silva de Carvalho

; Defilipo, Érica Cesário

; Toledo, Aline Martins de

; Gutierres Filho, Paulo José Barbosa

; Ayupe, Kênnea Martins Almeida

Revista Paulista de Pediatria

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2023, Volume 41 elocation e2022104

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO Objetivo Verificar a adequação das oportunidades de ação no ambiente doméstico de crianças em risco de atraso no desenvolvimento e identificar fatores associados à sua frequência. Métodos Este estudo transversal incluiu 97 famílias que responderam ao Affordances in the Home Environment for Motor Development - Infant Scale (AHEMD-IS) para 3–18 meses (n=63) ou o Self Report (AHEMD-SR) para 18–42 meses (n=34). O teste de Mann-Whitney foi utilizado para identificar as diferenças entre as frequências de oportunidades de ação entre os grupos. A regressão linear múltipla foi utilizada para verificar a associação entre o sexo da criança, o estado civil, a escolaridade e nível socioeconômico da mãe, as idades da criança e da mãe, o número de residentes da casa, a renda per capita e os escores do AHEMD (α=0,05). Resultados A frequência das oportunidades de ação dos domicílios no AHEMD-IS variou de menos do que adequado a excelente; enquanto, no AHEMD-SR, a maior predominância foi de média frequência. A oferta de estímulos no AHEMD-IS foi significativamente maior. O maior nível socioeconômico e o número de moradores da casa foram associados a maiores oportunidades de ação. Conclusões Quanto maior o nível socioeconômico e o número de moradores, maiores são as oportunidades de ação nos domicílios das crianças em risco de atraso. É necessário oferecer às famílias algumas alternativas para tornar os seus ambientes domésticos mais ricos em oportunidades de ação que favoreçam o desenvolvimento infantil. 9 AHEMDIS IS (AHEMD-IS 318 3 18 3–1 n=63 n63 n 63 (n=63 AHEMDSR SR (AHEMD-SR 1842 42 18–4 n=34. n34 n=34 . 34 (n=34) MannWhitney Mann Whitney grupos civil mãe α=0,05. α005 α α=0,05 0 05 (α=0,05) excelente enquanto AHEMDSR, SR, AHEMD-SR infantil 31 1 3– n=6 n6 6 (n=6 184 4 18– n3 n=3 (n=34 α00 α=0,0 (α=0,05 n= (n= (n=3 α0 α=0, (α=0,0 (n α=0 (α=0, α= (α=0 (α= (α

Abstract Objective: The aim of this study was to verify the adequacy of affordances in the home environment of children at risk of developmental delay and to identify factors associated with their frequency. Methods: The cross-sectional study included 97 families who responded to the Affordances in the Home Environment for Motor Development — Infant Scale (AHEMD-IS) for 3–18 months (n=63), or AHEMD – Self-Report (AHEMD-SR) for 18–42 months (n=34). The Mann-Whitney U test was used to identify the differences between the frequencies of affordances between the groups. Multiple linear regression was used to verify the association between the child’s sex, mother’s marital status, education, socioeconomic level, child and mother’s ages, house residents’ number, per capita income, and AHEMD scores (α=0.05). Results: The home affordances’ frequency in the AHEMD-IS ranged from less than adequate to excellent, while in the AHEMD-SR, the highest predominance was medium. The offer of stimuli in the AHEMD-IS was significantly higher. Higher socioeconomic level and house residents’ number were associated with greater affordances. Conclusions: The higher the socioeconomic level and house residents’ number, the greater the affordances in the homes of children at risk of delay. It is necessary to provide families with some alternatives to make their home environments richer in affordances that favor child development. Objective Methods crosssectional cross sectional 9 AHEMDIS IS (AHEMD-IS 318 3 18 3–1 n=63, n63 n n=63 , 63 (n=63) SelfReport Self Report AHEMDSR SR (AHEMD-SR 1842 42 18–4 n=34. n34 n=34 . 34 (n=34) MannWhitney Mann Whitney groups childs s sex mothers mother status education ages residents income α=0.05. α005 α α=0.05 0 05 (α=0.05) Results excellent AHEMDSR, SR, AHEMD-SR medium Conclusions development 31 1 3– n6 n=6 6 (n=63 184 4 18– n3 n=3 (n=34 α00 α=0.0 (α=0.05 n= (n=6 (n=3 α0 α=0. (α=0.0 (n= α=0 (α=0. (n α= (α=0 (α= (α

https://doi.org/10.1590/1984-0462/2023/41/2022104

Overview of Chagas disease surveillance in an endemic region in Southeastern Brazil
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Rafael, Aline Ferreira

; Ferreira, Raquel Aparecida

; Mota, Ariela Ferreira

; Damasceno, Renata Fiúza

; Menezes, Agna Soares da Silva

; Lopes, Bartolomeu Teixeira

; Paulo, Gustavo Libério de

; Sabino, Ester Cerdeira

; Ribeiro, Antônio Luiz Pinho

; Quintino, Nayara Dornela

; Vieira, Thallyta Maria

Revista do Instituto de Medicina Tropical de São Paulo

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2023, Volume 65 elocation e51

Abstract: En | Text: En | PDF: En

ABSTRACT Chagas disease (CD) is a neglected disease caused by the protozoan Trypanosoma cruzi. It has high morbidity and mortality rates and mainly affects socially vulnerable populations. This is a cross-sectional study, with retrospective and prospective data collection. Using questionnaires applied to environmental surveillance coordinators, we characterized the status of CD surveillance activities in municipalities endemic for the disease in Northern Minas Gerais State (MG) and Jequitinhonha Valley (Vale do Jequitinhonha). Moreover, we spatialized the vulnerability index for chronic CD in the study area. The population consisted of 22 environmental surveillance coordinators, active in 2020, from Northern MG and Jequitinhonha Valley, 21 municipalities included in the SaMi-Trop research project, and Montes Claros municipality. After applying the questionnaires to the coordinators, a descriptive analysis of the variables was performed. To characterize the active municipalities, the explanatory variables collected in the questionnaire were compared with the dichotomous variable. Bivariate descriptive analysis was performed. Finally, geoprocessing techniques were used to spatialize the data and prepare maps. Regarding the team of endemic combat agents (ECA), 90.9% reported the lack of a specific team for CD vector control actions. Of the 22 municipalities participating in this study, nine were active (41.1%). Only 25% (n=2) of active municipalities (9% of the municipalities studied) met the target of visiting 50% of households per year. Finally, 81.1% of the coordinators stated that in their municipality, they developed actions linked to primary health care (PHC). The implementation of CD surveillance activities weakened in the endemic region. Few municipalities have a surveillance team, with low regularity of active surveillance and noncompliance with the program’s goal. The results suggest insufficient recording of activities in the information system, considering that there are municipalities that report performing the activities, but no production record was observed in the system. (CD cruzi populations crosssectional cross sectional collection (MG Vale Jequitinhonha. . Jequitinhonha) Moreover area 2 2020 SaMiTrop SaMi Trop project municipality performed variable Finally maps ECA, ECA , (ECA) 909 90 9 90.9 41.1%. 411 41.1% 41 1 (41.1%) 25 n=2 n2 n (n=2 9% (9 studied 50 year 811 81 81.1 PHC. PHC (PHC) region programs program s goal system 202 (ECA 90. 41.1 4 (41.1% n= (n= ( 5 8 81. (PHC 20 41. (41.1 (n (41. (41 (4

https://doi.org/10.1590/s1678-9946202365051

COVID-19: perfil de trabalhadores brasileiros em uma companhia de mineração e a dinâmica dos casos comunitários COVID19 COVID 19 COVID-19 COVID1 1 COVID-1 COVID-
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Parajára, Magda do Carmo

; Silva, Juliana Ilídio da

; Menezes-Júnior, Luiz Antônio Alves de

; Sales, Aline Dayrell Ferreira

; Friche, Amélia Augusta de Lima

; Machado, Elaine Leandro

; Silva, Luiz Sérgio

; Andrade, Amanda Cristina de Souza

; Freitas, Silvia Nascimento de

; Caiaffa, Waleska Teixeira

; Meireles, Adriana Lúcia

Revista Brasileira de Saúde Ocupacional

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2023, Volume 48 elocation edepi13

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Objetivo: descrever o perfil de desfechos de COVID-19 em trabalhadores da mineração e a dinâmica dos casos nas unidades de mineração e seus respectivos municípios. Métodos: estudo de coorte e ecológico, com dados secundários clínico-epidemiológicos, sociodemográficos e ocupacionais de trabalhadores de mineradora multinacional no Brasil e de casos de COVID-19 nos cinco municípios onde as unidades estavam localizadas, de março de 2020 a abril de 2021. A incidência acumulada e média móvel (MM) de 7 dias dos casos foram calculadas e comparadas na unidade e respectivo município. Resultados: foram incluídos 17.523 trabalhadores; 88,4% eram do sexo masculino; e 22,6% tiveram pelo menos um resultado positivo. Os trabalhadores mais testados, com casos positivos, colocados em quarentena e com sintomas foram do sexo feminino, de meia-idade, morando e trabalhando no Rio de Janeiro, diretamente contratados pela mineradora, em turnos e ocupações de alto risco. Todas as unidades apresentaram uma incidência acumulada superior aos seus respectivos municípios. Três municípios apresentaram picos de COVID-19 com MM coincidindo com o aumento de casos entre trabalhadores de mineração. Conclusão: aproximadamente um quinto dos trabalhadores foram diagnosticados com COVID-19, e a distribuição temporal dos casos nas unidades de mineração foi semelhante àquela dos municípios onde estavam localizadas. Objetivo COVID19 COVID 19 COVID-1 Métodos ecológico clínicoepidemiológicos, clínicoepidemiológicos clínico epidemiológicos, epidemiológicos clínico-epidemiológicos localizadas 202 2021 (MM município Resultados 17523 17 523 17.52 884 88 4 88,4 masculino 226 22 6 22,6 positivo testados positivos feminino meiaidade, meiaidade meia idade, idade meia-idade Janeiro risco Conclusão COVID19, 19, COVID1 1 COVID- 20 1752 52 17.5 8 88, 2 22, 175 5 17.

Abstract Objective: to describe the COVID-19 clinical outcomes profile from mining workers and the cases dynamic within the mining units and their respective municipalities. Methods: a cohort and ecological study using workers clinical-epidemiological, sociodemographic, and occupational secondary data of a multinational mining company, and of COVID-19 cases from five municipalities where the mining units were located, in Brazil, between March 2020 to April 2021. We calculated the cases cumulative incidence and the 7-day moving average (MA), and compared at the mining unit and respective municipality. Results: the study included 17,523 workers, 88.4% male, and 22.6% had at least one positive result for COVID-19. The workers most tested, with positive results, placed in quarantine, and with symptoms were female, middle-aged, living and working in Rio de Janeiro state, directly hired by the mining company, in shift-work, and in high-risk occupations. All mining units presented a cumulative incidence higher than their respective municipalities. Three municipalities showed peaks of COVID-19 with MA cases coinciding with an increase in cases among mining workers. Conclusion: approximately one-fifth of workers were diagnosed with COVID-19. The mining units had a similar temporal distribution of COVID-19 cases to the municipalities where they were located. Objective COVID19 COVID 19 COVID-1 Methods clinicalepidemiological, clinicalepidemiological epidemiological, epidemiological clinical-epidemiological sociodemographic company located Brazil 202 2021 7day day 7 MA, , (MA) municipality Results 17523 17 523 17,52 884 88 4 88.4 male 226 22 6 22.6 COVID19. 19. tested results quarantine female middleaged, middleaged middle aged, aged middle-aged state shiftwork, shiftwork shift work, work shift-work highrisk high risk occupations Conclusion onefifth fifth COVID1 1 COVID- 20 (MA 1752 52 17,5 8 88. 2 22. 175 5 17,

https://doi.org/10.1590/2317-6369/13922pt2023v48edepi13

Estimation of Thermochemical Properties of Propellants Using Peng-Robinson Equation of State PengRobinson Peng Robinson
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Silva, Luciana Amorim da

; Dias, Ana Carolina Marotti

; Volskis, Hector Gabriel Teixeira

; Silva, José Daniel Langendorf da

; Anastacio, Aline Cardoso

; Peixoto, Fernando Cunha

Journal of Aerospace Technology and Management

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2023, Volume 15 elocation e2723

Abstract: En | Text: En | PDF: En

ABSTRACT Several aspects make nitrocellulose based powders adequate as a solid propellant for rockets and missiles and the prefe rable propellant to be used in firearms and artillery: it produces less smoke and less fouling than other propellants; its burning rate shows a well-defined relation to pressure and the composition of the gaseous mixture resulting from its decomposition by burning can be predicted with relatively high levels of accuracy. This last feature, if coupled with adequate thermodynamic models, leads to a reliable framework for the simulation of internal ballistics and, ultimately, to an efficient design. Some simpler models use an ideal gas approach, which is obviously not adequate, and some others perform corrections based on the Virial E quation of S tate for sake of algebraic simplicity. This work employs the Peng-Robinson equation of state to model the pressure-volume-temperature (PVT) behavior of the gases produced during the burning reaction, once it is known to be accurate in the high pressures obtained inside combustion chambers. The results were compared to experimental data obtained in a closed vessel device and showed that the Peng-Robinson equation of state could predict the chamber pressure with higher accuracy. artillery propellants welldefined well defined accuracy feature ultimately design approach simplicity PengRobinson Peng Robinson pressurevolumetemperature volume temperature PVT (PVT reaction chambers

https://doi.org/10.1590/jatm.v15.1318

Phytochemical and pharmacological reports of the hypoglycemic activity of the Moringa oleifera extracts
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Santos, Ariana da Silva

; Pimentel, Anderson Lopes

; Oliveira, João Victor Lessa de

; Silva, Michelle Teixeira da

; Silva, Fernanda Geny Calheiros

; Borges, Arthur Luy Tavares Ferreira

; Moura, Maria Aline Fidelis Barros de

; Silva, Sâmia Andrícia Souza da

; Nascimento, Ticiano Gomes do

Rodriguésia

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2022, Volume 73 elocation e01262021

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Moringa oleífera Lam. é uma planta arbórea pertencente à família Moringaceae distribuída em áreas tropicais e que tem ganhado enorme atenção nas últimas décadas. Esta pesquisa é uma revisão sobre a associação entre extratos aquosos de folhas de M. oleifera e diabetes mellitus e compreender suas funções farmacológicas e mecanismos subjacentes. O refinamento da pesquisa demonstrou o potencial farmacêutico da M. oleifera e seus fitoquímicos, dado seu efeito antidiabético. A análise prospectiva mostrou a quantidade de aplicação dentro do IPC A61K na área da saúde. Os metabólitos secundários presentes em M. oleifera, glucosinolatos, flavonóides e compostos fenólicos podem ser responsáveis, em parte, pelas ações hipoglicemiantes de controle da doença. Os glucosinolatos, quando metabolizados por enzimas salivares, dão origem a sulforafanos que atuam na prevenção do diabetes tipo 2 e na redução da resistência à insulina. Os flavonóides interagem com as enzimas intestinais modificando o metabolismo dos carboidratos, regulando os níveis glicêmicos, além de aumentar a sensibilidade à insulina. Os compostos fenólicos aumentam a expressão dos transportadores de glicose (GLUT4) e reduzem a síntese de ácidos graxos e colesterol, contribuindo para a redução da resistência à glicose e controle da glicemia. Moringa oleifera pode ser usada como terapia complementar do diabetes tipo 2.

Abstract Moringa oleifera is an arboreal plant belonging to the family Moringaceae distributed in tropical areas and has gained enormous attention in the last decades. This research is a review on the association between aqueous extracts of M. oleifera leaves and diabetes mellitus and understanding its pharmacological functions and underlying mechanisms. The research refinement demonstrated the pharmaceutical potential of M. oleifera and its phytochemicals, given its antidiabetic effect. The prospective analysis showed the amount of application within IPC A61K in health area. The secondary metabolites present in M. oleifera, glucosinolates, flavonoids, and phenolic compounds may be responsible, in part, for the disease control hypoglycemic actions. Glucosinolates, when metabolized by salivary enzymes, give rise to sulforaphanes that act in preventing type 2 diabetes and in reducing insulin resistance. Flavonoids interact with intestinal enzymes by modifying carbohydrate metabolism by regulating glycemic levels, in addition to increasing insulin sensitivity. Phenolic compounds increase the expression of glucose transporters (GLUT4) and reduce the synthesis of fatty acids and cholesterol, contributing to the reduction of glucose resistance and blood sugar control. Moringa oleifera can be used as complementary therapy of the type-2 diabetes.

https://doi.org/10.1590/2175-7860202273090

10.

Prevalence and impact of urinary symptoms on quality of life during the last month of pregnancy
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Rett, Mariana Tirolli

; Santana, Jéssica Mota

; Paplinskie, Stephanie Anastacia

; Salata, Mariana Cecchi

; Lima, Élio Armando Nunes de

; Gallo, Rubneide Barreto Silva

; Alves, Aline Teixeira

Fisioterapia em Movimento

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2022, Volume 35 elocation e35143

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

Resumo Introdução As adaptações do organismo materno podem afetar negativamente o trato urinário inferior, levando a sintomas urinários e impacto na qualidade de vida (QV). Objetivo Determinar a prevalência de sintomas urinários e o impacto da incontinência urinária (IU) na QV durante o último mês de gestação. Métodos Estudo transversal retrospectivo envolvendo 96 mulheres no puerpério imediato, entrevistadas pessoalmente sobre sintomas urinários e QV durante as últimas quatro semanas de gestação. A amostra foi dividida em dois grupos, de acordo com o número de gestações: G1 = 1 gestação (n = 41) e G2 = ≥ 2 gestações (n = 55). Aquelas que relataram a presença de IU de esforço e/ou urge-incontinência responderam o International Consultation on Incontinence Questionnaire - Short Form (ICIQ-SF). Resultados Os sintomas mais comuns foram noctúria (90,6%), urgência (82,3%), frequência urinária (71,9%), sensação de esvaziamento incompleto (62,5%) e IU de esforço e/ou urge-incontinência (53,1%), sem diferença entre os grupos. Apenas a queixa de IU de esforço ao tossir foi significativamente maior no G2 (p = 0,04). Não houve diferença na QV entre os grupos baseando-se nos escores do ICIQ-SF, porém o G1 relatou impacto grave e o G2, impacto muito grave. Conclusão A maioria das mulheres referiu algum sintoma urinário, sendo mais prevalentes: noctúria, urgência, frequência urinária, sensação de esvaziamento incompleto e IU de esforço e/ou urge-incontinência. Entre aquelas com mais de duas gestações, a IU de esforço foi significativamente maior durante a tosse. Independente do número de gestações, a presença de algum sintoma de IU provocou impacto negativo na QV.

Abstract Introduction Adaptations of the maternal organism can adversely affect the lower urinary tract, leading to urinary symptoms with impact in quality of life (QoL). Objective To determine the prevalence of urinary symptoms and the impact of urinary incontinence (UI) on QoL during the last month of pregnancy. Methods Retrospective cross-sectional study, envolving 96 women in the immediate postpartum period personally interviewed about urinary symptoms and QoL during their last four weeks of gestation. Women were divided into two groups according to the number of pregnancies: G1 = 1 pregnancy (n = 41) and G2 = ≥ 2 pregnancies (n = 55). Those who reported the presence of stress urinary incontinence (SUI) and/or urge incontinence (UUI) were also administered the International Consultation on Incontinence Questionnaire - Short Form (ICIQ-SF). Results The most common symptoms were nocturia (90.6%), urgency (82.3%), urinary frequency (71.9%) feeling of incomplete emptying (62.5%) and SUI and/or UUI (53.1%) with no differences between groups. Only the complaint of SUI in cough was significantly higher in G2 (p = 0.04). There was no difference on QoL between groups based on ICIQ-SF scores among those with UI (53.1%), however G1 reported serious impact and G2 very serious impact. Conclusion Almost all women reported some type of urinary symptom and the most prevalent were nocturia, urgency, pollakiuria, feeling of incomplete emptying and SUI and/or UUI. SUI was more prevalent among women with two or more pregnancies and during cough were significantly higher. Regardless of the number of pregnancies, the presence any type of UI had a negative impact on QoL.

https://doi.org/10.1590/fm.2022.35143

11.

Burden and psychological symptoms on informal caregivers of the elderly in the COVID-19 pandemic COVID19 COVID 19 COVID-1 COVID1 1 COVID-
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Silva, Giuliana Duarte de Oliveira da

; Martins, Gabriela

; Rocha, Luana Aparecida da

; Machado, Mariane Teixeira

; Pott Junior, Henrique

; Gratão, Aline Cristina Martins

Revista Gaúcha de Enfermagem

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2022, Volume 43 N. spe elocation e20220163

Abstract: Es En Pt | Text: Es En Pt | PDF: Es | PDF: En | PDF: Pt

RESUMEN Objetivo Evaluar sobrecarga y los síntomas psicológicos de cuidadores informales de ancianos durante la pandemia de COVID-19. Método Estudio transversal con 50 cuidadores del Ambulatorio de Gerontología del interior de São Paulo, evaluados en 2021 mediante teleconsulta por la Escala de Ansiedad y Depresión Hospitalaria y Entrevista de Sobrecarga de Zarit. Se aplicó la Regresión multivariada de Poisson a las puntuaciones de los dos instrumentos en función de las características de los participantes. Resultados Los síntomas psicológicos destacaron en cuidadores con mayor tiempo de ejercicio (p=0,01; p=0,001) y que vivían en mismo ambiente que lo anciano (p=0,04; p=0,02). La sobrecarga asoció con edad (p<0,001) y convivencia con ancianos (p=0,001). Conclusión Existe una necesidad de intervenciones de mitigación de los síntomas psicológicos y sobrecarga en cuidadores mayores, que viven con ancianos y realizan la función por más tiempo. COVID19. COVID19 COVID 19. 19 COVID-19 5 Paulo 202 Zarit participantes p=0,01 p001 p 0 01 (p=0,01 p=0,001 p0001 001 p=0,04 p004 04 (p=0,04 p=0,02. p002 p=0,02 . 02 p=0,02) p<0,001 (p<0,001 p=0,001. (p=0,001) mayores COVID1 1 COVID-1 20 p=0,0 p00 (p=0,0 p=0,00 p000 00 p<0,00 (p<0,00 (p=0,001 COVID- 2 p=0, p0 (p=0, p<0,0 (p<0,0 (p=0,00 p=0 (p=0 p<0, (p<0, p= (p= p<0 (p<0 (p p< (p<

ABSTRACT Objective To evaluate the burden and psychological symptoms of informal caregivers of the elderly during the COVID-19 pandemic. Method Cross-sectional study with 50 caregivers from the Gerontology Outpatient Clinic in the interior of São Paulo, evaluated in 2021 via teleconsultation by the Hospital Anxiety and Depression Scale and the Zarit-Brief Burden Interview. Poisson’s multivariate regression was applied to the two instruments scores according to the set of characteristics of the participants. Results Psychological symptoms were highlighted in caregivers with longer time in exercise (p=0.01; p=0.001) and who lived in the same environment with the elderly (p=0.04; p=0.02). Burden was associated with age (p<0.001) and living with the elderly (p=0.001). Conclusion There is a need for interventions that attenuate psychological symptoms and burden in older caregivers, who live with the elderly and have been working for a longer time. COVID19 COVID 19 COVID-1 pandemic Crosssectional Cross sectional 5 Paulo 202 ZaritBrief Zarit Brief Interview Poissons Poisson s participants p=0.01 p001 p 0 01 (p=0.01 p=0.001 p0001 001 p=0.04 p004 04 (p=0.04 p=0.02. p002 p=0.02 . 02 p=0.02) p<0.001 (p<0.001 p=0.001. (p=0.001) COVID1 1 COVID- 20 p=0.0 p00 (p=0.0 p=0.00 p000 00 p<0.00 (p<0.00 (p=0.001 2 p=0. p0 (p=0. p<0.0 (p<0.0 (p=0.00 p=0 (p=0 p<0. (p<0. p= (p= p<0 (p<0 (p p< (p<

RESUMO Objetivo Avaliar sobrecarga e sintomas psicológicos dos cuidadores informais de idosos durante a pandemia da COVID-19. Método Estudo transversal com 50 cuidadores do Ambulatório de Gerontologia do interior de São Paulo, avaliados em 2021 via teleconsulta pela Escala Hospitalar de Ansiedade e Depressão e Entrevista de Sobrecarga de Zarit. A Regressão multivariada de Poisson foi aplicada nos escores dos dois instrumentos em função do conjunto de características dos participantes. Resultados Destacaram-se os sintomas psicológicos nos cuidadores com maior tempo em exercício (p=0,01; p=0,001) e que viviam no mesmo ambiente que o idoso (p=0,04; p=0,02). A sobrecarga associou-se com sua idade (p<0,001) e morar junto ao idoso (p=0,001). Conclusão Urgem intervenções atenuantes dos sintomas psicológicos e de sobrecarga nos cuidadores com idade avançada, que residem junto ao idoso e desempenham a função há maior tempo. COVID19. COVID19 COVID 19. 19 COVID-19 5 Paulo 202 Zarit participantes Destacaramse Destacaram se p=0,01 p001 p 0 01 (p=0,01 p=0,001 p0001 001 p=0,04 p004 04 (p=0,04 p=0,02. p002 p=0,02 . 02 p=0,02) associouse associou p<0,001 (p<0,001 p=0,001. (p=0,001) avançada COVID1 1 COVID-1 20 p=0,0 p00 (p=0,0 p=0,00 p000 00 p<0,00 (p<0,00 (p=0,001 COVID- 2 p=0, p0 (p=0, p<0,0 (p<0,0 (p=0,00 p=0 (p=0 p<0, (p<0, p= (p= p<0 (p<0 (p p< (p<

https://doi.org/10.1590/1983-1447.2022.20220163.en

12.

Segurança do paciente na Atenção Primária à Saúde: percepção da equipe de enfermagem
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Silva, Liliane de Lourdes Teixeira

; Dias, Felícia Cristina de Souza

; Maforte, Naiara Tauane Pires

; Menezes, Aline Carrilho

Escola Anna Nery

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2022, Volume 26 elocation e20210130

Abstract: Pt En Es | Text: Pt En Es | PDF: Pt | PDF: En | PDF: Es

RESUMO Objetivo compreender a percepção da equipe de enfermagem da Atenção Primária à Saúde sobre a segurança do paciente. Método estudo exploratório e descritivo com abordagem qualitativa com 22 profissionais da enfermagem atuantes na Atenção Primária à Saúde. Os dados foram coletados por meio de entrevistas semiestruturadas gravadas e analisados segundo a análise temática de conteúdo proposto por Bardin. Resultados emergiram três unidades temáticas: “O significado de segurança do paciente”, “Fatores contribuintes para a ocorrência de erros na assistência à saúde” e “Estratégias para a segurança do paciente”. A equipe de enfermagem desconhecia o Programa Nacional de Segurança do Paciente, mas destacaram ações de cuidado seguro e fatores que levam a ocorrência de erro, além de reconhecerem a necessidade de uma educação formal sobre a temática e melhoria do processo de trabalho e da comunicação com a alta gestão. Considerações finais e implicações para a prática o desconhecimento da equipe de enfermagem indica a necessidade de capacitá-la acerca da temática para subsidiar alterações no processo de trabalho com a incorporação de protocolos e de estratégias de mitigação e prevenção de eventos adversos na Atenção Primária à Saúde que garantam uma assistência mais capacitada e segura ao usuário.

ABSTRACT Objective to understand the perception of the Primary Health Care Nursing team on patient safety. Method this is an exploratory and descriptive study with a qualitative approach conducted with 22 Nursing professionals working in Primary Health Care. The data were collected through semi-structured interviews recorded and analyzed according to thematic content analysis proposed by Bardin. Results three thematic units emerged, namely: “The meaning of patient safety”, “Contributing factors to the occurrence of errors in health care” and “Strategies for patient safety”. The Nursing team was unaware of the National Patient Safety Program, but they highlighted safe care actions and factors that lead to the occurrence of errors, in addition to recognizing the need for formal education on the subject matter and improvement of the work process and communication with the senior management. Final considerations and implications for the practice lack of knowledge in the Nursing team indicates the need to train them on the theme to support changes in the work process with the incorporation of protocols and strategies for mitigating and preventing adverse events in Primary Care Health that guarantee more qualified and safer assistance to the user.

RESUMEN Objetivo comprender la percepción del equipo de enfermería de Atención Primaria de Salud sobre la seguridad del paciente. Método estudio exploratorio descriptivo con abordaje cualitativo, llevado a cabo con 22 profesionales de enfermería que se dedican a la Atención Primaria de la Salud. Los datos fueron recolectados a través de entrevistas semiestructuradas grabadas y analizadas de acuerdo al análisis de contenido temático propuesto por Bardin. Resultados surgieron tres unidades temáticas: “El significado de la seguridad del paciente”, “Factores que contribuyen a la ocurrencia de errores en la atención de la salud” y “Estrategias para la seguridad del paciente”. El personal de enfermería desconocía el Programa Nacional de Seguridad del Paciente, pero destacó acciones de cuidado seguro y factores que conducen a la ocurrencia de errores, además de reconocer la necesidad de educación formal en el tema y mejora del proceso de trabajo y comunicación con la administración. Consideraciones finales e implicaciones para la práctica el desconocimiento del equipo de enfermería indica la necesidad de que el mismo reciba formación en la temática para fomentar cambios en el proceso de trabajo con la incorporación de protocolos y estrategias de mitigación y prevención de eventos adversos en la Atención Primaria de la Salud que garanticen una asistencia más cualificada y segura al usuario.

https://doi.org/10.1590/2177-9465-ean-2021-0130 1 downloads

13.

Impact of treated sewage effluent on soil fertility, salinization, and heavy metal content
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Barbosa, Aline Michelle da Silva

; Faria, Rogério Teixeira de

; Saran, Luciana Maria

; Santos, Gilmar Oliveira

; Dantas, Geffson de Figueiredo

; Coelho, Anderson Prates

Bragantia

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2022, Volume 81 elocation e0222

Abstract: En | Text: En | PDF: En

ABSTRACT A long-term experiment (2013 to 2017) of treated sewage effluent (TSE) levels via fertigation in a humid tropical region was installed in Jaboticabal, state of São Paulo, Southeast of Brazil, to evaluate the impact of TSE on soil fertility and the potential for salinization and heavy metal contamination of an Oxisol. The area was cultivated with Urochloa brizantha under the application of four TSE levels at the irrigation depth (0, 11, 60, and 100% TSE) during the four years of the experiment. The TSE chemical composition was monitored throughout the experimental period. The heavy metal levels and soil fertility were evaluated in the 0-0.10 and 0.10-0.20 m layers at the end of the four years of the experiment. Fertigation using TSE did not increase the concentration of potentially toxic elements (As, Cd, Cu, Hg, Mo, Ni, Pb, Se, and Zn) in the soil due to their low concentration in the effluent. A higher Na concentration was also observed at high TSE levels (60 and 100%). However, the sodium adsorption rate in the TSE was low, generating no potential for soil salinization and sodification. Fertigation with TSE levels increased soil fertility, increasing by more than 10% the P content and base saturation in the soil compared to control. According to the chemical attributes evaluated in the soil and effluent, this long-term study showed that TSE application via fertigation in humid tropical regions on clayey soils cultivated with forage grasses is recommended.

https://doi.org/10.1590/1678-4499.20210224

14.

Toxicologia crítica aplicada aos agrotóxicos – perspectivas em defesa da vida
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Friedrich, Karen

; Gurgel, Aline do Monte

; Sarpa, Marcia

; Bedor, Cheila Nataly Galindo

; Siqueira, Marília Teixeira de

; Gurgel, Idê Gomes Dantas

; Augusto, Lia Giraldo da Silva

Saúde em Debate

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2022, Volume 46 N. spe2 Pages 293 - 315

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

RESUMO A toxicologia é aplicada aos processos regulatórios tendo como base central a linearidade das relações entre a dose e o efeito e a possibilidade de estabelecer condições de exposição seguras. Isso ocorre apesar das limitações apontadas pela literatura cientifica. A concepção, a definição das metodologias e a condução da avaliação de risco dos agrotóxicos acabam por atender aos interesses econômicos e à definição de cenários de segurança distantes da realidade. As limitações metodológicas dos estudos exigidos para fins de registro de um agrotóxico envolvem: a desconsideração das interações entre as misturas utilizadas; a não previsão de curvas dose-resposta não lineares (horméticas); a compartimentalização dos desfechos analisados; a exposição nos períodos críticos do desenvolvimento; e a desconsideração do contexto, das diversidades individuais, coletivas e dos territórios expostos aos agrotóxicos, entre outros aspectos discutido nesse ensaio. A toxicologia crítica propõe que a avaliação toxicológica parta da integralidade do problema no contexto apresentando propostas que podem ser adotadas nos processos de regulação de agrotóxicos e outras substâncias potencialmente perigosas.

ABSTRACT Toxicology is applied to regulatory processes based on the linear basis of the relationship between dose and effect and the possibility of establishing safe exposure conditions. This occurs despite the limitations pointed out by the scientific literature. The conception, definition of methodologies, and the conduct of risk assessment of pesticides ends up meeting economic interests and the definition of security scenarios that are far from reality. The methodological limitations of the studies required for the purpose of registering a pesticide involve: disregarding the interactions between the mixtures used; the failure to predict non-linear dose-response curves (hormetical); compartmentalization of the analyzed outcomes; exposure in critical periods of development; and disregarding of the context, individual and collective diversity and the territories exposed to pesticides, among other aspects discussed in this essay. Critical toxicology proposes that the toxicological assessment should start from the integrality of the problem in the context, presenting proposals that can be adopted in the regulation processes of pesticides and other potentially dangerous substances.

https://doi.org/10.1590/0103-11042022e220

15.

Toxicologia crítica aplicada aos agrotóxicos – perspectivas em defesa da vida
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Friedrich, Karen

; Gurgel, Aline do Monte

; Sarpa, Marcia

; Bedor, Cheila Nataly Galindo

; Siqueira, Marília Teixeira de

; Gurgel, Idê Gomes Dantas

; Augusto, Lia Giraldo da Silva

Saúde em Debate

Journal Metrics
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2022, Volume 46 N. spe2 Pages 293 - 315

Abstract: Pt En | Text: Pt En | PDF: Pt | PDF: En

https://doi.org/10.1590/0103-11042022e220

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